BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0184.0001.p (2091 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gb|AAR87760.1| putative peptide synthetase/polyketide synthase [... 1337 0.0 gb|AAM33468.1| peptide synthetase [Aphanizomenon ovalisporum] 963 0.0 ref|NP_754362.1| Putative peptide/polyketide synthase [Escherich... 941 0.0 ref|ZP_00124542.1| COG1020: Non-ribosomal peptide synthetase mod... 909 0.0 emb|CAD70195.1| non-ribosomal peptide synthetase; type I polyket... 901 0.0 >gb|AAR87760.1| putative peptide synthetase/polyketide synthase [Bacillus cereus] Length = 2562 Score = 1337 bits (3459), Expect = 0.0, Method: Compositional matrix adjust. Identities = 748/1948 (38%), Positives = 1130/1948 (58%), Gaps = 90/1948 (4%) Query: 1 MQEGMLFHYLKEPGSSLYFEQVSLHIASRVDLSAFEAAWQHVVSSNEMLRAVFRWEGVKE 60 +QEG+L+HYLKEP LY E++ L + ++++ FE AW +V NEMLR +FRWE VK+ Sbjct: 21 VQEGILYHYLKEPEGKLYHEELRLCLTGKINIPKFEEAWNYVTRENEMLRTIFRWEKVKQ 80 Query: 61 PVQIILKERSQFLQIIDVSSQGIGERSEFITKVMEDDRNSPFDLTEGAFRVCLYQFAEAD 120 PVQ+ILKE + + + S G KV D + FDL F + L E + Sbjct: 81 PVQLILKEHTPNI----IYSDG---------KVSNDTES--FDLQTVPFSIELCHLNEGE 125 Query: 121 YHMIMSHHHILFDGWSTGIILNEFMESYQLFLNQQQPSAALKKRYKEFIGLTRNKDKAEQ 180 Y M++ HHHILFDGWS IIL EF++ Y+ + PS+ KK++KE+I + +DK++Q Sbjct: 126 YEMVLRHHHILFDGWSNSIILQEFIKVYRELIKGDVPSSINKKKFKEYILWQQKQDKSKQ 185 Query: 181 ERFWAGYLQEVHPVWLQDILPASPSGQQAEGK---KQLRLELPLFLYEEIKQEGKYSVSC 237 + FW YL E+ Q L S Q + K K++ E +G +++ Sbjct: 186 KLFWEQYLNELTE---QINLSNKNSNQLKKAKTYVKEIDKERSDRFRSFASNQG-VTLAT 241 Query: 238 YLYTAWALLQAFYTDSRDIVFGTTISGREEALHGWEETVGLFINTLPLRLRIDPEETFKG 297 YTAW LL Y +S D++FGTT+SGR +HG E VGLFINT PLR+ D T Sbjct: 242 LFYTAWGLLLQRYKNSEDVIFGTTVSGRSIPMHGLSEMVGLFINTPPLRVSADGRMTVSD 301 Query: 298 LLEKVFVSLNARKEYGSTPLRDIKRYSGMPFEKELFDTILVIENYPLQ-NNLN--SRNML 354 LL+++ + R EY +TP+ D+ FDTI+V+ENYPL L ++ Sbjct: 302 LLQRIQSDVQRRTEYETTPIVDLNVS---------FDTIMVVENYPLDIEKLKEIDESVR 352 Query: 355 IDSFSYREETNYPLSIFITLWNSIEIVVDYSSQMYSEAFIHEAAARYQLILSSLVQHPEA 414 I + E TNY L++ I ++SI++ + + ++ E+ I + +L S++ Sbjct: 353 ISGYEVNEMTNYDLTVSIECFDSIKLAMMWPEDVFDESIIIGITNHFIQLLDSMLLDEGQ 412 Query: 415 PVASADFLFPEEQRKLLLEFANTEVMVPADKTIHQLFEEQADREPDRIALHYAGQIYSYR 474 P+ + L E + K LL+ + T+HQL E QA++ P+R+AL + +Y Sbjct: 413 PIQTLKML-DEAEEKFLLQGGQNQSATFPHTTLHQLIEMQAEKHPERVALTFENSEMTYG 471 Query: 475 QLNEQANQLANFLTGKGIQPNQLVGICMDRRPELLIAMLGILKSGGAYVPIDPILPEERI 534 +LNE+A+++A L +G+ + V + +D ++I++LGILK+GGAYVPIDP P+ERI Sbjct: 472 ELNERADKVAFALLKEGVTLDSPVVVMLDYSFNMIISLLGILKAGGAYVPIDPDYPQERI 531 Query: 535 AAMVQDGQIEVIITVQKYTDALMGMNGKQPVRQTLLCMDQDALQGHYGLQDILRFPHEAG 594 ++QD VIIT + D K T+L +++ +QD R Sbjct: 532 DFILQDSGSNVIITSNLFED-------KVKFDSTMLFIEE---LNETPMQDFERVD---- 577 Query: 595 IHPSTPENLAYVIYTSGSTGAPKGVMVSHGNVVNFIFGMDKRIGFRPDDKVLALTTYSFD 654 P NLAYVIYTSG+TG PKGVM+ H NV+ + F +D L ++ FD Sbjct: 578 ---VAPNNLAYVIYTSGTTGRPKGVMIEHSNVIQLVMHQPNSFKFSSNDVWLLFHSFCFD 634 Query: 655 IFVXXXXXXXXXXXXXXXAPDWVQKDPDAILRLIEQESIDILQATPSRMRML--VDSSLA 712 + V A +D + +LI E + +L TPS + V + Sbjct: 635 MSVWEIFGSLTYGGRLVLATKETIRDTYKLAQLIADEGVTVLNQTPSAFYVFQQVAEEMP 694 Query: 713 GCLQQPGKILIGGEGFPEDLYQS-LRKITDQQIYNVYGPTETTVWSTV-----QELEDTL 766 + I GGE L QS ++ + I N+YG TETTV T +E+ L Sbjct: 695 KLAFKIRLITFGGEMLKPGLLQSWFKRSPNTVIVNMYGITETTVHVTYMEIGEKEMHSNL 754 Query: 767 S-IGKPIANTGIYILSKDKHLRPLGYPGELCISGKGVAQGYLNQPGLTSDKFITNPYHPG 825 S IG P+ Y+ K + P G GEL + G GVA+GYLN+P L S++FI NPY+P Sbjct: 755 SAIGVPLPTYSCYVFDKHMNPTPKGMQGELYVGGHGVARGYLNRPELNSERFIQNPYNPS 814 Query: 826 ERLYCTGDYAYWLPDGRLQFVGRNDGQVKXXXXXXXXXXXXXXXKSYPAVKDAVVIEVEE 885 ERLY +GD L +G ++++GR+D QVK + + VK+AVV+ + Sbjct: 815 ERLYRSGDLVRILENGEMEYIGRSDHQVKIRGYRIETGEIEHHLQQHADVKEAVVLSIAF 874 Query: 886 AGDAALAAYLVTGSGFVREDFQAFLKSKLPYYAVPANLYPIGEIPYTSNLKVDRKALAQM 945 + L AY++T + + + +L K+P Y +P + E+P T+N KV+R+AL + Sbjct: 875 GEEQELCAYILTDQDISQNELRYYLTDKIPSYMIPMYFVLLSEMPLTTNGKVNRRALPK- 933 Query: 946 KTARMVPSGKLVEPRS---KLENEVAEIWKKVLKLESVGIFNRFFDIGGDSVKVIHLCNE 1002 P+ KLV+P +LE VA++WK+VL +E VG+++ FFD+GG+S+K++ L + Sbjct: 934 ------PT-KLVQPNDLLDELETTVADVWKEVLGVEKVGLYDNFFDVGGNSLKMVRLFSR 986 Query: 1003 LKARLNMEIPVQTIFDYPTIHEFVSYCNETMTRTTGEARQQPAEPKAFQPPILDFQDTDV 1062 L+++ E+ + +F YPT+H+ SY R+ + +QP E K + +L DV Sbjct: 987 LRSKFEKELTMPMLFRYPTVHDQASYF-----RSDNDMDRQPKEVK--KENLLSMNKNDV 1039 Query: 1063 AIIGMAGRFPGAADKEQFWSNLVSGKEAIKFYTDEELKALGMDSELLNNPKYVRAKGKLD 1122 A++GMA R PGA++ +QFWSNL G E+I+ +TDEEL +G+ E++ P Y+++KG L+ Sbjct: 1040 AVVGMAVRMPGASNLKQFWSNLEQGIESIRTFTDEELSEMGIPKEVIQKPNYIKSKGYLE 1099 Query: 1123 DSDCFDADFFGYTVAEAKWMDPQIRLLHECAWHALEDAGYEPESYPGAIGLYIGSSYNIY 1182 D D FD +FF Y++ EA+ MDPQ+R+LHECAW ALE AG E S G+Y+G S N + Sbjct: 1100 DVDAFDNEFFDYSLKEAEMMDPQLRILHECAWEALEQAG-EVNSSHMNTGVYVGGSPNFH 1158 Query: 1183 WVPEKFSPSLYASDQYQIYNMNSNSF-ATLIAYRMNLRGPAITVQTACSTSLVAIDRAYK 1241 W+ S S + +Q +N F AT +AY++NL+GPAITVQTACSTSLVAI A+ Sbjct: 1159 WLRSIASESSNTLEDFQAMLLNEKDFFATRLAYKLNLKGPAITVQTACSTSLVAIQNAWA 1218 Query: 1242 DLLFGDCDIAVAGGAAVTLLDEMGYIHQEGMVLSKDGHCRAFEKKAXXXXXXXXXXXXXX 1301 DL+ G CDIA+AGG ++T + GY++++GM+ S DGHCRAF+K A Sbjct: 1219 DLIDGRCDIALAGGVSITYPTKTGYLYEDGMIFSPDGHCRAFDKDAQGTVGGNGAGIVVL 1278 