BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0046.p (444 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_244709.1| two-component response regulator [Bacillus halo... 197 5e-49 ref|NP_621980.1| CheY-like receiver domains [Thermoanaerobacter ... 114 5e-24 ref|ZP_00180754.1| hypothetical protein Mther123301 [Moorella th... 103 7e-21 ref|ZP_00036570.1| COG4753: Response regulator containing CheY-l... 97 7e-19 ref|NP_792514.1| transcriptional activator MltR [Pseudomonas syr... 96 2e-18 >ref|NP_244709.1| two-component response regulator [Bacillus halodurans] pir||B84130 two-component response regulator BH3842 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07561.1| two-component response regulator [Bacillus halodurans] Length = 530 Score = 197 bits (501), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 153/522 (29%), Positives = 250/522 (47%), Gaps = 90/522 (17%) Query: 1 MYRLLIADDEPLEREGLELTVERSMPGIFRFIHAGNGRKAIECAEEHRPHIVILDINMPG 60 M +LI DDE +EREGL+L + + P I A NGR+AIE A E +P ++++DI MPG Sbjct: 1 MINVLIVDDEQIEREGLKLFL-KDRPNIHIVGEASNGRQAIEKALETQPDLMMMDIKMPG 59 Query: 61 IXXXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKR 120 + T ++V+A+D F YA+E + G KEY+LKP +E ++ L R Sbjct: 60 VDGVQAVKEIKQQLPETEF--IMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDR 117 Query: 121 LISEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQ 180 ++ EIE+ ++ + ++ +L+ ++ Q+ V+ E L L++D D + +EWL + Sbjct: 118 IVGEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEWMEWNEWLRTE-QE 176 Query: 181 GSAIVVAFEGHPS---LQEKKKIYDHFRSFVKIHSSASIVSSLIDHHLVIFVRKPLSMGE 237 G A+V +F EK++ + + + + S V I HHL I + L+ E Sbjct: 177 GYAVVFSFHQQGKEIRKTEKQQWHARIKKEIGLQLPKSTVGPFIGHHLPILM---LTENE 233 Query: 238 NDW--RERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFA-STLQEHG 294 N +ER + + + L ++ + G+G + R F SY EA+ A + +H Sbjct: 234 NGMTKQEREQVVIQLLHKVKQAVQPAKVKTGVGGIYRL-HFFSTSYREALLALDIIYDHK 292 Query: 295 EAYSHF---------------EELKRIGSPHDPGPISTAPQ------QSYVISALHRIRE 333 +A +F E ++ G A Q Q+ + + H + + Sbjct: 293 QASYYFYDKNVKIRADEQLPIERENKLIEAIKSGDGEKALQAFDHYVQAILRCSKHPLHD 352 Query: 334 QRE--EQTLTVLGRAKKYIG-----------------------------------ERYTD 356 R+ +Q +LGR +G R TD Sbjct: 353 MRKYLQQLFIILGRLLNEMGLHWETAQDFARFSTVHQVTEHGKSEILHIVRTLQEWRTTD 412 Query: 357 DLSLEEVA-DYVH-----------------LNPHYFSKIFKQEYGETFIDFVTRLRIDKA 398 + SL +A DYVH L+P+Y SK+FK+ + TF ++VT+LR++ A Sbjct: 413 EQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEHA 472 Query: 399 ISLIGEGRLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFR 440 L+ + SLKE+++E GYKDPNYFSRVFKK+TG SP+++R Sbjct: 473 KQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYR 514 >ref|NP_621980.1| CheY-like receiver domains [Thermoanaerobacter tengcongensis] gb|AAM23584.1| CheY-like receiver domains [Thermoanaerobacter tengcongensis] Length = 529 Score = 114 bits (285), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 51/113 (45%), Positives = 80/113 (70%) Query: 328 LHRIREQREEQTLTVLGRAKKYIGERYTDDLSLEEVADYVHLNPHYFSKIFKQEYGETFI 387 + IR +++ + + ++ E ++ D+SLE+ A V+++ HYFSK FK++ GE F+ Sbjct: 414 VENIRVVNKKKWDNITMKVINFLEENFSKDISLEDAAREVNMSYHYFSKFFKEQVGENFV 473 Query: 388 DFVTRLRIDKAISLIGEGRLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFR 440 D++T LRI KA L+ LS+KEVS++ GY DPNYFS++FKK+TGV+PTEF+ Sbjct: 474 DYLTNLRIRKAKELLKNSSLSVKEVSYKVGYSDPNYFSKIFKKVTGVTPTEFK 526 Score = 103 bits (257), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 86/331 (25%), Positives = 151/331 (45%), Gaps = 26/331 (7%) Query: 1 MYRLLIADDEPLEREGLELTVERSMPGIFRFIHAGNGRKAIECAEEHRPHIVILDINMPG 