BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0263.0014.p
         (1337 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF 
           2,715,099 sequences; 757,237,578 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

pir||T44806 mycosubtilin synthetase chain mycA [imported] - Baci...   669   0.0  
ref|ZP_00160487.1| hypothetical protein Avar273201 [Anabaena var...   632   e-179
ref|ZP_00108797.1| COG3321: Polyketide synthase modules and rela...   442   e-122
ref|ZP_00107678.1| COG1020: Non-ribosomal peptide synthetase mod...   438   e-121
ref|NP_961164.1| hypothetical protein MAP2230c [Mycobacterium av...   432   e-119

>pir||T44806 mycosubtilin synthetase chain mycA [imported] - Bacillus subtilis
 gb|AAF08795.1| MycA [Bacillus subtilis]
          Length = 3971

 Score =  669 bits (1727), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 417/1253 (33%), Positives = 629/1253 (50%), Gaps = 93/1253 (7%)

Query: 26   TEMENLANVLVHVSANKDRGITFLQNDNSEFFLSYPALLEGATRRLGGLQEQGFTPGQYA 85
            ++ + L +V+ + S   DRGI F+++D  E F+SY  L + A   LG LQ  G  P Q  
Sbjct: 4    SQFQTLVDVIRNRSNISDRGIRFIESDKIETFVSYRQLFDEAQGFLGYLQHIGIQPKQEI 63

Query: 86   LILLEDSREFVLTFWACILGGIIPVPASYPASSKVINTSLSKLQAIWEVLERPLIISDHS 145
            +  +++++ FV+ FWAC+LGG+IPVP S        N    K+  IW +L  P +++  +
Sbjct: 64   VFQIQENKSFVVAFWACLLGGMIPVPVSIGED----NDHKLKVWRIWNILNNPFLLASET 119

Query: 146  LAEARDEMETTLGISGLRILEAAKLDTAGQTGTLMLAGAHTP-----AMIQFSSGSTSVP 200
            + +   +      +         K D          A  + P     A IQFSSGST  P
Sbjct: 120  VLDKMKKFAADHDLQDFHHQLIEKSDIIQDRIYDHPASQYEPEADELAFIQFSSGSTGDP 179

Query: 201  KGTILTHDNLLTNIESIITSSGMSEDDRSLGWMPYHHDMGLIGFHLSTLACGINQFNMTP 260
            KG +LTH NL+ N  +I  +  +   D  L WMP  HDMGLI  HL     GINQ  M  
Sbjct: 180  KGVMLTHHNLIHNTCAIRNALAIDLKDTLLSWMPLTHDMGLIACHLVPALAGINQNLMPT 239

Query: 261  MKFVKRPTLWLDMIDKHRITFTGCPNFGLRLVSSRVKEAQLKSWDLSSLRLLYNGAEPIS 320
              F++RP LW+    +H+ +    PNFG       +K+ +   WDLS +R++ NGAEPI 
Sbjct: 240  ELFIRRPILWMKKAHEHKASILSSPNFGYNYFLKFLKDNKSYDWDLSHIRVIANGAEPIL 299

Query: 321  VKTMREFMDKFEHSGLKRSAMYPVYGMAEACLAVSFPRPGEEPLVHSVNRERL-VGESRI 379
             +   EF+ +     +KRSA+  VYG+AEA +  +F   GE  +   ++R+ L +GE  +
Sbjct: 300  PELCDEFLTRCAAFNMKRSAILNVYGLAEASVGATFSNIGERFVPVYLHRDHLNLGERAV 359

Query: 380  EAIGENDRHASLIADEGYPVTGMEIRIVDDASGVVVPQGTVGEIQIRGRNVTSGYINNPE 439
            E   E+   AS + + G P+   +IRI ++A+  +   G +G IQI+G NVT GY NNPE
Sbjct: 360  EVSKEDQNCASFV-EVGKPIDYCQIRICNEANEGL-EDGFIGHIQIKGENVTQGYYNNPE 417

Query: 440  ATARSYQ-DGWLKTGDTGVVLDGRLSVIGRIKDIIFVNGQNFFAHDIEAVIEELDGVEPG 498
            +T R+   DGW+KTGD G +  G L V GR KDIIFVNG+N + HDIE V  EL+ ++ G
Sbjct: 418  STNRALTPDGWVKTGDLGFIRKGNLVVTGREKDIIFVNGKNVYPHDIERVAIELEDIDLG 477

Query: 499  KIAVCGWHDEQEGQERVGLFSTVRLQEQEVKPFYAKILRHVNEVIGIAVDYVSLIRSIPK 558
            ++A CG +D++     + LF+  +       P    I +H+ +  G ++  +  IR +PK
Sbjct: 478  RVAACGVYDQETRSREIVLFAVYKKSADRFAPLVKDIKKHLYQRGGWSIKEILPIRKLPK 537

Query: 559  TTSGKVQRFVLVEAFRKGEFQDKSYSAAFFAEETKGDYXXXXXXXXXXXXXXLEAPSLEA 618
            TTSGKV+R+ L E +  G+F  +S     F                           LE 
Sbjct: 538  TTSGKVKRYELAEQYESGKFALESTKIKEF---------------------------LEG 570

Query: 619  PSLEEPFPVAAPGAFLEK-IRGVWAEVLGRPPAAIPYNQSFMSMGGTSLKAIQILGALED 677
             S E   PV  P   +E  +  +++EV+      I  N  +  MG TSL+  QI   +E 
Sbjct: 571  HSTE---PVQTPIHEIETALLSIFSEVMD--GKKIHLNDHYFDMGATSLQLSQIAERIEQ 625

Query: 678  ELHIELTHDLLIQCRTIEEMDSYLARKVNMGGNPPSAGERQSAAVQGSGCGDAAIAVIAM 737
            +   ELT   L    +I ++ ++L            +  +Q+   + S      IA+I M
Sbjct: 626  KFGCELTVADLFTYPSIADLAAFLVEN--------HSEIKQTDTAKPSRSSSKDIAIIGM 677

Query: 738  ACRFPGASSPEEFWHNLLQGKDSIGEVPQDRWN--IDDYYSPTPEFGKIYCRNGGFLDNP 795
            +   PGAS+  +FWH L  G+  I E P  R    ID   S   E  +     GG+LD  
Sbjct: 678  SLNVPGASNKSDFWHLLENGEHGIREYPAPRVKDAIDYLRSIKSERNEKQFVRGGYLDEI 737

Query: 796  YGFDAALFGISGDEAAVMDPQQRIVMELVYELIERAGYSRQQMNGRDVGLFVGAGGNSYF 855
              FD + FG++   A  MDP QR+ ++  +  IE AGY+   ++G  +G++VG     Y 
Sbjct: 738  DRFDYSFFGLAPKTAKFMDPNQRLFLQSAWHAIEDAGYAGDTISGSQLGVYVGYSKVGY- 796