Query: 1302 KRLKNALADGDHIYSIIKSTAVNNDGNRKAGYSAPSAEGQAAVIQKAIQRSGIGSEQIHY 1361 KRL++AL DG+ I+ +IK AVNNDG+ KAG++AP +GQAAVI+ A + +G+ E+I Y Sbjct: 1279 KRLEDALRDGNLIHGVIKGAAVNNDGSNKAGFTAPGVDGQAAVIKSAHEIAGVKPEEISY 1338 Query: 1362 IEAHGTGTVLGDPVEIEGLKRAFNTSKKNYCGLGSVKTNIGHLEAAAGIAGLMKTSMSLQ 1421 IE HGTGT LGDP+E+E LK AF + +GSVKTNIGHL+AAAG+ G +KT ++L+ Sbjct: 1339 IETHGTGTQLGDPIEVEALKLAFGKQEPGRVLIGSVKTNIGHLDAAAGVGGFIKTVLALK 1398 Query: 1422 QRMFPASLNCDEINARIVLEDSPFYVNTRLLDLRNEDNYPLRAGVSSFGQGGSNAHVILE 1481 + P SL+ + N I +PF VNT L+ + E RAGVSSFG GG+NAH++LE Sbjct: 1399 NKKIPPSLHYNNPNPSIDFGKNPFRVNTELIPWKEEVR---RAGVSSFGMGGTNAHIVLE 1455 Query: 1482 EAPQVDSGPAQRRFQIMTLSAKTELALNNLKGKVRESFRRSPGVHLADAAYTLKVGRKSF 1541 P ++ + ++T+SAKTE +L+ + + +P + L+D AYTL+ GR+ F Sbjct: 1456 SVPDNAKNFEKQSWNLLTVSAKTEESLDKATNDLLLYLKENPEISLSDTAYTLQKGRREF 1515 Query: 1542 AHRSAFLCTETKEAIDILTAKETAKRWEAVVSEQAPSVVFMFSGQGAEYVNMALDLYRHE 1601 +R+A + ++AI+ L +T E + ++ + F+FSGQG++Y+NM DLY +E Sbjct: 1516 PYRTAVVANGIEDAIEKLV--DTG--LEKTNAMESRPLAFLFSGQGSQYINMGRDLYENE 1571 Query: 1602 PVFRDKLSECLTILQEISGLRYQDFLFPDGR-EQQAERHIHRQSVSQPLHFALEYSLAWL 1660 PVFR+ + + L +L + ++ L+P E +A ++R S++QPL F +EY+LA L Sbjct: 1572 PVFREHVDQGLALLSNWLDIDMKNILYPTKETEDKATEQLNRTSMTQPLLFTIEYALAKL 1631 Query: 1661 LMNWQVEPLSMIGYSIGEYVAACLAGVFSLRDALFLTYHRGVLMEKLPEGLMITVPLQEA 1720 LMNW V P M G+SIGE+VAACLA V S DAL L RG LM +PEG M++V L Sbjct: 1632 LMNWGVYPRVMFGHSIGEFVAACLAEVMSYEDALHLVMIRGKLMNSVPEGAMLSVNLSVE 1691 Query: 1721 DLLQILPPVLSVAAVN-DESCIVSGSKDSIAAFEALLKSRKLISMRLQISHAGHSKMLDS 1779 +L + + +AAVN + ++SG+ SI E LL + + + RL SHA HS+M+D Sbjct: 1692 ELQTYITDDIDIAAVNSSQHSVISGTVLSINKIEELLLNHGVKTTRLFTSHAFHSRMMDE 1751 Query: 1780 MISEFRECVQRVTCNPPAVPFVSSLTGDVITPEEAASPEHWVRHLREPVRFAEGFKKLAP 1839 ++ F + V + + P +P++S++TG++IT +A SP +W +HLR V+F++G ++ Sbjct: 1752 VLDAFEQAVGNIKLSSPKIPYISNVTGEMITANQATSPSYWAQHLRSTVQFSKGLSEIFH 1811 Query: 1840 QENTLFIEIGPGRNLCTLVQRFMLPDRKQKLLDTIRVERKKAADDEYLLRTVAQLWVNGV 1899 +N + +EIGPG L T V + + + Q L+ +R K+ D E+L + + +LW+ G Sbjct: 1812 LKNVICLEIGPGNALSTFVLKHLNRSKDQLALNMLRHPLDKSNDLEHLCKQIGRLWMQGG 1871 Query: 1900 SVDWSRFYSGEQRRRVPLPGYPFEKKRY 1927 ++DW+ F + E +R + LP YPF KKR+ Sbjct: 1872 TIDWNTFNNSENKRLLDLPTYPFMKKRF 1899 >gb|AAM33468.1| peptide synthetase [Aphanizomenon ovalisporum] Length = 1869 Score = 963 bits (2490), Expect = 0.0, Method: Compositional matrix adjust. Identities = 593/1596 (37%), Positives = 877/1596 (54%), Gaps = 125/1596 (7%) Query: 426 EQRKLLLEFANTEVMVPADKTIHQLFEEQADREPDRIALHYAGQIYSYRQLNEQANQLAN 485 E ++LL+ T+ P D IH LFE+QA R PD IAL Q +YR+LN +AN LA Sbjct: 5 ESPQILLDGNGTQSEFP-DSCIHHLFEDQAARRPDAIALIEGEQSLTYRELNVRANHLAQ 63 Query: 486 FLTGKGIQPNQLVGICMDRRPELLIAMLGILKSGGAYVPIDPILPEERIAAMVQDGQIEV 545 L G Q + LV IC++R EL I +LGILK+G AYVP+D P +RI M++D + Sbjct: 64 HLLSLGCQSDDLVAICIERSAELFIGLLGILKAGCAYVPLDVGYPVDRIEYMLRDSDARI 123 Query: 546 IITVQKYTDALMGMNGKQPVRQTL--LCMDQDALQGHYGLQDILRFPHEAGIH------- 596 ++T TD + P Q + +DQ+ + + I + H + Sbjct: 124 LLT---STDVAKKLALTIPALQECQTVYLDQEIFEYDFHFLAIGKLLHNQYLRLLHFYFY 180 Query: 597 --------------------PSTPENLAYVIYTSGSTGAPKGVMVSHGNVVNFIFGMDKR 636 P NLAY IYTSGSTG PKG+++ H ++VN ++ + Sbjct: 181 TLIQQCRVFQANSVSQEIQTQVLPNNLAYCIYTSGSTGNPKGILMEHRSLVNMLWWHQQT 240 Query: 637 IGFRPDDKVLALTTYSFDIFVXXXXXXXXXXXXXXXAPDWVQKDPDAILRLIEQESIDIL 696 + L SFD P+ V+++P A+ I Q+ I+ L Sbjct: 241 RPSVQGVRTLQFCAVSFDFSCHEIFSTLCLGGILVLVPEAVRQNPFALAEFISQQKIEKL 300 Query: 697 QATPSRMRMLVD-------SSLAGCLQQPGKILIGGEGFP-----EDLYQSLRKITDQQI 744 + + L + +SLA C +++ GE +L+Q I + Sbjct: 301 FLPVTALLQLAEAVNGNKSTSLALC-----EVITTGEQMQITPAVANLFQKTGAI----L 351 Query: 745 YNVYGPTE------TTVWSTVQELEDTLSIGKPIANTGIYILSKDKHLRPLGYPGELCIS 798 +N YG TE T+ + + +G+P+ N +YIL + + P+G GELCI Sbjct: 352 HNHYGATEFQDATTHTLNGNPEGWPTLVPVGRPLHNVQVYILDEAQQPVPVGEEGELCIG 411 Query: 799 GKGVAQGYLNQPGLTSDKFITNPYHP---GERLYCTGDYAYWLPDGRLQFVGRNDGQVKX 855 G G+A+GY N P LT++KFI NP+ ++LY TGD A +LPDG ++ +GR D QVK Sbjct: 412 GIGLARGYHNLPDLTNEKFIPNPFGTNGNAKKLYRTGDLARYLPDGTIEHLGRIDHQVKI 471 Query: 856 XXXXXXXXXXXXXXKSYPAVKDAVVIEVEEAGDAALAAYLVTGS----GFVRED--FQAF 909 S+ AV++ V+ E AG L Y++ F + + + + Sbjct: 472 RGFRVELGEIESVLTSHQAVRECAVVAREIAGHTQLVGYILAKDTPNLSFDKLEPILRQY 531 Query: 910 LKSKLPYYAVPANLYPIGEIPYTSNLKVDRKALAQMKTARMVPSGKLVEPRSKLENEVAE 969 ++ LP Y +P I +P T + K+DR+AL K R S LV+PR++ E +AE Sbjct: 532 SEAVLPEYMIPTRFINISNMPLTPSGKLDRRALPDPKGDRPALSTPLVKPRTQTEKRLAE 591 Query: 970 IWKKVLKLESVGIFNRFFDIGGDSVKVIHLCNELKARLNMEIPVQTIFDYPTIHEFVSY- 1028 IW L ++ VGI + FFD+GG S+ + L N+ + ++F YPTI Y Sbjct: 592 IWGSYLAVDIVGIQDNFFDLGGTSLLLTQAHKFLCETFNINLSAVSLFQYPTIQTLAQYI 651 Query: 1029 -CNETMTRTTGEARQQPAEPKAFQPPILDFQDTDVAIIGMAGRFPGAADKEQFWSNLVSG 1087 C T +R + K D+AII +AGRFPGA EQFW NL +G Sbjct: 652 DCQGDTTSRDTASRHKKVRRKQ------SGDSNDIAIISVAGRFPGAETIEQFWHNLCNG 705 Query: 1088 KEAIKFYTDEELKALGMDSELLNNPKYVRAKGKLDDSDCFDADFFGYTVAEAKWMDPQIR 1147 E+I ++D+EL+ EL NNP YV+A L+ + FDA FFGY+ EA MDPQ R Sbjct: 706 VESITLFSDDELEQ--TLPELFNNPAYVKAGAVLEGVELFDATFFGYSPKEAAVMDPQQR 763 Query: 1148 LLHECAWHALEDAGYEPESYPGAIGLYIGSSYNIYWVPEKFS--------PSLYAS-DQY 1198 +L ECAW A E AGY PE+YP A+G+Y GSS + Y + S P + +Q+ Sbjct: 764 ILLECAWEAFERAGYNPETYPEAVGVYAGSSLSTYLLNNIGSALGIITEQPFIETDMEQF 