BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0041.p (461 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_466105.1| similar to two-component sensor histidine kinas... 243 1e-62 ref|NP_845559.1| sensor histidine kinase [Bacillus anthracis str... 240 6e-62 ref|NP_472056.1| similar to two-component sensor histidine kinas... 239 7e-62 ref|NP_979572.1| sensor histidine kinase [Bacillus cereus ATCC 1... 239 7e-62 ref|NP_832968.1| Two component system histidine kinase [Bacillus... 239 8e-62 >ref|NP_466105.1| similar to two-component sensor histidine kinase [Listeria monocytogenes EGD-e] pir||AF1397 two-component sensor histidine kinase homolog lmo2582 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAD00660.1| lmo2582 [Listeria monocytogenes] Length = 459 Score = 243 bits (619), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 151/466 (32%), Positives = 234/466 (50%), Gaps = 23/466 (4%) Query: 1 MKTLYVRVVLTFXXXXXXXXXXXXXXXXXXFQKGLNATGKNDMIAAGNRIIRVYEQTNPP 60 MK+LY R+V+T +Q L + + YE Sbjct: 1 MKSLYSRIVVTMLVVILSSSLLGFFFANIYYQIKLKLFNDEKTAKIAKEVQQFYESNATI 60 Query: 61 DLDTFMDNMAELVSYTLQLYEGNGGVDSYVPAKGRQAGKISPESVRIVLQGEVYRS-QGQ 119 L+ +++N+ EL +LY +G S + + ++++ VL G+ Y Sbjct: 61 SLNEYLENVGEL---GYELYLTDGAEKSTYFGGAFRKKDLPDKTIKQVLDGDTYHGIDSF 117 Query: 120 DNGTFI------------GLPFVSEGKRYALFVQSSSKNEX-XXXXXXXXXXXXXXXXXX 166 D G FI G+P +GK+ ALF++ + + Sbjct: 118 DTGIFITGFFDNDVRNTIGVPVQVDGKQLALFIRQDPEQQFGELRIFFAMILIFTSIISI 177 Query: 167 XXXXVAGRYVVKPLQAMTDATKRLAKGDFEVELKINRGDELGTLSRSINDMAREIRQMER 226 ++GRY+V P+ +T+ATK++ KG+++V ++ R DE+G L+ S MA E+ + E Sbjct: 178 LFVLISGRYIVNPVVKLTNATKKIRKGNYDVAFEVRRKDEIGQLADSFTKMASELEKSEA 237 Query: 227 MRQDFVSNVSHEIQSPLTSISGFAKALKDGDLVIGEDERVQYLDIIVTEXXXXXXXXXXX 286 RQ+FV+NVSHE+QSPLTS+ GFA+ L G L E E+ +YL ++ E Sbjct: 238 ARQEFVANVSHELQSPLTSMQGFARLLGSGTLT--EKEQAEYLTVLSEETTRLSSLTKQL 295 Query: 287 XXXASLESEHHPFQTETYNLDEQLRRVIVACEPLWSAKDIRVDMESPSGAAVRITADKDQ 346 ASL+ E + E +L +Q R++I E W K++ ++++ A V T D + Sbjct: 296 LTLASLDQESELRKKEPVHLAKQWRQLIQMTEWSWREKELTINLDL---ADVNYTGDAEL 352 Query: 347 LNQVWMNLLGNAVKFTPCARQVLIAISQPQPGEVAVAVSDSGIGIAPEDTGFIFERFYKA 406 L QVW NLL NA+KFTP + + + + V V V DSG+GI+ D IF+RFYKA Sbjct: 353 LYQVWSNLLTNAIKFTPQGGNIQVRLYEDTTN-VFVEVQDSGVGISKVDMTKIFDRFYKA 411 Query: 407 DKSRAEDRSGNGLGLAISQKIVALHHGSIAVKSTAGLGTTFTVTLP 452 ++SR + +GLGL+I QKI+ LHHG + V+S+ GTTFTV LP Sbjct: 412 NESRTREEGSSGLGLSICQKIITLHHGEVTVQSSLEKGTTFTVKLP 457 >ref|NP_845559.1| sensor histidine kinase [Bacillus anthracis str. Ames] gb|AAP27045.1| sensor histidine kinase [Bacillus anthracis str. Ames] Length = 458 Score = 240 bits (612), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 148/475 (31%), Positives = 242/475 (50%), Gaps = 41/475 (8%) Query: 1 MKTLYVRVVLTFXXXXXXXXXXXXXXXXXXFQKGLNATGKNDMIAAGNRIIRVYEQTNPP 60 MK+LY R V +Q L ++ + +YE+ + Sbjct: 1 MKSLYSRFVFMTVGIMLLSSIIGFLLTNVYYQVKLKPYNSEKILKYAEEVKSLYEKQSEE 60 Query: 61 DLDTFMDNMAELVSYTLQLYEGNGGVDSYV---PAKGRQAGK------ISPESVRIVLQG 111 + + ++ ++A+L G + Y+ G++ G IS +++R VL G Sbjct: 61 NQEAYLQSIAKL------------GYEIYIVDDQKNGKRIGNAFRKTTISDDTIRKVLNG 108 Query: 112 EV------YRSQGQDNGTF-------IGLPFVSEGKRYALFVQSSSKNEXXXXXXXXXXX 158 E Y ++ G F +G+P K+YALF++ +N+ Sbjct: 109 ETFNGVSTYPTRLFITGFFDNELINSVGVPLKHGDKQYALFIRPDIQNQFGEMRIFLAVL 168 Query: 159 X-XXXXXXXXXXXVAGRYVVKPLQAMTDATKRLAKGDFEVELKINRGDELGTLSRSINDM 217 +A Y+V+P++ T+AT+++A G++E+EL + R DE+GTLS S M Sbjct: 169 LGFIVLLSIIFIAIAAGYIVRPIRKFTNATQKIASGEYEIELDVKRKDEIGTLSTSFQKM 228 Query: 218 AREIRQMERMRQDFVSNVSHEIQSPLTSISGFAKALKDGDLVIGEDERVQYLDIIVTEXX 277 + I++++ MRQ+FVSNVSHE QSPL+SI GF+K L+ + + +ER YL II E Sbjct: 229 TKSIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSV--EERNHYLQIIEGESK 286 Query: 278 XXXXXXXXXXXXASLESEHHPFQTETYNLDEQLRRVIVACEPLWSAKDIRVDMESPSGAA 337 ASL+ E Q + +NL +Q++ VI E W K+I ++ + P Sbjct: 287 RMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKDVIFMLEWKWREKNIAIEFDVPD--- 343 Query: 338 VRITADKDQLNQVWMNLLGNAVKFTPCARQVLIAISQPQPGEVAVAVSDSGIGIAPEDTG 397 + I D++ L+QVW N+ N++KF+ + + + + V +++SD+GIG+ E+ Sbjct: 344 ITIKGDENLLHQVWSNIFTNSIKFSNEGGTIEFFVEELESS-VIISISDNGIGMEKEEMD 402 Query: 398 FIFERFYKADKSRAEDRSGNGLGLAISQKIVALHHGSIAVKSTAGLGTTFTVTLP 452 IF+RFYK D +RA + G+GLGL+I QKIV LH+G+++V ST G GTT V LP Sbjct: 403 RIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457 >ref|NP_472056.1| similar to two-component sensor histidine kinase [Listeria innocua] pir||AI1772 two-component sensor histidine kinase homolog lin2727 [imported] - Listeria innocua (strain Clip11262) emb|CAC97953.1| lin2727 [Listeria innocua] Length = 459 Score = 239 bits (611), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 153/466 (32%), Positives = 235/466 (50%), Gaps = 23/466 (4%) Query: 1 MKTLYVRVVLTFXXXXXXXXXXXXXXXXXXFQKGLNATGKNDMIAAGNRIIRVYEQTNPP 60 MK+LY R+V+T +Q L + + Y+ Sbjct: 1 MKSLYSRIVVTMLVVILSSSLLGFFFANIYYQIKLKPFNDEKTAKIAEEVQQFYQSNRAI 60 Query: 61 DLDTFMDNMAELVSYTLQLYEGNGGVDSYVPAKGRQAGKISPESVRIVLQGEVYRS-QGQ 119 L +++N+ EL Y L L +G SY R+ + ++V+ VL GE Y Sbjct: 61 SLKEYLENVGEL-GYELYLTDGKDQ-SSYFGGAFRKKD-LPNKTVQQVLAGETYHGIDTF 117 Query: 120 DNGTFI------------GLPFVSEGKRYALFVQSSSKNEX-XXXXXXXXXXXXXXXXXX 166 D G FI G+P ++G++ ALF++ + + Sbjct: 118 DTGIFITGFFDNDVRNTIGVPVKADGEQLALFIRQDPEQQFGELRIFFAMILVFTSIISI 177 