BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0015.p (601 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_242775.1| two-component sensor histidine kinase [Bacillus... 490 e-137 ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halo... 234 4e-60 ref|NP_244545.1| two-component sensor histidine kinase [Bacillus... 174 5e-42 ref|NP_782429.1| two-component sensor kinase yesM [Clostridium t... 167 8e-40 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 165 3e-39 >ref|NP_242775.1| two-component sensor histidine kinase [Bacillus halodurans] pir||E83888 two-component sensor histidine kinase BH1909 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05628.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 597 Score = 490 bits (1262), Expect = e-137, Method: Compositional matrix adjust. Identities = 256/598 (42%), Positives = 388/598 (64%), Gaps = 4/598 (0%) Query: 7 MYARIITSMNNLRLRTKLFLSFGCVALIPVLIVGVFLTSELRNMAMDNALKQITANVDRV 66 MY+ +I ++N+++LR KL F V P++IVG+FLT+ELR+ A+ +A++Q NV+RV Sbjct: 1 MYSTLIQTINDMKLRDKLMFMFVVVVFFPMMIVGIFLTNELRSNAIQDAIQQSRVNVERV 60 Query: 67 KKRTGELLDVPLDIAYRLSNDSRLEEAANHRYVSVYDVVQAYWNYPDFREFVRLYREISS 126 K+RT E+L+VP+ IA L D R E N Y + YDVV AY Y +F +++ Y EI + Sbjct: 61 KERTTEVLNVPVLIANNLQFDERFIELVNQEYETTYDVVDAYLQYMNFTNYLQYYSEIHN 120 Query: 127 IRLYIDNPTVLDNWEFLQADGTVTQEPWYRTALAQKGMVCWNYIRD-NRDGRYYLSLIRK 185 ++ Y +N ++++NW + + +E W++ A+A W Y+ D + + YLS++++ Sbjct: 121 MKYYSENTSLMNNWVIIPVEHEAGEE-WFKEAMADPAYYRWFYLEDETKKNQAYLSMVKR 179 Query: 186 VNFFKQRTSGVLVVNVNTDRLNGILNQESFETLIVDENDNIVASNRTELLGQTLND-LNF 244 +NF + ++GVLV+ V+ +L+ IL QESF T+IVDE + I A+N+ E +G+ L++ ++F Sbjct: 180 LNFLEYGSAGVLVITVDPRKLDRILQQESFTTMIVDERNRIAATNQREYIGKDLHEVIDF 239 Query: 245 KAESAAGPGFYDVSIDGKPFTMLIDDWQPGGSLNSLRIISIFSVESIVKEPNRXXXXXXX 304 GP Y+ ++G+P +++D S + L+IISI + E I+K+ R Sbjct: 240 HEMIQEGPAIYEGKMNGEPSQIIVDYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGAT 299 Query: 305 XXXXXXXXXXXXXYYFSRLLTGRMLQLSKHISKVGSGNLGATLVIDGKDEIGQLARQFNH 364 +FS L++ R+ LS+ I++V SG+L +V+DGKDEIGQL+ QFN Sbjct: 300 VTMGGMAVAVLLIVHFSWLISKRLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQ 359 Query: 365 MVRNINDLMSEVQESNRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVRGQA 424 MV N+ L+ +V E+NRQK + QNEIK KM+ASQINPHFLFN LESIRMK+H++G+ Sbjct: 360 MVANLRSLIHQVHETNRQKRLLEKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGET 419 Query: 425 DISQVVRLLGKMMRKNLEVGNRRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPKANL 484 +I++VV+ LGK+MRK+LEV I L++EL+ V CYL IQ FRY DRL YEL+IDP++ + Sbjct: 420 EIAKVVKQLGKLMRKSLEVTGHHIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEM 479 Query: 485 VQIPPLIIQPLVENSVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMHEIR 544 V+I PLIIQPLVEN+V+HGLE