823 Query: 1199 QIYNMNSNSF-ATLIAYRMNLRGPAITVQTACSTSLVAIDRAYKDLLFGDCDIAVAGGAA 1257 Q N S+ AT I++++NL+GP++ VQTACSTSLVA+ A + L+ G+C +A+AGG + Sbjct: 824 QAKIGNDRSYLATRISHKLNLKGPSVNVQTACSTSLVAVHMACQSLISGECQMALAGGIS 883 Query: 1258 VTLLDEMGYIHQEGMVLSKDGHCRAFEKKAXXXXXXXXXXXXXXKRLKNALADGDHIYSI 1317 V + + GY+++EGMV S+DGHCRAF+ KA KRL++AL D D+I ++ Sbjct: 884 VVVPHKGGYLYEEGMVRSQDGHCRAFDAKAQGTIFGNGGGLVLLKRLQDALDDNDNIMAV 943 Query: 1318 IKSTAVNNDGNRKAGYSAPSAEGQAAVIQKAIQRSGIGSEQIHYIEAHGTGTVLGDPVEI 1377 IK+TA+NNDG K GY+APS +GQA VI +AI + I + I Y+EAHGTGT LGDP+E+ Sbjct: 944 IKATAINNDGALKIGYTAPSVDGQADVISEAIAIADIDASTIGYVEAHGTGTQLGDPIEV 1003 Query: 1378 EGLKRAFNTSK-----KNYCGLGSVKTNIGHLEAAAGIAGLMKTSMSLQQRMFPASLNCD 1432 GL RAF S K C +GSVKTNIGHL+ AAGIAGL+K +++LQ P SL+ Sbjct: 1004 AGLARAFQRSTDSVLGKRQCAIGSVKTNIGHLDEAAGIAGLIKVALALQYGQIPPSLHYA 1063 Query: 1433 EINARIVLEDSPFYVNTRLLDLRNEDNYPLRAGVSSFGQGGSNAHVILEEA----PQVDS 1488 N RI + +PF+VNT L + + + YPLRAGVSSFG GG+N+H++LEE+ P + S Sbjct: 1064 NPNPRIDFDATPFFVNTELREW-SRNGYPLRAGVSSFGVGGTNSHIVLEESPVKQPTLFS 1122 Query: 1489 GPAQRRFQIMTLSAKTELALNNLKGKVRESFRRSPGVHLADAAYTLKVGRKSFAHRSAFL 1548 +R ++TLSA T+ AL+ L + + + L D +T GRK F HR A + Sbjct: 1123 SLPERSHHLLTLSAHTQEALHELVQRYIQHNETHLDIDLGDLCFTANTGRKHFEHRLAVV 1182 Query: 1549 CTETKEAIDILTAK-ETAKRWEAVVSEQA-PSVVFMFSGQGAEYVNMALDLYRHEPVFRD 1606 E+I L A+ ETA+ + + A P++ F+F+GQG++Y+NM LY E FR Sbjct: 1183 A----ESIPGLQAQLETAQTAISAQKKNAPPTIAFLFTGQGSQYINMGRTLYDTESTFRA 1238 Query: 1607 KLSECLTILQEISGLRYQDFLFPDGREQQAERHIHRQSVSQPLHFALEYSLAWLLMNWQV 1666 L C TILQ + +F + + + +QP FA+EY+L L +W + Sbjct: 1239 ALDRCETILQNLGIESILSVIFGSSEHGLS---LDDTAYTQPALFAIEYALYQLWKSWGI 1295 Query: 1667 EPLSMIGYSIGEYVAACLAGVFSLRDALFLTYHRGVLMEKLP-EGLMITVPLQEADLLQ- 1724 +P +IG+S GEYV+AC+AGVFSL D L L RG L++ LP +G M++V E + + Sbjct: 1296 QPSVVIGHSAGEYVSACVAGVFSLEDGLKLIAERGRLIQALPRDGSMVSVMASEKRIAEF 1355 Query: 1725 --ILP--PVLSVAAVND-ESCIVSGSKDSIAAFEALLKSRKLISMRLQISHAGHSKMLDS 1779 ILP +++AA+N +S ++SG + +I A +L++ + S +L +SHA HS ++++ Sbjct: 1356 DIILPYGGQVAIAAINGPQSVVISGQQQAIDAISTILETEGIKSKKLNVSHAFHSPLVEA 1415 Query: 1780 MISEFRECVQRVTCNPPAVPFVSSLTGDVITPEEA------ASPEHWVRHLREPVRFAEG 1833 M+ F + Q VT + P + +S++TG + + E + E+WVRH+R+PVRFA G Sbjct: 1416 MLDSFLQVAQEVTYSEPQIKLISNVTGTLASHESCPDELPITTAEYWVRHVRQPVRFAAG 1475 Query: 1834 FKKLAPQENTLFIEIGPGRNLCTLVQRFMLPDRKQKLLDTIRVERKKAADDEYLLRTVAQ 1893 + L Q +FIEIGP L + R LP+++ L ++ R K D + +L ++ Sbjct: 1476 MESLEGQGVNVFIEIGPKPVLLGM-GRDCLPEQEGLWLPSL---RPKQDDWQQVLSSLRD 1531 Query: 1894 LWVNGVSVDWSRFYSGEQRRRVPLPGYPFEKKRYWL 1929 L++ GV+VDWS F+ G RRRVPLP YP++++R+W+ Sbjct: 1532 LYLAGVTVDWSSFHQGYARRRVPLPTYPWQRERHWV 1567 >ref|NP_754362.1| Putative peptide/polyketide synthase [Escherichia coli CFT073] gb|AAN80929.1| Putative peptide/polyketide synthase [Escherichia coli CFT073] Length = 1875 Score = 941 bits (2433), Expect = 0.0, Method: Compositional matrix adjust. Identities = 622/1904 (32%), Positives = 955/1904 (50%), Gaps = 110/1904 (5%) Query: 2 QEGMLFHYLKEPGSSLYFEQVSLHIASRVDLSAFEAAWQHVVSSNEMLRAVFRWEGVKEP 61 Q+G LFH LK+ S Y E + + VD + F+ A + + +E R + WE + P Sbjct: 28 QQGFLFHSLKDKKRSNYHEHFTCIFSQHVDSAHFKWALETLFRKHECFRTDYNWEIDERP 87 Query: 62 VQIILKERSQFLQIIDVSSQGI----------------GERSEFITKVMEDDRNSPFDLT 105 Q++ + + ++D + I I ++++ D PF L Sbjct: 88 CQVVKTDVLPDIYVLDCEQEEIRFLLANDDIIIPVPQDDGIDAIIPQLLQADLKYPFSLK 147 Query: 106 EGAFRVCLYQFAEADYHMIMSHHHILFDGWSTGIILNEFMESY--QLFLNQQQPSAALKK 163 R L Q + + I+S+HHI+ DGWS + + + ++ Y + + SA + Sbjct: 148 TIPVRAYLIQ-STKESAFILSYHHIVMDGWSLSLFIKQLLQLYGAAVVSGVRDDSAIIPS 206 Query: 164 RYKEFIGLTRNKDKAEQERFWAGYLQEVHPVWLQDILPASPSGQQAEGKKQLRL----EL 219 K + + Q +WA YL+E P I+P S E + + + Sbjct: 207 SLKPLVDTLSARRHTFQHDYWAAYLREGTPTC---IVPLSQYHTDTEAENNSYVNQTNHV 263 Query: 220 PLFLYEEIKQEGKYSVSCY-------LYTAWALLQAFYTDSRDIVFGTTISGREEALHGW 272 + L ++ Q+ + S Y Y AW +L + + D++FG TISGR + G Sbjct: 264 EINLSPDVCQKIQTLCSDYRITPAVIFYVAWGILLQRWCYADDVLFGATISGRNIPIDGI 323 Query: 273 EETVGLFINTLPLRLRIDPEETFKGLLEKVFVSLNARKEYGSTPLRDIKRYSGMP-FEKE 331 EET+GLFINTLPLRLR D T L+++ +L A L I+R + Sbjct: 324 EETLGLFINTLPLRLR-DDGATLLQHLQRMHQTLIAHYSNEHDALASIQRLVHKEGHAGD 382 Query: 332 LFDTILVIENYPLQNNLNS--RNMLIDSFSYREETNYPLSIFITLWNSIEIVVDYSSQMY 389 LF+T++V+ENYP+ L S + I S E+T+YPL++ IT + Y+ Sbjct: 383 LFNTLVVLENYPVDMTLLSCASPVAIRHLSVHEQTHYPLTLTITQQKGFRFSIAYALNYL 442 Query: 390 SEAFIHEAAARYQLILSSLVQHPEAPVASADFLFPEEQRKLLLEFANTEVMVPAD----K 445 + +L LV +P+ P+A+ L P +Q ++L + E M D Sbjct: 443 TNNMAQALLMHLSYLLEQLVDNPQRPIAALVNLSPCQQAQVLQPY--LERMACRDWDSQS 500 Query: 446 TIHQLFEEQADREPDRIALHYAGQIYSYRQLNEQANQLANFLTGKGIQPNQLVGICMDRR 505 + + F + A P ++A+ +Y +L QA QLA +L +G+ VGI +RR Sbjct: 501 NVIEQFHQVAATSPAQVAVVDELCALTYSELAAQAEQLAAYLVQQGVMVGDTVGIISERR 560 Query: 506 PELLIAMLGILKSGGAYVPIDPILPEERIAAMVQDGQIEVIITVQKYTDALMGMNGKQPV 565 ++A++ I+ G AYVPI P P R+ ++ D + +++ K DAL V Sbjct: 561 VNTVVAIIAIMLIGAAYVPISPDYPVGRMQEIIDDSGLALLLVHGKPLDAL-------NV 613 Query: 566 RQTLLCMDQDALQGHYGLQDILRFPHEAGIHPSTPENLAYVIYTSGSTGAPKGVMVSHGN 625 Q+ LC + + + FP TP++ AYVIY+SGSTG PKG+ V+H Sbjct: 614 AQSDLCA--------FPVAPSVVFP------VITPDSRAYVIYSSGSTGKPKGIAVAHRG 659 Query: 626 