BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0238.0001.p (920 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00037192.1| COG0383: Alpha-mannosidase [Enterococcus faec... 834 0.0 ref|NP_815413.1| glycosyl hydrolase, family 38 [Enterococcus fae... 812 0.0 ref|NP_269660.1| conserved hypothetical protein [Streptococcus p... 805 0.0 ref|NP_786825.1| alpha-mannosidase (putative) [Lactobacillus pla... 798 0.0 ref|NP_607667.1| conserved hypothetical protein [Streptococcus p... 793 0.0 >ref|ZP_00037192.1| COG0383: Alpha-mannosidase [Enterococcus faecium] Length = 900 Score = 834 bits (2154), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/868 (47%), Positives = 565/868 (65%), Gaps = 15/868 (1%) Query: 7 KKTAHIVSHTHWDREWYLPYEKHHVRLVQLVDALLDKLDSSTAFRSFYLDGQTIILEDYL 66 KK +I+SH+HWDREWY+ YE+HH+RL++L+D LL+ + +F SF+LDGQTIIL+DYL Sbjct: 2 KKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPSFNSFHLDGQTIILDDYL 61 Query: 67 QVRPENKQRLEQHIRAGRILIGPWYILQDAFLTSGEANVRNMQIGHQDALKYGEPSKIGY 126 QVRPE +Q ++Q I G++ IGP+YILQD FL S E+NVRNM IG +++ K+G P +GY Sbjct: 62 QVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRNMLIGMEESRKWGTPVMLGY 121 Query: 127 FPDTFGLVGQTPQLMLQSGIRNAFFGRGVKPTGFNNTVSDG-GYESSFSELIWEGPDGSR 185 FPDTFG +GQTPQLM Q+GI A FGRGVKP GF+N V + Y S +SE+ W+GPD + Sbjct: 122 FPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVLEAENYSSQYSEMWWKGPDQTA 181 Query: 186 ILGILFANWYSNGNEVPVDEAAAREFWDRKLADAEKYASTGELLFMNGCDHQPLQLDLPE 245 I G+LFANWYSNGNE+PV++ AA FW +KLADAE+YAST LL MNG DHQP+Q D+ + Sbjct: 182 IFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQYASTNHLLMMNGVDHQPVQKDISK 241 Query: 246 AIATAQALYPGVEFVHSNFPDYLDALNAELEKGGESGTLELSSVTGELRSQRTDGWGTLV 305 AI A L+P EF+HSNF DYL+A+ ++ + +L SV GEL SQ TDGW TL Sbjct: 242 AIHLANELFPDYEFIHSNFTDYLEAVQKDVPE-------DLGSVEGELTSQETDGWYTLA 294 Query: 306 NTASARVYLKQMNQKGQALLEKAAEPLASIAGLAGKDYPHHLFTYAWKTLMQNHPHDSIC 365 NTASARVYLKQ N K Q LE EPLA++A +YPH YAWKTLMQNHPHDSIC Sbjct: 295 NTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPHDQLDYAWKTLMQNHPHDSIC 354 Query: 366 GCSVDEVHREMVTRFDKSRHIAESIIEDSARFIAGAVDTSVFAGAAEAVPFVVMNTTGWS 425 GCSVD VHREM+ RF+K+ + + + +DS + A+DT+ F ++ PFV++NT G Sbjct: 355 GCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAIDTTGF--PKDSFPFVIVNTAGMD 