DGG V + + L V V+D+G G+ + ++ I+ Sbjct: 480 VEILPLIIQPLVENAVIHGLERTEDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKLEAIQ 539 Query: 545 QMLESKDDYESNNIGMRNIHLRLKLTYGPECGLTLASQEGFGTQISFEIP-LRSDSYV 601 ML + + N IG+ N+H RL+LTYG GL + S +G GT + F I +R D V Sbjct: 540 NMLHHPQEVDGNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTISQIRGDDDV 597 >ref|NP_242976.1| BH2110~unknown conserved protein [Bacillus halodurans] pir||F83913 hypothetical protein BH2110 [imported] - Bacillus halodurans (strain C-125) dbj|BAB05829.1| BH2110~unknown conserved protein [Bacillus halodurans] Length = 585 Score = 234 bits (597), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 162/593 (27%), Positives = 300/593 (50%), Gaps = 34/593 (5%) Query: 14 SMNNLRLRTKLFLSFGCVALIPVLIVGVFLTSELRNMAMDNALKQITANVDRVKKRTGEL 73 S+NN++LR KL L + +P+L+ + + N + I VD++ Sbjct: 7 SLNNVKLRNKLLLLYIFCVFLPILLTNIIFYNVTANNIKAQKMDDIELVVDQITNEFNNA 66 Query: 74 LDVPLDIAYRLSNDSRLEEAANHRYVSVYDVVQAYWNY-PDFREFVRLYREISSIRLYID 132 +D + I+ ++R+ + Y + D ++AY Y ++ F LY I SI Y D Sbjct: 67 VDQAIGISSGFYTNTRIYDFFETEYETAIDYIEAYDFYLREYSRFSPLYYSIQSISFYTD 126 Query: 133 NPTVLDNWEFLQADGT------VTQEPWYRTALAQKGMVCWNYIRDNRDGRYYL-SLIRK 185 NP+ F+ A G +E WYR + IR N L S+IR+ Sbjct: 127 NPS------FIYAGGIRPLTEHTKEEKWYRLLTEANHPII---IRTNPATDSGLFSVIRE 177 Query: 186 VNFFKQRTSGVLVVNVNTDRLN--GILNQESF--ETLIVDENDNIVASNRTELLGQTLND 241 +++ K + + +V ++ + L I N +F E +++ NI S+ E+ +T Sbjct: 178 LDYHKNKYNHKKIVRIDLNPLTIKQIFNNAAFTGEVYLLNGERNIEFSSNEEVNWRT-EQ 236 Query: 242 LNFKAESAAGPGFYDVSIDGKPFTMLIDDWQPGGSLNSLRIISIFSVESIVKEPNRXXXX 301 L+F A F + +I K ML ++ G R+ S I++E + Sbjct: 237 LHFDALE-----FPEDTIFTKE-RMLSQNYLEG-----WRVAGTISENEILEELYKSREF 285 Query: 302 XXXXXXXXXXXXXXXXYYFSRLLTGRMLQLSKHISKVGSGNLGATLVIDGKDEIGQLARQ 361 S+ + R+L++ KH+ ++ KDEIG+L + Sbjct: 286 IVILASINLLFPTLLIVLISKSIHSRLLRVLKHMKRMKKQKFDIINFPGDKDEIGELTNE 345 Query: 362 FNHMVRNINDLMSEVQESNRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVR 421 FN M + IN L++EV SN +K + L++ + + + SQINPHFLFNALE+IRM++ ++ Sbjct: 346 FNKMSQTINRLINEVYASNIEKKDLQLREKQAQLSALQSQINPHFLFNALETIRMRSMIK 405 Query: 422 GQADISQVVRLLGKMMRKNLEVGNRRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPK 481 G+ + +++++ + K+ R +L G ++++ EL + C+L IQK+R+ D++ YEL ID + Sbjct: 406 GEKETAKIIQNMAKIFRNSLTWGKDWVTVRDELCLIICFLEIQKYRFGDKMEYELDIDEE 465 Query: 482 ANLVQIPPLIIQPLVENSVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMH 541 A IP ++ P VEN+ +HG+E+ + G++++ + DG + ++SDNGAG+ + ++ Sbjct: 466 AYDYIIPNMVFLPFVENASIHGIESVKEKGIIQIRVEKNDGEIVYEISDNGAGMDEEKLA 525 Query: 542 EIRQMLESKDDYESNNIGMRNIHLRLKLTYGPECGLTLASQEGFGTQISFEIP 594 + + L+++++ N+G++N++ RLKL Y ++ S+ G GT + ++P Sbjct: 526 SLIETLKNEENM-GENVGIKNVYYRLKLHYKNHFDFSINSRPGQGTTVQIKLP 577 >ref|NP_244545.1| two-component sensor histidine kinase [Bacillus halodurans] pir||F84109 two-component sensor histidine kinase BH3678 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07397.