BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0247.0007.p (287 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_925301.1| probable oxidoreductase [Gloeobacter violaceus]... 262 7e-69 ref|NP_625043.1| putative oxidoreductase [Streptomyces coelicolo... 213 6e-54 gb|AAS69752.1| oxidoreductase [Leptospira interrogans serovar Co... 212 7e-54 ref|ZP_00057549.1| COG1028: Dehydrogenases with different specif... 210 3e-53 ref|NP_241276.1| BH0410~unknown conserved protein in others [Bac... 207 2e-52 >ref|NP_925301.1| probable oxidoreductase [Gloeobacter violaceus] dbj|BAC90296.1| glr2355 [Gloeobacter violaceus PCC 7421] Length = 282 Score = 262 bits (669), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 145/282 (51%), Positives = 185/282 (65%), Gaps = 12/282 (4%) Query: 7 MTNLQGKVALVTGGSRGAGRGIALELAKAGAYVYITGRS-RGLSQED-RRKGTIDSVLDE 64 M L G+VA+VTG SRGAGRGIAL L GA VY+TGR+ RG S GTI+ + Sbjct: 1 MGLLSGRVAVVTGASRGAGRGIALALGDTGATVYVTGRTVRGGSLPFIGAPGTIEDTAEG 60 Query: 65 IRAAGGEGEAVRCDHTRDSETEAVIGRISSEQGRLDILVNNVWGGNERSIASKPFWELPT 124 + A GG G AVRCDHT D ++ A+ R++ EQGRLD+LVNN WGGNE S A PFWE P Sbjct: 61 VTARGGRGIAVRCDHTDDIQSAALFERVAHEQGRLDLLVNNAWGGNEGSFAEVPFWEEPL 120 Query: 125 DHWSHMFDAGVRAQLMTNYYAVPLMRSNREGGGIIIHTTYWDHYKYIDNFYYDLAKNALV 184 +W MF AGVRA L + +AVP+M + G G+I+ TT++D ++I N YYDLAK ++ Sbjct: 121 TNWDCMFTAGVRAHLAASRFAVPVML--KAGCGLIVCTTFYDEGRFIGNLYYDLAKASIN 178 Query: 185 RMAFGLSVELAADKIAVIPLSPGWMRTELVLESLNTDEEHWQDVAELQTSESTAYIGRAV 244 R+AFGL+ +L IA + LSPG+MRTELVL ++ D + V E EST YIGRAV Sbjct: 179 RLAFGLACQLRPHGIAAVALSPGFMRTELVL--MHPDPQ----VGE--PGESTEYIGRAV 230 Query: 245 VRLAADPEVLAMTGIPQQVGSLAEKYGFTDVDGRLVPVFKVP 286 LAADP +L +G VG LA +YG D+DG P F++P Sbjct: 231 AALAADPHILERSGRVLVVGELAREYGLCDIDGSQPPPFRLP 272 >ref|NP_625043.1| putative oxidoreductase [Streptomyces coelicolor A3(2)] emb|CAC14941.1| putative oxidoreductase [Streptomyces coelicolor A3(2)] Length = 308 Score = 213 bits (541), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 122/279 (43%), Positives = 164/279 (58%), Gaps = 15/279 (5%) Query: 10 LQGKVALVTGGSRGAGRGIALELAKAGAYVYITGRS-RGLSQEDRRKGTIDSVLDEIRAA 68 L G+VALV G +RGAGRGIA+EL AGA VY+TGRS R E R TI+ D + A Sbjct: 9 LAGRVALVAGATRGAGRGIAVELGAAGATVYVTGRSTRVRRSEYDRPETIEDTADLVTEA 68 Query: 69 GGEGEAVRCDHTRDSETEAVIGRISSEQGRLDILVNNVWGGNERSIASKPFWELPTDHWS 128 GG G AV DH + AV+ RI+SEQ RLDILVN++WGG P WE D Sbjct: 69 