BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0290.0035.p (543 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_349361.1| MDR-type ABC transporter (membrane associated A... 570 e-161 ref|NP_622488.1| ABC-type multidrug/protein/lipid transport syst... 438 e-121 ref|NP_951163.1| ABC transporter, ATP-binding/permease protein [... 355 2e-96 ref|ZP_00080324.1| COG1132: ABC-type multidrug transport system,... 343 5e-93 ref|NP_980011.1| ABC transporter, ATP-binding/permease protein [... 335 3e-90 >ref|NP_349361.1| MDR-type ABC transporter (membrane associated ATPase) [Clostridium acetobutylicum] pir||B97239 MDR-type ABC transporter (membrane associated ATPase) CAC2756 [imported] - Clostridium acetobutylicum gb|AAK80701.1| MDR-type ABC transporter (membrane associated ATPase) [Clostridium acetobutylicum] Length = 592 Score = 570 bits (1469), Expect = e-161, Method: Compositional matrix adjust. Identities = 285/535 (53%), Positives = 367/535 (68%) Query: 1 LLQRVIDHFLIGGAVERGLDSIGGXXXXXXXXXXXXXXXXXXQALIVGKAGQSLIHELRV 60 +L+ ID FL+G V+ G SI +A ++ A QS++ LR Sbjct: 53 ILKVSIDDFLVGKRVQSGFYSISSMGFLYFGVVALGGFFSISEANLINSAAQSIMKGLRS 112 Query: 61 RVFSIIERLPLPYLDRTSSGRLITRATNDTSEISDLYTDVIISLVKDVLLLAGIVYAMLV 120 VF I+ LPL YLD+TSSG LITRATND +S++YTDVIISL +D+ LL GI+YAML Sbjct: 113 SVFKTIQLLPLSYLDKTSSGSLITRATNDVEALSEMYTDVIISLFQDIFLLLGIIYAMLS 172 Query: 121 LSPKLTLVSXXXXXXXXXXXXXXXXXXXXXXXHMKHYIGQINGFIAESISGMRVIQIFRA 180 L+ +L+L+S MK IG+INGF+AE++SGM+++QIF A Sbjct: 173 LNIELSLISFSVIPIMFFLVFSLKTRIKRNFAKMKSLIGKINGFMAENLSGMKLVQIFTA 232 Query: 181 EKEKEQQFLKLNGEYFNTTLIQVRLNSILKPASDMFQSLAIAILVWYSVGRIAGGTLQIG 240 EKEK ++F LN EYFN TL QVRLNSIL+PAS++FQ+L+IA+L+WY + +IA T+QIG Sbjct: 233 EKEKRREFKALNNEYFNATLFQVRLNSILRPASNVFQNLSIALLLWYGMAKIANHTIQIG 292 Query: 241 VLYAFTTYIKQFFAPVSDLADKYTSIQSAFVSTXXXXXXXXXXXXXXXPDAGLPMQRLNG 300 VLYAFT+YI+QFF P+SDLAD YT+IQSA VS G+PM+++ G Sbjct: 293 VLYAFTSYIRQFFDPISDLADSYTTIQSALVSADRIFELLDKKIILEDLHKGIPMKKIEG 352 Query: 301 RIEFRRVWFSYNGADWVLKDVSFVIEKGQTAAFIGETGAGKTTIISLINGFYKVQKGEIL 360 +EF+ VWFSY+ +++LK ++F I KG+TAAF+GETGAGKTTIISLI+GFYKVQKGEIL Sbjct: 353 DVEFKDVWFSYDNKNFILKGLNFKINKGETAAFVGETGAGKTTIISLISGFYKVQKGEIL 412 Query: 361 IDGVNVNDIRLDDLRRNISVVLQDVFLFSGTIRXXXXXXXXXXXXXXXXALRASCAEAFV 420 IDGVN+N IR