BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0010.p (187 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_658247.1| tetR, Bacterial regulatory proteins, tetR famil... 86 4e-16 ref|NP_980580.1| transcriptional regulator, TetR family [Bacillu... 84 2e-15 ref|NP_470187.1| similar to transcription regulator TetR/AcrR fa... 82 9e-15 ref|NP_465612.1| similar to transcription regulators [Listeria m... 79 6e-14 ref|NP_833926.1| Transcriptional regulator, TetR family [Bacillu... 79 7e-14 >ref|NP_658247.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_846662.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP28148.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 191 Score = 86.3 bits (212), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 51/183 (27%), Positives = 87/183 (47%), Gaps = 1/183 (0%) Query: 4 ALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLDQLYK 63 ALS FA G+EG SLA IAQ VGIKK SI +F KE+L+ + + ++ + Sbjct: 10 ALSHFARYGYEGTSLANIAQEVGIKKPSIYAHFKGKEELYFICLESALQKDLQSFTDDIE 69 Query: 64 EILGTPVEARLREIVYRTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQRSAA 123 + E L +++ + Y R + F+ R+ FP F+E + ++ + + Sbjct: 70 NFSNSSTEELLLQLL-KGYAKRFGESEESMFWLRTSYFPPDAFREQIIEKANAHIENVGK 128 Query: 124 FYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEIFWAG 183 +F++ E+ + L A+ CL DG+ +++ F F RL W++FW G Sbjct: 129 LLFPIFKQANEKSELHNIEVKDALEAFLCLLDGLMVELLFAGLNRFETRLNASWQVFWRG 188 Query: 184 IKQ 186 + Sbjct: 189 LSN 191 >ref|NP_980580.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS43188.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 191 Score = 83.6 bits (205), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 51/183 (27%), Positives = 87/183 (47%), Gaps = 1/183 (0%) Query: 4 ALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLDQLYK 63 ALS FA G+EG SLA IAQ VGIKK SI +F KE+L+ + + ++ + Sbjct: 10 ALSHFARYGYEGTSLANIAQEVGIKKPSIYAHFKGKEELYFICLESALQKDLQSFTGDIE 69 Query: 64 EILGTPVEARLREIVYRTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQRSAA 123 + + E L +++ + Y R + F+ R+ FP F+E + + ++ + Sbjct: 70 KFSNSSTEELLLQLL-KGYAKRFGESEESMFWLRTSYFPPDAFREQIINKANVHIENVGK 128 Query: 124 FYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEIFWAG 183 VF+ E+ + L A+ CL DG+ +++ + F RL W++FW G Sbjct: 129 LLFPVFKRASEQDELHNIEVKDALEAFLCLLDGLMVELLYAGLNRFETRLDASWKVFWRG 188 Query: 184 IKQ 186 + Sbjct: 189 LSN 191 >ref|NP_470187.1| similar to transcription regulator TetR/AcrR family [Listeria innocua] pir||AE1538 transcription regulator TetR/AcrR family homolog lin0845 [imported] - Listeria innocua (strain Clip11262) emb|CAC96077.1| lin0845 [Listeria innocua] Length = 184 Score = 81.6 bits (200), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 11/181 (6%) Query: 2 QAALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLDQL 61 + AL+ FAEKG++G +L+ IA+ VGIK S+ +FP KE LF+ +Q+ + L ++ Sbjct: 8 EVALTLFAEKGYDGTALSEIAKAVGIKTPSLYAHFPSKEALFMEVYQDSIHTELSELSKV 67 Query: 62 Y-KEILGTPVEARLREIVY-RTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQ 119 +E LG E +LR I + T + R P F++R+V +P E L+++ EQ Sbjct: 68 ADEEALGG--EEKLRTIFFVATDFSRS--PDEKKFFQRAVFYPPKSLFEELKEETRTYEQ 123 Query: 120 RSAAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEI 179 + R E + + R + +Y L DG++++ Y++ EF R K WE+ Sbjct: 124 LTNDILRKTLEPALPEDALTR-----WMHVFYALLDGLSVEHGIYDETEFELRRKSAWEV 178 Query: 180 F 180 Sbjct: 179 L 179 >ref|NP_465612.1| similar to transcription regulators [Listeria monocytogenes EGD-e] pir||AH1335 transcription regulators homolog lmo2088 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAD00166.1| lmo2088 [Listeria monocytogenes] Length = 196 Score = 79.0 bits (193), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 56/189 (29%), Positives = 95/189 (50%), Gaps = 12/189 (6%) Query: 2 QAALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDLFIAAFQEMARHYIEFLD-Q 60 QAAL+ FA GFEG SLA IA +VG+KKQSI ++F K+DLF++ ++ I++ + Sbjct: 8 QAALTLFANNGFEGTSLADIAGVVGLKKQSIYSHFKDKDDLFLSIMKDAKSTEIDYYRAK 67 Query: 61 LYKEILGTPVEARLREIVYRTYYYRVE--YPVLTA--FYKRSVQFPAPFFQEMLEQQISM 116 L L P ++V + + V+ Y A F+ R +P E+++ I+ Sbjct: 68 LRDSDLSRP------DLVLSSLLFGVKELYDTDEAYQFWLRYGFYPPKHLYEVVQADITE 121 Query: 117 MEQRSAAFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQ-EEFGRRLKD 175 + + +F M I Q E++ AY + D + + + + N E +++ Sbjct: 122 NVLQMEHEFTDLFSNWMEQKLIPMQDVETMKEAYMGILDAVIVDIVYVNDPERTEKKITA 181 Query: 176 IWEIFWAGI 184 +W+IFW GI Sbjct: 182 LWQIFWRGI 190 >ref|NP_833926.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP11127.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 193 Score = 78.6 bits (192), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 54/184 (29%), Positives = 83/184 (45%), Gaps = 3/184 (1%) Query: 4 ALSEFAEKGFEGASLAGIAQLVGIKKQSIATYFPKKEDL-FIAAFQEMARHYIEFLDQLY 62 ALS FA G+EG SLA IAQ VGIKK SI +F KE+L FI + + F + Sbjct: 12 ALSHFARYGYEGTSLANIAQEVGIKKPSIYAHFKGKEELYFICLESALQKDLQSFTGDI- 70 Query: 63 KEILGTPVEARLREIVYRTYYYRVEYPVLTAFYKRSVQFPAPFFQEMLEQQISMMEQRSA 122 E L + + Y R + F+ R+ FP F+E + + ++ + Sbjct: 71 -ESFSNSSTEELLLKLLKGYAKRFGESEESMFWLRTSYFPPDAFREQIINKANVHIENVG 129 Query: 123 AFYRAVFEEGMNSGEIRRQHTESLLSAYYCLQDGIAMQMFFYNQEEFGRRLKDIWEIFWA 182 VF+ E+ + L A+ CL DG+ +++ + F RL W++FW Sbjct: 130 KLLFPVFKRASEQDELHNIEVKDALEAFLCLLDGLMVELLYAGLNRFETRLDASWKVFWR 189 Query: 183 GIKQ 186 G+ Sbjct: 190 GLSN 193 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.325 0.138 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 252,340,499 Number of extensions: 9056295 Number of successful extensions: 32292 Number of sequences better than 1.0e-05: 21 Number of HSP's gapped: 32321 Number of HSP's successfully gapped: 21 Length of query: 187 Length of database: 757,237,578 Length adjustment: 118 Effective length of query: 69 Effective length of database: 436,855,896 Effective search space: 30143056824 Effective search space used: 30143056824 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 122 (51.6 bits)