BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0307.0033.p (300 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00188580.1| hypothetical protein Rxyl016701 [Rubrobacter ... 188 2e-46 ref|NP_462161.1| tartronate semialdehyde reductase [Salmonella t... 187 3e-46 ref|NP_708925.1| putative dehydrogenase [Shigella flexneri 2a st... 186 6e-46 ref|NP_342984.1| Oxidoreductase [Sulfolobus solfataricus] >gi|25... 185 1e-45 ref|NP_457634.1| 2-hydroxy-3-oxopropionate reductase [Salmonella... 185 1e-45 >ref|ZP_00188580.1| hypothetical protein Rxyl016701 [Rubrobacter xylanophilus DSM 9941] Length = 297 Score = 188 bits (477), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 106/292 (36%), Positives = 163/292 (55%), Gaps = 1/292 (0%) Query: 2 KQIGFIGLGTMGAPMASNLLRSGFEVTVYNRTASRSEPL-RAEGARVAATPQHAAEGKDV 60 +++GFIGLG MG PMA NL+R+G+ +TV+NRT ++E + GAR A +P+ A D+ Sbjct: 3 EKVGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGARTAKSPKEVAGQSDI 62 Query: 61 IITMISNDDSIREVFYGTGGILAVLKPGTTVVDSSTISPGLAKEIAAAVEERGGSFLDAP 120 IITM+ + + V G GG+L ++ G+ ++D STISP +A+++AA ERG S LDAP Sbjct: 63 IITMLPDSPDVESVVAGEGGVLEGMREGSLLIDMSTISPAVARQLAAKARERGASMLDAP 122 Query: 121 VTGSKPAAIEGTLVFMVGGSAGVIDQHRDIFDSMGRLLLHMGGNGSGAVAKLAHNAMVGI 180 V+G A EGTL MVGGS + R +F+ MG+ + H+G +G+G + K A+ +VG+ Sbjct: 123 VSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQIVKAANQIVVGL 182 Query: 181 HNVALAEGFSIAVKSGVPADKFLELVKNGSAGSKQAELKGQKIIDNDFSNQFXXXXXXXX 240 A+ E + ++ GV K E++ G A ++ E+K +K + DF Sbjct: 183 TIEAVCEALVLGLRGGVEPQKIFEVLCGGLAANRVMEVKREKFLSRDFRPGGKARFHRKD 242 Query: 241 XXXXXXXXXXXGVPSPMLGVAKSMFQAGYNHGYGDEDLSAVVKSYEEWIGQK 292 GV P + + +F A G GD D SA++ EE G + Sbjct: 243 LGIALNTGREYGVALPAAALVEQLFGALEAKGRGDLDHSALLLLVEELSGHQ 294 >ref|NP_462161.1| tartronate semialdehyde reductase [Salmonella typhimurium LT2] gb|AAL22120.1| tartronate semialdehyde reductase (TSAR) [Salmonella typhimurium LT2] Length = 296 Score = 187 bits (474), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 102/286 (35%), Positives = 160/286 (55%) Query: 3 QIGFIGLGTMGAPMASNLLRSGFEVTVYNRTASRSEPLRAEGARVAATPQHAAEGKDVII 62 ++GFIGLG MG PM+ NLL++G+ + V +R + A GA A+T + AE DVII Sbjct: 4 KVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVII 63 Query: 63 TMISNDDSIREVFYGTGGILAVLKPGTTVVDSSTISPGLAKEIAAAVEERGGSFLDAPVT 122 TM+ N ++EV G GI+ KPGT ++D S+I+P ++EI+ A++ +G LDAPV+ Sbjct: 64 TMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPVS 123 Query: 123 GSKPAAIEGTLVFMVGGSAGVIDQHRDIFDSMGRLLLHMGGNGSGAVAKLAHNAMVGIHN 182 G +P AI+GTL MVGG + D++ D+ +M ++H G G+G V KLA+ +V ++ Sbjct: 124 GGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALNI 183 Query: 183 VALAEGFSIAVKSGVPADKFLELVKNGSAGSKQAELKGQKIIDNDFSNQFXXXXXXXXXX 242 A++E ++A K+GV D + ++ G AGS + K ++D +F F Sbjct: 184 AAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLA 243 Query: 243 XXXXXXXXXGVPSPMLGVAKSMFQAGYNHGYGDEDLSAVVKSYEEW 288 G P+ M QA G+G++D SA+ YE+ Sbjct: 244 NALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSALACYYEKL 289 >ref|NP_708925.1| putative dehydrogenase [Shigella flexneri 2a str. 301] ref|NP_838636.1| putative dehydrogenase [Shigella flexneri 2a str. 2457T] gb|AAN44632.1| putative dehydrogenase [Shigella flexneri 2a str. 301] gb|AAP18447.1| putative dehydrogenase [Shigella flexneri 2a str. 2457T] Length = 299 Score = 186 bits (472), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 103/286 (36%), Positives = 158/286 (55%) Query: 3 QIGFIGLGTMGAPMASNLLRSGFEVTVYNRTASRSEPLRAEGARVAATPQHAAEGKDVII 62 ++GFIGLG MG PM+ NLL++G+ + V +R + A GA A+T + AE DVII Sbjct: 7 KVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVII 66 Query: 63 TMISNDDSIREVFYGTGGILAVLKPGTTVVDSSTISPGLAKEIAAAVEERGGSFLDAPVT 122 TM+ N ++EV G GI+ KPGT ++D S+I+P ++EI+ A++ +G LDAPV+ Sbjct: 67 TMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVS 126 Query: 123 GSKPAAIEGTLVFMVGGSAGVIDQHRDIFDSMGRLLLHMGGNGSGAVAKLAHNAMVGIHN 182 G +P AI+GTL MVGG + D++ D+ +M ++H G G+G V KLA+ +V ++ Sbjct: 127 GGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGAIGAGNVTKLANQVIVALNI 186 Query: 183 VALAEGFSIAVKSGVPADKFLELVKNGSAGSKQAELKGQKIIDNDFSNQFXXXXXXXXXX 242 A++E ++A K+GV D + ++ G AGS + K ++D +F F Sbjct: 187 AAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLA 246 Query: 243 XXXXXXXXXGVPSPMLGVAKSMFQAGYNHGYGDEDLSAVVKSYEEW 288 G P+ M QA G G D SA+V YE+ Sbjct: 247 NALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALVCYYEKL 292 >ref|NP_342984.1| Oxidoreductase [Sulfolobus solfataricus] pir||G90314 oxidoreductase [imported] - Sulfolobus solfataricus gb|AAK41774.1| Oxidoreductase [Sulfolobus solfataricus] Length = 289 Score = 185 bits (469), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 102/287 (35%), Positives = 157/287 (54%) Query: 3 QIGFIGLGTMGAPMASNLLRSGFEVTVYNRTASRSEPLRAEGARVAATPQHAAEGKDVII 62 ++GFIGLG MG PMASNLL++G+++TVYNRT ++E L GA+VA +P+ AE +++I Sbjct: 2 KVGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGKMGAKVAHSPKEVAEVSEIVI 61 Query: 63 TMISNDDSIREVFYGTGGILAVLKPGTTVVDSSTISPGLAKEIAAAVEERGGSFLDAPVT 122 +M+++ + EV +G G++ K G VD ST SP AK++ + E G FLDAPVT Sbjct: 62 SMVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVT 121 Query: 123 GSKPAAIEGTLVFMVGGSAGVIDQHRDIFDSMGRLLLHMGGNGSGAVAKLAHNAMVGIHN 182 G A EGTL MVGG V + IF +MG+ ++H+G GSG KL + +V ++ Sbjct: 122 GGDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVVALNM 181 Query: 183 VALAEGFSIAVKSGVPADKFLELVKNGSAGSKQAELKGQKIIDNDFSNQFXXXXXXXXXX 242 V++ EG +A G+ DK ++ G+A S + KI+ D + F Sbjct: 182 VSVVEGLLLARSLGIDDDKLFSVLSTGAANSFTVQYYLPKIMKGDLNPGFKAAHLKKDLK 241 Query: 243 XXXXXXXXXGVPSPMLGVAKSMFQAGYNHGYGDEDLSAVVKSYEEWI 289 +P +A ++ A + G G+ +VK YE+ + Sbjct: 242 YAMEIANSKSLPLLGTSLALQLYNAMVSLGIGELGTQGLVKVYEKLV 288 >ref|NP_457634.1| 2-hydroxy-3-oxopropionate reductase [Salmonella enterica subsp. enterica serovar Typhi] ref|NP_806847.1| 2-hydroxy-3-oxopropionate reductase [Salmonella enterica subsp. enterica serovar Typhi Ty2] pir||AE0897 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) emb|CAD07771.1| 2-hydroxy-3-oxopropionate reductase [Salmonella enterica subsp. enterica serovar Typhi] gb|AAO70707.1| 2-hydroxy-3-oxopropionate reductase [Salmonella enterica subsp. enterica serovar Typhi Ty2] Length = 294 Score = 185 bits (469), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 101/286 (35%), Positives = 159/286 (55%) Query: 3 QIGFIGLGTMGAPMASNLLRSGFEVTVYNRTASRSEPLRAEGARVAATPQHAAEGKDVII 62 ++GFIGLG MG PM+ NLL++G+ + V +R + A GA A+T + AE D II Sbjct: 2 KVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDAII 61 Query: 63 TMISNDDSIREVFYGTGGILAVLKPGTTVVDSSTISPGLAKEIAAAVEERGGSFLDAPVT 122 TM+ N ++EV G GI+ KPGT ++D S+I+P ++EI+ A++ +G LDAPV+ Sbjct: 62 TMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPVS 121 Query: 123 GSKPAAIEGTLVFMVGGSAGVIDQHRDIFDSMGRLLLHMGGNGSGAVAKLAHNAMVGIHN 182 G +P AI+GTL MVGG + D++ D+ +M ++H G G+G V KLA+ +V ++ Sbjct: 122 GGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALNI 181 Query: 183 VALAEGFSIAVKSGVPADKFLELVKNGSAGSKQAELKGQKIIDNDFSNQFXXXXXXXXXX 242 A++E ++A K+GV D + ++ G AGS + K ++D +F F Sbjct: 182 AAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLA 241 Query: 243 XXXXXXXXXGVPSPMLGVAKSMFQAGYNHGYGDEDLSAVVKSYEEW 288 G P+ M QA G+G++D SA+ YE+ Sbjct: 242 NALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSALACYYEKL 287 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.315 0.133 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 418,223,983 Number of extensions: 16684803 Number of successful extensions: 43937 Number of sequences better than 1.0e-05: 1370 Number of HSP's gapped: 42966 Number of HSP's successfully gapped: 1372 Length of query: 300 Length of database: 757,237,578 Length adjustment: 125 Effective length of query: 175 Effective length of database: 417,850,203 Effective search space: 73123785525 Effective search space used: 73123785525 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 125 (52.8 bits)