BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0081.p (748 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_713255.1| surface protein Lk90-like protein [Leptospira i... 97 2e-18 gb|AAO65920.1| putative immunoglobulin-like protein A [Leptospir... 82 7e-14 dbj|BAD06007.1| bacterial immunogloblin [Leptospira interrogans ... 79 4e-13 gb|AAN52495.1| putative surface protein [Leptospira interrogans ... 79 5e-13 gb|AAP04735.1| LigA [Leptospira kirschneri serovar grippotyphosa] 76 3e-12 >ref|NP_713255.1| surface protein Lk90-like protein [Leptospira interrogans serovar lai str. 56601] gb|AAN50273.1| surface protein Lk90-like protein [Leptospira interrogans serovar lai str. 56601] gb|AAP92092.1| LigC [Leptospira interrogans serovar pomona] Length = 1956 Score = 97.1 bits (240), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 162/686 (23%), Positives = 288/686 (41%), Gaps = 69/686 (10%) Query: 89 GLLTAVNTGTAMITATYNNAIATLEVSVTHPFKELTLERSSDGNYKLGDSEESLQVKAKV 148 GL++ ++ G+ IT++Y + ++L V+V+ ++ +Y LG ++ Sbjct: 225 GLVSGLSPGSTSITSSYGSKTSSLNVTVSAATLSSIAVTPANSSYPLGKVQQ-----YTA 279 Query: 149 VGGESATSVKDVSADADWTSSNPNVLTIED-----GKITLVGEGKSTITAKYKGLTATFK 203 +G S S +D++ W S N +V TI++ G +T G + I A G+T Sbjct: 280 IGTYSNQSTQDLTNQVSWASLNTSVATIDNSASSKGLLTTQSTGSANIIATLGGITGQ-- 337 Query: 204 AVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAMTKATESSPEKDIAADANWTTSN 263 Q+ ++ VL T + + L+A T DI + W++S Sbjct: 338 --TQVNVTSAVLTSI---TITPANPSIANGRTLYLTA-TGVFSDGTVSDITSQVTWSSSL 391 Query: 264 ESIAKVD-----AGKITIEGTGKAVITASYLGVSKSVDIYV-RAPYEALLLNPEGDQTLF 317 S+A D +G+I+ G G ITA+ G+ ++ + V A E++ + + ++ Sbjct: 392 TSVATADNSAGLSGRISGVGVGSTNITAAIGGIDITISLNVTNATLESIQVVSD-SHSIA 450 Query: 318 LGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTV 377 G S V++ + SSQN S + W+S N +GT Sbjct: 451 RGTSTFVQAIGVYSDGSSQNISDQVAWNSSNSSILQISNLNAVPKREIQSPSSGGLGTAR 510 Query: 378 IKGEYLGVSKSFKLTV-LPTLTELTADKTEQELFTADSESLP-KVTGTKYDGTKLEISDQ 435 I +S ++V TL + T + A ++P TG DG+ ++ Q Sbjct: 511 ITATLEAISAYTDISVNAATLVSIEVSPTNPSV--AAGLTIPFTATGVYTDGSNQNLTSQ 568 Query: 436 IEWTSADEEIVRIKD-----GKLVGGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXX 490 + W S++ I + G +G AGT + ++A+ A+ S + Sbjct: 569 VTWNSSNTNRATISNANGTQGIALGSSAGT---------TNISATLGAVTSSATTLTVTN 619 Query: 491 XXXXXXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAG 550 I P P S+ +G L +G D+T ++ W + S+ A+G Sbjct: 620 AVLNSITITPSIP-SIAVGRSLNLT-ATGTYSDGSNQDLTTSVAWTSADSSIASVDNASG 677 Query: 551 KTMK--GLSKGSATLKGTYSNKTISIPVTIEQKV---VKLLVEPSVLEMNIKASKSIKVT 605 + + G+++G+ + T + +I T+ V +++ +E S + +++I T Sbjct: 678 RQGQATGVTQGNTQISSTLGGVSSTISFTVNAAVLDSIQVTLEDSPIAKG-TFTRAI-AT 735 Query: 606 GTFSNGRTANFSGAMNWESSNTAVATV----RGTSVKAVDE--------GTATLTGSYQG 653 G FS+G N S + W+SS T V + G K ++ GT+ +T + G Sbjct: 736 GVFSDGSNLNISDQVVWDSSQTNVIQLGVLETGPKKKLMNSPANGNSTTGTSRITATLGG 795 Query: 654 ITATVKITVV-PKLTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPS 712 ++ +TV+ P LT + + T +A G +Q T +Y G+ +T S W SS P+ Sbjct: 796 VSGYADLTVIAPSLTSIQIDPTHPSVANGLTQNFTATGVYSDGSNQNLTDSVTWASSNPA 855 Query: 713 VAKIS-ASGIITAVGKGTTSIKGKYN 737 VA IS ASG GK TT G N Sbjct: 856 VATISNASG---TNGKATTLQTGSTN 878 Score = 75.1 bits (183), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 136/677 (20%), Positives = 280/677 (41%), Gaps = 49/677 (7%) Query: 65 SSKRDITAAAIWTSSNTNVVK-VANGLLTAVNTGTAMITATYNNAIATLEVSVTHP-FKE 122 ++ RD+++ W+S++++++K + +N G+ + ++ AT ++VT + Sbjct: 110 NTHRDVSSEGSWSSTDSSILKLLTQSQFKGMNLGSGNVNVSFQGKNATTTLTVTSAVLSD 169 Query: 123 LTLERSSDGN-YKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTIE-DGK 180 LT+ + G+ +G Q K + + + +T V A W ++ + G Sbjct: 170 LTVTCVNQGSPLPVGIDR---QCKLEGIFSDGSTQVLTSDPSASWNIIQSSIAGVNTTGL 226 Query: 181 ITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSA 240 ++ + G ++IT+ Y T++ V SA L A A L VQ Sbjct: 227 VSGLSPGSTSITSSYGSKTSSLNVTV----SAATLSSIAVTPANSSYPL----GKVQQYT 278 Query: 241 MTKATESSPEKDIAADANWTTSNESIAKVDA-----GKITIEGTGKAVITASYLGVSKSV 295 + +D+ +W + N S+A +D G +T + TG A I A+ G++ Sbjct: 279 AIGTYSNQSTQDLTNQVSWASLNTSVATIDNSASSKGLLTTQSTGSANIIATLGGITGQT 338 Query: 296 DIYV-RAPYEALLLNPEGDQTLFLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXX 354 + V A ++ + P + ++ G +L + + + + + + + WSS Sbjct: 339 QVNVTSAVLTSITITPA-NPSIANGRTLYLTATGVFSDGTVSDITSQVTWSS----SLTS 393 Query: 355 XXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFKLTVLPTLTELTADKTEQELFTADS 414 VG+T I G+ + L V E ++ + Sbjct: 394 VATADNSAGLSGRISGVGVGSTNITAAIGGIDITISLNVTNATLESIQVVSDSHSIARGT 453 Query: 415 ESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVGGKAGTVTLTGKIKNSTVAA 474 + + G DG+ ISDQ+ W S++ I++I + V + +G + + + A Sbjct: 454 STFVQAIGVYSDGSSQNISDQVAWNSSNSSILQISNLNAVPKREIQSPSSGGLGTARITA 513 Query: 475 SPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIK 534 + AI S + P +P S+ G P V +G ++T + Sbjct: 514 TLEAI-SAYTDISVNAATLVSIEVSPTNP-SVAAGLTIPFT-ATGVYTDGSNQNLTSQVT 570 Query: 535 WEFSGSNAVVKQTAAGKTMKGLSKG--------SATLKGTYSNKTISIPVTIEQKVVK-L 585 W S +N A G +G++ G SATL S+ T +T+ V+ + Sbjct: 571 WNSSNTNRATISNANGT--QGIALGSSAGTTNISATLGAVTSSATT---LTVTNAVLNSI 625 Query: 586 LVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVK-----AV 640 + PS+ + + S ++ TGT+S+G + + ++ W S+++++A+V S + V Sbjct: 626 TITPSIPSIAVGRSLNLTATGTYSDGSNQDLTTSVAWTSADSSIASVDNASGRQGQATGV 685 Query: 641 DEGTATLTGSYQGITATVKITV-VPKLTKLTVSETRLKLAPGASQGVVVTALYDTGNTAT 699 +G ++ + G+++T+ TV L + V+ +A G + T ++ G+ Sbjct: 686 TQGNTQISSTLGGVSSTISFTVNAAVLDSIQVTLEDSPIAKGTFTRAIATGVFSDGSNLN 745 Query: 700 VTGSTVWTSSKPSVAKI 716 ++ VW SS+ +V ++ Sbjct: 746 ISDQVVWDSSQTNVIQL 762 Score = 66.2 bits (160), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 91/383 (23%), Positives = 163/383 (42%), Gaps = 62/383 (16%) Query: 382 YLGVSKSFKLTVLPTLTELTADKTEQEL----FTADSESLPKVTGTKYDGTKLEISDQIE 437 +LGV+ L P+ TEL D+ E + F + T D T ++S + Sbjct: 65 FLGVNN--PLESEPSETEL--DRIEISVPNSSFARGTTLHLNATAIYKDNTHRDVSSEGS 120 Query: 438 WTSADEEIVRIKDGKLVGGK---AGTVTLTGKIKNSTVAAS-PSAIRSKSXXXXXXXXXX 493 W+S D I+++ G +G V ++ + KN+T + SA+ S Sbjct: 121 WSSTDSSILKLLTQSQFKGMNLGSGNVNVSFQGKNATTTLTVTSAVLS------------ 168 Query: 494 XXXXIGPEDPQSLVIGEEKPLP-------GVKAVLENGDE--LDVTPTIKWEFSGSNAVV 544 D + + PLP ++ + +G L P+ W ++ Sbjct: 169 --------DLTVTCVNQGSPLPVGIDRQCKLEGIFSDGSTQVLTSDPSASWN------II 214 Query: 545 KQTAAGKT----MKGLSKGSATLKGTYSNKTISIPVTIEQKVV-KLLVEPSVLEMNIKAS 599 + + AG + GLS GS ++ +Y +KT S+ VT+ + + V P+ + Sbjct: 215 QSSIAGVNTTGLVSGLSPGSTSITSSYGSKTSSLNVTVSAATLSSIAVTPANSSYPLGKV 274 Query: 600 KSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTS-----VKAVDEGTATLTGSYQGI 654 + GT+SN T + + ++W S NT+VAT+ ++ + G+A + + GI Sbjct: 275 QQYTAIGTYSNQSTQDLTNQVSWASLNTSVATIDNSASSKGLLTTQSTGSANIIATLGGI 334 Query: 655 TATVKITVVPK-LTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPSV 713 T ++ V LT +T++ +A G + + T ++ G + +T W+SS SV Sbjct: 335 TGQTQVNVTSAVLTSITITPANPSIANGRTLYLTATGVFSDGTVSDITSQVTWSSSLTSV 394 Query: 714 A----KISASGIITAVGKGTTSI 732 A SG I+ VG G+T+I Sbjct: 395 ATADNSAGLSGRISGVGVGSTNI 417 Score = 60.1 bits (144), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 142/650 (21%), Positives = 253/650 (38%), Gaps = 94/650 (14%) Query: 66 SKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHPF 120 S +++T+ W SSNTN ++N G+ + GT I+AT +VT Sbjct: 561 SNQNLTSQVTWNSSNTNRATISNANGTQGIALGSSAGTTNISATLG--------AVTSSA 612 Query: 121 KELTLERSSDGNYKLGDSEESLQVKAKV----VGGESATSVKDVSADADWTSSNPNVLTI 176 LT+ + + + S S+ V + G S S +D++ WTS++ ++ ++ Sbjct: 613 TTLTVTNAVLNSITITPSIPSIAVGRSLNLTATGTYSDGSNQDLTTSVAWTSADSSIASV 672 Query: 177 ED-----GKITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLV 231 ++ G+ T V +G + I++ G+++T V A VL +++ + Sbjct: 673 DNASGRQGQATGVTQGNTQISSTLGGVSSTISFTVN----AAVLD---------SIQVTL 719 Query: 232 GDSPVQLSAMTKATESSPEKD-----IAADANWTTSNESIAKVDA--------------- 271 DSP+ T+A + D I+ W +S ++ ++ Sbjct: 720 EDSPIAKGTFTRAIATGVFSDGSNLNISDQVVWDSSQTNVIQLGVLETGPKKKLMNSPAN 779 Query: 272 GKITIEGTGKAVITASYLGVSKSVDIYVRAP-YEALLLNPEGDQTLF-LGESLRVKSFVR 329 G T TG + ITA+ GVS D+ V AP ++ ++P L ++ Sbjct: 780 GNST---TGTSRITATLGGVSGYADLTVIAPSLTSIQIDPTHPSVANGLTQNFTATGVYS 836 Query: 330 DAVNSSQNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSF 389 D N QN + W+S N G+T I V+ Sbjct: 837 DGSN--QNLTDSVTWASSNPAVATISNASGTNGKATTLQ----TGSTNISASLGAVTSDP 890 Query: 390 KLTVL--PTLTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVR 447 + + TLT +T T TG DG+ +++ Q+ W S++ + Sbjct: 891 SVLTITNATLTNITIAPTSSFNIAKGLNQDFVATGYYTDGSSRDLTTQVTWNSSNASVST 950 Query: 448 IKDGKLVGGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLV 507 I + G+ V ++ ++AS S + I P D S+ Sbjct: 951 ISNANGTQGRMAAV----DTGSTNISASLGGTSSPNTNVTVTSAVLNSIQISPAD-ISVA 1005 Query: 508 IGEEKPLPGVKAVLENGDELDVTPTIKWEFSG------SNAVVKQTAAGKTMKGLSKGSA 561 G K + V + LDVT + W S SNA + A G S +A Sbjct: 1006 KGNTKVYTAI-GVYSDFSTLDVTSQVTWTSSSVSVATISNASGHEGFATTVGTGTSTITA 1064 Query: 562 TLKGTYSNKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMN 621 TL G ++ ++++ + +V L V P+ + + +K+ TGT+S+G + + + Sbjct: 1065 TLGGISNSTSLTVTAAV---LVSLSVGPTNSFVYMTQTKNFTATGTYSDGTMQDLTTQVT 1121 Query: 622 WESSNTAVATV--------RGTSVKAVDEGTATLTGSYQGITATVKITVV 663 W SS+T + T+ R T + A G TLT + I+ +TV+ Sbjct: 1122 WTSSDTTLGTISNSFGIEGRATGIAA---GAVTLTATLGSISGNTSLTVI 1168 Score = 57.0 bits (136), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 91/386 (23%), Positives = 155/386 (40%), Gaps = 38/386 (9%) Query: 374 GTTVIKGEYLGVSKSFKLTVLPTLTELTADKTEQELFTADSESLPKVTGTKYDGTKLEIS 433 G T I GVS + TV + + E + + TG DG+ L IS Sbjct: 688 GNTQISSTLGGVSSTISFTVNAAVLDSIQVTLEDSPIAKGTFTRAIATGVFSDGSNLNIS 747 Query: 434 DQIEWTSADEEIVRI------KDGKLVGGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXX 487 DQ+ W S+ ++++ KL+ A + TG S + A+ + S Sbjct: 748 DQVVWDSSQTNVIQLGVLETGPKKKLMNSPANGNSTTGT---SRITATLGGV-SGYADLT 803 Query: 488 XXXXXXXXXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIKWEFSGSNAVVKQT 547 I P P S+ G + V +G ++T ++ W S Sbjct: 804 VIAPSLTSIQIDPTHP-SVANGLTQNFT-ATGVYSDGSNQNLTDSVTWASSNPAVATISN 861 Query: 548 AAGKTMKGLSKGSATLKGTYSNKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKV--- 604 A+G K + TL+ +N + S+ V + ++ + I + S + Sbjct: 862 ASGTNGK-----ATTLQTGSTNISASLGAVTSDPSVLTITNATLTNITIAPTSSFNIAKG 916 Query: 605 -------TGTFSNGRTANFSGAMNWESSNTAVATV---RGTS--VKAVDEGTATLTGSYQ 652 TG +++G + + + + W SSN +V+T+ GT + AVD G+ ++ S Sbjct: 917 LNQDFVATGYYTDGSSRDLTTQVTWNSSNASVSTISNANGTQGRMAAVDTGSTNISASLG 976 Query: 653 GITA-TVKITVVPK-LTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSK 710 G ++ +TV L + +S + +A G ++ +Y +T VT WTSS Sbjct: 977 GTSSPNTNVTVTSAVLNSIQISPADISVAKGNTKVYTAIGVYSDFSTLDVTSQVTWTSSS 1036 Query: 711 PSVAKISAS----GIITAVGKGTTSI 732 SVA IS + G T VG GT++I Sbjct: 1037 VSVATISNASGHEGFATTVGTGTSTI 1062 >gb|AAO65920.1| putative immunoglobulin-like protein A [Leptospira interrogans serovar copenhageni] gb|AAS69086.1| Ig-like repeat domain protein 1 [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130] Length = 1224 Score = 81.6 bits (200), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 153/678 (22%), Positives = 284/678 (41%), Gaps = 90/678 (13%) Query: 83 VVKVANGLLTAVNTGTAMITATYNNAIATLEVSVTHPFKELTLERSSDGNYKLGDSEESL 142 VV + + + +G+++I A YN + +++VT P +++ +S + G + Sbjct: 100 VVTIEGNRVRGIASGSSIIKAEYNGLYSEQKITVT-PAILNSIQVTS---LESGILPKGT 155 Query: 143 QVKAKVVGGESATSVKDVSADA--DWTSSNPNVLTIED-GKITLVGEGKSTITAKYKGLT 199 + +G S S +D+S + W+SSNP+++ ++D G + + G + I A ++ Sbjct: 156 NRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLVRVDDSGLASGINLGTAHIRASFQSKQ 215 Query: 200 ATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAMTKATES-----SPEKDIA 254 + V D + ++++ D + L K T + + +DI+ Sbjct: 216 GAEEMTV-------------GDAVLSQIQVTSNDLNIPLGKKQKLTATGIYSDNSNRDIS 262 Query: 255 ADANWTTSNESIAKV-DAGKITIEGTGKAVITASYLGVSKSVDIYVR-APYEALLLNPEG 312 + W +SN +IA + + G + TG ++AS + SV + V A ++ ++P Sbjct: 263 SSVIWNSSNSTIANIQNNGILETADTGIVTVSASSENIIGSVKLIVTPAALVSISVSPTN 322 Query: 313 DQTL-FLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXK 371 L E+ + D NS+ + + + W S N Sbjct: 323 STVAKGLQENFKATGIFTD--NSNSDITDQVTWDSSNTDILSISNASDSHGLASTLNQGN 380 Query: 372 AVGTTVIKGEYLGVSKSFKLT--------VLPTLTELTADKTEQELFTADSESLPKVTGT 423 T I G + S FK+T V PT T + T++ FTA G Sbjct: 381 VKVTASIGG--IQGSTDFKVTQAALTSIEVSPTRTSIAKGLTQK--FTA--------IGI 428 Query: 424 KYDGTKLEISDQIEWTSADE--EIVRIKDGKLVG--GKAGTVTLT---GKIK-NSTVAAS 475 D +K +I+DQ+ W S+ + + + K +G G T+T GK+ N+ Sbjct: 429 FTDNSKKDITDQVTWNSSSAIVSVSNLDNNKGLGKTNSVGNTTITATLGKVSGNTWFTVV 488 Query: 476 PSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIKW 535 P+ + S I P +P SL G + +N ++ D+T + W Sbjct: 489 PAVLTS--------------IQINPVNP-SLAKGLTQKFTATGIYSDNSNK-DITSAVTW 532 Query: 536 EFSGSNAVVKQTAAGKTM---KGLSKGSATLKGTYSNKTISIPVTI----EQKVVKLLVE 588 FS +++ + A K G + G+ +K T+ +S PV+ K+V++ + Sbjct: 533 -FSSDSSIATISNAQKNQGNAYGAATGATDIKATFGK--VSSPVSTLSVTAAKLVEIQIT 589 Query: 589 PSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVK-----AVDEG 643 P+ ++ K TG F++ ++ + + W SSNT + TV T+ K + +G Sbjct: 590 PAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTDILTVSNTNAKRGLGSTLKQG 649 Query: 644 TATLTGSYQGITATVKITVVPK-LTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTG 702 T +T S GI +V TV LT + VS TR +A G +Q T ++ + +T Sbjct: 650 TVKVTASMGGIEDSVDFTVTQATLTSIEVSPTRASIAKGMTQKFTATGIFTDHSKKNITE 709 Query: 703 STVWTSSKPSVAKISASG 720 W SS +++ ++A G Sbjct: 710 QVTWKSSSKALSMLNAPG 727 Score = 79.3 bits (194), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 173/737 (23%), Positives = 292/737 (39%), Gaps = 67/737 (9%) Query: 33 LNSIEFDSSAKVELTVGQTPKQLKVYASLEG---SSSKRDITAAA--IWTSSNTNVVKVA 87 LNSI+ S L G PK S G S +DI+ +W+SSN ++V+V Sbjct: 138 LNSIQVTS-----LESGILPKGTNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLVRVD 192 Query: 88 N-GLLTAVNTGTAMITATYNNAIATLEVSVTHPFKELTLERSSDGNYKLGDSEESLQVKA 146 + GL + +N GTA I A++ + E++V S+D N LG + K Sbjct: 193 DSGLASGINLGTAHIRASFQSKQGAEEMTVGDAVLSQIQVTSNDLNIPLGKKQ-----KL 247 Query: 147 KVVGGESATSVKDVSADADWTSSNPNVLTIEDGKITLVGE-GKSTITAKYKGLTATFKAV 205 G S S +D+S+ W SSN + I++ I + G T++A + + + K + Sbjct: 248 TATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASSENIIGSVKLI 307 Query: 206 VQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAMTKAT---ESSPEKDIAADANWTTS 262 V P + + + ++ V + L KAT + DI W +S Sbjct: 308 VT-PAALVSISVSPTNSTVAK----------GLQENFKATGIFTDNSNSDITDQVTWDSS 356 Query: 263 NESIAKV-----DAGKITIEGTGKAVITASYLGVSKSVDIYV-RAPYEALLLNPEGDQTL 316 N I + G + G +TAS G+ S D V +A ++ ++P ++ Sbjct: 357 NTDILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFKVTQAALTSIEVSPT-RTSI 415 Query: 317 FLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTT 376 G + + + NS ++ + + W+S + + +VG T Sbjct: 416 AKGLTQKFTAIGIFTDNSKKDITDQVTWNSSSAI-----VSVSNLDNNKGLGKTNSVGNT 470 Query: 377 VIKGEYLGVSKSFKLTVLP-TLTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQ 435 I VS + TV+P LT + + L ++ TG D + +I+ Sbjct: 471 TITATLGKVSGNTWFTVVPAVLTSIQINPVNPSLAKGLTQKF-TATGIYSDNSNKDITSA 529 Query: 436 IEWTSADEEIVRIKDGKLVGGKA-GTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXX 494 + W S+D I I + + G A G T IK A+ + S Sbjct: 530 VTWFSSDSSIATISNAQKNQGNAYGAATGATDIK-----ATFGKVSSPVSTLSVTAAKLV 584 Query: 495 XXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMK 554 I P S G + +N + D+T + W S ++ + K Sbjct: 585 EIQITPA-AASKAKGLTERFKATGIFTDNSNS-DITNQVTWNSSNTDILTVSNTNAKRGL 642 Query: 555 GLSKGSATLKGTYSNKTI--SIPVTIEQK-VVKLLVEPSVLEMNIKASKSIKVTGTFSNG 611 G + T+K T S I S+ T+ Q + + V P+ + ++ TG F++ Sbjct: 643 GSTLKQGTVKVTASMGGIEDSVDFTVTQATLTSIEVSPTRASIAKGMTQKFTATGIFTDH 702 Query: 612 RTANFSGAMNWESSNTAVATVR-----GTSVKAVDEGTATLTGSYQGITATVKITVVPK- 665 N + + W+SS+ A++ + GT KA+ G T+T + + ++ ITV P Sbjct: 703 SKKNITEQVTWKSSSKALSMLNAPGEEGTG-KAIAVGKTTITATLEKLSGKTDITVTPAV 761 Query: 666 LTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISAS----GI 721 LT + +S + L G ++ T +Y + +T S W SS SVA IS + G Sbjct: 762 LTSIQISPVKHSLVKGLTEKFSATGIYSDNSNKDITSSVTWHSSNNSVATISNTKGYQGQ 821 Query: 722 ITAVGKGTTSIKGKYNN 738 G GT +IK N Sbjct: 822 AYGTGTGTVNIKATLGN 838 