BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0256.0025.p (365 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242531.1| histidinol-phosphate aminotransferase; histidin... 360 3e-98 dbj|BAC11847.1| histidinol-phosphate aminotransferase [Bacillus ... 350 3e-95 ref|NP_390143.1| histidinol-phosphate aminotransferase; tyrosine... 350 4e-95 ref|NP_977966.1| histidinol-phosphate aminotransferase [Bacillus... 323 3e-87 ref|NP_655419.1| aminotran_1_2, Aminotransferase class I and II ... 321 2e-86 >ref|NP_242531.1| histidinol-phosphate aminotransferase; histidinol-phosphate aminotransferase/tyrosine and phenylalanine aminotransferase [Bacillus halodurans] sp|Q9KCA8|HIS8_BACHD Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase) pir||A83858 histidinol-phosphate aminotransferase/tyrosine and phenylalanine aminotransferase hisC [imported] - Bacillus halodurans (strain C-125) dbj|BAB05384.1| histidinol-phosphate aminotransferase [Bacillus halodurans] Length = 369 Score = 360 bits (923), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 178/354 (50%), Positives = 234/354 (66%), Gaps = 1/354 (0%) Query: 1 MNPKPNIVNLPVYKPGKPIEEVKKELGLNDVIKLASNENPYGSSPSAKAAILAELDNLYL 60 M KP I+ LP YKPGKP+E+VK+ELGL V+KLASNENP+G+SP AI L + + Sbjct: 1 MKIKPQIIGLPPYKPGKPMEDVKRELGLETVVKLASNENPFGASPKVAEAIQEALHHTAI 60 Query: 61 YPDGSAAELTSALAGHLGVQSGNIIFGCGSDEIIALIARAFFLPGDETIMADQTFSVYKS 120 YPDG A L +A ++GV +IFG GSDE+I ++ RAF T+MA+ TFS YK Sbjct: 61 YPDGYARTLRDKVAHYVGVAPEELIFGNGSDEVIQILCRAFLNEQTNTVMAEPTFSQYKL 120 Query: 121 NADIEGAVSIEVPLADGTHDLDAMLARVTERTKVIWICNPNNPTGTIVPEEALITFLNAV 180 NA IEGA EVPL DG HDLD ML + E T+++W+CNPNNPTGT V EA +FL V Sbjct: 121 NAVIEGAELREVPLKDGVHDLDGMLEVIDENTRIVWVCNPNNPTGTYVSAEAFQSFLAKV 180 Query: 181 PSGVMVVLDEAYCEYVTDLSYSNGIKLLESYPNLVVLRTFSKIYGLAALRIGYGVASPQI 240 P V+VV DEAY EYVT Y + + ++ +Y NLVVLRTFSK++GLAALRIGYGVA+ + Sbjct: 181 PEDVLVVSDEAYVEYVTADDYPDTVPMIRTYKNLVVLRTFSKVFGLAALRIGYGVANQAL 240 Query: 241 ISLINKVREPFNTSRXXXXXXXXXXXDQEYVQECRRLNSAGILQLQAEFKRLDLAFFPAH 300 I I VR PFN S D+ +VQ N+ G+ QL R+ L +FP+ Sbjct: 241 IEKIEPVRPPFNNSTFSQVAAVAALEDEAFVQSSVEKNNEGMEQLTEWCSRMGLDYFPSQ 300 Query: 301 GNFIMVDVRRPAADIFDALLRRGIIVRAGHKL-YPTYIRVTVGSAEQNKAFIAA 353 NF+++ V R + D+F+A+L++G I+R+G L YP +IR+T+GS EQN +AA Sbjct: 301 TNFLLIHVNRSSDDVFNAMLKKGYIIRSGRALGYPAWIRITIGSKEQNDGCLAA 354 >dbj|BAC11847.1| histidinol-phosphate