Query: 856  EYHLNTLNRMNLQSFDSFSTLTSVQQERIMEEWKRKLGVTGTHPNLLVDNIINMIPARTS 915
                             +  L S      +  +             +V N+ +++ +R +
Sbjct: 797  ----------------DYERLLSANYPEELHHY-------------IVGNLPSVLASRIA 827

Query: 916  QEFNFKGPSMAVDTACSSSLVTLHLAADSIRRGECESAIAGGIHLMLTPTSYQYFSSAEA 975
               N KGP++ VDTACSSSLV +H+A  ++  G+CE A+AGGI   L P         + 
Sbjct: 828  YFLNLKGPAVTVDTACSSSLVAVHMACKALLTGDCEMALAGGIRTSLLPMRI----GLDM 883

Query: 976  LSPTGRSSVFAADADGFVPGEGAGLVMLKPLEQALRDGDPVLAVLKASGINNDGHSIGVM 1035
             S  G +  F+ D+DG   GEG   V+LKPL+ A+RDGD +  V+K S IN DG ++G+ 
Sbjct: 884  ESSDGLTKTFSKDSDGTGSGEGVAAVLLKPLQAAIRDGDHIYGVIKGSAINQDGTTVGIT 943

Query: 1036 APNPDGQRELIESLYIRHNLSPADVQYVEAHGTGTKIGDPSEVRALDSAFKRWGLLRQSV 1095
            AP+P  Q E+IE  +    ++P  + ++EAHGTGTK+GDP E   L  AF++    +Q  
Sbjct: 944  APSPAAQTEVIEMAWKDAGIAPETLSFIEAHGTGTKLGDPVEFNGLCKAFEKVTEKKQFC 1003

Query: 1096 AIGSVKXXXXXXXXXXXXXXFIKVVMALQHKIMPPQINVSAPNPMLKFEKTPFYLLAAAQ 1155
            AIGSVK               IK  + L HK +PP  + + PNP++ F  +PFY+     
Sbjct: 1004 AIGSVKANIGHLFEAAGIVGLIKSALMLNHKKIPPLAHFNKPNPLIPFHSSPFYVNQEVM 1063

Query: 1156 EWPVAEGKARRAAINSFGFGGTNSHMVVEEAPARASAGEAEQPVRAKHVIGLSAQTEHAL 1215
            ++   E +  R  I+SFGF GTN+H+V+EE    +    A +     H+  LSA TE +L
Sbjct: 1064 DF-TPEDRPLRGGISSFGFSGTNAHVVLEEYTPESEY--APEDGNDPHLFVLSAHTEASL 1120

Query: 1216 QQKMLELAAFLEQHGDYPLADVCYTENAARTALPHRFHAVTDSVQDLIGKLQT 1268
             +   +   ++       L  +CYT +  R  L +    +  S Q+LI KL +
Sbjct: 1121 YELTHQYRQYISDDSQSSLRSICYTASTGRAHLDYCLAMIVSSNQELIDKLTS 1173



 Score = 69.3 bits (168), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 140/670 (20%), Positives = 251/670 (37%), Gaps = 158/670 (23%)

Query: 59   SYPALLEGATRRLGGLQEQGFTPGQYALILLEDSREFVLTFWACILGG--IIPVPASYP- 115
            +Y  L E   +    L+ +G    Q+  I+     E ++   A +  G   +P+   YP 
Sbjct: 2967 TYGQLNERVNQLARTLRTKGVQADQFVAIICPHRIELIVGILAVLKAGGAYVPIDPEYPE 3026

Query: 116  ---------ASSKVINTSLSKLQAIWEVLERPLIISDHSLAEARDEMETTLGISGLRILE 166
                     + +K++   L   + +    +  L+  + S  E R  +E T G + L    
Sbjct: 3027 DRIQYMLKDSEAKIVLAQLDLHKHLTFDADVVLLDEESSYHEDRSNLEPTCGANDL---- 3082

Query: 167  AAKLDTAGQTGTLMLAGAHTPAMIQFSSGSTSVPKGTILTHDNLLTNIESIITSSGMSED 226
                                 A + ++SGST  PKG ++ H  L   IE    +  +  +
Sbjct: 3083 ---------------------AYMIYTSGSTGNPKGVLIEHRGLANYIE---WAKEVYVN 3118

Query: 227  DRSLGWMPYHHDMGLIGFHLSTLACGINQFNMTPMKFVKRPTLWLDMIDKHRI--TFTGC 284
            D    +  Y      I F L+  +        TP+       +  D  DK  +  T    
Sbjct: 3119 DEKTNFPLY----SSISFDLTVTSI------FTPL-VTGNTIIVFDGEDKSAVLSTIMQD 3167

Query: 285  PNFGL-RLVSSRVKE-AQLKSWDLSSLRLLYNGAEPISVKTMREFMDKFEHSGLKRSAMY 342
            P   + +L  + +    ++K  D +++R +  G E +S +  +   ++F+     +  ++
Sbjct: 3168 PRIDIIKLTPAHLHVLKEMKIADGTTIRKMIVGGENLSTRLAQSVSEQFK----GQLDIF 3223

Query: 343  PVYGMAEACLAVSFPRPGEEPLVHSVNRERLVGESRIEAIGENDRHASLIADEGYPVTGM 402
              YG  EA +     R       +   R+R              R    I   G P    
Sbjct: 3224 NEYGPTEAVVGCMIYR-------YDTKRDR--------------REFVPI---GSPAANT 3259

Query: 403  EIRIVDDASGVVVPQGTVGEIQIRGRNVTSGYINNPEATARSYQDG-------WLKTGDT 455
             I ++D AS  +VP G  GE+ I G  V  GY N P+ TA  +            KTGD 
Sbjct: 3260 SIYVLD-ASMNLVPVGVPGEMYIGGAGVARGYWNRPDLTAEKFVHNPFAPGTIMYKTGDL 3318

Query: 456  GVVL-DGRLSVIGRIKDIIFVNGQNFFAHDIEAVIEELDGVEPGKIAVCGWHDEQEGQER 514
               L DG L  +GRI + + + G      ++EA + +++ V+    AV    +E++G ++
Sbjct: 3319 AKRLRDGNLIYLGRIDEQVKIRGHRIELGEVEAAMHKVEAVQK---AVVLAREEEDGLQQ 3375

Query: 515  VGLFSTVRLQEQEVKPFYAKILRHVNEVIGIAV-DYVS-----LIRSIPKTTSGKVQRFV 568
            +  +          KP     +  + E + + + DY+       +  +P T++GK+ R  
Sbjct: 3376 LCAYYVSN------KPI---TIAEIREQLSLELPDYMVPSHYIQLEQLPLTSNGKINR-- 3424