Score = 72.0 bits (175), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 168/719 (23%), Positives = 294/719 (40%), Gaps = 86/719 (11%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATY---NNAIATLEVSV 116 +S +DIT+A W SS++++ ++N G TG I AT+ ++ ++TL V+ Sbjct: 521 NSNKDITSAVTWFSSDSSIATISNAQKNQGNAYGAATGATDIKATFGKVSSPVSTLSVTA 580 Query: 117 THPFKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTI 176 E+ + ++ K L + K G + S D++ W SSN ++LT+ Sbjct: 581 AK-LVEIQITPAAASKAK------GLTERFKATGIFTDNSNSDITNQVTWNSSNTDILTV 633 Query: 177 EDGKITLVGEGKSTITAKYKGLTATFK-AVVQLPYSAIVLKDKAKDTAVKEMELLVGDSP 235 + T +GL +T K V++ S ++D T + + SP Sbjct: 634 SN-------------TNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQATLTSIEVSP 680 Query: 236 VQLSAMTKATE---------SSPEKDIAADANWTTSNESIAKVDA-GKITIEGTGKAV-- 283 + S T+ +K+I W +S+++++ ++A G+ EGTGKA+ Sbjct: 681 TRASIAKGMTQKFTATGIFTDHSKKNITEQVTWKSSSKALSMLNAPGE---EGTGKAIAV 737 Query: 284 ----ITASYLGVSKSVDIYVR-APYEALLLNPEGDQTLFLG--ESLRVKSFVRDAVNSSQ 336 ITA+ +S DI V A ++ ++P +L G E D NS++ Sbjct: 738 GKTTITATLEKLSGKTDITVTPAVLTSIQISPV-KHSLVKGLTEKFSATGIYSD--NSNK 794 Query: 337 NQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSF-KLTVLP 395 + + W S N GT IK VS KL+V Sbjct: 795 DITSSVTWHSSNN----SVATISNTKGYQGQAYGTGTGTVNIKATLGNVSSQVSKLSVTA 850 Query: 396 T-LTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLV 454 LTE+ + T +E+ K TG D + +I+DQ+ W S++ +I + Sbjct: 851 AELTEIVLNPTSSHKAKGLTENF-KATGVFTDNSTKDITDQVTWKSSNAAYAKISNAT-- 907 Query: 455 GGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPL 514 G G V K S ++A+ +I S + + P + L+ G P Sbjct: 908 -GSKGVVNALSK-GTSHISATLGSISSANATFQVTPARIASIEVTPNNF-FLIKGLSHPF 964 Query: 515 PGVKAVLENGDELDVTPTIKWEFSGSN-AVVKQT-----AAGKTMKGLSKGSATLKGTYS 568 + +N + D+T + W S N A + T +A G + +ATL + S Sbjct: 965 KAIGIYTDN-TKTDITKQVSWSSSDPNVASIDNTFSLAGSATAIDDGKTNITATLSDSMS 1023 Query: 569 NKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESS--- 625 T ++ VT ++ + V+PS+ ++ + + TG +S+ T + + + W SS Sbjct: 1024 AST-TLYVT-SAVLIDIEVKPSIFVLSEGLTLQLTATGIYSDHSTHDLTQVVQWTSSKPS 1081 Query: 626 NTAVATVRGTS--VKAVDEGTATLTGSYQGITATVKITVV--PKLTKLTVSETRLKLAPG 681 N A+ G V A+ G + T +Y I + V KL +T+S +++ G Sbjct: 1082 NIAIENTAGKKGKVTALAFGDSEFTATYDSIKSNRAWIFVNDEKLVNITISSSQVLTDKG 1141 Query: 682 ASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISAS----GIITAVGKGTTSIKGKY 736 ++Q + G+ +T W SS V IS S G+ TA+ G++ I Y Sbjct: 1142 SAQQFKAIGTFQGGSQLDLTDLVTWKSSDSKVVSISNSNDDRGLTTALSVGSSKISAIY 1200 Score = 71.2 bits (173), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 162/723 (22%), Positives = 306/723 (42%), Gaps = 70/723 (9%) Query: 45 ELTVGQTPKQLKVYASLEGSSSKRDITAAAIWTSSNTNVVKVAN-GLLTAVNTGTAMITA 103 +L + KQ + +S RDI+++ IW SSN+ + + N G+L +TG ++A Sbjct: 236 DLNIPLGKKQKLTATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSA 295 Query: 104 TYNNAIATLEVSVTHPFKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSAD 163 + N I ++++ VT P +++ S + + LQ K G + S D++ Sbjct: 296 SSENIIGSVKLIVT-PAALVSISVSPTNSTV----AKGLQENFKATGIFTDNSNSDITDQ 350 Query: 164 ADWTSSNPNVLTIED-----GKITLVGEGKSTITAKYKGLTAT--FKAVVQLPYSAIVLK 216 W SSN ++L+I + G + + +G +TA G+ + FK V Q ++I + Sbjct: 351 VTWDSSNTDILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFK-VTQAALTSIEVS 409 Query: 217 DKAKDTAVKEMELLVGDSPVQLSAMTKATESSPEKDIAADANWTTSNE--SIAKVDAGKI 274 A + + +A+ T++S +KDI W +S+ S++ +D K Sbjct: 410 PTRTSIAKGLTQ--------KFTAIGIFTDNS-KKDITDQVTWNSSSAIVSVSNLDNNKG 460 Query: 275 T--IEGTGKAVITASYLGVSKSVDI-YVRAPYEALLLNPEGDQTLFLGESLRVKSFVRDA 331 G ITA+ VS + V A ++ +NP + +L G + + + + Sbjct: 461 LGKTNSVGNTTITATLGKVSGNTWFTVVPAVLTSIQINPV-NPSLAKGLTQKFTATGIYS 519 Query: 332 VNSSQNQSVRTVW-SSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFK 390 NS+++ + W SSD+ + A G T IK + VS Sbjct: 520 DNSNKDITSAVTWFSSDSSIATISNAQKNQGNAYGA-----ATGATDIKATFGKVSSP-- 572 Query: 391 LTVLPTLTELTADKTEQELFTADSESLP------KVTGTKYDGTKLEISDQIEWTSADEE 444 + TL+ A E ++ A + K TG D + +I++Q+ W S++ + Sbjct: 573 ---VSTLSVTAAKLVEIQITPAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTD 629 Query: 445 IVRIKDGKLVGGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQ 504 I+ + + G T+ G +K V AS I S + P Sbjct: 630 ILTVSNTNAKRGLGSTLK-QGTVK---VTASMGGIE-DSVDFTVTQATLTSIEVSPTRA- 683 Query: 505 SLVIGEEKPLPGVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGK--TMKGLSKGSAT 562 S+ G + + + + ++T + W+ S S A+ A G+ T K ++ G T Sbjct: 684 SIAKGMTQKFTAT-GIFTDHSKKNITEQVTWK-SSSKALSMLNAPGEEGTGKAIAVGKTT 741 Query: 563 LKGTYSNKTISIPVTIEQKVV-KLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMN 621 + T + +T+ V+ + + P + ++ TG +S+ + + ++ Sbjct: 742 ITATLEKLSGKTDITVTPAVLTSIQISPVKHSLVKGLTEKFSATGIYSDNSNKDITSSVT 801 Query: 622 WESSNTAVATV---RGTSVKAVDEGTATLT-----GSYQGITATVKITVVPKLTKLTVSE 673 W SSN +VAT+ +G +A GT T+ G+ + + +T +LT++ ++ Sbjct: 802 WHSSNNSVATISNTKGYQGQAYGTGTGTVNIKATLGNVSSQVSKLSVTAA-ELTEIVLNP 860 Query: 674 TRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKIS----ASGIITAVGKGT 729 T A G ++ T ++ +T +T W SS + AKIS + G++ A+ KGT Sbjct: 861 TSSHKAKGLTENFKATGVFTDNSTKDITDQVTWKSSNAAYAKISNATGSKGVVNALSKGT 920 Query: 730 TSI 732 + I Sbjct: 921 SHI 923 Score = 57.8 bits (138), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 147/649 (22%), Positives = 259/649 (39%), Gaps = 91/649 (14%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHP 119 +S DIT W SSNT+++ V+N GL + + GT +TA+ +++ +VT Sbjct: 612 NSNSDITNQVTWNSSNTDILTVSNTNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQA 671 Query: 120 FK---ELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTI 176 E++ R+S + + K G + S K+++ W SS+ + + Sbjct: 672 TLTSIEVSPTRASIA--------KGMTQKFTATGIFTDHSKKNITEQVTWKSSSKALSML 723 Query: 177 ----EDGKITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVG 232 E+G + GK+TITA + L+ V + K + VK + Sbjct: 724 NAPGEEGTGKAIAVGKTTITATLEKLSGKTDITVTPAVLTSIQISPVKHSLVKGLT---- 779 Query: 233 DSPVQLSAMTKATESSPEKDIAADANWTTSNESIAKVD-----AGKITIEGTGKAVITAS 287 + SA +++S KDI + W +SN S+A + G+ GTG I A+ Sbjct: 780 ---EKFSATGIYSDNS-NKDITSSVTWHSSNNSVATISNTKGYQGQAYGTGTGTVNIKAT 835 Query: 288 YLGVSKSVDIY--VRAPYEALLLNP-EGDQTLFLGESLRVKSFVRDAVNSSQNQSVRTVW 344 VS V A ++LNP + L E+ + D NS+++ + + W Sbjct: 836 LGNVSSQVSKLSVTAAELTEIVLNPTSSHKAKGLTENFKATGVFTD--NSTKDITDQVTW 893 Query: 345 SSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKG-----EYLGVSKSFKLTVLPTLTE 399 S N K V + KG LG S T T Sbjct: 894 KSSN----------AAYAKISNATGSKGVVNALSKGTSHISATLGSISSANATFQVTPAR 943 Query: 400 LTA-DKTEQELFTADSESLP-KVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVGGK 457 + + + T F S P K G D TK +I+ Q+ W+S+D + I + + G Sbjct: 944 IASIEVTPNNFFLIKGLSHPFKAIGIYTDNTKTDITKQVSWSSSDPNVASIDNTFSLAGS 1003 Query: 458 A-----GTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPE-DPQSLVIGEE 511 A G +T + +S A++ + S I E P V+ E Sbjct: 1004 ATAIDDGKTNITATLSDSMSASTTLYVTS-------------AVLIDIEVKPSIFVLSEG 1050 Query: 512 KPLP-GVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMK--GLSKGSATLKGTY- 567 L + + D+T ++W S + + + AGK K L+ G + TY Sbjct: 1051 LTLQLTATGIYSDHSTHDLTQVVQWTSSKPSNIAIENTAGKKGKVTALAFGDSEFTATYD 1110 Query: 568 ---SNKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWES 624 SN+ I V ++K+V + + S + + +++ K GTF G + + + W+S Sbjct: 1111 SIKSNRAW-IFVN-DEKLVNITISSSQVLTDKGSAQQFKAIGTFQGGSQLDLTDLVTWKS 1168 Query: 625 SNTAVATV------RGTSVKAVDEGTATLTGSYQGITA-TVKITVVPKL 666 S++ V ++ RG + A+ G++ ++ Y I + ++ V P++ Sbjct: 1169 SDSKVVSISNSNDDRGLTT-ALSVGSSKISAIYGSIHSDSIDFEVTPEI 1216 Score = 55.8 bits (133), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 105/230 (45%), Gaps = 13/230 (5%) Query: 517 VKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMKGLSKGSATLK----GTYSNKTI 572 V A+ +NG ++T + S +VV T G ++G++ GS+ +K G YS + I Sbjct: 75 VTAIFDNGTNQNITDSTSI-VPDSQSVV--TIEGNRVRGIASGSSIIKAEYNGLYSEQKI 131 Query: 573 SIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGA--MNWESSNTAVA 630 ++ I + +E +L ++ G FS+G + S + W SSN + Sbjct: 132 TVTPAILNSIQVTSLESGILPKG--TNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLV 189 Query: 