BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0196.0003.p (186 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_658599.1| tetR, Bacterial regulatory proteins, tetR famil... 96 6e-19 ref|NP_977532.1| transcriptional regulator, TetR family, putativ... 95 8e-19 ref|NP_980994.1| transcriptional regulator, TetR family [Bacillu... 95 9e-19 ref|NP_834276.1| Transcriptional regulator, TetR family [Bacillu... 94 1e-18 ref|NP_465700.1| similar to transcriptional regulator (tetR fami... 86 3e-16 >ref|NP_658599.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_847017.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP28503.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 205 Score = 95.5 bits (236), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 63/190 (33%), Positives = 99/190 (52%), Gaps = 13/190 (6%) Query: 2 DRRIQKSRQAIIDAFMRLMSEKEFESITVNQIAEEANVNRGTVYLHFKDKYDLRDQHMEA 61 D R++++RQ I DAF+ L+ EK FE++TV IAE A VNR T Y H+ DKYDL D+ +E Sbjct: 8 DPRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEE 67 Query: 62 QINQLLHECMSEDN-------MVHLPSKTALLRTFEYLEQHASFYSLML--KSKGNTVFR 112 + +L E + N + L FE++ ++A+FY++ML K+ GN ++ Sbjct: 68 MLEKLT-EVIKPKNRNKEDFQLAFDSPHPNFLALFEHIAENANFYNVMLGDKAAGNYTYK 126 Query: 113 NQVETMFRQRLSEHLDSINLDGEL--NKDITVQFLISAAVGVLEWWIIRSMPYPASVMVE 170 LS + N D +L +DI + ++ A +G++ W+ R M Y M Sbjct: 127 MMKAIQTHLTLSLSISQPN-DEKLMVPRDILISYVTGAHLGMIMSWLKRGMIYTPHFMAM 185 Query: 171 QFWILLNQGV 180 Q L+ G Sbjct: 186 QLTRLIILGA 195 >ref|NP_977532.1| transcriptional regulator, TetR family, putative [Bacillus cereus ATCC 10987] gb|AAS40140.1| transcriptional regulator, TetR family, putative [Bacillus cereus ATCC 10987] Length = 181 Score = 94.7 bits (234), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 52/181 (28%), Positives = 100/181 (55%), Gaps = 4/181 (2%) Query: 1 MDRRIQKSRQAIIDAFMRLMSEKEFESITVNQIAEEANVNRGTVYLHFKDKYDLRDQHME 60 +DRRI KS+ AI AF+ ++ F+ ITV I E+AN+ R T YLH+ DKY+L D+ ++ Sbjct: 4 IDRRIIKSQNAIQSAFIEMLITDGFDEITVKNITEKANIGRKTFYLHYLDKYNLLDKIVD 63 Query: 61 AQINQLLHECMSEDNMVHLPSKTALLRTFEYLEQHASFYSLMLKSKGNTVFRNQVETMFR 120 ++QL C + N + + FEY ++H F++ + KS F+ ++ T Sbjct: 64 DHLDQLKEICYEKQNKGFIE---GTIIWFEYFKEHKPFFAALFKSNSTLSFQKKLLTFIM 120 Query: 121 QRLSEHLDS-INLDGELNKDITVQFLISAAVGVLEWWIIRSMPYPASVMVEQFWILLNQG 179 + + L++ +++ ++K I ++FL +A +G+LE +++ + + Q L+ + Sbjct: 121 GEIEKKLNTNTSINKNIDKHIILKFLGTAVMGILESYVLNEIDSDVEYVATQVGELMRRN 180 Query: 180 V 180 + Sbjct: 181 I 181 >ref|NP_980994.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS43602.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 205 Score = 94.7 bits (234), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 63/189 (33%), Positives = 100/189 (52%), Gaps = 11/189 (5%) Query: 2 DRRIQKSRQAIIDAFMRLMSEKEFESITVNQIAEEANVNRGTVYLHFKDKYDLRDQHMEA 61 D R++++RQ I DAF+ L+ EK FE++TV IAE A VNR T Y H+ DKYDL D+ +E Sbjct: 8 DPRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEE 67 Query: 62 QINQLLHECM-----SEDNMVHLPSK-TALLRTFEYLEQHASFYSLML--KSKGNTVFRN 113 + +L ED + S + L FE++ ++A+FY++ML K+ GN ++ Sbjct: 68 MLEKLTKVIKQKNRNKEDFQLTFDSPHPSFLALFEHIAENANFYNVMLGDKAAGNYTYKM 127 Query: 114 QVETMFRQRLSEHLDSINLDGEL--NKDITVQFLISAAVGVLEWWIIRSMPYPASVMVEQ 171 LS + N D +L +DI + ++ A +G++ W+ + M Y M Q Sbjct: 128 MKAIQTHLTLSLSISQPN-DEKLMVPRDILISYVTGAHLGMIMSWLKKGMIYTPHFMAMQ 186 Query: 172 FWILLNQGV 180 L+ G Sbjct: 187 LTRLIILGA 195 >ref|NP_834276.