BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0025.p (614 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_388576.1| similar to two-component sensor histidine kinas... 161 6e-38 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 149 1e-34 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 142 2e-32 ref|NP_691698.1| hypothetical protein OB0777 [Oceanobacillus ihe... 139 2e-31 ref|NP_244545.1| two-component sensor histidine kinase [Bacillus... 139 2e-31 >ref|NP_388576.1| similar to two-component sensor histidine kinase [YesN] [Bacillus subtilis] pir||D69796 two-component sensor histidine kinase homolog yesM - Bacillus subtilis emb|CAB12514.1| yesM [Bacillus subtilis subsp. subtilis str. 168] Length = 577 Score = 161 bits (407), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 102/335 (30%), Positives = 164/335 (48%), Gaps = 25/335 (7%) Query: 273 QKYLVMYDISQKEGWKLVKPIPYKQIYEAATTTRKLSYXXXXXXXXXXXXXXXXXXNRIT 332 ++Y + Y S + W IP+ Q++ + + + N IT Sbjct: 256 KRYFISYLQSSYQNWSYYNVIPFDQMFAKISFMKTVIGTCFLLFFCVVLLFGRKIANSIT 315 Query: 333 NPLKNLSLQMKRFSTGSFDAEAAVD----GNDEIAYLSRHFNKMVEKTNELINERYKMKI 388 P++ L MK +A ++ DE L+RHF M+++ NEL+ E + ++ Sbjct: 316 EPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDEAGMLNRHFTVMMKRINELMEENVEKQL 375 Query: 389 VEKNAVLKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCIS-GRDVV 447 + K LKAL+A+INPHFLYN L++I+ A N I +MV++L LR I +D+V Sbjct: 376 IIKETELKALQAQINPHFLYNTLESINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIV 435 Query: 448 QAREELKHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHALEKVS 507 +EE + Y+ +Q+ RF R++ D +D + IPKL++Q L EN I++ALE + Sbjct: 436 TIQEEADIVRHYMTIQRFRFEERLKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEPFT 495 Query: 508 STVTIRIEAHITAAHSVISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXXXXXXSIG 567 IRI+A I+V D+GPG+ + L+ IG Sbjct: 496 RPCAIRIQAKKAKGCVCITVEDNGPGMDGRILEST-------------------GGRGIG 536 Query: 568 LKNLNTRLKLLYGEEAGLVI-AGNEQGTRIDMRLP 601 L N+ R+ L +GE GL I + +E+GTRI + +P Sbjct: 537 LWNIRERISLTFGEPYGLRIHSEHEKGTRIVITIP 571 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 149 bits (377), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 92/275 (33%), Positives = 154/275 (56%), Gaps = 13/275 (4%) Query: 331 ITNPLKNLSLQMKRFSTGSFDAEAAVD--GNDEIAYLSRHFNKMVEKTNELINERYKMKI 388 +T+PL+ L+ MK+ G+ + + + DEIA + + +N+MVE+ N+LIN K++I Sbjct: 324 LTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEI 383 Query: 389 VEKNAVLKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCIS-GRDVV 447 ++ A LKALEA+INPHFLYN L I KA K + ++ EM+ +L+ R ++ G + + Sbjct: 384 NKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFI 443 Query: 448 QAREELKHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHALEKVS 507 Q R E + IERYL LQ R+ ++ + +D +L+ IPKL +Q VEN I H LE S Sbjct: 444 QVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNS 503 Query: 508 STVTIRIEAHITAAHSVISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXXXXXXSIG 567 + + + + D+GPG++E+ L+++ ++ + Sbjct: 504 EESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESE---------NIEEKVGYA 554 Query: 568 LKNLNTRLKLLYGEEAGLVIAGNE-QGTRIDMRLP 601 ++N+N RL+L YG++ L I + +GT I + LP Sbjct: 555 IRNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 142 bits (358), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 88/273 (32%), Positives = 148/273 (54%), Gaps = 13/273 (4%) Query: 331 ITNPLKNLSLQMKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNELINERYKMKIVE 390 I P+ L M S G+FD+ + NDEI+ L + FN+M+ LIN+ Y+++ + Sbjct: 306 IVKPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQK 365 Query: 391 KNAVLKALEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCIS-GRDVVQA 449 ++A L+ L+++INPHFLYN L I KAL+ N ++V+M++ L+ R +S G++ + Sbjct: 366 RSAELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITI 425 Query: 450 REELKHIERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHALEKVSST 509 +E+ H+ YL +QK R+ ++ D + SL + IPKL +Q LVEN I H L+ Sbjct: 426 SDEVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKLQKHK 485 Query: 510 VTIRIEAHITAAHSVISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXXXXXXSIGLK 569 I + I V+D+G G+ ++L+ + +L W GL Sbjct: 486 GIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNL---WESIETNHY--------GLY 534 Query: 570 NLNTRLKLLYGEEAGLVIAGNEQ-GTRIDMRLP 601 N+N RLKL +G++ + I + GT++ +R+P Sbjct: 535 NINERLKLAFGKKYSIEIKSELKIGTQVLLRIP 567 >ref|NP_691698.1| hypothetical protein OB0777 [Oceanobacillus iheyensis HTE831] dbj|BAC12733.1| hypothetical conserved protein [Oceanobacillus iheyensis HTE831] Length = 577 Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 85/265 (32%), Positives = 136/265 (51%), Gaps = 20/265 (7%) Query: 338 LSLQMKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNELINERYKMKIVEKNAVLKA 397 L+ Q K+ TG+ A VD NDEI L FNKMV+ + I+ Y++KI +K + LK Sbjct: 320 LTKQTKQVETGNLTASVHVDSNDEIGKLGYRFNKMVKTIQKHIDTEYRLKIKQKESELKV 379 Query: 398 LEAEINPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCI-SGRDVVQAREELKHI 456 L+ +INPHFLYN L I A N + ++++ L+ R + +G+ +V+ EE+++ Sbjct: 380 LQNQINPHFLYNTLDMIRWNARLENAPETSQLIERLSKIFRMNLNNGKSLVKFEEEVEYS 439 Query: 457 ERYLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHALEKVSSTVTIRIEA 516 + YL LQK R G ++ + + L + K IQ L+EN I+H + + IRI Sbjct: 440 QAYLELQKKRLGEKLDYQLVMEEQLKGYYVMKQMIQPLIENSIQHGFKNLPRQGIIRIHC 499 Query: 517 HITAAHSVISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXXXXXXSIGLKNLNTRLK 576 + +VI V+D+G G E + L + LKNLN R+ Sbjct: 500 YRDENQAVIDVIDNGWGFNEHKKNGELRA-------------------GYALKNLNDRIS 540 Query: 577 LLYGEEAGLVIAGNEQGTRIDMRLP 601 +++G+ GL I +++G + M LP Sbjct: 541 IVFGKLYGLTILDSDEGAFLRMILP 565 >ref|NP_244545.1| two-component sensor histidine kinase [Bacillus halodurans] pir||F84109 two-component sensor histidine kinase BH3678 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07397.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 605 Score = 139 bits (349), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 99/329 (30%), Positives = 158/329 (48%), Gaps = 16/329 (4%) Query: 282 SQKEGWKLVKPIPYKQIYEAATTTRKLSYXXXXXXXXXXXXXXXXXXNRITNPLKNLSLQ 341 S K GW L+ P + + T + ITNP++ L+ Sbjct: 270 SNKTGWSLLIYTPVHSLAQGITGIGTAILVAGGIGLLIFTISTYFLSSLITNPIQRLTHA 329 Query: 342 MKRFSTGSFDAEAAVDGNDEIAYLSRHFNKMVEKTNELINERYKMKIVEKNAVLKALEAE 401 M+ + G+ ++ E+ L+ +N+MVE TN LI Y+ ++ + A LKAL+++ Sbjct: 330 MRFGTLGALKESPSIASTVELNELNDTYNRMVETTNYLIKVVYEQELTQSRAELKALQSQ 389 Query: 402 INPHFLYNALQAISTKALKNNNDDIVEMVDNLALTLRYCIS---GRDVVQAREELKHIER 458 INPHFL+N L+A+ +L+ +++ E+V LA RY IS G D V EE HIER Sbjct: 390 INPHFLFNTLEALYW-SLEEKDEEQAEVVIALAELFRYTISDVKGDDWVALHEEFDHIER 448 Query: 459 YLALQKARFGSRMQVEYDWNDSLLELRIPKLSIQTLVENCIKHALEKVSSTVTIRIEAHI 518 YL + K R+ R+ E + + SL E++IPKL IQ +VEN I H + +++ A+ Sbjct: 449 YLHIMKLRYDHRLAWEIELDPSLREVQIPKLLIQPVVENAIIHGIGNKVDGGKVQVSAYT 508 Query: 519 TAAHSV--ISVLDDGPGITEQRLQQVLSSLQIQWXXXXXXXXXXXXXXSIGLKNLNTRLK 576 + I+V DDG G+ E+ Q++ SL+ + I L N+ RL Sbjct: 509 SVKQGYVNITVRDDGQGMDEKTKQKLEHSLETR-------VGHPEKRSGIALVNIRQRLD 561 Query: 577 LLYGEEAGLVIAGNEQ---GTRIDMRLPR 602 L Y + I + GT + +P+ Sbjct: 562 LCYASDPHTSIELTSRHGVGTTVTFTIPK 590 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.133 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 796,925,140 Number of extensions: 31496733 Number of successful extensions: 95191 Number of sequences better than 1.0e-05: 171 Number of HSP's gapped: 94982 Number of HSP's successfully gapped: 171 Length of query: 614 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 482 Effective length of database: 398,844,510 Effective search space: 192243053820 Effective search space used: 192243053820 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 129 (54.3 bits)