631 TVRGTSVKA-VDEGTATLTGSYQGITATVKITVVPK-LTKLTVSETRLKLAPGASQGVVV 688 V + + + ++ GTA + S+Q ++TV L+++ V+ L + G Q + Sbjct: 190 RVDDSGLASGINLGTAHIRASFQSKQGAEEMTVGDAVLSQIQVTSNDLNIPLGKKQKLTA 249 Query: 689 TALYDTGNTATVTGSTVWTSSKPSVAKISASGIITAVGKGTTSIKGKYNN 738 T +Y + ++ S +W SS ++A I +GI+ G ++ N Sbjct: 250 TGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASSEN 299 Score = 55.1 bits (131), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 35/145 (24%), Positives = 71/145 (48%), Gaps = 4/145 (2%) Query: 599 SKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVKAVDEGTATLTGSYQGITATV 658 S +++VT F NG N + + + + +V T+ G V+ + G++ + Y G+ + Sbjct: 70 STTLEVTAIFDNGTNQNITDSTSIVPDSQSVVTIEGNRVRGIASGSSIIKAEYNGLYSEQ 129 Query: 659 KITVVPK-LTKLTVSETRLKLAP-GASQGVVVTALYDTGNTATVTGS--TVWTSSKPSVA 714 KITV P L + V+ + P G ++ ++ G+ ++ VW+SS P + Sbjct: 130 KITVTPAILNSIQVTSLESGILPKGTNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLV 189 Query: 715 KISASGIITAVGKGTTSIKGKYNNK 739 ++ SG+ + + GT I+ + +K Sbjct: 190 RVDDSGLASGINLGTAHIRASFQSK 214 >dbj|BAD06007.1| bacterial immunogloblin [Leptospira interrogans serovar manilae] Length = 1224 Score = 79.0 bits (193), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 177/741 (23%), Positives = 295/741 (39%), Gaps = 75/741 (10%) Query: 33 LNSIEFDSSAKVELTVGQTPKQLKVYASLEG---SSSKRDITAAA--IWTSSNTNVVKVA 87 LNSI+ S L G PK S G S +DI+ +W+SSN ++V+V Sbjct: 138 LNSIQVTS-----LESGILPKGTNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLVQVD 192 Query: 88 N-GLLTAVNTGTAMITATYNNAIATLEVSVTHPFKELTLERSSDGNYKLGDSEESLQVKA 146 + GL + +N GTA I A++ + E++V S++ N LG + K Sbjct: 193 DSGLASGINLGTAHIRASFQSKQGAEEMTVGDAILSQIQVTSNNLNIPLGKKQ-----KL 247 Query: 147 KVVGGESATSVKDVSADADWTSSNPNVLTIEDGKITLVGE-GKSTITAKYKGLTATFKAV 205 G S S +D+S+ W SSN + I++ I + G T++A + + + K + Sbjct: 248 TATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASSENIIGSVKLI 307 Query: 206 VQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAMTKAT---ESSPEKDIAADANWTTS 262 V P + + + ++AV + L KAT + DI W +S Sbjct: 308 VT-PAALVSISVSPTNSAVAK----------GLQENFKATGIFTDNSNSDITDQVTWDSS 356 Query: 263 NESIAKV-----DAGKITIEGTGKAVITASYLGVSKSVDIYV-RAPYEALLLNPEGDQTL 316 N+ I + G + G +TAS G+ S D V +A ++ ++P ++ Sbjct: 357 NKDILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFTVTQAALTSIEVSPT-RTSI 415 Query: 317 FLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTT 376 G + + + NS ++ + + W+S + + AVG T Sbjct: 416 AKGLTQKFTAIGIFTDNSKKDITDQVTWNSSSAI-----ASVSNLDDNKGLGKAHAVGDT 470 Query: 377 VIKGEYLGVSKSFKLTVLPT-LTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQ 435 I VS TV+P LT + + L ++ TG D + +IS Sbjct: 471 TITATLGKVSGKTWFTVVPAVLTSIQINPVNPSLAKGLTQKF-TATGIYSDNSNKDISSS 529 Query: 436 IEWTSADEEIVRIKDGKLVGGKA-GTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXX 494 + W S+D I I + K G A G T IK A+ + S Sbjct: 530 VTWFSSDSSIATISNAKKNQGNAYGAATGATDIK-----ATFGKVSSPVSTLSVTAAKLV 584 Query: 495 XXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIKWEFSGSNAV-VKQTAA---- 549 I P S G + +N + D+T + W S +N + V T A Sbjct: 585 EIQITPA-AASKAKGLTERFKATGIFTDNSNS-DITNQVTWNSSNTNILSVSNTNAKRGL 642 Query: 550 GKTMK-GLSKGSATLKGTYSNKTISIPVTIEQK-VVKLLVEPSVLEMNIKASKSIKVTGT 607 G T+K G K +A++ G S+ T+ Q + + V P+ + ++ TG Sbjct: 643 GSTLKQGTVKVTASMGGIED----SVDFTVTQATLTSIEVSPTRASIAKGMTQKFTATGI 698 Query: 608 FSNGRTANFSGAMNWESSNTAVATV-----RGTSVKAVDEGTATLTGSYQGITATVKITV 662 F++ + + + W+SS+ A+ + GT KA+ G T+T + + ++ ITV Sbjct: 699 FTDHSKKDITEQVTWKSSSKALNMLNAPGEEGTG-KAIAVGKTTITATLEKLSGKTDITV 757 Query: 663 VPK-LTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISAS-- 719 P LT + +S + L G ++ T +Y + +T S W SS S+A IS + Sbjct: 758 TPAVLTSIQISPVKHSLVKGLTEKFSATGIYSDNSNKDITSSVTWHSSNNSIATISNTKN 817 Query: 720 --GIITAVGKGTTSIKGKYNN 738 G G G IK N Sbjct: 818 YQGQAYGTGTGKVDIKATLGN 838 Score = 76.3 bits (186), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 154/695 (22%), Positives = 293/695 (42%), Gaps = 90/695 (12%) Query: 66 SKRDITAAAIWTSSNTNVVKVANGLLTAVNTGTAMITATYNNAIATLEVSVTHPFKELTL 125 + ++IT + S + +VV + + + +G+++I A YN + +++VT P ++ Sbjct: 83 TNQNITDSTSIVSDSQSVVTIEGNRVRGIASGSSIIKAEYNGLYSEQKITVT-PAILNSI 141 Query: 126 ERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADA--DWTSSNPNVLTIED-GKIT 182 + +S + G + + +G S S +D+S + W+SSNP+++ ++D G + Sbjct: 142 QVTS---LESGILPKGTNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLVQVDDSGLAS 198 Query: 183 LVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAMT 242 + G + I A ++ + V D + ++++ + + L Sbjct: 199 GINLGTAHIRASFQSKQGAEEMTV-------------GDAILSQIQVTSNNLNIPLGKKQ 245 Query: 243 KATES-----SPEKDIAADANWTTSNESIAKV-DAGKITIEGTGKAVITASYLGVSKSVD 296 K T + + +DI++ W +SN +IA + + G + TG ++AS + SV Sbjct: 246 KLTATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASSENIIGSVK 305 Query: 297 IYVR-APYEALLLNPEGDQTL-FLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXX 354 + V A ++ ++P L E+ + D NS+ + + + W S N+ Sbjct: 306 LIVTPAALVSISVSPTNSAVAKGLQENFKATGIFTD--NSNSDITDQVTWDSSNKDILSI 363 Query: 355 XXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFKLT--------VLPTLTELTADKTE 406 T I G + S F +T V PT T + T+ Sbjct: 364 SNASDSHGLASTLNQGNVKVTASIGG--IQGSTDFTVTQAALTSIEVSPTRTSIAKGLTQ 421 Query: 407 QELFTADSESLPKVTGTKYDGTKLEISDQIEW--TSADEEIVRIKDGKLVG--GKAGTVT 462 + FTA G D +K +I+DQ+ W +SA + + D K +G G T Sbjct: 422 K--FTA--------IGIFTDNSKKDITDQVTWNSSSAIASVSNLDDNKGLGKAHAVGDTT 471 Query: 463 LT---GKIKNST-VAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPGVK 518 +T GK+ T P+ + S I P +P SL G + Sbjct: 472 ITATLGKVSGKTWFTVVPAVLTS--------------IQINPVNP-SLAKGLTQKFTATG 516 Query: 519 AVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTM---KGLSKGSATLKGTYSNKTISIP 575 +N ++ D++ ++ W FS +++ + A K G + G+ +K T+ +S P Sbjct: 517 IYSDNSNK-DISSSVTW-FSSDSSIATISNAKKNQGNAYGAATGATDIKATFGK--VSSP 572 Query: 576 VTI----EQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVAT 631 V+ K+V++ + P+ ++ K TG F++ ++ + + W SSNT + + Sbjct: 573 VSTLSVTAAKLVEIQITPAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTNILS 632 Query: 632 VRGTSVK-----AVDEGTATLTGSYQGITATVKITVVPK-LTKLTVSETRLKLAPGASQG 685 V T+ K + +GT +T S GI +V TV LT + VS TR +A G +Q Sbjct: 633 VSNTNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQATLTSIEVSPTRASIAKGMTQK 692 Query: 686 VVVTALYDTGNTATVTGSTVWTSSKPSVAKISASG 720 T ++ + +T W SS ++ ++A G Sbjct: 693 FTATGIFTDHSKKDITEQVTWKSSSKALNMLNAPG 727 Score = 72.0 bits (175), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 166/708 (23%), Positives = 305/708 (43%), Gaps = 80/708 (11%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-GLLTAVNTGTAMITATYNNAIATLEVSVTHPFKEL 123 +S RDI+++ IW SSN+ + + N G+L +TG ++A+ N I ++++ VT P + Sbjct: 256 NSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASSENIIGSVKLIVT-PAALV 314 Query: 124 TLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTIED----- 178 ++ S + + LQ K G + S D++ W SSN ++L+I + Sbjct: 315 SISVSPTNSAV----AKGLQENFKATGIFTDNSNSDITDQVTWDSSNKDILSISNASDSH 370 Query: 179 GKITLVGEGKSTITAKYKGLT-ATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQ 237 G + + +G +TA G+ +T V Q ++I + A + + Sbjct: 371 GLASTLNQGNVKVTASIGGIQGSTDFTVTQAALTSIEVSPTRTSIAKGLTQ--------K 422 Query: 238 LSAMTKATESSPEKDIAADANWTTSNE--SIAKVDAGKITIEGTGKA------VITASYL 289 +A+ T++S +KDI W +S+ S++ +D K G GKA ITA+ Sbjct: 423 FTAIGIFTDNS-KKDITDQVTWNSSSAIASVSNLDDNK----GLGKAHAVGDTTITATLG 477 Query: 290 GVS-KSVDIYVRAPYEALLLNPEGDQTLFLGESLRVKSFVRDAVNSSQNQSVRTVW-SSD 347 VS K+ V A ++ +NP + +L G + + + + NS+++ S W SSD Sbjct: 478 KVSGKTWFTVVPAVLTSIQINPV-NPSLAKGLTQKFTATGIYSDNSNKDISSSVTWFSSD 536 Query: 348 NQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFKLTVLPTLTELTADKTEQ 407 + + A G T IK + VS + + TL+ A E Sbjct: 537 SSIATISNAKKNQGNAYGA-----ATGATDIKATFGKVS-----SPVSTLSVTAAKLVEI 586 Query: 408 ELFTADSESLP------KVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVGGKAGTV 461 ++ A + K TG D + +I++Q+ W S++ I+ + + G T+ Sbjct: 587 QITPAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTNILSVSNTNAKRGLGSTL 646 Query: 462 TLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPGVKAVL 521 G +K V AS I S + P S+ G + + Sbjct: 647 K-QGTVK---VTASMGGIE-DSVDFTVTQATLTSIEVSPTRA-SIAKGMTQKFTAT-GIF 699 Query: 522 ENGDELDVTPTIKWEFSGSNAVVKQTAAGK--TMKGLSKGSATLKGTYSNKTISIPVTIE 579 + + D+T + W+ S S A+ A G+ T K ++ G T+ T + +T+ Sbjct: 700 TDHSKKDITEQVTWK-SSSKALNMLNAPGEEGTGKAIAVGKTTITATLEKLSGKTDITVT 758 Query: 580 QKVV-KLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVK 638 V+ + + P + ++ TG +S+ + + ++ W SSN ++AT+ T Sbjct: 759 PAVLTSIQISPVKHSLVKGLTEKFSATGIYSDNSNKDITSSVTWHSSNNSIATISNTKNY 818 Query: 639 AVDEGTATLTGSYQ-GITATV--------KITV-VPKLTKLTVSETRLKLAPGASQGVVV 688 +G A TG+ + I AT+ K++V +LT++ ++ T A G ++ Sbjct: 819 ---QGQAYGTGTGKVDIKATLGNVSSPVSKLSVTAAELTEIVLNPTSSHKAKGLTENFKA 875 Query: 689 TALYDTGNTATVTGSTVWTSSKPSVAKIS----ASGIITAVGKGTTSI 732 T ++ +T +T W SS + AKIS + G++ A+ KGT+ I Sbjct: 876 TGVFTDNSTKDITDQVTWKSSNAAYAKISNATGSKGVVNALSKGTSHI 923 Score = 68.6 bits (166), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 166/719 (23%), Positives = 292/719 (40%), Gaps = 86/719 (11%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATY---NNAIATLEVSV 116 +S +DI+++ W SS++++ ++N G TG I AT+ ++ ++TL V+ Sbjct: 521 NSNKDISSSVTWFSSDSSIATISNAKKNQGNAYGAATGATDIKATFGKVSSPVSTLSVTA 580 Query: 117 THPFKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTI 176 E+ + ++ K L + K G + S D++ W SSN N+L++ Sbjct: 581 AK-LVEIQITPAAASKAK------GLTERFKATGIFTDNSNSDITNQVTWNSSNTNILSV 633 Query: 177 EDGKITLVGEGKSTITAKYKGLTATFK-AVVQLPYSAIVLKDKAKDTAVKEMELLVGDSP 235 + T +GL +T K V++ S ++D T + + SP Sbjct: 634 SN-------------TNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQATLTSIEVSP 680 Query: 236 VQLSAMTKATE---------SSPEKDIAADANWTTSNESIAKVDA-GKITIEGTGKAV-- 283 + S T+ +KDI W +S++++ ++A G+ EGTGKA+ Sbjct: 681 TRASIAKGMTQKFTATGIFTDHSKKDITEQVTWKSSSKALNMLNAPGE---EGTGKAIAV 737 Query: 284 ----ITASYLGVSKSVDIYVR-APYEALLLNPEGDQTLFLG--ESLRVKSFVRDAVNSSQ 336 ITA+ +S DI V A ++ ++P +L G E D NS++ Sbjct: 738 GKTTITATLEKLSGKTDITVTPAVLTSIQISPV-KHSLVKGLTEKFSATGIYSD--NSNK 794 Query: 337 NQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSF-KLTVLP 395 + + W S N G IK VS KL+V Sbjct: 795 DITSSVTWHSSNN----SIATISNTKNYQGQAYGTGTGKVDIKATLGNVSSPVSKLSVTA 850 Query: 396 T-LTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLV 454 LTE+ + T +E+ K TG D + +I+DQ+ W S++ +I + Sbjct: 851 AELTEIVLNPTSSHKAKGLTENF-KATGVFTDNSTKDITDQVTWKSSNAAYAKISNAT-- 907 Query: 455 GGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPL 514 G G V K S ++A+ +I S + + P + L+ G P Sbjct: 908 -GSKGVVNALSK-GTSHISATLGSISSANATFQVTPARIASIEVTPNN-FFLIKGLSHPF 964 Query: 515 PGVKAVLENGDELDVTPTIKWEFSGSN-AVVKQT-----AAGKTMKGLSKGSATLKGTYS 568 + +N + D+T + W S N A + T +A G + +ATL + S Sbjct: 965 KAIGIYTDN-TKTDITKQVSWSSSDPNVASIDNTFSLAGSATAIDDGKTNITATLSDSMS 1023 Query: 569 NKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESS--- 625 T ++ VT ++++ V+PS+ ++ + + TG +S+ T + + + W SS Sbjct: 1024 TST-TLYVT-SAALIEIEVKPSIFVLSEGLTLQLTATGIYSDYSTHDLTQVVQWTSSKPS 1081 Query: 626 NTAVATVRGTS--VKAVDEGTATLTGSYQGITATVKITVV--PKLTKLTVSETRLKLAPG 681 N A+ G V A+ G + T +Y I + V KL +T+S +++ G Sbjct: 1082 NIAIENTAGKKGKVTALAFGDSEFTATYDSIESNRAWIFVNDEKLVNITISSSQVLTDKG 1141 Query: 682 ASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISAS----GIITAVGKGTTSIKGKY 736 +Q + G+ +T W SS V IS S G+ TA+ G++ I Y Sbjct: 1142 PAQQFKAIGTFQGGSQLDLTDLVTWKSSDSKVVSISNSNDDRGLTTALSVGSSKISAIY 1200 Score = 63.5 bits (153), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 154/644 (23%), Positives = 257/644 (39%), Gaps = 81/644 (12%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHP 119 +S DIT W SSNTN++ V+N GL + + GT +TA+ +++ +VT Sbjct: 612 NSNSDITNQVTWNSSNTNILSVSNTNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQA 671 Query: 120 FK---ELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNP--NVL 174 E++ R+S + + K G + S KD++ W SS+ N+L Sbjct: 672 TLTSIEVSPTRASIA--------KGMTQKFTATGIFTDHSKKDITEQVTWKSSSKALNML 723 Query: 175 TI--EDGKITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVG 232 E+G + GK+TITA + L+ V + K + VK + Sbjct: 724 NAPGEEGTGKAIAVGKTTITATLEKLSGKTDITVTPAVLTSIQISPVKHSLVKGLT---- 779 Query: 233 DSPVQLSAMTKATESSPEKDIAADANWTTSNESIAKVD-----AGKITIEGTGKAVITAS 287 + SA +++S KDI + W +SN SIA + G+ GTGK I A+ Sbjct: 780 ---EKFSATGIYSDNS-NKDITSSVTWHSSNNSIATISNTKNYQGQAYGTGTGKVDIKAT 835 Query: 288 YLGVSKSVDIY--VRAPYEALLLNP-EGDQTLFLGESLRVKSFVRDAVNSSQNQSVRTVW 344 VS V A ++LNP + L E+ + D NS+++ + + W Sbjct: 836 LGNVSSPVSKLSVTAAELTEIVLNPTSSHKAKGLTENFKATGVFTD--NSTKDITDQVTW 893 Query: 345 SSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKG-----EYLGVSKSFKLTVLPTLTE 399 S N K V + KG LG S T T Sbjct: 894 KSSN----------AAYAKISNATGSKGVVNALSKGTSHISATLGSISSANATFQVTPAR 943 Query: 400 LTA-DKTEQELFTADSESLP-KVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVGGK 457 + + + T F S P K G D TK +I+ Q+ W+S+D + I + + G Sbjct: 944 IASIEVTPNNFFLIKGLSHPFKAIGIYTDNTKTDITKQVSWSSSDPNVASIDNTFSLAGS 1003 Query: 458 AGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPE-DPQSLVIGEEKPLP- 515 A T GK + +A S S I E P V+ E L Sbjct: 1004 A-TAIDDGK-------TNITATLSDSMSTSTTLYVTSAALIEIEVKPSIFVLSEGLTLQL 1055 Query: 516 GVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMK--GLSKGSATLKGTY----SN 569 + + D+T ++W S + + + AGK K L+ G + TY SN Sbjct: 1056 TATGIYSDYSTHDLTQVVQWTSSKPSNIAIENTAGKKGKVTALAFGDSEFTATYDSIESN 1115 Query: 570 KTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAV 629 + I V ++K+V + + S + + ++ K GTF G + + + W+SS++ V Sbjct: 1116 RAW-IFVN-DEKLVNITISSSQVLTDKGPAQQFKAIGTFQGGSQLDLTDLVTWKSSDSKV 1173 Query: 630 ATV------RGTSVKAVDEGTATLTGSYQGITA-TVKITVVPKL 666 ++ RG + A+ G++ ++ Y I + ++ V P++ Sbjct: 1174 VSISNSNDDRGLTT-ALSVGSSKISAIYGSIHSDSIDFEVTPEI 1216 Score = 58.5 bits (140), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 56/230 (24%), Positives = 106/230 (46%), Gaps = 13/230 (5%) Query: 517 VKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMKGLSKGSATLK----GTYSNKTI 572 V A+ +NG ++T + S S +VV T G ++G++ GS+ +K G YS + I Sbjct: 75 VTAIFDNGTNQNITDSTSI-VSDSQSVV--TIEGNRVRGIASGSSIIKAEYNGLYSEQKI 131 Query: 573 SIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGA--MNWESSNTAVA 630 ++ I + +E +L ++ G FS+G + S + W SSN + Sbjct: 132 TVTPAILNSIQVTSLESGILPKG--TNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLV 189 Query: 631 TVRGTSVKA-VDEGTATLTGSYQGITATVKITVVPK-LTKLTVSETRLKLAPGASQGVVV 688 V + + + ++ GTA + S+Q ++TV L+++ V+ L + G Q + Sbjct: 190 QVDDSGLASGINLGTAHIRASFQSKQGAEEMTVGDAILSQIQVTSNNLNIPLGKKQKLTA 249 Query: 689 TALYDTGNTATVTGSTVWTSSKPSVAKISASGIITAVGKGTTSIKGKYNN 738 T +Y + ++ S +W SS ++A I +GI+ G ++ N Sbjct: 250 TGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASSEN 299 Score = 57.0 bits (136), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 72/145 (49%), Gaps = 4/145 (2%) Query: 599 SKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVKAVDEGTATLTGSYQGITATV 658 S +++VT F NG N + + + S + +V T+ G V+ + G++ + Y G+ + Sbjct: 70 STTLEVTAIFDNGTNQNITDSTSIVSDSQSVVTIEGNRVRGIASGSSIIKAEYNGLYSEQ 129 Query: 659 KITVVPK-LTKLTVSETRLKLAP-GASQGVVVTALYDTGNTATVTGS--TVWTSSKPSVA 714 KITV P L + V+ + P G ++ ++ G+ ++ VW+SS P + Sbjct: 130 KITVTPAILNSIQVTSLESGILPKGTNRQFSAIGIFSDGSHQDISNEPLIVWSSSNPDLV 189 Query: 715 KISASGIITAVGKGTTSIKGKYNNK 739 ++ SG+ + + GT I+ + +K Sbjct: 190 QVDDSGLASGINLGTAHIRASFQSK 214 Score = 56.2 bits (134), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 176/718 (24%), Positives = 281/718 (39%), Gaps = 84/718 (11%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHP 119 +SK+DIT W SS+ + V+N GL A G ITAT +V Sbjct: 432 NSKKDITDQVTWNSSSA-IASVSNLDDNKGLGKAHAVGDTTITATLGKVSGKTWFTVVPA 490 Query: 120 FKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTIEDG 179 LT + + N L + L K G S S KD+S+ W SS+ ++ TI + Sbjct: 491 V--LTSIQINPVNPSLA---KGLTQKFTATGIYSDNSNKDISSSVTWFSSDSSIATISNA 545 Query: 180 KITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLS 239 K G T + ATF V P S + + TA K +E+ + +P S Sbjct: 546 KKNQ-GNAYGAATGATD-IKATFGKVSS-PVSTLSV------TAAKLVEIQI--TPAAAS 