BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0405.0005.p (200 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_979909.1| transcriptional regulator, TetR family [Bacillu... 88 9e-17 ref|NP_657503.1| tetR, Bacterial regulatory proteins, tetR famil... 88 9e-17 ref|NP_833324.1| Transcriptional regulator, TetR family [Bacillu... 88 1e-16 ref|NP_241868.1| transcriptional regulator (TetR family) [Bacill... 80 3e-14 ref|NP_244198.1| BH3332~unknown conserved protein in others [Bac... 74 2e-12 >ref|NP_979909.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS42517.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 197 Score = 88.2 bits (217), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 54/194 (27%), Positives = 100/194 (51%), Gaps = 1/194 (0%) Query: 1 MNGFEKRAALIKSKIMKTTMELLKTWEIKKLRIADIAKAAGVSQVTIYNYFGSKEALISE 60 MNGFEK K I + L +++I IAK A VSQVTIYN+FGSK+AL E Sbjct: 1 MNGFEKVKEKKKRAIKEAAFLLFSERGFNEVKIEHIAKEANVSQVTIYNHFGSKDALFRE 60 Query: 61 SFKDFVXXXXXXXXXXMRQQKTLKERITYFIFKDKETYSTLDPALVKEIMFDDEAMYQYI 120 ++F+ ++ + + I + T P ++ ++M DE + ++I Sbjct: 61 LIQEFIISEFQYYKDLAAEKLPFHDMMQKMIVRKMNTGGLFQPDMLLQMMQRDEELRKFI 120 Query: 121 QQQYDDRVMPLMVQMVEEGKASGEISQKVSMEAVLVMIQMYIKSSGEMLDSVAKHEDKNQ 180 +++++P ++++E+ + EI+ ++ E +L+ IQM+ K G+ + D+ + Sbjct: 121 YSYQNEKILPWYLEILEQAQQKNEINPHLTKEMMLLYIQMFTK-LGDDFGAQLLERDREK 179 Query: 181 FLDELFHIFFYGLC 194 + ++ +FFYGL Sbjct: 180 HIQDIVTMFFYGLS 193 >ref|NP_657503.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_845919.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP27405.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 197 Score = 88.2 bits (217), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 54/194 (27%), Positives = 100/194 (51%), Gaps = 1/194 (0%) Query: 1 MNGFEKRAALIKSKIMKTTMELLKTWEIKKLRIADIAKAAGVSQVTIYNYFGSKEALISE 60 MNGFEK K I + L +++I IAK A VSQVTIYN+FGSK+AL E Sbjct: 1 MNGFEKVKEKKKRAIKEAAFLLFSERGFNEVKIEHIAKEANVSQVTIYNHFGSKDALFRE 60 Query: 61 SFKDFVXXXXXXXXXXMRQQKTLKERITYFIFKDKETYSTLDPALVKEIMFDDEAMYQYI 120 ++F+ ++ + + I + T P ++ ++M DE + ++I Sbjct: 61 LIQEFIICEFQYYKELAEEKLPFHDMMQKMIVRKMNTGGLFQPDMLLQMMQRDEILREFI 120 Query: 121 QQQYDDRVMPLMVQMVEEGKASGEISQKVSMEAVLVMIQMYIKSSGEMLDSVAKHEDKNQ 180 +++++P ++++E + + EI+ ++ E +L+ IQM+ K G+ + D+ + Sbjct: 121 YSYQNEKILPWYLEILERAQRNNEINPHLTKEMMLLYIQMFTK-LGDDFGAQLLEGDREK 179 Query: 181 FLDELFHIFFYGLC 194 + ++ +FFYGL Sbjct: 180 HIQDIVTMFFYGLS 193 >ref|NP_833324.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP10525.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 197 Score = 87.8 bits (216), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 53/194 (27%), Positives = 100/194 (51%), Gaps = 1/194 (0%) Query: 1 MNGFEKRAALIKSKIMKTTMELLKTWEIKKLRIADIAKAAGVSQVTIYNYFGSKEALISE 60 MNGFE+ K I + L +++I IAK A VSQVTIYN+FGSK+AL E Sbjct: 1 MNGFERVKEKKKRAIKEAAFVLFSERGFNEVKIEHIAKEANVSQVTIYNHFGSKDALFRE 60 Query: 61 SFKDFVXXXXXXXXXXMRQQKTLKERITYFIFKDKETYSTLDPALVKEIMFDDEAMYQYI 120 ++F+ ++ + + I + T P ++ ++M DE + ++I Sbjct: 61 