BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0381.0001.p (314 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_388623.1| similar to ABC transporter (ATP-binding protein... 542 e-153 ref|NP_781267.1| ABC transporter ATP-binding protein [Clostridiu... 540 e-152 ref|NP_349931.1| ATPase component of ABC transporter (two ATPase... 517 e-145 ref|NP_561053.1| probable ABC transporter [Clostridium perfringe... 513 e-144 ref|NP_345268.1| ABC transporter, ATP-binding protein [Streptoco... 456 e-127 >ref|NP_388623.1| similar to ABC transporter (ATP-binding protein) [Bacillus subtilis] pir||D69813 ABC transporter (ATP-binding protein) homolog yfmM - Bacillus subtilis dbj|BAA22327.1| YfmM [Bacillus subtilis] emb|CAB12571.1| yfmM [Bacillus subtilis subsp. subtilis str. 168] Length = 518 Score = 542 bits (1396), Expect = e-153, Method: Compositional matrix adjust. Identities = 253/314 (80%), Positives = 286/314 (91%) Query: 1 LQEYENAFILISHDIPFLNSVINLIYHMENQSLTRYVGDYEYFQQVYEAKKSQLESAFKR 60 LQEYENAFILISHDIPFLNSVINLIYH+ENQ LTRYVGDY F +VYE KK QLE+A+K+ Sbjct: 205 LQEYENAFILISHDIPFLNSVINLIYHVENQELTRYVGDYHQFMEVYEVKKQQLEAAYKK 264 Query: 61 QQQEIADLKDFVARNKASVATRNMAMSRQKKLDKMEVIELAREKPKPQFNFKAGRTSGKL 120 QQQE+A+LKDFVARNKA V+TRNMAMSRQKKLDKM++IELA EKPKP+F+FK RTSGKL Sbjct: 265 QQQEVAELKDFVARNKARVSTRNMAMSRQKKLDKMDMIELAAEKPKPEFHFKPARTSGKL 324 Query: 121 IFETKDLVIGYDSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARLG 180 IFETKDLVIGYDSPLSRPLNL+MERGQKIAL GANGIGKTTLL+S+LG+I + GS G Sbjct: 325 IFETKDLVIGYDSPLSRPLNLRMERGQKIALYGANGIGKTTLLKSLLGEIQPLEGSVERG 384 Query: 181 DLLETGYFEQEIKGTNYNTCIEEIWAEFPSFTQFEIRAALAKCGLTTQHIESKIAVLSGG 240 + + TGYFEQE+K TN NTCIEE+W+EFPS+TQ+EIRAA AKCGLTT+HIES+++VLSGG Sbjct: 385 EHIYTGYFEQEVKETNNNTCIEEVWSEFPSYTQYEIRAAPAKCGLTTKHIESRVSVLSGG 444 Query: 241 EKAKVRLCKLINRETNLLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIV 300 EKAKVRLCKLIN ETNLLVLDEPTNHLD DAK+EL+RAL+ YKGSILLISHEP+FY DI Sbjct: 445 EKAKVRLCKLINSETNLLVLDEPTNHLDADAKEELKRALKEYKGSILLISHEPDFYMDIA 504 Query: 301 TDTWNCESWTTKVF 314 T+TWNCESWTTKV Sbjct: 505 TETWNCESWTTKVL 518 Score = 79.3 bits (194), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 61/232 (26%), Positives = 104/232 (44%), Gaps = 44/232 (18%) Query: 121 IFETKDLVIGY-DSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARL 179 I KDL G+ D + ++ ++ +G+ + L+GANG GK+T + I G++ G Sbjct: 3 ILSVKDLSHGFGDRAIFNNVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLEPDEGKVEW 62 Query: 180 GDLLETGYFEQEI---KGTN----------------------YNT-----------CIEE 203 + GY +Q KG + YN +EE Sbjct: 63 SKNVRVGYLDQHTVLEKGKSIRDVLKDAFHYLFAMEEEMNEIYNKMGEADPDELEKLLEE 122 Query: 204 