BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0271.0006.p (890 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_658615.1| DNA_pol_A, DNA polymerase family A [Bacillus an... 959 0.0 ref|NP_981011.1| DNA polymerase I [Bacillus cereus ATCC 10987] >... 956 0.0 ref|NP_834293.1| DNA polymerase I [Bacillus cereus ATCC 14579] >... 955 0.0 ref|NP_244019.1| DNA polymerase I [Bacillus halodurans] >gi|2528... 947 0.0 ref|NP_390787.1| DNA polymerase I [Bacillus subtilis] >gi|601500... 947 0.0 >ref|NP_658615.1| DNA_pol_A, DNA polymerase family A [Bacillus anthracis A2012] ref|NP_847034.1| DNA polymerase I [Bacillus anthracis str. Ames] gb|AAP28520.1| DNA polymerase I [Bacillus anthracis str. Ames] Length = 877 Score = 959 bits (2480), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/890 (54%), Positives = 627/890 (70%), Gaps = 18/890 (2%) Query: 3 KLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKI 62 K++L+DGNNI YRAFFA+P L N G TNA+YGFT ML+R++EE KPTHM+VAFDAGK Sbjct: 4 KVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKT 63 Query: 63 TFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADE 122 TFRH+ Y +YKGGRQKTPPELSEQFP ++++L VP++E++ YEADDI+G++++EA E Sbjct: 64 TFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASE 123 Query: 123 AGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLM 182 G V ++SGDKD+LQL S++T V + RKG+TEV+ Y + EKY L+P+QIID+KGLM Sbjct: 124 QGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQIIDMKGLM 183 Query: 183 GDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKKL 241 GD SDNIPGVPGVGEKTA+KLL QFG+VE V D + D A+MSK L Sbjct: 184 GDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKDQALMSKDL 243 Query: 242 ATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXX 301 ATI + P+ +DM + G + P L F SLL +L ++ Sbjct: 244 ATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTP-----------EET 292 Query: 302 XXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPFE 361 + DIT E+ + + L SAL VE +N H+A++ G G+ + YF+ + Sbjct: 293 APAELDDITFDIVEEVTEEM--LQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTD 350 Query: 362 L-LKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEA 420 + LKS A ++WL D + K +D RA +AL W GI G D+ +AAYLLDP + Sbjct: 351 IALKSDA---FKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADT 407 Query: 421 NQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELT 480 +++ + + DEEV+GKGAK +PELEI+ H+ARK + + Q +EL Sbjct: 408 DKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELE 467 Query: 481 DTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEF 540 + LF +LE+PL+R+LADME +G+ V+ E L ++G+E ++ + +IY + GTEF Sbjct: 468 KNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEF 527 Query: 541 NLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQST 600 N+NSPKQLG ILF L LPV+KKTKTGYST A+VL+KL +H+ + IL YR + KL ST Sbjct: 528 NINSPKQLGVILFENLNLPVIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNST 587 Query: 601 YVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPG 660 Y+EGLLK + D+ K+HT + Q + TGRLSS PNLQNIPIRLEEGRKIR+ FVPSE G