BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0284.0003.p (578 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_241988.1| BH1122~unknown conserved protein [Bacillus halo... 327 6e-88 ref|NP_603097.1| Two-component sensor kinase yesM [Fusobacterium... 182 2e-44 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 172 2e-41 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 164 4e-39 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 162 1e-38 >ref|NP_241988.1| BH1122~unknown conserved protein [Bacillus halodurans] pir||B83790 hypothetical protein BH1122 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04841.1| BH1122~unknown conserved protein [Bacillus halodurans] Length = 586 Score = 327 bits (837), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 203/568 (35%), Positives = 301/568 (52%), Gaps = 7/568 (1%) Query: 5 FKKYRIDRLFFHSF-AIVLIALIVVTAWTSYSNSSKALVQTTSHYQQQLLDELNNEITTK 63 FK+Y+I +FF SF A +L+A IV+ + SY S +VQ T+ YQ+QLL L+N+I+ Sbjct: 4 FKRYQIRHIFFTSFFAFMLLAFIVIIS-VSYRYSVNEMVQATTEYQEQLLTLLSNDISNY 62 Query: 64 LVMIEQISLSSSRDSELTNFLLNRQDEFERYRRRAGVESALANLTYAIPLIQGIDLYMDN 123 L + IS+ SR S L +D + + + L+N+ Y++P + I++Y+ + Sbjct: 63 LQSYDDISVGLSRQSNFRQALKGSEDPYTYNQLFQSLSRDLSNIVYSVPGLHSIEVYLHS 122 Query: 124 PIPSERQSYIQFRNLADLNKQVGAGCLEKSDFCWSREYNFPSAQGEVPVLSFSRKII-SE 182 P SE Q I + L + + L+ + W E + GE VLS +R + + Sbjct: 123 PPHSEIQQPINYLPLEAVEEMGWTKRLDGKNSVWIGERVSYTMAGEERVLSLARNVFQAR 182 Query: 183 NDYLGVLVVHIKANEIRKLLTGNSDGSNRIMADSEGQQIMKIGDAMDQSDWSRWIDLKSN 242 + GVLV+++ A+ I L S SN ++ D +G+ + + +S + D Sbjct: 183 GEIEGVLVLNVHASTIETWLKQKSQESNLMIIDKQGRFVATSDPQHESVLYSPYFDQYLP 242 Query: 243 KSGYVHIPATDGSRDTLLVYSRMDNSIWTLIEFTSWKQITASSLKLAEWIXXXXXXXXXX 302 + D D L V + N+ WTL + T + ++T S ++A + Sbjct: 243 YQPTMQTGENDKDEDALEVSMPIPNTEWTLKQVTPYSELTEGSRRMAAILVIIGAIMIVV 302 Query: 303 XXXXTHFLSKQFTKPIKNLVTAMRMYSVGGDNVELPVDYENEFGYLFSGYRKQNXXXXXX 362 T+ L+K+FT PI L + Y + ELP DY NEFG LF GY+ Sbjct: 303 ALLVTYSLTKKFTTPIYELKNVLSKYPDQDLSGELPSDYRNEFGELFEGYKGLIRRNNEL 362 Query: 363 XXXXXXXXXQQRKAEIEALQANINPHFLYNMLDQLNWMAIEAGQDELSRILELMGRMFRI 422 +QR+AEI+ALQANINPHFLYN LDQLNWMAIE G +S +LE +G+M RI Sbjct: 363 YRSLHRQYKRQREAEIKALQANINPHFLYNTLDQLNWMAIEKGDRTMSHMLENLGQMLRI 422 Query: 423 GLSNGNSFITIADELLHIECYLEIQQLRWGEGLEYRIEAAPELQELYIPKLTLQPFVENS 482 GLSNG S + + E+ +++ YL+IQ+L+ GE L Y ++ L IPKLTLQPFVEN Sbjct: 423 GLSNGESILPLEKEVEYLKYYLKIQKLKMGERLTYTVDVPVMLYRYLIPKLTLQPFVENC 482 Query: 483 IVHGFNKQRSGYVSIVMERLDDALHIV--IDDNGAGLKQPGLNSQQRHTGGYGIRNVRER 540 +HGF R G +V+ ++D HIV I DNG G + + GGYGIRNV ER Sbjct: 483 FIHGFQDGRDG--EVVIRAMEDQNHIVMTIQDNGIGFQPVTTKRSKLDMGGYGIRNVMER 540 Query: 541 VAGYFGESYGITLKEREEGGTRVEIMLP 568 + YF + + E+GGT V+I++P Sbjct: 541 LDVYFDRYASVHVTGDEQGGTLVKIIIP 568 >ref|NP_603097.1| Two-component sensor kinase yesM [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] gb|AAL94396.1| Two-component sensor kinase yesM [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] Length = 552 Score = 182 bits (461), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 153/566 (27%), Positives = 264/566 (46%), Gaps = 46/566 (8%) Query: 18 FAIVLIALIVVTAWTSYSNSSKALVQTTSHYQQQLLDELNNEITTKLVMIEQISLSSSRD 77 F I + L+++ Y +SS L+Q + + +++ N I + + +S S D Sbjct: 16 FLITNLVLVLLLGSIFYFSSSSLLIQKEISAKTEAIEKSGNYIELYMNKLTTLSQVISHD 75 Query: 78 SELTNFLLNRQDEFERYRRRAGVESALANLTYAIPLIQGIDLYMDNPIPSERQSYIQFRN 137 + ++L N+ DE E+ R +++ L+ P I+ I L R+ N Sbjct: 76 KGVYDYLKNK-DESEKNRILNIIDNTLS----TDPYIKSIILI--------RKDGAVISN 122 Query: 138 LADLNKQVGAGCLEKSDFCWS-----------REYNFPSAQGEVPVLSFSRKIISEN-DY 185 ++N +V + +++ + S R+ NF + V+S SR+I N + Sbjct: 123 EKNVNMEVSSDMMKEEWYVNSLMNPMPVLNPLRKQNFSLDGMDDWVISVSREIADTNGEN 182 Query: 186 LGVLVVHIKANEIRKLLTGNSDGSNR--IMADSEGQQIMKIGDAMDQSDWSRWIDLKSNK 243 LGVL++ +K + + L G N ++ D + + + D S +LK+ + Sbjct: 183 LGVLLIDVKYQALHEYLQNQETGKNSDIVILDEDNRIVYYKEIPYDTSQEKYLKNLKNIE 242 Query: 244 SGYVHIPATDGSRDTLLVYSRMDNSIWTLIEFTSWKQITASSLKLAEWIXXXXXXXXXXX 303 GY + +T+ V + N+ WTLIE + ++I + E I Sbjct: 243 EGY------NRKENTVTVKYPIKNTHWTLIEISYMQEIDSLKNHFFEMIVISCLASLLIT 296 Query: 304 XXXTHFLSKQFTKPIKNLVTAMRMYSVGGDNVELPVDYENEFGYLFSGYRKQNXXXXXXX 363 + ++ TKPIK L M ++ + L D E L + + + Sbjct: 297 VLINISVLRRITKPIKELEQHMNNFNNDLSKINLKGDVSIEILSLQNHFNEM-------- 348 Query: 364 XXXXXXXXQQRKAEIEALQANINPHFLYNMLDQLNWMAIEAGQDELSRILELMGRMFRIG 423 R+ EI AL + INPHFLYN LD + WMA +++ I + + FRI Sbjct: 349 ---IDKIKYLREYEINALYSQINPHFLYNTLDTIIWMAEFQDTEKVISITKALSNFFRIS 405 Query: 424 LSNGNSFITIADELLHIECYLEIQQLRWGEGLEYRIEAAPELQELYIPKLTLQPFVENSI 483 LSNG I + +E+ HI+ YL IQ+ R+ + LEY+I EL+ + +PK+ LQPFVEN+I Sbjct: 406 LSNGKEKIPLKEEINHIKEYLYIQKQRYEDKLEYKISIQEELENIEVPKIILQPFVENAI 465 Query: 484 VHGF-NKQRSGYVSIVMERLDDALHIVIDDNGAGLKQPGLNSQQRHTGGYGIRNVRERVA 542 HG N +G +SI + +++ + ++I+DNG G + + + GG GI+NV +R+ Sbjct: 466 YHGIKNLDTTGIISIYSQIVENKIELIIEDNGIGFEAAKKQALMK-MGGVGIKNVNKRIQ 524 Query: 543 GYFGESYGITLKEREEGGTRVEIMLP 568 Y+G+ YG + + G R+ I LP Sbjct: 525 YYYGKEYGAKIDSSFKTGARIIITLP 550 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 172 bits (435), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 122/422 (28%), Positives = 199/422 (47%), Gaps = 32/422 (7%) Query: 171 PVLSFSRKIISENDYL--GVLVVHIKANEIRKLLTGN--SDGSNRIMADSEGQQIM---- 222 P ++ +R ++ N Y G+LV+ I I K+ + N S +AD G I Sbjct: 176 PKIAMARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIISFKST 235 Query: 223 --KIGDAMDQSDWSRWIDLKSNKSGYVHIPATDGSRDTLLVYSRMDNSIWTLIEFTSWKQ 280 Q+ ++++ K N + S L+ S + S W L+ S K Sbjct: 236 FSGFTPKSAQNILAKYLKDKQN------VVININSSKLLVTSSPIPTSDWRLVSVVSLKN 289 Query: 281 -ITASSLKLAEWIXXXXXXXXXXXXXXTHFLSKQFTKPIKNLVTAMRMYSVGGDNVELPV 339 I + + E+ + + S+ T P++ L +M+ G N+E V Sbjct: 290 AINSIRISFIEFYLRILVFCLLFAFLVSMYFSRALTHPLERLANSMKKVRQG--NLEEKV 347 Query: 340 DYE----NEFGYLFSGYRKQNXXXXXXXXXXXXXXXQQRKAEIEALQANINPHFLYNMLD 395 ++E +E + Y + +R+AE++AL+A INPHFLYN LD Sbjct: 348 EFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPHFLYNTLD 407 Query: 396 QLNWMAIEAGQDELSRILELMGRMFRIGLSNGNSFITIADELLHIECYLEIQQLRWGEGL 455 + W A +A ELS ++ + R+FR+ L+ G FI + E IE YL +Q R+ Sbjct: 408 TIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKF 467 Query: 456 EYRIEAAPELQELYIPKLTLQPFVENSIVHGF-NKQRSGYVSIVMERLDDALHIVIDDNG 514 +Y ++ + E+ + YIPKL LQPFVEN+IVHG N +V ++ E+ + L +I DNG Sbjct: 468 KYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNG 527 Query: 515 AGLKQPGLNSQQRHTG--------GYGIRNVRERVAGYFGESYGITLKEREEGGTRVEIM 