BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0264.0015.p (1073 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_389435.1| carbamoyl-phosphate synthetase (catalytic subun... 1425 0.0 ref|NP_657856.1| CPSase_L_D2, Carbamoyl-phosphate synthase L cha... 1422 0.0 ref|NP_833606.1| Carbamoyl-phosphate synthase large chain [Bacil... 1420 0.0 ref|NP_980226.1| carbamoyl-phosphate synthase, large subunit [Ba... 1420 0.0 sp|P46537|CARB_BACCL Carbamoyl-phosphate synthase, pyrimidine-sp... 1416 0.0 >ref|NP_389435.1| carbamoyl-phosphate synthetase (catalytic subunit) [Bacillus subtilis] sp|P25994|CARB_BACSU Carbamoyl-phosphate synthase, pyrimidine-specific, large chain (Carbamoyl-phosphate synthetase ammonia chain) pir||F39845 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5), pyrimidine-repressible, large chain pyrAB - Bacillus subtilis gb|AAA21270.1| carbamyl phosphate synthetase [Bacillus subtilis] emb|CAB13426.1| carbamoyl-phosphate synthetase (catalytic subunit) [Bacillus subtilis subsp. subtilis str. 168] Length = 1071 Score = 1425 bits (3690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 693/1069 (64%), Positives = 841/1069 (78%), Gaps = 9/1069 (0%) Query: 1 MPKNEKLKKILVIGSGPIVIGQAAEFDYAGTQACQALKEEGVEVVLINSNPATIMTDTNM 60 MPK + KILVIGSGPI+IGQAAEFDYAGTQAC ALKEEG EV+L+NSNPATIMTDT M Sbjct: 1 MPKRVDINKILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEVILVNSNPATIMTDTEM 60 Query: 61 ADKVYIEPITLEFVTGIIRQERPDXXXXXXXXXXXXNMAVELARAGVLEQENVKLLGTQL 120 AD+VYIEP+T EF+T IIR+ERPD N+AVEL+ GVL + V++LGT+L Sbjct: 61 ADRVYIEPLTPEFLTRIIRKERPDAILPTLGGQTGLNLAVELSERGVLAECGVEVLGTKL 120 Query: 121 GSIEKAEDRDLFRELMRELEQPVPESTIITSVEEAMGFAAGIGYPLIVRPAYTLGGTGGG 180 +I++AEDRDLFR LM EL +PVPES II S+EEA F + IG+P+IVRPAYTLGGTGGG Sbjct: 121 SAIQQAEDRDLFRTLMNELNEPVPESEIIHSLEEAEKFVSQIGFPVIVRPAYTLGGTGGG 180 Query: 181 ICDNEEELRETVKAGIRYSPIGQCLVEKSIAGMKEVEYEVMRDANDNCIVVCNMENFDPV 240 IC NE EL+E V+ G++ SP+ QCL+EKSIAG KE+EYEVMRD+ D+ IVVCNMEN DPV Sbjct: 181 ICSNETELKEIVENGLKLSPVHQCLLEKSIAGYKEIEYEVMRDSQDHAIVVCNMENIDPV 240 Query: 241 GVHTGDSIVVAPSQTLSDREYQMLRSASLKIIRALNIEGGCNVQFALDPQSYQYYVIEVN 300 G+HTGDSIVVAPSQTLSDREYQ+LR+ SLK+IRAL IEGGCNVQ ALDP S+QYY+IEVN Sbjct: 241 GIHTGDSIVVAPSQTLSDREYQLLRNVSLKLIRALGIEGGCNVQLALDPDSFQYYIIEVN 300 Query: 301 PRVSRSSALASKATGYPIAKMAAKIALGYTLDEIVNPVTGQTYACFEPTLDYIVSKIPRW 360 PRVSRSSALASKATGYPIAK+AAKIA+G +LDE++NPVTG+TYA FEP LDY+VSKIPRW Sbjct: 301 PRVSRSSALASKATGYPIAKLAAKIAVGLSLDEMMNPVTGKTYAAFEPALDYVVSKIPRW 360 Query: 361 PFDKFIYANRKLGTQMKATGEVMAIGRTFEESIHKAIRSLEIGIHRFKLPGAEQLEDSVL 420 PFDKF ANRKLGTQMKATGEVMAIGRT EES+ KA+RSLE ++ +L A + D +L Sbjct: 361 PFDKFESANRKLGTQMKATGEVMAIGRTLEESLLKAVRSLEADVYHLELKDAADISDELL 420 Query: 421 RTRLAKADDERLFLIAEAFRRGYGLQEIQDITSVDWWFLSKIEGLVNFEEVIRSEATLSP 