412 Query: 426 RTGTVSIELDAARLYLREGYGLEETSRRMQEFDLSGRVLLDDSGKALACTVEDLGLEFGY 485 +TG I ++ R EG E+ + ++ + SG + + + ++FGY Sbjct: 413 KTGEAEITIELERKRFAEGIP-EQLYQELENLPKRKYHVETKSGATIPAILSEETVQFGY 471 Query: 486 DLPDDKFRQPFMCRRVKLTFEAAEVPALGLRXXXXXXXXXXXXXXXXSLVSGGHVLENAA 545 DLP D+FR P+M R +K+T +PA + G ++EN Sbjct: 472 DLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVEGEAKAEEKETMIHQSGRIIENGP 531 Query: 546 VRVEVAADGSFSLHHKQSGAVYRDLGIYENTGDIGNEYMYRQPDGELP-LTTKGLDAAVA 604 + + + +G+ ++ +++ +L I+E+ GDIGNEY+++QP + P L++ ++ V Sbjct: 532 LHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIGNEYIFKQPFCDQPILSSNKENSEVK 591 Query: 605 VLEDTPFRAAIEITHAWEIPASADARLNEEQRALVYYPERKAQRSTGTVILQLRTVISLE 664 VL DTP A I I EIP SAD RL +EQ+ +V + RKA+RS ILQ++T++++ Sbjct: 592 VLVDTPEIAKISILQEMEIPVSADERLEKEQQMVVEFRYRKAERSKEKRILQIKTIMTIR 651 Query: 665 REGKGLHIESTINNTAKDHRVRMLFPTDLQTAVHHADSMFEIAKRDNEPAAEWQNPSNTQ 724 ++ K + E+T++N KDHR+R+LFPT L H ADS+FE+ KR N + W+NP+N Q Sbjct: 652 KDSKKIDFETTLDNQMKDHRLRVLFPTKLHVEHHEADSIFEVVKRPNHVSKSWENPTNPQ 711 Query: 725 HQQSFVDVSTAEAGLTVANLGLNEYEVLRDGRNTIAVTLLRSVGELGDWGWFPTPEAQCL 784 HQQ+FV++ E G+TV N GLNEYEV DG+ IAVTLLRSVGELGDWG+FPTPEAQCL Sbjct: 712 HQQAFVNIHDEEYGVTVGNFGLNEYEVTEDGQ--IAVTLLRSVGELGDWGYFPTPEAQCL 769 Query: 785 GEHTVQLMLIPHTGDGITSGAYAQAYQFQAPWTTFQTDIHSGTITSGYSPLSWKGTEAAF 844 GEH + H G Y AY Q P++T Q H GT+ S L+ K A Sbjct: 770 GEHRFNYSIELH-GPEEKFSTYLHAYAAQIPFSTQQIKHHEGTLISKQQYLTIKSETFAI 828 Query: 845 SSMKMNATTGDLLLRWYNMSGSQAQLDV 872 +++K + + +++R +NMS +L++ Sbjct: 829 TALKRSKFSDKVVVRGFNMSSHLEKLEI 856 >ref|NP_815413.1| glycosyl hydrolase, family 38 [Enterococcus faecalis V583] gb|AAO81483.1| glycosyl hydrolase, family 38 [Enterococcus faecalis V583] Length = 896 Score = 812 bits (2097), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/891 (46%), Positives = 576/891 (64%), Gaps = 16/891 (1%) Query: 4 MTKKKTAHIVSHTHWDREWYLPYEKHHVRLVQLVDALLDKLDSSTAFRSFYLDGQTIILE 63 MTKKK +IVSH+HWDREWYLPYE+HH+RL++LVD +LD +++ F SF+LDGQTIIL+ Sbjct: 1 MTKKK-VYIVSHSHWDREWYLPYEEHHMRLIELVDNVLDLIENDPEFNSFHLDGQTIILD 59 Query: 64 DYLQVRPENKQRLEQHIRAGRILIGPWYILQDAFLTSGEANVRNMQIGHQDALKYGEPSK 123 DYLQVRPE K+ +++ ++AG++ IGP+YILQD FL S E+NVRNM IGH ++ K+G P + Sbjct: 60 DYLQVRPEKKEAVKKAVQAGKLKIGPFYILQDDFLISSESNVRNMLIGHLESQKWGAPVQ 