IWAEFPSFTQFEIRAALAKC-------GLTTQHIESKIAVLSGGEKAKVRLCKLINRETN 256 + + T + +K GL+ +E + LSGG++ KV L KL+ + Sbjct: 123 VGVIQDALTNNDFYVIDSKVEEIARGLGLSDIGLERDVTDLSGGQRTKVLLAKLLLEKPE 182 Query: 257 LLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIVTDTWNCES 308 +L+LDEPTN+LD + L+R LQ Y+ + +LISH+ F ++ ++ E+ Sbjct: 183 ILLLDEPTNYLDEQHIEWLKRYLQEYENAFILISHDIPFLNSVINLIYHVEN 234 >ref|NP_781267.1| ABC transporter ATP-binding protein [Clostridium tetani E88] gb|AAO35204.1| ABC transporter ATP-binding protein [Clostridium tetani E88] Length = 518 Score = 540 bits (1390), Expect = e-152, Method: Compositional matrix adjust. Identities = 248/313 (79%), Positives = 287/313 (91%) Query: 1 LQEYENAFILISHDIPFLNSVINLIYHMENQSLTRYVGDYEYFQQVYEAKKSQLESAFKR 60 LQ+YENAFILISHDIPFLNSVINLIYHMEN L RYVG+Y+ F +VYEAKK QLE+A+K+ Sbjct: 205 LQDYENAFILISHDIPFLNSVINLIYHMENGELNRYVGNYDDFLKVYEAKKQQLEAAYKK 264 Query: 61 QQQEIADLKDFVARNKASVATRNMAMSRQKKLDKMEVIELAREKPKPQFNFKAGRTSGKL 120 QQQEI +LKDFV+RNKA V+TRNMAMSRQKKLDKM++IEL ++KPKP+FNFK GRTSGK+ Sbjct: 265 QQQEIQELKDFVSRNKARVSTRNMAMSRQKKLDKMDLIELPKDKPKPEFNFKEGRTSGKM 324 Query: 121 IFETKDLVIGYDSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARLG 180 +FETKDLVIGY+ LS+PLNL MERG+KIALVGANG+GKTTLL+SILG+I ISG A LG Sbjct: 325 LFETKDLVIGYNEALSKPLNLHMERGEKIALVGANGLGKTTLLKSILGEIKPISGHATLG 384 Query: 181 DLLETGYFEQEIKGTNYNTCIEEIWAEFPSFTQFEIRAALAKCGLTTQHIESKIAVLSGG 240 D L GYFEQEIK NYNTCIEE+W+EFPSFTQ+E+RAALAKCGLTT+HIESK+ VLSGG Sbjct: 385 DYLNIGYFEQEIKKANYNTCIEEVWSEFPSFTQYEVRAALAKCGLTTKHIESKVLVLSGG 444 Query: 241 EKAKVRLCKLINRETNLLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIV 300 E+AKVRLCKLIN+ETN LVLDEPTNHLDVDAK+EL+RA++AYKGS+LLI HEPEFY+DIV Sbjct: 445 EQAKVRLCKLINKETNFLVLDEPTNHLDVDAKEELKRAIKAYKGSVLLICHEPEFYQDIV 504 Query: 301 TDTWNCESWTTKV 313 TD WNCE+WTTK+ Sbjct: 505 TDVWNCENWTTKI 517 Score = 70.5 bits (171), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 95/232 (40%), Gaps = 44/232 (18%) Query: 121 IFETKDLVIGY-DSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARL 179 I ++L G+ D + ++ + +G+ I LVGANG GK++ + I G + G Sbjct: 3 ILSVENLTHGFGDRAIFNDVSFNLLKGEHIGLVGANGEGKSSFMNIITGNLEPDEGVIEW 62 Query: 180 GDLLETGYFEQEIKGTNYNTCIEEIWAEFPSFTQFE------------------------ 215 + GY +Q + T E + F E Sbjct: 63 SKRVRVGYLDQHTVLKSGTTIREFLKTAFKYLFDLEKEMNEICDKMGTANSDELELLLED 122 Query: 216 -------------------IRAALAKCGLTTQHIESKIAVLSGGEKAKVRLCKLINRETN 256 I G+ ++ + LSGG++ K+ L KL+ + + Sbjct: 123 MGTIQDILTNNDFYIIDAKIDEVARGMGIADIGLDKDVQDLSGGQRTKILLAKLLLEKPD 182 Query: 257 LLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIVTDTWNCES 308 +L+LDEPTN+LD + L+R LQ Y+ + +LISH+ F ++ ++ E+ Sbjct: 183 ILLLDEPTNYLDEQHIEWLKRYLQDYENAFILISHDIPFLNSVINLIYHMEN 234 >ref|NP_349931.1| ATPase component of ABC transporter (two ATPase domains) [Clostridium acetobutylicum] pir||D97310 ATPase component of ABC transporter (two ATPase domains) CAC3339 [imported] - Clostridium acetobutylicum gb|AAK81271.1| ATPase component of ABC transporter (two ATPase domains) [Clostridium acetobutylicum] Length = 518 Score = 517 bits (1331), Expect = e-145, Method: Compositional matrix adjust. Identities = 235/314 (74%), Positives = 277/314 (88%) Query: 1 LQEYENAFILISHDIPFLNSVINLIYHMENQSLTRYVGDYEYFQQVYEAKKSQLESAFKR 60 L ++ENAFILISHDIPFLNSVIN+IYH++N+ LTRY GDY+ F +VYEA K Q+E+A++R Sbjct: 205 LNDFENAFILISHDIPFLNSVINVIYHIDNRKLTRYAGDYDNFMRVYEANKKQVEAAYER 264 Query: 61 QQQEIADLKDFVARNKASVATRNMAMSRQKKLDKMEVIELAREKPKPQFNFKAGRTSGKL 120 QQQEIA LKDFVARNKA VAT MA +RQK+LDKM++IE +EKPKP+FNFK RTSGKL Sbjct: 265 QQQEIAKLKDFVARNKARVATTGMARARQKQLDKMDIIEKTQEKPKPEFNFKTARTSGKL 324 Query: 121 IFETKDLVIGYDSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARLG 180 IFETKDLV+GYDSPLS+PLNL MERGQKIALVGANG+GKTTLL+S+LG+I ISG LG Sbjct: 325 IFETKDLVVGYDSPLSKPLNLTMERGQKIALVGANGLGKTTLLKSLLGKIKPISGDVELG 384 Query: 181 DLLETGYFEQEIKGTNYNTCIEEIWAEFPSFTQFEIRAALAKCGLTTQHIESKIAVLSGG 240 D GYFEQEIK N TCIEE+W EFP++TQ+E+RAALAKCGLTT+HIESK+ VLSGG Sbjct: 385 DYQYIGYFEQEIKEANDKTCIEEVWEEFPAYTQYEVRAALAKCGLTTKHIESKVMVLSGG 444 Query: 241 EKAKVRLCKLINRETNLLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIV 300 E+AKVRLCKLIN ETN+L+LDEPTNHLDVDAKDEL+RAL+ Y+GSILL+ HEPEFY+D+V Sbjct: 445 EQAKVRLCKLINNETNILILDEPTNHLDVDAKDELKRALKEYRGSILLVCHEPEFYKDVV 504 Query: 301 TDTWNCESWTTKVF 314 TD WNCE WTTK++ Sbjct: 505 TDVWNCEEWTTKIY 518 Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 55/232 (23%), Positives = 108/232 (46%), Gaps = 44/232 (18%) Query: 121 IFETKDLVIGY-DSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARL 179 I K++ G+ D + ++ ++ +G+ + LVGANG GK+T + I G++ G+ Sbjct: 3 ILNVKNVNHGFGDRAIFEDVSFRLLKGEHVGLVGANGEGKSTFMSIITGKLMPDEGTIEW 62 Query: 180 GDLLETGYFEQEI---KGTNYNTCIE--------------EIWAEFPSFTQFEIRAALAK 222 + + GY +Q KG ++ EI + ++ E++ L + Sbjct: 63 SNNVRVGYMDQHASLQKGKTIKDVLKDAFKYLFDMEANMMEITDKMAEASEDELQKLLDE 122 Query: 223 --------------------------CGLTTQHIESKIAVLSGGEKAKVRLCKLINRETN 256 G+T ++ +A LSGG++ KV L KL+ ++ + Sbjct: 123 MGTIQDTLDNNDFYVIDVKIEEVAKGLGITDIGLDKDVADLSGGQRTKVLLAKLLLQKPD 182 Query: 257 LLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIVTDTWNCES 308 +L+LDEPTN+LD + L+R L ++ + +LISH+ F ++ ++ ++ Sbjct: 183 ILLLDEPTNYLDEVHIEWLKRYLNDFENAFILISHDIPFLNSVINVIYHIDN 234 >ref|NP_561053.1| probable ABC transporter [Clostridium perfringens] dbj|BAB79843.1| probable ABC transporter [Clostridium perfringens str. 13] Length = 518 Score = 