BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0117.0011.p (638 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 148 3e-34 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 143 2e-32 ref|NP_242775.1| two-component sensor histidine kinase [Bacillus... 139 2e-31 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 139 2e-31 ref|NP_388576.1| similar to two-component sensor histidine kinas... 139 3e-31 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 148 bits (374), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 152/635 (23%), Positives = 289/635 (45%), Gaps = 79/635 (12%) Query: 22 WWGRRSLQSRLVAAYIFIILGPCLLVSLYSY--------KSINNTYVRDAVDKNSYLLQM 73 W+ +++ +++ + I++ LL+ +SY K + N+ +RD Sbjct: 8 WFMGLNIRHKILILFYGIVVITSLLIVFFSYTISINQLKKEVGNSLLRDTK--------- 58 Query: 74 EKLHILNQIEAMERAAQMAYS----DKAVQNYLLNEHDPSLGELIDFNTTTFMNLSRIQI 129 I I+ ++R S D+ +QN++ + H DF + L+ + Sbjct: 59 ---RIAASIDFLQRDVNELSSFLVLDQRIQNFI-SPHS-------DFTKYSLGPLASLLA 107 Query: 130 NNPNIEHLRLYSGSGEVH----ELWPIIFREERVSMEPWFQKALKLEGQELW-SFQNEDP 184 + I + LYS G+ + + +I E + ++++ L+ G +W S +N Sbjct: 108 SKDYISFIALYSFQGDKYYFSNDSSTLIMDLELIKRTSFYREVLEKNGAPMWLSLENLPF 167 Query: 185 DLMQRYSGDPPKGQPKVSLLREISIPAGHHVGMIQVDMLLSRFTPKTYTD-VRDNQSQMF 243 DL+ + + P +V L P G V I + + K Y++ +++ +S F Sbjct: 168 DLIIK-NNYPKIAMARVLLDFNTYKPEGLLVICINIPTI-----EKVYSENLKEKESAFF 221 Query: 244 IAGEDLQLFTRADHSFVQDNPQLTGAIAGRLQQYAETGEWDIHYKEKGNSFLLIHTPLTE 303 IA + + + +F P+ I + + + +I+ + L+ +P+ Sbjct: 222 IADRNGNIIS-FKSTFSGFTPKSAQNILAKYLKDKQNVVININ----SSKLLVTSSPIPT 276 Query: 304 IGASLVNVVSMEGVMKDISHTRNLIIGLNIGFIVLVTAIAYVLNAFILKNL----RRLTE 359 LV+VVS++ + I R I + +V A++++ + + L RL Sbjct: 277 SDWRLVSVVSLKNAINSI---RISFIEFYLRILVFCLLFAFLVSMYFSRALTHPLERLAN 333 Query: 360 TMKKARRG--EAYTGFSIRGGGEVGELAHHFSKLMNTINTLVAQAVNKEALSKEAELRTL 417 +MKK R+G E F E+ + +++++ IN L+ + + E +EAEL+ L Sbjct: 334 SMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRILKLEINKREAELKAL 393 Query: 418 HNQIDAHFLYNTLENIKMLAEIENQRGISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIE 477 QI+ HFLYNTL+ I AE R +S+ + SL + R E++++R E IE Sbjct: 394 EAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRLFRLTLNRGEEFIQVRGEKELIE 453 Query: 478 NYIEVMNIRFEYPILLELEVDAPYLELEVLKMSLQPVVENSVKHAWAAGEEELQNRSIRI 537 Y+ + + R++ +++ L+ + K+ LQP VEN++ H EE S Sbjct: 454 RYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFVENAIVHGLENNSEE----SFVE 509 Query: 538 QISEADGD-IFIAIRDNGFGLTPERLTELHSSIYAK--EEPGADASXXXXXXXXXXXXXL 594 I E +G+ + I+DNG G++ E L +L I ++ EE A + Sbjct: 510 VIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKVGYA--------------I 555 Query: 595 RNVHQRLQLFYGEAYGLEVQSQAGEWTTVFMTLPK 629 RNV++RL+L+YG+ Y L+++S+ GE TT+ + LP+ Sbjct: 556 RNVNERLRLYYGDKYELKIESRQGEGTTISLILPE 590 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 143 bits (360), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 102/399 (25%), Positives = 192/399 (48%), Gaps = 40/399 (10%) Query: 232 YTDVRDNQSQMFIAGEDLQLFTRADHSFVQDNPQLTGAIAGRLQQYAETGEWDIHYKEKG 291 Y+ ++N + +I+ E+L Q + +G +A + ++H K+ Sbjct: 207 YSTTKENLNSNYISLEELSCIAN------QSKNKSSGTVALK----------NVHNKD-- 248 Query: 292 NSFLLIHTPLTEIGASLVNVVSMEGVMKDISHTRNLIIGLNIGFIVLVTAIAYVLNAFIL 351 ++ P TE L +V + + I+ NLI+ + + ++ ++ V++ I+ Sbjct: 249 STVFFSSVPYTE-NWILCIIVENKKIHTQINQIINLILFVGLILLLAAILLSIVISGSIV 307 Query: 352 KNLRRLTETMKKARRGEAYTGFSIRGGGEVGELAHHFSKLMNTINTLVAQAVNKEALSKE 411 K + RL M + +G + + I+ E+ L F++++ I L+ + E + Sbjct: 308 KPIHRLKSNMLEISKGNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQKRS 367 Query: 412 AELRTLHNQIDAHFLYNTLENIKMLAEIENQRGISDALTSLGGMMRYNFKWSGEYVKLRD 471 AELR L +QI+ HFLYNTL+ I+ A N + D + L R + E++ + D Sbjct: 368 AELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSDGKEFITISD 427 Query: 472 EIRHIENYIEVMNIRFEYPILLELEVDAPYLELEVLKMSLQPVVENSVKHAWAAGEEELQ 531 E+ H+ NY+E+ IR++ I ++VD+ + + K+ +QP+VENS+ H +LQ Sbjct: 428 EVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHGL-----KLQ 482 Query: 532 NRS--IRIQISEADGDIFIAIRDNGFGLTPERLTELHSSIYAKEEPGADASXXXXXXXXX 589 I + IS DG +FI + DNG G+ E+L L +++ E Sbjct: 483 KHKGIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLWESIETNHYG---------- 532 Query: 590 XXXXLRNVHQRLQLFYGEAYGLEVQSQAGEWTTVFMTLP 628 L N+++RL+L +G+ Y +E++S+ T V + +P Sbjct: 533 ----LYNINERLKLAFGKKYSIEIKSELKIGTQVLLRIP 567 >ref|NP_242775.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83888 two-component sensor histidine kinase BH1909 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05628.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 597 Score = 139 bits (351), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 124/529 (23%), Positives = 244/529 (46%), Gaps = 61/529 (11%) Query: 121 FMNLSRIQINNPNIEHLRLYSGSGEVHELWPIIFREERVSMEPWFQKALKLEGQELWSFQ 180 +MN + I +++ YS + + W II E E WF++A+ W F Sbjct: 105 YMNFTNYLQYYSEIHNMKYYSENTSLMNNWVIIPVEHEAG-EEWFKEAMADPAYYRW-FY 162 Query: 181 NEDPDLMQRYSGDPPKGQPKVSLLREISIPAGHHVGMI-------QVDMLLSRFTPKTY- 232 ED + K Q +S+++ ++ G++ ++D +L + + T Sbjct: 163 LED---------ETKKNQAYLSMVKRLNFLEYGSAGVLVITVDPRKLDRILQQESFTTMI 213 Query: 233 TDVRDN---QSQMFIAGEDLQLFTRADHSFVQDNPQL-TGAIAGRLQQYAETGEWDIHYK 288 D R+ +Q G+DL H +Q+ P + G + G Q Sbjct: 214 VDERNRIAATNQREYIGKDLHEVIDF-HEMIQEGPAIYEGKMNGEPSQIIV--------- 263 Query: 289 EKGNSFLLIHTPLTEIGASLVNVVSMEGVMKDISHTRNLIIGLNIGFIVLVTAIAYVLNA 348 +L + +E+ ++++V+ E +MKD + + +G + + + + Sbjct: 