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP11477.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 205 Score = 94.4 bits (233), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 63/189 (33%), Positives = 99/189 (52%), Gaps = 11/189 (5%) Query: 2 DRRIQKSRQAIIDAFMRLMSEKEFESITVNQIAEEANVNRGTVYLHFKDKYDLRDQHMEA 61 D R++++RQ I DAF+ L+ EK FE++TV IAE A VNR T Y H+ DKYDL D+ +E Sbjct: 8 DPRVKRTRQLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEE 67 Query: 62 QINQLLHECMS-----EDNMVHLPSK-TALLRTFEYLEQHASFYSLML--KSKGNTVFRN 113 + +L ED + S + L FE++ ++ +FY++ML K+ GN ++ Sbjct: 68 MLEKLTEVIKPRNRNKEDFQLTFDSPHPSFLALFEHIAENTNFYNVMLGDKAAGNYTYKM 127 Query: 114 QVETMFRQRLSEHLDSINLDGEL--NKDITVQFLISAAVGVLEWWIIRSMPYPASVMVEQ 171 LS + N D +L +DI + ++ A +G++ W+ R M Y M Q Sbjct: 128 MKAIQTHLTLSLSISQPN-DEKLMVPRDILISYVTGAHLGMIMSWLKRGMIYTPHFMAMQ 186 Query: 172 FWILLNQGV 180 L+ G Sbjct: 187 LTRLIILGA 195 >ref|NP_465700.1| similar to transcriptional regulator (tetR family) [Listeria monocytogenes EGD-e] pir||AH1346 transcription regulator (tetR family) homolog lmo2176 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAD00254.1| lmo2176 [Listeria monocytogenes] Length = 187 Score = 86.3 bits (212), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 50/183 (27%), Positives = 94/183 (51%), Gaps = 8/183 (4%) Query: 1 MDRRIQKSRQAIIDAFMRLMSEKEFESITVNQIAEEANVNRGTVYLHFKDKYDLRDQHME 60 MDRR++K+++A A L+ +K F+ IT+ I EA+VNRGT Y H++DK +L D +E Sbjct: 1 MDRRVKKTKKAFNQALFTLLDQKPFQQITITDIVTEADVNRGTFYKHYRDKEELLDSIIE 60 Query: 61 AQINQLLHECMSEDNMVHLPS------KTALLRTFEYLEQHASFYSLMLKSKGNTVFRNQ 114 + L + +D +H ++++ F+++ H +FY ++KS F+NQ Sbjct: 61 EILMDL--KSAYQDPYLHTSHFSIQTLTPSMIKIFDHVYHHQAFYRQVIKSTIRPSFQNQ 118 Query: 115 VETMFRQRLSEHLDSINLDGELNKDITVQFLISAAVGVLEWWIIRSMPYPASVMVEQFWI 174 V + R+ + + + S E N + + A G++ +W + + M EQ Sbjct: 119 VCDVIRELILDDVASFPDSSEANLQLLATYQAHAIFGMIVFWAEEDFSHSPAYMSEQLLY 178 Query: 175 LLN 177 +++ Sbjct: 179 IIH 181 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.132 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 244,750,082 Number of extensions: 8918780 Number of successful extensions: 26391 Number of sequences better than 1.0e-05: 88 Number of HSP's gapped: 26399 Number of HSP's successfully gapped: 88 Length of query: 186 Length of database: 757,237,578 Length adjustment: 118 Effective length of query: 68 Effective length of database: 436,855,896 Effective search space: 29706200928 Effective search space used: 29706200928 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 122 (51.6 bits)