BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0303.0006.p (582 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00103923.1| COG0642: Signal transduction histidine kinase... 190 1e-46 ref|NP_976755.1| sensor histidine kinase, putative [Bacillus cer... 189 1e-46 ref|ZP_00097754.1| COG0642: Signal transduction histidine kinase... 184 7e-45 ref|NP_835115.1| Sporulation kinase [Bacillus cereus ATCC 14579]... 182 1e-44 gb|AAA22800.1| SpoIIJ protein (gtg start codon) 155 2e-36 >ref|ZP_00103923.1| COG0642: Signal transduction histidine kinase [Desulfitobacterium hafniense] Length = 638 Score = 190 bits (482), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 105/240 (43%), Positives = 154/240 (64%), Gaps = 5/240 (2%) Query: 327 VLIVQDLTEEEKFRSELDNVERLTLVGQMAAGITHEIRNPMAVVRGFLQLM--REKSPGE 384 +L+ QD+TE++ E+ +ERL L+GQMAAGI HEIRNPM VRG+LQ + ++K E Sbjct: 399 LLVSQDITEKKCLEKEMARLERLDLIGQMAAGIGHEIRNPMTTVRGYLQYISKKDKYADE 458 Query: 385 MDSYYQIVIEELDRANGIINDFLSLAQSRISDKEPVQLHHIIKELAPLLWADANLRGQSV 444 ++++ Q++IEELDRAN II ++LSL+Q R+ D + + L+ II+ L P+L + +S+ Sbjct: 459 IETF-QLMIEELDRANEIITEYLSLSQDRVVDFKRINLNTIIQHLYPILSVHTKMEDKSI 517 Query: 445 EXXXXXXXXXXXXXXREIKQLILNLARNGMEAMEPKGELLLETHFNENKVELIIQDTGSG 504 E +E+ QLILNL RNG+EAM KG+L + T+ + V L ++D G G Sbjct: 518 ELNLGSLPELYLDK-KELCQLILNLVRNGLEAMPIKGKLTISTYIQQGNVILEVEDQGRG 576 Query: 505 IPQSQLEKLFVPFYTTKNQGTGLGLPLCLSIAERHHGSIRVESQVGKGTAFIVSFPYVQE 564 IP +K+ PF+TTK GTGLG+ +C SIAERH+ I ++S +GT V F +E Sbjct: 577 IPNEIKDKVGTPFFTTKLNGTGLGMAICYSIAERHNALIDLQSG-PQGTKVRVKFQAAEE 635 >ref|NP_976755.1| sensor histidine kinase, putative [Bacillus cereus ATCC 10987] gb|AAS39363.1| sensor histidine kinase, putative [Bacillus cereus ATCC 10987] Length = 676 Score = 189 bits (481), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 99/235 (42%), Positives = 153/235 (65%), Gaps = 4/235 (1%) Query: 329 IVQDLTEEEKFRSELDNVERLTLVGQMAAGITHEIRNPMAVVRGFLQLMREKSPGE-MDS 387 I +++TE++++ EL + + L+GQMAAGI+HEIRNPM VRGFLQL++E++ E ++ Sbjct: 439 ICKNITEKKQYEQELKRLSNIELIGQMAAGISHEIRNPMTTVRGFLQLLKEENNYEKHNN 498 Query: 388 YYQIVIEELDRANGIINDFLSLAQSRISDKEPVQLHHIIKELAPLLWADANLRGQSVEXX 447 Y+ +++EELDRAN II +FLS+ ++ SD + + L+ II+++ PL+ D + + + ++ Sbjct: 499 YFNLMVEELDRANSIITEFLSIGNTKKSDLQMLDLNSIIRDIIPLIKIDTHNQNKYIQ-V 557 Query: 448 XXXXXXXXXXXXREIKQLILNLARNGMEAMEPKGELLLETHFNENK-VELIIQDTGSGIP 506 EI+QL++NL RNG+EAM L + T+ K V L ++D G+GI Sbjct: 558 DTNDVPELLLNRNEIRQLLMNLYRNGLEAMSTGKTLTISTYKEGQKCVVLAVRDEGNGIR 617 Query: 507 QSQLEKLFVPFYTTKNQGTGLGLPLCLSIAERHHGSIRVESQVGKGTAFIVSFPY 561 LEKL PFYTTK+ GTGLGL +C +IA RH+ I +++ +GT F V F Y Sbjct: 618 PEVLEKLGTPFYTTKDNGTGLGLGVCYAIAARHNAKIEIQTG-SEGTTFFVKFNY 671 >ref|ZP_00097754.1| COG0642: Signal transduction histidine kinase [Desulfitobacterium hafniense] Length = 531 Score = 184 bits (466), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 101/232 (43%), Positives = 144/232 (62%), Gaps = 3/232 (1%) Query: 330 VQDLTEEEKFRSELDNVERLTLVGQMAAGITHEIRNPMAVVRGFLQLMREKSPG-EMDSY 388 + D+ E + +E+ ++RL LVGQMAAGI HEIRNPM VRG+LQLM EK+ S Sbjct: 293 LTDIKELKSLHTEMVRLDRLNLVGQMAAGIAHEIRNPMTTVRGYLQLMGEKTQDMGQKST 352 Query: 389 YQIVIEELDRANGIINDFLSLAQSRISDKEPVQLHHIIKELAPLLWADANLRGQSVEXXX 