BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0256.0033.p (368 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gb|EAI21259.1| unknown [environmental sequence] 277 3e-73 ref|NP_462389.1| dehydroquinate synthase [Salmonella typhimurium... 277 3e-73 ref|NP_458418.1| 3-dehydroquinate synthase [Salmonella enterica ... 277 3e-73 ref|NP_312258.1| 3-dehydroquinate synthase [Escherichia coli O15... 272 1e-71 ref|NP_289928.1| 3-dehydroquinate synthase [Escherichia coli O15... 271 1e-71 >gb|EAI21259.1| unknown [environmental sequence] Length = 359 Score = 277 bits (709), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 151/361 (41%), Positives = 210/361 (58%), Gaps = 6/361 (1%) Query: 1 MMRSITVELGERSYPIHIGSGLLRDIGQHCVKAGFPLRSPLLIVSDSEVAPRYLPVVEAA 60 M + I V+LGERSYPI+IG L+ D G+ + + L+ +LIV++ VAP YL ++ Sbjct: 1 MTKQIQVDLGERSYPIYIGQSLMSD-GETLSR--YLLKKRILIVTNETVAPLYLKQIQDT 57 Query: 61 LRGEGYAVVSHVIPAGEASKSLAVYEEVITTAIQAGLDRSSXXXXXXXXXXXXXXXXXXX 120 + G V S ++P GE K L + + T +Q R S Sbjct: 58 MASFG-EVTSVILPDGEQFKDLTHLDSIFTALLQRNYGRDSVLVALGGGVIGDMTGFAAA 116 Query: 121 TFMRGIGFIQIPTTILAH-DSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPPR 179 + RG+ FIQIPTT+L+ DSSVGGK AVNHPL KNMIGAFYQP +V+ D + L TLP R Sbjct: 117 CYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQIVIIDTECLQTLPAR 176 Query: 180 QISSGLAEVVKHGLILDRDFAYWCLEHASELLSLNTEALGYALERGCAIKAQVVSNDERE 239 + ++G+AEV+K+G++ D +F W + L SL+T+AL YA+ R C IKA VVS DE E Sbjct: 177 EFAAGMAEVIKYGIMWDAEFFQWLENNVQALKSLDTQALVYAISRCCEIKADVVSQDETE 236 Query: 240 HGQRAFLNLGHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLGR-ERAIYEDTIAM 298 G RA LNLGHT GHAIEA GYG +LHGEA+A G +A A +G + +I + + Sbjct: 237 QGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTVLAAQTAKSMGLIDESIVRRIVQL 296 Query: 299 LSALSLPVKLPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVREVL 358 A LPV P D ++ M DKK G++ ++P +IG + + V S + +V+ Sbjct: 297 FHAFDLPVTAPESMDFDSFIKHMRRDKKVLGGQIRLVLPTAIGRADVFSQVPESTLEQVI 356 Query: 359 A 359 Sbjct: 357 C 357 >ref|NP_462389.1| dehydroquinate synthase [Salmonella typhimurium LT2] sp|P77980|AROB_SALTY 3-dehydroquinate synthase emb|CAA69932.1| 3-dehydroquinate synthase [Salmonella typhimurium] gb|AAL22348.1| dehydroquinate synthase [Salmonella typhimurium LT2] Length = 362 Score = 277 bits (708), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 157/366 (42%), Positives = 214/366 (58%), Gaps = 9/366 (2%) Query: 2 MRSITVELGERSYPIHIGSGLLRDIGQHCVKAGFPLRS--PLLIVSDSEVAPRYLPVVEA 59 M ITV LGERSYPI I +GL + PL+S +++V++ +AP YL V Sbjct: 1 MERITVTLGERSYPITIAAGLFNEPASF-----LPLKSGDQVMLVTNETLAPLYLDKVRG 55 Query: 60 ALRGEGYAVVSHVIPAGEASKSLAVYEEVITTAIQAGLDRSSXXXXXXXXXXXXXXXXXX 119 L G V S ++P GE KSL V + V T ++ R + Sbjct: 56 VLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAA 115 Query: 120 XTFMRGIGFIQIPTTILAH-DSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPP 178 ++ RG+ FIQ+PTT+L+ DSSVGGK AVNHPL KNMIGAFYQP+ V+ DLD L TLP Sbjct: 116 ASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPA 175 Query: 179 RQISSGLAEVVKHGLILDRDFAYWCLEHASELLSLNTEALGYALERGCAIKAQVVSNDER 238 R+++SGLAEV+K+G+ILD DF W + LL L+ A+ Y + R C +KA+VV+ DER Sbjct: 176 RELTSGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADER 235 Query: 239 EHGQRAFLNLGHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLGR-ERAIYEDTIA 297 E G RA LNLGHT GHAIEA GYG +LHGEA+A G+ +A + +LG+ A + IA Sbjct: 236 EAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIA 295 Query: 298 MLSALSLPVKLPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVREV 357 +L LPV P E S + + M+ DKK G++ ++P +IG + V V Sbjct: 296 LLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSA 355 Query: 358 LAQLKK 363 +A ++ Sbjct: 356 IADCQQ 361 >ref|NP_458418.1| 3-dehydroquinate synthase [Salmonella enterica subsp. enterica serovar Typhi] ref|NP_807630.1| 3-dehydroquinate synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2] sp|Q8Z205|AROB_SALTI 3-dehydroquinate synthase pir||AD1000 3-dehydroquinate synthase (EC 4.2.3.4) [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) emb|CAD08128.1| 3-dehydroquinate synthase [Salmonella enterica subsp. enterica serovar Typhi] gb|AAO71490.1| 3-dehydroquinate synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2] Length = 362 Score = 277 bits (708), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 157/366 (42%), Positives = 214/366 (58%), Gaps = 9/366 (2%) Query: 2 MRSITVELGERSYPIHIGSGLLRDIGQHCVKAGFPLRS--PLLIVSDSEVAPRYLPVVEA 59 M ITV LGERSYPI I +GL + PL+S +++V++ +AP YL V Sbjct: 1 MERITVTLGERSYPITIAAGLFNEPASF-----LPLKSGDQVMLVTNETLAPLYLDKVRG 55 Query: 60 ALRGEGYAVVSHVIPAGEASKSLAVYEEVITTAIQAGLDRSSXXXXXXXXXXXXXXXXXX 119 L G V S ++P GE KSL V + V T ++ R + Sbjct: 56 VLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAA 115 Query: 120 XTFMRGIGFIQIPTTILAH-DSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPP 178 ++ RG+ FIQ+PTT+L+ DSSVGGK AVNHPL KNMIGAFYQP+ V+ DLD L TLP Sbjct: 116 ASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPA 175 Query: 179 RQISSGLAEVVKHGLILDRDFAYWCLEHASELLSLNTEALGYALERGCAIKAQVVSNDER 238 R+++SGLAEV+K+G+ILD DF W + LL L+ A+ Y + R C +KA+VV+ DER Sbjct: 176 RELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADER 235 Query: 239 EHGQRAFLNLGHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLGR-ERAIYEDTIA 297 E G RA LNLGHT GHAIEA GYG +LHGEA+A G+ +A + +LG+ A + IA Sbjct: 236 EAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIA 295 Query: 298 MLSALSLPVKLPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVREV 357 +L LPV P E S + + M+ DKK G++ ++P +IG + V V Sbjct: 296 LLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLTIGKSEVRGGVSHEVVLSA 355 Query: 358 LAQLKK 363 +A ++ Sbjct: 356 IADCQQ 361 >ref|NP_312258.1| 3-dehydroquinate synthase [Escherichia coli O157:H7] sp|Q8X824|AROB_ECO57 3-dehydroquinate synthase pir||G91157 3-dehydroquinate synthase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) dbj|BAB37654.1| 3-dehydroquinate synthase [Escherichia coli O157:H7] Length = 362 Score = 272 bits (695), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 162/365 (44%), Positives = 214/365 (58%), Gaps = 9/365 (2%) Query: 2 MRSITVELGERSYPIHIGSGLLRDIGQHCVKAGFPLRS--PLLIVSDSEVAPRYLPVVEA 59 M I V LGERSYPI I SGL + PL+S +++V++ +AP YL V Sbjct: 1 MERIVVTLGERSYPITIASGLFNEPASF-----LPLKSGEQVMLVTNETLAPLYLDKVRG 55 Query: 60 ALRGEGYAVVSHVIPAGEASKSLAVYEEVITTAIQAGLDRSSXXXXXXXXXXXXXXXXXX 119 L G V S ++P GE KSLAV + V