BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0402.0035.p (511 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_976623.1| sensor histidine kinase [Bacillus cereus ATCC 1... 152 2e-35 ref|NP_830150.1| Two component system histidine kinase [Bacillus... 150 8e-35 ref|NP_842824.1| sensor histidine kinase [Bacillus anthracis str... 148 4e-34 ref|NP_978273.1| sensor histidine kinase, putative [Bacillus cer... 147 5e-34 ref|NP_654205.1| HATPase_c, Histidine kinase-like ATPases [Bacil... 143 9e-33 >ref|NP_976623.1| sensor histidine kinase [Bacillus cereus ATCC 10987] gb|AAS39231.1| sensor histidine kinase [Bacillus cereus ATCC 10987] Length = 501 Score = 152 bits (384), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 97/287 (33%), Positives = 165/287 (57%), Gaps = 19/287 (6%) Query: 233 RYMRTLE---QGTHTLYATDFEARIPLKYNNELSTMAAALNDMAEQIVVSRSKEK----- 284 R M+ +E +G + + RI K +E++++ +N+MAE+++ + KE+ Sbjct: 217 RKMKQIEAMAEGVKEIEKGNLAYRIEKKGEDEIASLTENINNMAEELMNNIEKERKLEKQ 276 Query: 285 --DFLLNISHDLRTPLTSIMGFLSLLKEKSYDSEPEKERYIEVLEERTGYLKKLIDEFFE 342 + + N+SHDLRTPLTSIMG+L LL++ Y+++ + + Y + ++ LK LI++ FE Sbjct: 277 KNELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFE 336 Query: 343 ISQLKWKPAVLNKSRVNMQELLRQVVEGYHPQSRDRRIETVLLLPDQSVHVEIDADLFVR 402 ++L + +L K V + ELL Q++E PQ+ + + V P++ + ID++ VR Sbjct: 337 YTKLTNEQVILEKQEVCINELLEQLIEELVPQAEEHGLTFVKKFPEERAYAAIDSEKMVR 396 Query: 403 VLENLLSNAFKYSRADTELTIRLREPVAENRRQCLLRLEMWSTPAQAMENGELNRLFDRF 462 V +NLL NA KYS+ D E+ + L+ RR + + + ++A EL LF+RF Sbjct: 397 VFDNLLMNAIKYSKDDGEIKVSLQ----RQRRDIQI---VIANHSEAFTREELASLFERF 449 Query: 463 YKGDSSRT--GEGAGLGLSIAAEIIRLHGGRLDAQIEGERLGMMIEL 507 YK D SR+ EG+GLGL+IA I+ L GG + A+ E + ++ L Sbjct: 450 YKKDQSRSRVTEGSGLGLAIAKSIVELQGGSIRAEYEDGVIQFVVSL 496 >ref|NP_830150.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] gb|AAP07351.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] Length = 501 Score = 150 bits (378), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 96/275 (34%), Positives = 158/275 (57%), Gaps = 19/275 (6%) Query: 233 RYMRTLE---QGTHTLYATDFEARIPLKYNNELSTMAAALNDMAEQIVVSRSKEK----- 284 R M+ +E QG + + RI K +E++ + +N+MAE+++ + KE+ Sbjct: 217 RKMKQIEAMAQGVKEIERGNLAYRIEKKGEDEIAALTENINNMAEELMNNIEKERKLEKQ 276 Query: 285 --DFLLNISHDLRTPLTSIMGFLSLLKEKSYDSEPEKERYIEVLEERTGYLKKLIDEFFE 342 + + N+SHDLRTPLTSIMG+L LL++ Y+++ + + Y + ++ LK LI++ FE Sbjct: 277 KNELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFE 336 Query: 343 ISQLKWKPAVLNKSRVNMQELLRQVVEGYHPQSRDRRIETVLLLPDQSVHVEIDADLFVR 402 ++L + VL K V + ELL Q++E PQ+ + + V P++ + ID++ VR Sbjct: 337 YTKLTNEQVVLEKQEVCVNELLEQLIEELVPQAEEHGLTFVKKFPEERAYASIDSEKMVR 396 Query: 403 VLENLLSNAFKYSRADTELTIRLREPVAENRRQCLLRLEMWSTPAQAMENGELNRLFDRF 462 V +NLL NA KYS+ D E+ + L+ RR + + + ++ EL LF+RF Sbjct: 397 VFDNLLMNAIKYSKDDGEIKVSLQ----RQRRDIQI---VIANHSEEFTREELANLFERF 449 Query: 463 YKGDSSRT--GEGAGLGLSIAAEIIRLHGGRLDAQ 495 YK D SR+ EG+GLGL+IA I+ L GG + A+ Sbjct: 450 YKKDQSRSRVTEGSGLGLAIAKSIVELQGGSIRAE 484 >ref|NP_842824.1| sensor histidine kinase [Bacillus anthracis str. Ames] gb|AAP24310.1| sensor histidine kinase [Bacillus anthracis str. Ames] Length = 501 Score = 148 bits (373), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 94/275 (34%), Positives = 162/275 (58%), Gaps = 19/275 (6%) Query: 233 RYMRTLE---QGTHTLYATDFEARIPLKYNNELSTMAAALNDMAEQIVVSRSKEK----- 284 R M+ +E +G + + RI K +E++++ +N+MAE+++ + KE+ Sbjct: 217 RKMKQIEAMAEGVKEIEKGNLAYRIEKKGEDEIASLTENINNMAEELMNNIEKERKLEKQ 276 Query: 285 --DFLLNISHDLRTPLTSIMGFLSLLKEKSYDSEPEKERYIEVLEERTGYLKKLIDEFFE 342 + + N+SHDLRTPLTSIMG+L LL++ Y+++ + + Y + ++ LK LI++ FE Sbjct: 277 KNELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFE 336 Query: 343 ISQLKWKPAVLNKSRVNMQELLRQVVEGYHPQSRDRRIETVLLLPDQSVHVEIDADLFVR 402 ++L + VL K V + ELL Q++E PQ+ + + V P++ + ID++ VR Sbjct: 337 YTKLTNEQVVLEKQEVCVNELLEQLIEELVPQAEEHGLTFVKKFPEERAYAAIDSEKMVR 396 Query: 403 VLENLLSNAFKYSRADTELTIRLREPVAENRRQCLLRLEMWSTPAQAMENGELNRLFDRF 462 V +NLL NA KYS+ D E+ + L+ R++ +++ + + ++ EL LF+RF Sbjct: 397 VFDNLLMNAIKYSKDDGEIKVSLQ------RQRWEIQI-VIANHSEEFTREELASLFERF 449 Query: 463 YKGDSSRT--GEGAGLGLSIAAEIIRLHGGRLDAQ 495 YK D SR+ EG+GLGL+IA I+ L GG + A+ Sbjct: 450 YKKDQSRSRVTEGSGLGLAIAKSIVELQGGSIRAE 484 >ref|NP_978273.1| sensor histidine kinase, putative [Bacillus cereus ATCC 10987] gb|AAS40881.1| sensor histidine kinase, putative [Bacillus cereus ATCC 10987] Length = 355 Score = 147 bits (372), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 84/253 (33%), Positives = 148/253 (58%), Gaps = 17/253 (6%) Query: 249 DFEARIPLKYNNELSTMAAALNDMAEQIVVSRSKEK-------DFLLNISHDLRTPLTSI 301 +FE IP+ N+E+ +AA +N MA+ + S EK + + NISHDLRTP+TS+ Sbjct: 90 NFEVHIPISKNDEIGELAANVNRMAKSLKESIENEKKSQEMKNEMISNISHDLRTPVTSL 149 Query: 