BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0052.p (390 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00182777.1| hypothetical protein Exigu186001 [Exiguobacte... 352 8e-96 ref|NP_470849.1| highly similar to coproporphyrinogen III oxidas... 350 2e-95 ref|NP_465001.1| highly similar to coproporphyrinogen III oxidas... 348 1e-94 ref|NP_242209.1| coproporphyrinogen III oxidase [Bacillus halodu... 340 2e-92 ref|NP_390428.1| coproporphyrinogen III oxidase [Bacillus subtil... 338 1e-91 >ref|ZP_00182777.1| hypothetical protein Exigu186001 [Exiguobacterium sp. 255-15] Length = 381 Score = 352 bits (903), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 173/377 (45%), Positives = 241/377 (63%), Gaps = 4/377 (1%) Query: 10 PEAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGG 69 P A Y+HIPFC + C+YCDFN LK+QPV +YL AL+RE+E+T++H ++TIF+GG Sbjct: 3 PRAAYVHIPFCEHICYYCDFNKVFLKNQPVAEYLDALEREIELTLQHYPTDRLETIFIGG 62 Query: 70 GTPTVLKPEEMAYFLKSVRTHF-PQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFG 128 GTPT L +M + + H P D +E+++E+NP +KL +MK GGVNRVSFG Sbjct: 63 GTPTALNEAQMQRLMDIISKHLLPLTDATLEYTVESNPDGVSPEKLDIMKAGGVNRVSFG 122 Query: 129 VQAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKAL 188 VQ+F + LL IGR H V +L++A + N+SVDLMFGLPNQT++ +R V +AL Sbjct: 123 VQSFDDGLLERIGRTHREAKVAETLDHA-AKRFDNISVDLMFGLPNQTLEQVRYDVKRAL 181 Query: 189 ELNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISN 248 L + H S YSL +E +T+F K KLPLP+ T+EA G QYEISN Sbjct: 182 HLPITHISSYSLILEPHTVFAIQERKGKLPLPTQDLEADMYRLMIETIEAGGLHQYEISN 241 Query: 249 FAKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSGLPRLDTFR 308 F+ PG ESRHN YW N++YYG GAG+H Y+ + R NI + YI+A GLP + Sbjct: 242 FSLPGRESRHNRVYWENDEYYGFGAGSHSYINKTRRANIAPIPHYIKA--EGLPVRNETP 299 Query: 309 ISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRL 368 ++E E ME+ M +GLRM+EGVS++ F ++G SL +F ++ K+L GL+E+ RL Sbjct: 300 LTEVERMEEEMFLGLRMKEGVSERHFEEKYGHSLDRVFGQTIAKLLPRGLVERTATHLRL 359 Query: 369 SKQGILFGNDVFGEFVG 385 + G+ N+VF EF+G Sbjct: 360 TDAGVPLANEVFAEFIG 376 >ref|NP_470849.1| highly similar to coproporphyrinogen III oxidase [Listeria innocua] pir||AH1621 coproporphyrinogen III oxidase homolog hemN [imported] - Listeria innocua (strain Clip11262) emb|CAC96744.1| hemN [Listeria innocua] Length = 385 Score = 350 bits (899), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 176/374 (47%), Positives = 234/374 (62%), Gaps = 2/374 (0%) Query: 12 AVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGGT 71 AVYIHIPFC + C+YCDFN L+ QPV +Y+ L +EMEMT + T+FVGGGT Sbjct: 13 AVYIHIPFCEHICYYCDFNKVFLEGQPVDEYVDLLIKEMEMTAAKGPIAPVDTVFVGGGT 72 Query: 72 PTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGVQA 131 PT L ++A ++R P +E IEFS EANPG KL M++ GVNR+S GVQ+ Sbjct: 73 PTTLNEAQIARLCTAIREILPLKNE-IEFSFEANPGDLSISKLQAMQDHGVNRISMGVQS 131 Query: 132 FQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALELN 191 F NELL IGRIH V DVY+S+EN R VG N+S+DL+F LP QT ++++ +AL+L+ Sbjct: 132 FNNELLKKIGRIHTVKDVYQSVENMRKVGFENVSIDLIFSLPGQTEADFKDTLKQALDLD 191 Query: 192 LPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNFAK 251 LPHYS YSL +E T+F+ L K KL LP + ME G QYEISNFAK Sbjct: 192 