T +Q R + Sbjct: 56 VLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAA 115 Query: 120 XTFMRGIGFIQIPTTILAH-DSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPP 178 ++ RG+ FIQ+PTT+L+ DSSVGGK AVNHPL KNMIGAFYQP+ V+ DLD L TLPP Sbjct: 116 ASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPP 175 Query: 179 RQISSGLAEVVKHGLILDRDFAYWCLEHASELLSLNTEALGYALERGCAIKAQVVSNDER 238 R+++SGLAEV+K+G+ILD F W E+ LL L+ A+ Y + R C +KA+VV+ DER Sbjct: 176 RELASGLAEVIKYGIILDGTFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADER 235 Query: 239 EHGQRAFLNLGHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLGR-ERAIYEDTIA 297 E G RA LNLGHT GHAIEA GYG +LHGEA+A GM +A + +LG+ A + I Sbjct: 236 ETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIIT 295 Query: 298 MLSALSLPVKLPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVREV 357 +L+ LPV P E S + M+ DKK G+M I+P +IG + + V V Sbjct: 296 LLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNA 355 Query: 358 LAQLK 362 +A + Sbjct: 356 IADCQ 360 >ref|NP_289928.1| 3-dehydroquinate synthase [Escherichia coli O157:H7 EDL933] pir||E86003 3-dehydroquinate synthase [imported] - Escherichia coli (strain O157:H7, substrain EDL933) gb|AAG58489.1| 3-dehydroquinate synthase [Escherichia coli O157:H7 EDL933] Length = 362 Score = 271 bits (694), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 163/365 (44%), Positives = 215/365 (58%), Gaps = 9/365 (2%) Query: 2 MRSITVELGERSYPIHIGSGLLRDIGQHCVKAGFPLRS--PLLIVSDSEVAPRYLPVVEA 59 M I V LGERSYPI I SGL + PL+S +++V++ +AP YL V Sbjct: 1 MERIVVTLGERSYPITIASGLFNEPASF-----LPLKSGEQVMLVTNETLAPLYLDKVRG 55 Query: 60 ALRGEGYAVVSHVIPAGEASKSLAVYEEVITTAIQAGLDRSSXXXXXXXXXXXXXXXXXX 119 L G V S ++P GE KSLAV + V T +Q R + Sbjct: 56 VLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAX 115 Query: 120 XTFMRGIGFIQIPTTILAH-DSSVGGKVAVNHPLAKNMIGAFYQPSLVLYDLDTLSTLPP 178 ++ RG+ FIQ+PTT+L+ DSSVGGK AVNHPL KNMIGAFYQP+ V+ DLD L TLPP Sbjct: 116 ASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPP 175 Query: 179 RQISSGLAEVVKHGLILDRDFAYWCLEHASELLSLNTEALGYALERGCAIKAQVVSNDER 238 R+++SGLAEV+K+G+ILD F W E+ LL L+ A+ Y + R C +KA+VV+ DER Sbjct: 176 RELASGLAEVIKYGIILDGTFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADER 235 Query: 239 EHGQRAFLNLGHTIGHAIEAVGGYGVFLHGEAIAIGMAGSALLAAKLGR-ERAIYEDTIA 297 E G RA LNLGHT GHAIEA GYG +LHGEA+A GM +A + +LG+ A + I Sbjct: 236 ETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIIT 295 Query: 298 MLSALSLPVKLPAEYSEDELMEAMMHDKKFKEGKMTFIVPDSIGAVSIVNDVQPSAVREV 357 +L+ LPV P E S + M+ DKK G+M I+P +IG + + V V Sbjct: 296 LLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNA 355 Query: 358 LAQLK 362 +A + Sbjct: 356 IADCQ 360 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 469,162,549 Number of extensions: 17800566 Number of successful extensions: 47166 Number of sequences better than 1.0e-05: 664 Number of HSP's gapped: 45647 Number of HSP's successfully gapped: 668 Length of query: 368 Length of database: 757,237,578 Length adjustment: 127 Effective length of query: 241 Effective length of database: 412,420,005 Effective search space: 99393221205 Effective search space used: 99393221205 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)