Sbjct: 588 YIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEG 647 Query: 661 WSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAK 720 W + AADYSQIELRVLAHI+ D+ + EAF DMDIHTKTAMDVFGV D+V SNMRR AK Sbjct: 648 WIMYAADYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKDEVTSNMRRQAK 707 Query: 721 AVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTL 780 AVNFGIVYGISDYGLSQNL I+RK A++FIE+Y E F GV+ YMD+IV +A+++GYV TL Sbjct: 708 AVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATL 767 Query: 781 LERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLL 840 L RRRY+PEI ++NFNLRSFAERTAMNTPIQGTAADIIK AM+ M L E GL++R+LL Sbjct: 768 LNRRRYIPEITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLLL 827 Query: 841 QVHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 QVHDEL+FE P++E+E ++ L+PEVM A++L+VPLK + SYG WY+AK Sbjct: 828 QVHDELIFEAPKEEVEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK 877 >ref|NP_981011.1| DNA polymerase I [Bacillus cereus ATCC 10987] gb|AAS43619.1| DNA polymerase I [Bacillus cereus ATCC 10987] Length = 877 Score = 956 bits (2471), Expect = 0.0, Method: Compositional matrix adjust. Identities = 479/890 (53%), Positives = 626/890 (70%), Gaps = 18/890 (2%) Query: 3 KLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKI 62 K++L+DGNNI YRAFFA+P L N G TNA+YGFT ML+R++EE KPTHM+VAFDAGK Sbjct: 4 KVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKT 63 Query: 63 TFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADE 122 TFRH+ Y +YKGGRQKTPPELSEQFP ++++L VP++E++ YEADDI+G++++EA E Sbjct: 64 TFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASE 123 Query: 123 AGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLM 182 G V ++SGDKD+LQL S++T V + RKG+TEV+ Y + EKY L+P+QIID+KGLM Sbjct: 124 QGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQIIDMKGLM 183 Query: 183 GDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKKL 241 GD SDNIPGVPGVGEKTA+KLL QFG+VE V D + + A+MSK L Sbjct: 184 GDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKLKEKLEANKEQALMSKDL 243 Query: 242 ATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXX 301 ATI + P+ +DM + G + P L F SLL +L ++ Sbjct: 244 ATIITDAPITVHVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTP-----------EET 292 Query: 302 XXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPFE 361 + DIT E+ + + L SAL VE +N H+A++ G G+ + YF+ + Sbjct: 293 APAELDDITFDIVEEVTEEM--LQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTD 350 Query: 362 L-LKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEA 420 + LKS A ++WL D + K +D RA +AL W GI G D+ +AAYLLDP + Sbjct: 351 IALKSDA---FKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADT 407 Query: 421 NQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELT 480 +++ + + DEEV+GKGAK +PELEI+ H+ARK + + Q +EL Sbjct: 408 DKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEELE 467 Query: 481 DTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEF 540 + LF +LE+PL+R+LADME +G+ V+ E L ++G+E ++ + +IY + G EF Sbjct: 468 KNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGREF 527 Query: 541 NLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQST 600 N+NSPKQLG ILF L LPV+KKTKTGYST A+VL+KL +H+ + IL YR + KL ST Sbjct: 528 NINSPKQLGVILFENLNLPVIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNST 587 Query: 601 YVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPG 660 Y+EGLLK + D+ K+HT + Q + TGRLSS PNLQNIPIRLEEGRKIR+ FVPSE G Sbjct: 588 YIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEG 647 Query: 661 WSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAK 720 W + AADYSQIELRVLAHI+ D+ + EAF DMDIHTKTAMDVFGV D+V SNMRR AK Sbjct: 648 WIMYAADYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKDEVTSNMRRQAK 707 Query: 721 AVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTL 780 AVNFGIVYGISDYGLSQNL I+RK A++FIE+Y E F GV+ YMD+IV +A+++GYV TL Sbjct: 708 AVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATL 767 Query: 781 LERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLL 840 L RRRY+PEI ++NFNLRSFAERTAMNTPIQGTAADIIK AM+ M L E GL++R+LL Sbjct: 768 LNRRRYIPEITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLLL 827 Query: 841 QVHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 QVHDEL+FE P++E+E ++ L+PEVM A++L+VPLK + SYG WY+AK Sbjct: 828 QVHDELIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK 877 >ref|NP_834293.1| DNA polymerase I [Bacillus cereus ATCC 14579] gb|AAP11494.1| DNA polymerase I [Bacillus cereus ATCC 14579] Length = 891 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 477/890 (53%), Positives = 627/890 (70%), Gaps = 18/890 (2%) Query: 3 KLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKI 62 K++L+DGNNI YRAFFA+P L N G TNA+YGFT ML+R++EE KPTHM+VAFDAGK Sbjct: 18 KVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKT 77 Query: 63 TFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADE 122 TFRH+ Y +YKGGRQKTPPELSEQFP ++++L VP++E++ YEADDI+G++++EA E Sbjct: 78 TFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASE 137 Query: 123 AGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLM 182 G V ++SGDKD+LQL S++T V + RKG+TEV+ Y + EKY L+P+QIID+KGLM Sbjct: 138 QGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALFEKYSLSPKQIIDMKGLM 197 Query: 183 GDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKKL 241 GD SDNIPGVPGVGEKTA+KLL QFG+VE V D + + A+MSK L Sbjct: 198 GDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENLDQVSGKKLKEKLEENKEQALMSKDL 257 Query: 242 ATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXX 301 ATI + P+ +DM + G + P L F SLL +L ++ Sbjct: 258 ATIITDAPITVHVDDMAYKGYEASDVIPMFESLGFTSLLNKLGVTP-----------EET 306 Query: 302 XXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPFE 361 + DIT E+ + + L SAL VE +N H+A++ G G+ + YF+ + Sbjct: 307 APAELDDITFDIVEEVTEEM--LQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTD 364 Query: 362 L-LKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEA 420 + LKS A ++WL D + K +D RA +AL W GI G D+ +AAYLLDP + Sbjct: 365 IALKSDA---FKEWLADGEMRKHTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPADT 421 Query: 421 NQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELT 480 +++ + + DEEV+GKGAK +PEL+++ H+ARK + + Q +EL Sbjct: 422 DKDFCTVAKMKETHAVKSDEEVYGKGAKRAVPELKVVAEHVARKVHVLYDVKQTFVEELK 481 Query: 481 DTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEF 540 + LF +LE+PL+R+LADME +G+ V+ E L ++G+E ++ + +IY + GTEF Sbjct: 482 KNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEF 541 Query: 541 NLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQST 600 N+NSPKQLG ILF L LPV+KKTKTGYST A+VL+KL +H+ + IL YR + KL ST Sbjct: 542 NINSPKQLGVILFENLNLPVIKKTKTGYSTSADVLDKLMNHHEIIPNILHYRQLGKLNST 601 Query: 601 YVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPG 660 Y+EGLLK + D+ K+HT + Q + TGRLSS PNLQNIPIRLEEGRKIR+ FVPSE G Sbjct: 602 YIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEEG 661 Query: 661 WSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAK 720 W + AADYSQIELRVLAHI+ D+ + EAF DMDIHTKTAMDVFGV D+V SNMRR AK Sbjct: 662 WIMYAADYSQIELRVLAHIANDKGLVEAFQHDMDIHTKTAMDVFGVEKDEVTSNMRRQAK 721 Query: 721 AVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTL 780 AVNFGIVYGISDYGLSQNL I+RK A++FIE+Y E F GV+ YM++IV +A+++GYV TL Sbjct: 722 AVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMEDIVKDAKQKGYVATL 781 Query: 781 LERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLL 840 L RRRY+PEI ++NFNLRSFAERTAMNTPIQGTAADIIK AM+ M L E GL++R+LL Sbjct: 782 LNRRRYIPEITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLLL 841 Query: 841 QVHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 QVHDEL+FE P++E+E ++ L+PEVM A++L+VPLK + SYG WY+AK Sbjct: 842 QVHDELIFEAPKEEIEKLEQLVPEVMEHAIELAVPLKVDYSYGPTWYDAK 891 >ref|NP_244019.1| DNA polymerase I [Bacillus halodurans] pir||A84044 DNA polymerase I polA [imported] - Bacillus halodurans (strain C-125) dbj|BAB06872.1| DNA polymerase I [Bacillus halodurans] Length = 876 Score = 947 bits (2447), Expect = 0.0, Method: Compositional matrix adjust. Identities = 478/890 (53%), Positives = 627/890 (70%), Gaps = 18/890 (2%) Query: 3 KLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKI 62 KL+LIDGN+I YRAFFA+P L N G TNAVYGFT MLL+++E+ KPTHM+VAFDAGK Sbjct: 3 KLVLIDGNSIAYRAFFALPLLNNDKGVYTNAVYGFTMMLLKVLEDEKPTHMVVAFDAGKT 62 Query: 63 TFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADE 122 TFRH+ Y+ YK GRQKTPPELSEQFP++++LL + + E++ +EADD+IG+++++A + Sbjct: 63 TFRHDTYDAYKSGRQKTPPELSEQFPLIRELLDAFNIARVEVENFEADDLIGTLAKQASQ 122 Query: 123 AGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLM 182 +V I +GDKD+LQ+ S+H TVAL RKG+T++++Y + I E+Y +TP+QIID+KGLM Sbjct: 123 ENFEVKIFTGDKDLLQIVSDHVTVALTRKGITQIDVYDEKGIEERYGITPEQIIDMKGLM 182 Query: 183 GDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXX-XXXXXXXXXHADSAIMSKKL 241 GD+SDNIPGVPG+GEKTALKLL+++GSVE VL D H D A+MSKKL Sbjct: 183 GDSSDNIPGVPGIGEKTALKLLKEYGSVEKVLESIDEISGKKMKERLEEHRDQALMSKKL 242 Query: 242 ATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXX 301 ATIY E P+ + F +L+F SLL+++ Sbjct: 243 ATIYLEAPVTLDADSFTFGEYDKKEVVKLFKELDFNSLLDKVDADGEGIEKEELQSLNYE 302 Query: 302 XXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPF- 