BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0016.p (484 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_622367.1| conserved hypothetical protein [Thermoanaerobac... 236 1e-60 ref|NP_393759.1| conserved hypothetical protein [Thermoplasma ac... 224 3e-57 ref|NP_069696.1| conserved hypothetical protein [Archaeoglobus f... 218 3e-55 ref|NP_229158.1| conserved hypothetical protein [Thermotoga mari... 215 2e-54 ref|ZP_00001116.1| COG1690: Uncharacterized conserved protein [F... 206 8e-52 >ref|NP_622367.1| conserved hypothetical protein [Thermoanaerobacter tengcongensis] gb|AAM23971.1| conserved hypothetical protein [Thermoanaerobacter tengcongensis] Length = 480 Score = 236 bits (601), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 164/466 (35%), Positives = 230/466 (49%), Gaps = 26/466 (5%) Query: 26 DLKVYASEQLFATL-DYKVLEMANNNLQIPNI-EYMSYTPDVHVGVGTCIGTTAVWDAAD 83 D VY ++ L L D + L N +P + E + PD+H G G IG + Sbjct: 30 DAVVYVNDSLKELLRDDQSLRQLVNAASLPGVVEPVIGMPDIHEGFGLPIGGVMAIEEK- 88 Query: 84 GYVSPSIVGSDIGCGMRVHLTTLHXXXXXXXXXXXXXXXAIEKYLPMEQQQRGTYSDIR- 142 G +S VG DI CG+R+ + L IE Y+P ++G + I Sbjct: 89 GVISAGAVGYDINCGVRLIRSDLEADYFTKDILYKLIER-IEHYVPTGIGKKGRHKGITR 147 Query: 143 --LENIVRKGLHGLPNKYVPDSYTPKKSSALSHVEISKL-GFDEEILNELPDMAWHRGHR 199 +++V G+ V + KKS E KL G D ++ + + A RG Sbjct: 148 VIFDDVVHNGVEA-----VIKAGFGKKSDLEYIEEGGKLEGAD---ISAVSEEAQERGEE 199 Query: 200 QLGTLGGGNHFVXXXXXXXXXXXXXXXXXWGLRDGQIAVMIHSGSRAWGGMVNQFCIPAF 259 QLGTLGGGNHF+ +GL GQ+AVMIH+GSR +G + Sbjct: 200 QLGTLGGGNHFIEIQKVEEILEENLAEK-FGLFKGQLAVMIHTGSRGFGHQIATDYTKIL 258 Query: 260 AKVMGQLGLGSADPRLIYAPLAHPQARRYVNLMYSALNYAVVNRHLIAYAVREGFRDVFG 319 + + G+ + L AP+ + + Y M +A+N+A NR +I + V F DV Sbjct: 259 WEAAKRYGIEVPEKGLAAAPIKSKEGQNYYKAMAAAVNFAFSNRQIIMFDVIRAFEDVLK 318 Query: 320 PKCE---LRTLYDLMHNYAWQEQTAAGTKFVHRKGATRALPAGHPDNPRPYAATGHPALI 376 E + +YD+ HN A E VHRKGATRALPAGHP NP Y TGHPALI Sbjct: 319 KSEEEMGFKLVYDVAHNIAKWEVHGGKRMLVHRKGATRALPAGHPQNPPSYRDTGHPALI 378 Query: 377 PGSMGTASYIMVGQPGGEENYYSICHGAGRIRSRSATKRLVSVNDFSKSLRVGREDEIVV 436 PGSMGT SY++VG E +YS+ HGAGR SR+ K+ +S +F +S+ ++V Sbjct: 379 PGSMGTGSYVVVGTEKAAETFYSVNHGAGRRLSRNQAKK-ISKEEFERSM-----GDVVY 432 Query: 437 NQHSLESIIDESPQAYKNVDEIIESVTGAGLAAVVAKCKPLAAIKG 482 N S + I+DESP AYK+V+ ++ G+ VAK PLA +KG Sbjct: 433 NVRSYKDIVDESPLAYKDVETVVSVFEERGITIPVAKLIPLAVVKG 478 >ref|NP_393759.1| conserved hypothetical protein [Thermoplasma acidophilum] emb|CAC11424.1| conserved hypothetical protein [Thermoplasma acidophilum] Length = 466 Score = 224 bits (571), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 158/467 (33%), Positives = 232/467 (49%), Gaps = 38/467 (8%) Query: 29 VYASEQLFA-TLDYKVLEMANNNLQIPNIEYMSYT-PDVHVGVGTCIGTTAVWDAADGYV 86 VY+SE+LF ++D L+ N ++P I SY PD+H+G G IG A +DA G + Sbjct: 25 VYSSEELFKKSVDEGSLKQVMNVAKLPGIIKASYAMPDIHLGYGFPIGGVAAFDAETGII 84 Query: 87 SPSIVGSDIGCGMRVHLTTLHXXXXXXXXXXXXXXXAIEKYLPMEQQQRGTYSDIRLENI 146 SP VG DI CG+ + T + IE + ++ S L I Sbjct: 85 SPGGVGYDINCGVALVSTGISFDEFMPKIKEVTDDLFIEIPSGLTSRKGLKVSSSDLNEI 144 Query: 147 VRKGL-----HGLPNKYVPDSYTPKKSSALSHVEISKLGFDEEILNELPDMAWHRGHRQL 201 +R GL H L + D S S +SK A RG Q+ Sbjct: 145 LRSGLKWAYEHDLATRDDMDHTEDHGSIENSGENVSK-------------AAQQRGMSQI 191 Query: 202 GTLGGGNHFVXXXXXXXXXXXXXXXXXWGLRDGQIAVMIHSGSRAWGGMVNQFCIPAFAK 261 GTLG GNHF+ +G++ ++ VM+H+GSR G V I + Sbjct: 192 GTLGAGNHFLEVQKVSQIFDYDLAGK-FGIKMNEVTVMVHTGSRGLGHQVATDYIRMLRE 250 Query: 262 VMGQLGLGSADPRLIYAPLAHPQARRYVNLMYSALNYAVVNRHLIAYAVREGFRDVFGPK 321 + ++DP LI AP+ P +Y++ M SA N+A VNR + Y +R F FG Sbjct: 251 --ADYSVKTSDPELISAPVRSPIGEKYIDAMRSAANFAFVNRQIAIYRIRSVFEKHFG-- 306 Query: 322 CELRTLYDLMHNYAWQEQTAAGTK----FVHRKGATRALPAGHPDNPRPYAATGHPALIP 377 R +Y L HN A +E + VHRKGATRA PAG + P+ TGHP LIP Sbjct: 307 VTPRLIYSLAHNIAKEENHVVDGESMKVIVHRKGATRAFPAGKASS--PFEDTGHPVLIP 364 Query: 378 GSMGTASYIMVG-QPGGEENYYSICHGAGRIRSRS-ATKRLVSVNDFSKSLRVGREDEIV 435 GSMGTASY++VG + ++++ + CHG+GR+ SR+ A K+ + K L +E + Sbjct: 365 GSMGTASYVLVGLRDNLDKSFGTTCHGSGRVLSRNQAVKKYAGL--VEKEL---QEKNVY 419 Query: 436 VNQHSLESIIDESPQAYKNVDEIIESVTGAGLAAVVAKCKPLAAIKG 482 + + + +E+P++YKNVDE++++V GA LA V K P++ +KG Sbjct: 420 ARPATKQVLYEEAPESYKNVDEVVDAVYGASLAKPVVKMIPVSVVKG 466 >ref|NP_069696.1| conserved hypothetical protein [Archaeoglobus fulgidus DSM 4304] pir||F69357 conserved hypothetical protein AF0862 - Archaeoglobus fulgidus gb|AAB90372.1| conserved hypothetical protein [Archaeoglobus fulgidus DSM 4304] Length = 482 Score = 218 bits (554), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 155/462 (33%), Positives = 227/462 (49%), Gaps = 20/462 (4%) Query: 30 YASEQLFATLDYKVLEMANNNLQIPNIEYMSYT-PDVHVGVGTCIGTTAVWDAADGYVSP 88 Y S +L L+ +E A N +P I+ S PDVHVG G IG A +D +G VSP Sbjct: 32 YISRKLMQILEKDAVEQAANVATMPGIQVASLVMPDVHVGYGFPIGGVAGFDVNEGVVSP 91 Query: 89 SIVGSDIGCGMRVHLTTLHXXXXXXXXXXXXXXXAIEKYLPMEQQQRGTYSDIRLENIVR 148 VG DI CG+R+ + L+ + + + R SD L+ I Sbjct: 92 GGVGFDINCGVRLLRSNLNVEDVKPLIKKLIDELFVAVPSGVGSEGRLRVSDRELDEIFV 151 Query: 149 KGLHGLPNKYVPDSYTPKKSSALSHVEISKLGFDEEILNELPDMAWHRGHRQLGTLGGGN 208 +G V + Y ++ E + G E++++ A RG QLGTLG GN Sbjct: 152 EGARWA----VENGYGYERDLKHCEEEGALEGARPEVVSK---KARDRGRPQLGTLGSGN 204 Query: 209 HFVXXXXXXXXXXXXXXXXXWGLRDGQIAVMIHSGSRAWGGMVNQFCIPAFAKVMGQLGL 