DLR+N++VVLQDVFLFSG I+ A+ AS A+ F+ Sbjct: 413 IDGVNINSIRPSDLRKNVAVVLQDVFLFSGNIKSNITLNDFVPEDVINSAVEASFAKDFI 472 Query: 421 HSAPEGIDEPVTERGSTLSAGQRQLISFARAIAHDPAIFVLDEATANIDTRTEKLIQQAI 480 P ++EPV ERG T SAGQ+QL+SFARAIAH P+IFVLDEATANIDT TEKLIQ+AI Sbjct: 473 EKLPNKLNEPVMERGKTFSAGQKQLLSFARAIAHTPSIFVLDEATANIDTYTEKLIQKAI 532 Query: 481 DNAASGRTTLIIAHRLSTITGADLIIAMKAGRIAESGHPRELLKRGGYYAKLLQE 535 +N +TT IIAHRLSTI AD I+ + G+I E G+ EL+K+ GYY L+ E Sbjct: 533 ENITRDKTTFIIAHRLSTIRNADKILVIDNGKIVEMGNHNELMKKDGYYRNLVYE 587 >ref|NP_622488.1| ABC-type multidrug/protein/lipid transport system, ATPase component [Thermoanaerobacter tengcongensis] gb|AAM24092.1| ABC-type multidrug/protein/lipid transport system, ATPase component [Thermoanaerobacter tengcongensis] Length = 601 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 217/503 (43%), Positives = 316/503 (62%), Gaps = 2/503 (0%) Query: 43 QALIVGKAGQSLIHELRVRVFSIIERLPLPYLDRTSSGRLITRATNDTSEISDLYTDVII 102 Q ++ GQ +I LR ++F +++L L + DR GRL+TR TNDT ++++YT VI Sbjct: 96 QVYLIQYTGQKIIFNLRQQIFEHLQKLSLSFFDRNPVGRLVTRVTNDTDTLNEMYTSVIT 155 Query: 103 SLVKDVLLLAGIVYAMLVLSPKLTLVSXXXXXXXXXXXXXXXXXXXXXXXHMKHYIGQIN 162 +L DV ++AGIV AM+ + KL ++ ++ + +IN Sbjct: 156 NLFNDVFIIAGIVIAMVSYNLKLAFIALSTTPLILTGMYIYRKLASQAYRLVRVRLARIN 215 Query: 163 GFIAESISGMRVIQIFRAEKEKEQQFLKLNGEYFNTTLIQVRLNSILKPASDMFQSLAIA 222 F++E ISGM+++Q+F E +K ++F K+N EY++ + Q+ + +I +P+ D+ SL +A Sbjct: 216 AFLSEHISGMKIVQLFVTENKKMEEFKKINKEYYDANMRQLTIFAIFRPSMDVIYSLTLA 275 Query: 223 ILVWYSVGRIAGGTLQIGVLYAFTTYIKQFFAPVSDLADKYTSIQSAFVSTXXXXXXXXX 282 +L+WY I G ++ GVLYAF Y++Q F P+ D+++KY +QSA S Sbjct: 276 LLIWYGGRDIIAGKIEFGVLYAFVNYLQQLFQPIFDISEKYDILQSAMASAERIFILLDT 335 Query: 283 XXXXXXPDAGLPMQRLNGRIEFRRVWFSYNGADWVLKDVSFVIEKGQTAAFIGETGAGKT 342 P+ +P++ + G+IEF+ VWFSYNG +WVLKDVSF + G+T AF+G TGAGKT Sbjct: 336 KEEVKDPEDPIPLEEVKGKIEFKNVWFSYNGKEWVLKDVSFEVNPGETVAFVGATGAGKT 395 Query: 343 TIISLINGFYKVQKGEILIDGVNVNDIRLDDLRRNISVVLQDVFLFSGTIRXXXXXXXXX 402 +II+L+ FY +QKGEILIDG+++ +R DLR++I +VLQDVFLF+G I+ Sbjct: 396 SIINLLCRFYDIQKGEILIDGIDIRKVRQQDLRKHIGIVLQDVFLFTGDIKSNIRLNNKN 455 Query: 403 XXXXXXXAL-RASCAEAFVHSAPEGIDEPVTERGSTLSAGQRQLISFARAIAHDPAIFVL 461 + + A F+ PEG + VTERGSTLSAGQRQL++FARA+A +P I VL Sbjct: 456 ITDNDIYRVAKYVNAHQFIKKLPEGYNSKVTERGSTLSAGQRQLLAFARALAFNPKILVL 