BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0235.0002.p (173 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value sp|O30408|TYCB_BREPA Tyrocidine synthetase II [Includes: ATP-dep... 69 5e-11 sp|O30409|TYCC_BREPA Tyrocidine synthetase III [Includes: ATP-de... 68 9e-11 dbj|BAA36755.1| bacitracin synthetase 2 (BA2) [Bacillus lichenif... 67 1e-10 sp|O68008|BACC_BACLI Bacitracin synthetase 3 (BA3) [Includes: AT... 64 2e-09 sp|O68007|BACB_BACLI Bacitracin synthetase 2 (BA2) [Includes: AT... 64 2e-09 >sp|O30408|TYCB_BREPA Tyrocidine synthetase II [Includes: ATP-dependent proline adenylase (ProA) (Proline activase); ATP-dependent phenylalanine adenylase (PheA) (Phenylalanine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); Phenylalanine racemase [ATP-hydrolyzing] ] pir||T31075 tyrocidine synthetase 2 - Brevibacillus brevis gb|AAC45929.1| tyrocidine synthetase 2 [Brevibacillus brevis] Length = 3587 Score = 68.9 bits (167), Expect = 5e-11, Method: Composition-based stats. Identities = 33/85 (38%), Positives = 48/85 (56%) Query: 30 EYWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETAL 89 +YW + LN+P+DY RPA +SF GE + RT +L L+ +A++ + L Sbjct: 1240 KYWLDRFAGEIPVLNLPMDYPRPAVQSFEGERYLFRTEKQLLESLQDVAQKTGTTLYMVL 1299 Query: 90 LACYILLLSKYTGQDTVCVXXXRMG 114 LA Y +LLSKY+GQD V + G Sbjct: 1300 LAAYHVLLSKYSGQDDVMIGTVTAG 1324 Score = 59.7 bits (143), Expect = 3e-08, Method: Composition-based stats. Identities = 31/78 (39%), Positives = 41/78 (52%) Query: 31 YWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETALL 90 YW + A+++P D+ RPA +SFAG V L EL L LA + LL Sbjct: 2276 YWLSTFAGNITAVDVPTDFPRPAVKSFAGGQVTLSMDQELLSALHELAAHTNTTLFMVLL 2335 Query: 91 ACYILLLSKYTGQDTVCV 108 A Y +LL+KY GQD + V Sbjct: 2336 AAYNVLLAKYAGQDDIIV 2353 >sp|O30409|TYCC_BREPA Tyrocidine synthetase III [Includes: ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); ATP-dependent glutamine adenylase (GlnA) (Glutamine activase); ATP-dependent tyrosine adenylase (TyrA) (Tyrosine activase); ATP-dependent valine adenylase (ValA) (Valine activase); ATP-dependent ornithine adenylase (OrnA) (Ornithine activase); ATP-dependent leucine adenylase (LeuA) (Leucine activase)] pir||T31076 tyrocidine synthetase 3 - Brevibacillus brevis gb|AAC45930.1| tyrocidine synthetase 3 [Brevibacillus brevis] Length = 6486 Score = 67.8 bits (164), Expect = 9e-11, Method: Composition-based stats. Identities = 32/79 (40%), Positives = 48/79 (60%) Query: 30 EYWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETAL 89 ++W N + LN+P DY RP+ +SFAG++V+ EL RL+++A + L Sbjct: 1233 QHWLNTFADEIPLLNLPTDYPRPSVQSFAGDLVLFAAGKELLERLQQVASETGTTLYMIL 1292 Query: 90 LACYILLLSKYTGQDTVCV 108 LA Y +LLSKYTGQ+ + V Sbjct: 1293 LAAYNVLLSKYTGQEDIIV 1311 Score = 58.9 bits (141), Expect = 5e-08, Method: Composition-based stats. Identities = 30/84 (35%), Positives = 44/84 (52%) Query: 31 YWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETALL 90 YW N LN+P DY RP+ +SFAG+ + + L +L +LA+ + LL Sbjct: 2271 YWLNTFTGEIPVLNLPTDYPRPSVKSFAGDRFVFGSGTALPKQLHQLAQETGTTLYMVLL 2330 Query: 91 ACYILLLSKYTGQDTVCVXXXRMG 114 A Y +LLSKY+ Q+ + V G Sbjct: 2331 AAYNVLLSKYSRQEDIIVGAPTAG 2354 Score = 58.5 bits (140), Expect = 6e-08, Method: Composition-based stats. Identities = 30/79 (37%), Positives = 42/79 (53%) Query: 30 EYWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETAL 89 ++W LN+P DY RP+ +SF G+ V L T L +L +LA + L Sbjct: 4343 DFWTRTFAGEIPLLNLPHDYPRPSVQSFDGDTVALGTGHHLLEQLRKLAAETGTTLFMVL 4402 Query: 90 LACYILLLSKYTGQDTVCV 108 LA Y +LLSKY GQ+ + V Sbjct: 4403 LAAYHVLLSKYAGQEEIVV 4421 Score = 57.0 bits (136), Expect = 2e-07, Method: Composition-based stats. Identities = 28/78 (35%), Positives = 41/78 (52%) Query: 31 YWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETALL 90 YW N LN+P D+ RP +SF G+ V + L L +LA+ + LL Sbjct: 3309 YWLNAFSGDIPVLNLPADFSRPLTQSFEGDCVSFQADKALLDDLHKLAQESQSTLFMVLL 3368 Query: 91 ACYILLLSKYTGQDTVCV 108 A Y +LL+KY+GQ+ + V Sbjct: 3369 AAYNVLLAKYSGQEDIVV 3386 Score = 56.2 bits (134), Expect = 3e-07, Method: Composition-based stats. Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 10/117 (8%) Query: 31 YWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETALL 90 YW + LN+P D+ RP+ +SFAG+ + L L +LA+ + LL Sbjct: 5388 YWLQTFADDIPVLNLPTDFTRPSTQSFAGDQCTIGAGKALTEGLHQLAQATGTTLYMVLL 5447 Query: 91 ACYILLLSKYTGQDTVCVXXXRMGLRSGSAVR---------LGRGRRPQRSGGTSEL 138 A Y +LL+KY GQ+ + V G RS + + L +PQR SE Sbjct: 5448 AAYNVLLAKYAGQEDIIVGTPITG-RSHADLEPIVGMFVNTLAMRNKPQREKTFSEF 5503 >dbj|BAA36755.1| bacitracin synthetase 2 (BA2) [Bacillus licheniformis] Length = 414 Score = 67.0 bits (162), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 31/78 (39%), Positives = 43/78 (55%) Query: 31 YWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETALL 90 YW N LNMPLD+ RP RSF G ++ + +L+ +A + V+ LL Sbjct: 254 YWLNTFRGDIPVLNMPLDFPRPKIRSFQGNRTVVELDQDTTKKLKTIAAKNGVTMYMLLL 313 Query: 91 ACYILLLSKYTGQDTVCV 108 A Y +LLSKYTGQ+ + V Sbjct: 314 AGYTILLSKYTGQEDIIV 331 >sp|O68008|BACC_BACLI Bacitracin synthetase 3 (BA3) [Includes: ATP-dependent isoleucine adenylase (IleA) (Isoleucine activase); ATP-dependent D-phenylalanine adenylase (D-PheA) (D-phenylalanine activase); ATP-dependent histidine adenylase (HisA) (Histidine activase); ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate activase); ATP-dependent asparagine adenylase (AsnA) (Asparagine activase); Aspartate racemase ; Phenylalanine racemase [ATP hydrolyzing] ] pir||T31679 bacitracin synthetase 3 - Bacillus licheniformis gb|AAC06348.1| bacitracin synthetase 3; BacC [Bacillus licheniformis] Length = 6359 Score = 63.5 bits (153), Expect = 2e-09, Method: Composition-based stats. Identities = 30/79 (37%), Positives = 42/79 (53%) Query: 30 EYWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETAL 89 +YW N+ LN+P D RP RS G++V GE + L +LA+ + L Sbjct: 3765 DYWLNVFQGEVPVLNLPADEKRPQKRSIEGDIVQFEIDGETSAMLNKLAKENGATMYMLL 3824 Query: 90 LACYILLLSKYTGQDTVCV 108 LA Y LL+KYTGQ+ + V Sbjct: 3825 LAGYTTLLAKYTGQEDIVV 3843 Score = 62.8 bits (151), Expect = 3e-09, Method: Composition-based stats. Identities = 30/79 (37%), Positives = 42/79 (53%) Query: 30 EYWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETAL 89 EYW N+ LNMP DY RP S G+ + GEL +L+R+A+ + L Sbjct: 1229 EYWLNIFKGEIPVLNMPTDYPRPQMHSVEGDRIGFAIDGELTKKLKRIAKDNGATMYMLL 1288 Query: 90 LACYILLLSKYTGQDTVCV 108 LA Y +LL Y+GQ+ V + Sbjct: 1289 LAAYTVLLRTYSGQEDVII 1307 >sp|O68007|BACB_BACLI Bacitracin synthetase 2 (BA2) [Includes: ATP-dependent lysine adenylase (LysA) (Lysine activase); ATP-dependent D-ornithine adenylase (D-OrnA) (D-ornithine activase); Ornithine racemase ] pir||T31678 bacitracin synthetase 2 bacB [imported] - Bacillus licheniformis gb|AAC06347.1| bacitracin synthetase 2; BacB [Bacillus licheniformis] Length = 2607 Score = 63.5 bits (153), Expect = 2e-09, Method: Composition-based stats. Identities = 31/78 (39%), Positives = 43/78 (55%) Query: 31 YWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETALL 90 YW N LNMPLD+ RP RSF G ++ + +L+ +A + V+ LL Sbjct: 254 YWLNTFRGDIPVLNMPLDFPRPKIRSFQGNRTVVELDQDTTKKLKTIAAKNGVTMYMLLL 313 Query: 91 ACYILLLSKYTGQDTVCV 108 A Y +LLSKYTGQ+ + V Sbjct: 314 AGYTILLSKYTGQEDIIV 331 Score = 62.0 bits (149), Expect = 5e-09, Method: Composition-based stats. Identities = 30/79 (37%), Positives = 45/79 (56%) Query: 30 EYWHNLIGNGTHALNMPLDYVRPAARSFAGEVVMLRTSGELACRLERLAEREAVSAETAL 89 E W ++ N LNMP D+ RP +S+ G+ + EL +L++ A+ V+ L Sbjct: 1284 ESWLSVFQNDIPVLNMPTDFPRPQMQSYEGDRIAFAIERELTDKLKKTAKENGVTMYMLL 1343 Query: 90 LACYILLLSKYTGQDTVCV 108 LA Y +LLSKYTGQ+ + V Sbjct: 1344 LAGYTILLSKYTGQEDIIV 1362 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.316 0.133 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 255,662,081 Number of extensions: 9916036 Number of successful extensions: 17600 Number of sequences better than 1.0e-05: 66 Number of HSP's gapped: 17603 Number of HSP's successfully gapped: 91 Length of query: 173 Length of database: 757,237,578 Length adjustment: 117 Effective length of query: 56 Effective length of database: 439,570,995 Effective search space: 24615975720 Effective search space used: 24615975720 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 121 (51.2 bits)