Query: 167 XXXXVAGRYVVKPLQAMTDATKRLAKGDFEVELKINRGDELGTLSRSINDMAREIRQMER 226 ++GRY+VKP+ +T+ATK++ +G+++V L++ R DE+G L+ S MA E+ + E Sbjct: 178 LFVLISGRYIVKPVVKLTNATKKIRRGNYDVALEVRRKDEIGQLADSFAKMASELEKSEA 237 Query: 227 MRQDFVSNVSHEIQSPLTSISGFAKALKDGDLVIGEDERVQYLDIIVTEXXXXXXXXXXX 286 RQ+FV+NVSHE+QSPLTS+ GFA+ L G L E E+ +YL ++ E Sbjct: 238 ARQEFVANVSHELQSPLTSMQGFARLLGSGTLT--EKEQKEYLTVLSEETTRLSSLTKQL 295 Query: 287 XXXASLESEHHPFQTETYNLDEQLRRVIVACEPLWSAKDIRVDMESPSGAAVRITADKDQ 346 ASL+ E + E L EQ R++I E W K++ +++E A + + D + Sbjct: 296 LTLASLDQESELRKKEPVQLAEQWRQLIQMTEWSWREKELTINLEL---ADINYSGDAEL 352 Query: 347 LNQVWMNLLGNAVKFTPCARQVLIAISQPQPGEVAVAVSDSGIGIAPEDTGFIFERFYKA 406 L QVW NLL NA+K+TP + + + + + V V V +SG GI+ ED IF+RFYKA Sbjct: 353 LYQVWSNLLNNAIKYTPLGGNIQVRLYE-ETTNVFVEVWNSGAGISKEDMAKIFDRFYKA 411 Query: 407 DKSRAEDRSGNGLGLAISQKIVALHHGSIAVKSTAGLGTTFTVTLP 452 +SR + +GLGL+I +KI+ LHHG I V+S GTTF V LP Sbjct: 412 SQSRTREEGSSGLGLSICKKIITLHHGEITVESNTDKGTTFKVKLP 457 >ref|NP_979572.1| sensor histidine kinase [Bacillus cereus ATCC 10987] gb|AAS42180.1| sensor histidine kinase [Bacillus cereus ATCC 10987] Length = 458 Score = 239 bits (611), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 151/475 (31%), Positives = 241/475 (50%), Gaps = 41/475 (8%) Query: 1 MKTLYVRVVLTFXXXXXXXXXXXXXXXXXXFQKGLNATGKNDMIAAGNRIIRVYEQTNPP 60 MK+LY R V +Q L ++ + +YE+ + Sbjct: 1 MKSLYSRFVFMTVGIMLLSSIIGFLLTNVYYQVKLKPYNSEKILKYAEEVKSLYEKQSEE 60 Query: 61 DLDTFMDNMAELVSYTLQLYEGNGGVDSYV---PAKGRQAGK------ISPESVRIVLQG 111 + + ++ ++A+L G + Y+ G++ G IS ++V VLQG Sbjct: 61 NQEAYLQSIAKL------------GYEIYIVDDQKNGKRIGNAFRKTSISDDTVHKVLQG 108 Query: 112 EV------YRSQGQDNGTF-------IGLPFVSEGKRYALFVQSSSKNEXXXXXXXXXXX 158 E Y ++ G F +G+P K+YALF++ +N+ Sbjct: 109 ETFNGVSTYPTRLFITGFFDNELINSVGVPVKHGDKQYALFIRPDIQNQFGEMRIFLAVL 168 Query: 159 X-XXXXXXXXXXXVAGRYVVKPLQAMTDATKRLAKGDFEVELKINRGDELGTLSRSINDM 217 +A Y+V+P++ T AT+++A G++E+EL + R DE+GTLS S M Sbjct: 169 LGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYEIELDVKRKDEIGTLSTSFQKM 228 Query: 218 AREIRQMERMRQDFVSNVSHEIQSPLTSISGFAKALKDGDLVIGEDERVQYLDIIVTEXX 277 + I++++ MRQ+FVSNVSHE QSPL+SI GF+K L+ + + +ER YL II E Sbjct: 229 TKSIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKMSM--EERNHYLQIIEGESK 286 Query: 278 XXXXXXXXXXXXASLESEHHPFQTETYNLDEQLRRVIVACEPLWSAKDIRVDMESPSGAA 337 ASL+ E Q + +NL +Q++ VI E W KDI V+ + P Sbjct: 287 RMSSLCKQLLTLASLDKEEKVLQIKEFNLQKQIKDVIFMLEWKWREKDIAVEFDVPD--- 343 Query: 338 VRITADKDQLNQVWMNLLGNAVKFTPCARQVLIAISQPQPGEVAVAVSDSGIGIAPEDTG 397 + I D++ L+QVW N+ N++KF+ + + + + V +++SD+GIG+ E+ Sbjct: 344 IVIKGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESS-VIISISDNGIGMEQEEMD 402 Query: 398 FIFERFYKADKSRAEDRSGNGLGLAISQKIVALHHGSIAVKSTAGLGTTFTVTLP 452 IF+RFYK D +RA + G+GLGL+I QKIV LH+G+++V ST G GTT V LP Sbjct: 403 RIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHNGNVSVYSTKGEGTTVRVELP 457 >ref|NP_832968.