515 Query: 462 DEATANIDTRTEKLIQQAIDNAASGRTTLIIAHRLSTITGADLIIAMKAGRIAESGHPRE 521 DEATANIDT TE+LIQ A++ GRTTL+IAHRLSTI AD II + GRI E G +E Sbjct: 516 DEATANIDTETERLIQDALEKLTKGRTTLVIAHRLSTIQHADKIIVLHKGRIREIGTHQE 575 Query: 522 LL-KRGGYYAKLLQESRDHVYSS 543 LL K+G YY + + +D + S Sbjct: 576 LLQKKGLYYNLYMLQYKDQLSES 598 >ref|NP_951163.1| ABC transporter, ATP-binding/permease protein [Geobacter sulfurreducens PCA] gb|AAR33436.1| ABC transporter, ATP-binding/permease protein [Geobacter sulfurreducens PCA] Length = 592 Score = 355 bits (910), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 191/490 (38%), Positives = 284/490 (57%), Gaps = 9/490 (1%) Query: 51 GQSLIHELRVRVFSIIERLPLPYLDRTSSGRLITRATNDTSEISDLYTDVIISLVKDVLL 110 GQ ++ +LR+ +F+ ++RLP+ + DRT++G L+TR T+D + +++ II++V D+L Sbjct: 101 GQRVMLDLRLELFAHVQRLPVSFFDRTATGGLVTRLTSDVEVLGEMFAAGIITVVGDILF 160 Query: 111 LAGIVYAMLVLSPKLTLVSXXXXXXXXXXXXXXXXXXXXXXXHMKHYIGQINGFIAESIS 170 LAGIV ML L+P L+L++ ++ + +N F+AE+I Sbjct: 161 LAGIVGVMLWLNPPLSLITFSVLPLLVWVAFTFRIRMRKAFREVRARLANLNTFLAETIG 220 Query: 171 GMRVIQIFRAEKEKEQQFLKLNGEYFNTTLIQVRLNSILKPASDMFQSLAIAILVWYSVG 230 GM VIQ+F + + +F +LNG Y + L + ++ L + S+A+ +++WY G Sbjct: 221 GMSVIQLFNRQAGERAEFSRLNGSYRDANLPVITWDASLYALVETLSSVAVGLIIWYGGG 280 Query: 231 RIAGGTLQIGVLYAFTTYIKQFFAPVSDLADKYTSIQSAFVSTXXXXXXXXXXXXXXXPD 290 + G L G L AF YI++FF P+ DL+ KY+ +Q A + D Sbjct: 281 EVLRGALTFGALVAFIQYIEKFFGPIRDLSAKYSIMQGAMAALERIFGLLDTAPDH---D 337 Query: 291 AGLPMQRLNG------RIEFRRVWFSYNGADWVLKDVSFVIEKGQTAAFIGETGAGKTTI 344 AG+ ++ I FR VWF+Y D+VL+ + I +G+T A +GETG GKTT+ Sbjct: 338 AGVSGPAVSAGAPPIETIRFRNVWFAYQEDDYVLRGIDLTIRRGETVALVGETGGGKTTV 397 Query: 345 ISLINGFYKVQKGEILIDGVNVNDIRLDDLRRNISVVLQDVFLFSGTIRXXXXXXXXXXX 404 L++ FY V +G+IL +G +V I L +LRR I VVLQD +LF+GT+ Sbjct: 398 TRLLSRFYDVNRGDILFNGDDVRSIPLSELRRRIGVVLQDPYLFTGTVGFNIHLGDERAR 457 Query: 405 XXXXXALRASCAEAFVHSAPEGIDEPVTERGSTLSAGQRQLISFARAIAHDPAIFVLDEA 464 A R A+ F+ P G DE V ERGS LSAG+RQLISFARA+A DP I VLDEA Sbjct: 458 ARMDDAARLVGADRFIRLLPGGYDEQVRERGSNLSAGERQLISFARAVAFDPEILVLDEA 517 Query: 465 TANIDTRTEKLIQQAIDNAASGRTTLIIAHRLSTITGADLIIAMKAGRIAESGHPRELLK 524 TA+IDT +E+LIQ + +GRT++++AHRLST+ GAD I+ + G E G ELL Sbjct: 518 TASIDTESERLIQDGLAALMAGRTSIVVAHRLSTVQGADRIVVIHRGEKVEEGTHGELLA 577 Query: 525 RGGYYAKLLQ 534 +GG YA+L Q Sbjct: 578 QGGIYARLYQ 587 >ref|ZP_00080324.