Query: 569  LVEAFRKGEFQDKSYSAAFFAEETKGDYXXXXXXXXXXXXXXLEAPSLEAPSLEEPFPVA 628
                                                      L AP +   SLE+     
Sbjct: 3425 ----------------------------------------KALPAPEV---SLEQIAEYV 3441

Query: 629  APGAFLE-KIRGVWAEVLGRPPAAIPYNQSFMSMGGTSLKAIQILGALEDELHIELTHDL 687
             PG  +E K+  +W E+LG     I +N  F  +GG S++A  +   +  EL + L+   
Sbjct: 3442 PPGNEVESKLAVLWQEMLGIHRVGIKHN--FFDLGGNSIRATALAARIHKELDVNLSVKD 3499

Query: 688  LIQCRTIEEM 697
            + +  TIE++
Sbjct: 3500 IFKFPTIEQL 3509


>ref|ZP_00160487.1| hypothetical protein Avar273201 [Anabaena variabilis ATCC 29413]
          Length = 1656

 Score =  632 bits (1629), Expect = e-179,   Method: Compositional matrix adjust.
 Identities = 453/1370 (33%), Positives = 656/1370 (47%), Gaps = 147/1370 (10%)

Query: 21   ITGRFTEMENLANVLVHVSANK--DRGITFLQNDNSEFF-LSYPALLEGATRRLGGLQEQ 77
            IT    E   L ++L + + N+      TFL +  +E   L+Y  L + A      L ++
Sbjct: 2    ITNDNVEFSTLVDLLRYRAQNQPTQTAYTFLVDGETESISLTYQELDQKARAIATQLLQR 61

Query: 78   GFTPGQYALILLEDSREFVLTFWACILGGIIPVPASYPASSKVINTSLSKLQAIWEVLER 137
            G  PG  AL+L     EF+  F+ C+  G I VPA YP      N  +S+LQAI      
Sbjct: 62   G-VPGSRALLLYPPGMEFIPAFFGCLYAGFIAVPA-YPPRR---NQKMSRLQAI------ 110

Query: 138  PLIISDHSLAEARDEMETTLGIS--GLRILEAAKLDTAGQTGTLMLAG------------ 183
               +SD   AEA   + T+  ++   L++ E   L       T  L              
Sbjct: 111  ---VSD---AEAVVALTTSTELTSMALQLAENPTLTAIPWITTDNLNANIAEDWQQPNIN 164

Query: 184  AHTPAMIQFSSGSTSVPKGTILTHDNLLTNIESIITSSGMSEDDRSLGWMPYHHDMGLIG 243
            + T A +Q++SGST  PKG ++TH NLL N + I      + + + + W+P +HDMGLIG
Sbjct: 165  SDTLAFLQYTSGSTGTPKGVMITHGNLLHNSQLIYNFYQHTPNSQGVIWLPPYHDMGLIG 224

Query: 244  FHLSTLACGINQFNMTPMKFVKRPTLWLDMIDKHRITFTGCPNFGLRLVSSRVKEAQLKS 303
              L  L  G     M P+ F+++P  WL  I  ++ T +G P+F   LV  ++   QL S
Sbjct: 225  GVLQPLYGGFPVTLMAPVAFLQKPFRWLQAISHYKATTSGGPDFAYDLVCRQITPEQLAS 284

Query: 304  WDLSSLRLLYNGAEPISVKTMREFMDKFEHSGLKRSAMYPVYGMAEACLAVSFPRPGEEP 363
             DLSS  + + GAEPI  +T+  F + F   G +R A YP YGMAE  L VS     E P
Sbjct: 285  LDLSSWEVAFTGAEPIRAQTLDRFAETFAPCGFRREAFYPCYGMAETTLIVSGGWKSEAP 344

Query: 364  LVHSVNRERLVGESRIEAIGENDRHASLIADEGYPVTGMEIRIVDDASGVVVPQGTVGEI 423
            +V  ++   L+    I+        A +   +  P     + IV+  S      G VGEI
Sbjct: 345  IVRHIDTTALLQNQVIDTTTAAGGKAIVGCGKSSP--DQTVLIVNPESLTSCADGQVGEI 402

Query: 424  QIRGRNVTSGYINNPEATARSYQ--------DGWLKTGDTGVVLDGRLSVIGRIKDIIFV 475
             + G +V  GY N PE T  ++           +L+TGD G + DG L + GR+KD+I +
Sbjct: 403  WVSGSSVAQGYWNRPEQTQHTFHAYLADNTTGPFLRTGDLGFLQDGELFITGRLKDLIII 462

Query: 476  NGQNFFAHDIEAVIEELD-GVEPGKIAVCGWHDEQEGQERVGLFSTVRLQEQEVKPFYAK 534
             G+N +  DIE  +E     + P   A   +  E    E++ +        QEV+  Y +
Sbjct: 463  MGRNHYPQDIEFTVESCHPALRPAGGA--AFAVEVNNVEKLVIV-------QEVERSYLR 513

Query: 535  ILRHVNEVIG-----------IAVDYVSLIR--SIPKTTSGKVQRFVLVEAFRKGEFQDK 581
             L + +EVIG           +    ++LI+  S+PKT+SGKV+R         G     
Sbjct: 514  KL-NADEVIGAIRKAVAEHHDLQTHTIALIKTNSLPKTSSGKVRRSNCKAELEAGSLDII 572

Query: 582  SYSAAFFAEETKGDYXXXXXXXXXXXXXXLEAPSLEAPSLEEPFPVAAPGAFL-EKIRGV 640
            +  +A     +  +                    L AP +E+     A   +L  K+   
Sbjct: 573  AQWSADAQNHSPSE-------------------KLIAPQVEKTVNTEAVATWLLTKV--- 610

Query: 641  WAEVLGRPPAAIPYNQSFMSMGGTSLKAIQILGALEDELHIELTHDLLIQCRTIEEMDSY 700
             +E L  P   I  N+     G  SL A++I G L++ L  EL   LL    +I  +  Y
Sbjct: 611  -SEQLQVPAQTINVNEPLAQYGLGSLAAVRISGELQEWLGRELPTTLLYDYPSIAALAQY 669

Query: 701  LARKVNMGGNPPSAGERQSAAVQGSGCGDAA-IAVIAMACRFPGASSPEEFWHNLLQGKD 759
            L   V      P    +Q         G AA IA++ + CR+PGA++PE FW  L  G D
Sbjct: 670  LGDGVPQ----PKVVSQQPTDNHAIASGGAAPIAIVGIGCRYPGANNPEAFWQLLRNGVD 725

Query: 760  SIGEVPQDRWNIDDYYSP---TPEFGKIYCRNGGFLDNPYGFDAALFGISGDEAAVMDPQ 816
            +I EVPQ RW+++ +Y P   TP  GK+  R GGF+     FDA  FGIS  EA  +DPQ
Sbjct: 726  AISEVPQQRWDVNSFYDPNRATP--GKMNTRWGGFISEVDQFDAPFFGISPREAESLDPQ 783

