BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0030.p (1606 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_389600.1| polyketide synthase of type I [Bacillus subtili... 530 e-148 emb|CAB13603.2| polyketide synthase [Bacillus subtilis subsp. su... 529 e-148 emb|CAB13602.2| polyketide synthase of type I [Bacillus subtilis... 529 e-148 pir||T44806 mycosubtilin synthetase chain mycA [imported] - Baci... 513 e-143 dbj|BAB69698.1| iturin A synthetase A [Bacillus subtilis] 508 e-142 >ref|NP_389600.1| polyketide synthase of type I [Bacillus subtilis] sp|Q05470|PKSL_BACSU Putative polyketide synthase pksL (PKS) pir||PN0637 polyketide synthase pksL - Bacillus subtilis emb|CAA78479.1| Hypothetical polyketide synthase [Bacillus subtilis] gb|AAA85145.1| polyketide synthase Length = 4427 Score = 530 bits (1366), Expect = e-148, Method: Compositional matrix adjust. Identities = 469/1611 (29%), Positives = 731/1611 (45%), Gaps = 275/1611 (17%) Query: 40 DIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDTQY 99 DIAIIG++G++ +A ++ FW L +GK+C+ EIP R D R G SP Sbjct: 324 DIAIIGLAGRYPKAANIHEFWNNLKEGKDCVSEIPESR-WDWQR---LEGITSPSGKDIS 379 Query: 100 TRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLC---GSKT 156 ++D+ D FD FF I P EA+ +DP++RLFLE+ W T+EDAGY L G Sbjct: 380 KWGGFIDDPDCFDPQFFRITPREAETMDPQERLFLETCWETIEDAGYTPKTLAKPKGRNK 439 Query: 157 GVYVGLSSDGXXXXEYFKLIEQGDPSLIGL--STAGNIKSV------IAGRLAYILDFKG 208 +VG+ F + D +L+G ++A N+ + IA R++Y +F G Sbjct: 440 RQHVGV----------FAGVMHKDYTLVGAEEASAENVFPLSLNYAQIANRVSYFCNFHG 489 Query: 209 PSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGI---TSS 265 PSM +DT CSSSL A+H+A ++I++ EC+ AL GGVN+ + P + G+ S+ Sbjct: 490 PSMAVDTVCSSSLTAVHLALESIRHGECDVALAGGVNLSLHPN----KYMTYGVWDMFST 545 Query: 266 DSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPN 325 D RTF DG EG+ AVL+KPL +A D D IYAVIKGSAVN G+ GI+ P+ Sbjct: 546 DGHCRTFGKDGDGYVPAEGIGAVLLKPLRQAEEDGDRIYAVIKGSAVNHVGTVSGISVPS 605 Query: 326 MTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIG 385 +Q ++I ++ IDP+T++Y EAHGTGT LGDPIE+ + +AF ++T +QFC+IG Sbjct: 606 PVSQADLIETCLEKTGIDPRTISYVEAHGTGTSLGDPIEIQGLVKAFRQYTQDRQFCSIG 665 Query: 386 SVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK 445 SVK+NIGH +S AG++GL K + + ++K+ PSLH + N + F SP YV +T WK Sbjct: 666 SVKSNIGHAESAAGISGLSKVALQLHHQKLVPSLHSEELNPYVDFEKSPFYVQHETETWK 725 Query: 446 -------GYDGVY--RCGISSFGLSGTNAHVVLEGPPPLEQRQD-----EVPANHIFTVS 491 G D Y R GISSFG +G+NAH++LE P QD + + + +S Sbjct: 726 QPVIKENGEDVPYPRRAGISSFGATGSNAHIILEEHIPQAAEQDVSLSSDSDISAVIPLS 785 Query: 492 AKTEASLEKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKL 551 A+ + L L+FL ++I DL YT+ GR P + R++ + S +EL +LK Sbjct: 786 ARNQERLRVYAKRLLDFL--HDGIQIRDLAYTLQVGREPMEERVSFLASGIQELSDQLKA 843 Query: 552 LARNGAGTYKAEDIYYRKLERNLKFIGKSMTGSGGLTESSHKSIADLQL--LCGAYCDGA 609 G + + ++ R + ES HK + +L + + +G+ Sbjct: 844 FIE---GRKAIQHCWKGRVSRG--------SEPSRPAESVHKLLEQRKLDQIAEQWANGS 892 Query: 610 DMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELPESR--RSLTAARTRHPLLQERAVSSLN 667 +D++ +Y +++S PTY FE+ R WV E + RS HPLL + VS ++ Sbjct: 893 GVDWKLLYEGSKPKRISLPTYPFERVRYWVPKAEKKTDRSKQERHILHPLLHQN-VSDIS 951 Query: 668 LEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDMAKEIGTRHFGEARDIILSDVSFLNL 727 + S ++F+ L +H + V+PG A L+M + R A D + N+ Sbjct: 952 GVRFRSAFTGREFF-LKDHVIKGEHVLPGAALLEMVRAAVER---AAADQFPTGFRLRNI 1007 Query: 728 LKVEKDEVKEIHTIVNIK-----DDALKFTVASRASAAEEW-IKHAEAWIGRKERQPHTT 781 + V V E ++++ + + F + +AEE I + + E + Sbjct: 1008 VWVRPFAVTEQQKDIDVRLYPEENGEITFEICRDPESAEESPIVYGQGSAVLCEAGENPV 1067 Query: 782 YDIETLKTTYDSVYAIRRNQSWPVIEESSYTSVQYVEDTNRPESIINVGGRWKCTNAIYR 841 +IE LK +Y+ R S P +YT E I+ G + +++Y Sbjct: 1068 INIEELKASYNG-----RTLS-PFDCYEAYT-----------EMGIHYGDSHRAIDSLYA 1110 Query: 842 SKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVNA------GTFTINED--TYLPYYYKE 893 + GVL +L + ++ + + LHP+M+D A A G T ED LP+ ++ Sbjct: 1111 GENGVLVKLTMPPVISDTEDHYILHPSMIDSAFQASIGLRLGGATSLEDRKAMLPFAIQD 1170 Query: 894 FRIFGPTPKKFYSYIT--KKNNENEETGKFDLLLLNEQGEVFGEISSYIVKRVHSFTPLE 951 RIF ++ IT + + + K D+ L NE+G+V ++SY + + T E Sbjct: 1171 VRIFKGCEASMWARITYSEGSTAGDRMQKLDIDLCNEEGQVCVRLTSYSARVLE--TDQE 1228 Query: 952 QPSAQKSIYHKLGWVEKNEYKLLRRSEANGGILLFHNQAKLAGEIIASLRQAGKKVIEAI 1011 P SEAN +L H + A E + KV+ Sbjct: 1229 GP-----------------------SEANDTLLFEHIWEERAAERQELIEYDTYKVV--- 1262 Query: 1012 PGQAFSERGEQAYSLGGR---------QEDYDKLFAAIELQKISQIIHLMTIQDHSAEGG 1062 + GEQ SL E D+ F +Q +I LM HS GG Sbjct: 1263 ----VCDVGEQMESLQNHLDCTVLQHDTETIDERFEGYAIQLFEEIKQLM----HSKTGG 1314 Query: 1063 HQQLEYNLKLGLDSLFYLSQSIMKHPNDPVELVLFAEHVHRISGSETAVNPHHAAFFGLG 1122 H ++ + LD LS GL Sbjct: 1315 HTFIQVAVP-ALDEPQLLS-----------------------------------GLTGLL 1338 Query: 1123 KVLGKEYSKLNVRCIDIDGETRAAECIREINGEKQVEL---VGYREGRPYVQELQAVPVP 1179 K E KL + I+I+ A E + ++ + + +G+ +V + + V Sbjct: 1339 KTAELENPKLTGQLIEIETGMSAGELFEILEENRRYPRDTHIRHWQGKRFVSKWKEVSGE 1398 Query: 1180 ALPDQQAEIKKDGVYIITXXXXXXXXEVARYLSSLAK-VNLILVGRSGLSHPIDPGSKNH 1238 L K GVY+IT A +++ +IL GRS P+D K Sbjct: 1399 HL-SADMPWKDKGVYLITGGAGGLGFIFATEIANQTNDAVVILTGRS----PLDERKKKK 1453 Query: 1239 TRTEIMNHIRANGSNVDCY-QADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEGFIF 1297 + I+A Y QAD+AD++ + A+L + + Y ++GI H AG+ + FI Sbjct: 1454 LKALQKLGIQA------IYRQADLADKQTVDALLKETQNVYGDLDGIIHSAGLIKDNFIM 1507 Query: 1298 RKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAYLDS 1357 +K K V PK+ G LD+ T + LDFF++FSS GS GQADY ANA++++ Sbjct: 1508 KKKKEEVQTVLAPKVAGLIHLDEATKDIPLDFFILFSSGAGAVGSAGQADYAMANAFMNA 1567 Query: 1358 YAEYRS----LIKPEQKTLTINWCGWKDTGMLADYRNK--LGKEAGTEENQNEQGFKNI- 1410 ++EYR+ L K KTL++ W WKD GM D L +E G + ++G + + Sbjct: 1568 