BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0210.0008.p (575 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halo... 262 2e-68 ref|NP_242775.1| two-component sensor histidine kinase [Bacillus... 166 1e-39 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 159 2e-37 ref|NP_815880.1| sensor histidine kinase [Enterococcus faecalis ... 156 1e-36 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 143 1e-32 >ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halodurans] pir||F83913 hypothetical protein BH2110 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05829.1| BH2110~unknown conserved protein [Bacillus halodurans] Length = 585 Score = 262 bits (669), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 169/566 (29%), Positives = 295/566 (52%), Gaps = 14/566 (2%) Query: 1 VLVPILSINALFYVQISRNVEARERENLEISVDRVVYDLMQIVNECVAISNTVAADRPYM 60 V +PIL N +FY + N++A++ +++E+ VD++ + V++ + IS+ + Sbjct: 25 VFLPILLTNIIFYNVTANNIKAQKMDDIELVVDQITNEFNNAVDQAIGISSGFYTNTRIY 84 Query: 61 EMMDYAYPDNEAYYDAYNDSLKDKLRQYSNLHSYISWMGIYTSNPTIQNGNSYFILSDAD 120 + + Y Y +AY+ L++ R +S L+ I + YT NP+ L++ Sbjct: 85 DFFETEYETAIDYIEAYDFYLREYSR-FSPLYYSIQSISFYTDNPSFIYAGGIRPLTEHT 143 Query: 121 KRSEWYRKISSSTDKVLLTSYQGTNPLNPPQQEVLVSLIRKLDNFTGQ-PYTKYLRIDLR 179 K +WYR ++ + +++ + NP L S+IR+LD + + K +RIDL Sbjct: 144 KEEKWYRLLTEANHPIIIRT-------NPATDSGLFSVIRELDYHKNKYNHKKIVRIDLN 196 Query: 180 LNNMQEVFQKERDYLDFKLLDEKNRVVLASDRSFSSLDASALLNVDTSLDQPPKQIVRA- 238 ++++F + LL+ + + +S+ + + L+ D +L+ P I Sbjct: 197 PLTIKQIFNNAAFTGEVYLLNGERNIEFSSNEEVNW--RTEQLHFD-ALEFPEDTIFTKE 253 Query: 239 -LSSAAYTTGWRLVGTPEGRKINHEMDRALRNSXXXXXXXXXXXXXXXXXXXRSYNLRVR 297 + S Y GWR+ GT +I E+ ++ +S + R+ Sbjct: 254 RMLSQNYLEGWRVAGTISENEILEELYKSREFIVILASINLLFPTLLIVLISKSIHSRLL 313 Query: 298 LLYKHMKLVKYEQFESIDMYEGKDEIGGLIRSFNLMTGKIRNLINDVYKLEIQKKDLELE 357 + KHMK +K ++F+ I+ KDEIG L FN M+ I LIN+VY I+KKDL+L Sbjct: 314 RVLKHMKRMKKQKFDIINFPGDKDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQLR 373 Query: 358 RVRAELKYLESQVDPHFLFNTLNAILVICKKYKYEQVTDVIRNLALIMRRLLSWKDDLIT 417 +A+L L+SQ++PHFLFN L I + ++ +I+N+A I R L+W D +T Sbjct: 374 EKQAQLSALQSQINPHFLFNALETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDWVT 433 Query: 418 LEEEVSFIEMYLQIEKFRFQNRFSYVLDIEPEVLNCRIPKMSIQALVENSCKHGLQSVKW 477 + +E+ I +L+I+K+RF ++ Y LDI+ E + IP M VEN+ HG++SVK Sbjct: 434 VRDELCLIICFLEIQKYRFGDKMEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESVKE 493 Query: 478 AREVHVSASRNGTGLLIMVTDNGKGIEKEKLEWIKSHLETEEDTGQNVGLRNVYKRLMLY 537 + + +N ++ ++DNG G+++EKL + L+ EE+ G+NVG++NVY RL L+ Sbjct: 494 KGIIQIRVEKNDGEIVYEISDNGAGMDEEKLASLIETLKNEENMGENVGIKNVYYRLKLH 553 Query: 538 YNGKATFSIESTEYERTVITIQIPGE 563 Y FSI S + T + I++P E Sbjct: 554 YKNHFDFSINSRPGQGTTVQIKLPAE 579 >ref|NP_242775.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83888 two-component sensor histidine kinase BH1909 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05628.