BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0167.0009.p (614 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242775.1| two-component sensor histidine kinase [Bacillus... 452 e-125 ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halo... 209 2e-52 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 172 2e-41 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 164 4e-39 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 163 1e-38 >ref|NP_242775.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83888 two-component sensor histidine kinase BH1909 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05628.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 597 Score = 452 bits (1162), Expect = e-125, Method: Compositional matrix adjust. Identities = 240/589 (40%), Positives = 357/589 (60%), Gaps = 2/589 (0%) Query: 21 MFHWFVKLMNDIKIRNKXXXXXXXXXXXXXXXXXXXXTFEMRTMAFDNALEQASTNVDRV 80 M+ ++ +ND+K+R+K T E+R+ A +A++Q+ NV+RV Sbjct: 1 MYSTLIQTINDMKLRDKLMFMFVVVVFFPMMIVGIFLTNELRSNAIQDAIQQSRVNVERV 60 Query: 81 RKRTEEVIGVSQDISYRLNNDTRLKRLAVRKYESIYEVVKAYQDYTDVREYIRLYSEISN 140 ++RT EV+ V I+ L D R L ++YE+ Y+VV AY Y + Y++ YSEI N Sbjct: 61 KERTTEVLNVPVLIANNLQFDERFIELVNQEYETTYDVVDAYLQYMNFTNYLQYYSEIHN 120 Query: 141 IRLYTDNSSLLNNWELINPSPAIKESEWYQRAQRYEGLVGWEYIEDE-RDHHKYLSLVRK 199 ++ Y++N+SL+NNW +I P EW++ A W Y+EDE + + YLS+V++ Sbjct: 121 MKYYSENTSLMNNWVII-PVEHEAGEEWFKEAMADPAYYRWFYLEDETKKNQAYLSMVKR 179 Query: 200 IELEGSSKTGVLVINVNSNKLTSILNQESFDTMIVDDQNNIIASNRKEREGKTLADISFD 259 + GVLVI V+ KL IL QESF TMIVD++N I A+N++E GK L ++ Sbjct: 180 LNFLEYGSAGVLVITVDPRKLDRILQQESFTTMIVDERNRIAATNQREYIGKDLHEVIDF 239 Query: 260 TKLLGRGSGSYEAVVEGEPSQIVIDELSPQASRNALRVVSVFSIDSIVKEPNRIIRLALS 319 +++ G YE + GEPSQI++D L+ Q S++ L+++S+ + + I+K+ R+ + + Sbjct: 240 HEMIQEGPAIYEGKMNGEPSQIIVDYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGAT 299 Query: 320 VIAIXXXXXXXXXXXXXXXXXXXXXXXXKHINRVGTGDFDTSLQIDGKDEIALLARQFNS 379 V + IN+V +GD T + +DGKDEI L+ QFN Sbjct: 300 VTMGGMAVAVLLIVHFSWLISKRLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQ 359 Query: 380 MVRSIHDLMLEVQVSNEQNSLLQQKQNDIRFKMLASQINPHFLFNALESIRMEAHMKNQQ 439 MV ++ L+ +V +N Q LL++ QN+I+ KMLASQINPHFLFN LESIRM++HMK + Sbjct: 360 MVANLRSLIHQVHETNRQKRLLEKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGET 419 Query: 440 EIARVVRLLGQMMRSSLEVGRSKVTLKQELDMVRCYLEIQQFRYEERLKYHFIVDPAIES 499 EIA+VV+ LG++MR SLEV + L+ ELDMVRCYLEIQ FRY +RL Y +DP E Sbjct: 420 EIAKVVKQLGKLMRKSLEVTGHHIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEM 479 Query: 500 LSMPPLIIQPLVENAVIHGLDNTLEGAVVTVEIRYEQEHAVFTITDNGVGITQDRLEQVR 559 + + PLIIQPLVENAVIHGL+ T +G VT+ + D+G G+ +++LE ++ Sbjct: 480 