BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0254.0021.p (207 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_832904.1| Transcriptional regulator, TetR family [Bacillu... 284 9e-76 ref|NP_657166.1| tetR, Bacterial regulatory proteins, tetR famil... 275 5e-73 ref|NP_388413.1| similar to transcriptional regulator (TetR/AcrR... 267 1e-70 ref|NP_350067.1| Transcriptional regulator, AcrR family [Clostri... 246 2e-64 ref|NP_926116.1| TetR family transcriptional regulatory protein ... 137 2e-31 >ref|NP_832904.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP10105.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 192 Score = 284 bits (727), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 134/190 (70%), Positives = 160/190 (84%) Query: 17 MDKKRGRPRNNEAEAAILAASYDLLLETGFGAVTVEKIAERAKVSKATIYKWWPNKAAVV 76 M KRGRPRN E + AIL+ASY+LLLE+GF AVTV+KIAERAKVSKATIYKWWPNKAAVV Sbjct: 1 MQSKRGRPRNIETQKAILSASYELLLESGFKAVTVDKIAERAKVSKATIYKWWPNKAAVV 60 Query: 77 IDGYLSAATARLPVPDTGSVKEDIRIHATNLAAFLYSREGKVITEMIGEGQFDAGLAEAY 136 +DG+LSAA ARLPVPDTGS DI IHAT+LA FL SREG +I E++GEGQFD+ LAE Y Sbjct: 61 MDGFLSAAAARLPVPDTGSALNDILIHATSLANFLISREGTIINELVGEGQFDSKLAEEY 120 Query: 137 RTRFFAPRRQEARQLLERGVMRGELKKDLDVNCSIDLMYGPIFYRLLITGDTLNGEFVEK 196 R R+F PRR +A+QLLE+G+ RGELK++LD+ SIDL+YGPIFYRLL+TG+ L+ +V Sbjct: 121 RVRYFQPRRLQAKQLLEKGIKRGELKENLDIELSIDLIYGPIFYRLLVTGEKLDDSYVHD 180 Query: 197 LLALAFEGIR 206 L+ AFEGIR Sbjct: 181 LVINAFEGIR 190 >ref|NP_657166.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_845593.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP27079.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 191 Score = 275 bits (703), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 133/190 (70%), Positives = 159/190 (83%), Gaps = 1/190 (0%) Query: 17 MDKKRGRPRNNEAEAAILAASYDLLLETGFGAVTVEKIAERAKVSKATIYKWWPNKAAVV 76 M KRGRPRN E + AIL+ASY+LLLE+GF AVTV+KIA+RAKVSKATIYKWWPNKAAVV Sbjct: 1 MQGKRGRPRNIETQKAILSASYELLLESGFKAVTVDKIADRAKVSKATIYKWWPNKAAVV 60 Query: 77 IDGYLSAATARLPVPDTGSVKEDIRIHATNLAAFLYSREGKVITEMIGEGQFDAGLAEAY 136 +DG+LSAA ARLPVPDTGS DI HAT+LA FL SREG +I E++GEGQFD+ LAE Y Sbjct: 61 MDGFLSAA-ARLPVPDTGSALNDILTHATSLANFLISREGTIINELVGEGQFDSKLAEEY 119 Query: 137 RTRFFAPRRQEARQLLERGVMRGELKKDLDVNCSIDLMYGPIFYRLLITGDTLNGEFVEK 196 R R+F PRR +A+QLLE+G+ RGELK++LDV SIDL+YGPIFYRLL+TG+ L+ +V Sbjct: 120 RARYFQPRRLQAKQLLEKGMKRGELKENLDVELSIDLIYGPIFYRLLVTGEKLDDSYVHD 179 Query: 197 LLALAFEGIR 206 L+ AFEGIR Sbjct: 180 LVINAFEGIR 189 >ref|NP_388413.1| similar to transcriptional regulator (TetR/AcrR family) [Bacillus subtilis] pir||E69779 transcription regulator TetR/AcrR family homolog ydeS - Bacillus subtilis dbj|BAA19366.1| PROBABLE TRANSCRIPTIONAL REGULATOR, SIMILAR TO REGULATOR OF ANTIBIOTIC TRANSPORT COMPLEXES IN STREPTOMYCES HYGROSCOPICUS. [Bacillus subtilis] emb|CAB12339.1| ydeS [Bacillus subtilis subsp. subtilis str. 168] Length = 198 Score = 267 bits (682), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 127/191 (66%), Positives = 152/191 (79%) Query: 17 MDKKRGRPRNNEAEAAILAASYDLLLETGFGAVTVEKIAERAKVSKATIYKWWPNKAAVV 76 M KRGRPR+ AIL+A+YDLLLE GF AVTV+KIAERAKVSKATIYKWW NKAAV+ Sbjct: 1 