Query: 817  QRIVMELVYELIERAGYSRQQMNGRDVGLFVGAGGNSYFEYHLNTLNRMNLQSFDSFSTL 876
            QR+++E+ +E +E AG +  ++ G + G+FVG    S F+Y  + L    +   D++S  
Sbjct: 784  QRLLLEVCWEALENAGKAPSKLAGSNTGVFVGI---SNFDY--SQLLAKQVSGLDAYS-- 836

Query: 877  TSVQQERIMEEWKRKLGVTGTHPNLLVDNIINMIPARTSQEFNFKGPSMAVDTACSSSLV 936
                               GT       N  ++   R S   +  GPS AVDTACSSSLV
Sbjct: 837  -------------------GT------GNAFSIAANRISYLLDVHGPSWAVDTACSSSLV 871

Query: 937  TLHLAADSIRRGECESAIAGGIHLMLTPTSYQYFSSAEALSPTGRSSVFAADADGFVPGE 996
             +H A  S+R+GECE A+A G++L+LTP     FS A  ++  GR   F ADADG+V GE
Sbjct: 872  AVHQACQSLRQGECEMALAAGVNLILTPQLTVTFSQAGMMAGDGRCKTFDADADGYVRGE 931

Query: 997  GAGLVMLKPLEQALRDGDPVLAVLKASGINNDGHSIGVMAPNPDGQRELIESLYIRHNLS 1056
            G G+V+LK L  A RDGD +LAV+K S +N DG S G+ APN   Q+ +I        ++
Sbjct: 932  GCGVVVLKRLSDAYRDGDRILAVIKGSAVNQDGRSNGLTAPNGLAQQAVIRQAMQNAGVA 991

Query: 1057 PADVQYVEAHGTGTKIGDPSEVRALDSAFKRWGLLRQSVAIGSVKXXXXXXXXXXXXXXF 1116
            P ++ YVEAHGTGT +GDP EV +L +          +  IGSVK               
Sbjct: 992  PHEIGYVEAHGTGTFLGDPIEVNSLKTVLAPGRAPGDTCVIGSVKTNIGHLEAAAGIAGL 1051

Query: 1117 IKVVMALQHKIMPPQINVSAPNPMLKFEKTPFYLLAAAQEWPVAEGKARR-AAINSFGFG 1175
            IK V++L H+ +PP +++   NP +    T   +      W    G  RR A ++SFGFG
Sbjct: 1052 IKTVLSLHHEEIPPHLHLKQVNPHISLADTNLSIATTLLPW--NRGNKRRLAGVSSFGFG 1109

Query: 1176 GTNSHMVVEEAPARASAGEAEQPVRAKHVIGLSAQTEHALQQKMLELAAFLEQHGDYPLA 1235
            GTN+H+++EEAP   S  +     R  H+  LSA++E+AL+    +   +L  H D  L 
Sbjct: 1110 GTNAHIILEEAPL-VSPKDTVSDERPLHLFTLSAKSENALRDLAKDYENYLGNHPDASLT 1168

Query: 1236 DVCYTENAARTALPHRFHAVTDS---VQDLIGKLQTGXXXXXXXX------XXXXXXLMF 1286
            D+C+T N  R+   HR  A+  S   +Q ++G   TG                     +F
Sbjct: 1169 DICFTANTGRSHFDHRLVAIAQSNIQLQTVLGAYATGKKTSQLVSGKIENKQQPKIAFLF 1228

Query: 1287 TGQGSQYAGMGRALYDGLPAFRKNVDACSAAFEPYLDLKLTDLIXXXXKS 1336
            TGQGSQY  MGR LY   P FR  +D C      YLD  L  ++    +S
Sbjct: 1229 TGQGSQYINMGRQLYATQPTFRAAIDQCEQVLRSYLDQPLLSVLYPDTES 1278


>ref|ZP_00108797.1| COG3321: Polyketide synthase modules and related proteins [Nostoc
            punctiforme]
          Length = 2850

 Score =  442 bits (1137), Expect = e-122,   Method: Compositional matrix adjust.
 Identities = 259/703 (36%), Positives = 378/703 (53%), Gaps = 46/703 (6%)

Query: 642  AEVLG-RPPAAIPYNQSFMSMGGTSLKAIQILGALEDEL--HIELTHDLLIQCRTIEEMD 698
            A VLG  P   +  N+ F ++G  SL AI++   ++ +L     L   L     TI  + 
Sbjct: 941  ATVLGLEPTEKLDPNEGFATLGMKSLMAIELKNHIQTQLGHSYSLAATLAFDYPTITTLT 1000

Query: 699  SYLARKVNMGGNPPSAGER--QSAAVQGSGCGDAAIAVIAMACRFPG-ASSPEEFWHNLL 755
             YL R+V    +P +  E   QS     +      IA+IAM CRFPG A++PE+FW  L 
Sbjct: 1001 EYLGREVLNLDSPSTNHENLPQSCKDAINRISTEDIAIIAMGCRFPGGANNPEQFWQILQ 1060

Query: 756  QGKDSIGEVPQDRWNIDDYYSPTPEF-GKIYCRNGGFLDNPYGFDAALFGISGDEAAVMD 814
            +G D+I E+P  RWN+D+Y+   PE  GK+Y R+GGF+ +   FDA  FGIS  EA  +D
Sbjct: 1061 KGIDAITEIPSQRWNLDNYFDSEPETPGKMYTRHGGFIADIDQFDAQFFGISPREAISLD 1120

Query: 815  PQQRIVMELVYELIERAGYSRQQMNGRDVGLFVGAGGNSYFEYHLNTLNRMNLQSFDSFS 874
            PQQRI++E+ +E +E A  + Q + G   G+F+G   N Y +  +               
Sbjct: 1121 PQQRILLEVSWEALENAAIAPQNLVGSQTGVFIGLISNEYMQLQI--------------- 1165

Query: 875  TLTSVQQERIMEEWKRKLGVTGTHPNLLVDNIINMIPARTSQEFNFKGPSMAVDTACSSS 934
                  Q +  E+     G  G         I +    R S     +GPS+ VDTACSSS
Sbjct: 1166 ------QHKDPEKIDAYYGTGG---------IGSAAAGRISHSLGLRGPSLVVDTACSSS 1210

Query: 935  LVTLHLAADSIRRGECESAIAGGIHLMLTPTSYQYFSSAEALSPTGRSSVFAADADGFVP 994
            LV++HLA  S+RRGEC  A+AGG++L+L P +  + S ++A++  GR   F A A+GFV 
Sbjct: 1211 LVSIHLAVQSLRRGECNLALAGGVNLILLPETNIFLSKSKAVAADGRCKTFDASANGFVR 1270

