BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0340.0012.p (91 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_655326.1| TP_methylase, Tetrapyrrole (Corrin/Porphyrin) M... 95 4e-19 ref|NP_977870.1| uroporphyrin-III C-methyltransferase [Bacillus ... 95 5e-19 ref|NP_831206.1| Uroporphyrin-III C-methyltransferase [Bacillus ... 94 7e-19 emb|CAD48921.1| uroporphyrinogen III methyltransferase [Bacillus... 88 6e-17 ref|ZP_00128309.1| COG1648: Siroheme synthase (precorrin-2 oxida... 83 2e-15 >ref|NP_655326.1| TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases [Bacillus anthracis A2012] ref|NP_843901.1| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Ames] gb|AAP25387.1| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Ames] Length = 258 Score = 95.1 bits (235), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 47/88 (53%), Positives = 61/88 (69%) Query: 1 VDTLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMK 60 V+TL +YMGVS L I EQL+KHGKD +TPAA+IE GTT +R V GTLG I +A + Sbjct: 163 VETLAVYMGVSNLPYICEQLMKHGKDKSTPAAIIERGTTSMQRTVVGTLGTIVDVAKKEQ 222 Query: 61 ISNPAIIIIGESVTVRDQLLSLEKAVRS 88 I NP++I+IGE V R+++ EK S Sbjct: 223 IQNPSMIVIGEVVRFREKIHWFEKQTES 250 >ref|NP_977870.1| uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 10987] gb|AAS40478.1| uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 10987] Length = 258 Score = 94.7 bits (234), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 47/88 (53%), Positives = 61/88 (69%) Query: 1 VDTLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMK 60 V+TL +YMGVS L I EQL+KHGKD +TPAA+IE GTT +R V GTLG I +A + Sbjct: 163 VETLAVYMGVSNLPYICEQLIKHGKDKSTPAAIIERGTTSMQRTVVGTLGTIVDVAKKEQ 222 Query: 61 ISNPAIIIIGESVTVRDQLLSLEKAVRS 88 I NP++I+IGE V R ++ EK + S Sbjct: 223 IQNPSMIVIGEVVRFRGKIHWFEKQIES 250 >ref|NP_831206.1| Uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 14579] gb|AAP08407.1| Uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 14579] Length = 259 Score = 94.4 bits (233), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 46/84 (54%), Positives = 60/84 (71%) Query: 1 VDTLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMK 60 V+TL +YMGVS L I EQL+KHGKD +TPAA+IE GTT +R V GTLG I +A + Sbjct: 164 VETLAVYMGVSNLPYICEQLMKHGKDKSTPAAIIEQGTTSMQRTVVGTLGTIVDVAKKEQ 223 Query: 61 ISNPAIIIIGESVTVRDQLLSLEK 84 I NP++I+IGE V R+++ EK Sbjct: 224 IQNPSMIVIGEVVRFREKIHWFEK 247 >emb|CAD48921.1| uroporphyrinogen III methyltransferase [Bacillus megaterium] Length = 259 Score = 88.2 bits (217), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 45/84 (53%), Positives = 54/84 (64%) Query: 1 VDTLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMK 60 VDTL IYMGV L I +QL+KHGK ATP ALI GT +R VTGTLG I + + Sbjct: 163 VDTLAIYMGVRNLPYICQQLMKHGKTSATPIALIHWGTCADQRTVTGTLGTIVDIVKEEQ 222 Query: 61 ISNPAIIIIGESVTVRDQLLSLEK 84 I NP++II+GE V D+L EK Sbjct: 223 IENPSMIIVGEVVNFHDRLNWFEK 246 >ref|ZP_00128309.1| COG1648: Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Pseudomonas syringae pv. syringae B728a] Length = 464 Score = 83.2 bits (204), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 40/83 (48%), Positives = 55/83 (66%) Query: 3 TLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMKIS 62 TL+ YMG+ L I EQL++HG+ TPAAL+E GTTV +R TGTL N+ +L A + Sbjct: 378 TLVFYMGLIGLPVICEQLIRHGRSADTPAALVEQGTTVNQRVFTGTLANLPQLVAEHDVH 437 Query: 63 NPAIIIIGESVTVRDQLLSLEKA 85 P ++IIGE V +R++L E A Sbjct: 438 APTLVIIGEVVKLREKLAWFEGA 460 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.133 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 112,756,245 Number of extensions: 3572093 Number of successful extensions: 12140 Number of sequences better than 1.0e-05: 200 Number of HSP's gapped: 12117 Number of HSP's successfully gapped: 200 Length of query: 91 Length of database: 757,237,578 Length adjustment: 59 Effective length of query: 32 Effective length of database: 597,046,737 Effective search space: 19105495584 Effective search space used: 19105495584 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 120 (50.8 bits)