BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0183.0008.p (615 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 211 4e-53 ref|NP_691698.1| hypothetical protein OB0777 [Oceanobacillus ihe... 188 4e-46 ref|ZP_00100011.1| COG2972: Predicted signal transduction protei... 186 2e-45 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 182 3e-44 ref|NP_603097.1| Two-component sensor kinase yesM [Fusobacterium... 181 3e-44 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 211 bits (537), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 163/597 (27%), Positives = 287/597 (48%), Gaps = 40/597 (6%) Query: 26 MPLRRKILISNILIVLLALMIFVLSIHRIVFNQTLGRTSASSQQEVKLVSQSMKTVFQSV 85 + +R KILI IV++ ++ V + I NQ S ++ K ++ S+ + + V Sbjct: 12 LNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTKRIAASIDFLQRDV 71 Query: 86 QNFSKFALINQDTQNVLSRDTG-ADGDVSPLKSIHNTLAAMLETEPNIDSVIIESIGGDL 144 S F +++Q QN +S + + PL A++L ++ I + + S GD Sbjct: 72 NELSSFLVLDQRIQNFISPHSDFTKYSLGPL-------ASLLASKDYISFIALYSFQGDK 124 Query: 145 YYTSNLTGVTPQSLAIYPKD----KIDAAKGGAVWVDTLKPSFLSGMTAKN---MISVCR 197 YY SN + L + + ++ G +W+ F + KN I++ R Sbjct: 125 YYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWLSLENLPF--DLIIKNNYPKIAMAR 182 Query: 198 VIMSMEKGTPIGYIYVNIDERTLARLY-HNEQDNQNPTLVVNQEGVVISAYEAALVSRTV 256 V++ P G + + I+ T+ ++Y N ++ ++ + ++ G +IS +++ T Sbjct: 183 VLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKESAFFIADRNGNIIS-FKSTFSGFTP 241 Query: 257 ED--HSLARWVKSASGGSRTERVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNG----YW 310 + + LA+++K + LV+ + W+++ +V N + Sbjct: 242 KSAQNILAKYLKDKQNV--VININSSKLLVTSSPIPTSDWRLVSVVSLKNAINSIRISFI 299 Query: 311 KIALSIAVFGLISMLSAMVLSFVFARRLTRPLSELSEVIVEVGAGNFERRAS--AGSQDE 368 + L I VF L L A ++S F+R LT PL L+ + +V GN E + S+DE Sbjct: 300 EFYLRILVFCL---LFAFLVSMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDE 356 Query: 369 VGRLGATFNEMVEHIQDLMLTIXXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMT 428 + + +N MVE I DL+ I +QI PHFLYNTLDTI A Sbjct: 357 IAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEKA 416 Query: 429 NAKEISSILKALGEFYRISLSNGQELIAAAQEKRHLESYLYIQQIRFK-KLNYRISFEPG 487 +E+S ++ +L +R++L+ G+E I EK +E YL++Q R+K K Y + Sbjct: 417 KDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDE 476 Query: 488 IESCQVPTMLLQPLVENAIHHGIRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSE 547 I +P ++LQP VENAI HG+ + E+ G E+ GE L FI++DNG GMSE Sbjct: 477 ILDYYIPKLILQPFVENAIVHGLENNSEESFVEVIG--EKEGEN--LKFIIKDNGPGMSE 532 Query: 548 E--EQRQIWLSSSE-EGEYSFGLKNIQDRIQLRFGEAYGIVLSSEPGHGVEVKVRLP 601 E E+ + ++ S E + + ++N+ +R++L +G+ Y + + S G G + + LP Sbjct: 533 ETLEKLKRFIESENIEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 >ref|NP_691698.1| hypothetical protein OB0777 [Oceanobacillus iheyensis HTE831] dbj|BAC12733.1| hypothetical conserved protein [Oceanobacillus iheyensis HTE831] Length = 577 Score = 188 bits (477), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 157/589 (26%), Positives = 285/589 (48%), Gaps = 40/589 (6%) Query: 28 LRRKILISNILIVLLALMIFVLSIHRIVFNQT-LGRTSASSQQEVKLVS---QSMKTVFQ 83 L+RK + LALMI +L + +++ QT + + + ++ + +S Q++ TVF Sbjct: 6 LKRKFIT-----FFLALMIPILFVSLLIYYQTNVALKNQAIEEATERLSRNEQNLLTVFS 60 Query: 84 SVQNFSKFALINQDTQNVL--SRDTGADGDV-SPLKSIHNTLAAMLETEPNIDSVIIESI 140 +V+ S + + +++ + + +D D ++ I L + P I+S+++E Sbjct: 61 TVEAMSSYMIYDRNFRKIFISQKDEMYQPDYQEAMEVIKGYFTFQLISNPYINSILLEGR 120 Query: 141 GGDLYYTSNLTGVTPQSLAIYPKDKIDAAKGGAVWVDTLKPSFLSGMTAKNMISVCRVIM 200 G L Q L K+ AKG VW + + K +IS+ R+I Sbjct: 121 DGHLVKHGEPVTGNEQELDKVAKE----AKGSPVWSNPYQVK-SDWNEDKYVISLTRIIN 175 Query: 201 SMEK-GTPIGYIYVNIDERTLARLYHNEQ--DNQNPTLVVNQEGVVISAYEAALVSRTVE 257 M IG + + +D+ A LY+ + Q+ +V+ +G VI + LV + Sbjct: 176 DMNNISEQIGIVRIRLDQ---AELYNQIEVRSQQSDYFIVSDKGEVILHPDVDLVGKQFP 232 Query: 258 DHSLARWVKSASGGSRTERVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNGYWKI-ALSI 316 D L +W+ S + + G+ +V +L W + + +L ++ AL Sbjct: 233 DSGLIKWIVDGVEKSYSYQDGESHLVVVKNQLTNTNWFSVTAIDEDKLAEDLTEVRALIG 292 Query: 317 AVFGLISMLSAMVLSFVFARRLTRPLSELSEVIVEVGAGNFERRASAGSQDEVGRLGATF 376 + G++ + + +F + + R L EL++ +V GN S DE+G+LG F Sbjct: 293 FLIGILFLAGLLFFTFFYHSNIKRIL-ELTKQTKQVETGNLTASVHVDSNDEIGKLGYRF 351 Query: 377 NEMVEHIQDLMLTIXXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMTNAKEISSI 436 N+MV+ IQ + T +QI PHFLYNTLD IR A + NA E S + Sbjct: 352 NKMVKTIQKHIDTEYRLKIKQKESELKVLQNQINPHFLYNTLDMIRWNARLENAPETSQL 411 Query: 437 LKALGEFYRISLSNGQELIAAAQEKRHLESYLYIQQIRF-KKLNYRISFEPGIESCQVPT 495 ++ L + +R++L+NG+ L+ +E + ++YL +Q+ R +KL+Y++ E ++ V Sbjct: 412 IERLSKIFRMNLNNGKSLVKFEEEVEYSQAYLELQKKRLGEKLDYQLVMEEQLKGYYVMK 471 Query: 496 MLLQPLVENAIHHGIRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSEEEQRQIWL 555 ++QPL+EN+I HG + +P G+ I R + ++ I DNG G +E ++ Sbjct: 472 QMIQPLIENSIQHGFKNLPRQGIIRI--HCYRDENQAVIDVI--DNGWGFNEHKK----- 522 Query: 556 SSSEEGEYSFGLKNIQDRIQLRFGEAYGI-VLSSEPGHGVEVKVRLPLI 603 + E + LKN+ DRI + FG+ YG+ +L S+ G +++ LPL+ Sbjct: 523 --NGELRAGYALKNLNDRISIVFGKLYGLTILDSD--EGAFLRMILPLL 567 >ref|ZP_00100011.1| COG2972: Predicted signal transduction protein with a C-terminal ATPase domain [Desulfitobacterium hafniense] Length = 577 Score = 186 bits (471), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 101/271 (37%), Positives = 149/271 (54%), Gaps = 9/271 (3%) Query: 331 SFVFARRLTRPLSELSEVIVEVGAGNFERRASAGSQDEVGRLGATFNEMVEHIQDLMLTI 