480 R+ KA DERLF +AEA+RRGY ++++ + +++D +FL K+ G+V FE+ +++ A Sbjct: 421 EKRIKKAGDERLFYLAEAYRRGYTVEDLHEFSAIDVFFLHKLFGIVQFEKELKANAG-DT 479 Query: 481 ETLYQAKRKGFTDRAIAEIRAEGRPGLEQTKESEVRVLRLQQGLVPVFKMVDTCAAEFXX 540 + L +AK GF+D+ I+ + KESE+ LR Q G+ PVFKMVDTCAAEF Sbjct: 480 DVLRRAKELGFSDQYISREW--------KMKESELYSLRKQAGIAPVFKMVDTCAAEFES 531 Query: 541 XXXXXXXXXXXXXXVIHSDKQKVIVLGSGPIRIGQGIEFDYSTVHAVWAIQKAGYEAVII 600 + +DK+ V+VLGSGPIRIGQG+EFDY+TVH+VWAI++AGYEA+I+ Sbjct: 532 ETPYFYSTYEEENESVVTDKKSVMVLGSGPIRIGQGVEFDYATVHSVWAIKQAGYEAIIV 591 Query: 601 NNNPETVSTDFNTSDRLYFEPLFFEDVMNVIAQENPIGVIVQFGGQTXXXXXXXXXXXGV 660 NNNPETVSTDF+ SD+LYFEPL EDVM++I E P+GV+VQFGGQT GV Sbjct: 592 NNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEQPMGVVVQFGGQTAINLADELSARGV 651 Query: 661 NILGTSLDSIDEAEDRKKFEALLARLDIAQPKGKTVINIDEAVETAQSLGYPVLVRPSYV 720 ILGTSL+ +D AEDR KFE L L + QP GKT ++++AV A +GYPVLVRPSYV Sbjct: 652 KILGTSLEDLDRAEDRDKFEQALGELGVPQPLGKTATSVNQAVSIASDIGYPVLVRPSYV 711 Query: 721 LGGRAMEIVYNDTELLSYMAEAVKVNPEHPVLIDRYMLGKEVEVDAICDGETVVIPGIME 780 LGGRAMEIVY++ ELL YM AVK+NP+HPVLIDRY+ GKE+EVDA+ DGETVVIPGIME Sbjct: 712 LGGRAMEIVYHEEELLHYMKNAVKINPQHPVLIDRYLTGKEIEVDAVSDGETVVIPGIME 771 Query: 781 HVERAGVHSGDSIAVYPPQYLDEGLKQKIADITIKIAKELKTVGLVNIQFVIYQNEVYVI 840 H+ERAGVHSGDSIAVYPPQ L E +K+KI TI +AK L VGL+NIQFV+ Q EVYV+ Sbjct: 772 HIERAGVHSGDSIAVYPPQSLTEDIKKKIEQYTIALAKGLNIVGLLNIQFVLSQGEVYVL 831 Query: 841 EVNPRSSRTVPFLSKVTGIPMAHLATKTILGGKLKEEGYTEGLWPESDYVSVKVPVFSFA 900 EVNPRSSRTVPFLSK+TGIPMA+LATK ILG KL GYTEGL PE V VK PVFSFA Sbjct: 832 EVNPRSSRTVPFLSKITGIPMANLATKIILGQKLAAFGYTEGLQPEQQGVFVKAPVFSFA 891 Query: 901 KLRRVEPTLGPEMKSTGEVMGRDKLYAKALYKGLIGAGMKIPTTGAIIVTVADKDKAEAV 960 KLRRV+ TLGPEMKSTGEVMG+D KALYK LI +G++IP G++++TVADKDK E + Sbjct: 892 KLRRVDITLGPEMKSTGEVMGKDSTLEKALYKALIASGIQIPNYGSVLLTVADKDKEEGL 951 Query: 961 ELMKGFHAMGYKIIATGGTALALEQAGLNVMNVNKLDEGEPTILDLIRSGQANFVFNTLT 1020 + K FHA+GY I+AT GTA L++A + V K+ + P +LD+IR+G+A FV NTLT Sbjct: 952 AIAKRFHAIGYNILATEGTAGYLKEASIPAKVVGKIGQDGPNLLDVIRNGEAQFVINTLT 1011 Query: 1021 KGKTPERDGFRIRREAVENGVVCMTSLDTVTALLRMLQTINFSSQSMPA 1069 KGK P RDGFRIRRE+VENGV C+TSLDT A+LR+L+++ F + MPA Sbjct: 1012 KGKQPARDGFRIRRESVENGVACLTSLDTAEAILRVLESMTFRADQMPA 1060 >ref|NP_657856.1| CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain [Bacillus anthracis A2012] ref|NP_846266.1| carbamoyl-phosphate synthase, large subunit [Bacillus anthracis str. Ames] gb|AAP27752.1| carbamoyl-phosphate synthase, large subunit [Bacillus anthracis str. Ames] Length = 1072 Score = 1422 bits (3681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 692/1067 (64%), Positives = 835/1067 (78%), Gaps = 9/1067 (0%) Query: 1 MPKNEKLKKILVIGSGPIVIGQAAEFDYAGTQACQALKEEGVEVVLINSNPATIMTDTNM 60 MPK + ILVIGSGPIVIGQAAEFDY+GTQACQ+LKEEG +V+L+NSNPATIMTDT Sbjct: 1 MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTAT 60 Query: 61 ADKVYIEPITLEFVTGIIRQERPDXXXXXXXXXXXXNMAVELARAGVLEQENVKLLGTQL 120 ADKVYIEP+TLEFV+ IIR+ERPD NMAVELA++GVLE+ V++LGT+L Sbjct: 61 ADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKL 120 Query: 121 GSIEKAEDRDLFRELMRELEQPVPESTIITSVEEAMGFAAGIGYPLIVRPAYTLGGTGGG 180 +IE+AEDRDLFR LM+EL +P P S II +++EA GF IGYP+IVRPA+TLGGTGGG Sbjct: 121 SAIEQAEDRDLFRTLMQELNEPTPPSEIIHNLDEAYGFVNEIGYPVIVRPAFTLGGTGGG 180 Query: 181 ICDNEEELRETVKAGIRYSPIGQCLVEKSIAGMKEVEYEVMRDANDNCIVVCNMENFDPV 240 IC NEEEL E V +G+++SP+ QCL+EKSIAG KE+EYEVMRD+NDN IVVCNMEN DPV Sbjct: 181 ICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPV 240 Query: 241 GVHTGDSIVVAPSQTLSDREYQMLRSASLKIIRALNIEGGCNVQFALDPQSYQYYVIEVN 300 GVHTGDSIVVAPSQTLSDREYQMLR+ SL+IIRAL IEGGCNVQ ALDP S+QYYVIEVN Sbjct: 241 GVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVN 300 Query: 301 PRVSRSSALASKATGYPIAKMAAKIALGYTLDEIVNPVTGQTYACFEPTLDYIVSKIPRW 360 PRVSRSSALASKATGYPIAK+AAKIA+G TLDEIVNPVT +TYACFEP LDY+VSKIPRW Sbjct: 301 PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRW 360 Query: 361 PFDKFIYANRKLGTQMKATGEVMAIGRTFEESIHKAIRSLEIGIHRFKLPGAEQLEDSVL 420 PFDKF ANR LGTQMKATGEVM+IGR EES+ KA+RSLE+GI+ +L ++L+ + Sbjct: 361 PFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETM 420 Query: 421 RTRLAKADDERLFLIAEAFRRGYGLQEIQDITSVDWWFLSKIEGLVNFEEVIRSEATLSP 480 + R+ KADDERLF++AEA R+G +EI + +D++FL K+E +VN E +++ + Sbjct: 421 KKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVG-NM 479 Query: 481 ETLYQAKRKGFTDRAIAEIRAEGRPGLEQTKESEVRVLRLQQGLVPVFKMVDTCAAEFXX 540 E L AK GF+D IA E E+ +R + + PVFKMVDTCAAEF Sbjct: 480 EVLQTAKEMGFSDHYIA--------AAWNKTEREIYDMRKENNMTPVFKMVDTCAAEFES 531 Query: 541 XXXXXXXXXXXXXXVIHSDKQKVIVLGSGPIRIGQGIEFDYSTVHAVWAIQKAGYEAVII 600 +I +D++ V+VLGSGPIRIGQG+EFDY+TVH+VWAI++AGYEA+II Sbjct: 532 ATPYYYSTYADENELIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIII 591 Query: 601 NNNPETVSTDFNTSDRLYFEPLFFEDVMNVIAQENPIGVIVQFGGQTXXXXXXXXXXXGV 660 NNNPETVSTDF+ SD+LYFEPL EDVM++I E P GVIVQFGGQT GV Sbjct: 592 NNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGV 651 Query: 661 NILGTSLDSIDEAEDRKKFEALLARLDIAQPKGKTVINIDEAVETAQSLGYPVLVRPSYV 720 ILGTSL+ +D AEDR KFEA L +L I QP GKT +++AV A+ +GYPVLVRPSYV Sbjct: 652 KILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYV 711 Query: 721 LGGRAMEIVYNDTELLSYMAEAVKVNPEHPVLIDRYMLGKEVEVDAICDGETVVIPGIME 780 LGGRAMEIVY ELL YM AVKV+ +HPVLIDRYM+GKE+EVDAI DGE V IPGIME Sbjct: 712 LGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIME 771 Query: 781 HVERAGVHSGDSIAVYPPQYLDEGLKQKIADITIKIAKELKTVGLVNIQFVIYQNEVYVI 840 H+ERAGVHSGDSI VYPPQ L E LK++I + TI + K L VGL+NIQFV+++++VYVI Sbjct: 772 HIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFKDQVYVI 831 Query: 841 EVNPRSSRTVPFLSKVTGIPMAHLATKTILGGKLKEEGYTEGLWPESDYVSVKVPVFSFA 900 EVNPR+SRTVPFLSK+TG+PMA++ATK ILG L E+GY G PE V VK PVFSFA Sbjct: 832 EVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFA 891 Query: 901 KLRRVEPTLGPEMKSTGEVMGRDKLYAKALYKGLIGAGMKIPTTGAIIVTVADKDKAEAV 960 KLR V+ TLGPEMKSTGEVMG+D KALYKGL+ +G+ IPT G++I+TVADKDK EA+ Sbjct: 892 KLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAM 951 Query: 961 ELMKGFHAMGYKIIATGGTALALEQAGLNVMNVNKLDEGEPTILDLIRSGQANFVFNTLT 1020 E+ K FH +GY ++AT GTA +L + + V VNK+D + +LD+IR G+A FV NTLT Sbjct: 952 EIAKRFHEIGYNLLATAGTAQSLTEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLT 1011 Query: 1021 KGKTPERDGFRIRREAVENGVVCMTSLDTVTALLRMLQTINFSSQSM 1067 KGK P RDGFRIRRE+VENGV C+TSLDT A+LR+L+++ FS+ SM Sbjct: 1012 KGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSM 1058 >ref|NP_833606.1| Carbamoyl-phosphate synthase large chain [Bacillus cereus ATCC 14579] gb|AAP10807.1| Carbamoyl-phosphate synthase large chain [Bacillus cereus ATCC 14579] Length = 1072 Score = 1420 bits (3677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 691/1067 (64%), Positives = 836/1067 (78%), Gaps = 9/1067 (0%) Query: 1 MPKNEKLKKILVIGSGPIVIGQAAEFDYAGTQACQALKEEGVEVVLINSNPATIMTDTNM 60 MPK + ILVIGSGPIVIGQAAEFDY+GTQACQ+LKEEG +V+L+NSNPATIMTDT Sbjct: 1 MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTAT 60 Query: 61 ADKVYIEPITLEFVTGIIRQERPDXXXXXXXXXXXXNMAVELARAGVLEQENVKLLGTQL 120 ADKVYIEP+TLEFV+ IIR+ERPD NMAVELA++GVL++ V++LGT+L Sbjct: 61 ADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLDECGVEILGTKL 120 Query: 121 GSIEKAEDRDLFRELMRELEQPVPESTIITSVEEAMGFAAGIGYPLIVRPAYTLGGTGGG 180 +IE+AEDRDLFR LM++L +P P S II +++EA GF IGYP+IVRPA+TLGGTGGG Sbjct: 121 SAIEQAEDRDLFRTLMQDLNEPTPPSEIIHNLDEAYGFVNEIGYPVIVRPAFTLGGTGGG 180 Query: 181 ICDNEEELRETVKAGIRYSPIGQCLVEKSIAGMKEVEYEVMRDANDNCIVVCNMENFDPV 240 IC NEEEL E V +G+++SP+ QCL+EKSIAG KE+EYEVMRD+NDN IVVCNMEN DPV Sbjct: 181 ICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPV 240 Query: 241 GVHTGDSIVVAPSQTLSDREYQMLRSASLKIIRALNIEGGCNVQFALDPQSYQYYVIEVN 300 GVHTGDSIVVAPSQTLSDREYQMLR+ SL+IIRAL IEGGCNVQ ALDP S+QYYVIEVN Sbjct: 241 GVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVN 300 Query: 301 PRVSRSSALASKATGYPIAKMAAKIALGYTLDEIVNPVTGQTYACFEPTLDYIVSKIPRW 360 PRVSRSSALASKATGYPIAK+AAKIA+G TLDEIVNPVT +TYACFEP LDY+VSKIPRW Sbjct: 301 PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRW 360 Query: 361 PFDKFIYANRKLGTQMKATGEVMAIGRTFEESIHKAIRSLEIGIHRFKLPGAEQLEDSVL 420 PFDKF ANR LGTQMKATGEVM+IGR EES+ KA+RSLE+GI+ +L ++L+ + Sbjct: 361 PFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETM 420 Query: 421 RTRLAKADDERLFLIAEAFRRGYGLQEIQDITSVDWWFLSKIEGLVNFEEVIRSEATLSP 480 + R+ KADDERLF++AEA R+G +EI + +D++FL K+E +VN E +++ + Sbjct: 421 KKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVG-NM 479 Query: 481 ETLYQAKRKGFTDRAIAEIRAEGRPGLEQTKESEVRVLRLQQGLVPVFKMVDTCAAEFXX 540 E L AK GF+D IA E E+ +R + ++PVFKMVDTCAAEF Sbjct: 480 EVLQTAKEMGFSDHYIA--------AAWNKTEREIYDMRKENNMMPVFKMVDTCAAEFES 531 Query: 541 XXXXXXXXXXXXXXVIHSDKQKVIVLGSGPIRIGQGIEFDYSTVHAVWAIQKAGYEAVII 600 I +D++ V+VLGSGPIRIGQG+EFDY+TVH+VWAI++AGYEA+II Sbjct: 532 ATPYYYSTYADENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIII 591 Query: 601 NNNPETVSTDFNTSDRLYFEPLFFEDVMNVIAQENPIGVIVQFGGQTXXXXXXXXXXXGV 660 NNNPETVSTDF+ SD+LYFEPL EDVM++I E P GVIVQFGGQT GV Sbjct: 592 NNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGV 651 Query: 661 NILGTSLDSIDEAEDRKKFEALLARLDIAQPKGKTVINIDEAVETAQSLGYPVLVRPSYV 720 ILGTSL+ +D AEDR KFEA L +L I QP GKT +++AV A+ +GYPVLVRPSYV Sbjct: 652 KILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYV 711 Query: 721 LGGRAMEIVYNDTELLSYMAEAVKVNPEHPVLIDRYMLGKEVEVDAICDGETVVIPGIME 780 LGGRAMEIVY ELL YM AVKV+ +HPVLIDRYM+GKE+EVDAI DGE V IPGIME Sbjct: 712 LGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIME 771 Query: 781 HVERAGVHSGDSIAVYPPQYLDEGLKQKIADITIKIAKELKTVGLVNIQFVIYQNEVYVI 840 H+ERAGVHSGDSI VYPPQ L E LK++I + TI + K L VGL+NIQFV+++++VYVI Sbjct: 772 HIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFKDQVYVI 831 Query: 841 EVNPRSSRTVPFLSKVTGIPMAHLATKTILGGKLKEEGYTEGLWPESDYVSVKVPVFSFA 900 EVNPR+SRTVPFLSK+TG+PMA++ATK ILG L E+GY G PE V VK PVFSFA Sbjct: 832 EVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFA 891 Query: 901 KLRRVEPTLGPEMKSTGEVMGRDKLYAKALYKGLIGAGMKIPTTGAIIVTVADKDKAEAV 960 KLR V+ TLGPEMKSTGEVMG+D KALYKGL+ +G+ IPT G++I+TVADKDK EA+ Sbjct: 892 KLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAM 951 Query: 961 ELMKGFHAMGYKIIATGGTALALEQAGLNVMNVNKLDEGEPTILDLIRSGQANFVFNTLT 1020 E+ K FH +GY ++AT GTA +LE+ + V VNK+D + +LD+IR G+A FV NTLT Sbjct: 952 EIAKRFHEIGYNLLATAGTAQSLEEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLT 1011 Query: 1021 KGKTPERDGFRIRREAVENGVVCMTSLDTVTALLRMLQTINFSSQSM 1067 KGK P RDGFRIRRE+VENGV C+TSLDT A+LR+L+++ FS+ SM Sbjct: 1012 KGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSM 1058 >ref|NP_980226.1| carbamoyl-phosphate synthase, large subunit [Bacillus cereus ATCC 10987] gb|AAS42834.1| carbamoyl-phosphate synthase, large subunit [Bacillus cereus ATCC 10987] Length = 1072 Score = 1420 bits (3675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 691/1067 (64%), Positives = 833/1067 (78%), Gaps = 9/1067 (0%) Query: 1 MPKNEKLKKILVIGSGPIVIGQAAEFDYAGTQACQALKEEGVEVVLINSNPATIMTDTNM 60 MPK + ILVIGSGPIVIGQAAEFDY+GTQACQ+LKEEG +V+L+NSNPATIMTDT Sbjct: 1 MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTAT 60 Query: 61 