VEILPLIIQPLVENAVIHGLERTEDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKLEAIQ 539 Query: 560 STLETQEEQEGARIGLRNVHDRLKLSYGEKYGLTIESHPDEGTRISFRI 608 + L +E +G +IGL NVH RL+L+YG+ GL IES +GT + F I Sbjct: 540 NMLHHPQEVDGNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTI 588 >ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halodurans] pir||F83913 hypothetical protein BH2110 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05829.1| BH2110~unknown conserved protein [Bacillus halodurans] Length = 585 Score = 209 bits (531), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 151/556 (27%), Positives = 268/556 (48%), Gaps = 43/556 (7%) Query: 63 TMAFDNALEQASTNVDRVRKRTEEVIGVSQDISYRLNNDTRLKRLAVRKYESIYEVVKAY 122 T F+NA++QA IG+S +TR+ +YE+ + ++AY Sbjct: 60 TNEFNNAVDQA--------------IGISSGFY----TNTRIYDFFETEYETAIDYIEAY 101 Query: 123 QDYTDVREYIR---LYSEISNIRLYTDNSSLLNNWELINPSPAIKESEWYQRAQRYEGLV 179 Y +REY R LY I +I YTDN S + + + KE +WY+ + Sbjct: 102 DFY--LREYSRFSPLYYSIQSISFYTDNPSFIYAGGIRPLTEHTKEEKWYRLLTEANHPI 159 Query: 180 GWEYIEDERDHHKYLSLVRKIELEGSSKTGVLVINVNSNKLT--SILNQESF--DTMIVD 235 + S++R+++ + ++ ++ N LT I N +F + +++ Sbjct: 160 IIR--TNPATDSGLFSVIRELDYHKNKYNHKKIVRIDLNPLTIKQIFNNAAFTGEVYLLN 217 Query: 236 DQNNIIASNRKEREGKTLADISFDTKLLGRGSGSYEAVVEGEPSQIVIDELSPQASRNAL 295 + NI S+ +E +T + FD A+ E + + + Q Sbjct: 218 GERNIEFSSNEEVNWRT-EQLHFD------------ALEFPEDTIFTKERMLSQNYLEGW 264 Query: 296 RVVSVFSIDSIVKEPNRIIRLALSVIAIXXXXXXXXXXXXXXXXXXXXXXXXKHINRVGT 355 RV S + I++E + + + +I KH+ R+ Sbjct: 265 RVAGTISENEILEELYKSREFIVILASINLLFPTLLIVLISKSIHSRLLRVLKHMKRMKK 324 Query: 356 GDFDTSLQIDGKDEIALLARQFNSMVRSIHDLMLEVQVSNEQNSLLQQKQNDIRFKMLAS 415 FD KDEI L +FN M ++I+ L+ EV SN + LQ ++ + L S Sbjct: 325 QKFDIINFPGDKDEIGELTNEFNKMSQTINRLINEVYASNIEKKDLQLREKQAQLSALQS 384 Query: 416 QINPHFLFNALESIRMEAHMKNQQEIARVVRLLGQMMRSSLEVGRSKVTLKQELDMVRCY 475 QINPHFLFNALE+IRM + +K ++E A++++ + ++ R+SL G+ VT++ EL ++ C+ Sbjct: 385 QINPHFLFNALETIRMRSMIKGEKETAKIIQNMAKIFRNSLTWGKDWVTVRDELCLIICF 444 Query: 476 LEIQQFRYEERLKYHFIVDPAIESLSMPPLIIQPLVENAVIHGLDNTLEGAVVTVEIRYE 535 LEIQ++R+ ++++Y +D +P ++ P VENA IHG+++ E ++ + + Sbjct: 445 LEIQKYRFGDKMEYELDIDEEAYDYIIPNMVFLPFVENASIHGIESVKEKGIIQIRVEKN 504 Query: 536 QEHAVFTITDNGVGITQDRLEQVRSTLETQEEQEGARIGLRNVHDRLKLSYGEKYGLTIE 595 V+ I+DNG G+ +++L + TL+ EE G +G++NV+ RLKL Y + +I Sbjct: 505 DGEIVYEISDNGAGMDEEKLASLIETLK-NEENMGENVGIKNVYYRLKLHYKNHFDFSIN 563 Query: 596 SHPDEGTRISFRIPME 611 S P +GT + ++P E Sbjct: 564 SRPGQGTTVQIKLPAE 579 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 172 bits (436), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 144/560 (25%), Positives = 267/560 (47%), Gaps = 48/560 (8%) Query: 77 