566 G+ + L +R GY IRNV ER+ Y+G+ Y + ++ R+ GT + ++ Sbjct: 528 PGMSEETLEKLKRFIESENIEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLI 587 Query: 567 LP 568 LP Sbjct: 588 LP 589 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 164 bits (416), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 105/328 (32%), Positives = 160/328 (48%), Gaps = 17/328 (5%) Query: 260 LVYSRMDNSIWTLIEFTSWKQITASSLKLAEWIXXXXXXXXXXXXXXTHFLSKQFTKPIK 319 L+Y + + WTLI S Q ++ ++ ++FLS ++PI Sbjct: 266 LMYQQSAFTGWTLIGVFSTDQSVEEVQQILFYVVTFVFFVCFVGITASYFLSYTISRPIN 325 Query: 320 NLVTAMRMYSVGGDNVELPVDYENEFGYLFSGYRKQNXXXXXXXXXXXXXXXQQRKAEIE 379 L+ AM+ G + ++E G L + ++R+AE+ Sbjct: 326 QLMLAMQKAESGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLTERQERKKREAELH 385 Query: 380 ALQANINPHFLYNMLDQLNWMAIEAGQDELSRILELMGRMFRIGLSNGNSFITIADELLH 439 +LQANI PHFLYN LD + WMA + +++ ++ + ++FRIGLS G + I + DE+ H Sbjct: 386 SLQANIKPHFLYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEH 445 Query: 440 IECYLEIQQLRWGEGLEYRIEAAPELQELYIPKLTLQPFVENSIVHGFNKQRS-GYVSIV 498 I+ YL+IQ +R+ L Y + ++ L I K+ LQP VEN+I HG ++R G ++I Sbjct: 446 IKNYLQIQSVRYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIYHGIKERRGPGLITIE 505 Query: 499 MERLDDALHIVIDDNGAGLKQPGLN----------------SQQRHTGGYGIRNVRERVA 542 ER +D L I I DNG G+K L QR T GYG+ NV R+ Sbjct: 506 AERENDMLIIRIRDNGKGIKPETLQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLR 565 Query: 543 GYFGESYGITLKEREEGGTRVEIMLPLL 570 FGE YG+ + GT V I P+L Sbjct: 566 LTFGEPYGVKIDSVFNEGTVVTIFHPIL 593 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 162 bits (411), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 91/270 (33%), Positives = 142/270 (52%), Gaps = 7/270 (2%) Query: 310 LSKQFTKPIKNLVTAMRMYSVGGDNVELPVDYENEFGYLFSGYRKQNXXXXXXXXXXXXX 369 +S KPI L + M S G + + +E L + + Sbjct: 302 ISGSIVKPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQV 361 Query: 370 XXQQRKAEIEALQANINPHFLYNMLDQLNWMAIEAGQDELSRILELMGRMFRIGLSNGNS 429 Q+R AE+ LQ+ INPHFLYN LD + W A+E E+ ++ + FRI LS+G Sbjct: 362 EKQKRSAELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKE 421 Query: 430 FITIADELLHIECYLEIQQLRWGEGLEYRIEAAPELQELYIPKLTLQPFVENSIVHGFNK 489 FITI+DE+ H+ YLEIQ++R+ + + Y ++ L + IPKL +QP VENSI HG Sbjct: 422 FITISDEVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKL 481 Query: 490 QR-SGYVSIVMERLDDALHIVIDDNGAGLKQPGLNSQQRH------TGGYGIRNVRERVA 542 Q+ G +++ + D L I + DNG G+ L + +++ T YG+ N+ ER+ Sbjct: 482 QKHKGIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLWESIETNHYGLYNINERLK 541 Query: 543 GYFGESYGITLKEREEGGTRVEIMLPLLTE 572 FG+ Y I +K + GT+V + +PL++E Sbjct: 542 LAFGKKYSIEIKSELKIGTQVLLRIPLISE 571 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 816,098,078 Number of extensions: 32941096 Number of successful extensions: 74900 Number of sequences better than 1.0e-05: 174 Number of HSP's gapped: 74627 Number of HSP's successfully gapped: 174 Length of query: 578 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 447 Effective length of database: 401,559,609 Effective search space: 179497145223 Effective search space used: 179497145223 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)