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] gb|AAP10169.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] Length = 458 Score = 239 bits (611), Expect = 8e-62, Method: Compositional matrix adjust. Identities = 151/475 (31%), Positives = 240/475 (50%), Gaps = 41/475 (8%) Query: 1 MKTLYVRVVLTFXXXXXXXXXXXXXXXXXXFQKGLNATGKNDMIAAGNRIIRVYEQTNPP 60 MK+LY R V +Q L ++ + +YE+ + Sbjct: 1 MKSLYSRFVFMTVGIMLLSSIIGFLLTNVYYQVKLKPYNSEKILKYAEEVKSLYEKQSEE 60 Query: 61 DLDTFMDNMAELVSYTLQLYEGNGGVDSYV---PAKGRQAGK------ISPESVRIVLQG 111 + +T++ ++A+L G + Y+ G++ G IS +V VLQG Sbjct: 61 NQETYLHSIAKL------------GYEIYIVDDQKNGKRIGNAFRKTSISDATVHKVLQG 108 Query: 112 EV------YRSQGQDNGTF-------IGLPFVSEGKRYALFVQSSSKNEXXXXXXXXXXX 158 E Y ++ G F +G+P K+YALF++ +N+ Sbjct: 109 ETFNGVSTYPTRLFITGFFDNELINSVGVPVKHGDKQYALFIRPDIQNQFGEMRIFLAVL 168 Query: 159 X-XXXXXXXXXXXVAGRYVVKPLQAMTDATKRLAKGDFEVELKINRGDELGTLSRSINDM 217 +A Y+V+P++ T AT+++A G++++EL + R DE+GTLS S M Sbjct: 169 LGFIVLLSIIFIAIAAGYIVRPIRKFTKATQKIASGEYKIELDVKRKDEIGTLSTSFQKM 228 Query: 218 AREIRQMERMRQDFVSNVSHEIQSPLTSISGFAKALKDGDLVIGEDERVQYLDIIVTEXX 277 + I++++ MRQ+FVSNVSHE QSPL+SI GF+K L+ + E+ER YL II E Sbjct: 229 TKSIKELDEMRQEFVSNVSHEFQSPLSSIQGFSKTLQTEKM--SEEERNHYLQIIEGESK 286 Query: 278 XXXXXXXXXXXXASLESEHHPFQTETYNLDEQLRRVIVACEPLWSAKDIRVDMESPSGAA 337 ASL+ E Q + ++L +Q++ VI E W KDI V+ + P Sbjct: 287 RMSSLCKQLLTLASLDKEEKVLQIKDFSLQKQIKDVIFMLEWKWREKDIAVEFDVPD--- 343 Query: 338 VRITADKDQLNQVWMNLLGNAVKFTPCARQVLIAISQPQPGEVAVAVSDSGIGIAPEDTG 397 + I D++ L+QVW N+ N++KF+ + + + + V +++SD+GIG+ E+ Sbjct: 344 ITIQGDENLLHQVWSNIFTNSIKFSNDGGTIEFFVEELESS-VIISISDNGIGMEKEEMD 402 Query: 398 FIFERFYKADKSRAEDRSGNGLGLAISQKIVALHHGSIAVKSTAGLGTTFTVTLP 452 IF+RFYK D +RA + G+GLGL+I QKIV LH G+++V ST G GTT V LP Sbjct: 403 RIFDRFYKVDTARARNVEGSGLGLSIVQKIVELHKGTVSVYSTKGEGTTVRVELP 457 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 570,227,656 Number of extensions: 21858212 Number of successful extensions: 74766 Number of sequences better than 1.0e-05: 4444 Number of HSP's gapped: 68922 Number of HSP's successfully gapped: 4476 Length of query: 461 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 332 Effective length of database: 406,989,807 Effective search space: 135120615924 Effective search space used: 135120615924 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 128 (53.9 bits)