GGHGVAVPADHLDPDQVAAVVDRIASEQARLDILVNDIWGGETLFEWDSPVWEHDLDKGL 128 Query: 129 HMFDAGVRAQLMTNYYAVPLMRSNREGGGIIIHTT------YWDHYKYIDNFYYDLAKNA 182 + V +T+++A+PL+ R GG+++ T DHY+ ++F+YDLAK + Sbjct: 129 RLLRLAVETHAITSHHALPLLL--RRPGGLVVEVTDGTDAYNRDHYR--NSFFYDLAKTS 184 Query: 183 LVRMAFGLSVELAADKIAVIPLSPGWMRTELVLESLNTDEEHWQD----VAELQTSESTA 238 ++RMAF L E+ + L+PGW+R+E++L+ EE+W+D V SE+ Sbjct: 185 VLRMAFSLGHEVGPRGATAVALTPGWLRSEIMLDHFGVREENWRDALDRVPHFAISETPR 244 Query: 239 YIGRAVVRLAADPEVLAMTGIPQQVGSLAEKYGFTDVDG 277 Y+GRAV LAADP V G GSLA +YGFTD+DG Sbjct: 245 YVGRAVTALAADPGVARFNGRSFSSGSLAREYGFTDLDG 283 >gb|AAS69752.1| oxidoreductase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130] Length = 307 Score = 212 bits (540), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 119/281 (42%), Positives = 164/281 (58%), Gaps = 21/281 (7%) Query: 9 NLQGKVALVTGGSRGAGRGIALELAKAGAYVYITGRS-RGLSQEDRRKGTIDSVLDEIRA 67 NL+GKVALVTG +RGAGRGIAL L +AG VY+TGRS + + RK TI+ + I Sbjct: 5 NLEGKVALVTGATRGAGRGIALALGEAGVTVYVTGRSIKDKHPKINRKETIEETAERINK 64 Query: 68 AGGEGEAVRCDHTRDSETEAVIGRISSEQGRLDILVNNVWGGNERSIASKPFWELPTDHW 127 GG+ + DHT E +++ RI EQG+L+ILVN++WGG+ PF E W Sbjct: 65 LGGKAIWAQVDHTNPKEVKSLFERIDQEQGKLNILVNDIWGGD-------PFIEWSCKFW 117 Query: 128 SHMFDAGVRAQ-------LMTNYYAVPLMRSNREGGGIIIHTTYWDHYKYIDNFYYDLAK 180 H + G++ Q L+TNY+A PLM N G+I+ T Y+Y + YY L K Sbjct: 118 EHSLENGLKVQKNCLNSHLITNYFATPLMIRNH--SGLILEITDGTDYRYRGSVYYTLVK 175 Query: 181 NALVRMAFGLSVELAADKIAVIPLSPGWMRTELVLESLNTDEEHWQDV----AELQTSES 236 +++ +A LS EL + VI L+PG++R+E +L+ EE+W+D SE+ Sbjct: 176 CSIINLASSLSEELKPYGVTVISLTPGFLRSEAMLDYFGVLEENWKDAILKDPHFIASET 235 Query: 237 TAYIGRAVVRLAADPEVLAMTGIPQQVGSLAEKYGFTDVDG 277 TAYIGRAV+ LA DP V TG L+E+Y FTD+DG Sbjct: 236 TAYIGRAVISLAEDPNVFLKTGSATSTWRLSEEYNFTDLDG 276 >ref|ZP_00057549.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Thermobifida fusca] Length = 328 Score = 210 bits (534), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 122/279 (43%), Positives = 167/279 (59%), Gaps = 11/279 (3%) Query: 8 TNLQGKVALVTGGSRGAGRGIALELAKAGAYVYITGRSRGLS-QEDRRKGTIDSVLDEIR 66 + L GKVALV G +RGAGRGIA+EL AGA VY+TGR+ E R TI+ D + Sbjct: 27 SPLHGKVALVAGATRGAGRGIAVELGAAGATVYVTGRTTRTRRSEYNRPETIEDTADLVT 86 Query: 67 AAGGEGEAVRCDHTRDSETEAVIGRISSEQGRLDILVNNVWGGNERSIASKPFWELPTDH 126 AAGG G AV DH + +++ RISSEQGRLDILVN+VWGG P WE D+ Sbjct: 87 AAGGHGVAVPTDHLVPDQVRSLVERISSEQGRLDILVNDVWGGELLFEWDVPLWEHNLDN 146 Query: 127 