BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0254.0001.p (202 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_976830.1| transcriptional regulator, TetR family [Bacillu... 135 8e-31 ref|NP_830272.1| Transcriptional regulator, TetR family [Bacillu... 133 2e-30 ref|NP_654324.1| tetR, Bacterial regulatory proteins, tetR famil... 133 3e-30 ref|NP_978986.1| transcriptional regulator, TetR family domain p... 79 4e-14 gb|AAC38779.1| transcriptional regulator QacR [Staphylococcus au... 75 6e-13 >ref|NP_976830.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS39438.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 193 Score = 135 bits (339), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 71/195 (36%), Positives = 113/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I KA LF QKGY A +M E+C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK +S S E+ Y L E++ D Q P+ A+EE++ ++ S E+ L Sbjct: 62 HTYDWLEKWNEKEKSYSTNTEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILDELL 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L + L++ G+ SG + + + + +V+GLL G+ ++ +++ + Sbjct: 122 ALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVNGLLSGLG----VLYYELDYKELKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LL+G+ A Sbjct: 178 IYKKAIDVLLKGMAA 192 >ref|NP_830272.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP07473.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 193 Score = 133 bits (335), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 70/195 (35%), Positives = 113/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I KA LF QKGY A +M E+C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK + S E+ Y L E++ D Q P+ A+EE++ ++ S E+ + L Sbjct: 62 HTYDWLEKWNEKEKLYSTSTEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILEELL 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L + L++ G+ SG + + + + +V+GLL G+ ++ +++ + Sbjct: 122 ALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVNGLLSGLG----VLYYELDYKELKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LL+G+ A Sbjct: 178 IYKKAIDVLLKGMAA 192 >ref|NP_654324.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_842933.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP24419.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 193 Score = 133 bits (334), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 70/195 (35%), Positives = 113/195 (57%), Gaps = 4/195 (2%) Query: 7 RSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVED 66 R EE KK I KA LF QKGY A +M E+C + SKGS+Y+HF SK+ELFL+VV+ Sbjct: 2 RRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQ 61 Query: 67 DTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQRLA 126 T WL +W EK + S E+ YAL E++ D Q P+ A+EE++ ++ S E+ + Sbjct: 62 HTYDWLEKWNEKEKLYSTSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEML 121 Query: 127 QLYESASEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVSEIMAAAKAPEDIMQ 186 L + L++ G+ SG + + + + +V+GLL G+ ++ +++ + Sbjct: 122 ALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLLSGLG----VLYYELDYKELKR 177 Query: 187 YYREAIGLLLQGIRA 201 Y++AI +LL+G+ A Sbjct: 178 IYKKAIDVLLKGMAA 192 >ref|NP_978986.1| transcriptional regulator, TetR family domain protein [Bacillus cereus ATCC 10987] gb|AAS41594.1| transcriptional regulator, TetR family domain protein [Bacillus cereus ATCC 10987] Length = 198 Score = 79.3 bits (194), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 41/143 (28%), Positives = 75/143 (52%) Query: 5 KGRSDGEETKKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVV 64 K R D + K+ I +KA +LF KGY +++ + A+ SKG +Y+H+ +K+ELF+Y+ Sbjct: 3 KRRYDSDLAKEIIAEKATELFSLKGYTRTSIDNIAKASGYSKGHIYYHYKNKEELFVYLA 62 Query: 65 EDDTEQWLSQWAEKSRSISGLEERFYALGEHYANDFQNPLIRALEEYARARPHSDEVHQR 124 +D W +W + + + Y + + +++ PL+RA +E A + Q+ Sbjct: 63 KDSMRNWHDKWEIAEKQYTNATGKLYGIAKFVLYNYKTPLLRAGQELASDPSANPSTIQQ 122 Query: 125 LAQLYESASEACRNLLQEGMDSG 147 L L + + +L EG+ SG Sbjct: 123 LYGLAVIPLKTYQKILDEGIQSG 145 >gb|AAC38779.1| transcriptional regulator QacR [Staphylococcus aureus] gb|AAC38783.1| transcriptional regulator QacR [Staphylococcus aureus] gb|AAK38456.1| repressor QacR [Staphylococcus epidermidis] gb|AAM97340.1| transcriptional regulator QacR [Staphylococcus epidermidis] Length = 188 Score = 75.5 bits (184), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 39/160 (24%), Positives = 81/160 (50%), Gaps = 1/160 (0%) Query: 14 KKRIVQKAAQLFVQKGYGAVTMNEVCSAAKVSKGSLYHHFPSKDELFLYVVEDDTEQWLS 73 K +I+ A +LF++ GY A T E+ ++ SKG+LY+HF +K+ LFL ++ + +W Sbjct: 4 KDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFLEILNIEESKWQE 63 Query: 74 QWAEKSRSISGLEERFYALGE-HYANDFQNPLIRALEEYARARPHSDEVHQRLAQLYESA 132 QW ++ E+FY E ++ PL A+ E+ ++ +++++ +L Sbjct: 64 QWKKEQIKCKTNREKFYLYNELSLTTEYYYPLQNAIIEFCTEYYKTNSINEKMNKLENKY 123 Query: 133 SEACRNLLQEGMDSGYLVKGDLDNYVIVVSGLLEGVARVS 172 +A + +EG +G D++ + + + G+ + Sbjct: 124 IDAYHVIFKEGNLNGEWCINDVNAVSKIAANAVNGIVTFT 163 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.133 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 284,504,069 Number of extensions: 10745594 Number of successful extensions: 34627 Number of sequences better than 1.0e-05: 147 Number of HSP's gapped: 34675 Number of HSP's successfully gapped: 147 Length of query: 202 Length of database: 757,237,578 Length adjustment: 120 Effective length of query: 82 Effective length of database: 431,425,698 Effective search space: 35376907236 Effective search space used: 35376907236 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 123 (52.0 bits)