BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0317.0004.p (218 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|Q08291|ISPA_BACST Geranyltranstransferase (Farnesyl-diphospha... 193 2e-48 ref|NP_464888.1| similar to geranyltranstransferase [Listeria mo... 191 7e-48 gb|EAI73873.1| unknown [environmental sequence] 187 2e-46 ref|ZP_00097861.1| COG0142: Geranylgeranyl pyrophosphate synthas... 186 4e-46 ref|NP_372045.1| geranyltranstransferase homolog [Staphylococcu... 184 9e-46 >sp|Q08291|ISPA_BACST Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase) pir||JX0257 geranyltranstransferase (EC 2.5.1.10) - Bacillus stearothermophilus dbj|BAA02551.1| farnesyl diphosphate synthase [Geobacillus stearothermophilus] Length = 297 Score = 193 bits (491), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 100/195 (51%), Positives = 130/195 (66%), Gaps = 3/195 (1%) Query: 1 MVHTYSLIHDDLPAMDNDDYRRGKLTNHKVYGEATAILAGDALLTHAFYSVVQASRKHGV 60 M+HTYSLIHDDLP+MDNDD RRGK TNHKV+GEA AILAGD LLT+AF + + + + Sbjct: 77 MIHTYSLIHDDLPSMDNDDLRRGKPTNHKVFGEAMAILAGDGLLTYAFQLITEIDDER-I 135 Query: 61 PAEHALSVVEDLAEMAGPRGMVGGQIADMEGEQGLTSLEQLQX--XXXXGDLIVFSLTAG 118 P L ++E LA+ AGP GMV GQ ADMEGE +L +L+ G ++ +S+ AG Sbjct: 136 PPSVRLRLIERLAKAAGPEGMVAGQAADMEGEGKTLTLSELEYIHRHKTGKMLQYSVHAG 195 Query: 119 GRIAGADSRQLEALRDFGTHIGLAFQIQDDILDLVGDEGKLGKKTGSDLKQQKVTYPYFI 178 I GAD+RQ L +F H+GLAFQI+DDILD+ G E K+GK GSD K TYP + Sbjct: 196 ALIGGADARQTRELDEFAAHLGLAFQIRDDILDIEGAEEKIGKPVGSDQSNNKATYPALL 255 Query: 179 GLDASRDEVKRLTEA 193 L +++++ EA Sbjct: 256 SLAGAKEKLAFHIEA 270 >ref|NP_464888.1| similar to geranyltranstransferase [Listeria monocytogenes EGD-e] pir||AC1245 geranyltranstransferase homolog lmo1363 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99441.1| lmo1363 [Listeria monocytogenes] Length = 293 Score = 191 bits (486), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 95/186 (51%), Positives = 130/186 (69%), Gaps = 5/186 (2%) Query: 1 MVHTYSLIHDDLPAMDNDDYRRGKLTNHKVYGEATAILAGDALLTHAFYSVVQASRKHGV 60 M+HTYSLIHDDLPAMDNDDYRRGK TNHKV+G+ATAILAGDALLT AF + + + Sbjct: 75 MIHTYSLIHDDLPAMDNDDYRRGKWTNHKVFGDATAILAGDALLTLAFSILAE---DDNL 131 Query: 61 PAEHALSVVEDLAEMAGPRGMVGGQIADMEGEQGLTSLEQLQX--XXXXGDLIVFSLTAG 118 E ++++ ++ +G GMVGGQ+AD+E E +LE+L G+L+++++T+ Sbjct: 132 SFETRIALINQISFSSGAEGMVGGQLADLEAENKQVTLEELSSIHARKTGELLIYAVTSA 191 Query: 119 GRIAGADSRQLEALRDFGTHIGLAFQIQDDILDLVGDEGKLGKKTGSDLKQQKVTYPYFI 178 +IA AD Q + LR F +IG+ FQI DDILD++GDE K+GKKTG+D K TYP + Sbjct: 192 AKIAEADPEQTKRLRIFAENIGIGFQISDDILDVIGDETKMGKKTGADAFLNKSTYPGLL 251 Query: 179 GLDASR 184 LD ++ Sbjct: 252 TLDGAK 257 >gb|EAI73873.1| unknown [environmental sequence] Length = 296 Score = 187 bits (474), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 98/194 (50%), Positives = 125/194 (64%), Gaps = 2/194 (1%) Query: 1 MVHTYSLIHDDLPAMDNDDYRRGKLTNHKVYGEATAILAGDALLTHAFYSVVQASRKHGV 60 ++HTY+LIHDDLPA+DNDD RRGK TNHKV+GEA AILAGDALLT AF + +A+ V Sbjct: 75 LIHTYTLIHDDLPALDNDDLRRGKPTNHKVFGEAIAILAGDALLTQAFIIMTRAAGMVTV 134 Query: 61 PAEHALSVVEDLAEMAGPRGMVGGQIADMEGEQGLTSLEQLQX--XXXXGDLIVFSLTAG 118 P + L ++A G GM+GGQ+ D+E E + E L+ G LI + G Sbjct: 135 PPQCILKATHEMAGALGSTGMIGGQVVDLESEGKRINSETLEYIHIYKTGFLIRACIRCG 194 Query: 119 GRIAGADSRQLEALRDFGTHIGLAFQIQDDILDLVGDEGKLGKKTGSDLKQQKVTYPYFI 178 G ++ A QL +L FG HIGLAFQI DDILD+ GD+ KLGK GSDL + K TYP Sbjct: 195 GVLSQASKGQLSSLSSFGAHIGLAFQIIDDILDITGDQEKLGKDIGSDLTKNKATYPALY 254 Query: 179 GLDASRDEVKRLTE 192 GL+ S+ + + L E Sbjct: 255 GLEESKRKAEELVE 268 >ref|ZP_00097861.1| COG0142: Geranylgeranyl pyrophosphate synthase [Desulfitobacterium hafniense] Length = 319 Score = 186 bits (471), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 99/191 (51%), Positives = 127/191 (66%), Gaps = 6/191 (3%) Query: 1 MVHTYSLIHDDLPAMDNDDYRRGKLTNHKVYGEATAILAGDALLTHAFYSVVQASRKHGV 60 ++HTYSLIHDDLPAMDNDDYRRG+L NHKV+GE AILAGDALLT+AF + Q GV Sbjct: 100 LIHTYSLIHDDLPAMDNDDYRRGRLANHKVFGEGQAILAGDALLTYAFELLAQP--MSGV 157 Query: 61 PAEHALSVVEDLAEMAGPRGMVGGQIADMEGEQ---GLTSLEQLQXXXXXGDLIVFSLTA 117 ++ L V ++A+ AGP GMVGGQ+ D+E E+ L LEQ+ G ++V + Sbjct: 158 DSQRQLRAVREVAQAAGPEGMVGGQMLDLEAEEKQLNLAELEQVH-RLKTGAILVVAARL 216 Query: 118 GGRIAGADSRQLEALRDFGTHIGLAFQIQDDILDLVGDEGKLGKKTGSDLKQQKVTYPYF 177 G +AG ++EAL + IGLAFQI+DDILDL D LGK SDL+Q K TYP Sbjct: 217 GAILAGGTEEKIEALTSYAQAIGLAFQIKDDILDLESDSETLGKPVHSDLRQHKSTYPSL 276 Query: 178 IGLDASRDEVK 188 +GL ++ E+K Sbjct: 277 MGLAGAKLELK 287 >ref|NP_372045.1| geranyltranstransferase homolog [Staphylococcus aureus subsp. aureus Mu50] ref|NP_374635.1| geranyltranstransferase homolog [Staphylococcus aureus subsp. aureus N315] pir||A89932 hypothetical protein ispA [imported] - Staphylococcus aureus (strain N315) dbj|BAB42614.1| ispA [Staphylococcus aureus subsp. aureus N315] dbj|BAB57683.1| geranyltranstransferase homolog [Staphylococcus aureus subsp. aureus Mu50] Length = 293 Score = 184 bits (468), Expect = 9e-46, Method: Compositional matrix adjust. Identities = 101/212 (47%), Positives = 129/212 (60%), Gaps = 5/212 (2%) Query: 1 MVHTYSLIHDDLPAMDNDDYRRGKLTNHKVYGEATAILAGDALLTHAFYSVVQASRKHGV 60 M+HTYSLIHDDLPAMDNDDYRRGKLTNHKVYGE TAILAGDALLT AF + R + Sbjct: 73 MIHTYSLIHDDLPAMDNDDYRRGKLTNHKVYGEWTAILAGDALLTKAFELISSDDR---L 129 Query: 61 PAEHALSVVEDLAEMAGPRGMVGGQIADMEGEQGLTSLEQLQX--XXXXGDLIVFSLTAG 118 E + V++ L+ +G GMVGGQ+ DM+ E LE L+ G L+ F++ + Sbjct: 130 TDEVKIKVLQRLSIASGHVGMVGGQMLDMQSEGQPIDLETLEMIHKTKTGALLTFAVMSA 189 Query: 119 GRIAGADSRQLEALRDFGTHIGLAFQIQDDILDLVGDEGKLGKKTGSDLKQQKVTYPYFI 178 IA D E L + H+G+ FQI+DD+LD GDE KLGKK GSDL+ K TY + Sbjct: 190 ADIANVDDATKEHLESYSYHLGMMFQIKDDLLDCYGDEAKLGKKVGSDLENNKSTYVSLL 249 Query: 179 GLDASRDEVKRLTEAXXXAALSLKAVFRTIHV 210 G D + D++ +A + F T H+ Sbjct: 250 GKDGAEDKLTYHRDAAVDELTQIDEQFNTKHL 281 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 298,562,045 Number of extensions: 11270079 Number of successful extensions: 26180 Number of sequences better than 1.0e-05: 1260 Number of HSP's gapped: 24714 Number of HSP's successfully gapped: 1260 Length of query: 218 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 97 Effective length of database: 428,710,599 Effective search space: 41584928103 Effective search space used: 41584928103 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 123 (52.0 bits)