390 S ++A + RP+ +L + + EV G+ E+ L F M++ I++LM I Sbjct: 308 SAIYASSVARPIRQLEKAMEEVEKGSLATEVGVVGSAEIASLSTHFLSMLDRIRELMQEI 367 Query: 391 XXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMTNAKEISSILKALGEFYRISLSN 450 YSQI PHFLYNTLDTI +A N + + ++ KA+ F+R+SL Sbjct: 368 RNKEQFLRASELKTLYSQINPHFLYNTLDTIVWLAEFGNTERVITVSKAMARFFRLSLRG 427 Query: 451 GQELIAAAQEKRHLESYLYIQQIRFK-KLNYRISFEPGIESCQVPTMLLQPLVENAIHHG 509 G E E H+ YL+IQ+ R++ KL+Y I E G+ +P +LLQPLVENAI+HG Sbjct: 428 GSETTTVRDELDHVRQYLFIQKERYQDKLSYEIQAEDGLMDITIPKILLQPLVENAIYHG 487 Query: 510 IRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSEEEQRQIWLSSSEEGEYSFGLKN 569 +R MP GG+ IT R GE+ L +V DNG G + E+ + L GLKN Sbjct: 488 LRKMPGGGMIRITA---RKGEKEDLFLVVEDNGGGFEDAEKGKDPLRLG-----GVGLKN 539 Query: 570 IQDRIQLRFGEAYGIVLSSEPGHGVEVKVRL 600 + +RI+L +GE YG+ +++ PG G + +RL Sbjct: 540 VAERIRLYYGEDYGLSIANRPGQGATIILRL 570 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 182 bits (461), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 126/425 (29%), Positives = 211/425 (49%), Gaps = 22/425 (5%) Query: 192 MISVCRVIMSMEKGTPIGYIYVNIDERTLARLYHNEQDNQNPTL-VVNQEGVVISAYEAA 250 +++V R I+ G G I +++ R + + + ++ L VV+Q+G I + + Sbjct: 178 VVTVVRAIIDSTTGEEKGVILIDLKLRVIEEAVRDVRLGKSGYLMVVDQKGDPIYSPAPS 237 Query: 251 LVSRTVEDHSLARWVKSASGGSRTERVGDKPYLVSLQRLDPYGWKVIHLVPTSELTNGYW 310 ++ DH S + G TE V + Y + Q+ GW +I + T + Sbjct: 238 IMYEQSFDHRF-----SQNYGIFTEEVEGERYQLMYQQSAFTGWTLIGVFSTDQSVEEVQ 292 Query: 311 KIALSIAVFGLISMLSAMVLSFVFARRLTRPLSELSEVIVEVGAGNFERRASAGSQDEVG 370 +I + F + S+ + ++RP+++L + + +G+ R QDEVG Sbjct: 293 QILFYVVTFVFFVCFVGITASYFLSYTISRPINQLMLAMQKAESGDLTSRYEGEEQDEVG 352 Query: 371 RLGATFNEMVEHIQDLMLTIXXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIRAMAVMTNA 430 RLG +FN M+E I L+ + IKPHFLYNTLDTI+ MA NA Sbjct: 353 RLGRSFNTMIEQIGKLISLTERQERKKREAELHSLQANIKPHFLYNTLDTIQWMARKKNA 412 Query: 431 KEISSILKALGEFYRISLSNGQELIAAAQEKRHLESYLYIQQIRFK-KLNYRISFEPGIE 489 +++ ++ AL + +RI LS G +I E H+++YL IQ +R+K KLNY + +E Sbjct: 413 SDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIKNYLQIQSVRYKNKLNYSLVMPSNME 472 Query: 490 SCQVPTMLLQPLVENAIHHGIRGMPDGGLCEITGSMERSGEERILCFIVRDNGKGMSEEE 549 + ++LQP+VENAI+HGI+ GL ++E E +L +RDNGKG+ E Sbjct: 473 RLSILKIVLQPIVENAIYHGIKERRGPGLI----TIEAERENDMLIIRIRDNGKGIKPET 528 Query: 550 QRQIWLSSS---EEGEYS--------FGLKNIQDRIQLRFGEAYGIVLSSEPGHGVEVKV 598 +Q+ + + E+G+ +GL N+ R++L FGE YG+ + S G V + Sbjct: 529 LQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLRLTFGEPYGVKIDSVFNEGTVVTI 588 Query: 599 RLPLI 603 P++ Sbjct: 589 FHPIL 593 >ref|NP_603097.1| Two-component sensor kinase yesM [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] gb|AAL94396.1| Two-component