BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0247.0016.p (479 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_390192.1| two-component sensor histidine kinase [Bacillus... 383 e-105 ref|NP_242447.1| two-component sensor histidine kinase [Bacillus... 354 3e-96 ref|NP_692739.1| two-component sensor histidine kinase [Oceanoba... 346 8e-94 ref|NP_831257.1| Sensor protein resE [Bacillus cereus ATCC 14579... 332 1e-89 ref|NP_471395.1| similar to two-component sensor histidine kinas... 331 2e-89 >ref|NP_390192.1| two-component sensor histidine kinase [Bacillus subtilis] sp|P35164|RESE_BACSU Sensor protein resE pir||H69691 two-component sensor histidine kinase resE - Bacillus subtilis gb|AAA67498.1| ORFX18 emb|CAB14243.1| two-component sensor histidine kinase [Bacillus subtilis subsp. subtilis str. 168] Length = 589 Score = 383 bits (984), Expect = e-105, Method: Compositional matrix adjust. Identities = 200/412 (48%), Positives = 283/412 (68%), Gaps = 27/412 (6%) Query: 73 PMQQVIEAADNIRRGEYGTRLTLVTSDEIGLLATSFNHMAEELEENIRSLNHEKGHLSSV 132 P++++ E A ++ +G++ T++ ++T DEIG LAT+FN M +L +I +LN EK LS++ Sbjct: 199 PLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQLNFHINALNQEKEQLSNI 258 Query: 133 LRSMSDAVLTFDIIGKIILTNPHGQALLERWNDLDWELENESELYPQGASDSE---VPPP 189 L SM+D V+T +I G I++TNP + L+ W Y Q + E +PP Sbjct: 259 LSSMADGVITINIDGTILVTNPPAERFLQAW------------YYEQNMNIKEGDNLPPE 306 Query: 190 LRPLFFSTLREGGDQRSQVHVRQGVWSVHMAPLYSEDTIRGVVAVLRDVTEEVKLEKMRR 249 + LF + + +Q ++ ++ W + M+PLY+E +RG VAVLRD+TEE +L+K+R Sbjct: 307 AKELFQNAVSTEKEQMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERRLDKLRE 366 Query: 250 DFVANVSHEIRTPLSMMQGYSEALLDGMASSPEESSELVQVIHDESLRMGRLVKDLLDLA 309 DF+ANVSHE+RTP+SM+QGYSEA++D +ASS E+ E+ Q+I+DESLRMGRLV DLLDLA Sbjct: 367 DFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIAQIIYDESLRMGRLVNDLLDLA 426 Query: 310 RMEAGHTDMMKVPVDMGELLERVYRKFSVRAKERGLQLELKSGSDTLLLKAA---DEDKL 366 RME+GHT + +++ E LE++ RKFS AKE+ + L+ D L + DEDK+ Sbjct: 427 RMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALD----HDISLTEEEFMFDEDKM 482 Query: 367 EQVLTNLLDNAFRHTPADKCITILTSTAVLEGRRYLEIAIRDEGVGIPPEDLPFIFERFY 426 EQV TNL+DNA RHT A ++I + +V +G L+I I+D G GIP EDLPFIFERFY Sbjct: 483 EQVFTNLIDNALRHTSAGGSVSI-SVHSVKDG---LKIDIKDSGSGIPEEDLPFIFERFY 538 Query: 427 KADKARVRGESGGTGLGLAIVKNIVEAHHGTITASSRLGEGTEFLLRLPVEK 478 KADKAR RG + GTGLGLAIVKNIVEAH+G+IT SR+ +GT F +P ++ Sbjct: 539 KADKARTRGRA-GTGLGLAIVKNIVEAHNGSITVHSRIDKGTTFSFYIPTKR 589 >ref|NP_242447.