ADKVYIEPITLEFVTGIIRQERPDXXXXXXXXXXXXNMAVELARAGVLEQENVKLLGTQL 120 ADKVYIEP+TLEFV+ IIR+ERPD NMAVELA++GVLE+ V++LGT+L Sbjct: 61 ADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKL 120 Query: 121 GSIEKAEDRDLFRELMRELEQPVPESTIITSVEEAMGFAAGIGYPLIVRPAYTLGGTGGG 180 +IE+AEDRDLFR LM++L +P P S II +++EA F IGYP+IVRPA+TLGGTGGG Sbjct: 121 SAIEQAEDRDLFRTLMQDLNEPTPPSEIIHNLDEAYSFVNEIGYPVIVRPAFTLGGTGGG 180 Query: 181 ICDNEEELRETVKAGIRYSPIGQCLVEKSIAGMKEVEYEVMRDANDNCIVVCNMENFDPV 240 IC NEEEL E V +G+++SP+ QCL+EKSIAG KE+EYEVMRD+NDN IVVCNMEN DPV Sbjct: 181 ICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPV 240 Query: 241 GVHTGDSIVVAPSQTLSDREYQMLRSASLKIIRALNIEGGCNVQFALDPQSYQYYVIEVN 300 GVHTGDSIVVAPSQTLSDREYQMLR+ SL+IIRAL IEGGCNVQ ALDP S+QYYVIEVN Sbjct: 241 GVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVN 300 Query: 301 PRVSRSSALASKATGYPIAKMAAKIALGYTLDEIVNPVTGQTYACFEPTLDYIVSKIPRW 360 PRVSRSSALASKATGYPIAK+AAKIA+G TLDEIVNPVT +TYACFEP LDY+VSKIPRW Sbjct: 301 PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRW 360 Query: 361 PFDKFIYANRKLGTQMKATGEVMAIGRTFEESIHKAIRSLEIGIHRFKLPGAEQLEDSVL 420 PFDKF ANR LGTQMKATGEVM+IGR EES+ KA+RSLE+GI+ +L ++L+ + Sbjct: 361 PFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETM 420 Query: 421 RTRLAKADDERLFLIAEAFRRGYGLQEIQDITSVDWWFLSKIEGLVNFEEVIRSEATLSP 480 + R+ KADDERLF++AEA R+G +EI + +D++FL K+E +VN E +++ + Sbjct: 421 KKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVG-NM 479 Query: 481 ETLYQAKRKGFTDRAIAEIRAEGRPGLEQTKESEVRVLRLQQGLVPVFKMVDTCAAEFXX 540 E L AK GF+D IA E E+ +R + + PVFKMVDTCAAEF Sbjct: 480 EVLQTAKEMGFSDHYIA--------AAWNKTEREIYDMRKENNMTPVFKMVDTCAAEFES 531 Query: 541 XXXXXXXXXXXXXXVIHSDKQKVIVLGSGPIRIGQGIEFDYSTVHAVWAIQKAGYEAVII 600 I +D++ V+VLGSGPIRIGQG+EFDY+TVH+VWAI++AGYEA+II Sbjct: 532 ATPYYYSTYAEENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIII 591 Query: 601 NNNPETVSTDFNTSDRLYFEPLFFEDVMNVIAQENPIGVIVQFGGQTXXXXXXXXXXXGV 660 NNNPETVSTDF+ SD+LYFEPL EDVM++I E P GVIVQFGGQT GV Sbjct: 592 NNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGV 651 Query: 661 NILGTSLDSIDEAEDRKKFEALLARLDIAQPKGKTVINIDEAVETAQSLGYPVLVRPSYV 720 ILGTSL+ +D AEDR KFEA L +L I QP GKT +++AV A+ +GYPVLVRPSYV Sbjct: 652 KILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYV 711 Query: 721 LGGRAMEIVYNDTELLSYMAEAVKVNPEHPVLIDRYMLGKEVEVDAICDGETVVIPGIME 780 LGGRAMEIVY ELL YM AVKV+ +HPVLIDRYM+GKE+EVDAI DGE V IPGIME Sbjct: 712 LGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIME 771 Query: 781 HVERAGVHSGDSIAVYPPQYLDEGLKQKIADITIKIAKELKTVGLVNIQFVIYQNEVYVI 840 H+ERAGVHSGDSI VYPPQ L E LK++I + TI + K L VGL+NIQFV+++N+VYVI Sbjct: 772 HIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFENQVYVI 831 Query: 841 EVNPRSSRTVPFLSKVTGIPMAHLATKTILGGKLKEEGYTEGLWPESDYVSVKVPVFSFA 900 