sensor kinase yesM [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] Length = 552 Score = 181 bits (460), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 172/600 (28%), Positives = 277/600 (46%), Gaps = 75/600 (12%) Query: 24 QNMPLRRKI----LISNILIVLLALMIFVLSIHRIVFNQTLGRTSASSQQEVKLVSQSMK 79 N PL KI LI+N+++VLL IF S ++ + + + + ++ + M Sbjct: 4 NNKPLNIKIGFYFLITNLVLVLLLGSIFYFSSSSLLIQKEISAKTEAIEKSGNYIELYM- 62 Query: 80 TVFQSVQNFSKFALINQDTQNVLSRDTGA-----DGDVSPLKSIHNTLAAMLETEPNIDS 134 +K ++Q V+S D G + D S I N + L T+P I S Sbjct: 63 ---------NKLTTLSQ----VISHDKGVYDYLKNKDESEKNRILNIIDNTLSTDPYIKS 109 Query: 135 VIIESIGGDLYYTSNLTGVTPQSLAIYPKDK--IDAAKGGAVWVDTL-KPSF-LSGMTAK 190 +I+ I D SN V + + K++ +++ ++ L K +F L GM Sbjct: 110 IIL--IRKDGAVISNEKNVNMEVSSDMMKEEWYVNSLMNPMPVLNPLRKQNFSLDGMDDW 167 Query: 191 NMISVCRVIMSMEKGTPIGYIYVNIDERTLARLYHNEQDNQNPTLVVNQEGVVISAYEAA 250 +ISV R I G +G + +++ + L N++ +N +V+ E I Y Sbjct: 168 -VISVSREIADT-NGENLGVLLIDVKYQALHEYLQNQETGKNSDIVILDEDNRI-VYYKE 224 Query: 251 LVSRTVEDHSLARWVKSASGGSRTERVGDKPYLVSLQRLDPYGWKVIHLVPTSE---LTN 307 + T ++ L G +R E Y + W +I + E L N Sbjct: 225 IPYDTSQEKYLKNLKNIEEGYNRKENTVTVKYPIKNTH-----WTLIEISYMQEIDSLKN 279 Query: 308 GYWKIALSIAVFGLISMLSAMVLSFVFARRLTRPLSELSEVIVEVGAGNFERRASAGSQD 367 ++++ I + L S+L ++++ RR+T+P+ EL E NF S + Sbjct: 280 HFFEM---IVISCLASLLITVLINISVLRRITKPIKEL-----EQHMNNFNNDLSKINLK 331 Query: 368 -----EVGRLGATFNEMVEHIQDLMLTIXXXXXXXXXXXXXXXYSQIKPHFLYNTLDTIR 422 E+ L FNEM++ I+ L YSQI PHFLYNTLDTI Sbjct: 332 GDVSIEILSLQNHFNEMIDKIKYL-----------REYEINALYSQINPHFLYNTLDTII 380 Query: 423 AMAVMTNAKEISSILKALGEFYRISLSNGQELIAAAQEKRHLESYLYIQQIRFK-KLNYR 481 MA + +++ SI KAL F+RISLSNG+E I +E H++ YLYIQ+ R++ KL Y+ Sbjct: 381 WMAEFQDTEKVISITKALSNFFRISLSNGKEKIPLKEEINHIKEYLYIQKQRYEDKLEYK 440 Query: 482 ISFEPGIESCQVPTMLLQPLVENAIHHGIRGMPDGGLCEITGSMERSGEERILCFIVRDN 541 IS + +E+ +VP ++LQP VENAI+HGI+ + G+ I + + E I+ DN Sbjct: 441 ISIQEELENIEVPKIILQPFVENAIYHGIKNLDTTGIISIYSQIVENKIE----LIIEDN 496 Query: 542 GKGMSEEEQRQIWLSSSEEGEYSFGLKNIQDRIQLRFGEAYGIVLSSEPGHGVEVKVRLP 601 G G E ++Q + G+KN+ RIQ +G+ YG + S G + + LP Sbjct: 497 GIGF-EAAKKQALMKMG-----GVGIKNVNKRIQYYYGKEYGAKIDSSFKTGARIIITLP 550 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 805,894,484 Number of extensions: 31295470 Number of successful extensions: 87436 Number of sequences better than 1.0e-05: 230 Number of HSP's gapped: 87327 Number of HSP's successfully gapped: 230 Length of query: 615 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 483 Effective length of database: 398,844,510 Effective search space: 192641898330 Effective search space used: 192641898330 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)