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 597 Score = 166 bits (420), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 141/546 (25%), Positives = 251/546 (45%), Gaps = 27/546 (4%) Query: 30 ISVDRVVYDLMQIVNECVAISNTVAADRPYMEMMDYAYPDNEAYYDAYND--SLKDKLRQ 87 ++V+RV +++N V I+N + D ++E+++ Y DAY + + L+ Sbjct: 55 VNVERVKERTTEVLNVPVLIANNLQFDERFIELVNQEYETTYDVVDAYLQYMNFTNYLQY 114 Query: 88 YSNLHSYISWMGIYTSNPTIQNGNSYFILSDADKRSEWYRKISSSTDKVLLTSYQGTNPL 147 YS +H+ M Y+ N ++ N N I + + EW+++ + D + + Sbjct: 115 YSEIHN----MKYYSENTSLMN-NWVIIPVEHEAGEEWFKE--AMADPAYYRWFYLEDET 167 Query: 148 NPPQQEVLVSLIRKLDNFTGQPYTKYLRIDLRLNNMQEVFQKERDYLDFKLLDEKNRVVL 207 Q +S++++L NF L I + + + Q+E ++DE+NR+ Sbjct: 168 KKNQ--AYLSMVKRL-NFLEYGSAGVLVITVDPRKLDRILQQES--FTTMIVDERNRIAA 222 Query: 208 ASDRSFSSLDASALLNVDTSLDQ------------PPKQIVRALSSAAYTTGWRLVGTPE 255 + R + D +++ + + P + IV L+ + +++ Sbjct: 223 TNQREYIGKDLHEVIDFHEMIQEGPAIYEGKMNGEPSQIIVDYLTLQMSQSELKIISIVT 282 Query: 256 GRKINHEMDRALRNSXXXXXXXXXXXXXXXXXXXRSYNLRVRLLYKHMKLVKYEQFESID 315 I + R + R+ L + + V ++ Sbjct: 283 KEHIMKDAKRLSIMGATVTMGGMAVAVLLIVHFSWLISKRLSHLSERINQVASGDLKTKI 342 Query: 316 MYEGKDEIGGLIRSFNLMTGKIRNLINDVYKLEIQKKDLELERVRAELKYLESQVDPHFL 375 + +GKDEIG L FN M +R+LI+ V++ QK+ LE + +LK L SQ++PHFL Sbjct: 343 VVDGKDEIGQLSVQFNQMVANLRSLIHQVHETNRQKRLLEKSQNEIKLKMLASQINPHFL 402 Query: 376 FNTLNAILVICKKYKYEQVTDVIRNLALIMRRLLSWKDDLITLEEEVSFIEMYLQIEKFR 435 FNTL +I + ++ V++ L +MR+ L I L E+ + YL+I+ FR Sbjct: 403 FNTLESIRMKSHMKGETEIAKVVKQLGKLMRKSLEVTGHHIPLRNELDMVRCYLEIQTFR 462 Query: 436 FQNRFSYVLDIEPEVLNCRIPKMSIQALVENSCKHGLQSVKWAREVHVSASRNGTGLLIM 495 + +R Y L I+P+ I + IQ LVEN+ HGL+ + V +S NG L ++ Sbjct: 463 YGDRLHYELYIDPQSEMVEILPLIIQPLVENAVIHGLERTEDGGTVTISTIVNGNDLTVI 522 Query: 496 VTDNGKGIEKEKLEWIKSHL-ETEEDTGQNVGLRNVYKRLMLYYNGKATFSIESTEYERT 554 V D+G G+++EKLE I++ L +E G +GL NV+KRL L Y + IES + + T Sbjct: 523 VNDDGCGMDEEKLEAIQNMLHHPQEVDGNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGT 582 Query: 555 VITIQI 560 + I Sbjct: 583 CVRFTI 588 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 159 bits (402), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 94/251 (37%), Positives = 150/251 (59%), Gaps = 10/251 (3%) Query: 317 YEGKDEIGGLIRSFNLMTGKIRNLINDVYKLEIQKKDLELERVRAELKYLESQVDPHFLF 376 Y KDEI +I+ +N M +I +LIN + KLEI K++ AELK LE+Q++PHFL+ Sbjct: 351 YHSKDEIAIVIKEYNRMVERINDLINRILKLEINKRE-------AELKALEAQINPHFLY 403 Query: 377 NTLNAILVICKKYKYEQVTDVIRNLALIMRRLLSWKDDLITLEEEVSFIEMYLQIEKFRF 436 NTL+ I +K K +++++I +L+ + R L+ ++ I + E IE YL ++ R+ Sbjct: 404 NTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRY 463 Query: 437 QNRFSYVLDIEPEVLNCRIPKMSIQALVENSCKHGLQSVKWAREVHVSASRNGTGLLIMV 496 +N+F Y + I E+L+ IPK+ +Q VEN+ HGL++ V V + G L ++ Sbjct: 464 KNKFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFII 523 Query: 497 TDNGKGIEKEKLEWIKSHLETEEDTGQNVG--LRNVYKRLMLYYNGKATFSIESTEYERT 554 DNG G+ +E LE +K +E+ E+ + VG +RNV +RL LYY K IES + E T Sbjct: 524 KDNGPGMSEETLEKLKRFIES-ENIEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGT 582 Query: 555 VITIQIPGELS 565 