Query: 995  GEGAGLVMLKPLEQALRDGDPVLAVLKASGINNDGHSIGVMAPNPDGQRELIESLYIRHN 1054
            GEG G+V+LK L +AL D DP+LAV++ S +N+DG S G   P+   Q+EL+       N
Sbjct: 1271 GEGCGVVVLKRLSEALADNDPILAVIRGSAVNHDGRSSGFTVPSTTAQQELLHQALANAN 1330

Query: 1055 LSPADVQYVEAHGTGTKIGDPSEVRALDSAFKRWGLLRQSVAIGSVKXXXXXXXXXXXXX 1114
            +    V Y+EAHGTGT +GDP EV AL S         Q + I SVK             
Sbjct: 1331 VEAQQVSYIEAHGTGTSLGDPIEVGALASVLCAGRSFEQPLVISSVKTNIGHLEAAAGVA 1390

Query: 1115 XFIKVVMALQHKIMPPQINVSAPNPMLKFEKTPFYLLAAAQEWPVAEGKARRAAINSFGF 1174
              +KVV+ALQH+ +PP +++  PNPM+ +E+ P  +  + Q W V +  AR   ++SFG 
Sbjct: 1391 GLMKVVLALQHQEIPPHLHLQQPNPMIAWEQLPLSVPTSGQSW-VVKDSARIGGVSSFGM 1449

Query: 1175 GGTNSHMVVEEAPARASAGE-----AEQPV-RAKHVIGLSAQTEHALQQKMLELAAFLEQ 1228
             GTN+H++V+EAP    AGE     AE  + R  H++ LSA+  ++L+Q   +   +L +
Sbjct: 1450 SGTNAHVIVQEAPL-GGAGEQGNRGAEITIERPLHLLCLSAKHSNSLRQLAEQYIDYLGK 1508

Query: 1229 HGDYPLADVCYTENAARTALPHRFHAVTDSVQDLIGKLQTGXXXXXXXX-XXXXXXLMFT 1287
            HGD  LA++ YT    R+   HR   +  S  ++  KL+                  +FT
Sbjct: 1509 HGDISLANITYTAQVGRSHFSHRLAVIASSHAEMQAKLEEAEYDYQVDSGNFTRCAFLFT 1568

Query: 1288 GQGSQYAGMGRALYDGLPAFRKNVDACSAAFEPYLDLKLTDLI 1330
            GQGSQY GMGR LY+  P FR+ +D C    + +L+  +  +I
Sbjct: 1569 GQGSQYVGMGRQLYETQPGFRRILDECDRILQLFLNKSILSVI 1611



 Score =  362 bits (930), Expect = 3e-98,   Method: Compositional matrix adjust.
 Identities = 222/633 (35%), Positives = 315/633 (49%), Gaps = 67/633 (10%)

Query: 731  AIAVIAMACRFPGASSPEEFWHNLLQGKDSIGEVPQDRWNIDDYYSP---TPEFGKIYCR 787
            AIAVI M CRFPGA +P  FW  L  G ++I +VP +RW++DD Y P   TP  G +  R
Sbjct: 12   AIAVIGMGCRFPGAKNPAAFWQMLRDGMNAITQVPANRWSMDDLYDPDLATP--GTMNSR 69

Query: 788  NGGFLDNPYGFDAALFGISGDEAAVMDPQQRIVMELVYELIERAGYSRQQMNGRDVGLFV 847
             GGFL N   FDA  FGIS  EAA  DPQQR+++E+ +E +E AG + QQ++G   G+++
Sbjct: 70   WGGFLQNVDQFDAKFFGISPGEAASTDPQQRLLLEVAWETLENAGLNPQQVSGSQTGVYI 129

Query: 848  GAGGNSYFEYHLNTLNRMNLQSFDSFSTLTSVQQERIMEEWKRKLGVTGTHPNLLVDNII 907
            G G N Y       L ++N                           VTG        N +
Sbjct: 130  GIGSNDYANVCFEDLTQLN------------------------AYFVTG--------NAL 157

Query: 908  NMIPARTSQEFNFKGPSMAVDTACSSSLVTLHLAADSIRRGECESAIAGGIHLMLTPTSY 967
                 R S  F ++GPS+A+DT CSSSLV +HLA  S+R  E + A+ G ++L+L+P + 
Sbjct: 158  CTTVNRLSYFFGWQGPSLALDTGCSSSLVAIHLACQSLRTREIDQALVGAVNLILSPKAN 217

Query: 968  QYFSSAEALSPTGRSSVFAADADGFVPGEGAGLVMLKPLEQALRDGDPVLAVLKASGINN 1027
               S A  ++       F A ADG+V GEG GLV+LK LE A+RD D +L +++ S +N 
Sbjct: 218  IGLSQAWMMTSDNCCKSFDAAADGYVRGEGCGLVLLKRLEDAIRDKDRILGIIRGSAVNQ 277

Query: 1028 DGHSIGVMAPNPDGQRELIESLYIRHNLSPADVQYVEAHGTGTKIGDPSEVRALDSAFKR 1087
            +G    + APN   Q+ +I        + P  + Y+EAHG GT + D +E  AL +  + 
Sbjct: 278  NGFGKNLTAPNQLAQQSVISQALANAGVEPQQISYIEAHGVGTPLADVTEASALKAVLRP 337

Query: 1088 WGLLRQSVAIGSVKXXXXXXXXXXXXXXFIKVVMALQHKIMPPQINVSAPNPMLKFEKTP 1147
             G       + SVK               IKV++  QH+ +PP ++    NP +  +  P
Sbjct: 338  EGDTLPCF-LSSVKTNIGHLEPAAGIAALIKVLLCFQHQEIPPHLHFQTLNPDIG-DDFP 395

Query: 1148 FYLLAAAQEWPVAEGKARRAAINSFGFGGTNSHMVVEEAP-----ARASAGEAEQPVRAK 1202
            F +   A  W +     R A INSFG GGTN+H+V+EE P      + S G  EQ  R  
Sbjct: 396  FIIPTTASPWEL-NNTPRLAGINSFGLGGTNAHLVLEEPPLERAEEQGSRGTEEQRSRGG 454

Query: 1203 --------HVIGLSAQTEHALQQKMLELAAFLEQH----GDYPLADVCYTENAARTALPH 1250
                    H++ LSA +E AL+    ELA     H     +  L D+CY+ N  R AL H
Sbjct: 455  ENTIERPLHLLTLSANSEKALR----ELANLYNTHIAKSVNIYLPDICYSANIGRAALKH 510

Query: 1251 RFHAVTDSVQDLIGKL------QTGXXXXXXXXXXXXXXLMFTGQGSQYAGMGRALYDGL 1304
            R   + D+ + L  +L      Q                 +FTGQG+QY  MGR LYD  
Sbjct: 511  RLAILVDTFESLQQELSAFASEQEAGEWFYGQQNSIKVGFLFTGQGTQYIDMGRELYDTQ 570

