BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0340.0016.p (353 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_981302.1| sensor histidine kinase [Bacillus cereus ATCC 1... 480 e-134 ref|NP_658883.1| HATPase_c, Histidine kinase-, DNA gyrase B-, ph... 479 e-134 ref|NP_242675.1| two-component sensor histidine kinase [Bacillus... 467 e-130 ref|NP_834548.1| Sensor protein vanS [Bacillus cereus ATCC 14579... 452 e-126 gb|AAQ04069.1| two-component sensor protein kinase [Paenibacillu... 413 e-114 >ref|NP_981302.1| sensor histidine kinase [Bacillus cereus ATCC 10987] gb|AAS43910.1| sensor histidine kinase [Bacillus cereus ATCC 10987] Length = 368 Score = 480 bits (1235), Expect = e-134, Method: Compositional matrix adjust. Identities = 230/350 (65%), Positives = 289/350 (82%) Query: 1 MLMLFGLSMLISGLLTYLVYKGLQFYYHEKVLAEDDIARLRAIIYRIGDVNFFLILFVPL 60 M+MLF LSM+ + +TY++Y+GL+ YY V ED +A++R+II +IGDVNFFLI+F+PL Sbjct: 12 MVMLFALSMICAAGVTYIIYEGLRIYYKLVVRFEDPLAQVRSIIRQIGDVNFFLIIFIPL 71 Query: 61 AIFFFFLLTKRYAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAEDINRASEQLQKA 120 +I FFF LT+ Y YFD IS+GIH+LANG+F++ V ++S+DEF IA +IN ASE+L++A Sbjct: 72 SIMFFFFLTRPYLKYFDEISNGIHHLANGDFTNEVRVSSNDEFGYIASEINVASEKLREA 131 Query: 121 VERGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQR 180 VERGDFAESSKDQLV+NLAHD+RTPLTSVLGYLD IL +LT EQ+KH++ IAYTKSQR Sbjct: 132 VERGDFAESSKDQLVVNLAHDLRTPLTSVLGYLDLILKDENLTKEQIKHFSTIAYTKSQR 191 Query: 181 LEKLIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKLTSRLQITPQMVI 240 LE LI+ELFEITR+NYGML + K PID+SELL QL+EELYPL EK+ L +RL + + I Sbjct: 192 LESLIDELFEITRMNYGMLKLDKKPIDISELLIQLDEELYPLLEKHHLEARLNVDSHLPI 251 Query: 241 PADGELLARVFENLLTNAARYGRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLFD 300 DG+LLARVFENLLTNA RYG DGQFVD++ + G VVQ+INYG+ IP E+LP++FD Sbjct: 252 NGDGKLLARVFENLLTNAVRYGYDGQFVDLNGYIDNGEVVVQVINYGDSIPEEDLPYVFD 311 Query: 301 MFYTGDRARTSDANSTGLGLFIAKNIVEQHGGTISAESSVTRTLFEVRLP 350 MFYTGD++RT + TGLGLFIAKNI+EQH GTISAES+V RT+FEVRLP Sbjct: 312 MFYTGDKSRTENRGGTGLGLFIAKNIIEQHNGTISAESNVVRTMFEVRLP 361 >ref|NP_658883.1| HATPase_c, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase [Bacillus anthracis A2012] ref|NP_847291.1| sensor histidine kinase [Bacillus anthracis str. Ames] gb|AAP28777.1| sensor histidine kinase [Bacillus anthracis str. Ames] Length = 368 Score = 479 bits (1233), Expect = e-134, Method: Compositional matrix adjust. Identities = 229/350 (65%), Positives = 285/350 (81%) Query: 1 MLMLFGLSMLISGLLTYLVYKGLQFYYHEKVLAEDDIARLRAIIYRIGDVNFFLILFVPL 60 M+ LF LSM+++ +TY++YKGLQ YY V E+ +A+ R+I+ GD+NFFLI F+PL Sbjct: 12 MIALFALSMVLAATVTYIIYKGLQLYYKTMVRYEEPLAQFRSIVREFGDINFFLIFFIPL 71 Query: 61 AIFFFFLLTKRYAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAEDINRASEQLQKA 120 +I FFF LTK Y YF IS+GIH+LANG F++RV+++S+DEF IA +IN ASE+L++A Sbjct: 72 SIIFFFFLTKPYLKYFSEISNGIHHLANGNFTNRVQVSSNDEFGDIAREINVASEKLKEA 131 Query: 121 VERGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQR 180 VERGDFAESSKDQLV+NLAHD+RTPLTSVLGYLD IL +LT