VVNFIFGMDKRIGFRPDDKVLALTTYSFDIFVXXXXXXXXXXXXXXXAPDWVQKDPDAIL 685 ++ I G D + + L + FD+ V D + I Sbjct: 660 LLRLIQG-DSPLKVESGETTLLTCPFEFDVSVFEMWSTLLNHGKLVLLSKQALLDINHIR 718 Query: 686 RLIEQESIDILQATPSRMRMLV--DSSLAGCLQQPGKILIGGEGFPE-DLYQSLRKITDQ 742 R I E + T S V + G LQ I +GGE + ++K Sbjct: 719 RTIADEQVARAWFTSSLFNSYVAEGADFFGMLQH---ITVGGEAVSAWHVNDVMQKYPHL 775 Query: 743 QIYNVYGPTETTVWSTVQELEDT----LSIGKPIANTGIYILSKDKHLRPLGYPGELCIS 798 + N YGPTE T+++T + IG + T +YI HL P+G GEL Sbjct: 776 VVTNGYGPTENTIFTTAYRFNGLQPARVPIGYAVPGTSLYITDLHGHLLPIGATGELVAG 835 Query: 799 GKGVAQGYLNQPGLTSDKFITNPYHPGERLYCTGDYAYWLPDGRLQFVGRNDGQVKXXXX 858 G GVA GY N P L++ F+ +P+ PG +Y TGDYA L DG + GR DGQ+K Sbjct: 836 GVGVAIGYQNNPALSATVFVPDPFIPGGMMYKTGDYARLLDDGCVDCFGRKDGQIKINGQ 895 Query: 859 XXXXXXXXXXXKSYPAVKDAVVIEVEEAGDAALAAYLVTGSGFVREDFQAFLKSKLPYYA 918 + +AVV+ +AA + + + + L +LP +A Sbjct: 896 RIETGEIEQRLLECSGIIEAVVVPYRVRETLHIAAVVCVNDSYDEVEVRGQLADRLPPFA 955 Query: 919 VPANLYPIGEIPYTSNLKVDRKALAQMK-----TARMVPSGKLVEPRSKLENEVAEIWKK 973 +P +L + EI + + K D LAQ++ T S + E S +E+ + IW++ Sbjct: 956 IPESLVVVTEIAKSHSGKAD---LAQLRYLLPATQCNAVSTTISEVHSDMEHALHAIWQR 1012 Query: 974 VLKLESVGIFNRFFDIGGDSVKVIHLCNELKARLNMEIPVQTIFDYPTIHEFVSYCNETM 1033 VL + + FF +GG S+ I + ++K +L +EI + +F YPT+ + + + Sbjct: 1013 VLDRQDIDSNASFFALGGTSLDTIRVKGDIKRQLGLEIDITDLFKYPTLTALAHFLDTAV 1072 Query: 1034 TRTTGEARQQPAEPKAFQPPILDFQDTDVAIIGMAGRFPGAADKEQFWSNLVSGKEAIKF 1093 + A + + D VAI+GMAGRFPGAA+ W+ +V G+ + Sbjct: 1073 S-----------PEDAIPTRAVVYSDMPVAIVGMAGRFPGAANIAALWTLVVGGESGLTL 1121 Query: 1094 YTDEELKALGMDSELLNNPKYVRAKGKLDDSDCFDADFFGYTVAEAKWMDPQIRLLHECA 1153 ++DEEL+A G+ + L Y++ KG +DD + FDADFFGYT EA+ MDPQIRLLH+C Sbjct: 1122 FSDEELRAHGVTPDTLKQANYIKTKGIVDDHEWFDADFFGYTPNEAECMDPQIRLLHQCC 1181 Query: 1154 WHALEDAGYEPESYPGAIGLYIGSSYNIYWVPEKFSPSLYASDQYQIYNMNSNSFATLIA 1213 W LE AG +P ++ GAIG+Y G + +W+ + ++ Y+ +N +S LIA Sbjct: 1182 WQTLEHAGCDPATFTGAIGIYAGLLTSPHWLNAVMQDTTDSTALYKASILNIHSVTALIA 1241 Query: 1214 YRMNLRGPAITVQTACSTSLVAIDRAYKDLLFGDCDIAVAGGAAVTLLDEMGYIHQEGMV 1273 + +NL GPA+T+ TACSTS VAI +A L DCD A+AGG ++ + GY + EGM+ Sbjct: 1242 HALNLTGPAVTLDTACSTSAVAIHQACIALRNRDCDAALAGGVSIEMPAYRGYEYHEGMI 1301 Query: 1274 LSKDGHCRAFEKKAXXXXXXXXXXXXXXKRLKNALADGDHIYSIIKSTAVNNDGNRKAGY 1333 ++DG CR F+ +A KRL +ALAD D IY +IK +AVNNDGN K GY Sbjct: 1302 NARDGVCRPFDSQASGTVTGDGLGMLLLKRLDDALADRDCIYGVIKGSAVNNDGNNKIGY 1361 Query: 1334 SAPSAEGQAAVIQKAIQRSGIGSEQIHYIEAHGTGTVLGDPVEIEGLKRAFNTSKKNYCG 1393 +APS GQ+ VI+ +++R+G S+ I +EAHGTGTVLGDP+E+ L F + +C Sbjct: 1362 TAPSVIGQSTVIRTSLRRAGFDSDSIGLVEAHGTGTVLGDPIELRALNEVFGPTPVPFCV 1421 Query: 1394 LGSVKTNIGHLEAAAGIAGLMKTSMSLQQRMFPASLNCDEINARIVLEDSPFYVNTRLLD 1453 + ++K+NIGHL +AAG+AG++KT+++L ++ P + + ++N I L S YVN ++ Sbjct: 1422 VSALKSNIGHLNSAAGVAGVIKTTLALHHQVLPPTAHFRQLNPAIDLSRSALYVNQQVQP 1481 Query: 1454 LRNEDNYPLRAGVSSFGQGGSNAHVILEEAPQVD--SGPAQRRFQIMTLSAKTELALNNL 1511 + P RA VSSFG GG+NA + LE D S R ++ SAKT AL Sbjct: 1482 WPS--TRPRRALVSSFGIGGTNASIALEAHQHEDDPSATGVRDSYLLLFSAKTPAALELR 1539 Query: 1512 KGKVRESFRRSPGVHLADAAYTLKVGRKSFAHRSAFLCTETKEAIDILTAKETAKRWEAV 1571 E + GV L D AYTL+ GR +F HR A+L + + ID+ A T + E Sbjct: 1540 VASTLEYVKHGVGVRLPDVAYTLQTGRTAFDHRRAYLVSRGSK-IDLSCA--TILQAEIF 1596 Query: 1572 VSEQAPS-VVFMFSGQGAEYVNMALDLYRHEPVFRDKLSECLTILQEISGLRYQDFLFPD 1630 ++ + + FMF GQG++Y MA LY H+P+FR + C Q S + + LF D Sbjct: 1597 NGQRTTAEICFMFPGQGSQYHGMASALYAHQPMFRQHMDRCFAAFQRYSTVDLKALLFDD 1656 Query: 1631 GREQQAERHIHRQSVSQPLHFALEYSLAWLLMNWQVEPLSMIGYSIGEYVAACLAGVFSL 1690 + R I + +QP F +EYSLA L++ + P SMIG+S+GEYVAAC+AGVF+L Sbjct: 1657 ----EDTRDIDQTQFTQPALFCVEYSLARTLIDLGITPDSMIGHSLGEYVAACIAGVFTL 1712 Query: 1691 RDALFLTYHRGVLMEKLPEGLMITVPLQEADLLQILPPVLSVAAVNDES---CIVSGSKD 1747 DAL + RG LM+ + G M+ V L L L + + S C+V+G + Sbjct: 1713 EDALHVIEARGRLMQSMRPGSMMAVYLSREQLTPWLAAERGIELAANNSAHFCVVAGEQA 1772 Query: 1748 SIAAFEALLKSRKLISMRLQISHAGHSKMLDSMISEFRECVQRVTCNPPAVPFVSSLTGD 1807 +I+ L + RL+ SHA HS M+ M+ +F + + ++ + P F+S+++G Sbjct: 1773 AISRLSTRLVEGGIQHRRLKTSHAFHSAMMTPMLHDFAQLLGQIPMHAPHKRFISNVSGT 1832 Query: 1808 VITPEEAASPEHWVRHLREPVRFAEGFKKLAPQENTLFIEIGPG 1851 IT E+A SP++WV+ +R V F+EG +L Q TLFIE GPG Sbjct: 1833 WITEEQATSPDYWVQQVRNAVLFSEGAAQLLVQP-TLFIECGPG 1875 >ref|ZP_00124542.1| COG1020: Non-ribosomal peptide synthetase modules and related proteins [Pseudomonas syringae pv. syringae B728a] Length = 4190 Score = 909 bits (2349), Expect = 0.0, Method: Compositional matrix adjust. Identities = 633/1980 (31%), Positives = 1007/1980 (50%), Gaps = 122/1980 (6%) Query: 11 KEPGSSLYFEQVSLHIASRVDLSAFEAAWQHVVSSNEMLRAVFRWE--------GVKEPV 62 EPG++ ++ + ++D+ A E A ++ +E+LR F E GV + Sbjct: 1113 SEPGTAYNMPEIC-RLTGQLDIPALEGALNLLLERHEVLRTHFTRELETFVDTQGVTQKE 1171 Query: 63 QIILKERSQFLQIIDVSSQGIGERSEFITKVMEDDRNSPFDL-TEGAFRVCLYQFAEADY 121 +++ + ++ Q I E +T +E + ++PF L E R L Q A ++ Sbjct: 1172 PLVVTSHADSARV-PFRLQTIAR--EALTAALEREVHTPFVLDKELPIRALLLQTASDEH 1228 Query: 122 HMIMSHHHILFDGWSTGIILNEFMESYQLFLNQQQPS-AALKKRYKEFIGLTRNKDKA-- 178 + ++ HHI +DGWS+ ++ E Y+ ++ + + L+ +Y+++ RN+ + Sbjct: 1229 VLCLTLHHIAYDGWSSALLRQELAVFYRHLTQGERITLSPLEAQYQDYAAWQRNQLETGA 1288 Query: 179 --EQERFWAGYLQEVHPVWLQDILP--ASPSGQQAEGKKQLRLELPLFLYEEIKQ---EG 231 Q W LQ++ P +LP +SP + L LP + Q Sbjct: 1289 FTTQLDAWKASLQDLPPPL---VLPVRSSPREGNPLAGDYVALTLPGDCSARLDQLCLRL 1345 Query: 232 KYSVSCYLYTAWALLQAFYTDSRDIVFGTTISGREEALHGWEET--VGLFINTLPLRLRI 289 + + + ++ A+ALL YT DI+ G SGR+ E T +G F+N LPLRLR+ Sbjct: 1346 QCTPAMVMHAAFALLLHRYTGQDDILIGMPFSGRDHD----ESTNLIGFFVNLLPLRLRL 1401 Query: 290 DPEETFKGLLEKVFVSLNARKEYGSTP---LRDIKRYSGMPFEKELFDTILVIEN---YP 343 ++E+ +L A + S P L + +P + F LV+++ P Sbjct: 1402 RGPLRVAQVIEQSRQALLAAEANQSVPIDYLAQVLNPQRLPGKHPFFQAGLVVQSTTAVP 1461 Query: 344 LQ-NNLNSRNMLIDSFSYREETNYPLSIFITLWNSIEIVVDYSSQMYSEAFIHEAAARYQ 402 L ++ S + + S + + L + + V Y + ++ + I A +Q Sbjct: 1462 LSLPHVTSEEISLASTEVK--LDLMLELRAVKGEGVSGVFKYRTSLFERSVISGMAGHFQ 1519 Query: 403 LILSSLVQHPEAPVASADFLFPEEQRKLLLEFANTEVMVPADKTIHQLFEEQADREPDRI 462 +L +++ + E VA L EQ++L+ +F +T D + FE++ + P + Sbjct: 1520 CLLENMLANDEQTVAQVKMLSATEQQRLISQFNDTARDF-GDGDVVSRFEQRVRQTPQAM 1578 Query: 463 ALHYAGQIYSYRQLNEQANQLANFLTGKGIQPNQLVGICMDRRPELLIAMLGILKSGGAY 522 AL + ++Y +L+ AN +A+ L KG+Q + +G+ R P L+ MLGILK+ A+ Sbjct: 1579 ALQLQQRCWTYAELDRLANGIAHALIKKGVQAGEHIGLFTGRHPYLVAGMLGILKARCAF 1638 Query: 523 VPIDPILP-EERIAAMVQDGQIEVIITVQKYTDALMGMNGKQPVRQTLLCMDQDALQGHY 581 VP++P E + M++D + ++ + L + +TLL D + QG + Sbjct: 1639 VPLNPQDSMEGALGYMIKDAALHRVVGHRGLAHELAALG-----LETLLVDDFEGEQGEW 1693 Query: 582 GLQDILRFPHEAGIHPSTPENLAYVIYTSGSTGAPKGVMVSHGNVVNFIFGMDKRIGFRP 641 R P++LAY++YTSGSTG PKGVMVS N+ N + + Sbjct: 1694 SAPACQR----------EPQDLAYILYTSGSTGQPKGVMVSQCNIDNTASAFARTLELTG 1743 Query: 642 DDKVLALTTYSFD-IFVXXXXXXXXXXXXXXXAPDWVQKDPDAILRLIEQESIDILQATP 700 + L + FD + A + + PD ++ L+ ++ I LQ TP Sbjct: 1744 QSRQLQYFSPVFDGVCGEVFPVLISGATLVFAASEQLLPGPD-LVTLLREQRITHLQITP 1802 Query: 701 SRMRMLVDSSLAGCLQQPGKILIGGEGFPEDLYQSLRKITDQQIYNVYGPTETTVWSTVQ 760 + +R+L + LA + I+ GE P ++ Q+ ++ N YGPTETTV+++ + Sbjct: 1803 TALRLLPHAELA----ELKVIISAGEACPANVAQTW--AAGRRFLNGYGPTETTVYASAR 1856 Query: 761 ELEDTLS--IGKPIANTGIYILSKDKHLRPL--GYPGELCISGKGVAQGYLNQPGLTSDK 816 + D + +P+ N +Y+L D++L PL G PGEL I G GVAQGYLN T+ Sbjct: 1857 DYWDERGALVLRPLDNVRMYVL--DRYLNPLPCGVPGELYIGGSGVAQGYLNLDERTAQA 1914 Query: 817 FITNPY--HPGERLYCTGDYAYWLPDGRLQFVGRNDGQVKXXXXXXXXXXXXXXXKSYPA 874 F+ +PY P RLY TGD+ +G L +VGR D QVK + Sbjct: 1915 FLPDPYGVSPEARLYRTGDFVVRQFNGSLSYVGRIDNQVKIRGFRIELGDVETRLNAIAG 1974 Query: 875 VKDAVVI-EVEEAGDAALAAYLVTGSGFVREDFQAFLKSKLPYYAVPANLYPIGEIPYTS 933 ++ AVV+ + ++ G AL Y V + +A L LP ++VP L + E+P + Sbjct: 1975 LEQAVVVVKQDDQGHKALVGYYVGKPSVAQ--VRAELARVLPAHSVPERLVCLPELPLSR 2032 Query: 934 NLKVDRKAL-------AQMKTARMVPSG--KLVEPRSK-LENEVAEIWKKVLKLESVGIF 983 KVDRK+L AQ TA P+ V P K L N V IW++VL + + Sbjct: 2033 TGKVDRKSLENRVDQRAQEGTAVGTPATLPAAVRPAGKRLHNTVRTIWQEVLDCQEIDSD 2092 Query: 984 NRFFDIGGDSVKVIHLCNELKARLNMEIPVQTIFDYPTIHEFVSYCNETMTRTTGEARQQ 1043 + FFD+GG S++++ L L + + +F+YPT+ V++ E + E RQ Sbjct: 2093 DNFFDLGGHSLRIVETQKRLSELLQAPVAMTDLFEYPTLRGLVAHL-ERLHGPLPEVRQ- 2150 Query: 1044 PAEPKAFQPPILDFQDTDVAIIGMAGRFPGAADKEQFWSNLVSGKEAIKFYTDEELKALG 1103 + P +D + +A++GMAGRFPGAAD +FW N+ G E+ +++DE + A G Sbjct: 2151 ----ASEASPAIDPGNRTLAVVGMAGRFPGAADLSEFWQNITEGVESTLYFSDEVMLAHG 2206 Query: 1104 MDSELLNNPKYVRAKGKLDDSDCFDADFFGYTVAEAKWMDPQIRLLHECAWHALEDAGYE 1163 ++ +LL +V+ +L+D D FDA+FFG++ EA+ MDPQ R+ +CAW A+E AGY Sbjct: 2207 VNPDLLERADFVKCGNRLEDVDKFDAEFFGFSPREAQLMDPQQRIFLQCAWAAMEAAGYG 2266 Query: 1164 PESYPGAIGLYIGSSYNIYWVPEKFSPSLYASDQYQIYNM-----NSNSF-ATLIAYRMN 1217 +G++ +S + Y + + + Q+ N+ N F A+ +AY++N Sbjct: 2267 GALNDLRVGVFASASTSHYLLDHVYP----RRQELQLENIQWLLGNGRDFMASRVAYKLN 2322 Query: 1218 LRGPAITVQTACSTSLVAIDRAYKDLLFGDCDIAVAGGAAVTLLDEMGYIHQEGMVLSKD 1277 L GPAITV+TACS+SLVA+ A + LL G+ D+ + GGA+V GY G ++S D Sbjct: 2323 LAGPAITVETACSSSLVAVQMACESLLRGESDMVIVGGASVE-AQYYGYQAAPGSIISVD 2381 Query: 1278 GHCRAFEKKAXXXXXXXXXXXXXXKRLKNALADGDHIYSIIKSTAVNNDGNRKAGYSAPS 1337 GHCR F+ +A K A+ D DHI+++IK A+NNDG+ K Y+APS Sbjct: 2382 GHCRPFDAQASGTTGGSGCAVLVLKLADRAIEDRDHIHALIKGGAINNDGSSKVSYTAPS 2441 Query: 1338 AEGQAAVIQKAIQRSGIGSEQIHYIEAHGTGTVLGDPVEIEGLKRAFNTS----KKNYCG 1393 GQA V+ A+ + I ++ I Y+EAHGTGT LGDPVE+ L +A+ ++ +C Sbjct: 2442 VHGQAQVVSAALDAANISADSIGYVEAHGTGTRLGDPVEVRALTQAYTSALPHFTPGFCA 2501 Query: 1394 LGSVKTNIGHLEAAAGIAGLMKTSMSLQQRMFPASLNCDEINARIVLEDSPFYVNTRLLD 1453 LGS+K+NIGHL+AA+GIAGL+K +++Q + PASLN N I DSPFYVNT Sbjct: 2502 LGSLKSNIGHLDAASGIAGLVKAILAVQHNVLPASLNFTRANPEIDFSDSPFYVNTTSRP 2561 Query: 1454 LRNEDNYPLRAGVSSFGQGGSNAHVILEEAPQVDSGPA--QRRFQIMTLSAKTELALNNL 1511 + P RAGVSSFG GG+NAHVI+EE PQ P R+ I+ SA++ AL++ Sbjct: 2562 WPAAAS-PRRAGVSSFGIGGTNAHVIVEEPPQPSVRPHDDSERWYILPFSARSAAALDHQ 2620 Query: 1512 KGKVRESFRRSPGVHLADAAYTLKVGRKSFAHRSAFLCTETKEAIDILTAKETAKRWEAV 1571 + ++ ++P L D A+TL GR FA R + + A+ L A + E Sbjct: 2621 RRQLITCL-QNPAADLRDIAFTLGEGRTRFAFRDSVVSQSIAGALHALQAPSSTALME-- 2677 Query: 1572 VSEQAPSVVFMFSGQGAEYVNMALDLYRHEPVFRDKLSECLTILQEISGLRYQDFLFPDG 1631 Q +VFMFSGQG++Y M LY E VFR + C ILQ G+ L+P Sbjct: 2678 -RRQDRPIVFMFSGQGSQYAGMFKGLYDSEAVFRQTVDRCAVILQRY-GVDILACLYPPA 2735 Query: 1632 REQQAERHIHRQSVSQPLHFALEYSLAWLLMNWQVEPLSMIGYSIGEYVAACLAGVFSLR 1691 + + + R ++QP F +EY+ A LL + + P ++IG+S+GE VAAC AGV+S+ Sbjct: 2736 GSKTGDA-LSRTEIAQPALFVVEYACALLLQSRGIHPQALIGHSLGELVAACFAGVYSVE 2794 Query: 1692 