360 + V EA L D +AL VE EN H+ +++GL ++ Y++P Sbjct: 303 T------LREVKEAHLADK-------AALVVEVLDENYHQGDILGLAIAHNNGCYYIPTD 349 Query: 361 ELLKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEA 420 E L+S A L WL+DE+ K +D RA +AL W+ I AG+ D+Q+A+YLLDP+ + Sbjct: 350 EALRSEA---LIQWLKDERKEKWLFDAKRAVVALGWKNIELAGSTFDLQMASYLLDPSTS 406 Query: 421 NQNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELT 480 + D+T + + DE V+GKGAK +IP+ + LG H+ARK+ A+ + + +++L Sbjct: 407 FHEVSDVTKHHRKGHVHEDEAVYGKGAKRRIPDEKELGEHLARKADAIFQLKEHVEEKLK 466 Query: 481 DTDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEF 540 + + GLF +LEMPLS IL ME G+ V+ E L +G++ A++ L I+ + G F Sbjct: 467 ENEQLGLFNELEMPLSVILGRMETTGVKVDVEQLEQMGEDLNARLEELEQTIHELAGVSF 526 Query: 541 NLNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQST 600 N+NSPKQLGEILF KL LPV+KKTKTGYST A+VLEKLA H+ + IL YR + KL ST Sbjct: 527 NINSPKQLGEILFEKLQLPVIKKTKTGYSTSADVLEKLAGQHEIIDHILHYRQLGKLNST 586 Query: 601 YVEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPG 660 Y++GLLK + TGKVHT + Q + TGRLSS PNLQNIPIRLEEGRKIRK FVPSE Sbjct: 587 YIDGLLKVVHKGTGKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRKAFVPSEKD 646 Query: 661 WSILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAK 720 W ILAADYSQIELRVLAH + DE++ EAF EDMD+HTKTAMDVF VS ++V SNMRRSAK Sbjct: 647 WFILAADYSQIELRVLAHFAEDEKLMEAFREDMDVHTKTAMDVFHVSQEEVTSNMRRSAK 706 Query: 721 AVNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTL 780 AVNFGIVYGISDYGLSQNL I+RKEA+ FIE+YF + V+ Y+D ++ EAR++GYVTTL Sbjct: 707 AVNFGIVYGISDYGLSQNLGITRKEAATFIERYFASYPKVKEYLDHVIDEAREKGYVTTL 766 Query: 781 LERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLL 840 L+RRRYLP++ ++NFN RSFAERTAMNTPIQGTAADIIK AMV M + E L+SR+LL Sbjct: 767 LKRRRYLPDLTSRNFNQRSFAERTAMNTPIQGTAADIIKQAMVQMASRMDEEDLQSRLLL 826 Query: 841 QVHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 QVHDEL+FEVP++E+ MK L+ VM A++L VPLK +V+ G WY+AK Sbjct: 827 QVHDELIFEVPKEEVAQMKELVTSVMEQAVELRVPLKVDVACGDTWYDAK 876 >ref|NP_390787.1| DNA polymerase I [Bacillus subtilis] sp|O34996|DPO1_BACSU DNA polymerase I (POL I) pir||E69680 DNA polymerase I polA - Bacillus subtilis gb|AAC00350.1| DNA-polymerase I [Bacillus subtilis] emb|CAB14869.1| DNA polymerase I [Bacillus subtilis subsp. subtilis str. 168] Length = 880 Score = 947 bits (2447), Expect = 0.0, Method: Compositional matrix adjust. Identities = 473/889 (53%), Positives = 625/889 (70%), Gaps = 15/889 (1%) Query: 3 KLILIDGNNIIYRAFFAMPPLTNTAGQQTNAVYGFTTMLLRLIEEHKPTHMIVAFDAGKI 62 KL+L+DGN++ YRAFFA+P L+N G TNAVYGF +L++++E+ KPTHM+VAFDAGK Sbjct: 6 KLVLVDGNSLAYRAFFALPLLSNDKGVHTNAVYGFAMILMKMLEDEKPTHMLVAFDAGKT 65 Query: 63 TFRHEGYEDYKGGRQKTPPELSEQFPMLKDLLRNLGVPQFEIDGYEADDIIGSISREADE 122 TFRH +++YKGGRQKTPPELSEQ P +++LL + ++E++ YEADDIIG++++ A++ Sbjct: 66 TFRHGTFKEYKGGRQKTPPELSEQMPFIRELLDAYQISRYELEQYEADDIIGTLAKSAEK 125 Query: 123 AGRQVMIVSGDKDMLQLASEHTTVALVRKGVTEVEMYGPRQIREKYDLTPQQIIDLKGLM 182 G +V + SGDKD+ QLA++ TTVA+ RKG+T+VE Y P ++EKY LTP+QIID+KGLM Sbjct: 126 DGFEVKVFSGDKDLTQLATDKTTVAITRKGITDVEFYTPEHVKEKYGLTPEQIIDMKGLM 