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Geobacter metallireducens] Length = 602 Score = 343 bits (880), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 186/494 (37%), Positives = 283/494 (57%), Gaps = 11/494 (2%) Query: 51 GQSLIHELRVRVFSIIERLPLPYLDRTSSGRLITRATNDTSEISDLYTDVIISLVKDVLL 110 GQ ++ +LR+ +FS ++RLP+ + DRT +G L+TR T+D + +++ II++V D+L Sbjct: 101 GQRVMFDLRMELFSHVQRLPVAFFDRTPTGSLVTRLTSDVEVLGEMFAAGIITVVGDILF 160 Query: 111 LAGIVYAMLVLSPKLTLVSXXXXXXXXXXXXXXXXXXXXXXXHMKHYIGQINGFIAESIS 170 LAGIV ML ++ KL+LV+ ++ + +N F+AE+I Sbjct: 161 LAGIVGVMLWMNLKLSLVTFAVLPVLIWVAFTFRVRMRKAFREVRARLANLNTFLAETIG 220 Query: 171 GMRVIQIFRAEKEKEQQFLKLNGEYFNTTLIQVRLNSILKPASDMFQSLAIAILVWYSVG 230 GM V+Q+F ++ + ++F +LN Y + L + ++ L + S+A+ +++WY G Sbjct: 221 GMAVVQLFNRQETERREFSRLNAAYRDANLPVITWDASLYALVETLSSIAVGLIIWYGGG 280 Query: 231 RIAGGTLQIGVLYAFTTYIKQFFAPVSDLADKYTSIQSAFVSTXXXXXXXXXXXXXXXPD 290 I G L G L AF Y ++FF P+ DL+ KY+ +Q A ++ P Sbjct: 281 EIVSGALTFGALVAFIQYTEKFFGPIRDLSAKYSIMQGA-MAALERIFNLLDTEKDGYPS 339 Query: 291 AGL----PMQRLNG------RIEFRRVWFSYNGADWVLKDVSFVIEKGQTAAFIGETGAG 340 GL P +R G I F+ VWF+Y ++VL+ + I +G+ A +GETG G Sbjct: 340 PGLRPPSPSRRGAGDEGAVNTIAFKDVWFAYKDEEYVLRGIDLTIRRGEKVALVGETGGG 399 Query: 341 KTTIISLINGFYKVQKGEILIDGVNVNDIRLDDLRRNISVVLQDVFLFSGTIRXXXXXXX 400 KTT+ L++ FY V +G IL DG ++ ++ L DLRR I VVLQ+ +LF+GTI Sbjct: 400 KTTVTRLLSRFYDVSRGSILFDGADIRELPLPDLRRRIGVVLQEPYLFTGTIGFNISLGD 459 Query: 401 XXXXXXXXXALRASCAEAFVHSAPEGIDEPVTERGSTLSAGQRQLISFARAIAHDPAIFV 460 A R A F+ + P+ DE V ERG LSAG+RQLISFARA+A DP I V Sbjct: 460 EGAAARMEEAARLVGAARFIEALPKKYDEEVRERGVNLSAGERQLISFARAVAFDPEILV 519 Query: 461 LDEATANIDTRTEKLIQQAIDNAASGRTTLIIAHRLSTITGADLIIAMKAGRIAESGHPR 520 LDEAT+++D+ +E+LIQ+ + +GRT+L++AHRLST+ AD I+ + G E G R Sbjct: 520 LDEATSSVDSESERLIQEGLRALMAGRTSLVVAHRLSTVQDADRIVVIHRGEKVEEGTHR 579 Query: 521 ELLKRGGYYAKLLQ 534 ELL GG YA+L Q Sbjct: 580 ELLAAGGVYARLYQ 593 >ref|NP_980011.1| ABC transporter, ATP-binding/permease protein [Bacillus cereus ATCC 10987] gb|AAS42619.1| ABC transporter, ATP-binding/permease protein [Bacillus cereus ATCC 10987] Length = 587 Score = 335 bits (858), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 181/482 (37%), Positives = 273/482 (56%), Gaps = 2/482 (0%) Query: 53 SLIHELRVRVFSIIERLPLPYLDRTSSGRLITRATNDTSEISDLYTDVIISLVKDVLLLA 112 ++ ++RV V+ +++L L + DRT G L++R TNDT I D Y V+ + VK+++ LA Sbjct: 93 KIVQDMRVEVYEHVQKLSLSFFDRTPIGTLVSRITNDTEAIKDFYVSVLSTFVKNIVFLA 152 Query: 113 GIVYAMLVLSPKLTLVSXXXXXXXXXXXXXXXXXXXXXXXHMKHYIGQINGFIAESISGM 172 GI+ AM +L+ KL L S +++ + +N + ESI GM Sbjct: 153 GILVAMFLLNVKLALFSLVLIPIMFAIMVLYRRKSAAFYLEVRNQLSVLNAKLNESIQGM 212 Query: 173 RVIQIFRAEKEKEQQFLKLNGEYFNTTLIQVRLNSIL-KPASDMFQSLAIAILVWYSVGR 231 ++Q+FR EK ++F ++N ++++ ++L+++L +PA+D+ +AIA+++ Sbjct: 213 NIVQVFRQEKRMRKEFEEVNNKHYSAGRRTLKLDALLLRPATDLVHIVAIALVLGLFGID 272 Query: 232 IAGGTLQIGVLYAFTTYIKQFFAPVSDLADKYTSIQSAFVSTXXXXXXXXXXXXXXXPDA 291 +++GVLYAF YI +FF PV+++ K + Q A VS+ Sbjct: 273 ALKSPVEVGVLYAFVNYIHRFFQPVNEMMMKLSFFQQALVSSSRVFHLMDEKDLAPVQKG 332 Query: 292 GLPMQRLNGRIEFRRVWFSYNGADWVLKDVSFVIEKGQTAAFIGETGAGKTTIISLINGF 351 Q +NG IEF+ V FSY+G VLK+VSF +++GQT AF+G TG+GK+TI++L+ F Sbjct: 333 DGNPQVINGDIEFKNVTFSYDGKRDVLKNVSFHVKQGQTVAFVGHTGSGKSTIMNLLLRF 392 Query: 352 YKVQKGEILIDGVNVNDIRLDDLRRNISVVLQDVFLFSGTIRXXXXXXXXXXX-XXXXXA 410 Y + G I+IDGV + ++R+ I +VLQD FLF+G ++ A Sbjct: 393 YNINSGNIVIDGVELEKFEEQEIRKKIGLVLQDAFLFAGNVKQNIRMYNEEITDEEVKEA 452 Query: 411 LRASCAEAFVHSAPEGIDEPVTERGSTLSAGQRQLISFARAIAHDPAIFVLDEATANIDT 470 + A F+ PE + V ERG+ S+GQRQLI+FAR IA +P + VLDEATANIDT Sbjct: 453 AQFVQANTFIEKLPEQYETEVVERGAAFSSGQRQLIAFARTIATNPKVLVLDEATANIDT 512 Query: 471 RTEKLIQQAIDNAASGRTTLIIAHRLSTITGADLIIAMKAGRIAESGHPRELLKRGGYYA 530 TE IQ A+ GRTT+ IAHRLSTI AD I M G I E G +ELL G Y Sbjct: 513 ETEDAIQTALQQMRKGRTTIAIAHRLSTIQDADQIFVMHDGEIVERGTHQELLSEQGLYY 572 Query: 531 KL 532 + Sbjct: 573 NM 574 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.138 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 621,910,208 Number of extensions: 21672813 Number of successful extensions: 118428 Number of sequences better than 1.0e-05: 8341 Number of HSP's gapped: 111637 Number of HSP's successfully gapped: 9096 Length of query: 543 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 412 Effective length of database: 401,559,609 Effective search space: 165442558908 Effective search space used: 165442558908 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 128 (53.9 bits)