BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0385.0011.p (1083 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_228880.1| hypothetical protein [Thermotoga maritima] >gi|... 369 e-100 ref|NP_624693.1| possible DNA-binding protein (putative secreted... 135 5e-30 ref|NP_813056.1| conserved hypothetical protein [Bacteroides the... 77 2e-12 dbj|BAD12237.1| alpha-L-rhamnosidase [Sphingomonas paucimobilis] 59 6e-07 gb|EAD21940.1| unknown [environmental sequence] 58 1e-06 >ref|NP_228880.1| hypothetical protein [Thermotoga maritima] pir||D72299 hypothetical protein TM1074 - Thermotoga maritima (strain MSB8) gb|AAD36151.1| hypothetical protein [Thermotoga maritima] Length = 986 Score = 369 bits (946), Expect = e-100, Method: Compositional matrix adjust. Identities = 197/530 (37%), Positives = 287/530 (54%), Gaps = 26/530 (4%) Query: 24 LKNPPAAYRSVPLWSWNDXXXXXXXXXXXXXMHRAGIGGFFMHARGGLQTPYMGEEWMEA 83 L+NP YR P WSWND M+ G GGFFMH+R GL T Y+ EEWM Sbjct: 6 LENPGVWYRPAPFWSWNDKLCEEELLRQIDEMYEKGYGGFFMHSRVGLVTEYLSEEWMRL 65 Query: 84 IRTSIEKSRELGMNAWFYDENGWPSGFADGKVPAKGLDYQQKRLVCEQAPFEDVPAERII 143 +R+ E +R+LGM AW YDE+ WPSGFA G VP + +++ K L + + P + I+ Sbjct: 66 VRSCAEHARKLGMLAWLYDEDKWPSGFAGGIVPLEKPEHRHKYLTLLKKD-QIKPEDEIL 124 Query: 144 GWXXXXXXXXXXYRLLPPGEEARADLRISYDVNPY-----YTDTLSSMAVKEFIDSTYER 198 ++ GEE R+ +P+ Y D LS + F+ ST+ER Sbjct: 125 K------------KIERDGEEFYVVKRVMKLGDPWFNGTCYVDLLSRETTEAFLRSTHER 172 Query: 199 YWKQFGEKYGGELSGIFTDEPQFGR------GALPWSFELEDMFIRRHGGNVKEVLPALF 252 Y K G+ + + GIFTDEP + R LPW+ + F+RR G ++++ L LF Sbjct: 173 YKKSCGDLFRVSIPGIFTDEPTYLRVHHPKETTLPWTERFPEEFLRRKGYDIRDHLEELF 232 Query: 253 LDTMGASRARYAYWETVTFMFTQAYAKQIGDWCAGKGWSATGHVVDEQELMHQVTSVGDP 312 + + RY +++ T +F + + WC G TGH + E L QV +G Sbjct: 233 FNVKDYMKVRYDFFDVATSLFIENFTIPYAKWCEENGIFMTGHYMAEDTLRGQVEWIGAA 292 Query: 313 MAFYEHLQIPGCDWLGRFVGNDAMVPKQVSSVARQLGKKRAITESFGCSGWNVSFADLKR 372 M YE++QIPG D L R + + KQVSS A QLGKK + E+FG +G +VSF K Sbjct: 293 MPHYEYMQIPGIDKLARHL-EQVVTIKQVSSAAEQLGKKWVLCETFGTTGQHVSFLHRKW 351 Query: 373 IGEWQFVHGINLLCQHLQGYSLRGLRKRDYPPSLFYQQPWWSEYKNFNDYFARLSLLLSE 432 I +WQ V G+ + HL YS+RG RKRDYPP+LFYQQPWW + +DYFARL+ ++++ Sbjct: 352 IADWQAVLGVTYINPHLSLYSMRGERKRDYPPNLFYQQPWWKNERFLSDYFARLNHIVTQ 411 Query: 433 GAAQAEVLLLHPVRTAWTLQRGGDYSAVIPYHEAFARLTRWLCQSLIEHDYGSEGIIAGH 492 G + +VL++HP+ +AW + D + +E F +T+ L + I+ +G E I++ H Sbjct: 412 GKREVKVLMIHPISSAWCVYSKFD-DEIDKLNELFDTITKELVANKIDFHFGDEMILSKH 470 Query: 493 GRVSGGSFIVGEAAYRVVIVPPSVTVDRRTAELLREFSAQGGTLIAFEPY 