BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0197.0017.p (251 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00097462.1| COG0789: Predicted transcriptional regulators... 218 1e-55 ref|NP_345238.1| transcriptional regulator, MerR family [Strepto... 95 1e-18 ref|NP_391541.1| transcriptional regulator [Bacillus subtilis] >... 95 1e-18 ref|NP_241274.1| transcriptional activator of multidrug-efflux t... 92 8e-18 ref|ZP_00119986.1| COG0789: Predicted transcriptional regulators... 91 2e-17 >ref|ZP_00097462.1| COG0789: Predicted transcriptional regulators [Desulfitobacterium hafniense] Length = 250 Score = 218 bits (554), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 114/240 (47%), Positives = 148/240 (61%), Gaps = 2/240 (0%) Query: 1 VLYTVKEVAVLSGTTVKTLHHYHKTGLLVPAEISEAGYRLYGMAELERLQQIMLYKELDF 60 +LYTVKEVA L+G TVKTLHHYHK GLL P EI++AGYRLYG ELERLQQI+ Y+ELDF Sbjct: 2 MLYTVKEVAGLAGVTVKTLHHYHKIGLLKPCEITDAGYRLYGAEELERLQQILFYRELDF 61 Query: 61 TLEQIGQLLKEEPDRLSILVXXXXXXXXXXXXIDMIIETLRKSVTSRERGEPMKDTEMFK 120 +L I + L+++P RL L +D +++T+ +S+ ++GE M+ + MF+ Sbjct: 62 SLSDIQKALEDQPGRLMCLTKQQELLIARRQRLDCLLKTIGESIVLTKKGEIMEKSAMFQ 121 Query: 121 GLASEQEWKAALQEQGEHLKETYDYDLSAKGAPIDVQHMNDXXXXXXXXXXXXXXXLRSG 180 GL ++ W AL EQ ++LK+ Y Y+L K Q MND LR+G Sbjct: 122 GLNAD-AWNTALAEQSQYLKDHYGYELP-KVETEQAQEMNDSAAEAKQFMDFLAEALRAG 179 Query: 181 VKAGDVSTAELIRKHLDFMGEHGHPASAADFAAQNRFFLGDDFHLRMLEGQQTGLAYYLS 240 K D + I +HL F+ +HGHP A FAAQ RFFL DDFH MLE QQ GL YYL Sbjct: 180 WKGNDPRLQKKIEEHLAFLKDHGHPVDAQTFAAQARFFLEDDFHRGMLESQQLGLCYYLC 239 >ref|NP_345238.1| transcriptional regulator, MerR family [Streptococcus pneumoniae TIGR4] pir||E95085 transcription regulator, MerR family [imported] - Streptococcus pneumoniae (strain TIGR4) emb|CAB59899.1| regulator of pmrA [Streptococcus pneumoniae] gb|AAK74878.1| transcriptional regulator, MerR family [Streptococcus pneumoniae TIGR4] Length = 246 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 57/129 (44%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Query: 2 LYTVKEVAVLSGTTVKTLHHYHKTGLLVPAEISEAGYRLYGMAELERLQQIMLYKELDFT 61 +Y +KE A LSG +VKTLHHY K GLLVP + SE GYR Y +LERLQ I+ YK L F+ Sbjct: 1 MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLK-SENGYRTYSQEDLERLQVILYYKYLGFS 59 Query: 62 LEQIGQLLKEE-PDRLSILVXXXXXXXXXXXXIDMIIETLRKSVTSRERGEPMKDTEMFK 120 LE+I +LLKEE D L L +D +I TL+K++ ++ M E F Sbjct: 60 LEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFT 119 Query: 121 GLASEQEWK 129 G + + K Sbjct: 120 GFSYQDNQK 128 >ref|NP_391541.1| transcriptional regulator [Bacillus subtilis] pir||C69661 transcription activator of multidrug-efflux transporter genes mta - Bacillus subtilis emb|CAA69863.1| putative transcriptional activator [Bacillus subtilis] emb|CAB15677.1| transcriptional regulator (MerR