513 bits (1322), Expect = e-144, Method: Compositional matrix adjust. Identities = 233/310 (75%), Positives = 274/310 (88%) Query: 4 YENAFILISHDIPFLNSVINLIYHMENQSLTRYVGDYEYFQQVYEAKKSQLESAFKRQQQ 63 YENAFILISHDIPFLNSV+N+IYH+EN++LTRY GDY+ F +VYEA K QLE+A++RQQ Sbjct: 208 YENAFILISHDIPFLNSVVNVIYHVENRALTRYTGDYDNFMRVYEANKKQLEAAYERQQA 267 Query: 64 EIADLKDFVARNKASVATRNMAMSRQKKLDKMEVIELAREKPKPQFNFKAGRTSGKLIFE 123 EIA L+DFVARNKA VAT MA +RQKKLDKM+ IELA EKPKP+FNFK GRTSGKLIFE Sbjct: 268 EIAKLEDFVARNKARVATTGMARARQKKLDKMDRIELAAEKPKPEFNFKQGRTSGKLIFE 327 Query: 124 TKDLVIGYDSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARLGDLL 183 +DLVIGYD PLS+PLN++MERGQKIALVGANG+GK+TLL+S++G I ISG GD Sbjct: 328 ARDLVIGYDEPLSKPLNIRMERGQKIALVGANGLGKSTLLKSLMGLIKPISGEVETGDYQ 387 Query: 184 ETGYFEQEIKGTNYNTCIEEIWAEFPSFTQFEIRAALAKCGLTTQHIESKIAVLSGGEKA 243 GYFEQEIK NYN+CIEE+W EFP +TQ+E+R+ALAKCGLTT+HIES +AVLSGGE+A Sbjct: 388 SIGYFEQEIKEANYNSCIEEVWQEFPGYTQYEVRSALAKCGLTTKHIESSVAVLSGGEQA 447 Query: 244 KVRLCKLINRETNLLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIVTDT 303 KVRLCKLIN+ETN+L+LDEPTNHLDV+AKDEL+RAL+ YKGSILL+ HEPEFYRD+VTD Sbjct: 448 KVRLCKLINKETNILILDEPTNHLDVEAKDELKRALKEYKGSILLVCHEPEFYRDVVTDV 507 Query: 304 WNCESWTTKV 313 WNCE WTTK+ Sbjct: 508 WNCEEWTTKI 517 Score = 73.2 bits (178), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 56/232 (24%), Positives = 102/232 (43%), Gaps = 44/232 (18%) Query: 121 IFETKDLVIGY-DSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARL 179 I K++ G+ D + ++ ++ +G+ + L+GANG GK+T + I G++ G + Sbjct: 3 ILIVKNMNHGFGDRAIFEDVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGDVQW 62 Query: 180 GDLLETGYFEQEI---KGTNYNTCIEE--------------IWAEFPSFTQFEIRAAL-- 220 + + GY +Q KG + E ++ ++ E+ AL Sbjct: 63 SNKVRVGYMDQHAQLEKGKTIREVLREAFQYLFDMEVEMNGLYERMGEMSEDEMTKALER 122 Query: 221 ------------------------AKCGLTTQHIESKIAVLSGGEKAKVRLCKLINRETN 256 A GL ++ + LSGG++ KV L KL+ + Sbjct: 123 TATIQDMLDHNGFYMIDAKVEEVAAGLGLRDVGLDKDVTDLSGGQRTKVLLAKLLLETPD 182 Query: 257 LLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIVTDTWNCES 308 +L+LDEPTN+LD + L+ L Y+ + +LISH+ F +V ++ E+ Sbjct: 183 ILLLDEPTNYLDEEHIAWLKNYLIGYENAFILISHDIPFLNSVVNVIYHVEN 234 >ref|NP_345268.1| ABC transporter, ATP-binding protein [Streptococcus pneumoniae TIGR4] pir||C95089 ABC transporter, ATP-binding protein SP0770 [imported] - Streptococcus pneumoniae (strain TIGR4) gb|AAK74908.1| ABC transporter, ATP-binding protein [Streptococcus pneumoniae TIGR4] Length = 513 Score = 456 bits (1174), Expect = e-127, Method: Compositional matrix adjust. Identities = 210/310 (67%), Positives = 254/310 (81%) Query: 1 LQEYENAFILISHDIPFLNSVINLIYHMENQSLTRYVGDYEYFQQVYEAKKSQLESAFKR 