185 Query: 183 GDASDNIPGVPGVGEKTALKLLQQFGSVEGVLAGTDXXXXXXXXXXXXH-ADSAIMSKKL 241 GD+SDNIPGVPGVGEKTA+KLL+QF SVE +L D D A+MSK+L Sbjct: 186 GDSSDNIPGVPGVGEKTAIKLLKQFDSVEKLLESIDEVSGKKLKEKLEEFKDQALMSKEL 245 Query: 242 ATIYREVPLEHAWEDMVFTGIRSDTAGPALAKLEFKSLLERLSLSAYXXXXXXXXXXXXX 301 ATI + P+E + + + G + L F +LLERL + Sbjct: 246 ATIMTDAPIEVSVSGLEYQGFNREQVIAIFKDLGFNTLLERLGEDS----------AEAE 295 Query: 302 XXXXVLDITIVHEAELPDLIAALPGISALHVESNGENPHRAEVIGLGLSSPEQHYFVPFE 361 + DI + ++ I P SA VE G+N H ++G + + YF+P + Sbjct: 296 QDQSLEDINVKTVTDVTSDILVSP--SAFVVEQIGDNYHEEPILGFSIVNETGAYFIPKD 353 Query: 362 LLKSPAAEKLRDWLEDEKAPKSGYDLHRADLALHWQGIAFAGAANDVQLAAYLLDPTEAN 421 + + +E ++W+E+++ K +D RA +AL WQGI GA D LAAY+++P + Sbjct: 354 I--AVESEVFKEWVENDEQKKWVFDSKRAVVALRWQGIELKGAEFDTLLAAYIINPGNSY 411 Query: 422 QNLYDLTAKYGLPRLSPDEEVFGKGAKYKIPELEILGNHIARKSAAVLGIVQKQQQELTD 481 ++ + YGL +S DE V+GKGAK +P ++L H+ RK+ A+ + +K QEL + Sbjct: 412 DDVASVAKDYGLHIVSSDESVYGKGAKRAVPSEDVLSEHLGRKALAIQSLREKLVQELEN 471 Query: 482 TDMTGLFVDLEMPLSRILADMEKQGIAVNKEDLIDLGKEFEAQISRLAADIYAICGTEFN 541 D LF +LEMPL+ IL +ME G+ V+ + L +G+E A++ I+ I G FN Sbjct: 472 NDQLELFEELEMPLALILGEMESTGVKVDVDRLKRMGEELGAKLKEYEEKIHEIAGEPFN 531 Query: 542 LNSPKQLGEILFVKLGLPVVKKTKTGYSTDAEVLEKLAPYHDAVRLILQYRTIAKLQSTY 601 +NSPKQLG ILF K+GLPVVKKTKTGYST A+VLEKLA HD V ILQYR I KLQSTY Sbjct: 532 INSPKQLGVILFEKIGLPVVKKTKTGYSTSADVLEKLADKHDIVDYILQYRQIGKLQSTY 591 Query: 602 VEGLLKEISPDTGKVHTFYRQTIAATGRLSSQFPNLQNIPIRLEEGRKIRKIFVPSEPGW 661 +EGLLK PD+ KVHT + Q + TGRLSS PNLQNIPIRLEEGRKIR+ FVPSE W Sbjct: 592 IEGLLKVTRPDSHKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEKDW 651 Query: 662 SILAADYSQIELRVLAHISGDERMKEAFVEDMDIHTKTAMDVFGVSADQVDSNMRRSAKA 721 I AADYSQIELRVLAHIS DE + EAF DMDIHTKTAMDVF V+ D+V S MRR AKA Sbjct: 652 LIFAADYSQIELRVLAHISKDENLIEAFTNDMDIHTKTAMDVFHVAKDEVTSAMRRQAKA 711 Query: 722 VNFGIVYGISDYGLSQNLNISRKEASQFIEQYFEVFKGVRRYMDEIVVEARKQGYVTTLL 781 VNFGIVYGISDYGLSQNL I+RKEA FI++Y E F+GV+ YM++ V EA+++GYVTTL+ Sbjct: 712 VNFGIVYGISDYGLSQNLGITRKEAGAFIDRYLESFQGVKAYMEDSVQEAKQKGYVTTLM 771 Query: 782 ERRRYLPEINAKNFNLRSFAERTAMNTPIQGTAADIIKLAMVHMDKALHERGLRSRMLLQ 841 RRRY+PE+ ++NFN+RSFAERTAMNTPIQG+AADIIK AM+ M L E+ L++R+LLQ Sbjct: 772 HRRRYIPELTSRNFNIRSFAERTAMNTPIQGSAADIIKKAMIDMAAKLKEKQLKARLLLQ 831 Query: 842 VHDELVFEVPEDELELMKTLLPEVMAGALKLSVPLKAEVSYGSNWYEAK 890 VHDEL+FE P++E+E+++ L+PEVM AL L VPLK + + G +WY+AK Sbjct: 832 VHDELIFEAPKEEIEILEKLVPEVMEHALALDVPLKVDFASGPSWYDAK 880 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.136 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,227,752,948 Number of extensions: 50220224 Number of successful extensions: 130819 Number of sequences better than 1.0e-05: 1689 Number of HSP's gapped: 126927 Number of HSP's successfully gapped: 1895 Length of query: 890 Length of database: 757,237,578 Length adjustment: 135 Effective length of query: 755 Effective length of database: 390,699,213 Effective search space: 294977905815 Effective search space used: 294977905815 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)