119 Query: 124 IGYFPDTFGLVGQTPQLMLQSGIRNAFFGRGVKPTGFNNTVSDGGYESSFSELIWEGPDG 183 +GYFPDTFG +GQTPQ+M + + A FGRGVKP GF+N V + Y S +SE+ WEGPD Sbjct: 120 LGYFPDTFGNMGQTPQMMQLANLPAAAFGRGVKPIGFDNQVLESDYSSQYSEMWWEGPDQ 179 Query: 184 SRILGILFANWYSNGNEVPVDEAAAREFWDRKLADAEKYASTGELLFMNGCDHQPLQLDL 243 ++I G+LFANWYSNGNE+P ++ AA FW +KLAD E+YAST LL MNG DHQP+Q D+ Sbjct: 180 TKIFGLLFANWYSNGNEIPSEKEAAIAFWKQKLADVERYASTNHLLMMNGVDHQPVQRDI 239 Query: 244 PEAIATAQALYPGVEFVHSNFPDYLDALNAELEKGGESGTLELSSVTGELRSQRTDGWGT 303 +AIA A L+P EF+HSNF DYL A+ EL + +L +VTGEL SQ TDGW T Sbjct: 240 TKAIALANELFPEYEFIHSNFDDYLKAVQEELPE-------DLGTVTGELTSQETDGWYT 292 Query: 304 LVNTASARVYLKQMNQKGQALLEKAAEPLASIAGLAGKDYPHHLFTYAWKTLMQNHPHDS 363 L NT+SARVYLKQ N K Q LE AEPLA++A DYPH F YAWKTL+QNHPHDS Sbjct: 293 LANTSSARVYLKQWNTKVQRQLENIAEPLAAMAYEVTGDYPHDQFDYAWKTLLQNHPHDS 352 Query: 364 ICGCSVDEVHREMVTRFDKSRHIAESIIEDSARFIAGAVDTSVFAGAAEAVPFVVMNTTG 423 ICGCSVDEVHR M+TRF+ + + + +++ R + A+DTSVF A PFV+ NT+G Sbjct: 353 ICGCSVDEVHRGMMTRFENANDVGHFLADEATRQLTEAIDTSVFPEKAH--PFVLFNTSG 410 Query: 424 WSRTGTVSIELDAARLYLREGYGLEETSRRMQEFDLSGRVLLDDSGKALACTVEDLGLEF 483 + +T V++E++ RL G E+ +++ ++D +GKA+A + + F Sbjct: 411 YQKTEVVTVEVEIERLPFYTG-KPEDLYHELKQKATPDYQVIDPTGKAVASRIVKEDVRF 469 Query: 484 GYDLPDDKFRQPFMCRRVKLTFEAAEVPALGLRXXXXXXXXXXXXXXXXSLVSGGHVLEN 543 GYDLP D FRQP+M + + + E+ + +EN Sbjct: 470 GYDLPKDAFRQPYMAKYLTVELSVKEMAPFSWDSFALIQGETKAFEGSLLAQPATNEMEN 529 Query: 544 AAVRVEVAADGSFSLHHKQSGAVYRDLGIYENTGDIGNEYMYRQPDGELPLTTKGLDAAV 603 ++V++ +GS ++ K++G + L +E+TGDIGNEY++ +P + +TT+ + A + Sbjct: 530 EFIQVKIENNGSLTIADKKTGETFSKLLTFEDTGDIGNEYIFFKPTEDQGITTENVTAEI 589 Query: 604 AVLEDTPFRAAIEITHAWEIPASADARLNEEQRALVYYPERKAQRSTGTVILQLRTVISL 663 E++P +A+ +I +P +AD RL EEQ+A+ + ER AQRST ++ T++++ Sbjct: 590 TNKENSPVKASYQIKQTVMLPVAADERLEEEQKAVREFRERLAQRSTTLRPFEITTMVTM 649 Query: 664 EREGKGLHIESTINNTAKDHRVRMLFPTDLQTAVHHADSMFEIAKRDNEPAAEWQNPSNT 723 +E L E+TINN KDHR+R+LFPT + T H ADS++E+ R N+ + W+NP+N Sbjct: 650 IKESNQLFFETTINNQIKDHRLRVLFPTGMVTETHEADSIYEVVTRPNQVSDTWENPTNP 709 Query: 724 QHQQSFVDVSTAEAGLTVANLGLNEYEVLRDGRNTIAVTLLRSVGELGDWGWFPTPEAQC 783 QHQQ+FV+V G+T+ N GLNEYEVL DG TIAVTL+R VGELGDWG+F TPEAQC Sbjct: 710 QHQQAFVNVHDQNKGVTIFNEGLNEYEVLADG--TIAVTLIRCVGELGDWGYFATPEAQC 