542 GRV VGE Y VV++PP + + T ELL + GG + + + Sbjct: 471 GRVKEAKLRVGEYEYEVVVLPPLLNLKSSTVELLNSLAENGGKVFVLKDF 520 Score = 84.0 bits (206), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 82/337 (24%), Positives = 147/337 (43%), Gaps = 47/337 (13%) Query: 747 DWEIVHADLNSLTLDNARLRVDGGEWSELQPVIFIQEQLLAYGRTVTAELEFAFAVGFDT 806 D+E+ N L +D GG + V I + +E++F V Sbjct: 675 DFEVKMNSFNVLPVDRVEYFEAGGRVFRNEFVSKIWYEFYRLPDGTPFRVEYSFEV---R 731 Query: 807 ARQRELYLVIERPEELE-VELNGARVETAGSGW-------WRDISFRTIDISGLAAAGRN 858 + ++L+LV+E E L+ + +NG V + D++F ++I+ L G+N Sbjct: 732 KKPQKLFLVVECAENLDRITVNGREVRYERKSCIFNEEQNFLDVNFGKMEITDLVREGKN 791 Query: 859 TLVLRMEFHSSQEIADRLARAKAFEAEGNKLTIDQELESIYLLGDFGVHSGSGFTDGERR 918 T+VL E I + + E ++ T E+E+IYL+GDF + Sbjct: 792 TVVL--EGRKENNITGPGCHTRVKDPENHRPT---EVETIYLVGDFSL------------ 834 Query: 919 AVCTEGPFQLMEPARQVQTGDLTRQGFPFFSGSLRLRQTLELDAARASGAQWFFQ-SPPD 977 V + +++ + D+TR G+PF+ GS L++ E + G ++F + + + Sbjct: 835 -VNVDETRYVIDAPKIPDHRDITRDGYPFYVGSFTLKKIFE--CKKDPGKRYFLKLNGVE 891 Query: 978 AIVTKLFINGAEVRSFLWEPYDADISSFLHSGSNVIELELTGSCRNLLGPHHH--IKGEV 1035 A ++ +NG + W P+ DI+ L +G N ++L LT + NL+ +H + E Sbjct: 892 AASVEVILNGKFLGVLFWRPFMIDITDALRNGKNELQLVLTNTLFNLIEANHKADVLEET 951 Query: 1036 YKVGPDSYKDKPGWTDKDLDKDTHVYQTRYAFVKFGL 1072 ++ P S+ D TD RY + FGL Sbjct: 952 FR-RPKSFIDFEHHTD------------RYILLPFGL 975 >ref|NP_624693.1| possible DNA-binding protein (putative secreted protein) [Streptomyces coelicolor A3(2)] emb|CAB55732.1| possible DNA-binding protein (putative secreted protein) [Streptomyces coelicolor A3(2)] Length = 1134 Score = 135 bits (340), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 117/379 (30%), Positives = 165/379 (43%), Gaps = 32/379 (8%) Query: 179 YTDTLSSMAVKEFIDSTYERYWKQFGEKYGGELSGIFTDEPQFGRGA-----LPWSFELE 233 Y D L V+ F+D Y ++FG +G + G + DEP F LPWS L Sbjct: 427 YVDLLDDEPVELFLDIVPGEYHRRFGHYFGTVVPGFWDDEPFFASAEAHFKRLPWSPAL- 485 Query: 234 DMFIRRHGGNVKEVLPALFLDTMGASR-ARYAYWETVTFMFTQAYAKQIGDWCAGKGWS- 291 D +R G A F D + R AR YW V+ F A+ KQ W +G + Sbjct: 486 DRALRTVGATPGTAYAAAFDDLGRSGRIARGNYWRAVSDRFATAFRKQ-AQWYEKRGVAL 544 Query: 292 ATGHVVDEQELMHQVTSVGDPMAFYEHLQIPGCDWLGR--FVGNDAMVPKQVSSVARQLG 349 T + DE ++ S GD + Q+PG D + G M+P+ SVA Q+G Sbjct: 545 ITNPLYDETAPAKRIPSTGDLHKVNQWAQVPGGDIITAEYVAGEPTMIPRNPVSVAHQMG 604 Query: 350 KKRAITESFGCSGWNVSFADLKRIGEWQFVHGINLLCQHLQGYSLRGLRKRDY-PPSLFY 408 ++RA+ E FG GW V+ + Q G+NL H +L R Y PP Sbjct: 605 RERALLEMFGNMGWQVTPGFVHATVGAQAARGVNLTVLH----ALWTDESRVYFPPPFGP 