BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0412.0009.p (585 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00081277.1| COG3275: Putative regulator of cell autolysis... 153 1e-35 ref|NP_561843.1| two-component sensor histidine kinase [Clostrid... 151 4e-35 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 151 4e-35 ref|NP_563004.1| two-component sensor histidine kinase [Clostrid... 148 4e-34 ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halo... 147 7e-34 >ref|ZP_00081277.1| COG3275: Putative regulator of cell autolysis [Geobacter metallireducens] Length = 576 Score = 153 bits (387), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 90/208 (43%), Positives = 122/208 (58%), Gaps = 6/208 (2%) Query: 378 KSSELKALQAQINPHFLQNTLQMIGSMLFKNSPAESYGVLRSLSDMFRYIIREPEDLAPL 437 + +E++ALQAQINPHFL NT+ I S + SP + +L L+D FR I D PL Sbjct: 360 REAEIRALQAQINPHFLFNTINTIISYT-RTSPETASDLLVKLADFFRRNINPGGDSVPL 418 Query: 438 RAELNHLNNYMQIQQQRFAARLDYRLQVDEGALNSLIPKLTLQPITENAFFHG-LERQEG 496 EL H Y+ I++ RF RL VDE AL +P LTLQP+ ENA HG L R+EG Sbjct: 419 ATELEHCRAYIAIEKARFEDRLRVVFDVDEEALGCKLPTLTLQPLVENALKHGILPREEG 478 Query: 497 PWELEVKVSRTGEDTLIVIRDNGVGLEPDKLAELQRRLTSRSGKLWTYGERIGLSNVASR 556 E+ V R G IV+ DNGVG+ P+++A L + S +L T G I L+NV +R Sbjct: 479 -GEIRVGAHREGGVVRIVVGDNGVGMPPEQVARL---FSGESSQLPTEGAGIALNNVNAR 534 Query: 557 IHLHFGGSYGIQVESREGQGTTVTVTIP 584 + +G + ++VES G GTTV+ T+P Sbjct: 535 LSALYGPEHALRVESTPGAGTTVSFTVP 562 >ref|NP_561843.1| two-component sensor histidine kinase [Clostridium perfringens] dbj|BAB80633.1| two-component sensor histidine kinase [Clostridium perfringens str. 13] Length = 410 Score = 151 bits (382), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 77/209 (36%), Positives = 123/209 (58%), Gaps = 3/209 (1%) Query: 376 EKKSSELKALQAQINPHFLQNTLQMIGSMLFKNSPAESYGVLRSLSDMFRYIIREPEDLA 435 E K+ +LKALQ+QINPHFL N L I S+ ++ V+ +LS + RY +++ + Sbjct: 202 EYKACQLKALQSQINPHFLFNVLNSIASLAIIEDAPKTQEVIYNLSYILRYTLKKANKIV 261 Query: 436 PLRAELNHLNNYMQIQQQRFAARLDYRLQVDEGALNSLIPKLTLQPITENAFFHGLERQE 495 L E+NH+ Y++IQ+ RF R+ Y + DE N IP + LQ ENA HG+E +E Sbjct: 262 RLSEEINHVKAYLKIQKVRFGERIQYNIDFDEEDSNVQIPFMALQVFVENAVLHGIEEKE 321 Query: 496 GPWELEVKVSRTGEDTLIVIRDNGVGLEPDKLAELQRRLTSRSGKLWTYGERIGLSNVAS 555 + + + GED +I I D+GVG+ +KL E++ + SR KL +++G++NV Sbjct: 322 QGGVINLSIKSRGEDMIITISDDGVGISVEKLCEIRNEIKSRD-KLDL--DKVGINNVNK 378 Query: 556 RIHLHFGGSYGIQVESREGQGTTVTVTIP 584 R+ ++G Y I ++S+ +GT V + IP Sbjct: 379 RMFHYYGEEYSINIDSKVKKGTKVEIIIP 407 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 151 bits (382), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 88/261 (33%), Positives = 145/261 (55%), Gaps = 14/261 (5%) Query: 333 GMMKEREVRLSNRV-------DEIGLLETKLDQMSHRIREHIRTEYIISLEKKSSELKAL 385 M K R+ L +V DEI ++ + ++M RI + I + + K+ +ELKAL Sbjct: 334 SMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKAL 393 Query: 386 QAQINPHFLQNTLQMIGSMLFKNSPAESYGVLRSLSDMFRYIIREPEDLAPLRAELNHLN 445 +AQINPHFL NTL I K E ++ SLS +FR + E+ +R E + Sbjct: 394 EAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIE 453 Query: 446 NYMQIQQQRFAARLDYRLQVDEGALNSLIPKLTLQPITENAFFHGLERQEGPWELEVKVS 505 Y+ +Q +R+ + Y +++ + L+ IPKL LQP ENA HGLE +EV Sbjct: 454 RYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSEESFVEVIGE 513 Query: 506 