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 605 Score = 174 bits (442), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 158/601 (26%), Positives = 268/601 (44%), Gaps = 60/601 (9%) Query: 20 LRTKLFLSFGCVALIPVLIVGVFLTSELRNMAMDNALKQITANVDRVKKRTGELLDVPLD 79 LR ++F++F V ++ +L VG + + ++ NA KQ+ R + Sbjct: 23 LRNQIFINFISVMVVVLLFVGFITFNLVMDILKGNAEKQMEQTAIETLHRVDSQFEAIEM 82 Query: 80 IAYRLSNDSRLE-----EAANHRYV-----SVYDVVQAYWNYPDFREFVRLYREISSIRL 129 I +++ + ++ EA H S+ V+ +Y Y I+S L Sbjct: 83 IMSQIATNGSIQQLLYNEANGHPTTFEQRQSMNQVINSYQAY---------ITGITSFEL 133 Query: 130 YIDNPTVLDNWEFLQADGTVTQEPWYRTALAQKGMVCWNYIRDNRDGRYYLSLIRKVNFF 189 Y + L L + E W AL + G V W+ I D D +L+L +KVN Sbjct: 134 YFTDYRRLFPLNELPLPSRIRYE-WIEMALEENGRVVWSGI-DPLDADSFLTL-KKVNLL 190 Query: 190 KQRTS--GVLVVNVNTDRL-----NGILNQESFETLIVDENDNIVASNRTELLGQTLNDL 242 Q S G LV VNT+ NG L+ ++ + D+ + +N E Sbjct: 191 DQDFSHGGYLVSKVNTNYFELRQENGQLDMDNQYVALFDQQGQFITTNMPE--------- 241 Query: 243 NFKAESAAGPGFYDVSIDGKPFTMLIDDWQPGGSLNSLRIISIFSVESIVKEPNRXXXXX 302 + + A V++DG + + + + ++ V S+ + Sbjct: 242 EWHDQIAPKTDKQVVTMDGTDYVRV----EAASNKTGWSLLIYTPVHSLAQGITGIGTAI 297 Query: 303 XXXXXXXXXXXXXXXYYFSRLLTGRMLQLSKHISKVGS-GNLGATLVIDGKDEIGQLARQ 361 Y+ S L+T + +L+ H + G+ G L + I E+ +L Sbjct: 298 LVAGGIGLLIFTISTYFLSSLITNPIQRLT-HAMRFGTLGALKESPSIASTVELNELNDT 356 Query: 362 FNHMVRNINDLMSEVQESNRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVR 421 +N MV N L+ V E L Q+ + K + SQINPHFLFN LE++ + Sbjct: 357 YNRMVETTNYLIKVVYEQE-------LTQSRAELKALQSQINPHFLFNTLEALYWSLEEK 409 Query: 422 GQADISQVVRLLGKMMRKNLE--VGNRRISLQSELETVSCYLVIQKFRYDDRLAYELHID 479 + ++VV L ++ R + G+ ++L E + + YL I K RYD RLA+E+ +D Sbjct: 410 DEEQ-AEVVIALAELFRYTISDVKGDDWVALHEEFDHIERYLHIMKLRYDHRLAWEIELD 468 Query: 480 PKANLVQIPPLIIQPLVENSVVHGLENRIDGGMVRVD--IRIEDGLLKVQVSDNGAGISK 537 P VQIP L+IQP+VEN+++HG+ N++DGG V+V ++ G + + V D+G G+ + Sbjct: 469 PSLREVQIPKLLIQPVVENAIIHGIGNKVDGGKVQVSAYTSVKQGYVNITVRDDGQGMDE 528 Query: 538 TRMHEIRQMLESKDDY--ESNNIGMRNIHLRLKLTYG--PECGLTLASQEGFGTQISFEI 593 ++ LE++ + + + I + NI RL L Y P + L S+ G GT ++F I Sbjct: 529 KTKQKLEHSLETRVGHPEKRSGIALVNIRQRLDLCYASDPHTSIELTSRHGVGTTVTFTI 588 Query: 594 P 594 P Sbjct: 589 P 589 >ref|NP_782429.1| two-component sensor kinase yesM [Clostridium tetani E88] gb|AAO36366.1| two-component sensor kinase yesM [Clostridium tetani E88] Length = 577 Score = 167 bits (423), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 96/277 (34%), Positives = 157/277 (56%), Gaps = 16/277 (5%) Query: 324 LTGRMLQLSKHISKVGSGNLGATLVIDGKDEIGQLARQFNHMVRNINDLMSEVQESNRQK 