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83847 two-component sensor histidine kinase resE [imported] - Bacillus halodurans (strain C-125) dbj|BAB05300.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 594 Score = 354 bits (908), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 186/406 (45%), Positives = 263/406 (64%), Gaps = 20/406 (4%) Query: 73 PMQQVIEAADNIRRGEYGTRLTLVTSDEIGLLATSFNHMAEELEENIRSLNHEKGHLSSV 132 P++++ + A + +G++ T++ ++T DEIG LA +FN M EL N+ LN EK LS + Sbjct: 200 PLRKMRQVALEVAQGKFNTKVPILTHDEIGQLAIAFNRMRRELNRNVTELNQEKEQLSRI 259 Query: 133 LRSMSDAVLTFDIIGKIILTNPHGQALLERWNDLDWELENESELYPQG---ASDSEVPPP 189 L SM+D V+T D GK+++TNP + ++ W+ Y QG + +E+P Sbjct: 260 LSSMADGVITLDKRGKVMVTNPPAERFIQAWH------------YEQGLVPSEKNELPQA 307 Query: 190 LRPLFFSTLREGGDQRSQVHVRQGVWSVHMAPLYSEDTIRGVVAVLRDVTEEVKLEKMRR 249 + L+ + +Q +++ V+ W++ M PLY +RG VAV+RD+TEE + +K+R+ Sbjct: 308 IHQLYQQVVALESEQMTELDVQGRSWAILMTPLYDNSYVRGAVAVIRDMTEERRHDKLRK 367 Query: 250 DFVANVSHEIRTPLSMMQGYSEALLDGMASSPEESSELVQVIHDESLRMGRLVKDLLDLA 309 DF+ANVSHE+RTP+SM+QGYSEA++D +A + +E EL ++I+DESLRMGRLV +LLDLA Sbjct: 368 DFIANVSHELRTPISMLQGYSEAIIDDIAGTDQEKKELAKIIYDESLRMGRLVNELLDLA 427 Query: 310 RMEAGHTDMMKVPVDMGELLERVYRKFSVRAKERGLQLELKSGSDTLLLKAADEDKLEQV 369 RMEAGH D+ +++ ER+ RKF AKE+ L L+ D D D+LEQV Sbjct: 428 RMEAGHIDLSYEEIEVKTFCERITRKFQGLAKEQQLTLDFIYRGDEGKRIQVDPDRLEQV 487 Query: 370 LTNLLDNAFRHTPADKCITILTSTAVLEGRRYLEIAIRDEGVGIPPEDLPFIFERFYKAD 429 LTNLL NA RHT D T+ + V+E ++I + D G GIP EDLP++FERFYKAD Sbjct: 488 LTNLLSNAIRHT--DPGGTVQLACHVMENG--VKIDVTDTGTGIPEEDLPYVFERFYKAD 543 Query: 430 KARVRGESGGTGLGLAIVKNIVEAHHGTITASSRLGEGTEFLLRLP 475 KAR RG S GTGLGLAIVKNIV+AH G I+ S+ EGT F P Sbjct: 544 KARTRGRS-GTGLGLAIVKNIVDAHSGEISVHSKQQEGTTFTAFFP 588 >ref|NP_692739.1| two-component sensor histidine kinase [Oceanobacillus iheyensis HTE831] dbj|BAC13774.1| two-component sensor histidine kinase [Oceanobacillus iheyensis HTE831] Length = 584 Score = 346 bits (887), Expect = 8e-94, Method: Compositional matrix adjust. Identities = 185/410 (45%), Positives = 266/410 (64%), Gaps = 22/410 (5%) Query: 73 PMQQVIEAADNIRRGEYGTRLTLVTSDEIGLLATSFNHMAEELEENIRSLNHEKGHLSSV 132 P+ ++ EAA N+ RGE+ T++ ++T DEIG LA FN M +L +I +L EK LSS+ Sbjct: 192 PLIKMKEAAHNLTRGEFNTKVPVLTRDEIGELAIEFNRMGRQLNYHINALRQEKEQLSSI 251 Query: 133 LRSMSDAVLTFDIIGKIILTNPHGQALLERWNDLDWELENESELYPQGASDSEVPPPLRP 192 + SM+D V T + G++++ NP + ++ +W EN E Q +EV L Sbjct: 252 VSSMADGVFTLNREGEVLVINPPAKKYMD-----EWFYENPDESEGQNHLPTEVKEALLE 306 Query: 193 