EVNPR+SRTVPFLSK+TG+PMA++ATK ILG L E+GY G PE V VK PVFSFA Sbjct: 832 EVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFA 891 Query: 901 KLRRVEPTLGPEMKSTGEVMGRDKLYAKALYKGLIGAGMKIPTTGAIIVTVADKDKAEAV 960 KLR V+ TLGPEMKSTGEVMG+D KALYKGL+ +G+ IPT G++I+TVADKDK EA+ Sbjct: 892 KLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAM 951 Query: 961 ELMKGFHAMGYKIIATGGTALALEQAGLNVMNVNKLDEGEPTILDLIRSGQANFVFNTLT 1020 E+ K FH +GY ++AT GTA +L + + V VNK+D + +LD+IR G+A FV NTLT Sbjct: 952 EIAKRFHEIGYNLLATAGTAQSLTEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLT 1011 Query: 1021 KGKTPERDGFRIRREAVENGVVCMTSLDTVTALLRMLQTINFSSQSM 1067 KGK P RDGFRIRRE+VENGV C+TSLDT A+LR+L+++ FS+ SM Sbjct: 1012 KGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSM 1058 >sp|P46537|CARB_BACCL Carbamoyl-phosphate synthase, pyrimidine-specific, large chain (Carbamoyl-phosphate synthetase ammonia chain) pir||I40169 carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) - Bacillus caldolyticus emb|CAA51739.1| carbamoyl-phosphate synthase (glutamine-hydrolysing) [Bacillus caldolyticus] Length = 1065 Score = 1416 bits (3666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 698/1067 (65%), Positives = 840/1067 (78%), Gaps = 9/1067 (0%) Query: 1 MPKNEKLKKILVIGSGPIVIGQAAEFDYAGTQACQALKEEGVEVVLINSNPATIMTDTNM 60 MPK ++ ILVIGSGPIVIGQAAEFDYAGTQAC ALKEEG +V+L+NSNPATIMTDT + Sbjct: 1 MPKRRDIETILVIGSGPIVIGQAAEFDYAGTQACLALKEEGYKVILVNSNPATIMTDTEI 60 Query: 61 ADKVYIEPITLEFVTGIIRQERPDXXXXXXXXXXXXNMAVELARAGVLEQENVKLLGTQL 120 ADKVY+EP+TL+FV IIR+ERPD N+AVELA+AGVLE+ V++LGT+L Sbjct: 61 ADKVYMEPLTLDFVARIIRKERPDAILPTLGGQTGLNLAVELAKAGVLEECGVEILGTKL 120 Query: 121 GSIEKAEDRDLFRELMRELEQPVPESTIITSVEEAMGFAAGIGYPLIVRPAYTLGGTGGG 180 +IEKAEDR+ FR LM EL +PVPES II S+EEA F IGYP+IVRPA+TLGGTGGG Sbjct: 121 EAIEKAEDREQFRALMNELGEPVPESAIIHSLEEAYAFVEQIGYPVIVRPAFTLGGTGGG 180 Query: 181 ICDNEEELRETVKAGIRYSPIGQCLVEKSIAGMKEVEYEVMRDANDNCIVVCNMENFDPV 240 IC NEEEL E V G++ SP+ QCL+E+SIAG KE+EYEVMRDANDN IVVCNMEN DPV Sbjct: 181 ICTNEEELVEIVSTGLKLSPVHQCLLERSIAGYKEIEYEVMRDANDNAIVVCNMENIDPV 240 Query: 241 GVHTGDSIVVAPSQTLSDREYQMLRSASLKIIRALNIEGGCNVQFALDPQSYQYYVIEVN 300 G+HTGDSIVVAPSQTLSDREYQ+LR+ASLKIIRAL IEGGCNVQ ALDP S++YYVIEVN Sbjct: 241 GIHTGDSIVVAPSQTLSDREYQLLRNASLKIIRALGIEGGCNVQLALDPDSFRYYVIEVN 300 Query: 301 PRVSRSSALASKATGYPIAKMAAKIALGYTLDEIVNPVTGQTYACFEPTLDYIVSKIPRW 360 PRVSRSSALASKATGYPIAK+AAKIA+G TLDE++NPVTG+TYACFEP LDY+V+KIPR+ Sbjct: 301 PRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMINPVTGKTYACFEPALDYVVTKIPRF 360 Query: 361 PFDKFIYANRKLGTQMKATGEVMAIGRTFEESIHKAIRSLEIGIHRFKLPGAEQLEDSVL 420 PFDKF ANR+LGTQMKATGEVMAIGRTFEES+ KA+RSLEIG+H +L A+ D V+ Sbjct: 361 PFDKFESANRRLGTQMKATGEVMAIGRTFEESLLKAVRSLEIGVHHLELNEAKTAADDVM 420 Query: 421 