BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0231.0002.p (603 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gb|AAN87474.1| Cobyric acid synthase [Heliobacillus mobilis] 442 e-122 ref|ZP_00100020.1| COG1492: Cobyric acid synthase [Desulfitobact... 438 e-121 ref|ZP_00180573.1| hypothetical protein Mther148001 [Moorella th... 435 e-120 ref|NP_930221.1| Cobyric acid synthase [Photorhabdus luminescens... 425 e-117 ref|NP_456573.1| putative cobyric acid synthase [Salmonella ente... 425 e-117 >gb|AAN87474.1| Cobyric acid synthase [Heliobacillus mobilis] Length = 524 Score = 442 bits (1136), Expect = e-122, Method: Compositional matrix adjust. Identities = 241/499 (48%), Positives = 321/499 (64%), Gaps = 18/499 (3%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGT+S+VGKS++ A+ RI +DG + PFKSQNMALNSYVT DG E+GRAQ +QAEA Sbjct: 6 MLQGTSSNVGKSVLATALCRIFLQDGQKVVPFKSQNMALNSYVTRDGGEMGRAQVVQAEA 65 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 G+ MNPILLKP+G+ S+Q++V G P +SAR+Y ++ +A T+ L Sbjct: 66 AGLDPHVKMNPILLKPTGQASSQVIVLGRPVGNISARQYHLEYATQAVDTIQACLDEFHE 125 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 YD++++EGAGSPAE+NLKARDI NM +A ADAPVLLVADIDRGG A +VGTL LL+P Sbjct: 126 QYDVIVIEGAGSPAEVNLKARDIANMRVAKMADAPVLLVADIDRGGALASVVGTLALLDP 185 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 E+ R+KG +INKFRGD+SLLQP +D+LE+ T PV+GV+P+ + I+ EDSV LE Sbjct: 186 DEQERIKGIVINKFRGDISLLQPAIDFLEEYTKKPVVGVVPYFKGVHIQEEDSVALEKPI 245 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 + G+ LD+AVIR PRISNFTDFD L E VRYV LG PD++I+PGTKN Sbjct: 246 TEVPT--GEMLDIAVIRLPRISNFTDFDALSTEGAAQVRYVEAPGRLGRPDMVIIPGTKN 303 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T D+ +L++ G E I A +G + GICGGYQ+LG ++ DP VES+ P GLG Sbjct: 304 TIEDMLWLQKTGLTEEIRAVAEKGIL-VWGICGGYQILGKEIQDPQGVESSVP-VVAGLG 361 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPL--PLYGGEAASATAAELPVEGYEIHMGTTTNHD 418 L + T+ +K T A+ + P PL G L V+GYEIHMG + Sbjct: 362 LLDMVTTMEAEKVTQLASATICGHGPYLGPLQG----------LSVQGYEIHMGQSVASS 411 Query: 419 PASVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAPL 478 A + +G + +G +G V G+YLHG+F ND+LR L+ LR+ KGL P+ Sbjct: 412 EAKPFCRIERRGEELVDVIDGIVDADGLVIGSYLHGIFDNDSLRHHLLNTLRRKKGLEPI 471 Query: 479 --GQTFSAAALREQEFDRL 495 S A +EQ+++RL Sbjct: 472 NFASAASVAERKEQDYNRL 490 >ref|ZP_00100020.1| COG1492: Cobyric acid synthase [Desulfitobacterium hafniense] Length = 514 Score = 438 bits (1127), Expect = e-121, Method: Compositional matrix adjust. Identities = 251/499 (50%), Positives = 322/499 (64%), Gaps = 21/499 (4%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 MIQGT+S+VGKS++ AA RI ++GY APFK+QNMALNS++T G E+GRAQ +QA+A Sbjct: 11 MIQGTSSNVGKSVLAAAFCRIFYQEGYHVAPFKAQNMALNSFITRSGGEMGRAQVVQAQA 70 