LIQEFIISEFQYYKELAEEKLPFHDMMQKMIVRKMNTGGLFQPDMLLQMMQRDEELRKFI 120 Query: 121 QQQYDDRVMPLMVQMVEEGKASGEISQKVSMEAVLVMIQMYIKSSGEMLDSVAKHEDKNQ 180 +++++P ++++E+ + EI+ ++ E +L+ IQM+ K G+ + D+ + Sbjct: 121 YSYQNEKILPWYLEILEQAQRKNEINPHLTKEMMLLYIQMFTK-LGDEFGAQLLEGDREK 179 Query: 181 FLDELFHIFFYGLC 194 + ++ +FFYGL Sbjct: 180 HIKDIVTMFFYGLS 193 >ref|NP_241868.1| transcriptional regulator (TetR family) [Bacillus halodurans] pir||B83775 transcription regulator (TetR family) BH1002 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04721.1| transcriptional regulator (TetR family) [Bacillus halodurans] Length = 201 Score = 80.1 bits (196), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 55/195 (28%), Positives = 91/195 (46%), Gaps = 4/195 (2%) Query: 1 MNGFEKRAALIKSKIMKTTMELLKTWEIKKLRIADIAKAAGVSQVTIYNYFGSKEALISE 60 M+GF++R K I++ + L + ++K+ IA+IAK A VSQVTIYNYF SK L E Sbjct: 1 MDGFQRRKEQKKRDILEAALSLFMEYGLQKVSIAEIAKNANVSQVTIYNYFESKHNLTHE 60 Query: 61 SFKDFVXXXXXXXXXXMRQQKTLKERITYFIFKDKETYSTLDPALVKEIMFDDEAMYQYI 120 F ++ + K E+I +F+ KE + + +M + A Sbjct: 61 VFLYYMDKAVRDFEQTVYSDKPFPEKIKEIMFRKKEVARRIHEEFYQYLMKEYTANETIA 120 Query: 121 QQQYDDRVMPLMVQMVEEGKASGEISQKVSMEAVLVMIQMYIKSSGEMLDSVAKHEDKNQ 180 + Y + + +EGK G + +S EA++ YIK E + +E Sbjct: 121 ENDYMQNALQHFDHLFQEGKEQGYVDPSLSHEAII----FYIKMLNEYIQKEEVYEKILP 176 Query: 181 FLDELFHIFFYGLCG 195 +++ +FFYG+ G Sbjct: 177 LTEDITKLFFYGIMG 191 >ref|NP_244198.1| BH3332~unknown conserved protein in others [Bacillus halodurans] pir||D84066 hypothetical protein BH3332 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07051.1| BH3332~unknown conserved protein in others [Bacillus halodurans] Length = 195 Score = 73.6 bits (179), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 93/201 (46%), Gaps = 10/201 (4%) Query: 1 MNGFEKRAALIKSKIMKTTMELLKTWEIKKLRIADIAKAAGVSQVTIYNYFGSKEALISE 60 M+GFE+R +I L+ T+ K+ I +IA A VS TI+NYFG+KE L Sbjct: 1 MDGFERRKQKKMEQIFTAAFSLMATYGYAKVSINEIATEARVSPATIFNYFGTKEKLYKA 60 Query: 61 SFKDFVXXXXXXXXXXMRQQKTLKERIT-YFIFKDKETYSTLDPALVKEIMFDDEAMYQY 119 + ++ + + E++ F+ + K+ + K + D + +Q Sbjct: 61 TLDHWIEQQLSAYEGVLYSDRPFPEKVADIFVREAKQLKAFAHHTSAKNGV--DASPWQM 118 Query: 120 IQQQYDDRVMPLMVQMVEEGKASGEISQKVSMEAVLVMIQMYIKSSGEMLDSVAKHEDKN 179 I + +++V ++M+E GK G I+ S+ + MY+ L + ED + Sbjct: 119 ILESSEEKVQTFFLKMIEIGKQEGYIATAYSVSTMQRYFSMYMNE----LTRCFQEEDND 174 Query: 180 QF---LDELFHIFFYGLCGRE 197 +DEL H+FFYGL ++ Sbjct: 175 DISRQIDELLHLFFYGLVEKQ 195 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.134 0.367 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 243,464,433 Number of extensions: 7931192 Number of successful extensions: 25530 Number of sequences better than 1.0e-05: 13 Number of HSP's gapped: 25556 Number of HSP's successfully gapped: 13 Length of query: 200 Length of database: 757,237,578 Length adjustment: 119 Effective length of query: 81 Effective length of database: 434,140,797 Effective search space: 35165404557 Effective search space used: 35165404557 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 123 (52.0 bits)