268 HF+ +G+ +G + VMIH GSR G V + + + + G+ Sbjct: 205 HFLEVQYVDKVFDEKVAAK-FGIEEGMVTVMIHCGSRGLGHQVCTDFLEVLDRAVKKYGI 263 Query: 269 GSADPRLIYAPLAHPQARRYVNLMYSALNYAVVNRHLIAYAVREGFRDVFGPKCE---LR 325 D +L AP+ + + Y M ++ NYA NR +IA+ VRE F+ V G + + Sbjct: 264 KLPDRQLACAPINSKEGQDYFAGMAASANYAWCNRQIIAHWVRETFQKVMGMSEDDLGME 323 Query: 326 TLYDLMHNYA-WQEQTAAGTKF---VHRKGATRALPAGHPDNPRPYAATGHPALIPGSMG 381 +YD+ HN A ++E G K VHRKGATRA G + P Y G P LIPGSMG Sbjct: 324 LVYDVAHNIAKFEEHRVDGKKMKLCVHRKGATRAFGPGLKEVPEDYRDVGQPVLIPGSMG 383 Query: 382 TASYIMVG-QPGGEENYYSICHGAGRIRSRSATKRLVSVNDFSKSLRVGREDEIVVNQHS 440 T SYI+VG + EE + S CHG+GR+ SR+A KR + N ++L I V Sbjct: 384 TPSYILVGTEKAMEETFGSTCHGSGRVMSRAAAKRKLRGNVVKQNL---ERKGIYVRATH 440 Query: 441 LESIIDESPQAYKNVDEIIESVTGAGLAAVVAKCKPLAAIKG 482 + +E+P+AYK D++++ V AG++ +VA+ +PL KG Sbjct: 441 GALLAEEAPEAYKLSDDVVDVVHRAGISKLVARLRPLGVAKG 482 >ref|NP_229158.1| conserved hypothetical protein [Thermotoga maritima] pir||E72265 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gb|AAD36428.1| conserved hypothetical protein [Thermotoga maritima] Length = 474 Score = 215 bits (548), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 161/474 (33%), Positives = 227/474 (47%), Gaps = 32/474 (6%) Query: 25 GDLKVYA-----SEQLFATLDYKVLEMANNNLQIPNI-EYMSYTPDVHVGVGTCIGTTAV 78 GD+KV A +E + + ++ N +P I +Y PD+H G G IG A Sbjct: 17 GDMKVDAIIFTDAESVNDPQFREAMKQLMNVATLPGIVKYALAMPDIHWGYGFPIGGVAA 76 Query: 79 WDAADGYVSPSIVGSDIGCGMRVHLTTLHXXXXXXXXXXXXXXXAIEKYLPMEQQQRGTY 138 +D +G +SP VG DI CG+R+ T L AI +++P G+ Sbjct: 77 FDVKEGIISPGGVGFDINCGVRLMKTDL--TYEDVKDRMRSLVEAIYEFVP---AGVGST 131 Query: 139 SDIRLENIVRKGLHGLPNKYVPDSYTPKKSSALSHVEISKLGFDEEILNELP----DMAW 194 DI L G GL V + KS ++ ++ +I P + A+ Sbjct: 132 GDIVL------GKKGLRKVLVEGAEWAVKSGYGLEEDLERIEDGGKIHPADPSYVSEEAF 185 Query: 195 HRGHRQLGTLGGGNHFVXXXXXXXXXXXXXXXXXWGLRDGQIAVMIHSGSRAWGGMVNQF 254 RG +LGTLG GNHFV +GL G I VMIHSGSR +G V Sbjct: 186 ERGSDELGTLGAGNHFVEVQMVQEIYDEELAEF-FGLEIGTITVMIHSGSRGFGHQVATD 244 Query: 255 CIPAFAKVMGQLGLGSADPRLIYAPLAHPQARRYVNLMYSALNYAVVNRHLIAYAVREGF 314 I + + D +LI AP HP + Y + M A NYA NR ++ + VR+ F Sbjct: 245 YIRLMRDNLKEHNKNLPDKQLINAPFEHPLGQAYYSAMNCAANYAFANREILGHLVRKAF 304 Query: 315 RDVFGPKCELRTLYDLMHNYAWQEQTAAGTK----FVHRKGATRALPAGHPDNPRPYAAT 370 VFG + +YD+ HN A E+ K VHRKGATR+L G P Y Sbjct: 305 WKVFGRDTRVDLIYDVAHNIAKVEEYEVDGKRRKLVVHRKGATRSLGPGSEKVPSIYREV 364 Query: 371 GHPALIPGSMGTASYIMVGQPGGEENYY-SICHGAGRIRSRSAT-KRLVSVNDFSKSLRV 428 G P +IPG MGTASY++VG EE + S HGAGR+ RSA K+L D+ + L Sbjct: 365 GQPVIIPGDMGTASYLLVGTKKAEEKTFGSTAHGAGRVLGRSAALKKL----DYREVLDE 