BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0265.0015.p (434 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_457032.1| uracil permease (uracil transporter) [Salmonell... 498 e-139 ref|NP_461432.1| uracil transport protein [Salmonella typhimuriu... 497 e-139 ref|NP_289050.1| uracil transport [Escherichia coli O157:H7 EDL9... 497 e-139 ref|NP_754896.1| Uracil permease [Escherichia coli CFT073] >gi|2... 496 e-139 ref|NP_708335.1| uracil transport [Shigella flexneri 2a str. 301... 496 e-139 >ref|NP_457032.1| uracil permease (uracil transporter) [Salmonella enterica subsp. enterica serovar Typhi] ref|NP_804230.1| uracil permease [Salmonella enterica subsp. enterica serovar Typhi Ty2] pir||AG0818 uracil permease (uracil transporter) STY2738 [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) emb|CAD02699.1| uracil permease (uracil transporter) [Salmonella enterica subsp. enterica serovar Typhi] gb|AAO68079.1| uracil permease [Salmonella enterica subsp. enterica serovar Typhi Ty2] Length = 429 Score = 498 bits (1281), Expect = e-139, Method: Compositional matrix adjust. Identities = 262/436 (60%), Positives = 331/436 (75%), Gaps = 13/436 (2%) Query: 2 QREIQVNEKLPWGPGFLLSLQHLFAMFGSTVLVPNLFGVDPGMILLMNGIGTLLYILICR 61 +R I V+E+ P LSLQHLFAMFG+TVLVP LF ++P +LL NGIGTLLY+ IC+ Sbjct: 3 RRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICK 62 Query: 62 GKIPAYLGSSFAFISPVLGVLEKHQGDHQHGYSLALGAFIVTGVIFILVALIVRYAGTGW 121 GKIPAYLGSSFAFISPVL +L GY +ALG FI+ GV+F LV+ IV+ AGTGW Sbjct: 63 GKIPAYLGSSFAFISPVLLLLPL-------GYEVALGGFIMCGVLFCLVSFIVKKAGTGW 115 Query: 122 IDVVFPPAVMGAIVATIGLELVPVAARMSGLIAPEGATDWTPDGKAITLSMVTLGVTVIG 181 +DV+FPPA MGAIVA IGLEL VAA M+GL+ +G + PD K I +SMVTL VTV G Sbjct: 116 LDVMFPPAAMGAIVAVIGLELAGVAAGMAGLLPAQGQS---PDTKTIIISMVTLAVTVFG 172 Query: 182 AVLFRGFPKIIHILIGIVTGYVLAYIMQVVNTDAISSAHFFSHPTIITPSFDWQVIFTII 241 +VLFRGF II ILIG++ GY L++ + VV+T I+ AH+F+ PT TP F+W I TI+ Sbjct: 173 SVLFRGFLAIIPILIGVLAGYALSFALGVVDTTPIAQAHWFALPTFYTPRFEWFAILTIL 232 Query: 242 PVSLVVIVEHIGHLLVTSNIVGKDLTKEPGLDRSLMGNGISTILSGFFGSTPNTTYGENI 301 P +LVVI EH+GHL+VT+NIV KDL ++PGL RS+ NG+STI+SGFFGSTPNTTYGENI Sbjct: 233 PAALVVIAEHVGHLVVTANIVKKDLVRDPGLHRSMFANGLSTIISGFFGSTPNTTYGENI 292 Query: 302 GVMALTKVYSVYVIGGAAVIAILLSFSGTFSSIIANIPQPVMGGVSLLLFGVIAASGLRI 361 GVMA+T+VYS +VIGGAA+ AILLS G ++ I IP PVMGGVSLLL+GVI ASG+R+ Sbjct: 293 GVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQIIPLPVMGGVSLLLYGVIGASGIRV 352 Query: 362 FVEQKVDFSKATNMILATLVLVVGISGISLTIYGVQLKGMALATIVGMVLSLLFKLIEVL 421 +E KVD++KA N+IL +++L++G+SG + I +LKGMALATIVG+ LSL+FKLI +L Sbjct: 353 LIESKVDYNKAQNLILTSVILIIGVSGAKVHIGAAELKGMALATIVGIGLSLIFKLISLL 412 Query: 422 GLSN---EQDSEKSAH 434 E + +S H Sbjct: 413 RPEEVVLEANDAESPH 428 >ref|NP_461432.1| uracil transport protein [Salmonella typhimurium LT2] gb|AAL21391.1| NCS2 family