BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0164.0007.p (309 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_653903.1| tetR, Bacterial regulatory proteins, tetR famil... 125 1e-27 ref|NP_981859.1| transcriptional regulator, TetR family [Bacillu... 122 8e-27 ref|NP_835095.1| Transcriptional regulator, TetR family [Bacillu... 119 8e-26 ref|NP_391183.1| similar to hypothetical proteins from B. subtil... 117 4e-25 ref|NP_388552.1| similar to transcriptional regulator (TetR/AcrR... 115 1e-24 >ref|NP_653903.1| tetR, Bacterial regulatory proteins, tetR family [Bacillus anthracis A2012] ref|NP_847831.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] gb|AAP29317.1| transcriptional regulator, TetR family [Bacillus anthracis str. Ames] Length = 290 Score = 125 bits (314), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 82/274 (29%), Positives = 145/274 (52%), Gaps = 3/274 (1%) Query: 8 DKKEQIIKTAMQLFAVKGSSSTSMQEIAELCGISKGSLYLVFKSKEELERSIYIYCFRMI 67 +K+ II+ AM+LFA KG ++TS+QEI CGISKG+ YL FKSKEEL + Y + I Sbjct: 3 EKERLIIEMAMKLFATKGVNATSVQEIVTACGISKGAFYLYFKSKEELLLATLRYYYDKI 62 Query: 68 RDPLQQEEQNSSRTPREKLRNQIEILLHHVYELREFFQRQFQELAGKGMTDAPEWLRKIN 127 ++ + E+ S PREK Q+ + + + +EF +E A + E++ ++ Sbjct: 63 QNKMMDIEK-ESLLPREKFAKQLHCQFNDIQKHKEFIIMHARENAIPFNKEVEEFMMRMK 121 Query: 128 GPLLKWSQNKLETLYGKEVLPYTGELFLLGHGMIHSYIFLLFNHESFVSIPRLANHLVDV 187 + +N L ++YG +V+PY +L ++ G+ Y+ L+ + + ++ ++ Sbjct: 122 LESHAFYRNSLLSIYGDKVMPYLLDLVIMVEGICRGYLELIILQAPEIDLSYVSAFILKR 181 Query: 188 LDIVVAGLHAGRPAPLFSSIALESWMENYEAGSHRNPLQLLKEMKERLHAGSGADPHSTE 247 +D +V GL P+ L ++ E + LKE+ + + AD E Sbjct: 182 VDDLVDGLVKSSEEPVLHEEKLGEFLCKSELIKEQVKEHFLKEII--VFKRTLADQLEDE 239 Query: 248 DALESIAILESEILMPHPRKAIILGMIGNLQSYP 281 + L ++ +LE+E+ +P+PR +I GM+ NL+ YP Sbjct: 240 ELLVTLDVLEAEMRLPNPRIPVIQGMLSNLEVYP 273 >ref|NP_981859.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] gb|AAS44467.1| transcriptional regulator, TetR family [Bacillus cereus ATCC 10987] Length = 290 Score = 122 bits (307), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 82/276 (29%), Positives = 146/276 (52%), Gaps = 3/276 (1%) Query: 8 DKKEQIIKTAMQLFAVKGSSSTSMQEIAELCGISKGSLYLVFKSKEELERSIYIYCFRMI 67 +K+ II+ AM+LFA KG ++TS+QEI CGISKG+ YL FKSKEEL + Y + I Sbjct: 3 EKERLIIEMAMKLFATKGVNATSVQEIVTACGISKGAFYLYFKSKEELLLATLRYYYDKI 62 Query: 68 RDPLQQEEQNSSRTPREKLRNQIEILLHHVYELREFFQRQFQELAGKGMTDAPEWLRKIN 127 ++ + E+ S PREK Q+ + + + +EF +E A + E++ ++ Sbjct: 63 QNKMMDIEKESL-LPREKFAKQLHCQFNDIQKHKEFIIMHARENAIPFNKEVEEFMMRMK 121 Query: 128 