60 M +LLIADDE + + ++ +E++ A +GR+AIE A+ +P ++ +DI MPG Sbjct: 1 MVKLLIADDEQIVLDSIKFIIEKNNVQAEIVGTAKSGREAIEKADLLKPDLIFMDIRMPG 60 Query: 61 IXXXXXXXXXXXXXXXTXXXXVLVTAYDYFAYAQEALSLGAKEYILKPAKREQIIGTLKR 120 I V++TAY+YF YA+EA+ LG +Y+LKP + +II +++ Sbjct: 61 IDGIEAIRQIKERHKEMIF--VIITAYEYFNYAKEAIDLGVMDYLLKPLNKNKIIEVIEK 118 Query: 121 LISEIEREKQLRAEELELRHKMSQLLPLVENELALILMVDQTADSTASQLSEWLDFPLDQ 180 IE ++ E+ELR K+++++P +E + ++ + E D L++ Sbjct: 119 ASKVIEERRKAVLTEIELREKINKIMPYLEEQFLYTVLFGGYVGGSLDFYEEIFDMKLEK 178 Query: 181 GSAIVVAFEGHPSLQEKKKI---------YDHFRSFVKIHSSASIVSSLIDHHLVIFV-- 229 G ++ S + +K I Y+H R F+K S + +D V F Sbjct: 179 GYIMIFLMRSDTSNEREKSIEVNLKRQSLYEHLRIFLKGVSKCILGPFFMDKICVYFPVE 238 Query: 230 -RKPLSMGENDWRERNKEIARQLFELASQQTGIQAAVGIGSLRRGEEGFRESYFEAVFAS 288 + P + + + +IA ++ E VGIG +SY+EA A Sbjct: 239 EKTPFEV-----KNSSVKIANKVLESLQGSEKENLRVGIGR-EYSFNNIVKSYYEAEMAL 292 Query: 289 TLQEHGEAYSHFEELKRIGS---PHDPGPIS 316 L + HF++ +G+ H P P+ Sbjct: 293 KLFPD-DTIVHFDD--AVGTSTISHFPYPLD 320 >ref|ZP_00180754.1| hypothetical protein Mther123301 [Moorella thermoacetica ATCC 39073] Length = 439 Score = 103 bits (258), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 48/117 (41%), Positives = 79/117 (67%) Query: 324 VISALHRIREQREEQTLTVLGRAKKYIGERYTDDLSLEEVADYVHLNPHYFSKIFKQEYG 383 +++ + ++ E RE++ +++ RA KYI ++ DL+LEEVA V+L+P YFSK+FKQ G Sbjct: 311 LMALVAQVAETREQRNSSLIDRASKYIEANFSQDLTLEEVARQVYLSPCYFSKLFKQFKG 370 Query: 384 ETFIDFVTRLRIDKAISLIGEGRLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFR 440 FID++T++R+ A L+ +L + E++ GY+D YF +VFKK G +P+ FR Sbjct: 371 LNFIDYLTKVRLKAARELLLNTKLPVAEIATRVGYRDARYFGQVFKKQEGYTPSVFR 427 >ref|ZP_00036570.1| COG4753: Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Enterococcus faecium] Length = 521 Score = 97.1 bits (240), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 46/102 (45%), Positives = 67/102 (65%), Gaps = 1/102 (0%) Query: 342 VLGRAKKYIGERYTD-DLSLEEVADYVHLNPHYFSKIFKQEYGETFIDFVTRLRIDKAIS 400 +L A +I E +TD D+SL VA V L+P +FS IF Q + +TFID++T RI+ A Sbjct: 412 ILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFSQSFNQTFIDYLTEQRIELAKK 471 Query: 401 LIGEGRLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFRGK 442 L+ + + +++FE GY DPNYFS +FKK G+SP E+R + Sbjct: 472 LLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPKEYRTQ 513 >ref|NP_792514.1| transcriptional activator MltR [Pseudomonas syringae pv. tomato str. DC3000] gb|AAO56209.1| transcriptional activator MltR [Pseudomonas syringae pv. tomato str. DC3000] Length = 301 Score = 95.9 bits (237), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 41/105 (39%), Positives = 71/105 (67%) Query: 336 EEQTLTVLGRAKKYIGERYTDDLSLEEVADYVHLNPHYFSKIFKQEYGETFIDFVTRLRI 395 +E ++ RA YI Y+ +L LEEVA+Y+ + P YFS++FKQ G F++FV RLRI Sbjct: 184 DEHSVDRTNRAVDYIFAHYSRELPLEEVAEYLGMKPTYFSRVFKQATGRCFVEFVNRLRI 243 Query: 396 DKAISLIGEGRLSLKEVSFEAGYKDPNYFSRVFKKITGVSPTEFR 440 K+ L+ +G ++ +V FE+G+ + + F+R F+++ G++P+ +R Sbjct: 244 SKSCELLADGDKTVTDVCFESGFNNISNFNRRFQQLKGMTPSHYR 288 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 600,207,483 Number of extensions: 23205265 Number of successful extensions: 81892 Number of sequences better than 1.0e-05: 663 Number of HSP's gapped: 83155 Number of HSP's successfully gapped: 694 Length of query: 444 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 315 Effective length of database: 406,989,807 Effective search space: 128201789205 Effective search space used: 128201789205 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 127 (53.5 bits)