uracil transport protein [Salmonella typhimurium LT2] gb|AAL28077.1| uracil transport enzyme [Salmonella typhimurium] Length = 429 Score = 497 bits (1280), Expect = e-139, Method: Compositional matrix adjust. Identities = 261/436 (59%), Positives = 330/436 (75%), Gaps = 13/436 (2%) Query: 2 QREIQVNEKLPWGPGFLLSLQHLFAMFGSTVLVPNLFGVDPGMILLMNGIGTLLYILICR 61 +R I V+E+ P LSLQHLFAMFG+TVLVP LF ++P +LL NGIGTLLY+ IC+ Sbjct: 3 RRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICK 62 Query: 62 GKIPAYLGSSFAFISPVLGVLEKHQGDHQHGYSLALGAFIVTGVIFILVALIVRYAGTGW 121 GKIPAYLGSSFAFISPVL +L GY +ALG FI+ GV+F LV+ IV+ AGTGW Sbjct: 63 GKIPAYLGSSFAFISPVLLLLPL-------GYEVALGGFIMCGVLFCLVSFIVKKAGTGW 115 Query: 122 IDVVFPPAVMGAIVATIGLELVPVAARMSGLIAPEGATDWTPDGKAITLSMVTLGVTVIG 181 +DV+FPPA MGAIVA IGLEL VAA M+GL+ +G + PD K I +SMVTL VTV G Sbjct: 116 LDVMFPPAAMGAIVAVIGLELAGVAAGMAGLLPAQGQS---PDTKTIIISMVTLAVTVFG 172 Query: 182 AVLFRGFPKIIHILIGIVTGYVLAYIMQVVNTDAISSAHFFSHPTIITPSFDWQVIFTII 241 +VLFRGF II ILIG++ GY L++ + VV+T I+ AH+F+ PT TP F+W I TI+ Sbjct: 173 SVLFRGFLAIIPILIGVLAGYALSFALGVVDTTPIAQAHWFALPTFYTPRFEWFAILTIL 232 Query: 242 PVSLVVIVEHIGHLLVTSNIVGKDLTKEPGLDRSLMGNGISTILSGFFGSTPNTTYGENI 301 P +LVVI EH+GHL+VT+NIV KDL ++PGL RS+ NG+STI+SGFFGSTPNTTYGENI Sbjct: 233 PAALVVIAEHVGHLVVTANIVKKDLVRDPGLHRSMFANGLSTIISGFFGSTPNTTYGENI 292 Query: 302 GVMALTKVYSVYVIGGAAVIAILLSFSGTFSSIIANIPQPVMGGVSLLLFGVIAASGLRI 361 GVMA+T+VYS +VIGGAA+ AILLS G ++ I IP PVMGGVSLLL+GVI ASG+R+ Sbjct: 293 GVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQIIPLPVMGGVSLLLYGVIGASGIRV 352 Query: 362 FVEQKVDFSKATNMILATLVLVVGISGISLTIYGVQLKGMALATIVGMVLSLLFKLIEVL 421 +E KVD++KA N+IL +++L++G+SG + I +LKGMALATIVG+ LSL+FKLI +L Sbjct: 353 LIESKVDYNKAQNLILTSVILIIGVSGAKVHIGAAELKGMALATIVGICLSLIFKLISLL 412 Query: 422 GLSN---EQDSEKSAH 434 E + + H Sbjct: 413 RPEEVVLEANDAEPPH 428 >ref|NP_289050.1| uracil transport [Escherichia coli O157:H7 EDL933] ref|NP_311386.1| uracil transport [Escherichia coli O157:H7] ref|NP_416992.1| UraA [Escherichia coli K12] sp|P33780|URAA_ECOLI Uracil permease (Uracil transporter) pir||A56265 uracil transport protein uraA - Escherichia coli (strain K-12) pir||G91048 uracil transport ECs3359 [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) pir||C85893 uracil transport [imported] - Escherichia coli (strain O157:H7, substrain EDL933) emb|CAA51992.1| uracil permease [Escherichia coli] gb|AAC75550.1| uracil transport [Escherichia coli K12] dbj|BAA16385.1| uracil transport protein uraA [Escherichia coli] gb|AAG57607.1| uracil transport [Escherichia coli O157:H7 EDL933] dbj|BAB36782.1| uracil transport [Escherichia coli O157:H7] Length = 429 Score = 497 bits (1279), Expect = e-139, Method: Compositional matrix adjust. Identities = 259/420 (61%), Positives = 327/420 (77%), Gaps = 10/420 (2%) Query: 2 