GPLLKWSQNKLETLYGKEVLPYTGELFLLGHGMIHSYIFLLFNHESFVSIPRLANHLVDV 187 + +N L ++YG +V+PY +L ++ G+ Y+ L+ + + ++ ++ Sbjct: 122 LESHAFYRNSLLSIYGDKVMPYLLDLVIMVEGICRGYLELIILQAPEIDLSYVSAFILKR 181 Query: 188 LDIVVAGLHAGRPAPLFSSIALESWMENYEAGSHRNPLQLLKEMKERLHAGSGADPHSTE 247 +D +V GL P+ L ++ E + LKE+ + + AD E Sbjct: 182 VDHLVDGLVKSSEEPVLHEERLGEFLCKSELIKEQVKEHFLKEII--VFKRTLADQLEDE 239 Query: 248 DALESIAILESEILMPHPRKAIILGMIGNLQSYPAV 283 + L ++ +LE+E+ M +PR +I GM+ NL++YP + Sbjct: 240 ELLVTLDVLEAEMRMQNPRIPVIQGMLFNLEAYPTL 275 >ref|NP_835095.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] gb|AAP12296.1| Transcriptional regulator, TetR family [Bacillus cereus ATCC 14579] Length = 291 Score = 119 bits (298), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 81/274 (29%), Positives = 145/274 (52%), Gaps = 3/274 (1%) Query: 8 DKKEQIIKTAMQLFAVKGSSSTSMQEIAELCGISKGSLYLVFKSKEELERSIYIYCFRMI 67 +K+ II++AM+LFA KG ++TS+QEI GISKG+ YL FKSK+EL + Y + I Sbjct: 3 EKERLIIESAMKLFATKGVNATSVQEIVTASGISKGAFYLYFKSKDELLLATLRYYYDKI 62 Query: 68 RDPLQQEEQNSSRTPREKLRNQIEILLHHVYELREFFQRQFQELAGKGMTDAPEWLRKIN 127 + + EQ S PREK Q+ + + + +EF +E A + E++ ++ Sbjct: 63 QKKMLDIEQ-ESLLPREKFAKQLHCQFNDIQKHKEFIIMHARENAIPFNKEVEEFMMRMK 121 Query: 128 GPLLKWSQNKLETLYGKEVLPYTGELFLLGHGMIHSYIFLLFNHESFVSIPRLANHLVDV 187 + +N L ++YG++V+PY +L ++ G+ Y+ L+ + + +A ++ Sbjct: 122 LESHAFYRNSLLSIYGEKVMPYLLDLVIMVEGICRGYLELIILQAPEIDLSYVAAFILKR 181 Query: 188 LDIVVAGLHAGRPAPLFSSIALESWMENYEAGSHRNPLQLLKEMKERLHAGSGADPHSTE 247 +D +V GL P+ L ++ E + LKE+ + + AD + Sbjct: 182 VDNLVDGLVESSEEPILHEEKLGEFLCKSELIKEQVKEHFLKEII--VFKRTLADQLEDD 239 Query: 248 DALESIAILESEILMPHPRKAIILGMIGNLQSYP 281 + L ++ +LE+EI + +PR +I GM+ NL++YP Sbjct: 240 ELLVTLDVLEAEIRLLNPRIPVIRGMLANLEAYP 273 >ref|NP_391183.1| similar to hypothetical proteins from B. subtilis [Bacillus subtilis] sp|P40950|YUXN_BACSU Putative HTH-type transcriptional regulator yuxN pir||F70025 conserved hypothetical protein yuxN - Bacillus subtilis emb|CAB15293.1| yuxN [Bacillus subtilis subsp. subtilis str. 168] emb|CAA11750.1| YuxN protein [Bacillus subtilis] Length = 291 Score = 117 bits (292), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 91/291 (31%), Positives = 153/291 (52%), Gaps = 13/291 (4%) Query: 8 DKKEQIIKTAMQLFAVKGSSSTSMQEIAELCGISKGSLYLVFKSKEELERSIYIYCF-RM 66 +K++ II+TA++LFA KG +STS+QEIA+ C ISKG+ Y+ F SKE L S+ Y + + Sbjct: 3 EKEKLIIETALKLFAQKGYNSTSVQEIAKECKISKGAFYIYFPSKEALLLSMLNYYYDKT 62 Query: 67 IRDPLQQEEQNSSRTPREKLRNQIEILLHHVYELREFFQRQFQELAGKGMTDAPEWLRKI 126 L + + S PR R Q+ +L ++ E ++F Q +E + + + +KI Sbjct: 63 