EQ+KH++ IAYTKSQR Sbjct: 132 VERGDFAESSKDQLVVNLAHDLRTPLTSVLGYLDLILKDENLTKEQIKHFSTIAYTKSQR 191 Query: 181 LEKLIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKLTSRLQITPQMVI 240 LE LI+ELFEITR+NYGML + K PID+SELL QL+EELYPL EK+ L +RL + P + I Sbjct: 192 LESLIDELFEITRMNYGMLQLNKKPIDISELLIQLDEELYPLLEKHHLEARLNVDPHLPI 251 Query: 241 PADGELLARVFENLLTNAARYGRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLFD 300 DG+LLARVFENLLTNA RYG DGQFVD++ + VVQ++NYG+ IP E+LP+LFD Sbjct: 252 NGDGKLLARVFENLLTNAVRYGYDGQFVDLNGYIDNEEVVVQVMNYGDSIPEEDLPYLFD 311 Query: 301 MFYTGDRARTSDANSTGLGLFIAKNIVEQHGGTISAESSVTRTLFEVRLP 350 MFYTGD++RT + TGLGLFIAKNIVEQH GTISAES+V RT+FEVRLP Sbjct: 312 MFYTGDKSRTENRGGTGLGLFIAKNIVEQHNGTISAESNVVRTIFEVRLP 361 >ref|NP_242675.1| two-component sensor histidine kinase [Bacillus halodurans] pir||A83876 two-component sensor histidine kinase BH1809 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05528.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 351 Score = 467 bits (1202), Expect = e-130, Method: Compositional matrix adjust. Identities = 230/347 (66%), Positives = 280/347 (80%), Gaps = 1/347 (0%) Query: 4 LFGLSMLISGLLTYLVYKGLQFYYHEKVLAEDDIARLRAIIYRIGDVNFFLILFVPLAIF 63 +FGLS+L S +TYLV+KGLQ YY+ V ED + LR I RIGDVNFFL+LF+PL+I Sbjct: 1 MFGLSILFSSTITYLVFKGLQLYYYTMVDYEDPLVELRLFIGRIGDVNFFLLLFIPLSIL 60 Query: 64 FFFLLTKRYAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAEDINRASEQLQKAVER 123 FFF LTK Y+ YF+ IS GIH LA G+F+ V+I + DEF+ IA DIN+AS+ LQ+A+ R Sbjct: 61 FFFWLTKPYSTYFNEISKGIHYLARGDFTHIVQIQAKDEFKNIAHDINQASKNLQQAIAR 120 Query: 124 GDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQRLEK 183 GDF+ESSKDQLV+NLAHD+RTPLTSV+GYLD IL DLT EQV+H+ MIA+TKSQRLE+ Sbjct: 121 GDFSESSKDQLVVNLAHDLRTPLTSVIGYLDLILKEKDLTEEQVRHFLMIAFTKSQRLER 180 Query: 184 LIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKLTSRLQITPQMVIPAD 243 LI+ELFEITR+NYGML V K IDLS+LL QL EELYPLFEKN L +R + + I D Sbjct: 181 LIDELFEITRMNYGMLPVNKKNIDLSDLLLQLKEELYPLFEKNHLIARTNMKTPLPILGD 240 Query: 244 GELLARVFENLLTNAARYGRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLFDMFY 303 GELLARVFENLLTNA RYG DG+F+DI+ + V+QI+NYG+ IP +ELP +FDMFY Sbjct: 241 GELLARVFENLLTNANRYGYDGKFIDINGFIDSEEVVIQIVNYGDQIPPDELPHVFDMFY 300 Query: 304 TGDRARTSDANSTGLGLFIAKNIVEQHGGTISAESSVTRTLFEVRLP 350 TGD+ART D +STGLGLFIAKNIVEQHGGT++A+SS+ RT+FEVRLP Sbjct: 301 TGDKARTKD-DSTGLGLFIAKNIVEQHGGTVTADSSLIRTVFEVRLP 346 >ref|NP_834548.1| Sensor protein vanS [Bacillus cereus ATCC 14579] gb|AAP11749.1| Sensor protein vanS [Bacillus cereus ATCC 14579] Length = 368 Score = 452 bits (1162), Expect = e-126, Method: Compositional matrix adjust. Identities = 229/350 (65%), Positives = 286/350 (81%) Query: 1 MLMLFGLSMLISGLLTYLVYKGLQFYYHEKVLAEDDIARLRAIIYRIGDVNFFLILFVPL 60 M+ LF LSM+++ +TY++YKGLQ YY V E+ +A+ R+++ GD+NFFLI F+PL Sbjct: 12 MIALFALSMVLAATVTYIIYKGLQLYYKTMVRYEEPLAQFRSMVREFGDINFFLIFFIPL 71 Query: 61 AIFFFFLLTKRYAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAEDINRASEQLQKA 120 +I FFF LTK Y YFD IS+GIH+LANG F+++V+++S+DEF IA +IN ASE+L++A