BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0126.0020.p (607 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242775.1| two-component sensor histidine kinase [Bacillus... 161 5e-38 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 149 3e-34 ref|NP_388576.1| similar to two-component sensor histidine kinas... 146 2e-33 ref|NP_621979.1| predicted ATPase [Thermoanaerobacter tengcongen... 140 7e-32 ref|NP_561490.1| two-component sensor histidine kinase [Clostrid... 140 1e-31 >ref|NP_242775.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83888 two-component sensor histidine kinase BH1909 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05628.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 597 Score = 161 bits (407), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 144/526 (27%), Positives = 236/526 (44%), Gaps = 60/526 (11%) Query: 91 LQYIMYNN-----PNISNLRFFTSNKYAREIWPIIYNERRIAGENWANEFYAQPEAVWWT 145 LQY+ + N I N+++++ N W II E AGE W E A P W Sbjct: 103 LQYMNFTNYLQYYSEIHNMKYYSENTSLMNNWVIIPVEHE-AGEEWFKEAMADPAYYRW- 160 Query: 146 IYRGPEELRGSTEGERQDYLNFASLVREVKYPLDQHLALLQVNMRLDVFFSNIYGNLQEA 205 Y E + Q YL+ + ++Y L + +LD LQ+ Sbjct: 161 FYLEDETKKN------QAYLSMVKRLNFLEYGSAGVLVITVDPRKLDRI-------LQQE 207 Query: 206 STQLLAIDRNSHLYYNGTSSFYEKIAPEDIRSEFALHTQGSEGN--FQFTHEGIPYLCL- 262 S + +D + + + K D+ H EG ++ G P + Sbjct: 208 SFTTMIVDERNRIAATNQREYIGK----DLHEVIDFHEMIQEGPAIYEGKMNGEPSQIIV 263 Query: 263 -YTSIERXXXXXXXXXXXXXXYNDMNKTRLAIGGATL----MLVLILSLITYKLLSVILK 317 Y +++ + + RL+I GAT+ M V +L ++ + L I K Sbjct: 264 DYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGATVTMGGMAVAVLLIVHFSWL--ISK 321 Query: 318 RLHLLRDSMKKVRQGDFNVEIPQLGGDEVGELGNHIRQMLSKINELIAEA--VNKQA--- 372 RL L + + +V GD +I G DE+G+L QM++ + LI + N+Q Sbjct: 322 RLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQMVANLRSLIHQVHETNRQKRLL 381 Query: 373 --SSKEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLVISDTLTSLGAMLRYNLHWTTH 430 S E +L L +QI+ HFL+NTLE+++M + ++G+ I+ + LG ++R +L T H Sbjct: 382 EKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGETEIAKVVKQLGKLMRKSLEVTGH 441 Query: 431 YVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQEILKMSLQPIVENALKYGMNA 490 ++ L E+ ++ Y+ + RYG +L L + Q EIL + +QP+VENA+ +G+ Sbjct: 442 HIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEMVEILPLIIQPLVENAVIHGLER 501 Query: 491 PGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAERLYNINLALQLDPAAAAMYAPPVNG 550 + G + I + + + + D+G G+ E+L A M P Sbjct: 502 T---EDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKL----------EAIQNMLHHPQEV 548 Query: 551 DSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESVEGEYTKVTIKV 596 D G+ IGL NVH R+QL YGKTSGL +ES +G+ T V + Sbjct: 549 D------GNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTI 588 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 149 bits (375), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 106/306 (34%), Positives = 158/306 (51%), Gaps = 29/306 (9%) Query: 