BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0149.0014.p (618 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_00180753.1| hypothetical protein Mther123201 [Moorella th... 116 2e-24 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 114 5e-24 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 114 8e-24 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 114 9e-24 ref|NP_358173.1| Histidine kinase [Streptococcus pneumoniae R6] ... 114 1e-23 >ref|ZP_00180753.1| hypothetical protein Mther123201 [Moorella thermoacetica ATCC 39073] Length = 607 Score = 116 bits (290), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 69/206 (33%), Positives = 116/206 (56%), Gaps = 8/206 (3%) Query: 404 HAQINPHFIYNTLDLINCRAIMAGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVE 463 +Q+NPHF++N+L+ + A++ G + K+VR+LA + R+SL + + +SL EEI V Sbjct: 407 QSQVNPHFLFNSLNTVARLALLEGAANTEKMVRALARLMRYSLYQVKGTVSLAEEIAAVR 466 Query: 464 AYLHIQKMMM-DHLQVIIQVPVGLLQARMVHLTLQPLAENAIVHGFTDRQSDCRITITAX 522 YL IQ+ D ++ ++V +QAR+ + LQPL ENAI+HG ++ IT++A Sbjct: 467 DYLFIQETRFSDRVRSRVKVEEAAMQARLPCMVLQPLVENAIIHGLEPKEEGGEITVSAR 526 Query: 523 XXXXXXXXXVEDNGTGCDVERMNEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGK 582 ++D+G G E + +A+ + G + +G G++NV+RR+Q H G Sbjct: 527 LVGDQVRVEIKDDGVGIPPE-VKKAIFDLEVRRSGKGQV---SGLGIVNVYRRLQHHFGS 582 Query: 583 --AYGLRYLPAAKGTCVEAVLPFYSD 606 A + +P KGTCV+ P+ D Sbjct: 583 NCALDVASMP-GKGTCVQLTFPYTVD 607 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 114 bits (286), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 75/251 (29%), Positives = 121/251 (48%), Gaps = 11/251 (4%) Query: 366 EVDELSQTFGSMLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAIM 425 EV L ++F +M+ + LI + A I PHF+YNTLD I A Sbjct: 350 EVGRLGRSFNTMIEQIGKLISLTERQERKKREAELHSLQANIKPHFLYNTLDTIQWMARK 409 Query: 426 AGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQKM-MMDHLQVIIQVPV 484 + + +V +L+ +FR L++G T+I L +EI+ ++ YL IQ + + L + +P Sbjct: 410 KNASDVADLVGALSKLFRIGLSKGGTIIPLVDEIEHIKNYLQIQSVRYKNKLNYSLVMPS 469 Query: 485 GLLQARMVHLTLQPLAENAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVERM 544 + + ++ + LQP+ ENAI HG +R+ ITI A + DNG G E + Sbjct: 470 NMERLSILKIVLQPIVENAIYHGIKERRGPGLITIEAERENDMLIIRIRDNGKGIKPETL 529 Query: 545 NE------ALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGLRYLPA-AKGTCV 597 + EK E G +L + GYG++NVH R++L G+ YG++ +GT V Sbjct: 530 QQLRTNVNLFLEKGDKEGGQRLTK---GYGLINVHARLRLTFGEPYGVKIDSVFNEGTVV 586 Query: 598 EAVLPFYSDSI 608 P + Sbjct: 587 TIFHPILEGGV 597 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 114 bits (284), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 77/243 (31%), Positives = 115/243 (47%), Gaps = 9/243 (3%) Query: 366 EVDELSQTFGSMLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAIM 425 E+ L Q F ML + LI K + +QINPHF+YNTLD I +A+ Sbjct: 336 EISILGQVFNQMLTDIKRLINKVYQVEKQKRSAELRVLQSQINPHFLYNTLDTIQWKALE 395 Query: 426 AGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQKM-MMDHLQVIIQVPV 484 E ++ L+N FR SL+ G+ I++ +E+ V YL IQK+ D + + V Sbjct: 396 YNAFEVVDMINYLSNFFRISLSDGKEFITISDEVAHVSNYLEIQKIRYKDKISYSMDVDS 455 Query: 485 GLLQARMVHLTLQPLAENAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVERM 544 