Sbjct: 72 SIIFFFFLTKPYLKYFDEISNGIHHLANGNFTNKVQVSSNDEFGNIAREINVASEKLKEA 131 Query: 121 VERGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQR 180 VERGDFAE+SKDQLV+NLAHD+RTPLTSVLGYLD IL +LT EQ+KH++ IAYTKSQR Sbjct: 132 VERGDFAENSKDQLVVNLAHDLRTPLTSVLGYLDLILKDENLTKEQIKHFSTIAYTKSQR 191 Query: 181 LEKLIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKLTSRLQITPQMVI 240 LE LI+ELFEITR+NYGML + K PID+SELL QL EELYPL EK+ L +RL + P + + Sbjct: 192 LESLIDELFEITRMNYGMLNLDKKPIDISELLIQLEEELYPLLEKHHLEARLNVAPHLPM 251 Query: 241 PADGELLARVFENLLTNAARYGRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLFD 300 DG+LLARVFENLLTNA RYG DGQFVD++ + G VVQI+NYG+ IP E+LP+LFD Sbjct: 252 HGDGKLLARVFENLLTNAVRYGYDGQFVDMNGYVDNGEVVVQIMNYGDSIPEEDLPYLFD 311 Query: 301 MFYTGDRARTSDANSTGLGLFIAKNIVEQHGGTISAESSVTRTLFEVRLP 350 MFYTGD+ART + TGLGLFIAKNIVEQH GTISAES+V RT+FEVRLP Sbjct: 312 MFYTGDKARTENRGGTGLGLFIAKNIVEQHNGTISAESNVVRTIFEVRLP 361 >gb|AAQ04069.1| two-component sensor protein kinase [Paenibacillus popilliae] Length = 346 Score = 413 bits (1062), Expect = e-114, Method: Compositional matrix adjust. Identities = 219/343 (63%), Positives = 268/343 (78%) Query: 9 MLISGLLTYLVYKGLQFYYHEKVLAEDDIARLRAIIYRIGDVNFFLILFVPLAIFFFFLL 68 ML+S +TYL++K LQ YY+ V D +A R II IGD N FL+LF+ L+I FFFLL Sbjct: 1 MLLSSAITYLLFKVLQLYYYTSVDYGDTLAYFRKIIQNIGDFNVFLLLFILLSILFFFLL 60 Query: 69 TKRYAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAEDINRASEQLQKAVERGDFAE 128 TK Y+AYF+ IS GIH LA G+F RV+I S+DEF IA+ IN ASE+L++A+ERGDF+E Sbjct: 61 TKPYSAYFNEISKGIHYLAQGDFKHRVQILSNDEFSDIAQSINLASEKLEQAIERGDFSE 120 Query: 129 SSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQRLEKLIEEL 188 SSK+QLV+NLAHD+RTPLTSVLGYLD IL +LT Q++HY IA+TKSQRLE+LI+EL Sbjct: 121 SSKEQLVVNLAHDLRTPLTSVLGYLDLILKDDNLTENQIRHYLTIAFTKSQRLERLIDEL 180 Query: 189 FEITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKLTSRLQITPQMVIPADGELLA 248 FEITR+NYGML + K IDLSELL QL EELYP+FEKN L +R+ IT + I DGELLA Sbjct: 181 FEITRMNYGMLPIKKKQIDLSELLIQLKEELYPVFEKNDLIARMNITSPLSIMGDGELLA 240 Query: 249 RVFENLLTNAARYGRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLFDMFYTGDRA 308 RVFENLL NA RYG +GQ+VDI + V+Q+INYG+ IP +ELP +FDM +TGD+A Sbjct: 241 RVFENLLINANRYGYEGQYVDIIGFIDSEEVVIQVINYGDAIPPDELPHIFDMLFTGDKA 300 Query: 309 RTSDANSTGLGLFIAKNIVEQHGGTISAESSVTRTLFEVRLPI 351 RT NSTGLGLFIA NIVEQH GTI+AES + RT+FEVRLP+ Sbjct: 301 RTHQENSTGLGLFIADNIVEQHNGTITAESDLIRTIFEVRLPM 343 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.324 0.140 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 473,759,364 Number of extensions: 19034899 Number of successful extensions: 88314 Number of sequences better than 1.0e-05: 3956 Number of HSP's gapped: 84473 Number of HSP's successfully gapped: 3968 Length of query: 353 Length of database: 757,237,578 Length adjustment: 127 Effective length of query: 226 Effective length of database: 412,420,005 Effective search space: 93206921130 Effective search space used: 93206921130 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 126 (53.1 bits)