Query: 1305 PAFRKNVDACSAAFEPYLDLKLTDLIXXXXKSR 1337
            P FR+ ++ C     P+L+  L  ++     S+
Sbjct: 571  PVFREVLERCDRLLTPHLNKSLLSILYPESGSK 603


>ref|ZP_00107678.1| COG1020: Non-ribosomal peptide synthetase modules and related
            proteins [Nostoc punctiforme]
          Length = 4682

 Score =  438 bits (1126), Expect = e-121,   Method: Compositional matrix adjust.
 Identities = 271/759 (35%), Positives = 387/759 (50%), Gaps = 80/759 (10%)

Query: 615  SLEAPSLEEPFPVAAPGAFLEKIRGVW----AEVLGRPPAAIPYNQSFMSMGGTSLKAIQ 670
            SL+ PS +        G+ L+ I  V     A  LG+  + I  ++SF S G  SLKA++
Sbjct: 972  SLKIPSRQNEEVQVPQGSLLQWIGEVIVQQIANSLGKKSSQISLDKSFYSFGIDSLKAVE 1031

Query: 671  ILGALEDELHIELTHDLLIQCRT--------IEEMDSYLARKVNMGGNPPSAG----ERQ 718
            I+  L ++    ++  LL +  T        I+E  + L + + +   P        ERQ
Sbjct: 1032 IMETLGEKFGFSISPTLLFEYPTPTEFALYLIQEQKTQLQKYLLVNWEPAKLWAVNLERQ 1091

Query: 719  SAAVQGSGCGDAA----------------IAVIAMACRFPGASSPEEFWHNLLQGKDSIG 762
             A V  +   + A                IAVI M+ RFP +   + FW  L QGK++I 
Sbjct: 1092 KAVVLSNKLFNPASTKVVEPINDRIRAEDIAVIGMSGRFPQSPDLQSFWELLSQGKNAIA 1151

Query: 763  EVPQDRWNIDDYYSPTP-EFGKIYCRNGGFLDNPYGFDAALFGISGDEAAVMDPQQRIVM 821
            +VP  RWN+ D+Y   P    K Y   GGF+D+   FD   F IS  EA +MDPQQR+ +
Sbjct: 1152 QVPSLRWNLSDWYDKNPGAANKTYSCWGGFIDHIDQFDPLFFQISPREAELMDPQQRLFL 1211

Query: 822  ELVYELIERAGYSRQQMNGRDVGLFVGAGGNSYFEYHLNTLNRMNLQSFDSFSTLTSVQQ 881
            E+ +E +E AGYS +      VG+FVG   N Y++     LN                  
Sbjct: 1212 EVAWEALENAGYSPESFAQSQVGVFVGCSNNGYYQRIAPALN------------------ 1253

Query: 882  ERIMEEWKRKLGVTGTHPNLLVDNIINMIPARTSQEFNFKGPSMAVDTACSSSLVTLHLA 941
                 ++   +G    + N ++ N       R S   N +GPS+ +DT CSSSLV LH+A
Sbjct: 1254 ---TSDYSAGIG----NQNAIIAN-------RVSFLLNLRGPSVLIDTMCSSSLVALHMA 1299

Query: 942  ADSIRRGECESAIAGGIHLMLTPTSYQYFSSAEALSPTGRSSVFAADADGFVPGEGAGLV 1001
              S+++GEC +A+AGG++L+L+P  Y   S  +  SP GR + F + ADG V GEGAG +
Sbjct: 1300 CRSLQQGECTTALAGGVNLLLSPEYYVGMSRMKMHSPNGRCATFDSQADGIVLGEGAGAL 1359

Query: 1002 MLKPLEQALRDGDPVLAVLKASGINNDGHSIGVMAPNPDGQRELIESLYIRHNLSPADVQ 1061
            +LKPL QAL+DGD + AV+K S +N+DG + G+ APN     E+I        +S   + 
Sbjct: 1360 LLKPLSQALKDGDRIYAVIKGSAVNHDGRTNGITAPNSRSHAEVICQALDAAGISADTIS 1419

Query: 1062 YVEAHGTGTKIGDPSEVRALDSAFKRWGLLRQSVAIGSVKXXXXXXXXXXXXXXFIKVVM 1121
            YVEAHGTGT +GDP EV  L  AF+++   +Q   IGSVK               +KV++
Sbjct: 1420 YVEAHGTGTSLGDPIEVEGLTKAFRKYTERKQFCKIGSVKTNIGHLECAAGMAQLLKVIL 1479

Query: 1122 ALQHKIMPPQINVSAPNPMLKFEKTPFYLLAAAQEWPVAEGKARRAAINSFGFGGTNSHM 1181
            A+QH+ +P  ++   PNP++ F +TPF +      W       RRA I+SFG GGTN+H+
Sbjct: 1480 AIQHRQIPANLHFQQPNPLIPFAETPFQVNTKLCSW--ESSGLRRAGISSFGIGGTNAHI 1537

Query: 1182 VVEEAPA-RASAGEAEQPVRAKHVIGLSAQTEHALQQKMLELAAFLEQHGDYPLADVCYT 1240
            V+EEAP       E E+P   KH++  SA+TE+AL Q +     +L  + D PL D+C+T
Sbjct: 1538 VIEEAPPLEPVIPEIERP---KHLLTFSAKTENALVQLVSRYETYLAANLDLPLGDICFT 1594

Query: 1241 ENAARTALPHRFHAVTDSVQDLIGKLQ--------TGXXX-XXXXXXXXXXXLMFTGQGS 1291
             N  R+   HR  A+  S  DL  +L         TG                +FTGQ S
Sbjct: 1595 ANTGRSHFQHRLSAIATSTSDLHQRLLNFISQQEVTGIKIGRIHENTPPKIAFLFTGQCS 1654

Query: 1292 QYAGMGRALYDGLPAFRKNVDACSAAFEPYLDLKLTDLI 1330
            QY GMG  LY+  P FRK +D C+    PYL   L  +I
Sbjct: 1655 QYVGMGSQLYETQPTFRKILDYCNEILRPYLKEDLLKVI 1693



 Score =  245 bits (625), Expect = 7e-63,   Method: Compositional matrix adjust.
 Identities = 170/546 (31%), Positives = 270/546 (49%), Gaps = 23/546 (4%)

Query: 47  TFLQN-DNSEFFLSYPALLEGATRRLGGLQEQGFTPGQYALILLEDSREFVLTFWACILG 105
           TFL + D  E  L+Y  L + A      LQ     PG+ AL+L     EF++ F+ C+  
Sbjct: 27  TFLVDGDTEEVKLTYQELDQKARAIAVELQSLKAAPGERALLLYPSGLEFIVAFFGCLYA 86