448 +IEELDRAN II +FL+LA+S + + L+ +++ L PL+ AD+ + + + Sbjct: 353 LHFMIEELDRANTIIKEFLTLAKSHKPNYQIFNLNTLLQNLHPLIEADSFTQNKQIRFTP 412 Query: 449 XXXXXXXXXXXREIKQLILNLARNGMEAMEPKGELLLETHFNENKVELIIQDTGSGIPQS 508 ++I Q++LN+ RNG+EAM G L ++T+ + V L I+D G GIP+ Sbjct: 413 GDIPDIEISP-KDITQMVLNICRNGLEAMSEGGCLTIQTYKKNHTVVLAIKDEGHGIPKE 471 Query: 509 QLEKLFVPFYTTKNQGTGLGLPLCLSIAERHHGSIRVESQVGKGTAFIVSFP 560 LEKL PF+TTK GTGLGL +C IA+ H+ I V S +GT F++SFP Sbjct: 472 LLEKLGTPFFTTKESGTGLGLSICYKIAKSHNARIDVLSS-PEGTQFLISFP 522 >ref|NP_835115.1| Sporulation kinase [Bacillus cereus ATCC 14579] gb|AAP12316.1| Sporulation kinase [Bacillus cereus ATCC 14579] Length = 348 Score = 182 bits (463), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 99/235 (42%), Positives = 149/235 (63%), Gaps = 4/235 (1%) Query: 329 IVQDLTEEEKFRSELDNVERLTLVGQMAAGITHEIRNPMAVVRGFLQLMREKSPGE-MDS 387 I +++TE++K+ EL + + L+GQMAAGI+HEIRNPM V GFLQL++E++ E + Sbjct: 111 IFKNITEKKKYEQELKRLSNIDLIGQMAAGISHEIRNPMTTVLGFLQLLKEENTYEKHNK 170 Query: 388 YYQIVIEELDRANGIINDFLSLAQSRISDKEPVQLHHIIKELAPLLWADANLRGQSVEXX 447 Y+ ++IEEL+RAN II +FLS+ +R D + + L+ II+++ PL+ D + + ++ Sbjct: 171 YFHLMIEELNRANSIITEFLSMGNTRKLDLQMLDLNSIIRDIIPLIKIDTYNQNKYIQ-V 229 Query: 448 XXXXXXXXXXXXREIKQLILNLARNGMEAMEPKGELLLETHFN-ENKVELIIQDTGSGIP 506 EI+QL++NL RNG+EAM L + T+ +N V L ++D G GI Sbjct: 230 DTNDIPELLLNRNEIRQLLMNLYRNGLEAMNTGKVLTISTYKEGQNCVVLAVRDQGKGIR 289 Query: 507 QSQLEKLFVPFYTTKNQGTGLGLPLCLSIAERHHGSIRVESQVGKGTAFIVSFPY 561 LEKL PFYTTK+ GTGLGL +C +IA RH+ I +++ +GT F V F Y Sbjct: 290 PEVLEKLGTPFYTTKDNGTGLGLGVCYAIAARHNAKIEIQTG-SEGTTFFVKFNY 343 >gb|AAA22800.1| SpoIIJ protein (gtg start codon) Length = 606 Score = 155 bits (393), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 87/234 (37%), Positives = 138/234 (58%), Gaps = 2/234 (0%) Query: 328 LIVQDLTEEEKFRSELDNVERLTLVGQMAAGITHEIRNPMAVVRGFLQLMREKSPGEMDS 387 +I++D++E ++ + E+L++ GQ+AAGI HEIRNP+ ++GFLQLM+ G + Sbjct: 372 VILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGN-EH 430 Query: 388 YYQIVIEELDRANGIINDFLSLAQSRISD-KEPVQLHHIIKELAPLLWADANLRGQSVEX 446 Y+ IV EL R I+++ L LA+ + + KE + L +I E++ LL ANL G + Sbjct: 431 YFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRT 490 Query: 447 XXXXXXXXXXXXXREIKQLILNLARNGMEAMEPKGELLLETHFNENKVELIIQDTGSGIP 506 ++KQ+ +NL +N +E+M G + + +E+ V + ++D G GIP Sbjct: 491 SYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIP 550 Query: 507 QSQLEKLFVPFYTTKNQGTGLGLPLCLSIAERHHGSIRVESQVGKGTAFIVSFP 560 + L ++ PF TTK +GTGLGL + +I E H G I V+S KGTAF +SFP Sbjct: 551 EKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFP 604 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.139 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 790,126,144 Number of extensions: 31558688 Number of successful extensions: 101690 Number of sequences better than 1.0e-05: 3838 Number of HSP's gapped: 98206 Number of HSP's successfully gapped: 3851 Length of query: 582 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 451 Effective length of database: 401,559,609 Effective search space: 181103383659 Effective search space used: 181103383659 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 129 (54.3 bits)