767 Query: 784 LGEHTVQLMLIPHTGDGITSGAYAQAYQFQAPWTTFQTDIHSGTITSGYSPLSWKGTEAA 843 GE+T + L H Y QAY Q P+T T H G + + L+ Sbjct: 768 QGEYTFKYGLSLHGKPEERFATYQQAYSAQIPFTAATTARHEGKLAPNHVYLTTAEGPIG 827 Query: 844 FSSMKMNATTGDLLLRWYNMSGSQAQLDV-QLGLPHEHLYRTGILEESTAP 893 ++++K T L++R +N++ ++ + P L T +LEE P Sbjct: 828 WTAVKRQEQTNHLVVRGFNLTAQNIPCELHKETQPATCL--TNVLEEPLTP 876 >ref|NP_269660.1| conserved hypothetical protein [Streptococcus pyogenes] gb|AAK34381.1| conserved hypothetical protein [Streptococcus pyogenes M1 GAS] Length = 901 Score = 805 bits (2078), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/919 (46%), Positives = 572/919 (62%), Gaps = 36/919 (3%) Query: 8 KTAHIVSHTHWDREWYLPYEKHHVRLVQLVDALLDKLDSSTAFRSFYLDGQTIILEDYLQ 67 K HI+SH+HWDREWY+ YE+HH+RL+ L+D LL+ + F SF+LDGQTIIL+DYL+ Sbjct: 4 KKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDDYLK 63 Query: 68 VRPENKQRLEQHIRAGRILIGPWYILQDAFLTSGEANVRNMQIGHQDALKYGEPSKIGYF 127 VRPE + + Q I +G++ IGP+YILQD FLTS E+NVRNM IG +D ++G +GYF Sbjct: 64 VRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPLGYF 123 Query: 128 PDTFGLVGQTPQLMLQSGIRNAFFGRGVKPTGFNNTV-SDGGYESSFSELIWEGPDGSRI 186 PDTFG +GQTPQLML++G++ A FGRG++PTGFNN V + Y S FSE+ W+GPD SRI Sbjct: 124 PDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQVDTSEKYSSQFSEISWQGPDNSRI 183 Query: 187 LGILFANWYSNGNEVPVDEAAAREFWDRKLADAEKYASTGELLFMNGCDHQPLQLDLPEA 246 LG+LFANWYSNGNE+P EA AR FWD+KLADAE++AST LL MNGCDHQP+QLD+ +A Sbjct: 184 LGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDVTKA 243 Query: 247 IATAQALYPGVEFVHSNFPDYLDALNAELEKGGESGTLELSSVTGELRSQRTDGWGTLVN 306 IA A LYP EFVHS F DYL L +L + LS+V GE+ SQ TDGW TL N Sbjct: 244 IALANQLYPDYEFVHSCFEDYLADLADDLPEN-------LSTVQGEITSQETDGWYTLAN 296 Query: 307 TASARVYLKQMNQKGQALLEKAAEPLASIAGLAGKDYPHHLFTYAWKTLMQNHPHDSICG 366 TASAR+YLKQ N + LE EPLA++A YPH YAWKTLMQNHPHDSICG Sbjct: 297 TASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYPHDQLRYAWKTLMQNHPHDSICG 356 Query: 367 CSVDEVHREMVTRFDKSRHIAESIIEDSARFIAGAVDTSVFAGAAEAVPFVVMNTTGWSR 426 CSVD VHREM+TRF+K+ + + +++A+ IA A+DT F ++ PFV+ NT+G S+ Sbjct: 357 CSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAIDTRDF--PMDSQPFVLFNTSGHSK 414 Query: 427 TGTVSIELDAARLYLREGYGLEETSRRMQEF--DLSGRVLLDDSGKALACTVEDLG--LE 482 T + L + + + + +E + QE+ LS + D+ + E LG + Sbjct: 415 TSVAELSLTWKKYHFGQRFP-KEVYQEAQEYLARLSQSFQIIDTSGQVRPEAEILGTSIA 473 Query: 483 FGYDLPDDKFRQPFMCRRVKLTFEAAEVPALGLRXXXXXXXXXXXXXXXXSLV-SGGHVL 541 F YDLP FR+P+ +V+L +PA+ + SL L Sbjct: 474 FDYDLPKRSFREPYFAIKVRLRLPIT-LPAMSWKTLALKLGNETTPSETVSLYDDSNQCL 532 Query: 542 ENAAVRVEVAADGSFSLHHKQSGAVYRDLGIYENTGDIGNEYMYRQPDGELPLTTKGLDA 601 EN ++V + DG ++ KQSG +Y+DL +E+ GDIGNEY+ RQP+ + P Sbjct: 533 ENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFEDCGDIGNEYISRQPNHDQPFYADQGTI 592 Query: 602 AVAVLEDTPFRAAIEITHAWEIPASADARLNEEQRALVYYPERKAQRSTGTVILQLRTVI 661 + ++ +T A +EI + IP SAD L E A++ ER+A+RS L L T+I Sbjct: 593 KLNIISNTAQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRSQEKAELTLTTLI 652 Query: 662 SLEREGKGLHIESTINNTAKDHRVRMLFPTDLQTAVHHADSMFEIAKRDNEPAAE-WQNP 720 +E+ L + +N +HR+R+LFPT L+T H ADS+FE KR N P A W+NP Sbjct: 653 RMEKNNPRLQFTTRFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNP 712 Query: 721 SNTQHQQSFVDVSTAEAGLTVANLGLNEYEVLRDGRNTIAVTLLRSVGELGDWGWFPTPE 780 SN QHQ+ FV + E G+T+ N GLNEYE+L D NTIA+TLLRSVGE+GDWG+FPTPE Sbjct: 713 SNPQHQECFVSLFDGENGVTIGNYGLNEYEILPDT-NTIAITLLRSVGEMGDWGYFPTPE 771 Query: 781 AQCLGEHTVQLMLIPHTGDGITS----GAYAQAYQFQAPWTTFQTDIHSGTITSGYSPLS 836 AQCLG+H+ + ++ + IT +Y +A + Q P T QT+ H GT+ + YS L+ Sbjct: 772 AQCLGKHS-----LSYSFESITKQTQFASYWRAQEGQVPVITTQTNQHEGTLAAEYSYLT 826 Query: 837 WKGTEAAFSSMKMNATTGDLLLRWYNMSGSQAQLDVQLGLPHEHLYRTGILEESTAPLPD 896 + A ++ K L+ R YN+S + D L LP+ + T +LE+ + Sbjct: 827 GTNDQVALTAFKRRLADNALITRSYNLSNDKT-CDFSLSLPNYNAKVTNLLEKDSKQSTP 885 Query: 897 SGDARHLLELGPCEIATFG 915 S +LG EI T Sbjct: 886 S-------QLGKAEILTLA 897 >ref|NP_786825.1| alpha-mannosidase (putative) [Lactobacillus plantarum WCFS1] emb|CAD65703.1| alpha-mannosidase (putative) [Lactobacillus plantarum WCFS1] Length = 899 Score = 798 bits (2060), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/876 (46%), Positives = 553/876 (63%), Gaps = 16/876 (1%) Query: 4 MTKKKTAHIVSHTHWDREWYLPYEKHHVRLVQLVDALLDKLDSSTAFRSFYLDGQTIILE 63 MTKKK ++SH+HWDREWY+P+E+HH+RLV L+D LLD + + F SF+LDGQ I L+ Sbjct: 1 MTKKK-VFVISHSHWDREWYMPFEQHHMRLVTLIDNLLDVFKNDSDFDSFHLDGQMIALD 59 Query: 64 DYLQVRPENKQRLEQHIRAGRILIGPWYILQDAFLTSGEANVRNMQIGHQDALKYGEPSK 123 DYL VRPE K L I+AG++ IGP+YILQD