WSHMFDAGVRAQLMTNYYAVPLMRSNREGGGIIIHTT----YWDHYKYIDNFYYDLAKNA 182 M GV +T++YA+PL+ R GG+++ T ++ Y ++F+YDL K A Sbjct: 147 GLRMLRLGVDTHAITSHYALPLLL--RRPGGLVVEVTDGTAEYNGSHYRNSFFYDLVKTA 204 Query: 183 LVRMAFGLSVELAADKIAVIPLSPGWMRTELVLESLNTDEEHWQDV----AELQTSESTA 238 ++RMAF LS E+ + ++PGW+R+EL+L++ EE+W+D SE+ Sbjct: 205 VLRMAFALSREIGPRGATAVAVTPGWLRSELMLDAYGVTEENWRDALAQEPHFCISETPR 264 Query: 239 YIGRAVVRLAADPEVLAMTGIPQQVGSLAEKYGFTDVDG 277 Y+GRA+ LAADP+V G G LA+ YGFTD+DG Sbjct: 265 YVGRAIAALAADPDVARWNGASLSSGQLAQVYGFTDLDG 303 >ref|NP_241276.1| BH0410~unknown conserved protein in others [Bacillus halodurans] pir||B83701 hypothetical protein BH0410 [imported] - Bacillus halodurans (strain C-125) dbj|BAB04129.1| BH0410~unknown conserved protein in others [Bacillus halodurans] Length = 302 Score = 207 bits (527), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 114/280 (40%), Positives = 164/280 (58%), Gaps = 12/280 (4%) Query: 7 MTNLQGKVALVTGGSRGAGRGIALELAKAGAYVYITGRS-RGLSQEDRRKGTIDSVLDEI 65 M L GKVALV G +RGAGRGIA+EL AGA VY+TGR+ R E R TI+ + + Sbjct: 1 MKPLIGKVALVAGATRGAGRGIAVELGAAGATVYVTGRTTRERRSEYNRPETIEETAELV 60 Query: 66 RAAGGEGEAVRCDHTRDSETEAVIGRISSEQGRLDILVNNVWGGNERSIASKPFWELPTD 125 AGG G AV DH + EA++ +I EQG+LD+LVN++WGG + + P W+ D Sbjct: 61 TNAGGTGIAVPVDHLDPQKVEALVSQIEREQGKLDVLVNDIWGGELLTEWNAPVWQHSLD 120 Query: 126 HWSHMFDAGVRAQLMTNYYAVPLMRSNREGGGIIIH----TTYWDHYKYIDNFYYDLAKN 181 M + L+T+++A+PL+ +R G+++ T ++ Y YYDLAK Sbjct: 121 DGLRMLRLAIDTHLITSHFALPLLLKSR---GLVVEMTDGTAEYNREHYRQPLYYDLAKT 177 Query: 182 ALVRMAFGLSVELAADKIAVIPLSPGWMRTELVLESLNTDEEHWQDVA----ELQTSEST 237 +++RMA+GL+ EL + + L+PGWMR+E++L+ E +W+D SES Sbjct: 178 SVLRMAWGLAQELQPHECTAVALTPGWMRSEIMLDHFEVTERNWRDATIKEPHFVISESP 237 Query: 238 AYIGRAVVRLAADPEVLAMTGIPQQVGSLAEKYGFTDVDG 277 ++GRAV LA+DP V G G LA+ YGFTD+DG Sbjct: 238 RFVGRAVAALASDPNVSRWNGQSLSSGQLAQAYGFTDLDG 277 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 416,187,097 Number of extensions: 16791333 Number of successful extensions: 61561 Number of sequences better than 1.0e-05: 2954 Number of HSP's gapped: 60518 Number of HSP's successfully gapped: 2960 Length of query: 287 Length of database: 757,237,578 Length adjustment: 124 Effective length of query: 163 Effective length of database: 420,565,302 Effective search space: 68552144226 Effective search space used: 68552144226 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 125 (52.8 bits)