aminotransferase [Bacillus subtilis] Length = 360 Score = 350 bits (898), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 180/354 (50%), Positives = 231/354 (65%), Gaps = 2/354 (0%) Query: 1 MNPKPNIVNLPVYKPGKPIEEVKKELGLNDVIKLASNENPYGSSPSAKAAILAELDNLYL 60 M K ++ L Y+PGKPIE VK E GL+ V+KLASNENPYG S +AK A+ E+ L L Sbjct: 1 MRIKEHLKQLKPYQPGKPIEAVKSEYGLDKVVKLASNENPYGCSEAAKEALHHEIQQLAL 60 Query: 61 YPDGSAAELTSALAGHLGVQSGNIIFGCGSDEIIALIARAFFLPGDETIMADQTFSVYKS 120 YPDG +A L + L+ HL V ++IFG GSDEII +I RAF TI A TF YK Sbjct: 61 YPDGYSAALRTRLSKHLNVSETSLIFGNGSDEIIQIICRAFLNNKTNTITAAPTFPQYKH 120 Query: 121 NADIEGAVSIEVPLA-DGTHDLDAMLARVTERTKVIWICNPNNPTGTIVPEEALITFLNA 179 NA IEGA E+ L DG+HDLDAML + E+T+V+WIC+PNNPTGT E L+ FL Sbjct: 121 NAVIEGAEVREIALRPDGSHDLDAMLEAIDEQTQVVWICSPNNPTGTYTSEGELLAFLER 180 Query: 180 VPSGVMVVLDEAYCEYVTDLSYSNGIKLLESYPNLVVLRTFSKIYGLAALRIGYGVASPQ 239 VPS V+VVLDEAY EYVT Y + LL Y NL++LRTFSK YGLAALR+GYG+A Sbjct: 181 VPSRVLVVLDEAYYEYVTAEDYPETVPLLSKYSNLMILRTFSKAYGLAALRVGYGIADEN 240 Query: 240 IISLINKVREPFNTSRXXXXXXXXXXXDQEYVQECRRLNSAGILQLQAEFKRLDLAFFPA 299 +I I REPFNTSR DQ ++ C N+AG+ Q K L +P+ Sbjct: 241 LIRQIEPAREPFNTSRLGQAAAIAALDDQAFIASCVEQNNAGLQQYYDFAKTHGLKCYPS 300 Query: 300 HGNFIMVDVRRPAADIFDALLRRGIIVRAGHKL-YPTYIRVTVGSAEQNKAFIA 352 NF+++D +RPA ++F ALL +G IVR+G+ L +PT +R+T+G+ EQN+ +A Sbjct: 301 QTNFVLIDFKRPADELFQALLEKGYIVRSGNALGFPTSLRITIGTKEQNEEILA 354 >ref|NP_390143.1| histidinol-phosphate aminotransferase; tyrosine/phenylalanine aminotransferase [Bacillus subtilis] sp|P17731|HIS8_BACSU Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase) pir||A26532 histidinol-phosphate transaminase (EC 2.6.1.9) / tyrosine and phenylalanine aminotransferase hisC - Bacillus subtilis gb|AAA20867.1| HisH [Bacillus subtilis] emb|CAB14178.1| histidinol-phosphate aminotransferase; tyrosine/phenylalanine aminotransferase [Bacillus subtilis subsp. subtilis str. 168] Length = 360 Score = 350 bits (897), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 179/354 (50%), Positives = 231/354 (65%), Gaps = 2/354 (0%) Query: 1 MNPKPNIVNLPVYKPGKPIEEVKKELGLNDVIKLASNENPYGSSPSAKAAILAELDNLYL 60 M K ++ L Y+PGKPIE VK E GL+ V+KLASNENPYG S +AK A+ E+ L L Sbjct: 1 MRIKEHLKQLKPYQPGKPIEAVKSEYGLDKVVKLASNENPYGCSEAAKEALHHEIQQLAL 60 Query: 61 YPDGSAAELTSALAGHLGVQSGNIIFGCGSDEIIALIARAFFLPGDETIMADQTFSVYKS 120 YPDG +A L + L+ HL V ++IFG GSDEII +I RAF T+ A TF YK Sbjct: 61 YPDGYSAALRTRLSKHLNVSETSLIFGNGSDEIIQIICRAFLNDKTNTVTAAPTFPQYKH 120 Query: 121 NADIEGAVSIEVPLA-DGTHDLDAMLARVTERTKVIWICNPNNPTGTIVPEEALITFLNA 179 NA IEGA E+ L DG+HDLDAML + E+T+V+WIC+PNNPTGT E L+ FL Sbjct: 121 NAVIEGAEVREIALRPDGSHDLDAMLEAIDEQTQVVWICSPNNPTGTYTSEGELLAFLER 180 Query: 180 VPSGVMVVLDEAYCEYVTDLSYSNGIKLLESYPNLVVLRTFSKIYGLAALRIGYGVASPQ 239 VPS V+VVLDEAY EYVT Y + LL Y NL++LRTFSK YGLAALR+GYG+A Sbjct: 181 VPSRVLVVLDEAYYEYVTAEDYPETVPLLSKYSNLMILRTFSKAYGLAALRVGYGIADEN 240 Query: 240 IISLINKVREPFNTSRXXXXXXXXXXXDQEYVQECRRLNSAGILQLQAEFKRLDLAFFPA 299 +I I REPFNTSR DQ ++ C N+AG+ Q K L +P+ Sbjct: 241 LIRQIEPAREPFNTSRLGQAAAIAALYDQAFIASCVEQNNAGLQQYYDFAKTHGLKCYPS 300 Query: 300 HGNFIMVDVRRPAADIFDALLRRGIIVRAGHKL-YPTYIRVTVGSAEQNKAFIA 352 NF+++D +RPA ++F ALL +G IVR+G+ L +PT +R+T+G+ EQN+ +A Sbjct: 301 QTNFVLIDFKRPADELFQALLEKGYIVRSGNALGFPTSLRITIGTKEQNEEILA 354 >ref|NP_977966.1| histidinol-phosphate aminotransferase [Bacillus cereus ATCC 10987] gb|AAS40574.1| histidinol-phosphate aminotransferase [Bacillus cereus ATCC 10987] Length = 370 Score = 323 bits (829), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 161/352 (45%), Positives = 220/352 (62%), Gaps = 1/352 (0%) Query: 1 MNPKPNIVNLPVYKPGKPIEEVKKELGLNDVIKLASNENPYGSSPSAKAAILAELDNLYL 60 M K ++ L Y PGK IEEVK+E GL+ ++KLASNENP+G S A+ + L Sbjct: 1 MRVKEQLLTLRAYVPGKNIEEVKREYGLSKIVKLASNENPFGCSARVTEALTSLASQYAL 60 Query: 61 YPDGSAAELTSALAGHLGVQSGNIIFGCGSDEIIALIARAFFLPGDETIMADQTFSVYKS 120 YPDG A EL + +A HLGV++ ++FG G DE+I +I+RA G +MA+ TFS Y Sbjct: 61 YPDGYAFELRTKVAEHLGVKAEQLLFGSGLDEVIQMISRALLHEGTNVVMANPTFSQYHH 120 Query: 121 NADIEGAVSIEVPLADGTHDLDAMLARVTERTKVIWICNPNNPTGTIVPEEALITFLNAV 180 +A IEGA EVPL DG HDLDAML +V ++TK++WICNPNNPTGT V ++ L++FL +V Sbjct: 121 HAVIEGAKVREVPLKDGIHDLDAMLEQVDDKTKIVWICNPNNPTGTYVEKQKLLSFLESV 180 Query: 181 PSGVMVVLDEAYCEYVTDLSYSNGIKLLESYPNLVVLRTFSKIYGLAALRIGYGVASPQI 240 P +V++DEAY EY Y + LLE Y NL++LRTFSK YGLAA RIGY V + Q+ Sbjct: 181 PKSALVIMDEAYYEYAGAEDYPQTLPLLEKYGNLMILRTFSKAYGLAAFRIGYAVGNEQL 240 Query: 241 ISLINKVREPFNTSRXXXXXXXXXXXDQEYVQECRRLNSAGILQLQAEFKRLDLAFFPAH 300 I + R PFNTS DQ ++QEC + N G+ Q A K ++ ++P+ Sbjct: 241 IGQLEVARLPFNTSTVAQSVALAALEDQAFLQECVKKNEEGLHQYYAFCKEYNVFYYPSQ 300 Query: 301 GNFIMVDVRRPAADIFDALLRRGIIVRAGHKL-YPTYIRVTVGSAEQNKAFI 351 NFI + + P + F+ L+++G IVR+G IR+TVG E+N I Sbjct: 301 