QREIQVNEKLPWGPGFLLSLQHLFAMFGSTVLVPNLFGVDPGMILLMNGIGTLLYILICR 61 +R I V+E+ P LSLQHLFAMFG+TVLVP LF ++P +LL NGIGTLLY+ IC+ Sbjct: 3 RRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICK 62 Query: 62 GKIPAYLGSSFAFISPVLGVLEKHQGDHQHGYSLALGAFIVTGVIFILVALIVRYAGTGW 121 GKIPAYLGSSFAFISPVL +L GY +ALG FI+ GV+F LV+ IV+ AGTGW Sbjct: 63 GKIPAYLGSSFAFISPVLLLLPL-------GYEVALGGFIMCGVLFCLVSFIVKKAGTGW 115 Query: 122 IDVVFPPAVMGAIVATIGLELVPVAARMSGLIAPEGATDWTPDGKAITLSMVTLGVTVIG 181 +DV+FPPA MGAIVA IGLEL VAA M+GL+ EG T PD K I +S+ TL VTV+G Sbjct: 116 LDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQT---PDSKTIIISITTLAVTVLG 172 Query: 182 AVLFRGFPKIIHILIGIVTGYVLAYIMQVVNTDAISSAHFFSHPTIITPSFDWQVIFTII 241 +VLFRGF II ILIG++ GY L++ M +V+T I +AH+F+ PT+ TP F+W I TI+ Sbjct: 173 SVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTLYTPRFEWFAILTIL 232 Query: 242 PVSLVVIVEHIGHLLVTSNIVGKDLTKEPGLDRSLMGNGISTILSGFFGSTPNTTYGENI 301 P +LVVI EH+GHL+VT+NIV KDL ++PGL RS+ NG+ST++SGFFGSTPNTTYGENI Sbjct: 233 PAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENI 292 Query: 302 GVMALTKVYSVYVIGGAAVIAILLSFSGTFSSIIANIPQPVMGGVSLLLFGVIAASGLRI 361 GVMA+T+VYS +VIGGAA+ AILLS G ++ I IP PVMGGVSLLL+GVI ASG+R+ Sbjct: 293 GVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVMGGVSLLLYGVIGASGIRV 352 Query: 362 FVEQKVDFSKATNMILATLVLVVGISGISLTIYGVQLKGMALATIVGMVLSLLFKLIEVL 421 +E KVD++KA N+IL +++L++G+SG + I +LKGMALATIVG+ LSL+FKLI VL Sbjct: 353 LIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGLSLIFKLISVL 412 >ref|NP_754896.1| Uracil permease [Escherichia coli CFT073] gb|AAN81464.1| Uracil permease [Escherichia coli CFT073] Length = 443 Score = 496 bits (1277), Expect = e-139, Method: Compositional matrix adjust. Identities = 258/420 (61%), Positives = 327/420 (77%), Gaps = 10/420 (2%) Query: 2 QREIQVNEKLPWGPGFLLSLQHLFAMFGSTVLVPNLFGVDPGMILLMNGIGTLLYILICR 61 +R I V+E+ P LSLQHLFAMFG+TVLVP LF ++P +LL NGIGTLLY+ IC+ Sbjct: 17 RRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICK 76 Query: 62 GKIPAYLGSSFAFISPVLGVLEKHQGDHQHGYSLALGAFIVTGVIFILVALIVRYAGTGW 121 GKIPAYLGSSFAFISPVL +L GY +ALG FI+ GV+F LV+ IV+ AGTGW Sbjct: 77 GKIPAYLGSSFAFISPVLLLLPL-------GYEVALGGFIMCGVLFCLVSFIVKKAGTGW 129 Query: 122 IDVVFPPAVMGAIVATIGLELVPVAARMSGLIAPEGATDWTPDGKAITLSMVTLGVTVIG 181 +DV+FPPA MGAIVA IGLEL VAA M+GL+ EG T PD K I +S+ TL VTV+G Sbjct: 130 LDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQT---PDSKTIIISITTLAVTVLG 186 Query: 182 AVLFRGFPKIIHILIGIVTGYVLAYIMQVVNTDAISSAHFFSHPTIITPSFDWQVIFTII 241 +VLFRGF II ILIG++ GY L++ M +V+T I +AH+F+ PT+ TP F+W I TI+ Sbjct: 187 SVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTLYTPRFEWFAILTIL 246 Query: 242 PVSLVVIVEHIGHLLVTSNIVGKDLTKEPGLDRSLMGNGISTILSGFFGSTPNTTYGENI 301 P +LVVI EH+GHL+VT+NIV KDL ++PGL RS+ NG+ST++SGFFGSTPNTTYGENI Sbjct: 247 PAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENI 306 Query: 