family) [Bacillus subtilis subsp. subtilis str. 168] Length = 257 Score = 95.1 bits (235), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 49/123 (39%), Positives = 79/123 (64%), Gaps = 3/123 (2%) Query: 3 YTVKEVAVLSGTTVKTLHHYHKTGLLVPAEISEAGYRLYGMAELERLQQIMLYKELDFTL 62 Y VK+VA +SG +++TLHHY LL P+ +++AGYRLY A+LERLQQI+ +KE+ F L Sbjct: 3 YQVKQVAEISGVSIRTLHHYDNIELLNPSALTDAGYRLYSDADLERLQQILFFKEIGFRL 62 Query: 63 EQIGQLLKEEP--DRLSILVXXXXXXXXXXXXIDMIIETLRKSVTSRERGEPMKDTEMFK 120 ++I ++L + P DR + L +D +I+T+ +++ S + GE M ++F Sbjct: 63 DEIKEML-DHPNFDRKAALQSQKEILMKKKQRMDEMIQTIDRTLLSVDGGETMNKRDLFA 121 Query: 121 GLA 123 GL+ Sbjct: 122 GLS 124 >ref|NP_241274.1| transcriptional activator of multidrug-efflux transporter genes [Bacillus halodurans] pir||H83700 transcription activator of multidrug-efflux transporter genes mta [imported] - Bacillus halodurans (strain C-125) dbj|BAB04127.1| transcriptional activator of multidrug-efflux transporter genes [Bacillus halodurans] Length = 255 Score = 92.4 bits (228), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 52/119 (43%), Positives = 71/119 (59%), Gaps = 1/119 (0%) Query: 5 VKEVAVLSGTTVKTLHHYHKTGLLVPAEISEAGYRLYGMAELERLQQIMLYKELDFTLEQ 64 VKEVA L GT+V+TLHHY + GLL+P E +EAGYRLY LE LQQI+ +KEL F+L+Q Sbjct: 5 VKEVAELVGTSVRTLHHYDEIGLLIPDETTEAGYRLYSDDNLEMLQQILFFKELGFSLKQ 64 Query: 65 IGQLLKEEP-DRLSILVXXXXXXXXXXXXIDMIIETLRKSVTSRERGEPMKDTEMFKGL 122 I +++ DRL L ID ++ET+ K++ + M + E F G Sbjct: 65 IKEIVYSPTFDRLEALSLHRNMLLEKRSRIDQMVETIDKTIKHLKGEIHMTNEEKFAGF 123 >ref|ZP_00119986.1| COG0789: Predicted transcriptional regulators [Cytophaga hutchinsonii] Length = 258 Score = 91.3 bits (225), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 49/126 (38%), Positives = 80/126 (63%), Gaps = 3/126 (2%) Query: 3 YTVKEVAVLSGTTVKTLHHYHKTGLLVPAEISEAGYRLYGMAELERLQQIMLYKELDFTL 62 Y+VK++A +SG +++TLHHY K GLL P+ +EA YR+YG EL RLQQI+ YKELDF+L Sbjct: 4 YSVKKLAQISGVSIRTLHHYDKIGLLKPSVRTEARYRMYGEPELIRLQQILFYKELDFSL 63 Query: 63 EQIGQLLKEEPDRLSI--LVXXXXXXXXXXXXIDMIIETLRKSVTSRERGEPMKDTEMFK 120 ++I ++ ++PD +I L I ++ T+ K++ + + D E++ Sbjct: 64 QKIAAIM-DDPDFNTIDALESHRILMQSRADRISQLLTTIDKTILKLKGKIMLTDKELYA 122 Query: 121 GLASEQ 126 GL++E+ Sbjct: 123 GLSTEK 128 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.135 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 293,184,425 Number of extensions: 9743592 Number of successful extensions: 24628 Number of sequences better than 1.0e-05: 86 Number of HSP's gapped: 24699 Number of HSP's successfully gapped: 86 Length of query: 251 Length of database: 757,237,578 Length adjustment: 123 Effective length of query: 128 Effective length of database: 423,280,401 Effective search space: 54179891328 Effective search space used: 54179891328 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)