594 Query: 240 AMTKATE---------SSPEKDIAADANWTTSNESI-------AKVDAGKITIEGTGKAV 283 TE + DI W +SN +I AK G +GT K Sbjct: 595 KAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTNILSVSNTNAKRGLGSTLKQGTVK-- 652 Query: 284 ITASYLGVSKSVDIYV-RAPYEALLLNPEGDQTLFLGESLRVKSFVRDAVNSSQNQSVRT 342 +TAS G+ SVD V +A ++ ++P ++ G + + + +S ++ + + Sbjct: 653 VTASMGGIEDSVDFTVTQATLTSIEVSPT-RASIAKGMTQKFTATGIFTDHSKKDITEQV 711 Query: 343 VWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFKLTVLPT-LTELT 401 W S ++ AVG T I +S +TV P LT + Sbjct: 712 TWKSSSKALNMLNAPGEEGTGKAI-----AVGKTTITATLEKLSGKTDITVTPAVLTSIQ 766 Query: 402 ADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVGGKAGTV 461 + L +E TG D + +I+ + W S++ I I + K G+A Sbjct: 767 ISPVKHSLVKGLTEKF-SATGIYSDNSNKDITSSVTWHSSNNSIATISNTKNYQGQA-YG 824 Query: 462 TLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPL-PGVKA- 519 T TGK+ + A+ + S + P + K L KA Sbjct: 825 TGTGKVD---IKATLGNVSSPVSKLSVTAAELTEIVLNPTSSH-----KAKGLTENFKAT 876 Query: 520 -VLENGDELDVTPTIKWEFSG------SNAVVKQTAAGKTMKGLSKGSATLKGTYSNKTI 572 V + D+T + W+ S SNA + KG S SATL G+ S+ Sbjct: 877 GVFTDNSTKDITDQVTWKSSNAAYAKISNATGSKGVVNALSKGTSHISATL-GSISSANA 935 Query: 573 SIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVATV 632 + VT ++ + V P+ + S K G +++ + + ++W SS+ VA++ Sbjct: 936 TFQVT-PARIASIEVTPNNFFLIKGLSHPFKAIGIYTDNTKTDITKQVSWSSSDPNVASI 994 Query: 633 RGT-----SVKAVDEG----TATLTGSYQGITATVKITVVPKLTKLTVSETRLKLAPGAS 683 T S A+D+G TATL+ S T+T L ++ V + L+ G + Sbjct: 995 DNTFSLAGSATAIDDGKTNITATLSDSMS--TSTTLYVTSAALIEIEVKPSIFVLSEGLT 1052 Query: 684 QGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISAS----GIITAVGKGTTSIKGKYN 737 + T +Y +T +T WTSSKPS I + G +TA+ G + Y+ Sbjct: 1053 LQLTATGIYSDYSTHDLTQVVQWTSSKPSNIAIENTAGKKGKVTALAFGDSEFTATYD 1110 >gb|AAN52495.1| putative surface protein [Leptospira interrogans serovar pomona] Length = 1225 Score = 78.6 bits (192), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 152/678 (22%), Positives = 278/678 (41%), Gaps = 90/678 (13%) Query: 83 VVKVANGLLTAVNTGTAMITATYNNAIATLEVSVTHPFKELTLERSSDGNYKLGDSEESL 142 VV + + + +G+++I A YN + +++VT TL + + G + Sbjct: 100 VVTIQGNRVRGIASGSSIIKAEYNGLYSEQKITVT----PATLNSIQVTSLESGILPKGT 155 Query: 143 QVKAKVVGGESATSVKDVSADA--DWTSSNPNVLTIED-GKITLVGEGKSTITAKYKGLT 199 + +G S S +D+S D W+SSNP+++ ++D G + + G + I A ++ Sbjct: 156 NRQFSAIGIFSDGSHQDISNDPLIVWSSSNPDLVQVDDSGLASGINLGTAHIRASFQSKQ 215 Query: 200 ATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAMTKATES-----SPEKDIA 254 + V D + ++++ + + L K + + +DI+ Sbjct: 216 GAEEMTV-------------GDAVLSQIQVTSNNPNIPLGKKQKLIATGIYSDNSNRDIS 262 Query: 255 ADANWTTSNESIAKV-DAGKITIEGTGKAVITASYLGVSKSVDIYVR-APYEALLLNPEG 312 + W +SN +IA + + G + TG I+AS + SV + V A ++ ++P Sbjct: 263 SSVIWNSSNSTIANIQNNGILETADTGIVTISASSENIIGSVKLIVTPAALVSISVSPTN 322 Query: 313 DQTL-FLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXK 371 L E+ + D NS+ + + + W S N Sbjct: 323 STVAKGLQENFKATGIFTD--NSNSDITDQVTWDSSNTDILSISNASDSHGLASTLNQGN 380 Query: 372 AVGTTVIKGEYLGVSKSFKLT--------VLPTLTELTADKTEQELFTADSESLPKVTGT 423 T I G + S F +T V P L + T++ FTA G Sbjct: 381 VKVTASIGG--IQGSTDFTVTQAALTSIEVSPVLPSIAKGLTQK--FTA--------IGI 428 Query: 424 KYDGTKLEISDQIEWTSADE--EIVRIKDGKLVG--GKAGTVTLT---GKIKNST-VAAS 475 D +K +I+DQ+ W S+ + + D K +G G T+T GK+ T + Sbjct: 429 FTDNSKKDITDQVTWNSSSAIVSVSNLDDNKGLGKAHAVGDTTITATLGKVSGKTWLTVV 488 Query: 476 PSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPGVKAVLENGDELDVTPTIKW 535 P+ + S I P +P SL G + +N ++ D+T + W Sbjct: 489 PAVLTS--------------IQINPVNP-SLAKGLTQKFSATGIYSDNSNK-DITSAVTW 532 Query: 536 EFSGSNAVVKQTAAGKTM---KGLSKGSATLKGTYSNKTISIPVTI----EQKVVKLLVE 588 FS +++ + A K G + G+ +K T+ +S PV+ K+V++ + Sbjct: 533 -FSSDSSIATISNAQKNQGNAYGAATGATDIKATFGK--VSSPVSTLSVTAAKLVEIQIT 589 Query: 589 PSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVK-----AVDEG 643 P+ ++ K TG F++ ++ + + W SSNT + TV T+ K + +G Sbjct: 590 PAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTDILTVSNTNAKRGLGSTLKQG 649 Query: 644 TATLTGSYQGITATVKITVVPK-LTKLTVSETRLKLAPGASQGVVVTALYDTGNTATVTG 702 T +T S GI +V TV LT + VS TR +A G +Q T ++ + +T Sbjct: 650 TVKVTASMGGIEDSVDFTVTQATLTSIEVSPTRASIAKGMTQKFTATGIFTDHSKKNITE 709 Query: 703 STVWTSSKPSVAKISASG 720 W SS +++ ++A G Sbjct: 710 QVTWKSSSKALSMLNAPG 727 Score = 68.2 bits (165), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 173/729 (23%), Positives = 307/729 (42%), Gaps = 97/729 (13%) Query: 53 KQLKVYASLEGSSSKRDITAAAIWTSSNTNVVKVAN-GLLTAVNTGTAMITATYNNAIAT 111 KQ + + +S RDI+++ IW SSN+ + + N G+L +TG I+A+ N I + Sbjct: 244 KQKLIATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTISASSENIIGS 303 Query: 112 LEVSVTHPFKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNP 171 +++ VT P +++ S + + LQ K G + S D++ W SSN Sbjct: 304 VKLIVT-PAALVSISVSPTNSTV----AKGLQENFKATGIFTDNSNSDITDQVTWDSSNT 358 Query: 172 NVLTIED-----GKITLVGEGKSTITAKYKGLT-ATFKAVVQLPYSAI----VLKDKAKD 221 ++L+I + G + + +G +TA G+ +T V Q ++I VL AK Sbjct: 359 DILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFTVTQAALTSIEVSPVLPSIAKG 418 Query: 222 TAVKEMELLVGDSPVQLSAMTKATESSPEKDIAADANWTTSNE--SIAKVDAGKITIEGT 279 K +A+ T++S +KDI W +S+ S++ +D K G Sbjct: 419 LTQK------------FTAIGIFTDNS-KKDITDQVTWNSSSAIVSVSNLDDNK----GL 461 Query: 280 GKA------VITASYLGVS-KSVDIYVRAPYEALLLNPEGDQTLFLGESLRVKSFVRDAV 332 GKA ITA+ VS K+ V A ++ +NP + +L G + + + + Sbjct: 462 GKAHAVGDTTITATLGKVSGKTWLTVVPAVLTSIQINPV-NPSLAKGLTQKFSATGIYSD 520 Query: 333 NSSQNQSVRTVW-SSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFKL 391 NS+++ + W SSD+ + A G T IK + VS Sbjct: 521 NSNKDITSAVTWFSSDSSIATISNAQKNQGNAYGA-----ATGATDIKATFGKVS----- 570 Query: 392 TVLPTLTELTADKTEQELFTADSESLP------KVTGTKYDGTKLEISDQIEWTSADEEI 445 + + TL+ A E ++ A + K TG D + +I++Q+ W S++ +I Sbjct: 571 SPVSTLSVTAAKLVEIQITPAAASKAKGLTERFKATGIFTDNSNSDITNQVTWNSSNTDI 630 Query: 446 VRIKDGKLVGGKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQS 505 + + + G G+ G +K V AS I S + P S Sbjct: 631 LTVSNTNAKRG-LGSTLKQGTVK---VTASMGGIE-DSVDFTVTQATLTSIEVSPTRA-S 684 Query: 506 LVIGEEKPLPGVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMKGLSKGSATLKG 565 + G + + + + ++T + W+ S S A+ A G+ +G K A K Sbjct: 685 IAKGMTQKFTAT-GIFTDHSKKNITEQVTWK-SSSKALSMLNAPGE--EGTGKAIAVGKH 740 Query: 566 TYSNKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSI----------KVTGTFSNGRTAN 615 Y ++ T + S N ++ K+I TG +S+ + + Sbjct: 741 YY---YCNLRKTFRENRYYRYSRNSYFNSN-QSCKNIVLVKGLTEKFSATGIYSDNSSKD 796 Query: 616 FSGAMNWESSNTAVATV---RGTSVKAVDEGTATLT-----GSYQGITATVKITVVPKLT 667 + A+ W SSN +VAT+ +G +A GT T+ G+ + + +T +L Sbjct: 797 ITSAVTWHSSNNSVATISNTKGYQGQAHGTGTGTVDIKATLGNVSSQVSRLSVTAA-ELI 855 Query: 668 KLTVSETRLKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKIS-ASG---IIT 723 ++ + T A G ++ T ++ +T +T W SSK + AKIS A+G ++ Sbjct: 856 EIVLDPTSSHKAKGLTENFKATGVFTDNSTKDITDQVTWKSSKTAYAKISNATGSKRVVN 915 Query: 724 AVGKGTTSI 732 A+ KGT+ I Sbjct: 916 AISKGTSHI 924 Score = 59.3 bits (142), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 156/717 (21%), Positives = 282/717 (39%), Gaps = 86/717 (11%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHP 119 +S DIT W SSNT+++ ++N GL + +N G +TA+ + + +VT Sbjct: 342 NSNSDITDQVTWDSSNTDILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFTVTQA 401 Query: 120 FKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNP--NVLTIE 177 ++E S L + L K +G + S KD++ W SS+ +V ++ Sbjct: 402 -ALTSIEVSP----VLPSIAKGLTQKFTAIGIFTDNSKKDITDQVTWNSSSAIVSVSNLD 456 Query: 178 D----GKITLVGEGKSTITAKYKGLTA-TFKAVVQLPYSAIVLKDKAKDTAVKEMELLVG 232 D GK VG+ +TITA ++ T+ VV ++I + + + Sbjct: 457 DNKGLGKAHAVGD--TTITATLGKVSGKTWLTVVPAVLTSI---------QINPVNPSLA 505 Query: 233 DSPVQLSAMTKATESSPEKDIAADANWTTSNESIAKV-----DAGKITIEGTGKAVITAS 287 Q + T + KDI + W +S+ SIA + + G TG I A+ Sbjct: 506 KGLTQKFSATGIYSDNSNKDITSAVTWFSSDSSIATISNAQKNQGNAYGAATGATDIKAT 565 Query: 288 YLGVSKSVDIY--VRAPYEALLLNPEG-DQTLFLGESLRVKSFVRDAVNSSQNQSVRTVW 344 + VS V A + + P + L E + D NS+ + + + W Sbjct: 566 FGKVSSPVSTLSVTAAKLVEIQITPAAASKAKGLTERFKATGIFTD--NSNSDITNQVTW 