BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0311.0015.p (220 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_268527.1| butyrate-acetoacetate CoA-transferase, beta sub... 293 2e-78 ref|NP_663914.1| butyrate-acetoacetate CoA-transferase, beta sub... 290 2e-77 ref|NP_622379.1| Acyl-CoA:acetate CoA transferase beta subunit [... 280 2e-74 ref|NP_269686.1| putative Acetyl-CoA:acetoacetyl-CoA transferase... 276 3e-73 ref|NP_607697.1| putative Acetyl-CoA:acetoacetyl-CoA transferase... 274 1e-72 >ref|NP_268527.1| butyrate-acetoacetate CoA-transferase, beta subunit [Streptococcus pyogenes] ref|NP_606449.1| butyrate-acetoacetate CoA-transferase, beta subunit [Streptococcus pyogenes MGAS8232] gb|AAK33248.1| butyrate-acetoacetate CoA-transferase, beta subunit [Streptococcus pyogenes M1 GAS] gb|AAL96948.1| butyrate-acetoacetate CoA-transferase, beta subunit [Streptococcus pyogenes MGAS8232] Length = 215 Score = 293 bits (750), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 149/214 (69%), Positives = 173/214 (80%), Gaps = 2/214 (0%) Query: 1 VKMDKAELQNMIAKRVAQELKDGELVNLGIGLPTKVANFVSEEVHVTFHSENGFVGLGPA 60 V + K E+QN IAKRVA+EL+DG LVNLGIGLPTKVANFV EE+ V F SENGF+GLGP Sbjct: 3 VALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPEEMTVYFQSENGFIGLGPK 62 Query: 61 QGEEITDPTIVNAGGQYVTINPNGCFFDSATSFGIIRGGHVDLTVLGALQVDEKGNIANY 120 + + TIVNAGGQ VT+ P FF+SA SFGIIRGGHVDLTVLGAL++ E G+IANY Sbjct: 63 SDD--PNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVDLTVLGALEIAENGDIANY 120 Query: 121 MIPGKMVPGMGGAMDLLTGAKKVIVAMEHTSQGKAKILKECTLPLTAKNAVDLIITEMAV 180 +IPGKMVPGMGGAMDLL GAKKVIVAMEHT++GK K+LKECTLPLTAK VDLIITEM V Sbjct: 121 LIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKECTLPLTAKGVVDLIITEMGV 180 Query: 181 IEVTPEGFLLQEINSAYTLEEVLAATEAKLLISE 214 +VTP+G + EI+ +T +EV AAT L I+E Sbjct: 181 FKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAE 214 >ref|NP_663914.1| butyrate-acetoacetate CoA-transferase, beta subunit [Streptococcus pyogenes MGAS315] ref|NP_801374.1| putative butyrate-acetoacetate CoA-transferase beta subunit [Streptococcus pyogenes SSI-1] gb|AAM78717.1| butyrate-acetoacetate CoA-transferase, beta subunit [Streptococcus pyogenes MGAS315] dbj|BAC63207.1| putative butyrate-acetoacetate CoA-transferase beta subunit [Streptococcus pyogenes SSI-1] Length = 215 Score = 290 bits (742), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 148/214 (69%), Positives = 172/214 (80%), Gaps = 2/214 (0%) Query: 1 VKMDKAELQNMIAKRVAQELKDGELVNLGIGLPTKVANFVSEEVHVTFHSENGFVGLGPA 60 V + K E+QN IAKRVA+EL+DG LVNLGIGLPTKVANFV EE+ V F SENGF+GLG Sbjct: 3 VALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPEEMTVYFQSENGFIGLGSK 62 Query: 61 QGEEITDPTIVNAGGQYVTINPNGCFFDSATSFGIIRGGHVDLTVLGALQVDEKGNIANY 120 + + TIVNAGGQ VT+ P FF+SA SFGIIRGGHVDLTVLGAL++ E G+IANY Sbjct: 63 SDD--PNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVDLTVLGALEIAENGDIANY 120 Query: 121 MIPGKMVPGMGGAMDLLTGAKKVIVAMEHTSQGKAKILKECTLPLTAKNAVDLIITEMAV 180 +IPGKMVPGMGGAMDLL GAKKVIVAMEHT++GK K+LKECTLPLTAK VDLIITEM V Sbjct: 121 LIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKECTLPLTAKGVVDLIITEMGV 180 Query: 181 IEVTPEGFLLQEINSAYTLEEVLAATEAKLLISE 214 +VTP+G + EI+ +T +EV AAT L I+E Sbjct: 181 FKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAE 214 >ref|NP_622379.1| Acyl-CoA:acetate CoA transferase beta subunit [Thermoanaerobacter tengcongensis] gb|AAM23983.1| Acyl-CoA:acetate CoA transferase beta subunit [Thermoanaerobacter tengcongensis] Length = 221 Score = 280 bits (715), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 137/214 (64%), Positives = 171/214 (79%) Query: 4 DKAELQNMIAKRVAQELKDGELVNLGIGLPTKVANFVSEEVHVTFHSENGFVGLGPAQGE 63 D+ + +IAKR+A+ELK GELVNLGIGLPT VAN++ E VHV F SENG G+GP Sbjct: 4 DQELAKQIIAKRIAKELKHGELVNLGIGLPTLVANYIPEGVHVIFQSENGITGMGPMPEP 63 Query: 64 EITDPTIVNAGGQYVTINPNGCFFDSATSFGIIRGGHVDLTVLGALQVDEKGNIANYMIP 123 D I+NAGGQYVT+ P FFDSA SF +IRGGHVD+TVLGAL+VDE+GN+AN++IP Sbjct: 64 GKEDVNIINAGGQYVTVMPGAAFFDSAFSFALIRGGHVDVTVLGALEVDEEGNLANWIIP 123 Query: 124 GKMVPGMGGAMDLLTGAKKVIVAMEHTSQGKAKILKECTLPLTAKNAVDLIITEMAVIEV 183 GK+VPGMGGAMDL TGAK+VIVAM+HT++G+ KILK+C LPLTAK V LI+TE+AVIEV Sbjct: 124 GKLVPGMGGAMDLATGAKRVIVAMQHTAKGQPKILKKCRLPLTAKGKVSLIVTELAVIEV 183 Query: 184 TPEGFLLQEINSAYTLEEVLAATEAKLLISEKLK 217 T EG LL+EI+ ++EEV + TEA L+I + +K Sbjct: 184 TKEGLLLKEIHRDTSIEEVKSLTEANLIIPDDVK 217 >ref|NP_269686.1| putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit [Streptococcus pyogenes] gb|AAK34407.1| putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit [Streptococcus pyogenes M1 GAS] Length = 219 Score = 276 bits (705), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 142/209 (67%), Positives = 163/209 (77%), Gaps = 1/209 (0%) Query: 3 MDKAELQNMIAKRVAQELKDGELVNLGIGLPTKVANFVSEEVHVTFHSENGFVGLGPAQG 62 + K E+Q IAKRVAQEL+ LVNLGIGLPTKVAN++ E V +T SENGFVGL Sbjct: 8 LSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSENGFVGL-TGLT 66 Query: 63 EEITDPTIVNAGGQYVTINPNGCFFDSATSFGIIRGGHVDLTVLGALQVDEKGNIANYMI 122 ++ DPTIVNAGGQ V+I P G FFDS+TSFGIIRGGHV TVLGALQVD++ +IANY+I Sbjct: 67 DDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLI 126 Query: 123 PGKMVPGMGGAMDLLTGAKKVIVAMEHTSQGKAKILKECTLPLTAKNAVDLIITEMAVIE 182 PGKMVPGMGGAMDLL GAKKVIVAMEHT++GKAKIL +CTLPLTA+N V+LIITEM V E Sbjct: 127 PGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQNVVNLIITEMGVFE 186 Query: 183 VTPEGFLLQEINSAYTLEEVLAATEAKLL 211 EG EIN YT E+V TE L+ Sbjct: 187 YQDEGLCALEINPDYTFEDVQNVTEVTLI 215 >ref|NP_607697.1| putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit [Streptococcus pyogenes MGAS8232] gb|AAL98196.1| putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit [Streptococcus pyogenes MGAS8232] Length = 219 Score = 274 bits (700), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 140/209 (66%), Positives = 163/209 (77%), Gaps = 1/209 (0%) Query: 3 MDKAELQNMIAKRVAQELKDGELVNLGIGLPTKVANFVSEEVHVTFHSENGFVGLGPAQG 62 + K E+Q IAKR+AQEL+ LVNLGIGLPTKVAN++ + V +T SENGFVGL Sbjct: 8 LSKEEIQTRIAKRIAQELEHNTLVNLGIGLPTKVANYIPKGVTITLQSENGFVGL-TGLT 66 Query: 63 EEITDPTIVNAGGQYVTINPNGCFFDSATSFGIIRGGHVDLTVLGALQVDEKGNIANYMI 122 ++ DPTIVNAGGQ V+I P G FFDS+TSFGIIRGGHV TVLGALQVD++ +IANY+I Sbjct: 67 DDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLI 126 Query: 123 PGKMVPGMGGAMDLLTGAKKVIVAMEHTSQGKAKILKECTLPLTAKNAVDLIITEMAVIE 182 PGKMVPGMGGAMDLL GAKKVIVAMEHT++GKAKIL +CTLPLTA+N V+LIITEM V E Sbjct: 127 PGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQNVVNLIITEMGVFE 186 Query: 183 VTPEGFLLQEINSAYTLEEVLAATEAKLL 211 EG EIN YT E+V TE L+ Sbjct: 187 YQDEGLCALEINPDYTFEDVQNVTEVTLI 215 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.315 0.134 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 316,508,364 Number of extensions: 13158400 Number of successful extensions: 22891 Number of sequences better than 1.0e-05: 256 Number of HSP's gapped: 22583 Number of HSP's successfully gapped: 256 Length of query: 220 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 99 Effective length of database: 428,710,599 Effective search space: 42442349301 Effective search space used: 42442349301 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 123 (52.0 bits)