Query: 106 GIIPVPASYPASSKVINTSLSKLQAIWEVLERPLIISDHS-LAEARDEMETTLGISGLRI 164
           G++ VP  YP      N  +++LQAI +  E    ++  S L   +        ++ L  
Sbjct: 87  GVLAVPV-YPPRR---NQRMTRLQAIVKDSEARFALTTASVLTNIQQGFAQEPELTALHC 142

Query: 165 LEAAKLDTAGQTGTLMLAGAHTPAMIQFSSGSTSVPKGTILTHDNLLTNIESIITSSGMS 224
           +   K+ +             T A +Q++SGST  PKG I+TH NLL N E I ++  ++
Sbjct: 143 IAIDKIVSDASNWQKPPLEKSTLAFLQYTSGSTGTPKGVIVTHGNLLQNSEYIKSAFELT 202

Query: 225 EDDRSLGWMPYHHDMGLIGFHLSTLACGINQFNMTPMKFVKRPTLWLDMIDKHRITFTGC 284
            +  S+ W+P  HDMGLI   L  L  G     M+P  FV++P  WL  I  ++ T  G 
Sbjct: 203 PNSVSVTWLPSFHDMGLIDGVLQPLYTGFPSVMMSPASFVQQPIRWLKAISDYKATHCGG 262

Query: 285 PNFGLRLVSSRVKEAQLKSWDLSSLRLLYNGAEPISVKTMREFMDKFEHSGLKRSAMYPV 344
           PNFG  L  S++   Q  + DLSS    Y+GAEP+  +T+ +F   F+ SG +    YP 
Sbjct: 263 PNFGYELCVSKITPEQRANLDLSSWCSAYSGAEPVRRETLEKFAATFKSSGFQAKFFYPC 322

Query: 345 YGMAEACLAVSFPRPGEEPLVHSVNRERLVGESRIEAIGENDRHASLIADEGYPVTGMEI 404
           YGMAEA L +S     +EP V+ V   + + +++I  + E+      +   GY     +I
Sbjct: 323 YGMAEATLMISGGGVADEP-VYCVVDPKALEKNQIIQVSEDTPKVKHLVGCGYAWLDTKI 381

Query: 405 RIVDDASGVVVPQGTVGEIQIRGRNVTSGYINNPEATARSY--------QDGWLKTGDTG 456
            I +  S  +     VGEI + G ++  GY N PE T  ++        +  +L+TGD G
Sbjct: 382 AIANPQSLTLCAPEQVGEIWVSGSSIAKGYWNRPEQTKETFHAYLADTAEGPFLRTGDLG 441

Query: 457 VVLDGRLSVIGRIKDIIFVNGQNFFAHDIEAVIEEL-DGVEPGKIAVCGWHDEQEGQERV 515
            + DG+L + GR+KD++ + G N +  DIE  +E+    ++ G  A   +  + +G+E++
Sbjct: 442 FLKDGQLFITGRLKDVVIIRGCNHYPQDIELTVEQSHQALKAGSGA--AFSVDIDGEEQL 499

Query: 516 GLFSTVR---LQEQEVKPFYAKILRHVNEVIGIAVDYVSLIR--SIPKTTSGKVQRFVLV 570
            +   V    L+   +      I   V+++  + V  V L++  SIPKT+SGK+QR    
Sbjct: 500 VIVQEVERTYLRHLNLDEVVEAIKTSVSQIHELQVYAVLLLKTGSIPKTSSGKIQRHACR 559

Query: 571 EAFRKG 576
             F  G
Sbjct: 560 AGFLAG 565


>ref|NP_961164.1| hypothetical protein MAP2230c [Mycobacterium avium subsp.
            paratuberculosis str. k10]
 gb|AAS04547.1| hypothetical protein MAP2230c [Mycobacterium avium subsp.
            paratuberculosis str. k10]
          Length = 3679

 Score =  432 bits (1110), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 260/714 (36%), Positives = 374/714 (52%), Gaps = 45/714 (6%)

Query: 635  EKIRGVWAEVLGRPPAAIPYNQSFMSMGGTSLKAIQILGALEDELHIELTHDLLIQCRTI 694
            E +R   AEV     A I  +  F  +G  SL AI++   +E  +  ++   L +    +
Sbjct: 1463 EFLRNAVAEVTRVDAAEIREDAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRL 1522

Query: 695  EEMDSYLARKV-NMGGNPPSAGERQSAAVQGSGCGDAAIAVIAMACRFPGASSPEEFWHN 753
             ++  YL   V ++ G P +     +     +G  D  IA+++MACRFPGA+ PE FW  
Sbjct: 1523 SDVAEYLLGDVLDLRGQPDAKPAPPAGTPAPAGRTDEPIAIVSMACRFPGAADPEAFWEL 1582

Query: 754  LLQGKDSIGEVPQDRWNIDDYYSPTPEF-GKIYCRNGGFLDNPYGFDAALFGISGDEAAV 812
            L  G D+I EVP+DR++ID++Y P PE  GK+Y R GG+LD    F+   FGIS  EA  
Sbjct: 1583 LSGGVDAIREVPEDRFDIDEFYDPDPETPGKMYSRFGGYLDQIDEFEPEFFGISPREAVW 1642

Query: 813  MDPQQRIVMELVYELIERAGYSRQQMNGRDVGLFVGAGGNSYFEYHLNTLNRMNLQSFDS 872
            +DPQQR+ +E V+E +ERAGYS   + G   G+FVG G N Y   HL     ++ +S D 
Sbjct: 1643 IDPQQRLALETVWEGLERAGYSPAALRGSRSGIFVGVGANEY--SHL-----LSAESVDK 1695

Query: 873  FSTLTSVQQERIMEEWKRKLGVTGTHPNLLVDNIINMIPARTSQEFNFKGPSMAVDTACS 932
                                      P+ +  N +N I  R +     +GP++AVDTACS
Sbjct: 1696 I------------------------EPHFITGNALNAISGRVAFALGLEGPAVAVDTACS 1731

Query: 933  SSLVTLHLAADSIRRGECESAIAGGIHLMLTPTSYQYFSSAEALSPTGRSSVFAADADGF 992
            SSLV +H A  ++  G+C+ A+AGG++++L+P S    S A  LSP GR   F A ADG+
Sbjct: 1732 SSLVAVHQACQALHSGDCDLALAGGVNVLLSPVSNIAASRARMLSPVGRCKTFDATADGY 1791

Query: 993  VPGEGAGLVMLKPLEQALRDGDPVLAVLKASGINNDGHSIGVMAPNPDGQRELIESLYIR 1052
            V  EG G+++LK +  A+RDGD V AV+ AS +N DG S G+  PN   Q+ LI +   R
Sbjct: 1792 VRSEGCGILVLKRMSDAVRDGDRVCAVIPASAVNQDGASSGLTVPNGGAQQRLIATALSR 1851