FSEYRNGQAELHKRYGKTLSVCWPLWKDGGMQIDAETARMLKRETGMVAMETDRGIQALY 1627 Query: 1411 --------------GTREAIEAL---------------NVVLNKEISKV-IIGELDDKVF 1440 G + I A LN+E K +IGE+D+++ Sbjct: 1628 HGWTSGKPQVLVASGVTDRIRAFLHETGHGKGQSHNIKKSSLNQEAEKADMIGEIDEEIL 1687 Query: 1441 GLYKDQITFSLAPEIAARIRPTRPKAPGHTGLPPVPMEHRDYSGIESAIVKAWVKVLGLE 1500 R KA + + + S+++K L Sbjct: 1688 ----------------------REKAENY------------FKQVLSSVIK-----LPAG 1708 Query: 1501 QININDKFYDLGGDSISAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYI 1551 QI+ D G DSI +++ ++ KVF SL + F Y I ++ Y Sbjct: 1709 QIDAEAPLEDYGIDSIMIMHVTGQLEKVFGSL-SKTLFFEYQDIRSLTRYF 1758 Score = 400 bits (1029), Expect = e-109, Method: Compositional matrix adjust. Identities = 245/636 (38%), Positives = 351/636 (55%), Gaps = 46/636 (7%) Query: 33 VKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKS 92 V+ +IAIIG+SG++ +A+++ WE L G++CI EIP R D L + K Sbjct: 1810 VREKETEEIAIIGISGRYPQADNIDELWEKLRDGRDCITEIPADR---WDHSLYYDEDKD 1866 Query: 93 PHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLC 152 T ++ ++DKFD FF I P EAKL+DP++RLFL+ + T+EDAGY L Sbjct: 1867 KPGKTYSKWGGFMKDVDKFDPQFFHISPREAKLMDPQERLFLQCVYETMEDAGYTREHL- 1925 Query: 153 GSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLI---GLSTAGNIKSVIAGRLAYILDFKGP 209 G K +G S Y + G + L+ GN S IA R++Y DF GP Sbjct: 1926 GRKRDAELGGSVGVYVGVMYEEYQLYGAQEQVRGRSLALTGN-PSSIANRVSYYFDFHGP 1984 Query: 210 SMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIG---ITSSD 266 S+ +DT CSSSL A+H+ACQ+++ ECEAA GGVN+ I P L +G SS Sbjct: 1985 SIALDTMCSSSLTAIHLACQSLQRGECEAAFAGGVNVSIHPN----KYLMLGQNKFMSSK 2040 Query: 267 SSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNM 326 +F DG GEGV AVL+KPL KA+ D DHIY +IKG+A+N G + G + PN Sbjct: 2041 GRCESFGQGGDGYVPGEGVGAVLLKPLSKAVEDGDHIYGIIKGTAINHGGKTNGYSVPNP 2100 Query: 327 TAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGS 386 AQ +VI A+ EA++DP+TV+Y EAHGTGT LGDPIE+ + + F + TD KQFCAIGS Sbjct: 2101 NAQADVIKKAFVEAKVDPRTVSYIEAHGTGTSLGDPIEITGLSKVFTQETDDKQFCAIGS 2160 Query: 387 VKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK- 445 K+NIGH +S AG+AG+ K ++ ++YR + PSLH V N NI F +SP V + +WK Sbjct: 2161 AKSNIGHCESAAGIAGVTKVLLQMKYRHVAPSLHSNVLNPNIDFLNSPFKVQQELEEWKR 2220 Query: 446 ------GYD-GVYR-CGISSFGLSGTNAHVVLE--GPPPLEQRQDEVPANHIFTVSAKTE 495 G D + R G+SSFG G NAH+++E P P+E+R + +SAK E Sbjct: 2221 PIISVNGKDIELPRIAGVSSFGAGGVNAHILIEEYAPEPVEERLPARKQPAVIVLSAKNE 2280 Query: 496 ASLEKLILNYLEFLGKEQELRISDL---CYTVNTGRLPNQCRIAMIVSSTEELIRKLKLL 552 L+K L + +EQ +DL YT+ GR + R+A + + +EL KL Sbjct: 2281 ERLQKRPERLLHAI-REQTYVEADLHRIAYTLQVGREAMKERLAFVAETMQELEEKLYEC 2339 Query: 553 ARNGAGTYKAEDIYYRKLERNLKFIGK-------SMTGSGGLTESSHKSIADLQLLCGAY 605 +GT E +Y +++ N + I S T L + + + DL + Sbjct: 2340 I---SGTENREYVYRGQVKSNKEAIAAFAADEDMSKTIEAWLQKGKYAKVLDL------W 2390 Query: 606 CDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVEL 641 G +D+ +Y+ R++S P Y F + R W+++ Sbjct: 2391 VRGLRIDWSTLYQDQKPRRISLPAYPFARDRYWIDV 2426 Score = 383 bits (984), Expect = e-104, Method: Compositional matrix adjust. Identities = 233/640 (36%), Positives = 360/640 (56%), Gaps = 44/640 (6%) Query: 38 ESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDT 97 E IAI+GMSG++ A ++R +W+ L+ + IR+IP R D D+Y + K + Sbjct: 2762 EDAIAIVGMSGRYPGARNVREYWDNLVHARNAIRDIPTSR-WDVDKYYDPVLNK---KGK 2817 Query: 98 QYTR-IAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLCGSKT 156 Y + + LD+I+ FD FF I P+EA+L+DP+ R+FL+ + EDAGY L K Sbjct: 2818 VYCKSMGMLDDIEHFDPLFFNIPPSEAELMDPQHRIFLQEGYKAFEDAGYNARTLNEKKC 2877 Query: 157 GVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILDFKGPSMMIDTA 216 GVY+G+ S+ EY ++ + + + GN ++ A R+ Y L+ KGP++ IDTA Sbjct: 2878 GVYLGIMSN-----EYGVMLNRQSRA----NATGNSFAIAAARIPYFLNLKGPAIPIDTA 2928 Query: 217 CSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGITSSDSSIRTFDDQA 276 CSSSLV H+A QA+ N E + ALVGGV++ + P++ + G+ S D + FD+ A Sbjct: 2929 CSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYM-SMCEAGMLSPDGQCKAFDNGA 2987 Query: 277 DGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMTAQENVITDA 336 +G GEG A+++K L A DRDHIY +I GS +NQDG + GITAP+ +Q ++ D Sbjct: 2988 NGFVPGEGAGALVLKRLKDAEADRDHIYGIIIGSGINQDGKTNGITAPSAKSQMDLERDI 3047 Query: 337 WKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSVKTNIGHLDS 396 ++ I P++++Y E HGTGTK GDPIE+ A+ F TD+KQFCAIGSVK+NIGH + Sbjct: 3048 YETYGIHPESISYVEMHGTGTKQGDPIELEALSTVFQEKTDKKQFCAIGSVKSNIGHTSA 3107 Query: 397 LAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWKGYDG-VYRCGI 455 AG+AG+ K ++ + ++ + P+L+F PN + +F SP+YVN + W+ DG R + Sbjct: 3108 AAGVAGVQKVLLCMNHKTLVPTLNFTTPNEHFEFEHSPLYVNTELKPWETADGKPRRACV 3167 Query: 456 SSFGLSGTNAHVVLEGPPPLEQRQDEVPANH---IFTVSAKTEASLEKLILNYLEFLGKE 512 SSFG SGTNAH+V+E P E+R D + H +F +SAK E L+ +F+ Sbjct: 3168 SSFGYSGTNAHIVIEEYQP-EKRNDRLTKQHRSALFVLSAKKEKQLKAYAEAMKDFVTSN 3226 Query: 513 QELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKL-KLLARNGAGTYKAEDIYYRKLE 571 +++ + D+ YT+ TGR R+A + S E LI+ L LA + A + +K E Sbjct: 3227 EDIDLEDMAYTLQTGREAMDYRMAFLADSREMLIKALDDYLAEMPNASIFAAHVKTKKSE 3286 Query: 572 RNLKFIGKSMTGSGGLTESSHKSIADLQL---------LCGAYCDGADMDFEGIYRQLDC 622 L E+ H + A LQ + + G +D+ +Y + Sbjct: 3287 IK-------------LFETDHDAKALLQTWIEKKRLEKVAELWVKGLQIDWNKLYGEYTP 3333 Query: 623 RKVSWPTYAFEQKRLWVELPESR-RSLTAARTRHPLLQER 661 R++S P Y F ++ W+ E ++ A + L+ +R Sbjct: 3334 RRISLPAYPFAEEYYWLPTQEGEPETIATAMPQFELMPKR 3373 Score = 228 bits (580), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 141/446 (31%), Positives = 239/446 (53%), Gaps = 58/446 (13%) Query: 40 DIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDTQY 99 DIAIIG+S +F A L +W+++ G+ I +P R ++ ++G Sbjct: 3973 DIAIIGLSCRFPGAETLEEYWDLIRDGRSAIAPVPPERFGNSSS--NYAG---------- 4020 Query: 100 TRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLCGSKTGVY 159 +DE+++FD FF + ++ + +DP+ LE + AGY ++ G + GVY Sbjct: 4021 ----LIDEMNRFDHDFFMMSESDVRAMDPQALAVLEESLKLWYHAGYTEKEVKGMRAGVY 4076 Query: 160 VGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNI-----KSVIAGRLAYILDFKGPSMMID 214 +G S Q P LS A N ++ +A ++ D KGPS+++D Sbjct: 4077 IGGRS-------------QHKPDPASLSKAKNPIVAGGQNYLAANISQFFDLKGPSILLD 4123 Query: 215 TACSSSLVALHVACQAIKNHECEAALVGGVNI------KIFPKTEEENNLNIGITSSDSS 268 TACSS+LV L++A QA+++ + EAA+VGGV++ ++F + G+ S Sbjct: 4124 TACSSALVGLNMAIQALRSGDIEAAVVGGVSLLDADAHRMFHER--------GLLCDKPS 4175 Query: 269 IRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMTA 328 FD +ADG GEGV VL+K +++A+ D D IYAVIK +A+N DG + G ++PN+ A Sbjct: 4176 FHIFDKRADGVILGEGVGMVLVKTVNQAVEDGDSIYAVIKAAAINNDGRTAGPSSPNLEA 4235 Query: 329 QENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSVK 388 Q++V+ A +++ + ++Y EA+G+G+ + D +E+ AI + ++ K +GSVK Sbjct: 4236 QKDVMLSALEKSGKKTEEISYLEANGSGSAVTDLLELKAIQSIYR--SESKAPLGLGSVK 4293 Query: 389 TNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQF---SSSPVYVNDQTTDWK 445 NIGH G+A LIK + +++R++ P F N N+ + + +Y + +WK Sbjct: 4294 PNIGHPLCAEGIASLIKVALMLKHRQLVP---FLSGNENMPYFDIEKTDLYFSRSQAEWK 4350 Query: 446 GYDGVYRCGISSFGLSGTNAHVVLEG 471 + I+ F GTNAH+++EG Sbjct: 4351 --ETTPAAAINCFADGGTNAHLIIEG 4374 Score = 116 bits (291), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 120/461 (26%), Positives = 200/461 (43%), Gaps = 54/461 (11%) Query: 1116 AAFFGLGKVLGKEYSKLNVRCIDIDGETRAAECIREINGE---KQVEL-VGYREGRPYVQ 1171 A+ GL ++L EYS L R D++ E E R I E K E V YR G+ Y Sbjct: 3495 ASRAGLYRMLQSEYSHLTSRHADMECEASHEELARLIAVEYYAKSTESEVCYRNGQRYRA 3554 Query: 1172 ELQAVPV-PALPDQQAEIKKDGVYIITXXXXXXXXEVARYLSSLAKVN-LILVGRSGLSH 1229 L P AL +Q D V +IT AR+ V L+L+GR L Sbjct: 3555 YLTEQPAEAALSHKQVSFSTDKVLLITGGTRGLGLLCARHFVKTYGVKRLVLIGREELP- 3613 Query: 1230 PIDPG-----SKNHTRTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGI 1284 P D S + + + + G+ V D+ D ++ L + + +I G+ Sbjct: 3614 PRDQWNSVKISSLAEKIKAVQELEDMGAQVQVLSLDLTDRVAVEQSLKTIHETMGAIGGV 3673 Query: 1285 FHCAGVAGE---GFIFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSG 1341 HCAG+ + FI RK +V PK++G + L L ++ L FF +FSS+++ Sbjct: 3674 IHCAGMVNKQNPAFI-RKSLEEIGQVLEPKVEGLQTLFDLLQDEPLAFFTLFSSVSAAIP 3732 Query: 1342 SM--GQADYTAANAYLDSYAEYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTE 1399 ++ GQADY ANA++D +AE P ++I W WK+TG L + R+K ++ G Sbjct: 3733 ALAAGQADYAMANAFMDYFAEAHQDKCP---IVSIQWPNWKETG-LGEVRSKALEQTGLI 3788 Query: 1400 ENQNEQGFKNIGTREAIEALNVVLNKEISKVIIGELDDKVFGLYKDQITFSLAPEIAARI 1459 N++G ++ L+ +L+ V++ + D ++K + + A Sbjct: 3789 SLTNDEG---------LQLLDQILSDRQYAVVLPAVPDT--NVWKPDKLMQPSLPVEALS 3837 Query: 1460 RPTRPKAPGHTGLPPVPMEHRDYSGIESAIVKAWVKVLGLEQINI-------NDKFYDLG 1512 P + L P ++ W+ L +++ I ++ F + G Sbjct: 3838 HPETKEQTSTRNLFPETVD--------------WLVTLFSDELKIAAEDFETDEPFQEYG 3883 Query: 1513 GDSISAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYIQS 1553 DSI LV+++ + ID S +F YP+I + ++ S Sbjct: 3884 IDSIILAQLVQQMNQQLNGDIDPSILFEYPTIESFAHWLIS 3924 >emb|CAB13603.2| polyketide synthase [Bacillus subtilis subsp. subtilis str. 168] Length = 4262 Score = 529 bits (1363), Expect = e-148, Method: Compositional matrix adjust. Identities = 429/1490 (28%), Positives = 713/1490 (47%), Gaps = 162/1490 (10%) Query: 5 FISLKELKASAFTASTLESEDRLLRDS-------AVKPMSESDIAIIGMSGKFGEANDLR 57 F ++ EL A ++ D +R S P DIAIIGM+G++ +A +++ Sbjct: 353 FTTIAELAAHLADHYSIGEADDAVRQSPSPIDGVTSSPEIGEDIAIIGMAGRYPKAKNIQ 412 Query: 58 AFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFG 117 FWE L G +CI EIP R + E G SP +++E D FD FF Sbjct: 413 EFWEQLKAGTDCITEIPNSRW----EWKESDGLDSPAGKPLSKWGGFIEEADCFDPQFFR 468 Query: 118 ILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLCGSK-------TGVYVGLSSDGXXXX 170 I P EA+++DP++RLFLE+ W +EDAGY + + GV+ G+ Sbjct: 469 ISPREAEMMDPQERLFLETCWEAIEDAGYTPETIASPQGENKRQHVGVFAGVMHKDYSLI 528 Query: 171 EYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILDFKGPSMMIDTACSSSLVALHVACQA 230 L E +P + L+ A IA R++Y +F GPSM +DT CSSSL A+H+A ++ Sbjct: 529 GAEALSEH-NPFPLSLNYAQ-----IANRVSYYCNFHGPSMAVDTVCSSSLTAVHLAIES 582 Query: 231 IKNHECEAALVGGVNIKIFPKTEEENNLNIGITSSDSSIRTFDDQADGTNSGEGVAAVLI 290 I+N ECEAAL GGVN+ + P ++G+ SSD TF DG SGEGV VL+ Sbjct: 583 IRNGECEAALAGGVNLSLHPAKYISYG-SVGMHSSDGYCHTFGKGGDGYVSGEGVGTVLL 641 Query: 291 KPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMTAQENVITDAWKEARIDPQTVTYW 350 KPL KA +D D IYAVIKGSA+N G GIT P+ AQ +VI ++ IDP+T++Y Sbjct: 642 KPLRKAEQDGDRIYAVIKGSAINHVGKVSGITVPSPVAQADVIEACLEKTGIDPRTISYV 701 Query: 351 EAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSVKTNIGHLDSLAGLAGLIKAVMAI 410 EAHGTGT LGDPIEV + +AF+R T KQFC+IGSVK+NIGH ++ AG++GL K V+ + Sbjct: 702 EAHGTGTSLGDPIEVQGLVKAFSRNTQDKQFCSIGSVKSNIGHAEAAAGISGLTKTVLQL 761 Query: 411 QYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK-------GYDGVY--RCGISSFGLS 461 ++ + PSLH + N ++ +P +V +T +W+ G D Y R G+SSFG S Sbjct: 762 HHKTLVPSLHSEELNPYLKLDQTPFFVQHETKEWEQPSFTENGVDVTYPRRAGLSSFGAS 821 Query: 462 GTNAHVVLEGPPPLEQRQDEVPANH---IFTVSAKTEASLEKLILNYLEFLGKEQELRIS 518 G+NAH++LE P E + + + + +SA+ + L+ L L+FL +++ + Sbjct: 822 GSNAHLILEEYIPAESHSETILTKNEEIVIPLSARNKDRLQAYALKLLDFLS--EDVNLL 879 Query: 519 DLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLARNGAGTYKAEDIYYRKLERNLKFIG 578 L YT+ GR+ + R A IV ++L KL+ A G + E + + + N Sbjct: 880 ALAYTMQAGRVEMEERAAFIVKDIKDLTAKLRAFAN---GEEEIEGCWTGRAKEN----- 931 Query: 579 KSMTGSGGLTESSHKSIADLQL--LCGAYCDGADMDFEGIYRQLDCRKVSWPTYAFEQKR 636 + G + ++ I D ++ + A+ G + ++ +Y K+S PTY F ++R Sbjct: 932 QEAAGLASVNALNNNLIRDSEMMEMAKAWVQGKRVTWDDLYGDRKPLKISVPTYPFARER 991 Query: 637 LWVELPESRRSLTAARTRHPLLQERAVSSLNLEVYVSYLNVQDFWVLNEHQVNDACVIPG 696 W+ +PE + S T HPL+ R S + + S +F+ L++H V ++PG Sbjct: 992 YWISVPEMKTS-TVNHILHPLVH-RNTSDFTEQRFSSVFTGTEFF-LSDHVVQGQKILPG 1048 Query: 697 TAYLDMAKEIGTRHF----GEARDIILSDVSFLNLLKVEKDEVKEIHTIVNIKDDA-LKF 751 AYL+MA+E + GE R + L D+ ++ + +E E KEIH + +D+ + F Sbjct: 1049 VAYLEMAREAAEKAAGDLDGEQRVVSLKDIVWVRPITIE-SEPKEIHIGLFPEDNGDISF 1107 Query: 752 TVASRASAAEEWIK-HAEAWIGRKERQPHTTYDIETLKT--TYDSVYAIRRNQSWPVIEE 808 + S + EE + H + + + ++ +++T + D+V + E Sbjct: 1108 DIYSSSEHKEEALTIHCQGRAVISDEAETSILNLSSIQTECSLDTVTS-----------E 1156 Query: 809 SSYTSVQYVEDTNRPESIINVGGRWKCTNAIYRSKEGVLCELEIQAEYAEDLEQFYLHPA 868 Y + + + ++ G ++ +Y K+ +L ++ + A D + F LHP+ Sbjct: 1157 QCYAAFRKIG--------LDYGEGYQGIEKVYVGKDQLLAKISLPAFLKNDKQHFALHPS 1208 Query: 869 MMDCAVNAGT-FTIN--------EDTYLPYYYKEFRIFGPTPKKFYSYITKKNNENEETG 919 +MD A +A F ++ + LP+ +E IF P P+K +SYI ++ E Sbjct: 1209 LMDSAFHATVGFIVSSVNAAGQAQTLSLPFALQEVDIFSPCPEKIWSYIRYSSDSKAENK 1268 Query: 920 --KFDLLLLNEQGEVFGEISSYIVKRVHSFTPLEQPSAQKSIYHKLGWVEKNEYKLLRRS 977 K+D+ L +E G V + ++ + EQ S +LL S Sbjct: 1269 VRKYDIDLCDENGRVCVRMKGASMRALDG----EQHSKP---------------QLLTDS 1309 Query: 978 EANGGILLFHNQAKLAGEIIASLRQAGKKVIEAIPGQAFSERG------EQAYSLGGRQE 1031 + G ++ ++ E + AGK+ + + G A ++R Q + R Sbjct: 1310 QLTGHTVMIPVWEPVSLEAEDNASFAGKRAV--LCGAAEADRTFIKHHYPQISFVDIRPA 1367 Query: 1032 DYDKLFAAIELQKISQIIHLMTI--QDHSAEGGHQQLEYNLKLGLDSLFYLSQSIMK--H 1087 D D A +LQ I H++ I + G Q E L LF L ++ ++ + Sbjct: 1368 D-DIEAIADKLQAYGSIDHVLWIAPSHRGSIGSDGQEEAVLH-----LFKLVKACLQLGY 1421 Query: 1088 PNDPVELVLFAEHVHRISGSETAVNPHHAAFFGLGKVLGKEYSKLNVRCIDID-GETRAA 1146 +E L ++ E AV P HA+ GL + KEY +R +D++ G T Sbjct: 1422 GEKQLEWSLVTVQAQPVTQHE-AVQPAHASIHGLAGTMAKEYPHWKIRLLDLEKGCTWPV 1480 Query: 1147 ECIREINGEKQVELVGYREGRPYVQELQAVPVPALPDQQAEIKKDGVYIITXXXXXXXXE 1206 + + ++ YR + + Q+L +P + +K GVY++ Sbjct: 1481 NHMFALPADRLGHAWAYRNQQWHQQQL--IPYRSSLSGDTLYRKGGVYVVIGGAGYIGEA 1538 Query: 1207 VARYLSSLAKVNLILVGRSGLSHPIDPGSKNHTRTEIMNHIRANGSNVDCYQADVADERE 1266 + Y+ + ++ +GRS L+ I SK ++ + A G AD AD+ Sbjct: 1539 WSEYMIRRYQAQIVWIGRSQLNAAIQ--SK-------IDRLSALGPEPFYIAADAADKHS 1589 Query: 1267 MQAMLAQLRQRYTSINGIFHCAGVAGEGFIFRKDKAAFDRVTRPKIQGTRILDKLTAEDK 1326 +Q Q+++R+ I+GI H A V E + + F KI + + ++ ++ Sbjct: 1590 LQQAYEQVKKRHPHIHGIVHSAMVLFEQSLEKMKPEEFTAGLAAKIDVSIRMAQVFRQEN 1649 Query: 1327 LDFFVMFSSITSLSGSMGQADYTAANAYLDSYAEY--RSLIKPEQKTLTINWCGWKDTGM 1384 +DF + FSS+ + ++ Q+ Y + + D++A +S P + +NW W ++ Sbjct: 1650 VDFVLFFSSLVAHIKNVKQSHYASGCTFADAFAHQLSQSWACPVK---VMNWGYWGNS-- 1704 Query: 1385 LADYRNKLGKEAGTEEN----QNEQGFKNIGTREAIEALNVVLNKEISKV 1430 EA +E+ N+ G I EA++AL +L+ +S+ Sbjct: 1705 ----------EAAEDEHYVQLMNQIGLGLIEPAEAMKALEALLSGPVSQT 1744 Score = 384 bits (985), Expect = e-104, Method: Compositional matrix adjust. Identities = 230/629 (36%), Positives = 352/629 (55%), Gaps = 57/629 (9%) Query: 29 RDSAVKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFS 88 +++ ++ D+A+IG+SG++ +A FW L +G+ CI EIP R D Y + Sbjct: 2310 KETPTNTLASRDVAVIGISGRYPQAETAEDFWNNLKEGRNCIEEIPKDR-WDWKAYYDKE 2368 Query: 89 GGKSPHEDTQYTRIA-YLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYG 147 GK E + YT+ ++ ++DKFD FF I P EA+ +DP++RLFL++A++++EDAGY Sbjct: 2369 KGK---EGSIYTKWGGFIKDMDKFDPLFFQISPLEAERMDPQERLFLQTAYASIEDAGYT 2425 Query: 148 GGKLCGS-KTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILDF 206 LC S K GV+ G+ + + P+ G + IA R++Y+L+F Sbjct: 2426 PDSLCSSRKIGVFAGV-------------MNKNYPTGYGYWS-------IANRISYLLNF 2465 Query: 207 KGPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGITSSD 266 +GPS+ +DTACSSSL A+H+A ++I + + A+ GGVN+ + P +N + + S+ Sbjct: 2466 QGPSLAVDTACSSSLTAIHLALESIYSGSSDCAIAGGVNLVVDP-VHYQNLSVMNMLSAS 2524 Query: 267 SSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNM 326 + ++F D ADG GEGV A+++KPL +AI D DHIY VIK SA+N G + G T PN Sbjct: 2525 DTCKSFGDDADGFVDGEGVGAIVLKPLQQAIADGDHIYGVIKASAINSGGKTNGYTVPNP 2584 Query: 327 TAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGS 386 AQ VI +A + A I +T++Y EAHGTGT LGDPIE+ + +AF + T KQFCAIGS Sbjct: 2585 HAQAQVIKEAIERADIPARTISYLEAHGTGTALGDPIEIAGLTKAFEKDTQEKQFCAIGS 2644 Query: 387 VKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK- 445 K+NIGH +S AG+AGL K + +Y +I PSLH + N NI+FS +P V Q +WK Sbjct: 2645 SKSNIGHCESAAGIAGLTKILFQFKYGQIAPSLHAQRLNPNIEFSHTPFVVQQQLGEWKR 2704 Query: 446 ----GYDGVYRCGISSFGLSGTNAHVVLEGPPPLEQRQDEVPANH---IFTVSAKTEASL 498 G + R G+SSFG G+NAH++LE P Q P +H + +SAK L Sbjct: 2705 PVIGGQEVPRRAGLSSFGAGGSNAHIILEEYIPRTGAQ--TPKDHPPALIVLSAKNMERL 2762 Query: 499 EKLILNYLEFLGKEQ--ELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLARNG 556 ++ L + +++ E + + YT+ TGR + R+A I S E+L RKL N Sbjct: 2763 QEKAEQLLTAIKQKRYCETDLIRIAYTLQTGREAMEERLAFIAESLEDLERKLNDFIEN- 2821 Query: 557 AGTYKAEDIYYRKLERNLKFIG-------KSMTGSGGLTESSHKSIADLQLLCGAYCDGA 609 KA+ +Y +++ N K + +++ + + DL + G Sbjct: 2822 ----KADSLYLDRIDDNKKALAVLSADEDTEKIIEAWMSKGKYTKLLDL------WVKGL 2871 Query: 610 DMDFEGIYRQLDCRKVSWPTYAFEQKRLW 638 D+ +Y ++S P Y F ++R W Sbjct: 2872 SFDWGMLYGTQTPVRISLPAYPFAKERYW 2900 Score = 375 bits (962), Expect = e-102, Method: Compositional matrix adjust. Identities = 225/623 (36%), Positives = 332/623 (53%), Gaps = 50/623 (8%) Query: 32 AVKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGK 91 +++ + + IAIIGMSG+F +A+ + W+ L GK CI +IP R+ D R + Sbjct: 3523 SIRQVHDEPIAIIGMSGRFPQADSVHELWDNLKNGKSCISDIPGERR-DWGR-----ANR 3576 Query: 92 SPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKL 151 P E A+L +ID+FD FF I P EA+ +DPRQ +FLE AW T EDAGY G ++ Sbjct: 3577 DP-EKAVPRWGAFLKDIDRFDPLFFQISPKEAESMDPRQPIFLEEAWHTFEDAGYMGDRI 3635 Query: 152 CGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILDFKGPSM 211 G GVYVG+ EY L GD I G + ++ R+AY LD KGP+M Sbjct: 3636 KGKSCGVYVGVEEG-----EYAHLT--GDTDYIN----GTQNATLSARIAYALDLKGPNM 3684 Query: 212 MIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGITSSDSSIRT 271 + ACSS LVA+H AC A++ +CE AL GV + I E + S + + Sbjct: 3685 ALTAACSSGLVAIHQACSALRQGDCEMALAAGVTLNI-SHMSFEALTRAEMLSPNGQCKV 3743 Query: 272 FDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMTAQEN 331 FD A+G GE VAAVL+KPL KAI D+DHIY IK S VN DG + GITAPN +Q Sbjct: 3744 FDQDANGLVPGEAVAAVLLKPLSKAIEDKDHIYGCIKASGVNYDGKTNGITAPNPFSQAE 3803 Query: 332 VITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSVKTNI 391 +I + +++ I+P + Y AH TG+ LGDP+EV A+ F+++T +KQFC I S+K I Sbjct: 3804 LIENIYEKNEINPLDIQYVMAHSTGSNLGDPLEVQALTSVFSKYTKQKQFCMISSIKPLI 3863 Query: 392 GHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWKGYDGVY 451 GH + +G LI +MA++ + IP + H + N I F SP + + W + Sbjct: 3864 GHTFAASGTVALISMLMAMKNQIIPATHHCESENPYIPFKESPFVLCKENRSWIKKNQKP 3923 Query: 452 RCG-ISSFGLSGTNAHVVLE----GPPPLEQRQDEVPANHIFTVSAKTEASLEKLILNYL 506 R G IS+ G+SGTNAH V+E P QR P IF +SA+ + L+ + Sbjct: 3924 RMGTISTTGISGTNAHAVIEEYIPDDQPSTQRHQGSP--QIFVISAQNDDRLQDAACRMI 3981 Query: 507 EFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLA---RNGAGTYKAE 563 +L + L + D+ YT+ GR + R+A++ ++ E+L+RKLK +NG + + Sbjct: 3982 AYLEQNHNLSLPDVAYTLQVGRKAMEARLAIVANNQEQLVRKLKEYVEAMKNGGVSGQQR 4041 Query: 564 DIYYRKLERNLKFIGKSMTGSGGLTESSHKSIA-------DLQLLCGAYCDGADMDFEGI 616 +Y E G+ E +++ +L+ + + G + +E + Sbjct: 4042 SLYTGYTE--------------GILEEQDEAVLQALAKERNLENIAECWVKGYQIPWELL 4087 Query: 617 YRQLDCRKVSWPTYAFEQKRLWV 639 + D R VS P Y F ++R W+ Sbjct: 4088 HDGDDVRMVSLPGYPFARERYWI 4110 Score = 127 bits (319), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 141/569 (24%), Positives = 239/569 (42%), Gaps = 81/569 (14%) Query: 1006 KVIEAIPGQAFSERGEQAYSLGGRQE--DYDKLFAAI--ELQKISQIIHLMTIQDHSAEG 1061 KVI G+ +S++ E +Y + RQE ++K F +I EL + I+++ ++D Sbjct: 2972 KVIFISQGEVYSKQSEYSYQIV-RQEPVTFEKAFQSIKEELGEPDAILYMWPMEDKRCIK 3030 Query: 1062 GHQQLEYNLKLGLDSLFYLSQSIMKHPNDPVELVL---FAEHVHRISGSETAVNPHHAAF 1118 H + YL Q + P L+L F + + R + ++ Sbjct: 3031 DH-----------SCIVYLLQGMSAAKLHPSRLLLAGCFEDSLDR---------SYLESW 3070 Query: 1119 FGLGKVLGKEYSKLNVRCIDIDGETRAAE-CIREINGEKQV---ELVGYREGRPYVQELQ 1174 G + LG V I E + + R++ E Q + V Y+ + YV ++ Sbjct: 3071 IGFERSLGLVLPHTKVTGIFQPAEQGSMDDWTRKVWAELQASTEQTVLYQNLKRYVNHIE 3130 Query: 1175 AVPVPALPDQQAEIKKDGVYIITXXXXXXXXEVARYLSSLAKVNLILVGRSGLSHPIDPG 1234 + PD +++K G Y+IT A++L+ NLIL GRS Sbjct: 3131 QTTIQ--PDN-SKLKSGGTYLITGGVGGLGYLFAKHLAKNYAANLILTGRSPF------- 3180 Query: 1235 SKNHTRTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEG 1294 N + + + ++ G +ADV+D M + + + R+ +ING+ H AG+ + Sbjct: 3181 --NDEKQKQIKELKDLGGERMYAEADVSDPIAMGDCVKRGKDRFGAINGVIHAAGIESDS 3238 Query: 1295 FIFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAY 1354 IF K +F R+ PKI GT LD+ + LDF FSS +++ G G DY N + Sbjct: 3239 AIFDKKIESFQRIIEPKINGTIALDEWLKNEDLDFMCYFSSSSAVLGDFGCCDYAIGNRF 3298 Query: 1355 LDSYAEYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTEENQNEQGFKNIGTRE 1414 +YA+YR+ + KT INW WKD GM K+G E T+ G + + E Sbjct: 3299 QMAYAQYRNELH-NGKTFVINWPVWKDGGM------KIGDEETTDMYLKSSGQRFLEAEE 3351 Query: 1415 AIEALNVVLNKEISK--VIIGELDDKVFGLYKDQITFSLAPEIAAR-IRPTRPKAPGHTG 1471 I +L ++ ++ VI G+ P +R + T P P Sbjct: 3352 GIRMFEHILAQQDAQHLVIAGQ------------------PSRVSRFLGMTEPAIPEPAT 3393 Query: 1472 LPPVPMEHRDYS---GIESAI---VKAWVKVL---GLEQININDKFYDLGGDSISAIYLV 1522 P+ E++D IE + +K + L +++N+N + D G DSI Sbjct: 3394 QAPLAQENKDEVKTLSIEKRLEHDLKEHIHTLLKISKDRLNLNKNWADFGFDSIYLAKFS 3453 Query: 1523 KEIGKVFPSLIDISDIFTYPSISEMSDYI 1551 + K F + + F Y ++ E+ + Sbjct: 3454 NVLSKHFNIEVTPALFFGYSTLQELISFF 3482 >emb|CAB13602.2| polyketide synthase of type I [Bacillus subtilis subsp. subtilis str. 168] Length = 4538 Score = 529 bits (1362), Expect = e-148, Method: Compositional matrix adjust. Identities = 473/1613 (29%), Positives = 734/1613 (45%), Gaps = 279/1613 (17%) Query: 40 DIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDTQY 99 DIAIIG++G++ +A ++ FW L +GK+C+ EIP R D R G SP Sbjct: 435 DIAIIGLAGRYPKAANIHEFWNNLKEGKDCVSEIPESR-WDWQR---LEGITSPSGKDIS 490 Query: 100 TRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLC---GSKT 156 ++D+ D FD FF I P EA+ +DP++RLFLE+ W T+EDAGY L G Sbjct: 491 KWGGFIDDPDCFDPQFFRITPREAETMDPQERLFLETCWETIEDAGYTPKTLAKPKGRNK 550 Query: 157 GVYVGLSSDGXXXXEYFKLIEQGDPSLIGL--STAGNIKSV------IAGRLAYILDFKG 208 +VG+ F + D +L+G ++A N+ + IA R++Y +F G Sbjct: 551 RQHVGV----------FAGVMHKDYTLVGAEEASAENVFPLSLNYAQIANRVSYFCNFHG 600 Query: 209 PSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGI---TSS 265 PSM +DT CSSSL A+H+A ++I++ EC+ AL GGVN+ + P + G+ S+ Sbjct: 601 PSMAVDTVCSSSLTAVHLALESIRHGECDVALAGGVNLSLHPN----KYMTYGVWDMFST 656 Query: 266 DSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPN 325 D RTF DG EG+ AVL+KPL +A D D IYAVIKGSAVN G+ GI+ P+ Sbjct: 657 DGHCRTFGKDGDGYVPAEGIGAVLLKPLRQAEEDGDRIYAVIKGSAVNHVGTVSGISVPS 716 Query: 326 MTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIG 385 +Q ++I ++ IDP+T++Y EAHGTGT LGDPIE+ + +AF ++T +QFC+IG Sbjct: 717 PVSQADLIETCLEKTGIDPRTISYVEAHGTGTSLGDPIEIQGLVKAFRQYTQDRQFCSIG 776 Query: 386 SVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK 445 SVK+NIGH +S AG++GL K + + ++K+ PSLH + N + F SP YV +T WK Sbjct: 777 SVKSNIGHAESAAGISGLSKVALQLHHQKLVPSLHSEELNPYVDFEKSPFYVQHETETWK 836 Query: 446 -------GYDGVY--RCGISSFGLSGTNAHVVLEGPPPLEQRQD-----EVPANHIFTVS 491 G D Y R GISSFG +G+NAH++LE P QD + + + +S Sbjct: 837 QPVIKENGEDVPYPRRAGISSFGATGSNAHIILEEHIPQAAEQDVSLSSDSDISAVIPLS 896 Query: 492 AKTEASLEKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKL 551 A+ + L L+FL ++I DL YT+ GR P + R++ + S +EL +LK Sbjct: 897 ARNQERLRVYAKRLLDFL--HDGIQIRDLAYTLQVGREPMEERVSFLASGIQELSDQLKA 954 Query: 552 LARNGAGTYKAEDIYYRKLERNLKFIGKSMTGS--GGLTESSHKSIADLQL--LCGAYCD 607 I RK ++ + G+ GS ES HK + +L + + + Sbjct: 955 F------------IEGRKAIQHC-WKGRVSRGSEPSRPAESVHKLLEQRKLDQIAEQWAN 1001 Query: 608 GADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVELPESR--RSLTAARTRHPLLQERAVSS 665 G+ +D++ +Y +++S PTY FE+ R WV E + RS HPLL + VS Sbjct: 1002 GSGVDWKLLYEGSKPKRISLPTYPFERVRYWVPKAEKKTDRSKQERHILHPLLHQN-VSD 1060 Query: 666 LNLEVYVSYLNVQDFWVLNEHQVNDACVIPGTAYLDMAKEIGTRHFGEARDIILSDVSFL 725 ++ + S ++F+ L +H + V+PG A L+M + R A D + Sbjct: 1061 ISGVRFRSAFTGREFF-LKDHVIKGEHVLPGAALLEMVRAAVER---AAADQFPTGFRLR 1116 Query: 726 NLLKVEKDEVKEIHTIVNIK-----DDALKFTVASRASAAEEW-IKHAEAWIGRKERQPH 779 N++ V V E ++++ + + F + +AEE I + + E + Sbjct: 1117 NIVWVRPFAVTEQQKDIDVRLYPEENGEITFEICRDPESAEESPIVYGQGSAVLCEAGEN 1176 Query: 780 TTYDIETLKTTYDSVYAIRRNQSWPVIEESSYTSVQYVEDTNRPESIINVGGRWKCTNAI 839 +IE LK +Y+ R S P +YT E I+ G + +++ Sbjct: 1177 PVINIEELKASYNG-----RTLS-PFDCYEAYT-----------EMGIHYGDSHRAIDSL 1219 Query: 840 YRSKEGVLCELEIQAEYAEDLEQFYLHPAMMDCAVNA------GTFTINED--TYLPYYY 891 Y + GVL +L + ++ + + LHP+M+D A A G T ED LP+ Sbjct: 1220 YAGENGVLVKLTMPPVISDTEDHYILHPSMIDSAFQASIGLRLGGATSLEDRKAMLPFAI 1279 Query: 892 KEFRIFGPTPKKFYSYIT--KKNNENEETGKFDLLLLNEQGEVFGEISSYIVKRVHSFTP 949 ++ RIF ++ IT + + + K D+ L NE+G+V ++SY + + T Sbjct: 1280 QDVRIFKGCEASMWARITYSEGSTAGDRMQKLDIDLCNEEGQVCVRLTSYSARVLE--TD 1337 Query: 950 LEQPSAQKSIYHKLGWVEKNEYKLLRRSEANGGILLFHNQAKLAGEIIASLRQAGKKVIE 1009 E P SEAN +L H + A E + KV+ Sbjct: 1338 QEGP-----------------------SEANDTLLFEHIWEERAAERQELIEYDTYKVV- 1373 Query: 1010 AIPGQAFSERGEQAYSLGGR---------QEDYDKLFAAIELQKISQIIHLMTIQDHSAE 1060 + GEQ SL E D+ F +Q +I LM HS Sbjct: 1374 ------VCDVGEQMESLQNHLDCTVLQHDTETIDERFEGYAIQLFEEIKQLM----HSKT 1423 Query: 1061 GGHQQLEYNLKLGLDSLFYLSQSIMKHPNDPVELVLFAEHVHRISGSETAVNPHHAAFFG 1120 GGH ++ + LD LS G Sbjct: 1424 GGHTFIQVAVP-ALDEPQLLS-----------------------------------GLTG 1447 Query: 1121 LGKVLGKEYSKLNVRCIDIDGETRAAECIREINGEKQVEL---VGYREGRPYVQELQAVP 1177 L K E KL + I+I+ A E + ++ + + +G+ +V + + V Sbjct: 1448 LLKTAELENPKLTGQLIEIETGMSAGELFEILEENRRYPRDTHIRHWQGKRFVSKWKEVS 1507 Query: 1178 VPALPDQQAEIKKDGVYIITXXXXXXXXEVARYLSSLAK-VNLILVGRSGLSHPIDPGSK 1236 L K GVY+IT A +++ +IL GRS P+D K Sbjct: 1508 GEHL-SADMPWKDKGVYLITGGAGGLGFIFATEIANQTNDAVVILTGRS----PLDERKK 1562 Query: 1237 NHTRTEIMNHIRANGSNVDCY-QADVADEREMQAMLAQLRQRYTSINGIFHCAGVAGEGF 1295 + I+A Y QAD+AD++ + A+L + + Y ++GI H AG+ + F Sbjct: 1563 KKLKALQKLGIQA------IYRQADLADKQTVDALLKETQNVYGDLDGIIHSAGLIKDNF 1616 Query: 1296 IFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANAYL 1355 I +K K V PK+ G LD+ T + LDFF++FSS GS GQADY ANA++ Sbjct: 1617 IMKKKKEEVQTVLAPKVAGLIHLDEATKDIPLDFFILFSSGAGAVGSAGQADYAMANAFM 1676 Query: 1356 DSYAEYRS----LIKPEQKTLTINWCGWKDTGMLADYRNK--LGKEAGTEENQNEQGFKN 1409 ++++EYR+ L K KTL++ W WKD GM D L +E G + ++G + Sbjct: 1677 NAFSEYRNGQAELHKRYGKTLSVCWPLWKDGGMQIDAETARMLKRETGMVAMETDRGIQA 1736 Query: 1410 I---------------GTREAIEAL---------------NVVLNKEISKV-IIGELDDK 1438 + G + I A LN+E K +IGE+D++ Sbjct: 1737 LYHGWTSGKPQVLVASGVTDRIRAFLHETGHGKGQSHNIKKSSLNQEAEKADMIGEIDEE 1796 Query: 1439 VFGLYKDQITFSLAPEIAARIRPTRPKAPGHTGLPPVPMEHRDYSGIESAIVKAWVKVLG 1498 + R KA + + + S+++K L Sbjct: 1797 IL----------------------REKAENY------------FKQVLSSVIK-----LP 1817 Query: 1499 LEQININDKFYDLGGDSISAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYI 1551 QI+ D G DSI +++ ++ KVF SL + F Y I ++ Y Sbjct: 1818 AGQIDAEAPLEDYGIDSIMIMHVTGQLEKVFGSL-SKTLFFEYQDIRSLTRYF 1869 Score = 400 bits (1028), Expect = e-109, Method: Compositional matrix adjust. Identities = 245/636 (38%), Positives = 351/636 (55%), Gaps = 46/636 (7%) Query: 33 VKPMSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKS 92 V+ +IAIIG+SG++ +A+++ WE L G++CI EIP R D L + K Sbjct: 1921 VREKETEEIAIIGISGRYPQADNIDELWEKLRDGRDCITEIPADR---WDHSLYYDEDKD 1977 Query: 93 PHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLC 152 T ++ ++DKFD FF I P EAKL+DP++RLFL+ + T+EDAGY L Sbjct: 1978 KPGKTYSKWGGFMKDVDKFDPQFFHISPREAKLMDPQERLFLQCVYETMEDAGYTREHL- 2036 Query: 153 GSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLI---GLSTAGNIKSVIAGRLAYILDFKGP 209 G K +G S Y + G + L+ GN S IA R++Y DF GP Sbjct: 2037 GRKRDAELGGSVGVYVGVMYEEYQLYGAQEQVRGRSLALTGN-PSSIANRVSYYFDFHGP 2095 Query: 210 SMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIG---ITSSD 266 S+ +DT CSSSL A+H+ACQ+++ ECEAA GGVN+ I P L +G SS Sbjct: 2096 SIALDTMCSSSLTAIHLACQSLQRGECEAAFAGGVNVSIHPN----KYLMLGQNKFMSSK 2151 Query: 267 SSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNM 326 +F DG GEGV AVL+KPL KA+ D DHIY +IKG+A+N G + G + PN Sbjct: 2152 GRCESFGQGGDGYVPGEGVGAVLLKPLSKAVEDGDHIYGIIKGTAINHGGKTNGYSVPNP 2211 Query: 327 TAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGS 386 AQ +VI A+ EA++DP+TV+Y EAHGTGT LGDPIE+ + + F + TD KQFCAIGS Sbjct: 2212 NAQADVIKKAFVEAKVDPRTVSYIEAHGTGTSLGDPIEITGLSKVFTQETDDKQFCAIGS 2271 Query: 387 VKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWK- 445 K+NIGH +S AG+AG+ K ++ ++YR + PSLH V N NI F +SP V + +WK Sbjct: 2272 AKSNIGHCESAAGIAGVTKVLLQMKYRHVAPSLHSNVLNPNIDFLNSPFKVQQELEEWKR 2331 Query: 446 ------GYD-GVYR-CGISSFGLSGTNAHVVLE--GPPPLEQRQDEVPANHIFTVSAKTE 495 G D + R G+SSFG G NAH+++E P P+E+R + +SAK E Sbjct: 2332 PIISVNGKDIELPRIAGVSSFGAGGVNAHILIEEYAPEPVEERLPARKQPAVIVLSAKNE 2391 Query: 496 ASLEKLILNYLEFLGKEQELRISDL---CYTVNTGRLPNQCRIAMIVSSTEELIRKLKLL 552 L+K L + +EQ +DL YT+ GR + R+A + + +EL KL Sbjct: 2392 ERLQKRPERLLHAI-REQTYVEADLHRIAYTLQVGREAMKERLAFVAETMQELEEKLYEC 2450 Query: 553 ARNGAGTYKAEDIYYRKLERNLKFIGK-------SMTGSGGLTESSHKSIADLQLLCGAY 605 +GT E +Y +++ N + I S T L + + + DL + Sbjct: 2451 I---SGTENREYVYRGQVKSNKEAIAAFAADEDMSKTIEAWLQKGKYAKVLDL------W 2501 Query: 606 CDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVEL 641 G +D+ +Y+ R++S P Y F + R W+++ Sbjct: 2502 VRGLRIDWSTLYQDQKPRRISLPAYPFARDRYWIDV 