264 ----DYLTLQMSQSEL--KIISIVTKEHIMKDAKRLSIMGATVTMGGMAVAVLLIVHFSW 317 Query: 349 FILKNLRRLTETMKKARRGEAYTGFSIRGGGEVGELAHHFSKLMNTINTLVAQA--VNK- 405 I K L L+E + + G+ T + G E+G+L+ F++++ + +L+ Q N+ Sbjct: 318 LISKRLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQMVANLRSLIHQVHETNRQ 377 Query: 406 ----EALSKEAELRTLHNQIDAHFLYNTLENIKMLAEIENQRGISDALTSLGGMMRYNFK 461 E E +L+ L +QI+ HFL+NTLE+I+M + ++ + I+ + LG +MR + + Sbjct: 378 KRLLEKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGETEIAKVVKQLGKLMRKSLE 437 Query: 462 WSGEYVKLRDEIRHIENYIEVMNIRFEYPILLELEVDAPYLELEVLKMSLQPVVENSVKH 521 +G ++ LR+E+ + Y+E+ R+ + EL +D +E+L + +QP+VEN+V H Sbjct: 438 VTGHHIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEMVEILPLIIQPLVENAVIH 497 Query: 522 AWAAGEEELQNRSIRIQISEADGDIFIAIRDNGFGLTPERLTELHSSIYAKEEPGADASX 581 E+ ++ I D+ + + D+G G+ E+L + + ++ +E + Sbjct: 498 GLERTED---GGTVTISTIVNGNDLTVIVNDDGCGMDEEKLEAIQNMLHHPQEVDGNK-- 552 Query: 582 XXXXXXXXXXXXLRNVHQRLQLFYGEAYGLEVQSQAGEWTTVFMTLPKV 630 L NVH+RLQL YG+ GL ++S G+ T V T+ ++ Sbjct: 553 ----------IGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTISQI 591 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 139 bits (350), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 93/300 (31%), Positives = 154/300 (51%), Gaps = 10/300 (3%) Query: 339 VTAIAYVLNAFILKNLRRLTETMKKARRGEAYTGFSIRGGGEVGELAHHFSKLMNTINTL 398 +TA +Y L+ I + + +L M+KA G+ + + EVG L F+ ++ I L Sbjct: 310 ITA-SYFLSYTISRPINQLMLAMQKAESGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKL 368 Query: 399 VAQAVNKEALSKEAELRTLHNQIDAHFLYNTLENIKMLAEIENQRGISDALTSLGGMMRY 458 ++ +E +EAEL +L I HFLYNTL+ I+ +A +N ++D + +L + R Sbjct: 369 ISLTERQERKKREAELHSLQANIKPHFLYNTLDTIQWMARKKNASDVADLVGALSKLFRI 428 Query: 459 NFKWSGEYVKLRDEIRHIENYIEVMNIRFEYPILLELEVDAPYLELEVLKMSLQPVVENS 518 G + L DEI HI+NY+++ ++R++ + L + + L +LK+ LQP+VEN+ Sbjct: 429 GLSKGGTIIPLVDEIEHIKNYLQIQSVRYKNKLNYSLVMPSNMERLSILKIVLQPIVENA 488 Query: 519 VKHAWAAGEEELQNRSIRIQISEADGDIFIAIRDNGFGLTPERLTELHSSIYAKEEPGAD 578 + H +E I I+ + + I IRDNG G+ PE L +L +++ E G Sbjct: 489 IYHGI---KERRGPGLITIEAERENDMLIIRIRDNGKGIKPETLQQLRTNVNLFLEKGDK 545 Query: 579 ASXXXXXXXXXXXXXLRNVHQRLQLFYGEAYGLEVQSQAGEWTTVFMTLPKVLLTGDRQT 638 L NVH RL+L +GE YG+++ S E T V + P +L G +T Sbjct: 546 EG----GQRLTKGYGLINVHARLRLTFGEPYGVKIDSVFNEGTVVTIFHP--ILEGGVET 599 >ref|NP_388576.1| similar to two-component sensor histidine kinase [YesN] [Bacillus subtilis] pir||D69796 two-component sensor histidine kinase homolog yesM - Bacillus subtilis emb|CAB12514.1| yesM [Bacillus subtilis subsp. subtilis str. 168] Length = 577 Score = 139 bits (349), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 141/617 (22%), Positives = 