420 Query: 429 GREDEIVVNQHSLESIIDESPQAYKNVDEIIESVTGAGLAAVVAKCKPLAAIKG 482 E IVV S +++++E+P+ YK+VD +++ V G++ VA+ PL +KG Sbjct: 421 LAEKNIVVMSKSKKTLVEEAPEVYKDVDRVVQIVHEIGISRKVARMIPLGVVKG 474 >ref|ZP_00001116.1| COG1690: Uncharacterized conserved protein [Ferroplasma acidarmanus] Length = 475 Score = 206 bits (525), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 155/477 (32%), Positives = 229/477 (48%), Gaps = 35/477 (7%) Query: 20 LALPGGDLKVYASEQLFATL-DYKVLEMANNNLQIPNIEYMSYT-PDVHVGVGTCIGTTA 77 + +PG +Y S+ L D + ++ + +P I S PD+H+G G IG A Sbjct: 20 MRVPG---TIYISQDLLGNFTDDEPIKQVMHVASLPGIVKSSMAMPDIHLGYGFPIGGVA 76 Query: 78 VWDAADGYVSPSIVGSDIGCGMRVHLTTLHXXXXXXXXXXXXXXXAIEKYLPMEQQQRGT 137 +D DG +SP VG DI CG V L T + I K +P + + Sbjct: 77 AFDYDDGIISPGGVGYDINCG--VSLITTNIDYDEARDKINILLDEINKTVPAGIDYKSS 134 Query: 138 YS-DIRLEN-IVRKGLHGLPNKYVPDSYTPKKSSALSHVEISKLGFDEEILNELPDMAWH 195 + I EN I+ G+ N + Y ++ + E K+ D ++ + + A Sbjct: 135 FRISIDDENEILSSGIEWAYN----NGYATREDIERTE-ENGKMLSD---ISGVSEKAIK 186 Query: 196 RGHRQLGTLGGGNHFVXXXXXXXXXXXXXXXXXWGLRDGQIAVMIHSGSRAWGGMVNQFC 255 RG +LGTLG GNHF+ +A+M+H+GSR G +Q Sbjct: 187 RGKNELGTLGAGNHFLEMDRIESIMDEAKAKKFGINNKNNLAIMVHTGSRGLG---HQVA 243 Query: 256 IPAFAKVMGQ-LGLGSADPRLIYAPLAHPQA-RRYVNLMYSALNYAVVNRHLIAYAVREG 313 ++ + + S D R + + H + + Y+N M +A N+ VNR +I Y +R+ Sbjct: 244 TDYLMRLNEEDSSIKSEDDRQLISAYIHSRTGQDYLNAMNAAANFGFVNRQIITYKIRKA 303 Query: 314 FRDVFGPKCE---LRTLYDLMHNYAWQE-QTAAGTK---FVHRKGATRALPAGHPDNPRP 366 F +FG E + TLY L HN A E G K VHRKGATRALPA Sbjct: 304 FEKIFGEDFEHLGIETLYSLAHNMAKAEIHNVDGNKRKLMVHRKGATRALPAYASSGY-- 361 Query: 367 YAATGHPALIPGSMGTASYIMVGQPGGEE-NYYSICHGAGRIRSRSATKRLVSVNDFSKS 425 + TGHP +IPG+MG SY+MVG PG EE + S CHGAGR+ SR + D Sbjct: 362 FNETGHPVIIPGNMGGPSYVMVGMPGNEEITFSSSCHGAGRVLSRKRANEQFNAEDVEME 421 Query: 426 LRVGREDEIVVNQHSLESIIDESPQAYKNVDEIIESVTGAGLAAVVAKCKPLAAIKG 482 L+ I + + ++II+ESP +YKN+DE++ + GA +AA VA+ P+A +KG Sbjct: 422 LK---SRGIYLRATTKKAIIEESPGSYKNIDEVVRVINGAKIAAPVARLMPVAVMKG 475 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.136 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 705,088,842 Number of extensions: 28920159 Number of successful extensions: 63474 Number of sequences better than 1.0e-05: 118 Number of HSP's gapped: 63052 Number of HSP's successfully gapped: 127 Length of query: 484 Length of database: 757,237,578 Length adjustment: 130 Effective length of query: 354 Effective length of database: 404,274,708 Effective search space: 143113246632 Effective search space used: 143113246632 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)