RTGEDTLIVIRDNGVGLEPDKLAELQRRLTSRSGKLWTYGERIG--LSNVASRIHLHFGG 563 + GE+ +I+DNG G+ + L +L+R + S + + E++G + NV R+ L++G Sbjct: 514 KEGENLKFIIKDNGPGMSEETLEKLKRFIESENIE-----EKVGYAIRNVNERLRLYYGD 568 Query: 564 SYGIQVESREGQGTTVTVTIP 584 Y +++ESR+G+GTT+++ +P Sbjct: 569 KYELKIESRQGEGTTISLILP 589 >ref|NP_563004.1| two-component sensor histidine kinase [Clostridium perfringens] dbj|BAB81794.1| two-component sensor histidine kinase [Clostridium perfringens str. 13] Length = 578 Score = 148 bits (373), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 78/244 (31%), Positives = 134/244 (54%), Gaps = 5/244 (2%) Query: 342 LSNRVDEIGLLETKLDQMSHRIREHIRTEYIISLEKKSSELKALQAQINPHFLQNTLQMI 401 LS DEI + ++M ++ +HIR Y+ L ++ +E+ ALQ QINPHFL NTL+ I Sbjct: 336 LSKDRDEITFIADNFNKMCEKLNDHIRKSYLAELRQREAEIVALQNQINPHFLYNTLESI 395 Query: 402 GSMLFKNSPAESYGVLRSLSDMFRYIIREPEDLAPLRAELNHLNNYMQIQQQRFAARLDY 461 N E +L SL+ +FR ++ + + E+ + N Y+++ + R+ + + Sbjct: 396 RMKAICNGDKEVGKMLYSLAFLFRSQVK-GNLIVSIDQEIKYCNKYLELFKFRYDEKFKF 454 Query: 462 RLQVDEGALNSLIPKLTLQPITENAFFHGLERQEGPWELEVKVSRTGEDTLIVIRDNGVG 521 +++ +E + I K TLQP+ EN F HG+ + EL++ + + ED ++ + DNG G Sbjct: 455 KIECEEDLYDKGIVKFTLQPLIENYFVHGIRLERDDNELKIYIYKHLEDIVVEVIDNGRG 514 Query: 522 LEPDKLAELQRRLTSRSGKLWTYGERIGLSNVASRIHLHFGGSYGIQVESREGQGTTVTV 581 + +KL ++ RR+ G+ IG+ NV RI + +G YG+ V S E +GT + + Sbjct: 515 IPKEKLDDINRRIRECDHS----GKSIGMLNVHERIKIKYGEPYGLTVTSEENKGTNMIL 570 Query: 582 TIPL 585 PL Sbjct: 571 KFPL 574 >ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halodurans] pir||F83913 hypothetical protein BH2110 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05829.1| BH2110~unknown conserved protein [Bacillus halodurans] Length = 585 Score = 147 bits (371), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 85/270 (31%), Positives = 144/270 (53%), Gaps = 14/270 (5%) Query: 325 LARYVQGFGMMKEREVRLSN---RVDEIGLLETKLDQMSHRIREHIRTEYIISLEKKS-- 379 L R ++ MK+++ + N DEIG L + ++MS I I Y ++EKK Sbjct: 312 LLRVLKHMKRMKKQKFDIINFPGDKDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQ 371 Query: 380 -----SELKALQAQINPHFLQNTLQMIGSMLFKNSPAESYGVLRSLSDMFRYIIREPEDL 434 ++L ALQ+QINPHFL N L+ I E+ ++++++ +FR + +D Sbjct: 372 LREKQAQLSALQSQINPHFLFNALETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDW 431 Query: 435 APLRAELNHLNNYMQIQQQRFAARLDYRLQVDEGALNSLIPKLTLQPITENAFFHGLERQ 494 +R EL + +++IQ+ RF +++Y L +DE A + +IP + P ENA HG+E Sbjct: 432 VTVRDELCLIICFLEIQKYRFGDKMEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESV 491 Query: 495 EGPWELEVKVSRTGEDTLIVIRDNGVGLEPDKLAELQRRLTSRSGKLWTYGERIGLSNVA 554 + ++++V + + + I DNG G++ +KLA L L + GE +G+ NV Sbjct: 492 KEKGIIQIRVEKNDGEIVYEISDNGAGMDEEKLASLIETLKNEEN----MGENVGIKNVY 547 Query: 555 SRIHLHFGGSYGIQVESREGQGTTVTVTIP 584 R+ LH+ + + SR GQGTTV + +P Sbjct: 548 YRLKLHYKNHFDFSINSRPGQGTTVQIKLP 577 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 784,684,887 Number of extensions: 31557291 Number of successful extensions: 104609 Number of sequences better than 1.0e-05: 184 Number of HSP's gapped: 104399 Number of HSP's successfully gapped: 184 Length of query: 585 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 454 Effective length of database: 401,559,609 Effective search space: 182308062486 Effective search space used: 182308062486 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)