LF---FSTLREGGDQ-RSQVHVRQGVWSVHMAPLYSEDTIRGVVAVLRDVTEEVKLEKMR 248 + ++ L+E Q RS V + + PLY E +RG VAV+RD+TEE +L+K+R Sbjct: 307 VITKEYAVLKESAVQGRSYVML--------VTPLYDESHVRGCVAVIRDMTEERRLDKLR 358 Query: 249 RDFVANVSHEIRTPLSMMQGYSEALLDGMASSPEESSELVQVIHDESLRMGRLVKDLLDL 308 +DF+ANVSHE+RTP+SM+QGYSEA++D +ASS EE +EL Q+I++ESLRMGRLV +LLDL Sbjct: 359 KDFIANVSHELRTPISMLQGYSEAIVDDVASSKEEKNELAQIIYEESLRMGRLVNELLDL 418 Query: 309 ARMEAGHTDMMKVPVDMGELLERVYRKFSVRAKERGLQLELKSGSDTLLLKAADEDKLEQ 368 ARMEAG + V + +ER+ KF ++E ++LEL + + D D++EQ Sbjct: 419 ARMEAGQIQLRLDSVAIQPFIERIVHKFQGISREEMVELELTVDIEH-QIGEMDPDRIEQ 477 Query: 369 VLTNLLDNAFRHTPADKCITILTSTAVLEGRRYLEIAIRDEGVGIPPEDLPFIFERFYKA 428 VLTNL+DNA RHT + + +L + + L + ++D G GIP EDLPFIFERFYKA Sbjct: 478 VLTNLIDNAIRHTSNNGFVKVLA----VSNQDKLYVEVKDSGSGIPEEDLPFIFERFYKA 533 Query: 429 DKARVRGESGGTGLGLAIVKNIVEAHHGTITASSRLGEGTEFLLRLPVEK 478 DK+RV+ E GTGLGLAI KNI++AHHG+I S+L GT F +P+++ Sbjct: 534 DKSRVKKEKQGTGLGLAIAKNIIDAHHGSIYVKSKLDAGTTFSFEIPIKQ 583 >ref|NP_831257.1| Sensor protein resE [Bacillus cereus ATCC 14579] gb|AAP08458.1| Sensor protein resE [Bacillus cereus ATCC 14579] Length = 591 Score = 332 bits (851), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 183/405 (45%), Positives = 266/405 (65%), Gaps = 20/405 (4%) Query: 73 PMQQVIEAADNIRRGEYGTRLTLVTSDEIGLLATSFNHMAEELEENIRSLNHEKGHLSSV 132 P++++ E A + RG++ + +V+ DEIG LAT+ N M ++L+ N+ +L EK L+S+ Sbjct: 201 PLRKMREVAFEVSRGKFDAKAPMVSQDEIGELATALNQMGKQLKFNMNALQQEKEQLASI 260 Query: 133 LRSMSDAVLTFDIIGKIILTNPHGQALLERWNDLDWELENESELYPQGASDSEVPPPLRP 192 L SM+D V+T + G++++ NP + L+ W + E E EL ++P L Sbjct: 261 LSSMADGVITLNQEGEVVVINPPAEHFLQVWQE-----EKEIEL------SKKLPSELVE 309 Query: 193 LFFSTLREGGDQRSQVHVRQGVWSVHMAPLYSEDTIRGVVAVLRDVTEEVKLEKMRRDFV 252 LF + Q ++++++G + V M PLY++ IRG VAVLRD+TEE +LEKMR+DF+ Sbjct: 310 LFHLVVESEQQQVVEINLQKGNYVVLMTPLYNQTKIRGAVAVLRDMTEERRLEKMRQDFI 369 Query: 253 ANVSHEIRTPLSMMQGYSEALLDGMASSPEESSELVQVIHDESLRMGRLVKDLLDLARME 312 ANVSHE+RTP+ M+QGYSEA+LD + + EE E VQ+I+DES+R+G+LV +LLDLARME Sbjct: 370 ANVSHELRTPMVMLQGYSEAILDDIVQTKEEIDEFVQIIYDESVRLGKLVNELLDLARME 429 Query: 313 AGHTDMMKVPVDMGELLERVYRKFS--VRAKERGLQLELKSGSDTLLLKAADEDKLEQVL 370 +GH ++ VD+ +E++ RKF + KE L ++ K + D D++EQVL Sbjct: 430 SGHVELHIGEVDIHPFVEKIGRKFQGIAKDKEVALTVDFKGPIEQYPF---DADRMEQVL 486 Query: 371 TNLLDNAFRHTPADKCITILTSTAVLEGRRYLEIAIRDEGVGIPPEDLPFIFERFYKADK 430 TNL+DNA RHT A +T++ T L ++D G GIP ED+PF+F+RFYKADK Sbjct: 487 TNLIDNAIRHTNAGGHVTLVIDTK----NNGLIFEVQDSGAGIPEEDIPFLFDRFYKADK 542 Query: 431 