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 G+ MNP+LLKP+G +Q++V G LSA +Y + + V +AL L Sbjct: 71 AGLEPDVRMNPVLLKPTGHTGSQVIVLGKAQGTLSALKYHGDYQRKTWPIVEEALHELLE 130 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 ++IV++EGAGSPAE+NLK DIVNM +A A APVLLVADIDRGG A +VGTLELLEP Sbjct: 131 EHEIVVIEGAGSPAEVNLKQNDIVNMRVAKEAQAPVLLVADIDRGGALASVVGTLELLEP 190 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLE--G 238 ER V+G ++NKFRGD+ LLQP LD+LE+RTGIPV+GV+PF + +I EDSVVLE Sbjct: 191 EERQLVQGIVMNKFRGDIKLLQPALDFLEERTGIPVVGVVPFYDQFKIPEEDSVVLEEQN 250 Query: 239 TSGRLHAE-RGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPG 297 TS R + R + LDVAVIR P +SNFTDFDP EDEPD +RYV ELG PD +I+PG Sbjct: 251 TSKRDQGKSRDEALDVAVIRLPYLSNFTDFDPFEDEPDVILRYVREPSELGEPDCVIIPG 310 Query: 298 TKNTAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGERE 357 +KNT +DL +L E G E I + + GICGGYQMLG + DP ES + E Sbjct: 311 SKNTLSDLRFLWESGLGEKIIKFWQEDV-PIIGICGGYQMLGRIVRDPLGTES-DLKEIA 368 Query: 358 GLGFLPLSTSFLRQKTTVRATGLLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTTTNH 417 GLG LP+ T F K TV++ G + GGE A + GYEIHMG + Sbjct: 369 GLGILPMETEFELDKHTVQSRG--------KVVGGELFLARCQGTEITGYEIHMGRSQGE 420 Query: 418 DPASVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSK-GLA 476 SLF+++ + + G G G GTYLHG+F ND LR A L+ L + + G Sbjct: 421 G----HSLFEIEAQETAY---GDGMSAGSAVGTYLHGIFDNDPLRTALLEWLWERRGGTR 473 Query: 477 PLGQTFSAAALREQEFDRL 495 P+G+T S AA+REQ F+ L Sbjct: 474 PVGETMSQAAIREQSFNEL 492 >ref|ZP_00180573.1| hypothetical protein Mther148001 [Moorella thermoacetica ATCC 39073] Length = 517 Score = 435 bits (1119), Expect = e-120, Method: Compositional matrix adjust. Identities = 251/501 (50%), Positives = 319/501 (63%), Gaps = 21/501 (4%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGT+S+VGKS++ AA+ RI R+GYR +PFKSQNMALNS T DG E+GRAQ +QA A Sbjct: 6 MLQGTSSNVGKSVLAAALCRIFHRNGYRVSPFKSQNMALNSGATPDGGEMGRAQIVQAMA 65 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 G+ +MNPILLKP+ S+Q++V G P L AREY F + S V +A L Sbjct: 66 AGVVPRVEMNPILLKPTAHASSQVIVLGRPVGNLGAREYHGHFNQKLWSRVEEAYAFLER 125 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 ++I+++EGAGSPAEINLKA +I NM +A A APVLLVADIDRGG A +VGTLELLEP Sbjct: 126 EFEIIVIEGAGSPAEINLKAGEIANMRVARMAGAPVLLVADIDRGGALAAVVGTLELLEP 185 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 ER V G IINKFRGDL LL+P LD+LE RTG PVLGV+PFLP + EDSVVLEG + Sbjct: 186 EERVMVAGIIINKFRGDLDLLKPALDFLESRTGKPVLGVIPFLPDHGLPEEDSVVLEGVT 245 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 GR + E+++AVI+ P ISNFTDFD LE E +RYV A +LG PD++ILPG+KN Sbjct: 246 GR--STGAGEVEIAVIKLPCISNFTDFDALEREKGVNLRYVEAASDLGNPDLVILPGSKN 303 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T DL +LR QG AI +GT + GICGGYQMLG ++ DP VE+ + +GL Sbjct: 304 