60 LQ YENAF+LISHDIPFLN VIN++YH+ENQ LTRY GDY FQ+VY KKSQLE+A++R Sbjct: 204 LQNYENAFVLISHDIPFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYER 263 Query: 61 QQQEIADLKDFVARNKASVATRNMAMSRQKKLDKMEVIELAREKPKPQFNFKAGRTSGKL 120 QQ+EIADLKDFVARNKA VATRNMAMSRQKKLDKM++IEL EKPKP F+FK RT G+ Sbjct: 264 QQKEIADLKDFVARNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRF 323 Query: 121 IFETKDLVIGYDSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARLG 180 IF+ K+L IGYD PL++PLNL ER QK+A++GANGIGKTTLL+S+LG I I+G G Sbjct: 324 IFQAKNLQIGYDRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERG 383 Query: 181 DLLETGYFEQEIKGTNYNTCIEEIWAEFPSFTQFEIRAALAKCGLTTQHIESKIAVLSGG 240 D LE GYFEQE++G N T +E +W FP+ Q E+RAALA+CGLTT+HIES+I VLSGG Sbjct: 384 DYLELGYFEQEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGG 443 Query: 241 EKAKVRLCKLINRETNLLVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIV 300 E+AKVR C L+NRE N+LVLDEPTNHLDVDAKDEL+RAL+ Y+GSIL++ HEP+FY + Sbjct: 444 EQAKVRFCLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWI 503 Query: 301 TDTWNCESWT 310 W+ + T Sbjct: 504 DQIWDFNNLT 513 Score = 86.7 bits (213), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 60/231 (25%), Positives = 105/231 (45%), Gaps = 43/231 (18%) Query: 121 IFETKDLVIGY-DSPLSRPLNLQMERGQKIALVGANGIGKTTLLRSILGQIPAISGSARL 179 I E K+L G+ D + ++ ++ +G+ I LVGANG GK+T + + G++ G Sbjct: 3 ILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKSTFMSIVTGKMLPDEGKVEW 62 Query: 180 GDLLETGYFEQEI-----------------------------------KGTNYNTCIEEI 204 + GY +Q G + + +EE+ Sbjct: 63 SKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARINDLYMKMAEDGADVDALMEEV 122 Query: 205 WA-----EFPSFTQFE--IRAALAKCGLTTQHIESKIAVLSGGEKAKVRLCKLINRETNL 257 E F + I G+ +++ + LSGG++ KV L KL+ + ++ Sbjct: 123 GELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVTSLSGGQRTKVLLAKLLLEKPDI 182 Query: 258 LVLDEPTNHLDVDAKDELQRALQAYKGSILLISHEPEFYRDIVTDTWNCES 308 L+LDEPTN+LD + D L+R LQ Y+ + +LISH+ F D++ ++ E+ Sbjct: 183 LLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDIPFLNDVINIVYHVEN 233 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.134 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 436,748,171 Number of extensions: 17167648 Number of successful extensions: 129164 Number of sequences better than 1.0e-05: 3179 Number of HSP's gapped: 128472 Number of HSP's successfully gapped: 3878 Length of query: 314 Length of database: 757,237,578 Length adjustment: 125 Effective length of query: 189 Effective length of database: 417,850,203 Effective search space: 78973688367 Effective search space used: 78973688367 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)