623 Query: 345 SSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKG------EYLGVSKSFKLTVL-PTL 397 +S N + +G+T+ +G G+ S TV TL Sbjct: 624 NSSN----------TDILTVSNTNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQATL 673 Query: 398 TELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIK-DGKLVGG 456 T + T + ++ TG D +K I++Q+ W S+ + + + G+ G Sbjct: 674 TSIEVSPTRASIAKGMTQKF-TATGIFTDHSKKNITEQVTWKSSSKALSMLNAPGEEGTG 732 Query: 457 KAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPG 516 KA V N + S + LV G + Sbjct: 733 KAIAVGKHYYYCNLRKTFRENRYYRYSRNSYFNSNQSCKNIV-------LVKGLTEKFSA 785 Query: 517 VKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMKGLSKGSAT----LKGTYSN--K 570 +N + D+T + W SN V + K +G + G+ T +K T N Sbjct: 786 TGIYSDNSSK-DITSAVTWH--SSNNSVATISNTKGYQGQAHGTGTGTVDIKATLGNVSS 842 Query: 571 TISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVA 630 +S ++++++++P+ +++ K TG F++ T + + + W+SS TA A Sbjct: 843 QVSRLSVTAAELIEIVLDPTSSHKAKGLTENFKATGVFTDNSTKDITDQVTWKSSKTAYA 902 Query: 631 TVRGTS-----VKAVDEGTATLT---GSYQGITATVKITVVPKLTKLTVSETRLKLAPGA 682 + + V A+ +GT+ ++ GS AT ++T K+ + V + A G Sbjct: 903 KISNATGSKRVVNAISKGTSHISATLGSISSANATFQVTPA-KVVSIEVIPNNISFAKGN 961 Query: 683 SQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKIS----ASGIITAVGKGTTSIKGK 735 S T +Y + A +T W+SS P +A + ++G++ G+T+I K Sbjct: 962 SYQFKATGIYTDHSEADITEQVTWSSSNPKIASVENTFGSAGLVNTTNIGSTNITAK 1018 Score = 57.8 bits (138), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 158/726 (21%), Positives = 284/726 (39%), Gaps = 96/726 (13%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATY---NNAIATLEVSV 116 +S +DIT+A W SS++++ ++N G TG I AT+ ++ ++TL V+ Sbjct: 521 NSNKDITSAVTWFSSDSSIATISNAQKNQGNAYGAATGATDIKATFGKVSSPVSTLSVTA 580 Query: 117 THPFKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTI 176 E+ + ++ K L + K G + S D++ W SSN ++LT+ Sbjct: 581 AK-LVEIQITPAAASKAK------GLTERFKATGIFTDNSNSDITNQVTWNSSNTDILTV 633 Query: 177 EDGKITLVGEGKSTITAKYKGLTATFK-AVVQLPYSAIVLKDKAKDTAVKEMELLVGDSP 235 + T +GL +T K V++ S ++D T + + SP Sbjct: 634 SN-------------TNAKRGLGSTLKQGTVKVTASMGGIEDSVDFTVTQATLTSIEVSP 680 Query: 236 VQLSAMTKATE---------SSPEKDIAADANWTTSNESIAKVDA-GKITIEGTGKAVIT 285 + S T+ +K+I W +S+++++ ++A G+ EGTGKA+ Sbjct: 681 TRASIAKGMTQKFTATGIFTDHSKKNITEQVTWKSSSKALSMLNAPGE---EGTGKAIAV 737 Query: 286 AS---YLGVSKSV--DIYVRAPYEALLLNPEGDQTLFLGESLRVKSFVRDAV---NSSQN 337 Y + K+ + Y R + + + + + L + L K F + NSS++ Sbjct: 738 GKHYYYCNLRKTFRENRYYRYSRNSYFNSNQSCKNIVLVKGLTEK-FSATGIYSDNSSKD 796 Query: 338 QSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSF-KLTVLPT 396 + W S N GT IK VS +L+V Sbjct: 797 ITSAVTWHSSNN----SVATISNTKGYQGQAHGTGTGTVDIKATLGNVSSQVSRLSVTAA 852 Query: 397 -LTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVG 455 L E+ D T +E+ K TG D + +I+DQ+ W S+ +I + Sbjct: 853 ELIEIVLDPTSSHKAKGLTENF-KATGVFTDNSTKDITDQVTWKSSKTAYAKISNAT--- 908 Query: 456 GKAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLP 515 G V K S ++A+ +I S + + P + S G Sbjct: 909 GSKRVVNAISK-GTSHISATLGSISSANATFQVTPAKVVSIEVIPNNI-SFAKGNSYQFK 966 Query: 516 GVKAVLENGDELDVTPTIKWEFS-----------GSNAVVKQTAAGKTMKGLSKGSATLK 564 + + E D+T + W S GS +V T G T +A L Sbjct: 967 AT-GIYTDHSEADITEQVTWSSSNPKIASVENTFGSAGLVNTTNIGST-----NITAKLS 1020 Query: 565 GTYSNKTISIPVTIEQKVVK-LLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWE 623 T S ++ + + +++ +++ PS + +K GT+S+ T + + + W Sbjct: 1021 DTVSGASV---LNVTPALLRYIMITPSYAGIEKGYTKQFSAIGTYSDQSTKDLTEDVTWF 1077 Query: 624 SSNTAVATVRGTSVK-----AVDEGTATLTGSYQGITAT--VKITVVPK-LTKLTVSETR 675 SSN + + T K A + G +T Y T + +TV + +T+S + Sbjct: 1078 SSNPSSVVIENTPGKKGLAFASELGEPDITVFYDHHTQSSYTPVTVTESGIVNITISLSS 1137 Query: 676 LKLAPGASQGVVVTALYDTGNTATVTGSTVWTSSKPSVAKIS----ASGIITAVGKGTTS 731 + G++ T ++ G +T W+SS P+V IS G+ TA+ G++ Sbjct: 1138 ISKTKGSTHQFKATGKFENGAEIDLTELVTWSSSNPTVVSISNVDDERGLATALSVGSSK 1197 Query: 732 IKGKYN 737 I YN Sbjct: 1198 ISVDYN 1203 Score = 55.5 bits (132), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 35/145 (24%), Positives = 72/145 (49%), Gaps = 4/145 (2%) Query: 599 SKSIKVTGTFSNGRTANFSGAMNWESSNTAVATVRGTSVKAVDEGTATLTGSYQGITATV 658 S +++VT F NG N + + + + +V T++G V+ + G++ + Y G+ + Sbjct: 70 STTLEVTAIFDNGTNQNITDSTSIVPDSQSVVTIQGNRVRGIASGSSIIKAEYNGLYSEQ 129 Query: 659 KITVVPK-LTKLTVSETRLKLAP-GASQGVVVTALYDTGNTATVTGS--TVWTSSKPSVA 714 KITV P L + V+ + P G ++ ++ G+ ++ VW+SS P + Sbjct: 130 KITVTPATLNSIQVTSLESGILPKGTNRQFSAIGIFSDGSHQDISNDPLIVWSSSNPDLV 189 Query: 715 KISASGIITAVGKGTTSIKGKYNNK 739 ++ SG+ + + GT I+ + +K Sbjct: 190 QVDDSGLASGINLGTAHIRASFQSK 214 Score = 55.1 bits (131), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 58/231 (25%), Positives = 107/231 (46%), Gaps = 15/231 (6%) Query: 517 VKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMKGLSKGSATLK----GTYSNKTI 572 V A+ +NG ++T + S +VV T G ++G++ GS+ +K G YS + I Sbjct: 75 VTAIFDNGTNQNITDSTSI-VPDSQSVV--TIQGNRVRGIASGSSIIKAEYNGLYSEQKI 131 Query: 573 SI-PVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSG--AMNWESSNTAV 629 ++ P T+ V L E +L ++ G FS+G + S + W SSN + Sbjct: 132 TVTPATLNSIQVTSL-ESGILPKG--TNRQFSAIGIFSDGSHQDISNDPLIVWSSSNPDL 188 Query: 630 ATVRGTSVKA-VDEGTATLTGSYQGITATVKITVVPK-LTKLTVSETRLKLAPGASQGVV 687 V + + + ++ GTA + S+Q ++TV L+++ V+ + G Q ++ Sbjct: 189 VQVDDSGLASGINLGTAHIRASFQSKQGAEEMTVGDAVLSQIQVTSNNPNIPLGKKQKLI 248 Query: 688 VTALYDTGNTATVTGSTVWTSSKPSVAKISASGIITAVGKGTTSIKGKYNN 738 T +Y + ++ S +W SS ++A I +GI+ G +I N Sbjct: 249 ATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTISASSEN 299 >gb|AAP04735.1| LigA [Leptospira kirschneri serovar grippotyphosa] Length = 1224 Score = 76.3 bits (186), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 157/697 (22%), Positives = 290/697 (41%), Gaps = 94/697 (13%) Query: 66 SKRDITAAAIWTSSNTNVVKVANGLLTAVNTGTAMITATYNNAIATLEVSVTHP-FKELT 124 + ++IT + S ++V + + + +G+++I A YN + +++VT + Sbjct: 83 TNQNITDSTSIVSDAQSIVDIQGNRVRGIASGSSIIKAEYNGMYSEQKITVTPATINSIQ 142 Query: 125 LERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADA--DWTSSNPNVLTIED-GKI 181 + DG G + + +G S S +D+S D W+SSN +++ ++D G Sbjct: 143 VTSLDDGILPKGTNRQ-----FAAIGIFSDGSHQDISNDPLIVWSSSNIDLVRVDDSGLA 197 Query: 182 TLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVGDSPVQLSAM 241 + + G + I A ++ A+ + V D + +++ + L Sbjct: 198 SGINLGTAHIRASFQSKQASEEITV-------------GDAVLSSIQVTSNSPNIPLGKK 244 Query: 242 TKATES-----SPEKDIAADANWTTSNESIAKV-DAGKITIEGTGKAVITASYLGVSKSV 295 K T + + +DI++ W +SN +IA + + G + TG ++AS ++ S+ Sbjct: 245 QKLTATGIYSDNSNRDISSSVIWNSSNSTIANIQNNGILETADTGIVTVSASRGNINGSI 304 Query: 296 DIYVR-APYEALLLNPEGDQTL-FLGESLRVKSFVRDAVNSSQNQSVRTVWSSDNQLXXX 353 + V A ++ ++P L E+ + D NS+ + + + W S N Sbjct: 305 KLIVTPAALVSISVSPTNSAVAKGLQENFKATGIFTD--NSNSDITDQVTWDSSNPDILS 362 Query: 354 XXXXXXXXXXXXXXXXXKAVGTTVIKGEYLGVSKSFKLT--------VLPTLTELTADKT 405 T I G + S FK+T V P L + T Sbjct: 363 ISNASDSHGLASTLNQGNVKVTASIGG--IQGSTDFKVTQEVLTSIEVSPVLPSIAKGLT 420 Query: 406 EQELFTADSESLPKVTGTKYDGTKLEISDQIEW--TSADEEIVRIKDGKLVG--GKAGTV 461 ++ FTA G D +K +I++Q+ W +SA + + D K +G G Sbjct: 421 QK--FTA--------IGIFTDNSKKDITNQVTWNSSSAIASVSNLDDNKGLGKAHAVGDT 470 Query: 462 TLT---GKIKNST-VAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPGV 517 T+T GK+ T P+ + S I P +P SL G + Sbjct: 471 TITATLGKVSGKTWFTVVPAVLTS--------------IQINPVNP-SLAKGLTQKFTAT 515 Query: 518 KAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMKGLSKGSAT----LKGTYSNKTIS 573 +N ++ D+T ++ W FS S++ + + K +G S G+AT +K T+ +S Sbjct: 516 GIYSDNSNK-DITSSVTW-FS-SDSSIATISNAKKNQGNSYGAATGATDIKATFGK--VS 570 Query: 574 IPVTI----EQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAV 629 PV+ K+V++ + P+ S+ K TG F++ ++ + + W SSNT + Sbjct: 571 SPVSTLSVTAAKLVEIQITPAAASKAKGISERFKATGIFTDNSNSDITNQVTWSSSNTDI 630 Query: 630 ATVRGTSVK-----AVDEGTATLTGSYQGITATVKITVV-PKLTKLTVSETRLKLAPGAS 683 TV T+ K + +GT + S GI ++V TV LT + VS TR +A G + Sbjct: 631 LTVSNTNAKRGLGSTLKQGTVKVIASMGGIESSVDFTVTQANLTSIEVSPTRSSIAKGLT 690 Query: 684 QGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISASG 720 