265/617 (42%), Gaps = 63/617 (10%) Query: 22 WWGRRSLQSRLVAAYIFIILGPCLLVS-LYSYKSIN---NTYVRDAVDKNSYLLQMEKLH 77 W+ R ++ +L F+ L + VS L+ Y + + Y K+S +L+M Sbjct: 8 WYRRMKIKDKL-----FVFLSLIMAVSFLFVYSGVQYAFHVYDEQIYRKSSEVLRMSSER 62 Query: 78 ILNQIEAMERAAQMAYSDKAVQNYLLNEHDPSLGELIDFNTTTFMNLSRIQINNPNIEHL 137 I ++++ +E + +D+ +Q L ++ + + L+ + I+ + Sbjct: 63 IEDELKKIEDVSYEIITDEQIQRILSMQNRDDTYDQYQMKQELWDQLAGYASDEKYIDSI 122 Query: 138 RLYSGSGEVHELWPIIFREERVSMEPWFQKALKLEGQELW-SFQNEDPDLMQRYSGDPPK 196 + G + + E F++A G+ LW + DP L+ S + Sbjct: 123 HVIDARGSEYSAGSSSSDLLQQEQEEVFKRAKAKSGRNLWMTLGGSDPVLI---SARQIR 179 Query: 197 GQPKVSLLREISIPAGHHVGMIQVDMLLSRFTPKTYTDVRDNQSQMFIAGEDLQL-FTRA 255 ++SL + +GM+ + + + + D D+ + IA + L +T Sbjct: 180 SYHQLSL---------NGLGMVLIQVNVKQMIRDVPKDWGDSVGDIMIADQGGNLVYTAH 230 Query: 256 DHSFVQDNPQLTGAIAGRLQQYAETGEWDIHYKEKGNSFLLIHTPLTEIGASLVNVVSME 315 + V + + T G +D+ K+ G + + + + S NV+ + Sbjct: 231 ASAHVPEAAKETLKHPG----------YDL-IKKNGKRYFISYLQSSYQNWSYYNVIPFD 279 Query: 316 GVMKDISHTRNLIIGLNIGFIVLVTAIAYVLNAFILKNLRRLTETMKKARRGEAYTGFSI 375 + IS + +I + F +V + I + + +L MK + G S+ Sbjct: 280 QMFAKISFMKTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVSL 339 Query: 376 ----RGGGEVGELAHHFSKLMNTINTLVAQAVNKEALSKEAELRTLHNQIDAHFLYNTLE 431 E G L HF+ +M IN L+ + V K+ + KE EL+ L QI+ HFLYNTLE Sbjct: 340 SLPEHTQDEAGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTLE 399 Query: 432 NIKMLAEIENQRGISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIENYIEVMNIRFEYPI 491 +I LA+ Q+ IS + SLG ++R + + V +++E + +Y+ + RFE + Sbjct: 400 SINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEERL 459 Query: 492 LLELEVDAPYLELEVLKMSLQPVVENSVKHAWAAGEEELQNRSIRIQISEADGDIFIAIR 551 L++D + K++LQP+ EN++++A E + +IRIQ +A G + I + Sbjct: 460 KFTLDIDDEVKHCLIPKLTLQPLAENAIQYAL---EPFTRPCAIRIQAKKAKGCVCITVE 516 Query: 552 DNGFGLTPERLTELHSSIYAKEEPGADASXXXXXXXXXXXXXLRNVHQRLQLFYGEAYGL 611 DNG G+ L E G L N+ +R+ L +GE YGL Sbjct: 517 DNGPGMDGRIL----------ESTGGRG------------IGLWNIRERISLTFGEPYGL 554 Query: 612 EVQSQAGEWTTVFMTLP 628 + S+ + T + +T+P Sbjct: 555 RIHSEHEKGTRIVITIP 571 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.319 0.135 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 892,063,633 Number of extensions: 36476959 Number of successful extensions: 97631 Number of sequences better than 1.0e-05: 155 Number of HSP's gapped: 97418 Number of HSP's successfully gapped: 155 Length of query: 638 Length of database: 757,237,578 Length adjustment: 132 Effective length of query: 506 Effective length of database: 398,844,510 Effective search space: 201815322060 Effective search space used: 201815322060 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)