L Q + L +QPL EN+I HG ++ I ++ V DNG G DVE++ Sbjct: 456 SLDQYLIPKLIVQPLVENSIYHGLKLQKHKGIINVSISSKDGFLFIKVIDNGLGMDVEQL 515 Query: 545 NEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGLRYLPAAK-GTCVEAVLPF 603 + S +E N YG+ N++ R++L GK Y + K GT V +P Sbjct: 516 RTLRKNLWES------IET-NHYGLYNINERLKLAFGKKYSIEIKSELKIGTQVLLRIPL 568 Query: 604 YSD 606 S+ Sbjct: 569 ISE 571 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 114 bits (284), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 72/239 (30%), Positives = 118/239 (49%), Gaps = 7/239 (2%) Query: 366 EVDELSQTFGSMLVTLHGLIEKSFXXXXXXXXXXXXXXHAQINPHFIYNTLDLINCRAIM 425 E+ + + + M+ ++ LI + AQINPHF+YNTLD I +A Sbjct: 356 EIAIVIKEYNRMVERINDLINRILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEK 415 Query: 426 AGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLHIQ-KMMMDHLQVIIQVPV 484 A D E S+++ SL+ +FR +LNRG+ I + E + +E YL +Q K + + +++ Sbjct: 416 AKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISD 475 Query: 485 GLLQARMVHLTLQPLAENAIVHGFTDRQSDCRITITAXXXXXXXXXXVEDNGTGCDVERM 544 +L + L LQP ENAIVHG + + + + ++DNG G E + Sbjct: 476 EILDYYIPKLILQPFVENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETL 535 Query: 545 NEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGLRYLP-AAKGTCVEAVLP 602 E L+ SE +E GY + NV+ R++L+ G Y L+ +GT + +LP Sbjct: 536 -EKLKRFIESEN----IEEKVGYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 >ref|NP_358173.1| Histidine kinase [Streptococcus pneumoniae R6] pir||C97944 histidine kinase (EC 2.7.3.-) [imported] - Streptococcus pneumoniae (strain R6) gb|AAK99383.1| Histidine kinase [Streptococcus pneumoniae R6] Length = 563 Score = 114 bits (284), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 118/253 (46%), Gaps = 14/253 (5%) Query: 348 LEVSGFKDTLPQQKSGIYEVDELSQTFGSMLVTLHGLIEKSFXXXXXXXXXXXXXXHAQI 407 LE++ L ++ G YE+ E+++ F +ML + L+ +QI Sbjct: 314 LEIASGAQNLRAKEVGAYELREVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQI 373 Query: 408 NPHFIYNTLDLINCRAIMAGDMESSKIVRSLANVFRFSLNRGQTLISLEEEIKQVEAYLH 467 NPHF+YNTLD I A ++ +SLA FR +LN+G+ LI L +EI V YL Sbjct: 374 NPHFLYNTLDTIIWMAEFHDSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLF 433 Query: 468 IQKMMM-DHLQVIIQVPVGLLQARMVHLTLQPLAENAIVHGFTDRQSDCRITITAXXXXX 526 IQK D L+ I V + L LQPL ENA+ HG +++ I ++ Sbjct: 434 IQKQRYGDKLEYEINENVAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDS 493 Query: 527 XXXXXVEDNGTGCDVERMNEALQEKPASEPGIKLLEPGNGYGMMNVHRRIQLHCGKAYGL 586 +ED+G G + A + L+ G G G+ NV +R++LH G Y + Sbjct: 494 GLVIRIEDDGVGF-----------QDAGDSSQSQLKRG-GVGLQNVDQRLKLHFGANYQM 541 Query: 587 RYLP-AAKGTCVE 598 + KGT VE Sbjct: 542 KIDSRPQKGTKVE 554 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.320 0.135 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 713,637,922 Number of extensions: 24844537 Number of successful extensions: 55801 Number of sequences better than 1.0e-05: 151 Number of HSP's gapped: 55561 Number of HSP's successfully gapped: 151 Length of query: 618 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 486 Effective length of database: 398,844,510 Effective search space: 193838431860 Effective search space used: 193838431860 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)