383 L ML++SK GN + I DEI L + FN M+ +I L+++V + +QK Sbjct: 313 LKSNMLEISK-------GNFDSYYEIKNNDEISILGQVFNQMLTDIKRLINKVYQVEKQK 365 Query: 384 NAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVRGQADISQVVRLLGKMMRKNLEV 443 + + +++ SQINPHFL+N L++I+ KA ++ ++ L R +L Sbjct: 366 RSA-------ELRVLQSQINPHFLYNTLDTIQWKALEYNAFEVVDMINYLSNFFRISLSD 418 Query: 444 GNRRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPKANLVQIPPLIIQPLVENSVVHG 503 G I++ E+ VS YL IQK RY D+++Y + +D + IP LI+QPLVENS+ HG Sbjct: 419 GKEFITISDEVAHVSNYLEIQKIRYKDKISYSMDVDSSLDQYLIPKLIVQPLVENSIYHG 478 Query: 504 LENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMHEIRQMLESKDDYESNNIGMRNI 563 L+ + G++ V I +DG L ++V DNG G+ ++ +R+ L + E+N+ G+ NI Sbjct: 479 LKLQKHKGIINVSISSKDGFLFIKVIDNGLGMDVEQLRTLRKNLW--ESIETNHYGLYNI 536 Query: 564 HLRLKLTYGPECGLTLASQEGFGTQISFEIPLRSDSY 600 + RLKL +G + + + S+ GTQ+ IPL S+ + Sbjct: 537 NERLKLAFGKKYSIEIKSELKIGTQVLLRIPLISEGF 573 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 165 bits (417), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 95/278 (34%), Positives = 157/278 (56%), Gaps = 9/278 (3%) Query: 319 YFSRLLTGRMLQLSKHISKVGSGNLGATLVID--GKDEIGQLARQFNHMVRNINDLMSEV 376 YFSR LT + +L+ + KV GNL + + KDEI + +++N MV INDL++ + Sbjct: 319 YFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRMVERINDLINRI 378 Query: 377 QESNRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVRGQADISQVVRLLGKM 436 + + + + E + K + +QINPHFL+N L++I KA ++S+++ L ++ Sbjct: 379 LK-------LEINKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYSLSRL 431 Query: 437 MRKNLEVGNRRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPKANLVQIPPLIIQPLV 496 R L G I ++ E E + YL +Q RY ++ Y + I + IP LI+QP V Sbjct: 432 FRLTLNRGEEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKLILQPFV 491 Query: 497 ENSVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMHEIRQMLESKDDYESN 556 EN++VHGLEN + V V E LK + DNG G+S+ + ++++ +ES++ E Sbjct: 492 ENAIVHGLENNSEESFVEVIGEKEGENLKFIIKDNGPGMSEETLEKLKRFIESENIEEKV 551 Query: 557 NIGMRNIHLRLKLTYGPECGLTLASQEGFGTQISFEIP 594 +RN++ RL+L YG + L + S++G GT IS +P Sbjct: 552 GYAIRNVNERLRLYYGDKYELKIESRQGEGTTISLILP 589 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.321 0.138 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 791,680,107 Number of extensions: 31583294 Number of successful extensions: 96298 Number of sequences better than 1.0e-05: 191 Number of HSP's gapped: 96073 Number of HSP's successfully gapped: 191 Length of query: 601 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 470 Effective length of database: 401,559,609 Effective search space: 188733016230 Effective search space used: 188733016230 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 129 (54.3 bits)