FL S E+NVRNM IG A +YG+ Sbjct: 60 DYLAVRPERKPELAAAIKAGKLRIGPFYILQDDFLISPESNVRNMIIGRDQAREYGQEVP 119 Query: 124 IGYFPDTFGLVGQTPQLMLQSGIRNAFFGRGVKPTGFNNTVSDGGYESSFSELIWEGPDG 183 +GYFPDTFG +GQTPQ+M + ++ A FGRGV PTGFNN V D Y S +SE+ W+GPDG Sbjct: 120 LGYFPDTFGNMGQTPQMMTLANLKTAAFGRGVTPTGFNNQVGDADYASQYSEMWWQGPDG 179 Query: 184 SRILGILFANWYSNGNEVPVDEAAAREFWDRKLADAEKYASTGELLFMNGCDHQPLQLDL 243 +RILG+LFANWYSNGNE+PV+ AA++FWD+KLADAEK+AST LL MNG DHQP+QLD+ Sbjct: 180 TRILGLLFANWYSNGNEIPVERTAAKKFWDQKLADAEKFASTDNLLMMNGVDHQPVQLDV 239 Query: 244 PEAIATAQALYPGVEFVHSNFPDYLDALNAELEKGGESGTLELSSVTGELRSQRTDGWGT 303 AI A LYP EF+HSNF DYL L+A+L K +LS++ GEL SQ TDGW T Sbjct: 240 TAAIKVANELYPDYEFIHSNFTDYLATLSADLPK-------DLSTIHGELTSQETDGWYT 292 Query: 304 LVNTASARVYLKQMNQKGQALLEKAAEPLASIAGLAGKDYPHHLFTYAWKTLMQNHPHDS 363 L NTAS+RVYLKQ N K + LLE AEPLA++A A DYPH YAWK L+QNHPHDS Sbjct: 293 LANTASSRVYLKQENTKNERLLENQAEPLAAMAYPAA-DYPHDRLRYAWKLLLQNHPHDS 351 Query: 364 ICGCSVDEVHREMVTRFDKSRHIAESIIEDSARFIAGAVDTSVFAGAAEAVPFVVMNTTG 423 ICGCSVDEVHREM+TRF KS+ +A + D+ + ++T+ F +A PFVV+NTTG Sbjct: 352 ICGCSVDEVHREMLTRFAKSQEVARFVAHDALTTLTAKINTTDF--NEQAKPFVVVNTTG 409 Query: 424 WSRTGTVSIELDAARLYLREGYGLEETSRRMQE--FDLSGRVLLDDSGKALACTVEDLGL 481 +++TG I ++ R+ ++E ++++ +L +++D G+++ + D + Sbjct: 410 FTKTGLTRIVVEWDRIAFSATGTIQEQRHQLEQRLAELPELMVVDAHGQSVPFRLIDQQV 469 Query: 482 EFGYDLPDDKFRQPFMCRRVKLTFEAAEVPALGLRXXXXXXXXXXXXXXXXSLVSGGHVL 541 F YDLP D+FR PF + + +PA R + + ++ Sbjct: 470 AFHYDLPKDRFRDPFQAIELTIELNVVNMPAFAWRTLALQPATQTLVPNAM-VKAQPRLI 528 Query: 542 ENAAVRVEVAADGSFSLHHKQSGAVYRDLGIYENTGDIGNEYMYRQPDGELPLTTKGLDA 601 N +++ V DGS ++ ++++ Y + ++E+TGD+GNEY+YRQ + + Sbjct: 529 SNEWLKIGVEDDGSLTITNRETNKTYHQMLVFEDTGDMGNEYIYRQTADKRAYYSTDFPM 588 Query: 602 AVAVLEDTPFRAAIEITHAWEIPASADARLNEEQRALVYYPERKAQRSTGTVILQLRTVI 661 V V+ + +E+ + E+P SAD +L +E A+V +R AQRST V L + T I Sbjct: 589 EVRVVHADELGSELELINYLEVPTSADEQLAKETHAIVDITQRTAQRSTQKVPLTITTKI 648 Query: 662 SLEREGKGLHIESTINNTAKDHRVRMLFPTDLQTAVHHADSMFEIAKRDNEPAAEWQNPS 721 L + + ES +NN AKDHR+R+LF T L H ADS++E R N PA WQNP+ Sbjct: 649 RLNPNSRQIQFESHVNNQAKDHRLRVLFKTALTAETHVADSIYETVTRANRPAKNWQNPT 708 Query: 722 NTQHQQSFVDVSTAEAGLTVANLGLNEYEVLRDGRNTIAVTLLRSVGELGDWGWFPTPEA 781 N QHQQ+F V G+TV NLGLNEYE+L NTIA+T+LR VGE+GDWG+F TPEA Sbjct: 