BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0282.0010.p (218 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00060114.1| COG2197: Response regulator containing a CheY... 94 2e-18 ref|NP_350019.1| Response regulator (CheY-like receiver domain a... 91 1e-17 ref|ZP_00019684.1| hypothetical protein [Chloroflexus aurantiacus] 89 7e-17 ref|NP_607683.1| putative two-component response regulator [Stre... 86 5e-16 ref|NP_801758.1| putative two-component response regulator [Stre... 86 5e-16 >ref|ZP_00060114.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Clostridium thermocellum ATCC 27405] Length = 216 Score = 94.4 bits (233), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 64/205 (31%), Positives = 104/205 (50%), Gaps = 4/205 (1%) Query: 2 MKVWRVIIVGCHPTSMLGTKLILEESKEIEVVGMFSNWSEGVHTVQQQQPDLVLTDYQMP 61 M RV+I H G K ILE K+I VV SN E V ++ QPD+VL D MP Sbjct: 1 MDKIRVVIADDHAMVREGLKQILELEKDIAVVAQASNGEEAVKLAKECQPDVVLMDINMP 60 Query: 62 EGNVEGALVEMKQSSKSTHFIIMTEEEDKELFQPLIELGASGVLSKGASPRQLLQMISGL 121 N A+ ++K + + I++T EDKE +++GA G + K A L++ I + Sbjct: 61 GMNGLQAIEKIKAENLAVKIIVLTIHEDKEYLFKTLQMGAEGYVLKDADSTVLVEAIRSV 120 Query: 122 REG--FL--SIPLEWAQDGFRPVASSRGLDGVLQLTQTEMFIMERIVQGITYDKIALEIE 177 G ++ ++ E ++ R + + LT E+ ++E I QG+ +IA + Sbjct: 121 NRGESYIQSNMTKELVREFNRVTVNEKAKKTENDLTPRELEVLELIAQGLINKEIAKRLF 180 Query: 178 VSRRSIDNYLRKIYVKLEVSTRAQA 202 +S +++ N++ I+ KL VS R QA Sbjct: 181 ISEKTVKNHVSNIFKKLNVSDRTQA 205 >ref|NP_350019.1| Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) [Clostridium acetobutylicum] pir||D97321 response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) [imported] - Clostridium acetobutylicum gb|AAK81359.1| Response regulator (CheY-like receiver domain and HTH-type DNA-binding domain) [Clostridium acetobutylicum] Length = 217 Score = 91.3 bits (225), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 105/206 (50%), Gaps = 2/206 (0%) Query: 2 MKVWRVIIVGCHPTSMLGTKLILEESKEIEVVGMFSNWSEGVHTVQQQQPDLVLTDYQMP 61 M R+++V H G KLI E E EVVG N + + + + +PD++L D MP Sbjct: 1 MSKRRILVVDDHFVVREGLKLIFELEDEYEVVGEAENGEQALLLIDELKPDVILMDLSMP 60 Query: 62 EGNVEGALVEMKQSSKSTHFIIMTEEEDKELFQPLIELGASGVLSKGASPRQLLQMISGL 121 + + L +K+ S II+T + L + + LGA G L K + +L++ + Sbjct: 61 KMSGLDVLKALKEKENSIPIIILTTYNEDNLIKEGLSLGAKGYLLKDTTREELIRTVESA 120 Query: 122 REGFLSIPLEWAQDGFRPVASSRGLDGVLQ--LTQTEMFIMERIVQGITYDKIALEIEVS 179 G L + E ++ F ++ +T+ E+FI++ I +G +IA ++ +S Sbjct: 121 FRGELLLQPEVSKVLFNVKKKESTINTSFNASITERELFILQSIARGCKSKEIAFDMGIS 180 Query: 180 RRSIDNYLRKIYVKLEVSTRAQAIEK 205 R++ +L IY KL+VS+R++A+ K Sbjct: 181 ERTVKAHLTNIYSKLQVSSRSEAVAK 206 >ref|ZP_00019684.1| hypothetical protein [Chloroflexus aurantiacus] Length = 254 Score = 89.0 bits (219), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 69/212 (32%), Positives = 115/212 (54%), Gaps = 16/212 (7%) Query: 6 RVIIVGCHPTSMLGTKLILEESKEIEVVGMFSNWSEGVHTVQQQQPDLVLTDYQMPEGN- 64 +V+I+ HP G + LE + +IEVVG N E + ++ PD+VL D +P N Sbjct: 26 KVLIIDDHPLFRQGIRWSLESAHDIEVVGEAENGQEAIKLTERLFPDVVLVDINLPGLNG 85 Query: 65 VEGALVEMKQSSKSTHFIIMTEEEDKE-LFQPLIELGASGVLSKGASPRQLLQMISGLRE 123 +E A V +K+ T I+++ ED+E LFQ I++GA+ SK SP +L+ MI + Sbjct: 86 