FTRILNIKTKGDS--PRTAYRKQLTVLYENILEHKDFISMQLKEGSLPYTEEVEQCAKKI 120 Query: 127 NGPLLKWSQNKLETLYGKEVLPYTGELFLLGHGMIHSYIFLLFNHESFVSIPRLANHLVD 186 L++ + L +YGK+ PYT EL L G+ Y+ + V +LA+ +++ Sbjct: 121 RQSSLQFHIDSLLNIYGKKAEPYTAELCFLIEGISQIYLECMILLGYTVKPSQLADIIMN 180 Query: 187 VLDIVVAGLHAGRPAPLFSSIALESWMENYEAGSHRNPLQL----LKEMKERLHAGSGAD 242 +D +V G+ P I LE + +H P L +K +++++++ + Sbjct: 181 RIDDMVKGMSERNDKPF---ITLEEASSLFGPLTHGRPDPLTESIVKSLRDKINS---LN 234 Query: 243 PHSTEDALESIAILESEILMPHPRKAIILGMIGNLQSYPAVHPQLEDLKKL 293 +S+ + ES+ ILE+E+ P+ AII GMI NL A+ E LK L Sbjct: 235 TNSSLELSESLDILEAEMKKKTPKLAIIKGMIHNLTESEALAKDAEQLKYL 285 >ref|NP_388552.1| similar to transcriptional regulator (TetR/AcrR family) [Bacillus subtilis] sp|O31500|YERO_BACSU Putative HTH-type transcriptional regulator yerO pir||D69795 transcription regulator TetR/AcrR family homolog yerO - Bacillus subtilis emb|CAB12490.1| yerO [Bacillus subtilis subsp. subtilis str. 168] Length = 289 Score = 115 bits (288), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 86/275 (31%), Positives = 141/275 (51%), Gaps = 19/275 (6%) Query: 7 TDKKEQIIKTAMQLFAVKGSSSTSMQEIAELCGISKGSLYLVFKSKEELERSIYIYCFRM 66 +KKE+IIKT+++LFA KG ++T++QEIA CGISKG+ YL FKSKE L S Y M Sbjct: 2 NEKKERIIKTSIRLFAKKGFAATTIQEIASECGISKGAFYLHFKSKEALLLSACEYYIGM 61 Query: 67 IRDPLQQ-EEQNSSRTPREKLRNQIEILLHHVYELREFFQRQFQELAGKGMTDAPEWLRK 125 + ++ EE + + P+E L+ QI + ++F E + ++ K Sbjct: 62 SMNKMKNIEEDLAGKPPKEVLKKQIGAQFEDFRDHKDFIVLLLTENIIPENQEIKQYFYK 121 Query: 126 INGPLLKWSQNKLETLYGKEVLPYTGELFLLGHGMIHSYI-FLLFNHESFVSIPRLANHL 184 + K +N L YG+ + Y +L ++ G++HSY+ ++FN E + ++ + Sbjct: 122 VTMETDKLYRNALLVSYGEGIERYVADLSIMARGIVHSYMNVMVFNGELNIDAEEISAFI 181 Query: 185 VDVLDIVVAGLHAGRPAPLFSSIALESWMENYEAGSHRNPLQLLKEMKERLHAGSGADPH 244 ++ LD +V GL P+ S + AG QLL+++++ + Sbjct: 182 IERLDDLVQGLSRSALNPIVS----KDIFNPMPAGKD----QLLEDIQK-------VKEN 226 Query: 245 ST--EDALESIAILESEILMPHPRKAIILGMIGNL 277 ST ED S+ ++E E+ PRK II GM+ NL Sbjct: 227 STLPEDITVSLDVIEEELTQDKPRKPIIKGMLSNL 261 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 460,710,434 Number of extensions: 19395374 Number of successful extensions: 48674 Number of sequences better than 1.0e-05: 35 Number of HSP's gapped: 48681 Number of HSP's successfully gapped: 35 Length of query: 309 Length of database: 757,237,578 Length adjustment: 125 Effective length of query: 184 Effective length of database: 417,850,203 Effective search space: 76884437352 Effective search space used: 76884437352 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 126 (53.1 bits)