DALFLTYHRGVLMEKLPEGLMITVPLQEADLLQILPPVLSVAAVNDE-SCIVSGSKDSIA 1750 D+L L RG LM++ G M+ V L EAD + L P + +AAVN C+++G ++IA Sbjct: 2795 DSLKLVVERGRLMQRQAPGAMLAVGLSEADCARFLEPGVELAAVNGPLQCVLAGDFEAIA 2854 Query: 1751 AFEALLKSRKLISMRLQISHAGHSKMLDSMISEFRECVQRVTCNPPAVPFVSSLTGDVIT 1810 E L L+ L SHA HS+M+ + V + PP + VS+ G + Sbjct: 2855 RVERQLAEEGLVGRVLDTSHAFHSRMMAPAAHALKAVVNGFSVQPPTIALVSNHNGGWFS 2914 Query: 1811 PEEAASPEHWVRHLREPVRFAEGFKKLAPQ-ENTLFIEIGPGRNLCTLVQRFMLPDRKQK 1869 + ++ ++W HL E VRF++G LA + E +F+E+GPGR L + ++ + P Sbjct: 2915 IDSSSQSDYWASHLLETVRFSDGIGLLADELEEPIFLEVGPGRALQSALKSYAEP---LC 2971 Query: 1870 LLDTIRVERKKAADDEYLLRTVAQLWVNGVSVDWSRFYSGEQRRRVPLPGYPFEKKRYWL 1929 +L R R +D+ L + +A LW G W++ RVPLP YPF + +W+ Sbjct: 2972 VLGCTRHARDSRSDEAALAQGIASLWRQGARFGWAQATGCTDGARVPLPTYPFARDSHWI 3031 Score = 324 bits (831), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 280/1066 (26%), Positives = 490/1066 (45%), Gaps = 84/1066 (7%) Query: 2 QEGMLFHYLKEPGSSLYFEQVSLHIASRVDLSAFEAAWQHVVSSNEMLRAVFRWEGVKEP 61 Q+ + F + E S+ Y +L I +D +A E A V LR +R+ + Sbjct: 36 QKSLWFMHQMEDASATYNVPFALRIDGALDRAALERAVDSVYQRQSALR--YRFPCIDGQ 93 Query: 62 VQIILKERSQFLQIIDVSSQGIGERSEFITKVME-DDRNSPFDLT-EGAFRVCLYQFAEA 119 I L + ++ +D+ ++ SE K E + FDL E R L A Sbjct: 94 PVIRLVDEQLLIRKVDLRAE---PDSEAALKAFEQSEARYVFDLEHEALLRATLLHCATD 150 Query: 120 DYHMIMSHHHILFDGWSTGIILNEFMESYQLFLNQQQPSA-ALKKRYKEFIGLT-RNKDK 177 ++ ++++ HHI+FDGWS I L+E +Y + + +A L + +++ L+ N ++ Sbjct: 151 EHVLLINVHHIVFDGWSMQIFLSEVASAYSALVRGSEVNAEPLNFDFGDYLSLSPSNAER 210 Query: 178 AEQERFWAGYLQEVHPVWLQDILPASPSGQQAEGKKQLRLELPLFLYEEIKQEGK-YSVS 236 A W L PV + P+ Q+ G++ ++P + + +K + V+ Sbjct: 211 APDIDHWQRRLAGAPPVLPLPLDNKRPAVQRYAGQR-CHFQVPEAVSDALKNLARECRVT 269 Query: 237 CYL--YTAWALLQAFYTDSRDIVFGTTISGREEALHGWEETVGLFINTLPLRLRIDPEET 294 Y+ A+++L YT D+V G+ +S R+ + E +G F+NTLP R+ + Sbjct: 270 PYMVGLAAFSVLLYRYTQEADLVIGSPMSNRQSS--DLEGVIGFFVNTLPNRIDASGSPS 327 Query: 295 FKGLLEKVFVSLNARKEYGSTPLRDI-------KRYSGMPFEKELFDTILVIENYPLQ-N 346 F LL++V S+ E+ P I + S P + LFD + E++ ++ Sbjct: 328 FVELLKRVRASVLDTFEHAHVPFDQIVEAIQPPRSLSHAPVFQVLFD--MANEDFSVELE 385 Query: 347 NLNSRNMLIDSFSYREETNYPLSIFITLW-NSIEIVVDYSSQMYSEAFIHEAAARYQLIL 405 NL +R +DS + + Y LS+ + L + ++Y + + E + +I+ Sbjct: 386 NLRTRVYTLDSCTAK----YDLSLTLALTARGMSGAIEYDTALLDERAVQGMIDSLLIIM 441 Query: 406 SSLVQHPEAPVASADFLFPEE-QRKLLLEFANTEVMVPADKTIHQLFEEQADREPDRIAL 464 + ++P+ + L E ++ L L HQ F+ A + + AL Sbjct: 442 EQVSRNPDGAIDDFSLLSCEAVEQALRLANHQPAAPQAPFAPFHQWFKRSAAQWGEADAL 501 Query: 465 HYAGQIYSYRQLNEQANQLANFLTGKGIQPNQLVGICMDRRPELLIAMLGILKSGGAYVP 524 Y + YSY QL+ +A LA L G++ V + PE++IA+L + + GG YVP Sbjct: 502 VYENRRYSYAQLDAEARVLAGHLHAAGVRRGDRVAVVQRYGPEVIIALLAVHQVGGIYVP 561 Query: 525 IDPILPEERIAAMVQDGQIEVIITVQKYTDALMGMNGKQPVRQTLLCMDQDALQGHYGLQ 584 + + + R A +++D + +++T+ + L G C+ QD L G Sbjct: 562 L--AIDDARHADLLKDIEPRLVLTLSACQEQLRGYP----------CLVQDDLPQATGTL 609 Query: 585 DILRFPHEAGIHPSTPENLAYVIYTSGSTGAPKGVMVSHGNVVNFIFGMDKRIG-FRPD- 642 F + PE++AY+I+TSGSTG PKGV VSHG+ V+ + +++ G P Sbjct: 610 HENEFEGRN----TQPEDIAYIIFTSGSTGRPKGVSVSHGSWVSLLQALEQTYGQTEPGV 665 Query: 643 DKVLALTTYSFDIFVXXXXXXXXXXXXXXXAPDWVQKDPDAILRLIEQESIDILQATPSR 702 +L + ++FD+F+ P DP+ + LI E + +L+ P+ Sbjct: 666 TGILQMANFTFDVFMSDVVRALAVGARLIMCPRQSLADPEQLYELITAERVTLLEFVPAV 725 Query: 703 MRMLVDSSLAGCLQQPGKIL-------IGGEGFPEDLYQSLRKITDQQ--IYNVYGPTET 753 +R ++ L++ G+ L G + + Y+ ++ + Q + +VYG TE Sbjct: 726 LRQMIRY-----LEETGRRLDTLRTLTCGADVWFVHEYRKMQTLCGPQTRVVSVYGVTEA 780 Query: 754 TVWSTVQEL-------EDTLSIGKPIANTGIYILSKDKHLRPLGYPGELCISGKGVAQGY 806 T S E E +L IG P+ NT +Y++ +L P PGEL I G VA GY Sbjct: 781 TCESATFEPDAGWYDPERSLPIGGPLPNTSLYLVDATLNLVPRTVPGELLIGGGAVASGY 840 Query: 807 LNQPGLTSDKFITNPYH------PG---ERLYCTGDYAYWLPDGRLQFVGRNDGQVKXXX 857 +N+P L F+T + PG +R Y TGD + DG ++F+GR+D QVK Sbjct: 841 MNRPELNEKSFLTGSFSASGRFLPGVGEQRFYRTGDLCRHMRDGTIEFLGRSDNQVKIRG 900 Query: 858 XXXXXXXXXXXXKSYPAVKDAVVIEVEEAG-DAALAAYLVTGSGFVREDFQAFLKSKLPY 916 +P V + V+ + G +A L Y+ T + + A+L +LP Sbjct: 901 FRIELGEVESVLADHPDVNECAVVTRQSPGAEAELIGYVQTRA--TAQQLNAYLGERLPG 958 Query: 917 YAVPANLYPIGEIPYTSNLKVDRKALAQMKTARMVPSGKLVEPRSKLENEVAEIWKKVLK 976 + VP L + +P T+N K+DRK+L + + S PR+ LE ++ E W+ +L Sbjct: 959 HMVPRLLVVLAALPLTANGKIDRKSLPEPDWTQ--DSRAYAAPRNSLEEQLVEDWQHLLN 1016 Query: 977 LESVGIFNRFFDIGGDSVKVIHLCNELKARLNMEIPVQTIFDYPTI 1022 + VGI + FF+ GG S+ V + ++K R + + + +F+ PT+ Sbjct: 1017 VPRVGIDDNFFESGGHSLLVTQVIAQIKKRFGVALSIANLFEGPTV 1062 >emb|CAD70195.1| non-ribosomal peptide synthetase; type I polyketide [Pseudomonas syringae] Length = 4190 Score = 901 bits (2328), Expect = 0.0, Method: Compositional matrix adjust. Identities = 633/1980 (31%), Positives = 1008/1980 (50%), Gaps = 122/1980 (6%) Query: 11 KEPGSSLYFEQVSLHIASRVDLSAFEAAWQHVVSSNEMLRAVFRWE--------GVKEPV 62 EPG++ ++ + ++D+ A E A ++ +E+LR F E GV + Sbjct: 1113 SEPGTAYNMPEIC-RLTGQLDIPALEGALNLLLERHEVLRTHFTRELETFVDTQGVTQKE 1171 Query: 63 QIILKERSQFLQIIDVSSQGIGERSEFITKVMEDDRNSPFDL-TEGAFRVCLYQFAEADY 121 +++ + ++ Q I E +T +E + ++PF L E R L Q A ++ Sbjct: 1172 PLVVTSHADSARV-PFRLQTIAR--EALTAALEVEVHTPFVLDKELPIRALLLQTASDEH 1228 Query: 122 HMIMSHHHILFDGWSTGIILNEFMESYQLFLNQQQPS-AALKKRYKEFIGLTRNKDKA-- 178 + ++ HHI +DGWS+ ++ E Y+ ++ + + L+ +Y+++ RN+ + Sbjct: 1229 VLCLTLHHIAYDGWSSALLRQELAVFYRHLTQGERITLSPLEAQYQDYAAWQRNQLETGA 1288 Query: 179 --EQERFWAGYLQEVHPVWLQDILP--ASPSGQQAEGKKQLRLELPLFLYEEIKQ---EG 231 Q W LQ++ P +LP +SP + L LP + Q Sbjct: 1289 FTTQIDAWKASLQDLPPPL---VLPVRSSPREGNPLAGDYVALTLPGDCSARLDQLCLRL 1345 Query: 232 KYSVSCYLYTAWALLQAFYTDSRDIVFGTTISGREEALHGWEET--VGLFINTLPLRLRI 289 + + + ++ A+ALL YT DI+ G SGR+ E T +G F+N LPLRLR+ Sbjct: 1346 QCTPAMVMHAAFALLLHRYTGQDDILIGMPFSGRDHD----ESTNLIGFFVNLLPLRLRL 1401 Query: 290 DPEETFKGLLEKVFVSLNARKEYGSTP---LRDIKRYSGMPFEKELFDTILVIEN---YP 343 ++E+ +L A + S P L + +P + F LV+++ P Sbjct: 1402 RGPLRVAQVIEQSRQALLAAEANQSVPIDYLAQVLNPQRLPGKHPFFQAGLVVQSTTAVP 1461 Query: 344 LQ-NNLNSRNMLIDSFSYREETNYPLSIFITLWNSIEIVVDYSSQMYSEAFIHEAAARYQ 402 L ++ S + + S + + L + + V Y + ++ + I A +Q Sbjct: 1462 LSLPHVKSEEISLASTEVK--LDLMLELRAVKGEGVSGVFKYRTSLFERSVISGMAGHFQ 1519 Query: 403 LILSSLVQHPEAPVASADFLFPEEQRKLLLEFANTEVMVPADKTIHQLFEEQADREPDRI 462 +L +++ + E VA L EQ++L+ +F +T D + FE++ + P I Sbjct: 1520 CLLENMLANDEQTVAQVKMLSATEQQRLISQFNDTARDF-GDGDVVSRFEQRVRQTPQAI 1578 Query: 463 ALHYAGQIYSYRQLNEQANQLANFLTGKGIQPNQLVGICMDRRPELLIAMLGILKSGGAY 522 AL + ++Y +L+ AN +A+ L KG+Q + +G+ R P L+ MLGILK+ A+ Sbjct: 1579 ALQLQQRCWTYAELDRLANGIAHALIKKGVQAGEHIGLFTGRHPYLVAGMLGILKARCAF 1638 Query: 523 VPIDPILP-EERIAAMVQDGQIEVIITVQKYTDALMGMNGKQPVRQTLLCMDQDALQGHY 581 VP++P E + M++D + ++ + L + +TLL D + Q + Sbjct: 1639 VPLNPQDSMEGALGYMIKDAALHRVVGHRGLAHELAALG-----LETLLVDDFEGDQREW 1693 Query: 582 GLQDILRFPHEAGIHPSTPENLAYVIYTSGSTGAPKGVMVSHGNVVNFIFGMDKRIGFRP 641 R P++LAY++YTSGSTG PKGVMVS N+ N + + Sbjct: 1694 SAPACQR----------EPQDLAYILYTSGSTGQPKGVMVSQRNIDNTANAFARTLELTG 1743 Query: 642 DDKVLALTTYSFD-IFVXXXXXXXXXXXXXXXAPDWVQKDPDAILRLIEQESIDILQATP 700 + L + FD + A + + PD ++ L+ ++ I LQ TP Sbjct: 1744 QSRQLQYFSPVFDGVCGEVFPVLISGATLVFAASEQLLPGPD-LVTLLREQRITHLQITP 1802 Query: 701 SRMRMLVDSSLAGCLQQPGKILIGGEGFPEDLYQSLRKITDQQIYNVYGPTETTVWSTVQ 760 + +R+L + LA + I+ GE P ++ Q+ ++ N YGPTETTV+++ + Sbjct: 1803 TALRLLPHAELA----ELKVIISAGEACPANVAQTW--AAGRRFLNGYGPTETTVYASAR 1856 Query: 761 ELEDTLS--IGKPIANTGIYILSKDKHLRPL--GYPGELCISGKGVAQGYLNQPGLTSDK 816 + D + +P+ N +Y+L D++L PL G PGEL I G GVAQGYLN T+ Sbjct: 1857 DYWDERGALVLRPLDNVRMYVL--DRYLNPLPCGVPGELYIGGSGVAQGYLNLDERTAQA 1914 Query: 817 FITNPY--HPGERLYCTGDYAYWLPDGRLQFVGRNDGQVKXXXXXXXXXXXXXXXKSYPA 874 F+ +PY P RLY TGD+ +G L +VGR D QVK + Sbjct: 1915 FLPDPYGVSPEARLYRTGDFVVRQFNGSLSYVGRIDNQVKIRGFRIELGDVETRLNAIAG 1974 Query: 875 VKDAVVI-EVEEAGDAALAAYLVTGSGFVREDFQAFLKSKLPYYAVPANLYPIGEIPYTS 933 ++ AVV+ + ++ G AL Y V G+ V + +A L LP ++VP L + E+P + Sbjct: 1975 LEQAVVVVKQDDQGHKALVGYYV-GTPSVAQ-VRAELARVLPAHSVPERLVCLPELPLSR 2032 Query: 934 NLKVDRKAL-------AQMKTARMVPSG--KLVEPRSK-LENEVAEIWKKVLKLESVGIF 983 KVDRK+L AQ TA P+ V P K L N V IW++VL + + Sbjct: 2033 TGKVDRKSLENRVDQRAQEGTAVGTPATLPAAVRPAGKRLHNTVRTIWQEVLDCQEIDSD 2092 Query: 984 NRFFDIGGDSVKVIHLCNELKARLNMEIPVQTIFDYPTIHEFVSYCNETMTRTTGEARQQ 1043 + FFD+GG S++++ L L + + +F+YPT+ V++ + R G + Sbjct: 2093 DNFFDLGGHSLRIVETQKRLSELLQAPVAMTDLFEYPTLRGLVAH----LERLHGPLPEV 2148 Query: 1044 PAEPKAFQPPILDFQDTDVAIIGMAGRFPGAADKEQFWSNLVSGKEAIKFYTDEELKALG 1103 +A P +D + +A++GMAGRFPGAAD +FW N+ G E+ +++DE + A G Sbjct: 2149 GQASEA--SPAIDPGNRTLAVVGMAGRFPGAADLSEFWQNITEGVESTLYFSDEVMLAHG 2206 Query: 1104 MDSELLNNPKYVRAKGKLDDSDCFDADFFGYTVAEAKWMDPQIRLLHECAWHALEDAGYE 1163 + +LL +V+ +L+D D FDA+FFG++ EA+ MDPQ R+ +CAW A+E AGY Sbjct: 2207 VYPDLLERADFVKCGNRLEDVDKFDAEFFGFSPREAQLMDPQQRIFLQCAWAAMEAAGYG 2266 Query: 1164 PESYPGAIGLYIGSSYNIYWVPEKFSPSLYASDQYQIYNM-----NSNSF-ATLIAYRMN 1217 +G++ +S + Y + + + Q+ N+ N F A+ +AY++N Sbjct: 2267 GALNDLRVGVFASASTSHYLLDHVYP----RRQELQLENIQWLLGNGRDFMASRVAYKLN 2322 Query: 1218 LRGPAITVQTACSTSLVAIDRAYKDLLFGDCDIAVAGGAAVTLLDEMGYIHQEGMVLSKD 1277 L GPAITV+TACS+SLVA+ A + LL G+ D+ + GGA+V GY G ++S D Sbjct: 2323 LAGPAITVETACSSSLVAVQMACESLLRGESDMVIVGGASVE-AQYYGYQAAPGSIISVD 2381 Query: 1278 GHCRAFEKKAXXXXXXXXXXXXXXKRLKNALADGDHIYSIIKSTAVNNDGNRKAGYSAPS 1337 GHCR F+ +A K A+ D DHI+++IK A+NNDG+ K Y+APS Sbjct: 2382 GHCRPFDAQASGTTGGSGCAVLVLKLADRAIEDRDHIHALIKGGAINNDGSSKVSYTAPS 2441 Query: 1338 AEGQAAVIQKAIQRSGIGSEQIHYIEAHGTGTVLGDPVEIEGLKRAFNTS----KKNYCG 1393 GQA V+ A+ + I ++ I Y+EAHGTGT LGDPVE+ L +A+ ++ +C Sbjct: 2442 VHGQAQVVSAALDAANISADSIGYVEAHGTGTRLGDPVEVRALTQAYTSALPHFTPGFCA 2501 Query: 1394 LGSVKTNIGHLEAAAGIAGLMKTSMSLQQRMFPASLNCDEINARIVLEDSPFYVNTRLLD 1453 LGS+K+NIGHL+AA+GIAGL+K +++Q + PASLN N I DSPFYVNT Sbjct: 2502 LGSLKSNIGHLDAASGIAGLVKAILAVQHNVLPASLNFTRANPEIDFSDSPFYVNTTSRP 2561 Query: 1454 LRNEDNYPLRAGVSSFGQGGSNAHVILEEAPQVDSGPA--QRRFQIMTLSAKTELALNNL 1511 + P RAGVSSFG GG+NAHVI+EE PQ P R+ I+ SA++ AL++ Sbjct: 2562 WPAAAS-PRRAGVSSFGIGGTNAHVIVEEPPQPSVRPHDDSERWYILPFSARSAAALDHQ 2620 Query: 1512 KGKVRESFRRSPGVHLADAAYTLKVGRKSFAHRSAFLCTETKEAIDILTAKETAKRWEAV 1571 + ++ ++P L D A+TL GR FA R + + A+ L A + E Sbjct: 2621 RRQLITCL-QNPAADLRDIAFTLGEGRTRFAFRDSVVSQSIAGALHALQAPSSTALME-- 2677 Query: 1572 VSEQAPSVVFMFSGQGAEYVNMALDLYRHEPVFRDKLSECLTILQEISGLRYQDFLFPDG 1631 Q +VFMFSGQG++Y M LY E VFR + C ILQ G+ L+P Sbjct: 2678 -RRQDRPIVFMFSGQGSQYAGMFKGLYDSEAVFRQTVDRCAVILQRY-GVDILACLYPPA 2735 Query: 1632 REQQAERHIHRQSVSQPLHFALEYSLAWLLMNWQVEPLSMIGYSIGEYVAACLAGVFSLR 