308 TYKLLSVILKRLHLLRDSMKKVRQGDFNVEIPQLGGDEVGELGNHIRQMLSKINELIAEA 367 +Y L I + ++ L +M+K GD DEVG LG M+ +I +LI+ Sbjct: 313 SYFLSYTISRPINQLMLAMQKAESGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLT 372 Query: 368 VNKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLVISDTLTSLGAMLRYNLHW 427 ++ +EAEL+SL+ I HFLYNTL+ ++ +A + ++D + +L + R L Sbjct: 373 ERQERKKREAELHSLQANIKPHFLYNTLDTIQWMARKKNASDVADLVGALSKLFRIGLSK 432 Query: 428 TTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQEILKMSLQPIVENALKYG 487 + L +EI+HI+NY+ + ++RY KL L + + ILK+ LQPIVENA+ +G Sbjct: 433 GGTIIPLVDEIEHIKNYLQIQSVRYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIYHG 492 Query: 488 MN---APGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAERLY----NINLALQLDPAA 540 + PGL I I A ++D + I IRDNG GI E L N+NL L+ Sbjct: 493 IKERRGPGL------ITIEAERENDMLIIRIRDNGKGIKPETLQQLRTNVNLFLE----- 541 Query: 541 AAMYAPPVNGDSAYDTS-GSGIGLRNVHLRIQLHYGKTSGLWLESVEGEYTKVTIKVPYL 599 GD G GL NVH R++L +G+ G+ ++SV E T VTI P Sbjct: 542 --------KGDKEGGQRLTKGYGLINVHARLRLTFGEPYGVKIDSVFNEGTVVTIFHP-- 591 Query: 600 ILSGGL 605 IL GG+ Sbjct: 592 ILEGGV 597 >ref|NP_388576.1| similar to two-component sensor histidine kinase [YesN] [Bacillus subtilis] pir||D69796 two-component sensor histidine kinase homolog yesM - Bacillus subtilis emb|CAB12514.1| yesM [Bacillus subtilis subsp. subtilis str. 168] Length = 577 Score = 146 bits (368), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 95/312 (30%), Positives = 154/312 (49%), Gaps = 33/312 (10%) Query: 290 RLAIGGATLMLVLILSLITYKLLSVILKRLHLLRDSMKKVR----QGDFNVEIPQLGGDE 345 + IG L+ ++ L K+ + I + + L +MK V+ + ++ +P+ DE Sbjct: 289 KTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDE 348 Query: 346 VGELGNHIRQMLSKINELIAEAVNKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEIE 405 G L H M+ +INEL+ E V KQ KE EL +L+ QI+ HFLYNTLE++ LA+ Sbjct: 349 AGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTLESINWLAKAN 408 Query: 406 GQLVISDTLTSLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQ 465 Q IS + SLG +LR ++H V + EE +++Y+ + R+ +L+ LD+ + Sbjct: 409 QQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEERLKFTLDIDDE 468 Query: 466 YRQQEILKMSLQPIVENALKYGMNAPGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAE 525 + I K++LQP+ ENA++Y + R I I A + + I + DNG Sbjct: 469 VKHCLIPKLTLQPLAENAIQYALEP---FTRPCAIRIQAKKAKGCVCITVEDNG------ 519 Query: 526 RLYNINLALQLDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESV 585 P ++G T G GIGL N+ RI L +G+ GL + S Sbjct: 520 --------------------PGMDGRILESTGGRGIGLWNIRERISLTFGEPYGLRIHSE 559 Query: 586 EGEYTKVTIKVP 597 + T++ I +P Sbjct: 560 HEKGTRIVITIP 571 >ref|NP_621979.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM23583.