ARVRGESGGTGLGLAIVKNIVEAHHGTITASSRLGEGTEFLLRLP 475 AR RG+ GGTGLGLAI KNIV+ H G I+ SS +GEGT F + LP Sbjct: 543 ARTRGKKGGTGLGLAIAKNIVQGHDGKISVSSVVGEGTTFSVYLP 587 >ref|NP_471395.1| similar to two-component sensor histidine kinase (ResE) [Listeria innocua] pir||AC1690 two-component sensor histidine kinase (ResE) homolog resE [imported] - Listeria innocua (strain Clip11262) emb|CAC97291.1| resE [Listeria innocua] Length = 596 Score = 331 bits (849), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 176/407 (43%), Positives = 252/407 (61%), Gaps = 13/407 (3%) Query: 73 PMQQVIEAADNIRRGEYGTRLTLVTSDEIGLLATSFNHMAEELEENIRSLNHEKGHLSSV 132 P++++ + A + +G + R+ T DEIG L +FN MA++L+ NI +L EK LS++ Sbjct: 202 PLREMKKIAIAVSKGNFDNRVPTYTHDEIGELGVAFNDMAKQLKYNISALRQEKEQLSNI 261 Query: 133 LRSMSDAVLTFDIIGKIILTNPHGQALLERWNDLDWELENESELYPQGASDSEVPPPLRP 192 L M+D V+ F + IIL+NP + L W P+ +P L Sbjct: 262 LVGMADGVIKFSVDKTIILSNPPAEEFLHNW-----------FFSPENTEKVLIPTALND 310 Query: 193 LFFSTLREGGDQRSQVHVRQGVWSVHMAPLYSEDTIRGVVAVLRDVTEEVKLEKMRRDFV 252 L TL + Q ++ + + LY+ + +R +VAV+RD+TEE +LEKM+ DFV Sbjct: 311 LLNDTLDKKESQVGEITFSDRTYVAILTLLYTGEHVRSIVAVIRDMTEEKQLEKMKSDFV 370 Query: 253 ANVSHEIRTPLSMMQGYSEALLDGMASSPEESSELVQVIHDESLRMGRLVKDLLDLARME 312 NVSHE+RTP+SM+QGYSEA++DG+A S EE E Q+I+DESLR+GRLV D+LDLARME Sbjct: 371 NNVSHELRTPISMLQGYSEAIIDGVAQSDEEVREFAQIIYDESLRIGRLVNDMLDLARME 430 Query: 313 AGHTDMMKVPVDMGELLERVYRKFSVRAKERGLQLELKSGSDTLLLKAADEDKLEQVLTN 372 AG M + + LL +V F V AKE ++L L+ + L + D D++EQVL N Sbjct: 431 AGFNQMDNQKLPLAPLLRKVIANFDVLAKENFVELGLELETPDLEY-SYDPDRMEQVLIN 489 Query: 373 LLDNAFRHTPADKCI-TILTSTAVLEGRRYLEIAIRDEGVGIPPEDLPFIFERFYKADKA 431 L+ NA RHT + ++ + E R L I + D G GI ED+P++FERFYK DKA Sbjct: 490 LIMNAIRHTGKEGYAGKVILKQTIDETRNNLVITVSDNGSGIAEEDIPYLFERFYKVDKA 549 Query: 432 RVRGESGGTGLGLAIVKNIVEAHHGTITASSRLGEGTEFLLRLPVEK 478 R RG++ GTG+GLAIVKNIVEAH+G I+ S LG+G++F++ LP+ K Sbjct: 550 RKRGKAVGTGIGLAIVKNIVEAHNGKISVESVLGKGSDFIITLPLYK 596 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 644,857,222 Number of extensions: 25452874 Number of successful extensions: 103759 Number of sequences better than 1.0e-05: 5603 Number of HSP's gapped: 91626 Number of HSP's successfully gapped: 5651 Length of query: 479 Length of database: 757,237,578 Length adjustment: 129 Effective length of query: 350 Effective length of database: 406,989,807 Effective search space: 142446432450 Effective search space used: 142446432450 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 128 (53.9 bits)