Q ++ + +T W SS + ++ASG Sbjct: 691 QKFTAIGIFTDHSKKDITEQVTWKSSSKVLNMLNASG 727 Score = 65.1 bits (157), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 168/725 (23%), Positives = 296/725 (40%), Gaps = 109/725 (15%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHP 119 +S DIT W SSN +++ ++N GL + +N G +TA+ + + VT Sbjct: 342 NSNSDITDQVTWDSSNPDILSISNASDSHGLASTLNQGNVKVTASIGGIQGSTDFKVTQE 401 Query: 120 FKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNP--NVLTIE 177 ++E S L + L K +G + S KD++ W SS+ +V ++ Sbjct: 402 VLT-SIEVSP----VLPSIAKGLTQKFTAIGIFTDNSKKDITNQVTWNSSSAIASVSNLD 456 Query: 178 D----GKITLVGEGKSTITAKYKGLTA-TFKAVVQLPYSAIVLKDKAKDTAVKEMELLVG 232 D GK VG+ +TITA ++ T+ VV ++I + + + Sbjct: 457 DNKGLGKAHAVGD--TTITATLGKVSGKTWFTVVPAVLTSI---------QINPVNPSLA 505 Query: 233 DSPVQLSAMTKATESSPEKDIAADANWTTSNESIA-----KVDAGKITIEGTGKAVITAS 287 Q T + KDI + W +S+ SIA K + G TG I A+ Sbjct: 506 KGLTQKFTATGIYSDNSNKDITSSVTWFSSDSSIATISNAKKNQGNSYGAATGATDIKAT 565 Query: 288 YLGVSKSVDIY--VRAPYEALLLNPEG-DQTLFLGESLRVKSFVRDAVNSSQNQSVRTVW 344 + VS V A + + P + + E + D NS+ + + + W Sbjct: 566 FGKVSSPVSTLSVTAAKLVEIQITPAAASKAKGISERFKATGIFTD--NSNSDITNQVTW 623 Query: 345 SSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKG------EYLGVSKSFKLTVL-PTL 397 SS N + +G+T+ +G G+ S TV L Sbjct: 624 SSSN----------TDILTVSNTNAKRGLGSTLKQGTVKVIASMGGIESSVDFTVTQANL 673 Query: 398 TELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIK-DGKLVGG 456 T + T + ++ + G D +K +I++Q+ W S+ + + + G+ G Sbjct: 674 TSIEVSPTRSSIAKGLTQKFTAI-GIFTDHSKKDITEQVTWKSSSKVLNMLNASGEEGRG 732 Query: 457 KA---GTVTLTGKIKN----STVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIG 509 KA G T+T ++ + + +P+ + S I P P SLV G Sbjct: 733 KAISVGKATITATLEKLSGKADITVTPAVLTS--------------IQISPVKP-SLVKG 777 Query: 510 EEKPLPGVKAVLENGDELDVTPTIKWE-FSGSNAVVKQTAAGKTMKGLSKGSAT----LK 564 + +N + D+T ++ W F+ S A + T K G + + T +K Sbjct: 778 LTENFSATGIYSDNSSK-DITSSVTWHSFNNSVATISNT---KNYHGQAHATGTGIVGIK 833 Query: 565 GTYSNKTISIPVT----IEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAM 620 T N +S PV+ ++V++++ P++ +++ K TG F++ T + + + Sbjct: 834 ATLGN--VSSPVSKLSVTAAELVEIVLNPTLSHKAKGLTENFKATGVFTDNSTKDITDQV 891 Query: 621 NWESSNTAVATVRGTS-----VKAVDEGTATLT---GSYQGITATVKITVVPKLTKLTVS 672 W+SSNTA A + + V A+ +GT+ ++ GS AT ++T K+ + ++ Sbjct: 892 TWKSSNTAYAEISNATGSKGVVNALSKGTSHISATLGSISSANATFQVTPA-KIASIEIT 950 Query: 673 ETRLKLAPGASQGVVVTALYDTGNTAT-VTGSTVWTSSKPSVAKI----SASGIITAVGK 727 L S +Y T NT T +T W+SS P+VA I S +G TA+ Sbjct: 951 PNNFFLIKKLSYPFKAIGIY-TDNTKTDITKQVSWSSSDPNVASIDNTFSLAGSATAIDD 1009 Query: 728 GTTSI 732 G T+I Sbjct: 1010 GKTNI 1014 Score = 63.2 bits (152), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 150/657 (22%), Positives = 262/657 (39%), Gaps = 107/657 (16%) Query: 65 SSKRDITAAAIWTSSNTNVVKVAN-----GLLTAVNTGTAMITATYNNAIATLEVSVTHP 119 +S DIT W+SSNT+++ V+N GL + + GT + A+ ++++ +VT Sbjct: 612 NSNSDITNQVTWSSSNTDILTVSNTNAKRGLGSTLKQGTVKVIASMGGIESSVDFTVTQA 671 Query: 120 FK---ELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNP--NVL 174 E++ RSS + L K +G + S KD++ W SS+ N+L Sbjct: 672 NLTSIEVSPTRSSIA--------KGLTQKFTAIGIFTDHSKKDITEQVTWKSSSKVLNML 723 Query: 175 TI--EDGKITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELLVG 232 E+G+ + GK+TITA + L+ KA T + + Sbjct: 724 NASGEEGRGKAISVGKATITATLEKLSG-----------------KADITVTPAVLTSIQ 766 Query: 233 DSPVQLSAMTKATES---------SPEKDIAADANWTTSNESIAKVD-----AGKITIEG 278 SPV+ S + TE+ + KDI + W + N S+A + G+ G Sbjct: 767 ISPVKPSLVKGLTENFSATGIYSDNSSKDITSSVTWHSFNNSVATISNTKNYHGQAHATG 826 Query: 279 TGKAVITASYLGVSKSVDIY--VRAPYEALLLNPE-GDQTLFLGESLRVKSFVRDAVNSS 335 TG I A+ VS V A ++LNP + L E+ + D NS+ Sbjct: 827 TGIVGIKATLGNVSSPVSKLSVTAAELVEIVLNPTLSHKAKGLTENFKATGVFTD--NST 884 Query: 336 QNQSVRTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTVIKG-----EYLGVSKSFK 390 ++ + + W S N K V + KG LG S Sbjct: 885 KDITDQVTWKSSN----------TAYAEISNATGSKGVVNALSKGTSHISATLGSISSAN 934 Query: 391 LTVLPTLTELTA-DKTEQELFTADSESLP-KVTGTKYDGTKLEISDQIEWTSADEEIVRI 448 T T ++ + + T F S P K G D TK +I+ Q+ W+S+D + I Sbjct: 935 ATFQVTPAKIASIEITPNNFFLIKKLSYPFKAIGIYTDNTKTDITKQVSWSSSDPNVASI 994 Query: 449 KDGKLVGGKA-----GTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDP 503 + + G A G +T + +S A++ + S + P Sbjct: 995 DNTFSLAGSATAIDDGKTNITATLSDSMSASTTLYVTSATLVDIEVK------------P 1042 Query: 504 QSLVIGEEKPLP-GVKAVLENGDELDVTPTIKWEFSGSNAVVKQTAAGKTMK--GLSKGS 560 V+ E L + + D+T + W S + + + AGK K L+ G+ Sbjct: 1043 SIFVLSEGLTLQLTATGIYSDYSTYDLTQVVTWTSSEPSNISIENTAGKKGKVTALAFGA 1102 Query: 561 ATLKGTY----SNKTISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANF 616 + TY SN+ I V ++K V + + S + + ++ K GTF G + Sbjct: 1103 SEFTATYDSIESNRAW-IFVN-DEKFVNITISSSQVLTDKGLTQQFKAIGTFEKGSELDL 1160 Query: 617 SGAMNWESSNTAVATV------RGTSVKAVDEGTATLTGSYQGITA-TVKITVVPKL 666 + + W+SS++ VA++ RG + + G++ ++ +Y I + ++ V P++ Sbjct: 1161 TDLVTWKSSDSKVASIGNSNDDRGL-ITPLSVGSSKISATYNSIHSNSIDFEVTPEI 1216 Score = 60.1 bits (144), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 165/718 (22%), Positives = 291/718 (40%), Gaps = 82/718 (11%) Query: 65 SSKRDITAAAIWTSSNTNVVKVANGLLTAVN-----TGTAMITATY---NNAIATLEVSV 116 +S +DIT++ W SS++++ ++N N TG I AT+ ++ ++TL V+ Sbjct: 521 NSNKDITSSVTWFSSDSSIATISNAKKNQGNSYGAATGATDIKATFGKVSSPVSTLSVTA 580 Query: 117 THPFKELTLERSSDGNYKLGDSEESLQVKAKVVGGESATSVKDVSADADWTSSNPNVLTI 176 E+ + ++ K G SE + K G + S D++ W+SSN ++LT+ Sbjct: 581 AK-LVEIQITPAAASKAK-GISE-----RFKATGIFTDNSNSDITNQVTWSSSNTDILTV 633 Query: 177 EDGKITLVGEGKSTITAKYKGLTATFKAVVQLPYSAIVLKDKAKDTAVKEMELL-VGDSP 235 + T +GL +T K +++ + + D V + L + SP Sbjct: 634 SN-------------TNAKRGLGSTLKQGTVKVIASMGGIESSVDFTVTQANLTSIEVSP 680 Query: 236 VQLSAMTKATE---------SSPEKDIAADANWTTSNESIAKVDA----GKITIEGTGKA 282 + S T+ +KDI W +S++ + ++A G+ GKA Sbjct: 681 TRSSIAKGLTQKFTAIGIFTDHSKKDITEQVTWKSSSKVLNMLNASGEEGRGKAISVGKA 740 Query: 283 VITASYLGVSKSVDIYVR-APYEALLLNPEGDQTL-FLGESLRVKSFVRDAVNSSQNQSV 340 ITA+ +S DI V A ++ ++P + L E+ D NSS++ + Sbjct: 741 TITATLEKLSGKADITVTPAVLTSIQISPVKPSLVKGLTENFSATGIYSD--NSSKDITS 798 Query: 341 RTVWSSDNQLXXXXXXXXXXXXXXXXXXXXKAVGTTV--IKGEYLGVSKSF-KLTVLPT- 396 W S N A GT + IK VS KL+V Sbjct: 799 SVTWHSFNN------SVATISNTKNYHGQAHATGTGIVGIKATLGNVSSPVSKLSVTAAE 852 Query: 397 LTELTADKTEQELFTADSESLPKVTGTKYDGTKLEISDQIEWTSADEEIVRIKDGKLVGG 456 L E+ + T +E+ K TG D + +I+DQ+ W S++ I + G Sbjct: 853 LVEIVLNPTLSHKAKGLTENF-KATGVFTDNSTKDITDQVTWKSSNTAYAEISNAT---G 908 Query: 457 KAGTVTLTGKIKNSTVAASPSAIRSKSXXXXXXXXXXXXXXIGPEDPQSLVIGEEKPLPG 516 G V K S ++A+ +I S + I P + L+ P Sbjct: 909 SKGVVNALSK-GTSHISATLGSISSANATFQVTPAKIASIEITPNN-FFLIKKLSYPFKA 966 Query: 517 VKAVLENGDELDVTPTIKWEFSGSN-AVVKQT-----AAGKTMKGLSKGSATLKGTYSNK 570 + +N + D+T + W S N A + T +A G + +ATL + S Sbjct: 967 IGIYTDN-TKTDITKQVSWSSSDPNVASIDNTFSLAGSATAIDDGKTNITATLSDSMSAS 1025 Query: 571 TISIPVTIEQKVVKLLVEPSVLEMNIKASKSIKVTGTFSNGRTANFSGAMNWESSNTAVA 630 T ++ VT +V + V+PS+ ++ + + TG +S+ T + + + W SS + Sbjct: 1026 T-TLYVT-SATLVDIEVKPSIFVLSEGLTLQLTATGIYSDYSTYDLTQVVTWTSSEPSNI 1083 Query: 631 TVRGTS-----VKAVDEGTATLTGSYQGITATVKITVV--PKLTKLTVSETRLKLAPGAS 683 ++ T+ V A+ G + T +Y I + V K +T+S +++ G + Sbjct: 1084 SIENTAGKKGKVTALAFGASEFTATYDSIESNRAWIFVNDEKFVNITISSSQVLTDKGLT 1143 Query: 684 QGVVVTALYDTGNTATVTGSTVWTSSKPSVAKISAS----GIITAVGKGTTSIKGKYN 737 Q ++ G+ +T W SS VA I S G+IT + G++ I YN Sbjct: 1144 QQFKAIGTFEKGSELDLTDLVTWKSSDSKVASIGNSNDDRGLITPLSVGSSKISATYN 1201 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.308 0.124 0.331 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 933,035,703 Number of extensions: 35464154 Number of successful extensions: 96777 Number of sequences better than 1.0e-05: 29 Number of HSP's gapped: 96156 Number of HSP's successfully gapped: 140 Length of query: 748 Length of database: 757,237,578 Length adjustment: 133 Effective length of query: 615 Effective length of database: 396,129,411 Effective search space: 243619587765 Effective search space used: 243619587765 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 130 (54.7 bits)