RTRLAKADDERLFLIAEAFRRGYGLQEIQDITSVDWWFLSKIEGLVNFEEVIRSEATLSP 480 R+ KA DERLF IAEA RRG ++ + + + +D +FL KI+ ++ E V+++ Sbjct: 421 EKRIRKAGDERLFYIAEALRRGVTVETLHEWSQIDRFFLHKIQNIIEMETVLKNHPG-DL 479 Query: 481 ETLYQAKRKGFTDRAIAEIRAEGRPGLEQTKESEVRVLRLQQGLVPVFKMVDTCAAEFXX 540 + L +AK GF+D AIA L E ++ +R Q+G++PV+KMVDTCAAEF Sbjct: 480 DVLKKAKGLGFSDAAIA--------ALWNKTERDIYAVRRQRGIMPVYKMVDTCAAEFTS 531 Query: 541 XXXXXXXXXXXXXXVIHSDKQKVIVLGSGPIRIGQGIEFDYSTVHAVWAIQKAGYEAVII 600 I ++K VIVLGSGPIRIGQGIEFDY+TVH VWAI++AGYEA+II Sbjct: 532 ETPYYYSTYEEENESIVTEKPSVIVLGSGPIRIGQGIEFDYATVHCVWAIKQAGYEAIII 591 Query: 601 NNNPETVSTDFNTSDRLYFEPLFFEDVMNVIAQENPIGVIVQFGGQTXXXXXXXXXXXGV 660 NNNPETVSTDF+TSD+LYFEPL EDVM+VI E PIGVIVQFGGQT GV Sbjct: 592 NNNPETVSTDFSTSDKLYFEPLTAEDVMHVIDLEQPIGVIVQFGGQTAINLAAELEARGV 651 Query: 661 NILGTSLDSIDEAEDRKKFEALLARLDIAQPKGKTVINIDEAVETAQSLGYPVLVRPSYV 720 +LGT+L+ +D AEDR KFE L+ L I +P GKT ++++EAV A+ +GYPVLVRPSYV Sbjct: 652 RLLGTTLEDLDRAEDRDKFEQALSELGIPKPAGKTAVSVEEAVAIAEEIGYPVLVRPSYV 711 Query: 721 LGGRAMEIVYNDTELLSYMAEAVKVNPEHPVLIDRYMLGKEVEVDAICDGETVVIPGIME 780 LGGRAMEIVYN ELL YM AV+VNP+HPVL+DRY+ GKEVEVDAI DGETVVIPGIME Sbjct: 712 LGGRAMEIVYNRGELLHYMEHAVRVNPQHPVLVDRYITGKEVEVDAIADGETVVIPGIME 771 Query: 781 HVERAGVHSGDSIAVYPPQYLDEGLKQKIADITIKIAKELKTVGLVNIQFVIYQNEVYVI 840 H+ERAGVHSGDSIAVYPPQ L + KIAD TI++A+ L VGL+NIQFV+ ++VYV+ Sbjct: 772 HIERAGVHSGDSIAVYPPQTLSAEVIDKIADYTIRLARGLHIVGLLNIQFVVSGSDVYVL 831 Query: 841 EVNPRSSRTVPFLSKVTGIPMAHLATKTILGGKLKEEGYTEGLWPESDYVSVKVPVFSFA 900 EVNPRSSRTVPFLSK+TG+PMA+LATK ILG KL E GY G+ P V VKVPVFSFA Sbjct: 832 EVNPRSSRTVPFLSKITGVPMANLATKAILGTKLAEMGYETGVCPVRPGVYVKVPVFSFA 891 Query: 901 KLRRVEPTLGPEMKSTGEVMGRDKLYAKALYKGLIGAGMKIPTTGAIIVTVADKDKAEAV 960 KLR V+ +LGPEMKSTGEV+G+D + KALYKGL+ +G+ I GA+++TVADKDK EAV Sbjct: 892 KLRNVDISLGPEMKSTGEVIGKDVTFEKALYKGLVASGIHIQPHGAVLLTVADKDKEEAV 951 Query: 961 ELMKGFHAMGYKIIATGGTALALEQAGLNVMNVNKLDEGEPTILDLIRSGQANFVFNTLT 1020 EL + F +GY+++AT GTA L+ AG+ V VNK+ P ILD+IR G+A V NTLT Sbjct: 952 ELARRFADIGYQLLATNGTAETLKAAGIPVTVVNKIHSASPNILDVIRQGKAQVVINTLT 1011 Query: 1021 KGKTPERDGFRIRREAVENGVVCMTSLDTVTALLRMLQTINFSSQSM 1067 KGK PE DGFRIRREAVENG+ C+TSLDT A+L++L+++ FS+ +M Sbjct: 1012 KGKQPESDGFRIRREAVENGIPCLTSLDTARAMLQVLESMTFSTTAM 1058 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,466,071,772 Number of extensions: 60326259 Number of successful extensions: 172948 Number of sequences better than 1.0e-05: 2264 Number of HSP's gapped: 163374 Number of HSP's successfully gapped: 3806 Length of query: 1073 Length of database: 757,237,578 Length adjustment: 136 Effective length of query: 937 Effective length of database: 387,984,114 Effective search space: 363541114818 Effective search space used: 363541114818 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)