TNFIFLKLGIPGNEAFERLMKKGYIVRSGAAFGIHDGIRITVGLKEENDEII 352 >ref|NP_655419.1| aminotran_1_2, Aminotransferase class I and II [Bacillus anthracis A2012] ref|NP_843990.1| histidinol-phosphate aminotransferase [Bacillus anthracis str. Ames] sp|Q81SV5|HI81_BACAA Histidinol-phosphate aminotransferase 1 (Imidazole acetol-phosphate transaminase 1) gb|AAP25476.1| histidinol-phosphate aminotransferase [Bacillus anthracis str. Ames] Length = 370 Score = 321 bits (822), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 160/352 (45%), Positives = 219/352 (62%), Gaps = 1/352 (0%) Query: 1 MNPKPNIVNLPVYKPGKPIEEVKKELGLNDVIKLASNENPYGSSPSAKAAILAELDNLYL 60 M K ++ L Y PGK IEEVK+E GL+ ++KLASNENP+G S A+ + L Sbjct: 1 MRVKEQLLTLRAYVPGKNIEEVKREYGLSKIVKLASNENPFGCSARVTEALTSLASQYAL 60 Query: 61 YPDGSAAELTSALAGHLGVQSGNIIFGCGSDEIIALIARAFFLPGDETIMADQTFSVYKS 120 YPDG A EL + +A HLGV++ ++FG G DE+I +I+RA G +MA+ TFS Y Sbjct: 61 YPDGHAFELRTQVAKHLGVKAEQLLFGSGLDEVIQMISRALLHEGTNVVMANPTFSQYHH 120 Query: 121 NADIEGAVSIEVPLADGTHDLDAMLARVTERTKVIWICNPNNPTGTIVPEEALITFLNAV 180 +A IEGA EV L DG HDLDAML +V ++TK++WICNPNNPTGT V ++ L++FL +V Sbjct: 121 HAVIEGAEVREVSLKDGIHDLDAMLQQVDDQTKIVWICNPNNPTGTYVEKQKLLSFLESV 180 Query: 181 PSGVMVVLDEAYCEYVTDLSYSNGIKLLESYPNLVVLRTFSKIYGLAALRIGYGVASPQI 240 P +V++DEAY EY Y + LLE Y NL+VLRTFSK YGLAA RIGY V + ++ Sbjct: 181 PKSALVIMDEAYYEYAGAEDYPQTLPLLEKYENLMVLRTFSKAYGLAAFRIGYAVGNTEL 240 Query: 241 ISLINKVREPFNTSRXXXXXXXXXXXDQEYVQECRRLNSAGILQLQAEFKRLDLAFFPAH 300 I + R PFNTS DQ ++QEC + N G+ Q A K ++ ++P+ Sbjct: 241 IGQLEVARLPFNTSTVAQSVALAALEDQAFLQECVKKNEEGLHQYYAFCKEYNVFYYPSQ 300 Query: 301 GNFIMVDVRRPAADIFDALLRRGIIVRAGHKL-YPTYIRVTVGSAEQNKAFI 351 NFI + + P + F+ L+++G IVR+G IR+TVG E+N I Sbjct: 301 TNFIFLKLGIPGNEAFERLMKKGYIVRSGAAFGIDDGIRITVGLKEENDEII 352 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.137 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 499,115,640 Number of extensions: 19746554 Number of successful extensions: 54488 Number of sequences better than 1.0e-05: 1609 Number of HSP's gapped: 52992 Number of HSP's successfully gapped: 1609 Length of query: 365 Length of database: 757,237,578 Length adjustment: 127 Effective length of query: 238 Effective length of database: 412,420,005 Effective search space: 98155961190 Effective search space used: 98155961190 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 126 (53.1 bits)