BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0193.0008.p (333 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00062576.1| COG0642: Signal transduction histidine kinase... 194 3e-48 ref|NP_831727.1| Two component system histidine kinase [Bacillus... 187 3e-46 ref|NP_978357.1| sensor histidine kinase [Bacillus cereus ATCC 1... 185 1e-45 ref|NP_466105.1| similar to two-component sensor histidine kinas... 182 8e-45 ref|NP_655820.1| HATPase_c, Histidine kinase-, DNA gyrase B-, ph... 178 2e-43 >ref|ZP_00062576.1| COG0642: Signal transduction histidine kinase [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] Length = 355 Score = 194 bits (492), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 98/271 (36%), Positives = 158/271 (58%), Gaps = 5/271 (1%) Query: 61 PIADLIKAAKEVSRGNFDIHLDESH---RVGEISDVAHHFNIMVQELRSIETLRNDFVVN 117 P++ L +A ++V++G+F ++L+ H + ++ V +FN+M++EL S ETL+NDF+ N Sbjct: 80 PVSQLNEATRQVAQGDFSVYLEPGHAREKYNDLDYVFENFNLMIEELGSTETLKNDFIAN 139 Query: 118 VSHEFKTPLAAIEGYATLLQDDSLSKEEHDEYTGMIIDSARQLSALSGNILKISKXXXXX 177 VSHEFK PLA I YA L++++ +E+ D YT +I+D +++ + N+LK+SK Sbjct: 140 VSHEFKAPLAVIRSYAEALKNET-DEEQRDMYTQIIVDETDKMATMVTNVLKLSKIENQA 198 Query: 178 XXXXXXXYXXXXXXXXXXXXXXSAWEPKQLNLNIDL-DELHYYGNEELMMQVWLNVLGNA 236 Y W ++L+I++ D++ + E+M VW N+L NA Sbjct: 199 LQPHIKKYNVSRQLVETLLNFEKIWASHNISLDINIPDDIEIAADPEMMELVWQNLLSNA 258 Query: 237 IKFTPEGGEISVSLRPDGPWISAVIADTGIGMTPKVRKHIFEKFYQGDPARSAEGNGLGL 296 KF P G++++ L+ + + D G GM IF+KFYQG+ + + +GNGLGL Sbjct: 259 FKFVPSDGQVTLRLQQNNEGTEITVRDNGEGMDHNTLNRIFDKFYQGETSHTNQGNGLGL 318 Query: 297 PLVARIISLSGGRIEVSSEPGVGSAFTIKLP 327 LV RI++L G I V S+ G GSAFT+ LP Sbjct: 319 SLVNRIVTLMQGSISVESKLGKGSAFTVWLP 349 >ref|NP_831727.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] gb|AAP08928.1| Two component system histidine kinase [Bacillus cereus ATCC 14579] Length = 348 Score = 187 bits (475), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 94/272 (34%), Positives = 160/272 (58%), Gaps = 3/272 (1%) Query: 60 APIADLIKAAKEVSRGNFDIHL-DESHRVGEISDVAHHFNIMVQELRSIETLRNDFVVNV 118 A I +I+ +++++G+F + + +E GEI + N M EL ++E +R +FV NV Sbjct: 73 AMIWTIIEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNTMEKMRQEFVSNV 132 Query: 119 SHEFKTPLAAIEGYATLLQDDSLSKEEHDEYTGMIIDSARQLSALSGNILKISKXXXXXX 178 SHE ++PL +I+G+A LQDD+LS+E+ Y +I +LS LS N+LK++ Sbjct: 133 SHEIQSPLTSIKGFARALQDDNLSEEKRKHYLTIIETETTRLSKLSQNLLKLTLLESEEY 192 Query: 179 