Query: 1053 HNLSPADVQYVEAHGTGTKIGDPSEVRALDSAFKRWGLLRQSVAIGSVKXXXXXXXXXXX 1112
              LS  DV Y+EAHGTGT +GDP EV+A  + +       + + IGSVK           
Sbjct: 1852 AGLSGDDVDYLEAHGTGTALGDPIEVQAAGAVYGATRDTDRPLLIGSVKTNIGHLEAASG 1911

Query: 1113 XXXFIKVVMALQHKIMPPQINVSAPNPMLKFEKTPFYLLAAAQEWPVAEGKARRAAINSF 1172
                IKVV++LQH+++P  ++   P+P + ++  P  ++  A  W    G+ RRA ++SF
Sbjct: 1912 VAGLIKVVLSLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQT-NGRPRRAGVSSF 1970

Query: 1173 GFGGTNSHMVVEEAP----ARASAGEAEQPVRAKHVIGLSAQTEHALQQKMLELAAFLEQ 1228
            GF GTN+H+++EEAP     + +   AE   R   V+ LSA++  AL         +L  
Sbjct: 1971 GFTGTNAHVLIEEAPQPVTTQHATPAAESDARPVDVLPLSARSPEALLALAQRYGEWLHA 2030

Query: 1229 HGDYPLADVCYTENAARTALPHRFHAVTDSVQ-------DLIGKLQTGXXXXXXXXXXXX 1281
            H D  + D+C+T  A R    HR   V DSV+       DL                   
Sbjct: 2031 HPDADIGDLCFTVGAGRAHFEHRAALVVDSVRSAREALADLADNRTRPGVARGECTDPPT 2090

Query: 1282 XXLMFTGQGSQYAGMGRALYDGLPAFRKNVDACSAAFEPYLDLKLTDLIXXXXK 1335
               +FTGQGSQY GM R L+D  P F + V  C+ A +  L   LT++I    K
Sbjct: 2091 TAWLFTGQGSQYPGMARELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDK 2144



 Score =  385 bits (989), Expect = e-105,   Method: Compositional matrix adjust.
 Identities = 217/617 (35%), Positives = 325/617 (52%), Gaps = 49/617 (7%)

Query: 730  AAIAVIAMACRFPGASSPEEFWHNLLQGKDSIGEVPQDRWNIDDYYSPTPEF-GKIYCRN 788
            ++ A++  A RFP A+  +EFW  L +G+D++ EVP+DRW+ D+++ P P+  GK+  R 
Sbjct: 12   SSFAIVGYAARFPDAADADEFWRVLAEGRDAVSEVPKDRWDADEFFDPDPDAPGKVVTRR 71

Query: 789  GGFLDNPYGFDAALFGISGDEAAVMDPQQRIVMELVYELIERAGYSRQQMNGRDVGLFVG 848
             GF+D+  GFDA  FG+S  EA ++DPQ R+++E  +  +E  G +   +   + G+F+G
Sbjct: 72   AGFVDDVTGFDAPFFGMSAREARLLDPQHRLLLETAWRAVEHCGTAPTDLANTNTGVFIG 131

Query: 849  AGGNSYFEYHLNTLNRMNLQSFDSFSTLTSVQQERIMEEWKRKLGVTGTHPNLLVDNIIN 908
               + Y     + L    ++++ +  T ++    RI                        
Sbjct: 132  ISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGRI------------------------ 167

Query: 909  MIPARTSQEFNFKGPSMAVDTACSSSLVTLHLAADSIRRGECESAIAGGIHLMLTPTSYQ 968
                  S     +GP++AVDTACSSSLV +H A  ++R GEC+ A+AGG +++LTP +  
Sbjct: 168  ------SYRLGLQGPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMI 221

Query: 969  YFSSAEALSPTGRSSVFAADADGFVPGEGAGLVMLKPLEQALRDGDPVLAVLKASGINND 1028
             FS A  L+P GR   F A ADG+V GEG G++++K LE A+RDGD + AV++ S IN D
Sbjct: 222  TFSQAHMLAPDGRCKTFDAAADGYVRGEGCGVLVVKRLEDAIRDGDRIRAVIRGSAINQD 281

Query: 1029 GHSIGVMAPNPDGQRELIESLYIRHNLSPADVQYVEAHGTGTKIGDPSEVRALDSAFKRW 1088
            G S G+  PN   Q+ +I     R  ++P DV Y+EAHGTGT +GDP EV+A  +     
Sbjct: 282  GASGGLTVPNGVAQQRVIAEALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAG 341

Query: 1089 GLLRQSVAIGSVKXXXXXXXXXXXXXXFIKVVMALQHKIMPPQINVSAPNPMLKFEKTPF 1148
                + + IGSVK               IKV++AL+H ++P  ++   P+P + +++   
Sbjct: 342  REASRPLLIGSVKTNIGHLEAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLAV 401

Query: 1149 YLLAAAQEWPVAEGKARRAAINSFGFGGTNSHMVVEEAPARASAGEAEQP--------VR 1200
             ++  A  W    G+ R A ++SFGF GTN+H+++EEAP     G A  P         R
Sbjct: 402  QVVKEATAWQ-RNGRPRVAGVSSFGFAGTNAHVILEEAP--DGTGRAAVPPAAVRPPGQR 458

Query: 1201 AKHVIGLSAQTEHALQQKMLELAAFLEQHGDYPLADVCYTENAARTALPHRFHAVTDSV- 1259
              HV+ LSA+T  AL Q   E   +L  H D  LAD+C T  A R    HR   V DS  
Sbjct: 459  RFHVLPLSARTPAALVQIAGEYRDWLSAHPDTALADLCLTAGAGRAHFEHRAALVVDSTG 518

Query: 1260 --QDLIGKLQTGXXX----XXXXXXXXXXXLMFTGQGSQYAGMGRALYDGLPAFRKNVDA 1313
               +L+  L                      +FTGQGSQYAGM R L+D  P F + +  
Sbjct: 519  SAGELLAALADDRPAPGLLRGVCEDAPKTAWLFTGQGSQYAGMARELFDTEPVFAETLTR 578

Query: 1314 CSAAFEPYLDLKLTDLI 1330
            C+      L+  L D+I
Sbjct: 579  CATVLADVLEKPLLDVI 595


  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF
    Posted date:  Mar 24, 2004  1:53 AM
  Number of letters in database: 757,237,578
  Number of sequences in database:  2,715,099
  
Lambda     K      H
   0.318    0.135    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 2715099
Number of Hits to DB: 1,922,785,582
Number of extensions: 81335520
Number of successful extensions: 210659
Number of sequences better than 1.0e-05: 4168
Number of HSP's gapped: 201644
Number of HSP's successfully gapped: 5172
Length of query: 1337
Length of database: 757,237,578
Length adjustment: 138
Effective length of query: 1199
Effective length of database: 382,553,916
Effective search space: 458682145284
Effective search space used: 458682145284
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 132 (55.5 bits)