660 Query: 409 QQPWWSEYKNFNDYFARLSLLLSEGAAQAEVLLLHPVRTA--WT-LQRGGDYSAVIPYHE 465 + PWW + ++ R+ + G + A LL P R A WT R D P E Sbjct: 661 RAPWWWAMRPLAEWIGRV-MEAGRGTSAARTALLQPQRAAEQWTGTDRQQDVDG--PLSE 717 Query: 466 AFARLTRWLCQSLIEHDYGSEGIIA------GHGRVSGGSFIVGEAAYRVVIVPPSVTVD 519 A L R + ++ D EG + H V G +VG AAY +V++P + +D Sbjct: 718 AAYALER----AQVDFDLLHEGALTRDPALLAHAEVRKGRLVVGAAAYDLVVIPRTPVLD 773 Query: 520 RRTAELLREFSAQGGTLIA 538 +LREF GGT+IA Sbjct: 774 ADGVRVLREFVRTGGTVIA 792 >ref|NP_813056.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482] gb|AAO79250.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482] Length = 924 Score = 77.4 bits (189), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 105/442 (23%), Positives = 159/442 (35%), Gaps = 52/442 (11%) Query: 178 YYTDTLSSMAVKEFIDSTYERYWKQFGEKYGGELSGIFTDEPQFGRGALPWSFELEDMFI 237 Y + LS AVK ++ S + R +K Y F D + + W+ + D F Sbjct: 215 YVMNHLSKTAVKNYL-SRFNRAFKSSKTSYPHTF---FNDSYEVYQAD--WTEDFLDQFA 268 Query: 238 RRHGGNVKEVLPALFLDTMGASRARYA---YWETVTFMFTQAYAKQIGDWCAGKGWSATG 294 RR G ++E P FLD +R Y ET++ + + + +Q DW G Sbjct: 269 RRRGYKLEEHFPE-FLDENRPEISRRIVSDYRETISDLLLENFTRQWTDWA-----HKNG 322 Query: 295 HVVDEQELMHQVTSVGDPMAFYEHLQIPGC---------------DWLGRFVGNDAMVPK 339 + Q S + + Y + IP C D L + +D + K Sbjct: 323 SITRNQAH----GSPANLIDVYAAVDIPECEGFGLSQFHIKGLRQDSLTKKNDSDLSMLK 378 Query: 340 QVSSVARQLGKKRAITESFG--CSGWNVSFADLKRIGEWQFVHGINLLCQHLQGYSLRGL 397 SS A GK TE+F + S + K + FV GIN + H YS + Sbjct: 379 YASSAAHIAGKPYTSTETFTWLTEHFRTSLSQCKPDMDLMFVSGINHMFFHGTPYSPK-- 436 Query: 398 RKRDYPPSLFY-------QQPWWSEYKNFNDYFARLSLLLSEGAAQAEVLLLHPVRTAWT 450 + ++P LFY W + +F DY R L G + L+ PV W Sbjct: 437 -EAEWPGWLFYASINMNPTNSIWHDAPSFFDYITRCQSFLQMGKPDNDFLIYLPVYDMWD 495 Query: 451 LQRGGDYSAVIPYHEA-----FARLTRWLCQSLIEHDYGSEGIIAGHGRVSGGSFIVGEA 505 Q G I +H A F + S + DY S+ I G G Sbjct: 496 EQPGRLLLFSI-HHMAKLAPKFIDAIHRINNSGYDGDYISDNFIRSTRFKDGQLITSGGT 554 Query: 506 AYRVVIVPPSVTVDRRTAELLREFSAQGGTLIAFEPYPVLVDGQEDAEFARFMEAAVLPE 565 Y+ ++VP + + L + + QG T++ E YP V G E R L + Sbjct: 555 GYKALVVPAAHLMPNDVLAHLLKLAQQGATIVFLENYPTDVPGYGQLEQKRKTYQQTLQK 614 Query: 566 WSCEALCRAVSAGAGPSLQISG 587 + G I+G Sbjct: 615 LPSVSFSETTVTPVGKGKIITG 636 >dbj|BAD12237.1| alpha-L-rhamnosidase [Sphingomonas paucimobilis] Length = 1117 Score = 58.9 bits (141), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 96/391 (24%), Positives = 148/391 (37%), Gaps = 45/391 (11%) Query: 180 TDTLSSMAVKEFIDSTYERYWKQFGEKYGGE--LSGIFTDEPQFGRGALPWSFELEDMFI 