I++ +P +S Sbjct: 583 TISLILPESIS 593 >ref|NP_815880.1| sensor histidine kinase [Enterococcus faecalis V583] gb|AAO81950.1| sensor histidine kinase [Enterococcus faecalis V583] Length = 570 Score = 156 bits (394), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 86/246 (34%), Positives = 143/246 (58%), Gaps = 9/246 (3%) Query: 312 ESIDMYEGKDEIGGLIRSFNLMTGKIRNLINDVYKLEIQKKDLELERVRAELKYLESQVD 371 E ID + ++E+ + + N M + I+D+Y LEI+++D A ++ L+SQ++ Sbjct: 327 ERIDTNQVQEELNDIASAINFMVDSLDQYIHDIYTLEIKQRD-------AHMRALQSQIN 379 Query: 372 PHFLFNTLNAILVICKKYKYEQVTDVIRNLALIMRRLLSWKDDLITLEEEVSFIEMYLQI 431 PHFL+NTL I + + E++ DV+ + ++R ++ ++ TL EE+SF E Y+ + Sbjct: 380 PHFLYNTLEYIRMYALSRQQEELADVVYAFSTLLRNNIN-QEKTTTLAEEISFCEKYVYL 438 Query: 432 EKFRFQNRFSYVLDIEPEVLNCRIPKMSIQALVENSCKHGLQSVKWAREVHVSASRNGTG 491 + R+ ++F+Y +IE + + IPK IQ LVEN HG+ + + V A R G Sbjct: 439 YQMRYPDQFAYKFEIEETIADVEIPKFIIQPLVENYFVHGIDYQRQDNAIKVHAYREGEK 498 Query: 492 LLIMVTDNGKGIEKEKLEWIKSHL-ETEEDTGQNVGLRNVYKRLMLYYNGKATFSIESTE 550 +++ V DNGKGI +LE I+ L +TE DT Q++GLRNV++RL ++ +IE E Sbjct: 499 IIVAVVDNGKGITANRLEEIRERLNQTEIDTEQSIGLRNVHERLQRFFGESYGLTIEGKE 558 Query: 551 YERTVI 556 E T I Sbjct: 559 GEGTTI 564 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 143 bits (361), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 103/323 (31%), Positives = 165/323 (51%), Gaps = 8/323 (2%) Query: 239 LSSAAYTTGWRLVGTPEGRKINHEMDRALRNSXXXXXXXXXXXXXXXXXXXRSYNLRVRL 298 SS YT W L E +KI+ ++++ + S + Sbjct: 253 FSSVPYTENWILCIIVENKKIHTQINQIINLILFVGLILLLAAILLSIVISGSIVKPIHR 312 Query: 299 LYKHMKLVKYEQFESIDMYEGKDEIGGLIRSFNLMTGKIRNLINDVYKLEIQKKDLELER 358 L +M + F+S + DEI L + FN M I+ LIN VY++E QK+ Sbjct: 313 LKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQKRS----- 367 Query: 359 VRAELKYLESQVDPHFLFNTLNAILVICKKYKYEQVTDVIRNLALIMRRLLSWKDDLITL 418 AEL+ L+SQ++PHFL+NTL+ I +Y +V D+I L+ R LS + IT+ Sbjct: 368 --AELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITI 425 Query: 419 EEEVSFIEMYLQIEKFRFQNRFSYVLDIEPEVLNCRIPKMSIQALVENSCKHGLQSVKWA 478 +EV+ + YL+I+K R++++ SY +D++ + IPK+ +Q LVENS HGL+ K Sbjct: 426 SDEVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKLQKHK 485 Query: 479 REVHVSASRNGTGLLIMVTDNGKGIEKEKLEWIKSHLETEEDTGQNVGLRNVYKRLMLYY 538 ++VS S L I V DNG G++ E+L ++ +L +T GL N+ +RL L + Sbjct: 486 GIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLWESIETNH-YGLYNINERLKLAF 544 Query: 539 NGKATFSIESTEYERTVITIQIP 561 K + I+S T + ++IP Sbjct: 545 GKKYSIEIKSELKIGTQVLLRIP 567 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 808,733,409 Number of extensions: 33115486 Number of successful extensions: 113479 Number of sequences better than 1.0e-05: 186 Number of HSP's gapped: 113231 Number of HSP's successfully gapped: 186 Length of query: 575 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 444 Effective length of database: 401,559,609 Effective search space: 178292466396 Effective search space used: 178292466396 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)