709 NPQHQQAFACVFNEANGVTVGNLGLNEYEIL-PADNTIALTMLRCVGEMGDWGYFATPEA 767 Query: 782 QCLGEHTVQLML-IPHTGDGITSGAYAQAYQFQAPWTTFQTDIHSGTITSGYSPLSWKGT 840 QC G T L + + +Y +A Q P++ QT H+GT+ + L+ Sbjct: 768 QCQGAFTFNYSLELTDGSEAQRIASYQRAQGMQTPFSNQQTWQHTGTLEADDQYLTLATP 827 Query: 841 EAAFSSMKMNATTGDLLLRWYNMSGSQAQLDVQLGL 876 E A +S+K + L +R YN+S Q L V L Sbjct: 828 EFAVTSLKRANNSAGLTVRGYNLSDRQVPLKVTTSL 863 >ref|NP_607667.1| conserved hypothetical protein [Streptococcus pyogenes MGAS8232] gb|AAL98166.1| conserved hypothetical protein [Streptococcus pyogenes MGAS8232] Length = 901 Score = 793 bits (2048), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/916 (45%), Positives = 569/916 (62%), Gaps = 30/916 (3%) Query: 8 KTAHIVSHTHWDREWYLPYEKHHVRLVQLVDALLDKLDSSTAFRSFYLDGQTIILEDYLQ 67 K HI+SH+HWDREWY+ YE+HH+RL+ L+D LL+ + F SF+LDGQTIIL+DYL+ Sbjct: 4 KKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDDYLK 63 Query: 68 VRPENKQRLEQHIRAGRILIGPWYILQDAFLTSGEANVRNMQIGHQDALKYGEPSKIGYF 127 VRPE + + Q I +G++ IGP+YILQD FLTS E+NVRNM IG +D ++G +GYF Sbjct: 64 VRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPLGYF 123 Query: 128 PDTFGLVGQTPQLMLQSGIRNAFFGRGVKPTGFNNTV-SDGGYESSFSELIWEGPDGSRI 186 PDTFG +GQTPQLML++G++ A FGRG++PTGFNN V + Y S FSE+ W+GPD S I Sbjct: 124 PDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQVDTSEKYSSQFSEISWQGPDDSHI 183 Query: 187 LGILFANWYSNGNEVPVDEAAAREFWDRKLADAEKYASTGELLFMNGCDHQPLQLDLPEA 246 LG+LFANWYSNGNE+P EA AR FWD+KLADAE++AST LL MNGCDHQP+QLD+ +A Sbjct: 184 LGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDVTKA 243 Query: 247 IATAQALYPGVEFVHSNFPDYLDALNAELEKGGESGTLELSSVTGELRSQRTDGWGTLVN 306 IA A LYP EFVHS F DYL L +L + LS+V GE+ SQ TDGW TL N Sbjct: 244 IALANQLYPDYEFVHSCFEDYLADLADDLPEN-------LSTVQGEITSQETDGWYTLAN 296 Query: 307 TASARVYLKQMNQKGQALLEKAAEPLASIAGLAGKDYPHHLFTYAWKTLMQNHPHDSICG 366 TASAR+YLKQ N + LE EPLA++A YPH YAWKTLMQNHPHDSICG Sbjct: 297 TASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYPHDQLRYAWKTLMQNHPHDSICG 356 Query: 367 CSVDEVHREMVTRFDKSRHIAESIIEDSARFIAGAVDTSVFAGAAEAVPFVVMNTTGWSR 426 CSVD VHREM+TRF+K+ + + +++A+ IA A+DT F ++ PFV+ NT+G S+ Sbjct: 357 CSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAIDTRDFPMNSQ--PFVLFNTSGHSK 414 Query: 427 