237 D AV+ ++++ Y G ++ G+ + + TD + G A W+ + + F Sbjct: 440 VDKYDPAAVRRYLETYLGLYRDAVGAEWIGKKGIRALLTDSIEVG--ASNWTPRMVEEFR 497 Query: 238 RRHGGNVKEVLPALFLDTMGASRARYAYWETVTFMFTQAYAKQIGDWCAG---KGWSATG 294 R G + LPAL +G++ A+ F Q A + D G K G Sbjct: 498 ARRGYDPVPFLPALTGAVVGSAARSDAFLHD----FRQTLADLLADAHYGTIAKVAHEQG 553 Query: 295 HVVDEQELMHQVTSVGDPMAFYEHLQIPGCDWLGRFVGNDAMVP------KQVSSVARQL 348 +V + L + +GD +A H +P L + A P K +SVA Sbjct: 554 LIVYGEALENGRPVLGDDLAMRAHADVPMAA-LWTYNRGSAPRPTLIGDMKGAASVAHIY 612 Query: 349 GKKRAITESFGC--SGWNVSFADLKRIGEWQFVHGINLLCQHLQGY-----SLRGLRKRD 401 G+ ES S W + ADLKR+ + +FV G+N H + L GL Sbjct: 613 GQNIVSAESMTAAFSPWAFAPADLKRVIDLEFVSGVNRPIVHTSVHQPVDDKLPGLSLAI 672 Query: 402 YPPSLFYQQPWWSEYKNFNDYFARLSLLLSEGAAQAEVLLLHPVRTAWTLQRGGDYSAVI 461 + W + + DY AR LL +G A++ H G D Sbjct: 673 FGQYFNRHDSWAEMARPWVDYMARTGFLLQQGRDHADIAWFH----------GEDMPVTA 722 Query: 462 PY-HEAFARLTRWLCQSLIEHDYGSEGIIAGHGRVSGGSFIV-GEAAYRVVIVPPSVTV- 518 + H A L R + D I+A +V GG + G A YR + + S V Sbjct: 723 LFEHGEPAGLPRRHGYDFVNAD-----ILAKVLKVEGGELVAPGGARYRALYLGGSSRVM 777 Query: 519 DRRTAELLREFSAQGGTLIAFEP--YPVLVD 547 T + + + QG T+I P P L D Sbjct: 778 TLPTLRRIAQLAEQGATVIGTAPERSPALQD 808 >gb|EAD21940.1| unknown [environmental sequence] Length = 181 Score = 58.2 bits (139), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 19/162 (11%) Query: 181 DTLSSMAVKEFIDSTYERYWKQFGEKYGGELSGIFTDEPQF-------GRGALPWSFELE 233 D L+ AV F+ T++RY++ +G + +FTDEP P++ E Sbjct: 31 DILNPEAVACFLRLTHDRYFETLEPFFGDTIIAMFTDEPNVLGRGGSRRGQGKPYTPGFE 90 Query: 234 DMFIRRHGGNVKEVLPALFLDTMGASRA-RYAYWETVTFMFTQAYAKQIGDWCAGKGWSA 292 D R G + + LPAL+ D + A R+ Y E V + + WCA G + Sbjct: 91 DWIADRWGEDPRPWLPALWEDYGEETEAFRHRYSEAVYARLVETFYNAQSKWCAEHGIAL 150 Query: 293 TGHVVDEQELMHQVTSVGDPMAFYEHLQIPGCDWLGRFVGND 334 TGH + EL P+ + Q+PG D + R+V D Sbjct: 151 TGHPAESNEL--------SPLRLF---QMPGQDMVWRYVEPD 181 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.137 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,621,964,049 Number of extensions: 68648712 Number of successful extensions: 134375 Number of sequences better than 1.0e-05: 5 Number of HSP's gapped: 134365 Number of HSP's successfully gapped: 6 Length of query: 1083 Length of database: 757,237,578 Length adjustment: 136 Effective length of query: 947 Effective length of database: 387,984,114 Effective search space: 367420955958 Effective search space used: 367420955958 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)