TIGDLLWLRCQGLETAIKELAGRGT-PIIGICGGYQMLGKEIRDPEHVET-DVEMIKGLD 361 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPL--PLYGGEAASATAAELPVEGYEIHMGTTTNHD 418 LP+ T F K T + G++ P PL G E V+GYEIHMG + D Sbjct: 362 LLPIKTVFQTSKATNQVRGVVTGSGPFLGPLQGQE----------VQGYEIHMGASFLLD 411 Query: 419 PASVRSLFQLKGPDGSMQ--QEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLA 476 R F++ G + +G EGR+WGTY+HG+ ND+LR + LR +GL Sbjct: 412 G---RPAFKITSRGGRLVTLDDGALAGEGRIWGTYIHGILDNDSLRHQVISVLRARRGLP 468 Query: 477 PLGQTFSAAALREQEFDRLGG 497 + A +E+ D L G Sbjct: 469 ARPGMLNFMAEQERRLDILAG 489 >ref|NP_930221.1| Cobyric acid synthase [Photorhabdus luminescens subsp. laumondii TTO1] emb|CAE15361.1| Cobyric acid synthase [Photorhabdus luminescens subsp. laumondii TTO1] Length = 512 Score = 425 bits (1092), Expect = e-117, Method: Compositional matrix adjust. Identities = 241/499 (48%), Positives = 318/499 (63%), Gaps = 22/499 (4%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGTASDVGKS++ A + RI +DGYR APFKSQNMALNS +T +G E+GRAQ QAEA Sbjct: 6 MLQGTASDVGKSVLVAGLCRIFVQDGYRCAPFKSQNMALNSGITINGEEMGRAQIFQAEA 65 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 GI MNP+LLKP+ E AQ+V+ G +++A EY + + P + + + L + Sbjct: 66 AGIEPDVRMNPVLLKPTSERKAQVVLMGKVACSMNAVEYHQ-YKPSLQQQICEVFHSLAS 124 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 YD++++EGAGSPAEINL+ RDIVNM +A DAPVLLVADIDRGGVFA + GTL LL P Sbjct: 125 EYDVIVLEGAGSPAEINLRDRDIVNMGMAEMVDAPVLLVADIDRGGVFAAIYGTLALLRP 184 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 E+ARVKG IINKFRGD+SLLQPG++ +E TG+PVLGV+P+L + +E ED V L+ + Sbjct: 185 AEKARVKGVIINKFRGDISLLQPGIEQIEALTGVPVLGVMPWLD-IDLEDEDGVALQ--T 241 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 G+ K LD+ VIR P I+NFTDF+ L +PD +RYV+ L D+IILPG+KN Sbjct: 242 GKYDGATEKALDITVIRLPHIANFTDFNALAVQPDVRLRYVTQPSALQPSDLIILPGSKN 301 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T DL +LR+ G +A+ A +Q + GICGGYQMLG +++D VES + +GLG Sbjct: 302 TLGDLQWLRQNGLADALLTA-HQAGVPVIGICGGYQMLGKRIID--GVESGIE-QMDGLG 357 Query: 361 FLPLSTSFLRQKTTVRATG--LLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTT-TNH 417 L + T F +K T R G LLA LP + E P+ GYEIHMG++ Sbjct: 358 LLDMETRFAHEKVTTRVNGNCLLA----LP-----GLLSECVEQPIRGYEIHMGSSLLGA 408 Query: 418 DPASVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAP 477 D + + G G +G EG V G+Y+HGLF + RA L+ LRQ KGLA Sbjct: 409 DATPFIDITERNGQSGGW-CDGAVNREGSVMGSYIHGLFDSANFTRALLNALRQRKGLAA 467 Query: 478 L-GQTFSAAALREQEFDRL 495 G+ ++ +FD L Sbjct: 468 YQGEILDYTHYKQTQFDLL 486 >ref|NP_456573.1| putative cobyric acid synthase [Salmonella enterica subsp. enterica serovar Typhi] ref|NP_804690.1| putative cobyric acid synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2] sp|Q8Z5N6|COBQ_SALTI Cobyric acid synthase pir||AF0757 