LPHYSAYSLIIEPKTIFYNLMQKGKLFLPGQDAEANMYDLLLTEMEKHGRKQYEISNFAK 251 Query: 252 PGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEA-SHSGLPRLDTFRIS 310 G +S+HNITYW NE YYG GAGAHGYV R+ N + Y+E + LP ++ Sbjct: 252 EGFQSKHNITYWSNEHYYGFGAGAHGYVGNTRYSNFGPIKKYMEPLQENKLPTFQQKELT 311 Query: 311 EQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRLSK 370 +E ME+ M +GLR +GV+ F+ +FG+ L FA +++K A G +E N + L++ Sbjct: 312 LKEKMEEEMFLGLRKVDGVNKIHFKQKFGQDLDTTFAHAIQKTTAKGWLENNEENVALTR 371 Query: 371 QGILFGNDVFGEFV 384 G GN+VF EF+ Sbjct: 372 SGRFLGNNVFQEFL 385 >ref|NP_465001.1| highly similar to coproporphyrinogen III oxidase [Listeria monocytogenes EGD-e] pir||AD1259 coproporphyrinogen III oxidase homolog hemN [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC99554.1| hemN [Listeria monocytogenes] Length = 385 Score = 348 bits (894), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 173/374 (46%), Positives = 233/374 (62%), Gaps = 2/374 (0%) Query: 12 AVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGGT 71 AVYIHIPFC + C+YCDFN L+ QPV +Y+ L +EME+TV + T+FVGGGT Sbjct: 13 AVYIHIPFCEHICYYCDFNKVFLEGQPVDEYVDLLIKEMELTVAKGPIAPVDTVFVGGGT 72 Query: 72 PTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGVQA 131 PT L ++A ++ P ++IEFS EANPG KL M++ GVNR+S GVQ+ Sbjct: 73 PTTLNEAQIARLCTAIHNTLP-LKKDIEFSFEANPGDLSLSKLQAMQDHGVNRISMGVQS 131 Query: 132 FQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALELN 191 F NELL IGRIH V DVY+S+EN R +G N+S+DL+F LP QT ++++ +AL+L+ Sbjct: 132 FNNELLKKIGRIHTVKDVYQSVENMRKIGFENVSIDLIFSLPGQTEADFQDTLKQALDLD 191 Query: 192 LPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNFAK 251 LPHYS YSL +E T+F+ L K KL LP + ME G QYEISNFAK Sbjct: 192 LPHYSAYSLIIEPKTIFYNLMQKGKLFLPGQDAEANMYDLLLNEMEKHGRKQYEISNFAK 251 Query: 252 PGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSG-LPRLDTFRIS 310 G +S+HNITYW NE YYG GAGAHGYV R+ N + Y+E LP ++ Sbjct: 252 EGFQSKHNITYWSNEHYYGFGAGAHGYVGNTRYSNFGPIKKYMEPLQENILPTFQQKELT 311 Query: 311 EQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRLSK 370 +E ME+ M +GLR +GV + F+ +FG+ L FA +++K A G +E N + L++ Sbjct: 312 LKEKMEEEMFLGLRKVDGVDKKHFKQKFGQDLDATFANAIQKTTAKGWLENNEENVALTR 371 Query: 371 QGILFGNDVFGEFV 384 G GN+VF EF+ Sbjct: 372 SGRFLGNNVFQEFL 385 >ref|NP_242209.1| coproporphyrinogen III oxidase [Bacillus halodurans] pir||G83817 coproporphyrinogen III oxidase hemN [imported] - Bacillus halodurans (strain C-125) dbj|BAB05062.1| coproporphyrinogen III oxidase [Bacillus halodurans] Length = 385 Score = 340 bits (873), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 168/381 (44%), Positives = 239/381 (62%), Gaps = 2/381 (0%) Query: 10 PEAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGG 69 P+A YIHIPFC + C+YCDFN + LK+QPV +YL+AL+ EM M V ++T++VGG Sbjct: 2 PKAAYIHIPFCEHICYYCDFNKFYLKNQPVNEYLQALETEMAMVVAEQPTKSLQTLYVGG 61 Query: 70 GTPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGV 129 GTPT L +++A L S++ P D EF+ E NP + D++KL V++ GV+R+S GV Sbjct: 62 GTPTALTADQLAQLLASIKRTLPLSDLE-EFTFEVNPDSIDEEKLDVLRSYGVDRLSIGV 120 Query: 130 QAFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALE 189 QAFQ LL IGR H+ V +++E +R G NLS+DLM GLP QT +M E++ +A Sbjct: 121 