302 GVMALTKVYSVYVIGGAAVIAILLSFSGTFSSIIANIPQPVMGGVSLLLFGVIAASGLRI 361 GVMA+T+VYS +VIGGAA+ AILLS G ++ I IP PVMGGVSLLL+GVI ASG+R+ Sbjct: 307 GVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVMGGVSLLLYGVIGASGIRV 366 Query: 362 FVEQKVDFSKATNMILATLVLVVGISGISLTIYGVQLKGMALATIVGMVLSLLFKLIEVL 421 +E KVD++KA N+IL +++L++G+SG + I +LKGMALATIVG+ LSL+FKLI +L Sbjct: 367 LIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGLSLIFKLISML 426 >ref|NP_708335.1| uracil transport [Shigella flexneri 2a str. 301] gb|AAN44042.1| uracil transport [Shigella flexneri 2a str. 301] Length = 443 Score = 496 bits (1276), Expect = e-139, Method: Compositional matrix adjust. Identities = 258/420 (61%), Positives = 327/420 (77%), Gaps = 10/420 (2%) Query: 2 QREIQVNEKLPWGPGFLLSLQHLFAMFGSTVLVPNLFGVDPGMILLMNGIGTLLYILICR 61 +R I V+E+ P LSLQHLFAMFG+TVLVP LF ++P +LL NGIGTLLY+ IC+ Sbjct: 17 RRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICK 76 Query: 62 GKIPAYLGSSFAFISPVLGVLEKHQGDHQHGYSLALGAFIVTGVIFILVALIVRYAGTGW 121 GKIPAYLGSSFAFISPVL +L GY +ALG FI+ GV+F LV+ IV+ AGTGW Sbjct: 77 GKIPAYLGSSFAFISPVLLLLPL-------GYEVALGGFIMCGVLFCLVSFIVKKAGTGW 129 Query: 122 IDVVFPPAVMGAIVATIGLELVPVAARMSGLIAPEGATDWTPDGKAITLSMVTLGVTVIG 181 +DV+FPPA MGAIVA IGLEL VAA M+GL+ EG T P+ K I +S+ TL VTV+G Sbjct: 130 LDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQT---PNSKTIIISITTLAVTVLG 186 Query: 182 AVLFRGFPKIIHILIGIVTGYVLAYIMQVVNTDAISSAHFFSHPTIITPSFDWQVIFTII 241 +VLFRGF II ILIG++ GY L++ M +V+T I +AH+F+ PT+ TP F+W I TI+ Sbjct: 187 SVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTLYTPRFEWFAILTIL 246 Query: 242 PVSLVVIVEHIGHLLVTSNIVGKDLTKEPGLDRSLMGNGISTILSGFFGSTPNTTYGENI 301 P +LVVI EH+GHL+VT+NIV KDL ++PGL RS+ NG+ST++SGFFGSTPNTTYGENI Sbjct: 247 PAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENI 306 Query: 302 GVMALTKVYSVYVIGGAAVIAILLSFSGTFSSIIANIPQPVMGGVSLLLFGVIAASGLRI 361 GVMA+T+VYS +VIGGAA+ AILLS G ++ I IP PVMGGVSLLL+GVI ASG+R+ Sbjct: 307 GVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVMGGVSLLLYGVIGASGIRV 366 Query: 362 FVEQKVDFSKATNMILATLVLVVGISGISLTIYGVQLKGMALATIVGMVLSLLFKLIEVL 421 +E KVD++KA N+IL +++L++G+SG + I +LKGMALATIVG+ LSL+FKLI VL Sbjct: 367 LIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGLSLIFKLISVL 426 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.325 0.143 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 626,171,568 Number of extensions: 27317662 Number of successful extensions: 109551 Number of sequences better than 1.0e-05: 485 Number of HSP's gapped: 108704 Number of HSP's successfully gapped: 488 Length of query: 434 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 305 Effective length of database: 406,989,807 Effective search space: 124131891135 Effective search space used: 124131891135 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 127 (53.5 bits)