302 MGFLSLLKEKSYDSEPEKERYIEVLEERTGYLKKLIDEFFEISQLKWKPAVLNKSRVNMQ 361 +G+ LL K + + E E+Y+ +L+ ++ LK +D+ E Q+ ++ L+KS VNM+ Sbjct: 150 IGYADLLGNKLHSNGEECEQYVSILKRKSYELKNQVDDLLEYCQINYREIELHKSVVNMK 209 Query: 362 ELLRQVVEGYHPQSRDRRIETVLLLPDQSVHVEIDADLFVRVLENLLSNAFKYSRADTEL 421 L+ Q++ + PQ D + + + D+ +HVE+D L VR+ EN++SN+ Y + E+ Sbjct: 210 ALMEQIMIDFVPQLDDADM-SFCIKGDKELHVEMDVALMVRLFENVISNSIMYGKDGKEI 268 Query: 422 TIRLREPVAENRRQCLLRLEMWSTPAQAMENGELNRLFDRFYKGDSSRTGE--GAGLGLS 479 I++ ++R + +E+ + Q + + L +F++FY+G+ SR+ G G+GL+ Sbjct: 269 VIQV------SKRDMNVEIEIKNF-GQCIPDENLPYVFEKFYRGEKSRSSHTGGKGMGLA 321 Query: 480 IAAEIIRLHGGRL 492 IA I LH G + Sbjct: 322 IARSIAELHKGDI 334 >ref|NP_654205.1| HATPase_c, Histidine kinase-like ATPases [Bacillus anthracis A2012] Length = 486 Score = 143 bits (361), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 92/272 (33%), Positives = 159/272 (58%), Gaps = 19/272 (6%) Query: 233 RYMRTLE---QGTHTLYATDFEARIPLKYNNELSTMAAALNDMAEQIVVSRSKEK----- 284 R M+ +E +G + + RI K +E++++ +N+MAE+++ + KE+ Sbjct: 217 RKMKQIEAMAEGVKEIEKGNLAYRIEKKGEDEIASLTENINNMAEELMNNIEKERKLEKQ 276 Query: 285 --DFLLNISHDLRTPLTSIMGFLSLLKEKSYDSEPEKERYIEVLEERTGYLKKLIDEFFE 342 + + N+SHDLRTPLTSIMG+L LL++ Y+++ + + Y + ++ LK LI++ FE Sbjct: 277 KNELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFE 336 Query: 343 ISQLKWKPAVLNKSRVNMQELLRQVVEGYHPQSRDRRIETVLLLPDQSVHVEIDADLFVR 402 ++L + VL K V + ELL Q++E PQ+ + + V P++ + ID++ VR Sbjct: 337 YTKLTNEQVVLEKQEVCVNELLEQLIEELVPQAEEHGLTFVKKFPEERAYAAIDSEKMVR 396 Query: 403 VLENLLSNAFKYSRADTELTIRLREPVAENRRQCLLRLEMWSTPAQAMENGELNRLFDRF 462 V +NLL NA KYS+ D E+ + L+ R++ +++ + + ++ EL L +RF Sbjct: 397 VFDNLLMNAIKYSKDDGEIKVSLQ------RQRWEIQI-VIANHSEEFTREELASLXERF 449 Query: 463 YKGDSSRT--GEGAGLGLSIAAEIIRLHGGRL 492 YK D SR+ EG+GLGL+IA I+ L GG + Sbjct: 450 YKKDQSRSRVTEGSGLGLAIAKSIVELQGGSI 481 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 690,687,963 Number of extensions: 27361954 Number of successful extensions: 86997 Number of sequences better than 1.0e-05: 3572 Number of HSP's gapped: 81959 Number of HSP's successfully gapped: 3587 Length of query: 511 Length of database: 757,237,578 Length adjustment: 130 Effective length of query: 381 Effective length of database: 404,274,708 Effective search space: 154028663748 Effective search space used: 154028663748 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)