QAFQPLLLKEIGRTHDQKSVEQAVEKSRQAGFANLSLDLMLGLPKQTPEMFAETLKEAFA 180 Query: 190 LNLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNF 249 L + H S YSLKVE T+F+ + +L LP E G+ QYEISNF Sbjct: 181 LEVEHLSCYSLKVEAKTVFYNRQRQGRLTLPPEDDEVKMYRQLCYETEKHGFKQYEISNF 240 Query: 250 AKPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIEASHSG-LPRLDTFR 308 AK G ESRHN+ YW N++YYG GAGAHGYV R+MN + Y++A G P ++ Sbjct: 241 AKKGYESRHNLVYWNNDEYYGFGAGAHGYVGGVRYMNHGPLPKYLQAMEEGRRPVFESHH 300 Query: 309 ISEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRL 368 +S E ME+ M +GLR R GV ++ F +FG S+ ++ + +++A L+E+ D RL Sbjct: 301 VSRVEQMEEQMFLGLRKRSGVEERVFVERFGVSMFSLYEKQIAQLVARCLLERTDDRVRL 360 Query: 369 SKQGILFGNDVFGEFVGVLTE 389 + +G+L GN+VF +F+ VL E Sbjct: 361 TDEGLLLGNEVFEQFLAVLDE 381 >ref|NP_390428.1| coproporphyrinogen III oxidase [Bacillus subtilis] sp|P54304|HEMN_BACSU Probable oxygen-independent coproporphyrinogen III oxidase (Coproporphyrinogenase) (Coprogen oxidase) pir||B69640 coproporphyrinogen oxidase (EC 1.3.3.3) III, oxygen-independent hemN - Bacillus subtilis dbj|BAA12461.1| YqeR [Bacillus subtilis] emb|CAB14492.1| coproporphyrinogen III oxidase [Bacillus subtilis subsp. subtilis str. 168] Length = 366 Score = 338 bits (868), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 166/363 (45%), Positives = 227/363 (62%), Gaps = 1/363 (0%) Query: 11 EAVYIHIPFCTNKCFYCDFNSYVLKDQPVMDYLRALDREMEMTVKHTTPGVIKTIFVGGG 70 ++ YIHIPFC + C YCDFN Y ++ QPV +YL AL++EM T+ T +KTIF+GGG Sbjct: 2 KSAYIHIPFCEHICHYCDFNKYFIQSQPVDEYLNALEQEMINTIAKTGQPDLKTIFIGGG 61 Query: 71 TPTVLKPEEMAYFLKSVRTHFPQWDENIEFSMEANPGTTDKDKLAVMKEGGVNRVSFGVQ 130 TPT L E++ + + + EF+++ANP +KL ++KE GVNR+SFGVQ Sbjct: 62 TPTSLSEEQLKKLMDMINRVLKPSSDLSEFAVDANPDDLSAEKLKILKEAGVNRLSFGVQ 121 Query: 131 AFQNELLSGIGRIHNVDDVYRSLENARSVGLHNLSVDLMFGLPNQTVDMLRESVSKALEL 190 F+++LL IGR+H DV+ S E AR +G N+S+DLMFGLP QT+ L S++ AL L Sbjct: 122 TFEDDLLEKIGRVHKQKDVFTSFERAREIGFENISLDLMFGLPGQTLKHLEHSINTALSL 181 Query: 191 NLPHYSIYSLKVEENTLFHTLFNKNKLPLPSXXXXXXXXXXXXSTMEAAGYGQYEISNFA 250 + HYS+YSL VE T+F+ L K +L LP S MEA G QYEISNFA Sbjct: 182 DAEHYSVYSLIVEPKTVFYNLMQKGRLHLPPQEQEAEMYEIVMSKMEAHGIHQYEISNFA 241 Query: 251 KPGMESRHNITYWRNEDYYGLGAGAHGYVKRQRHMNIKGVNPYIE-ASHSGLPRLDTFRI 309 K GMES+HN+TYW NE Y+G GAGAHGY+ R +N+ V YI+ + G P DT + Sbjct: 242 KAGMESKHNLTYWSNEQYFGFGAGAHGYIGGTRTVNVGPVKHYIDLIAEKGFPYRDTHEV 301 Query: 310 SEQEAMEDFMMVGLRMREGVSDQAFRAQFGKSLQDIFAGSLKKMLAAGLIEQNGDAYRLS 369 + +E +E+ M +GLR GVS + F ++G+SL +F LK + GLI + A L+ Sbjct: 302 TTEEQIEEEMFLGLRKTAGVSKKRFAEKYGRSLDGLFPSVLKDLAEKGLIHNSESAVYLT 361 Query: 370 KQG 372 QG Sbjct: 362 HQG 364 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.137 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 576,941,704 Number of extensions: 23517571 Number of successful extensions: 52254 Number of sequences better than 1.0e-05: 520 Number of HSP's gapped: 51019 Number of HSP's successfully gapped: 521 Length of query: 390 Length of database: 757,237,578 Length adjustment: 128 Effective length of query: 262 Effective length of database: 409,704,906 Effective search space: 107342685372 Effective search space used: 107342685372 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)