2537 Score = 382 bits (982), Expect = e-104, Method: Compositional matrix adjust. Identities = 233/640 (36%), Positives = 360/640 (56%), Gaps = 44/640 (6%) Query: 38 ESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDT 97 E IAI+GMSG++ A ++R +W+ L+ + IR+IP R D D+Y + K + Sbjct: 2873 EDAIAIVGMSGRYPGARNVREYWDNLVHARNAIRDIPTSR-WDVDKYYDPVLNK---KGK 2928 Query: 98 QYTR-IAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLCGSKT 156 Y + + LD+I+ FD FF I P+EA+L+DP+ R+FL+ + EDAGY L K Sbjct: 2929 VYCKSMGMLDDIEHFDPLFFNIPPSEAELMDPQHRIFLQEGYKAFEDAGYNARTLNEKKC 2988 Query: 157 GVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGRLAYILDFKGPSMMIDTA 216 GVY+G+ S+ EY ++ + + + GN ++ A R+ Y L+ KGP++ IDTA Sbjct: 2989 GVYLGIMSN-----EYGVMLNRQSRA----NATGNSFAIAAARIPYFLNLKGPAIPIDTA 3039 Query: 217 CSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLNIGITSSDSSIRTFDDQA 276 CSSSLV H+A QA+ N E + ALVGGV++ + P++ + G+ S D + FD+ A Sbjct: 3040 CSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYM-SMCEAGMLSPDGQCKAFDNGA 3098 Query: 277 DGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMTAQENVITDA 336 +G GEG A+++K L A DRDHIY +I GS +NQDG + GITAP+ +Q ++ D Sbjct: 3099 NGFVPGEGAGALVLKRLKDAEADRDHIYGIIIGSGINQDGKTNGITAPSAKSQMDLERDI 3158 Query: 337 WKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSVKTNIGHLDS 396 ++ I P++++Y E HGTGTK GDPIE+ A+ F TD+KQFCAIGSVK+NIGH + Sbjct: 3159 YETYGIHPESISYVEMHGTGTKQGDPIELEALSTVFQEKTDKKQFCAIGSVKSNIGHTSA 3218 Query: 397 LAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVNDQTTDWKGYDG-VYRCGI 455 AG+AG+ K ++ + ++ + P+L+F PN + +F SP+YVN + W+ DG R + Sbjct: 3219 AAGVAGVQKVLLCMNHKTLVPTLNFTTPNEHFEFEHSPLYVNTELKPWETADGKPRRACV 3278 Query: 456 SSFGLSGTNAHVVLEGPPPLEQRQDEVPANH---IFTVSAKTEASLEKLILNYLEFLGKE 512 SSFG SGTNAH+V+E P E+R D + H +F +SAK E L+ +F+ Sbjct: 3279 SSFGYSGTNAHIVIEEYQP-EKRNDRLTKQHRSALFVLSAKKEKQLKAYAEAMKDFVTSN 3337 Query: 513 QELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKL-KLLARNGAGTYKAEDIYYRKLE 571 +++ + D+ YT+ TGR R+A + S E LI+ L LA + A + +K E Sbjct: 3338 EDIDLEDMAYTLQTGREAMDYRMAFLADSREMLIKALDDYLAEMPNASIFAAHVKTKKSE 3397 Query: 572 RNLKFIGKSMTGSGGLTESSHKSIADLQL---------LCGAYCDGADMDFEGIYRQLDC 622 L E+ H + A LQ + + G +D+ +Y + Sbjct: 3398 IK-------------LFETDHDAKALLQTWIEKKRLEKVAELWVKGLQIDWNKLYGEYTP 3444 Query: 623 RKVSWPTYAFEQKRLWVELPESR-RSLTAARTRHPLLQER 661 R++S P Y F ++ W+ E ++ A + L+ +R Sbjct: 3445 RRISLPAYPFAEEYYWLPTQEGEPETIATAMPQFELMPKR 3484 Score = 228 bits (580), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 141/446 (31%), Positives = 239/446 (53%), Gaps = 58/446 (13%) Query: 40 DIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKADADRYLEFSGGKSPHEDTQY 99 DIAIIG+S +F A L +W+++ G+ I +P R ++ ++G Sbjct: 4084 DIAIIGLSCRFPGAETLEEYWDLIRDGRSAIAPVPPERFGNSSS--NYAG---------- 4131 Query: 100 TRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWSTLEDAGYGGGKLCGSKTGVY 159 +DE+++FD FF + ++ + +DP+ LE + AGY ++ G + GVY Sbjct: 4132 ----LIDEMNRFDHDFFMMSESDVRAMDPQALAVLEESLKLWYHAGYTEKEVKGMRAGVY 4187 Query: 160 VGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNI-----KSVIAGRLAYILDFKGPSMMID 214 +G S Q P LS A N ++ +A ++ D KGPS+++D Sbjct: 4188 IGGRS-------------QHKPDPASLSKAKNPIVAGGQNYLAANISQFFDLKGPSILLD 4234 Query: 215 TACSSSLVALHVACQAIKNHECEAALVGGVNI------KIFPKTEEENNLNIGITSSDSS 268 TACSS+LV L++A QA+++ + EAA+VGGV++ ++F + G+ S Sbjct: 4235 TACSSALVGLNMAIQALRSGDIEAAVVGGVSLLDADAHRMFHER--------GLLCDKPS 4286 Query: 269 IRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSVGITAPNMTA 328 FD +ADG GEGV VL+K +++A+ D D IYAVIK +A+N DG + G ++PN+ A Sbjct: 4287 FHIFDKRADGVILGEGVGMVLVKTVNQAVEDGDSIYAVIKAAAINNDGRTAGPSSPNLEA 4346 Query: 329 QENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRKQFCAIGSVK 388 Q++V+ A +++ + ++Y EA+G+G+ + D +E+ AI + ++ K +GSVK Sbjct: 4347 QKDVMLSALEKSGKKTEEISYLEANGSGSAVTDLLELKAIQSIYR--SESKAPLGLGSVK 4404 Query: 389 TNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQF---SSSPVYVNDQTTDWK 445 NIGH G+A LIK + +++R++ P F N N+ + + +Y + +WK Sbjct: 4405 PNIGHPLCAEGIASLIKVALMLKHRQLVP---FLSGNENMPYFDIEKTDLYFSRSQAEWK 4461 Query: 446 GYDGVYRCGISSFGLSGTNAHVVLEG 471 + I+ F GTNAH+++EG Sbjct: 4462 --ETTPAAAINCFADGGTNAHLIIEG 4485 Score = 116 bits (290), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 120/461 (26%), Positives = 200/461 (43%), Gaps = 54/461 (11%) Query: 1116 AAFFGLGKVLGKEYSKLNVRCIDIDGETRAAECIREINGE---KQVEL-VGYREGRPYVQ 1171 A+ GL ++L EYS L R D++ E E R I E K E V YR G+ Y Sbjct: 3606 ASRAGLYRMLQSEYSHLTSRHADMECEASHEELARLIAVEYYAKSTESEVCYRNGQRYRA 3665 Query: 1172 ELQAVPV-PALPDQQAEIKKDGVYIITXXXXXXXXEVARYLSSLAKVN-LILVGRSGLSH 1229 L P AL +Q D V +IT AR+ V L+L+GR L Sbjct: 3666 YLTEQPAEAALSHKQVSFSTDKVLLITGGTRGLGLLCARHFVKTYGVKRLVLIGREELP- 3724 Query: 1230 PIDPG-----SKNHTRTEIMNHIRANGSNVDCYQADVADEREMQAMLAQLRQRYTSINGI 1284 P D S + + + + G+ V D+ D ++ L + + +I G+ Sbjct: 3725 PRDQWNSVKISSLAEKIKAVQELEDMGAQVQVLSLDLTDRVAVEQSLKTIHETMGAIGGV 3784 Query: 1285 FHCAGVAGE---GFIFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSG 1341 HCAG+ + FI RK +V PK++G + L L ++ L FF +FSS+++ Sbjct: 3785 IHCAGMVNKQNPAFI-RKSLEEIGQVLEPKVEGLQTLFDLLQDEPLAFFTLFSSVSAAIP 3843 Query: 1342 SM--GQADYTAANAYLDSYAEYRSLIKPEQKTLTINWCGWKDTGMLADYRNKLGKEAGTE 1399 ++ GQADY ANA++D +AE P ++I W WK+TG L + R+K ++ G Sbjct: 3844 ALAAGQADYAMANAFMDYFAEAHQDKCP---IVSIQWPNWKETG-LGEVRSKALEQTGLI 3899 Query: 1400 ENQNEQGFKNIGTREAIEALNVVLNKEISKVIIGELDDKVFGLYKDQITFSLAPEIAARI 1459 N++G ++ L+ +L+ V++ + D ++K + + A Sbjct: 3900 SLTNDEG---------LQLLDQILSDRQYAVVLPAVPDT--NVWKPDKLMQPSLPVEALS 3948 Query: 1460 RPTRPKAPGHTGLPPVPMEHRDYSGIESAIVKAWVKVLGLEQINI-------NDKFYDLG 1512 P + L P ++ W+ L +++ I ++ F + G Sbjct: 3949 HPETKEQTSTRNLFPETVD--------------WLVTLFSDELKIAAEDFETDEPFQEYG 3994 Query: 1513 GDSISAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYIQS 1553 DSI LV+++ + ID S +F YP+I + ++ S Sbjct: 3995 IDSIILAQLVQQMNQQLNGDIDPSILFEYPTIESFAHWLIS 4035 >pir||T44806 mycosubtilin synthetase chain mycA [imported] - Bacillus subtilis gb|AAF08795.1| MycA [Bacillus subtilis] Length = 3971 Score = 513 bits (1321), Expect = e-143, Method: Compositional matrix adjust. Identities = 284/635 (44%), Positives = 377/635 (59%), Gaps = 23/635 (3%) Query: 16 FTASTLESEDRLLRDSAVKPM--SESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREI 73 A +E+ + + KP S DIAIIGMS A++ FW +L G+ IRE Sbjct: 645 LAAFLVENHSEIKQTDTAKPSRSSSKDIAIIGMSLNVPGASNKSDFWHLLENGEHGIREY 704 Query: 74 PLHRKADADRYLEFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLF 133 P R DA YL KS + Q+ R YLDEID+FD FFG+ P AK +DP QRLF Sbjct: 705 PAPRVKDAIDYLR--SIKSERNEKQFVRGGYLDEIDRFDYSFFGLAPKTAKFMDPNQRLF 762 Query: 134 LESAWSTLEDAGYGGGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIK 193 L+SAW +EDAGY G + GS+ GVYVG S G +Y +L+ P + GN+ Sbjct: 763 LQSAWHAIEDAGYAGDTISGSQLGVYVGYSKVGY---DYERLLSANYPEELHHYIVGNLP 819 Query: 194 SVIAGRLAYILDFKGPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTE 253 SV+A R+AY L+ KGP++ +DTACSSSLVA+H+AC+A+ +CE AL GG+ + P Sbjct: 820 SVLASRIAYFLNLKGPAVTVDTACSSSLVAVHMACKALLTGDCEMALAGGIRTSLLPM-- 877 Query: 254 EENNLNIGITSSDSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVN 313 + + + SSD +TF +DGT SGEGVAAVL+KPL AIRD DHIY VIKGSA+N Sbjct: 878 ---RIGLDMESSDGLTKTFSKDSDGTGSGEGVAAVLLKPLQAAIRDGDHIYGVIKGSAIN 934 Query: 314 QDGSSVGITAPNMTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFN 373 QDG++VGITAP+ AQ VI AWK+A I P+T+++ EAHGTGTKLGDP+E + + +AF Sbjct: 935 QDGTTVGITAPSPAAQTEVIEMAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGLCKAFE 994 Query: 374 RFTDRKQFCAIGSVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSS 433 + T++KQFCAIGSVK NIGHL AG+ GLIK+ + + ++KIPP HF PN I F SS Sbjct: 995 KVTEKKQFCAIGSVKANIGHLFEAAGIVGLIKSALMLNHKKIPPLAHFNKPNPLIPFHSS 1054 Query: 434 PVYVNDQTTDWKGYDGVYRCGISSFGLSGTNAHVVLEG-PPPLEQRQDEVPANHIFTVSA 492 P YVN + D+ D R GISSFG SGTNAHVVLE P E ++ H+F +SA Sbjct: 1055 PFYVNQEVMDFTPEDRPLRGGISSFGFSGTNAHVVLEEYTPESEYAPEDGNDPHLFVLSA 1114 Query: 493 KTEASLEKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLL 552 TEASL +L Y +++ + + + +CYT +TGR +AMIVSS +ELI KL L Sbjct: 1115 HTEASLYELTHQYRQYISDDSQSSLRSICYTASTGRAHLDYCLAMIVSSNQELIDKLTSL 1174 Query: 553 ARNGAGTYKAEDIYYRKLER-------NLKFIGKSMTGSGGLTESSHKSIADLQLLCGAY 605 + G Y+ ++ NL + T+ + I L + Y Sbjct: 1175 IQ-GERNLPQVHFGYKNIKEMQPAEKDNLSKQISDLMQHRPCTKD--ERITWLNRIAELY 1231 Query: 606 CDGADMDFEGIYRQLDCRKVSWPTYAFEQKRLWVE 640 A +D+ +Y +K P Y FE+ R WVE Sbjct: 1232 VQRAVIDWRAVYSNEVVQKTPLPLYPFERNRCWVE 1266 >dbj|BAB69698.1| iturin A synthetase A [Bacillus subtilis] Length = 3982 Score = 508 bits (1308), Expect = e-142, Method: Compositional matrix adjust. Identities = 275/635 (43%), Positives = 379/635 (59%), Gaps = 25/635 (3%) Query: 22 ESEDRLLRDSAVKP--MSESDIAIIGMSGKFGEANDLRAFWEVLLKGKECIREIPLHRKA 79 ES + +D+A KP ++ DIAIIGMS A+ FW +L KG+ IRE P R Sbjct: 650 ESRAEIKQDAAAKPSHVTPKDIAIIGMSLNVPGASTKSDFWNLLEKGEHSIREYPESRLK 709 Query: 80 DADRYLEFSGGKSPHEDTQYTRIAYLDEIDKFDCGFFGILPNEAKLIDPRQRLFLESAWS 139 DA YL+ +S ++Q+ + YLDEID+FD FFG+ P A+ +DP QRLFL+SAW Sbjct: 710 DAADYLK--SIQSEFNESQFVKGGYLDEIDRFDYSFFGLAPKTAQFMDPNQRLFLQSAWH 767 Query: 140 TLEDAGYGGGKLCGSKTGVYVGLSSDGXXXXEYFKLIEQGDPSLIGLSTAGNIKSVIAGR 199 +EDAGY GG + GS+ GVY G S G +Y +L+ P + GN+ SV+A R Sbjct: 768 AIEDAGYAGGSMNGSRVGVYAGYSKVGY---DYERLLSANYPEELHQYIVGNLPSVLASR 824 Query: 200 LAYILDFKGPSMMIDTACSSSLVALHVACQAIKNHECEAALVGGVNIKIFPKTEEENNLN 259 +AY L+ KGP++ +DTACSSSL A+H+AC+++ + +CE AL GG+ + P + Sbjct: 825 IAYFLNLKGPAVTVDTACSSSLAAVHMACKSLMSGDCEMALAGGIRTSLLPIC-----IG 879 Query: 260 IGITSSDSSIRTFDDQADGTNSGEGVAAVLIKPLDKAIRDRDHIYAVIKGSAVNQDGSSV 319 + + SSD +TF +DGT +GEG AAVL+KPL A+RD DHIY VIKGSA+NQDG++ Sbjct: 880 LDMESSDGYTKTFSKDSDGTGTGEGAAAVLLKPLQDAVRDGDHIYGVIKGSAMNQDGTTA 939 Query: 320 GITAPNMTAQENVITDAWKEARIDPQTVTYWEAHGTGTKLGDPIEVHAIHRAFNRFTDRK 379 GITAPN AQ VI AWK+A I P+T+++ EAHGTGTKLGDP+E + + +AF ++T +K Sbjct: 940 GITAPNPAAQTEVIETAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGLCKAFEKYTAKK 999 Query: 380 QFCAIGSVKTNIGHLDSLAGLAGLIKAVMAIQYRKIPPSLHFKVPNRNIQFSSSPVYVND 439 QFCAIGSVK+NIGHL AG+ GLIK+V+ + ++K PP HF PN I F SSP YVN Sbjct: 1000 QFCAIGSVKSNIGHLFEAAGIVGLIKSVLMLNHKKNPPLAHFNEPNPLIHFHSSPFYVNQ 1059 Query: 440 QTTDWKGYDGVYRCGISSFGLSGTNAHVVLEG-PPPLEQRQDEVPANHIFTVSAKTEASL 498 + ++ D R G+SSFG SGTNAHVVLE E ++ H+F +SA TE SL Sbjct: 1060 EAAEFTSGDEPLRGGVSSFGFSGTNAHVVLEEYISQSEYAPEDEHGPHLFVLSAHTEKSL 1119 Query: 499 EKLILNYLEFLGKEQELRISDLCYTVNTGRLPNQCRIAMIVSSTEELIRKLKLLA---RN 555 +L Y +++ + + + +CYT +TGR IAMIVS +EL KL L RN Sbjct: 1120 YELAQQYRQYVSDDSQASLKSICYTASTGRAHLDHGIAMIVSGKQELSDKLTRLIQGDRN 1179 Query: 556 GAGTYKAEDIYYRKLERNLKFIGKSMTGSGGL-----TESSHKSIADLQLLCGAYCDGAD 610 G Y I Y+ ++ L + + + + I L + GA Sbjct: 1180 LPGVY----IGYKNMKEMLPAHKEELNQQAAALIKQRLRTQDERITWLHRAAELFVQGAV 1235 Query: 611 MDFEGIYRQLDCRKVSWPTYAFEQKRLWVELPESR 645 +D+ +Y +K P Y FE+ R W E + R Sbjct: 1236 IDWRALYSGETVQKTPLPLYPFERSRCWAEADQLR 1270 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.134 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 2,376,862,522 Number of extensions: 102312597 Number of successful extensions: 262640 Number of sequences better than 1.0e-05: 1826 Number of HSP's gapped: 256131 Number of HSP's successfully gapped: 2902 Length of query: 1606 Length of database: 757,237,578 Length adjustment: 139 Effective length of query: 1467 Effective length of database: 379,838,817 Effective search space: 557223544539 Effective search space used: 557223544539 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)