VDRVRKRTEEVIGVSQDISYRLNNDTRLKRLAVRKYESI-----YEVVKAYQDYTDVREY 131 +D+V E I Q+++Y ++ + +++ E + YE+ K Q++T Sbjct: 55 IDKVNSTIEAHIENVQNMTYFISLHSNIQQFLDGTLEHLGPDEEYEISKFLQNFTT---- 110 Query: 132 IRLYSEISNIRLYTDNSSLLNNWELINPSPAIKESEWYQRAQRYEG---LVGWEYIEDER 188 LY EI+ I + L+N S + + WY++A +G L+G Sbjct: 111 --LYPEIAGILVVNQQGDYLSNELYTRSSFNLNQESWYRQAVENKGIAKLIGKPQGRRIT 168 Query: 189 DHHKY-----LSLVRKI-ELEGSSKTGVLVIN----VNSNKLTSILNQESFDTMIVDDQN 238 H Y +++VR I + + GV++I+ V + + +S M+VD + Sbjct: 169 SHVHYREDEVVTVVRAIIDSTTGEEKGVILIDLKLRVIEEAVRDVRLGKSGYLMVVDQKG 228 Query: 239 NIIASNRKEREGKTLADISFDTKLLGRGSGSYEAVVEGEPSQIVIDELSPQASRNALRVV 298 + I S + + SFD + + G + VEGE Q+ + Q++ ++ Sbjct: 229 DPIYSPAP----SIMYEQSFDHRF-SQNYGIFTEEVEGERYQL----MYQQSAFTGWTLI 279 Query: 299 SVFSIDSIVKEPNRIIRLALSVIAIXXXXXXXXXXXXXXXXXXXXXXXXKHINRVGTGDF 358 VFS D V+E +I+ ++ + + + +GD Sbjct: 280 GVFSTDQSVEEVQQILFYVVTFVFFVCFVGITASYFLSYTISRPINQLMLAMQKAESGDL 339 Query: 359 DTSLQIDGKDEIALLARQFNSMVRSIHDLMLEVQVSNEQNSLLQQKQNDIRFKMLASQIN 418 + + + +DE+ L R FN+M+ I L + ++ Q ++K+ + L + I Sbjct: 340 TSRYEGEEQDEVGRLGRSFNTMIEQIGKL---ISLTERQ----ERKKREAELHSLQANIK 392 Query: 419 PHFLFNALESIRMEAHMKNQQEIARVVRLLGQMMRSSLEVGRSKVTLKQELDMVRCYLEI 478 PHFL+N L++I+ A KN ++A +V L ++ R L G + + L E++ ++ YL+I Sbjct: 393 PHFLYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIKNYLQI 452 Query: 479 QQFRYEERLKYHFIVDPAIESLSMPPLIIQPLVENAVIHGLDNTLEGAVVTVEIRYEQEH 538 Q RY+ +L Y ++ +E LS+ +++QP+VENA+ HG+ ++T+E E + Sbjct: 453 QSVRYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIYHGIKERRGPGLITIEAERENDM 512 Query: 539 AVFTITDNGVGITQDRLEQVRST----LETQEEQEGARI----GLRNVHDRLKLSYGEKY 590 + I DNG GI + L+Q+R+ LE +++ G R+ GL NVH RL+L++GE Y Sbjct: 513 LIIRIRDNGKGIKPETLQQLRTNVNLFLEKGDKEGGQRLTKGYGLINVHARLRLTFGEPY 572 Query: 591 GLTIESHPDEGTRISFRIPM 610 G+ I+S +EGT ++ P+ Sbjct: 573 GVKIDSVFNEGTVVTIFHPI 592 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 164 bits (416), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 135/509 (26%), Positives = 247/509 (48%), Gaps = 38/509 (7%) Query: 121 AYQDYTDVREYIRLYSEISNIRLYT-DNSSLLNNWELINPSPAIKESEWYQRAQRYEGLV 179 A +DY +I LYS + ++ D+S+L+ + ELI K + +Y+ G Sbjct: 107 ASKDYIS---FIALYSFQGDKYYFSNDSSTLIMDLELI------KRTSFYREVLEKNGAP 157 Query: 180 GWEYIEDE------RDHHKYLSLVRKI-ELEGSSKTGVLVINVNSNKLTSILNQ---ESF 229 W +E+ ++++ +++ R + + G+LVI +N + + ++ E Sbjct: 158 MWLSLENLPFDLIIKNNYPKIAMARVLLDFNTYKPEGLLVICINIPTIEKVYSENLKEKE 217 Query: 230 DTMIVDDQNNIIASNRKEREGKTLADISFDTKLLGRGSGSYEAVVEGEPSQIVIDELSPQ 289 + D+N I S + G T +L + + VV S ++ SP Sbjct: 218 SAFFIADRNGNIISFKSTFSGFTPKSAQ---NILAKYLKDKQNVVININSSKLLVTSSPI 274 Query: 290 ASRNALRVVSVFSIDSIVKEPN-RIIRLALSVIAIXXXXXXXXXXXXXXXXXXXXXXXXK 348 + + R+VSV S+ + + I L ++ Sbjct: 275 PTSD-WRLVSVVSLKNAINSIRISFIEFYLRILVFCLLFAFLVSMYFSRALTHPLERLAN 333 Query: 349 HINRVGTGDFDTSLQID--GKDEIALLARQFNSMVRSIHDLMLEVQVSNEQNSLLQQKQN 406 + +V G+ + ++ + KDEIA++ +++N MV I+DL+ N +L+ + N Sbjct: 334 SMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLI---------NRILKLEIN 384 Query: 407 --DIRFKMLASQINPHFLFNALESIRMEAHMKNQQEIARVVRLLGQMMRSSLEVGRSKVT 464 + K L +QINPHFL+N L++I +A +E++ ++ L ++ R +L G + Sbjct: 385 KREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQ 444 Query: 465 LKQELDMVRCYLEIQQFRYEERLKYHFIVDPAIESLSMPPLIIQPLVENAVIHGLDNTLE 524 ++ E +++ YL +Q RY+ + KY + I +P LI+QP VENA++HGL+N E Sbjct: 445 VRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSE 504 Query: 525 GAVVTVEIRYEQEHAVFTITDNGVGITQDRLEQVRSTLETQEEQEGARIGLRNVHDRLKL 584 + V V E E+ F I DNG G++++ LE+++ +E++ +E +RNV++RL+L Sbjct: 505 ESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYAIRNVNERLRL 564 Query: 585 SYGEKYGLTIESHPDEGTRISFRIPMEVA 613 YG+KY L IES EGT IS +P ++ Sbjct: 565 YYGDKYELKIESRQGEGTTISLILPESIS 593 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 163 bits (413), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 90/259 (34%), Positives = 148/259 (57%), Gaps = 11/259 (4%) Query: 353 VGTGDFDTSLQIDGKDEIALLARQFNSMVRSIHDLMLEV-QVSNEQNSLLQQKQNDIRFK 411 + G+FD+ +I DEI++L + FN M+ I L+ +V QV ++ S + Sbjct: 320 ISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQKRSA--------ELR 371 Query: 412 MLASQINPHFLFNALESIRMEAHMKNQQEIARVVRLLGQMMRSSLEVGRSKVTLKQELDM 471 +L SQINPHFL+N L++I+ +A N E+ ++ L R SL G+ +T+ E+ Sbjct: 372 VLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITISDEVAH 431 Query: 472 VRCYLEIQQFRYEERLKYHFIVDPAIESLSMPPLIIQPLVENAVIHGLDNTLEGAVVTVE 531 V YLEIQ+ RY++++ Y VD +++ +P LI+QPLVEN++ HGL ++ V Sbjct: 432 VSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGLKLQKHKGIINVS 491 Query: 532 IRYEQEHAVFTITDNGVGITQDRLEQVRSTLETQEEQEGARIGLRNVHDRLKLSYGEKYG 591 I + + DNG+G+ ++L +R L E E GL N+++RLKL++G+KY Sbjct: 492 ISSKDGFLFIKVIDNGLGMDVEQLRTLRKNL--WESIETNHYGLYNINERLKLAFGKKYS 549 Query: 592 LTIESHPDEGTRISFRIPM 610 + I+S GT++ RIP+ Sbjct: 550 IEIKSELKIGTQVLLRIPL 568 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.317 0.134 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 757,111,184 Number of extensions: 28537487 Number of successful extensions: 99625 Number of sequences better than 1.0e-05: 192 Number of HSP's gapped: 99464 Number of HSP's successfully gapped: 192 Length of query: 614 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 482 Effective length of database: 398,844,510 Effective search space: 192243053820 Effective search space used: 192243053820 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)