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 493 Score = 140 bits (354), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 99/305 (32%), Positives = 166/305 (54%), Gaps = 31/305 (10%) Query: 301 VLILSLITYKLLSVILKRLHLLRDSMKKVRQGDFNVEIPQLG-GDEVGELGNHIRQMLSK 359 + + L TYK+ I+ HL +V +GDF V +L DE+ L +M+ Sbjct: 198 IFLAFLFTYKITKPIIDLSHL----AVRVSKGDFEVRPIELKTNDEIKVLSEAFNKMVVN 253 Query: 360 INELIAEAVNKQASS----KEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLVISDTLT 415 I + I E + KQA KEAEL +L++QI+ HFL+NTL LA +EG ++ + Sbjct: 254 IKKYIGE-IKKQAEMERKIKEAELKALQSQINPHFLFNTLNAAAQLAMMEGAEKSAEFIE 312 Query: 416 SLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQEILKMS 475 ++ + RYNL V L +EI++++ YI ++ R+G K++ +LDV ++ E+ M Sbjct: 313 NVANLFRYNLKKLDSTVTLKDEIENVKRYIYILKTRFGDKIDFKLDVEEEVLDLEMPCMI 372 Query: 476 LQPIVENALKYGMNAPGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAERLYNINLALQ 535 LQP+VENA +G+ + + GL IV+ AY++ + + +EI DNG G+ E++ Sbjct: 373 LQPVVENAFIHGL--EDVERDGL-IVLKAYKEGEKVLVEIADNGVGMEQEKI-------- 421 Query: 536 LDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTS---GLWLESVEGEYTKV 592 A A+ +P V+ +GIG+ N+ R+ + Y +S + ++S G+ TKV Sbjct: 422 --KAILALDSPDVDKKHV-----TGIGMHNIIHRLLVFYDISSVEDVIEIKSEIGKGTKV 474 Query: 593 TIKVP 597 T+K+P Sbjct: 475 TLKIP 479 >ref|NP_561490.1| two-component sensor histidine kinase [Clostridium perfringens] dbj|BAB80280.1| two-component sensor histidine kinase [Clostridium perfringens str. 13] Length = 529 Score = 140 bits (352), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 90/313 (28%), Positives = 160/313 (51%), Gaps = 28/313 (8%) Query: 285 DMNKTRLAIGGATLMLVLILSLITYKLLSVILKRLHLLRDSMKKVRQGDFNVEIPQLGGD 344 D+ R + L+ L++ + +Y L S I L+ L + MK+V +GD V + D Sbjct: 242 DIQSLRKEMTIIGLLFTLVVLIFSYFLYSSIKVPLYNLLNKMKRVSEGDLKVLVNDTYED 301 Query: 345 EVGELGNHIRQMLSKINELIAEAVNKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEI 404 E+G + ++ ML ++NELI + ++ ++ E+ L+ QI+ HFL+NTL +LK A + Sbjct: 302 EIGVISDNFDSMLKRVNELIEKTKLQEVEKRDLEIRMLQAQINPHFLFNTLNSLKWTALM 361 Query: 405 EGQLVISDTLTSLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQ 464 +S+ L+SL +LR + V + EE+++I+NY+ + IRYG +++ +V + Sbjct: 362 NQDYTVSEGLSSLAELLRNTIIDKNELVTIREELENIKNYVVIQKIRYGNSFDVQYEVDE 421 Query: 465 QYRQQEILKMSLQPIVENALKYGMNAPGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISA 524 + +++K LQPIVEN++ +G++ K I+I +++ + I I+DNG G ++ Sbjct: 422 LLLENKVIKFILQPIVENSIIHGIDE---NKENQKIIIKIMSEEENILISIKDNGKGFNS 478 Query: 525 ERLYNINLALQLDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLES 584 + + D SGIG NV RI+L +G G + S Sbjct: 479 K-------------------------EKVKDNKLSGIGWNNVDERIKLTFGLGYGTTIYS 513 Query: 585 VEGEYTKVTIKVP 597 + T V I +P Sbjct: 514 EVNKGTIVKIVIP 526 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 853,205,603 Number of extensions: 35114846 Number of successful extensions: 123893 Number of sequences better than 1.0e-05: 164 Number of HSP's gapped: 123700 Number of HSP's successfully gapped: 164 Length of query: 607 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 475 Effective length of database: 398,844,510 Effective search space: 189451142250 Effective search space used: 189451142250 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)