TGTVSIELDAARLYLREGYGLEETSRRMQEF--DLSGRVLLDDSGKALACTVEDLG--LE 482 T + L + + + + +E + QE+ LS + D+ ++ E LG + Sbjct: 415 TSVAELSLTWKKYHFGQRFP-KEVYQETQEYLAGLSQSFQIIDTSGQVSPEAEILGTSIA 473 Query: 483 FGYDLPDDKFRQPFMCRRVKLTFEAAEVPALGLRXXXXXXXXXXXXXXXXSLV-SGGHVL 541 F YDLP FR+P+ +V+L +PA+ + SL L Sbjct: 474 FDYDLPKRSFREPYFAIKVRLRLPIT-LPAMSWKTLALKLGNETTPSETDSLYDDSNQCL 532 Query: 542 ENAAVRVEVAADGSFSLHHKQSGAVYRDLGIYENTGDIGNEYMYRQPDGELPLTTKGLDA 601 EN ++V + DG ++ KQSG +Y+DL +E+ GDIGNEY+ RQP+ + P Sbjct: 533 ENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFEDCGDIGNEYISRQPNHDQPFYADQGTT 592 Query: 602 AVAVLEDTPFRAAIEITHAWEIPASADARLNEEQRALVYYPERKAQRSTGTVILQLRTVI 661 + ++ +T A +EI + IP SAD L E A++ ER++ RS L L T+I Sbjct: 593 KLNIISNTAQVAELEIQQTFAIPVSADKLLQAEMEAVIDITERQSGRSQEKAELTLTTLI 652 Query: 662 SLEREGKGLHIESTINNTAKDHRVRMLFPTDLQTAVHHADSMFEIAKRDNEP-AAEWQNP 720 +E+ L + +N +HR+R+LFPT L+T H ADS+FE KR N P AA W+NP Sbjct: 653 RMEKNNPRLQFTTRFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPNAAFWKNP 712 Query: 721 SNTQHQQSFVDVSTAEAGLTVANLGLNEYEVLRDGRNTIAVTLLRSVGELGDWGWFPTPE 780 SN QHQ+ FV + E G+T+ N GLNEYE+L D NTIA+TLLRSVGE+GDWG+FPTPE Sbjct: 713 SNPQHQECFVSLFDGEKGVTIGNYGLNEYEILPDS-NTIAITLLRSVGEMGDWGYFPTPE 771 Query: 781 AQCLGEHTVQLMLIPHTGDGITS-GAYAQAYQFQAPWTTFQTDIHSGTITSGYSPLSWKG 839 AQCLG+H++ + D T +Y +A + Q P QT H+G++ + +S ++ Sbjct: 772 AQCLGQHSLSYSF--ESIDRQTQFASYWRAQEGQVPILVEQTSHHTGSLRAEHSYVTGAD 829 Query: 840 TEAAFSSMKMNATTGDLLLRWYNMSGSQAQLDVQLGLPHEHLYRTGILEESTAPLPDSGD 899 + A ++ K L+ R YN+S + D L LP+ + T +LE+ + S Sbjct: 830 DQVALTAFKRRLADNALITRSYNLSNDKT-CDFSLSLPNYNAKVTNLLEKDSKQSTPS-- 886 Query: 900 ARHLLELGPCEIATFG 915 +LG EI T Sbjct: 887 -----QLGKAEILTLA 897 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.134 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 1,349,844,102 Number of extensions: 57385290 Number of successful extensions: 123618 Number of sequences better than 1.0e-05: 47 Number of HSP's gapped: 123490 Number of HSP's successfully gapped: 57 Length of query: 920 Length of database: 757,237,578 Length adjustment: 135 Effective length of query: 785 Effective length of database: 390,699,213 Effective search space: 306698882205 Effective search space used: 306698882205 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)