1691 + + + R ++QP F +EY+ A LL + + P ++IG+S+GE VAAC AGV+S+ Sbjct: 2736 GSKTGDA-LSRTEIAQPALFVVEYACALLLQSRGIHPQALIGHSLGELVAACFAGVYSVE 2794 Query: 1692 DALFLTYHRGVLMEKLPEGLMITVPLQEADLLQILPPVLSVAAVNDE-SCIVSGSKDSIA 1750 D+L L RG LM++ G M+ V L EAD + L P + +A VN C+++G ++IA Sbjct: 2795 DSLKLVVERGRLMQRQAPGAMLAVGLSEADCARFLEPGVELATVNGPLQCVLAGDFEAIA 2854 Query: 1751 AFEALLKSRKLISMRLQISHAGHSKMLDSMISEFRECVQRVTCNPPAVPFVSSLTGDVIT 1810 E L L+ L SHA HS+M+ + V + PP + VS+ G + Sbjct: 2855 RVERQLAEEGLVGRVLDTSHAFHSRMMAPAAHALKAVVNGFSVQPPTIALVSNHNGGWFS 2914 Query: 1811 PEEAASPEHWVRHLREPVRFAEGFKKLAPQ-ENTLFIEIGPGRNLCTLVQRFMLPDRKQK 1869 + ++ ++W HL E VRF++G LA + E+ +F+E+GPGR L + ++ + P Sbjct: 2915 IDSSSQSDYWASHLLETVRFSDGIGLLADELEDPIFLEVGPGRALQSALKSYAEP---LC 2971 Query: 1870 LLDTIRVERKKAADDEYLLRTVAQLWVNGVSVDWSRFYSGEQRRRVPLPGYPFEKKRYWL 1929 +L R R +D+ L + +A LW G W++ RVPLP YPF + +W+ Sbjct: 2972 VLGCTRHARDSRSDEAALAQGIASLWRQGARFGWAQATGCTDGARVPLPTYPFARDSHWI 3031 Score = 321 bits (822), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 279/1066 (26%), Positives = 489/1066 (45%), Gaps = 84/1066 (7%) Query: 2 QEGMLFHYLKEPGSSLYFEQVSLHIASRVDLSAFEAAWQHVVSSNEMLRAVFRWEGVKEP 61 Q+ + F + E S+ Y +L I +D +A E A V LR +R+ + Sbjct: 36 QKSLWFMHQMEDASATYNVPFALRIDGALDRAALERAVDSVYQRQSALR--YRFPCIDGQ 93 Query: 62 VQIILKERSQFLQIIDVSSQGIGERSEFITKVME-DDRNSPFDLT-EGAFRVCLYQFAEA 119 I L + ++ +D+ ++ SE K E + FDL E R L A Sbjct: 94 PVIRLVDEQLLIRKVDLRAE---PDSEAALKAFEQSEARYVFDLEHEALLRATLLHCATD 150 Query: 120 DYHMIMSHHHILFDGWSTGIILNEFMESYQLFLNQQQPSA-ALKKRYKEFIGLT-RNKDK 177 ++ ++++ HHI+FDGWS I L+E +Y + + +A L + +++ L+ N ++ Sbjct: 151 EHVLLINVHHIVFDGWSMQIFLSEVASAYSALVRGSEVNAEPLNFDFGDYLSLSPSNAER 210 Query: 178 AEQERFWAGYLQEVHPVWLQDILPASPSGQQAEGKKQLRLELPLFLYEEIKQEGKYS-VS 236 A W L PV + + Q+ G++ ++P + + +K + V+ Sbjct: 211 APDIDHWQRRLAGAPPVLPLPLDNKRAAVQRYAGQR-CHFQVPEAVSDALKNLARECRVT 269 Query: 237 CYL--YTAWALLQAFYTDSRDIVFGTTISGREEALHGWEETVGLFINTLPLRLRIDPEET 294 Y+ A+++L YT D+V G+ +S R+ + E +G F+NTLP R+ + Sbjct: 270 PYMVGLAAFSVLLYRYTQEADLVIGSPMSNRQSS--DLEGVIGFFVNTLPNRIDASGSPS 327 Query: 295 FKGLLEKVFVSLNARKEYGSTPLRDI-------KRYSGMPFEKELFDTILVIENYPLQ-N 346 F LL++V S+ E+ P I + S P + LFD + E++ ++ Sbjct: 328 FVELLKRVRASVLDTFEHAHVPFDQIVEAIQPPRSLSHAPVFQVLFD--MANEDFSVELE 385 Query: 347 NLNSRNMLIDSFSYREETNYPLSIFITLW-NSIEIVVDYSSQMYSEAFIHEAAARYQLIL 405 NL +R +DS + + Y LS+ + L + ++Y + + E + +I+ Sbjct: 386 NLRTRVYTLDSCTAK----YDLSLTLALTARGMSGAIEYDTALLDERAVQGMIDSLLIIM 441 Query: 406 SSLVQHPEAPVASADFLFPEE-QRKLLLEFANTEVMVPADKTIHQLFEEQADREPDRIAL 464 + ++P+ + L E ++ L L HQ F+ A + + AL Sbjct: 442 EQVSRNPDGAIDDFSLLSCEAVEQALRLANHQPAAPQAPFAPFHQWFKRSAAQWGEADAL 501 Query: 465 HYAGQIYSYRQLNEQANQLANFLTGKGIQPNQLVGICMDRRPELLIAMLGILKSGGAYVP 524 Y + YSY QL+ +A LA L G++ V + PE++IA+L + + GG YVP Sbjct: 502 VYENRRYSYAQLDAEARVLAGHLHAAGVRRGDRVAVVQRYGPEVIIALLAVHQVGGIYVP 561 Query: 525 IDPILPEERIAAMVQDGQIEVIITVQKYTDALMGMNGKQPVRQTLLCMDQDALQGHYGLQ 584 + + + R A +++D + +++T+ + L G C+ QD L G Sbjct: 562 L--AIDDARHADLLKDIEPRLVLTLSACQEQLRGYP----------CLVQDDLPQATGTL 609 Query: 585 DILRFPHEAGIHPSTPENLAYVIYTSGSTGAPKGVMVSHGNVVNFIFGMDKRIG-FRPD- 642 F + PE++AY+I+TSGSTG PKGV VSHG+ V+ + +++ G P Sbjct: 610 HENEFEGRN----TQPEDIAYIIFTSGSTGRPKGVSVSHGSWVSLLQALEQTYGQTEPGV 665 Query: 643 DKVLALTTYSFDIFVXXXXXXXXXXXXXXXAPDWVQKDPDAILRLIEQESIDILQATPSR 702 +L + ++FD+F+ P DP+ + LI E + +L+ P+ Sbjct: 666 TGILQMANFTFDVFMSDVVRALAVGARLIMCPRQSLADPEQLYELITAERVTLLEFVPAV 725 Query: 703 MRMLVDSSLAGCLQQPGKIL-------IGGEGFPEDLYQSLRKITDQQ--IYNVYGPTET 753 +R ++ L++ G+ L G + + Y+ ++ + Q + +VYG TE Sbjct: 726 LRQMIRY-----LEETGRRLDTLRTLTCGADVWFVHEYRKMQTLCGPQTRVVSVYGVTEA 780 Query: 754 TVWSTVQEL-------EDTLSIGKPIANTGIYILSKDKHLRPLGYPGELCISGKGVAQGY 806 T S E E +L IG P+ NT +Y++ +L P PGEL I G VA GY Sbjct: 781 TCESATFEPDAGWYDPERSLPIGGPLPNTSLYLVDATLNLVPRTVPGELLIGGGAVASGY 840 Query: 807 LNQPGLTSDKFITNPYH------PG---ERLYCTGDYAYWLPDGRLQFVGRNDGQVKXXX 857 +N+P L F+T + PG +R Y TGD + DG ++F+GR+D QVK Sbjct: 841 MNRPELNEKSFLTGSFSASGRFLPGVGEQRFYRTGDLCRHMRDGTIEFLGRSDNQVKIRG 900 Query: 858 XXXXXXXXXXXXKSYPAVKDAVVIEVEEAG-DAALAAYLVTGSGFVREDFQAFLKSKLPY 916 +P V + V+ + G +A L Y+ T + + A+L +LP Sbjct: 901 FRIELGEVESVLADHPDVNECAVVTRQSPGAEAELIGYVQTRA--TAQQLNAYLGERLPG 958 Query: 917 YAVPANLYPIGEIPYTSNLKVDRKALAQMKTARMVPSGKLVEPRSKLENEVAEIWKKVLK 976 + VP L + +P T+N K+DRK+L + + S PR+ LE ++ E W+ +L Sbjct: 959 HMVPRLLVVLAALPLTANGKIDRKSLPEPDWTQ--DSRAYAAPRNSLEEQLVEDWQHLLN 1016 Query: 977 LESVGIFNRFFDIGGDSVKVIHLCNELKARLNMEIPVQTIFDYPTI 1022 + VGI + FF+ GG S+ V + ++K R + + + +F+ PT+ Sbjct: 1017 VPRVGIDDNFFESGGHSLLVTQVIAQIKKRFGVALSIANLFEGPTV 1062 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 3,066,179,860 Number of extensions: 130717270 Number of successful extensions: 351361 Number of sequences better than 1.0e-05: 4256 Number of HSP's gapped: 329147 Number of HSP's successfully gapped: 5952 Length of query: 2091 Length of database: 757,237,578 Length adjustment: 141 Effective length of query: 1950 Effective length of database: 374,408,619 Effective search space: 730096807050 Effective search space used: 730096807050 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)