MQSKRGRPRDEGTHKAILSAAYDLLLEKGFDAVTVDKIAERAKVSKATIYKWWSNKAAVI 60 Query: 77 IDGYLSAATARLPVPDTGSVKEDIRIHATNLAAFLYSREGKVITEMIGEGQFDAGLAEAY 136 +D +LS AT RLPVPDTGS +DI HATNLA FL SREG VI E+IG GQ D LAE Y Sbjct: 61 MDSFLSTATDRLPVPDTGSSVQDIVTHATNLARFLTSREGTVIKELIGAGQLDEKLAEEY 120 Query: 137 RTRFFAPRRQEARQLLERGVMRGELKKDLDVNCSIDLMYGPIFYRLLITGDTLNGEFVEK 196 RTRFF PRR +A+ LLE+G+ +GEL+++LD+ SIDL+YGPIFYRLLITGD +N +V Sbjct: 121 RTRFFQPRRLQAKGLLEKGIQKGELRENLDIEVSIDLIYGPIFYRLLITGDEVNDSYVRD 180 Query: 197 LLALAFEGIRA 207 L+ AF+G++A Sbjct: 181 LVMNAFKGVQA 191 >ref|NP_350067.1| Transcriptional regulator, AcrR family [Clostridium acetobutylicum] pir||D97327 transcription regulator, AcrR family [imported] - Clostridium acetobutylicum gb|AAK81407.1| Transcriptional regulator, AcrR family [Clostridium acetobutylicum] Length = 192 Score = 246 bits (628), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 111/190 (58%), Positives = 148/190 (77%) Query: 17 MDKKRGRPRNNEAEAAILAASYDLLLETGFGAVTVEKIAERAKVSKATIYKWWPNKAAVV 76 MDKK GRPR+ + ++ IL A+Y+LL+E GF +TVEKIAERA VSKATIYKWWPNKAAV+ Sbjct: 1 MDKKLGRPRSEKTKSDILNAAYELLIENGFAEITVEKIAERANVSKATIYKWWPNKAAVI 60 Query: 77 IDGYLSAATARLPVPDTGSVKEDIRIHATNLAAFLYSREGKVITEMIGEGQFDAGLAEAY 136 IDG+L+ LP+PDTGS +D+ I N FL SR+G VITE+I EGQ+D LA+ Y Sbjct: 61 IDGFLNTTNVELPIPDTGSTIQDMFIQVDNFTKFLTSRKGSVITEIIAEGQYDPKLADIY 120 Query: 137 RTRFFAPRRQEARQLLERGVMRGELKKDLDVNCSIDLMYGPIFYRLLITGDTLNGEFVEK 196 R +F PRR ++++LERG++RGELKKDL++ IDL++GPIFYRLLITG+ ++ FV++ Sbjct: 121 RKAYFTPRRSISKKILERGILRGELKKDLNIEVIIDLIWGPIFYRLLITGEKIDVAFVKE 180 Query: 197 LLALAFEGIR 206 ++ AFEGI+ Sbjct: 181 IINYAFEGIK 190 >ref|NP_926116.1| TetR family transcriptional regulatory protein [Gloeobacter violaceus] dbj|BAC91111.1| TetR family transcriptional regulatory protein [Gloeobacter violaceus PCC 7421] Length = 196 Score = 137 bits (344), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 74/189 (39%), Positives = 110/189 (58%) Query: 18 DKKRGRPRNNEAEAAILAASYDLLLETGFGAVTVEKIAERAKVSKATIYKWWPNKAAVVI 77 +K+ GRPR+ E+ AAIL A++ LL T +++E IA + V KATIY+WWP+KAAV I Sbjct: 6 EKRVGRPRSAESRAAILNATWTLLKTTTLRDLSIEAIAHESGVGKATIYRWWPSKAAVAI 65 Query: 78 DGYLSAATARLPVPDTGSVKEDIRIHATNLAAFLYSREGKVITEMIGEGQFDAGLAEAYR 137 D +L P P+ S E I +L G+++ ++I EGQ D YR Sbjct: 66 DAFLENVLLVTPYPEGLSATEAIARQMASLVQAWSGEYGRILAQVIAEGQADPEALNNYR 125 Query: 138 TRFFAPRRQEARQLLERGVMRGELKKDLDVNCSIDLMYGPIFYRLLITGDTLNGEFVEKL 197 R+ RR EA+ +++RG+ GE DLD + +ID++YGPI+YRLL+ L+ F +L Sbjct: 126 ARYLNHRRAEAKAVIQRGIKDGEFAPDLDPDLAIDILYGPIYYRLLVGHLPLDQRFATEL 185 Query: 198 LALAFEGIR 206 A + +R Sbjct: 186 SQWALQALR 194 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.137 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 281,976,486 Number of extensions: 10798342 Number of successful extensions: 28579 Number of sequences better than 1.0e-05: 63 Number of HSP's gapped: 28554 Number of HSP's successfully gapped: 63 Length of query: 207 Length of database: 757,237,578 Length adjustment: 120 Effective length of query: 87 Effective length of database: 431,425,698 Effective search space: 37534035726 Effective search space used: 37534035726 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 123 (52.0 bits)