probable cobyric acid synthase cbiP [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) emb|CAD02380.1| putative cobyric acid synthase [Salmonella enterica subsp. enterica serovar Typhi] gb|AAO68539.1| putative cobyric acid synthase [Salmonella enterica subsp. enterica serovar Typhi Ty2] Length = 506 Score = 425 bits (1092), Expect = e-117, Method: Compositional matrix adjust. Identities = 239/495 (48%), Positives = 315/495 (63%), Gaps = 18/495 (3%) Query: 1 MIQGTASDVGKSLVTAAIGRIMTRDGYRTAPFKSQNMALNSYVTEDGREIGRAQGMQAEA 60 M+QGTASDVGKS++ A + RI +DG RTAPFKSQNMALNS +T DG+E+GRAQ QAEA Sbjct: 6 MLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQAEA 65 Query: 61 FGITATTDMNPILLKPSGEMSAQIVVHGVPHTALSAREYREKFLPEAKSTVMDALGRLRA 120 GIT MNP+LLKP+ + AQ+V+ G T + A Y + + P + ++ L Sbjct: 66 AGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAVSYHD-YKPRLREQILAVYNSLAQ 124 Query: 121 AYDIVLMEGAGSPAEINLKARDIVNMNLAGWADAPVLLVADIDRGGVFAFLVGTLELLEP 180 YD++++EGAGSPAEINL+ RDIVNM +A A PV+LVADIDRGGVFA + GTL LL Sbjct: 125 EYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPVILVADIDRGGVFAAIYGTLALLHK 184 Query: 181 HERARVKGFIINKFRGDLSLLQPGLDWLEQRTGIPVLGVLPFLPRLRIEAEDSVVLEGTS 240 ER RVKG IINKFRGD++LL G++ +E TG+PVLGV+P+L + +E ED V L+ Sbjct: 185 QERDRVKGVIINKFRGDVALLYSGIEQIESLTGVPVLGVMPWLD-VDLEDEDGVALQNDK 243 Query: 241 GRLHAERGKELDVAVIRYPRISNFTDFDPLEDEPDTAVRYVSTAVELGTPDVIILPGTKN 300 R +A R ++ +A+++ P ISNFTDF+ L +PD +RY+ L D++ILPG+KN Sbjct: 244 YRGNAPR--DITIAIVQLPHISNFTDFNALAAQPDVRIRYIRRPEALTDADLVILPGSKN 301 Query: 301 TAADLDYLREQGFPEAIAAALNQGTRQLAGICGGYQMLGLKLLDPHAVESAEPGEREGLG 360 T +DL +LRE G +A+ QG + GICGGYQMLG ++D VES G + GLG Sbjct: 302 TLSDLAWLRESGMADAVLQTHRQGV-PVMGICGGYQMLGDTIVDE--VESG-LGTQPGLG 357 Query: 361 FLPLSTSFLRQKTTVRATGLLAQDHPLPLYGGEAASATAAELPVEGYEIHMGTTTNHDPA 420 L T F + KTT + ++ + P L A AA LPV GYEIHMG T + Sbjct: 358 LLNTITRFAQDKTTTQVNATMSGELPGWL-------AAAAGLPVRGYEIHMGETVLQEGC 410 Query: 421 SVRSLFQLKGPDGSMQQEGWGTPEGRVWGTYLHGLFHNDALRRAWLDGLRQSKGLAPLGQ 480 Q +G +G T +G +GTYLHGLF +DA RA ++GLR KGLAP Sbjct: 411 CTAMTLQ---KNGCSVADGAVTADGLAFGTYLHGLFDSDAFTRAVVNGLRARKGLAPWET 467 Query: 481 TFSAAALREQEFDRL 495 TF A + ++FD L Sbjct: 468 TFCYAEHKARQFDLL 482 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.137 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 908,009,467 Number of extensions: 39155177 Number of successful extensions: 86973 Number of sequences better than 1.0e-05: 217 Number of HSP's gapped: 86100 Number of HSP's successfully gapped: 217 Length of query: 603 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 472 Effective length of database: 401,559,609 Effective search space: 189536135448 Effective search space used: 189536135448 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)