LEVARV-IKRREPRTGIIVLSVYEDEEQLFQA-IKVGAAAFTSKDISPEELVHMIREVAR 143 Query: 124 G-------FLSIPLEWAQ--DGFRPVASSRGLDGV---LQLTQTEMFIMERIVQGITYDK 171 G L+ P A+ FR +A++ DG LT E+ I++ I +G++ + Sbjct: 144 GRYLINDAVLAHPNVAARVLHQFRELAATDEEDGASLFAPLTSREIEILDCIARGLSNKE 203 Query: 172 IALEIEVSRRSIDNYLRKIYVKLEVSTRAQAI 203 IA E+ +S +++ N++ I KL+V+ R A+ Sbjct: 204 IASELSISSQTVKNHITSILAKLQVNDRTMAV 235 >ref|NP_607683.1| putative two-component response regulator [Streptococcus pyogenes MGAS8232] ref|NP_665170.1| putative two-component response regulator [Streptococcus pyogenes MGAS315] gb|AAL98182.1| putative two-component response regulator [Streptococcus pyogenes MGAS8232] gb|AAM79973.1| putative two-component response regulator [Streptococcus pyogenes MGAS315] Length = 213 Score = 86.3 bits (212), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 64/203 (31%), Positives = 102/203 (50%), Gaps = 5/203 (2%) Query: 2 MKVWRVIIVGCHPTSMLGTKLILEESKEIEVVGMFSNWSEGVHTVQQQQPDLVLTDYQMP 61 M +VI+V H +G K L +I+VVG SN EGV +PD+++ D MP Sbjct: 1 MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALALKPDVLVMDLVMP 60 Query: 62 E-GNVEGALVEMKQSSKSTHFIIMTEEEDKELFQPLIELGASGVLSKGASPRQLLQMISG 120 E G VE L E+ + K +++T D E P+I+ GA G + K +S ++L I Sbjct: 61 ELGGVEATL-EVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRK 119 Query: 121 LREGFLSIPLEWAQDGFRPVASSRGLDGVLQLTQTEMFIMERIVQGITYDKIALEIEVSR 180 + +G L+I E + + A + D +LT E I+ + +G IA E+ +S Sbjct: 120 VSKGELAIETEVDK---KIKAHDQHPDLHEELTAREYDILHLLAKGYDNQTIADELFISL 176 Query: 181 RSIDNYLRKIYVKLEVSTRAQAI 203 +++ ++ I KLEV R QA+ Sbjct: 177 KTVKTHVSNILAKLEVDDRTQAV 199 >ref|NP_801758.1| putative two-component response regulator [Streptococcus pyogenes SSI-1] dbj|BAC63591.1| putative two-component response regulator [Streptococcus pyogenes SSI-1] Length = 215 Score = 85.9 bits (211), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 64/203 (31%), Positives = 102/203 (50%), Gaps = 5/203 (2%) Query: 2 MKVWRVIIVGCHPTSMLGTKLILEESKEIEVVGMFSNWSEGVHTVQQQQPDLVLTDYQMP 61 M +VI+V H +G K L +I+VVG SN EGV +PD+++ D MP Sbjct: 3 MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDLALALKPDVLVMDLVMP 62 Query: 62 E-GNVEGALVEMKQSSKSTHFIIMTEEEDKELFQPLIELGASGVLSKGASPRQLLQMISG 120 E G VE L E+ + K +++T D E P+I+ GA G + K +S ++L I Sbjct: 63 ELGGVEATL-EVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRK 121 Query: 121 LREGFLSIPLEWAQDGFRPVASSRGLDGVLQLTQTEMFIMERIVQGITYDKIALEIEVSR 180 + +G L+I E + + A + D +LT E I+ + +G IA E+ +S Sbjct: 122 VSKGELAIETEVDK---KIKAHDQHPDLHEELTAREYDILHLLAKGYDNQTIADELFISL 178 Query: 181 RSIDNYLRKIYVKLEVSTRAQAI 203 +++ ++ I KLEV R QA+ Sbjct: 179 KTVKTHVSNILAKLEVDDRTQAV 201 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 293,087,337 Number of extensions: 11158918 Number of successful extensions: 39740 Number of sequences better than 1.0e-05: 558 Number of HSP's gapped: 39842 Number of HSP's successfully gapped: 558 Length of query: 218 Length of database: 757,237,578 Length adjustment: 121 Effective length of query: 97 Effective length of database: 428,710,599 Effective search space: 41584928103 Effective search space used: 41584928103 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 123 (52.0 bits)