XXXXXXYXXXXXXXXXXXXXXSAWEPKQLNLNIDLDELHYYGNEELMMQVWLNVLGNAIK 238 Y W K++ L +DL++++ ++E M QVW+N++ N+IK Sbjct: 193 TPERVSYRLDQQLKQIVLNSEPLWAEKEIELELDLEKVYVIADQESMSQVWINLIHNSIK 252 Query: 239 FTPEGGEISVSLRPDGPWISAVIADTGIGMTPKVRKHIFEKFYQGDPARSAE--GNGLGL 296 FTP GG I++ L+ + I D+GIG++ + ++HIFE+FY+ D +R+ G+GLGL Sbjct: 253 FTPSGGTITIQLKEHETVVEVRIRDSGIGISEEQKQHIFERFYKADSSRNRAYGGSGLGL 312 Query: 297 PLVARIISLSGGRIEVSSEPGVGSAFTIKLPG 328 +V +++ L G I+V SE G G+ F +++P Sbjct: 313 AIVKKVLDLHHGEIKVESEEGKGTEFIVRMPN 344 >ref|NP_978357.1| sensor histidine kinase [Bacillus cereus ATCC 10987] gb|AAS40965.1| sensor histidine kinase [Bacillus cereus ATCC 10987] Length = 351 Score = 185 bits (469), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 93/271 (34%), Positives = 160/271 (59%), Gaps = 3/271 (1%) Query: 60 APIADLIKAAKEVSRGNFDIHL-DESHRVGEISDVAHHFNIMVQELRSIETLRNDFVVNV 118 A I +I+ +++++G+F + + +E GEI + N M EL ++E +R +FV NV Sbjct: 76 AMIWTIIEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNAMEKMRQEFVSNV 135 Query: 119 SHEFKTPLAAIEGYATLLQDDSLSKEEHDEYTGMIIDSARQLSALSGNILKISKXXXXXX 178 SHE ++PL +I+G+A LQD++LS+E+ + Y +I +LS LS N+LK++ Sbjct: 136 SHEIQSPLTSIKGFARALQDNNLSEEKREHYLTIIETETTRLSKLSQNLLKLTLLESEEY 195 Query: 179 XXXXXXYXXXXXXXXXXXXXXSAWEPKQLNLNIDLDELHYYGNEELMMQVWLNVLGNAIK 238 Y W K++ L ++L+++H ++E M QVW+N++ N+IK Sbjct: 196 TPERATYRLDQQLKQIVLNSEPLWAEKEIELELNLEKVHITADQESMSQVWINLIHNSIK 255 Query: 239 FTPEGGEISVSLRPDGPWISAVIADTGIGMTPKVRKHIFEKFYQGDPARSAE--GNGLGL 296 FTP GG I++ L+ + I D+GIG++ + ++HIFE+FY+ D +R+ G+GLGL Sbjct: 256 FTPNGGTITIQLKEYEKVVEVRIRDSGIGISKEQKQHIFERFYKADSSRNRAYGGSGLGL 315 Query: 297 PLVARIISLSGGRIEVSSEPGVGSAFTIKLP 327 +V +++ L G I+V SE G G+ F + +P Sbjct: 316 AIVKKVLDLHQGEIKVESEEGKGTEFIVCIP 346 >ref|NP_466105.1| similar to two-component sensor histidine kinase [Listeria monocytogenes EGD-e] pir||AF1397 two-component sensor histidine kinase homolog lmo2582 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAD00660.1| lmo2582 [Listeria monocytogenes] Length = 459 Score = 182 bits (463), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 94/274 (34%), Positives = 152/274 (55%), Gaps = 3/274 (1%) Query: 56 RKILAPIADLIKAAKEVSRGNFDIHLDESHRVGEISDVAHHFNIMVQELRSIETLRNDFV 115 R I+ P+ L A K++ +GN+D+ E R EI +A F M EL E R +FV Sbjct: 185 RYIVNPVVKLTNATKKIRKGNYDVAF-EVRRKDEIGQLADSFTKMASELEKSEAARQEFV 243 Query: 116 VNVSHEFKTPLAAIEGYATLLQDDSLSKEEHDEYTGMIIDSARQLSALSGNILKISKXXX 175 NVSHE ++PL +++G+A LL +L+++E EY ++ + +LS+L+ +L ++ Sbjct: 244 ANVSHELQSPLTSMQGFARLLGSGTLTEKEQAEYLTVLSEETTRLSSLTKQLLTLASLDQ 303 Query: 176 XXXXXXXXXYXXXXXXXXXXXXXXSAWEPKQLNLNIDLDELHYYGNEELMMQVWLNVLGN 235 +W K+L +N+DL +++Y G+ EL+ QVW N+L N Sbjct: 304 ESELRKKEPVHLAKQWRQLIQMTEWSWREKELTINLDLADVNYTGDAELLYQVWSNLLTN 363 Query: 236 AIKFTPEGGEISVSLRPDGPWISAVIADTGIGMTPKVRKHIFEKFYQGDPARSAE--GNG 293 AIKFTP+GG I V L D + + D+G+G++ IF++FY+ + +R+ E +G Sbjct: 364 AIKFTPQGGNIQVRLYEDTTNVFVEVQDSGVGISKVDMTKIFDRFYKANESRTREEGSSG 423 Query: 294 LGLPLVARIISLSGGRIEVSSEPGVGSAFTIKLP 327 LGL + +II+L G + V S G+ FT+KLP Sbjct: 424 LGLSICQKIITLHHGEVTVQSSLEKGTTFTVKLP 457 >ref|NP_655820.1| HATPase_c, Histidine kinase-, DNA gyrase B-, phytochrome-like ATPase [Bacillus anthracis A2012] Length = 357 Score = 178 bits (451), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 92/272 (33%), Positives = 155/272 (56%), Gaps = 3/272 (1%) Query: 60 APIADLIKAAKEVSRGNFDIHL-DESHRVGEISDVAHHFNIMVQELRSIETLRNDFVVNV 118 A I +I+ +++++G+F + + +E GEI + N M EL ++E +R +FV NV Sbjct: 82 AMIWTIIEPIQKIAKGDFSVKIRNEEKYDGEIGVLVKSINDMTDELNAMEKMRQEFVSNV 141 Query: 119 SHEFKTPLAAIEGYATLLQDDSLSKEEHDEYTGMIIDSARQLSALSGNILKISKXXXXXX 178 SHE ++PL +I+G+A LQD +L +E+ Y +I +LS LS N+LK++ Sbjct: 142 SHEIQSPLTSIKGFARALQDTNLPEEKRKHYLTIIETETTRLSKLSQNLLKLTLLESEEY 201 Query: 179 XXXXXXYXXXXXXXXXXXXXXSAWEPKQLNLNIDLDELHYYGNEELMMQVWLNVLGNAIK 238 Y W K++ L++DL+++H ++E M QVW+N++ N+IK Sbjct: 202 TPERVTYRLDQQLKQIVLNSEPLWAEKEIELDLDLEKVHITADQESMSQVWINLIHNSIK 261 Query: 239 FTPEGGEISVSLRPDGPWISAVIADTGIGMTPKVRKHIFEKFYQGDPARSAE--GNGLGL 296 FTP G IS+ L+ + I DTG G++ + ++HIFE+FY+ D +R+ G+GLGL Sbjct: 262 FTPSSGTISIKLKEYETLVEVRIRDTGSGISEEQKQHIFERFYKADSSRNRAYGGSGLGL 321 Query: 297 PLVARIISLSGGRIEVSSEPGVGSAFTIKLPG 328 +V +++ L G I+V SE G G+ + +P Sbjct: 322 AIVKKVLDLHQGEIKVESEEGNGTECIVCIPN 353 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.138 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 436,469,192 Number of extensions: 16540521 Number of successful extensions: 58122 Number of sequences better than 1.0e-05: 3833 Number of HSP's gapped: 54096 Number of HSP's successfully gapped: 3880 Length of query: 333 Length of database: 757,237,578 Length adjustment: 126 Effective length of query: 207 Effective length of database: 415,135,104 Effective search space: 85932966528 Effective search space used: 85932966528 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 126 (53.1 bits)