BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0057.0014.p (254 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_469837.1| similar to 3-dehydroquinate dehydratase [Lister... 304 1e-81 ref|NP_464019.1| similar to 3-dehydroquinate dehydratase [Lister... 303 3e-81 pir||S15652 3-dehydroquinate dehydratase (EC 4.2.1.10) aroD - Sa... 292 5e-78 ref|NP_456161.1| 3-dehydroquinate dehydratase [Salmonella enteri... 289 3e-77 ref|NP_416208.1| 3-dehydroquinate dehydratase [Escherichia coli ... 285 5e-76 >ref|NP_469837.1| similar to 3-dehydroquinate dehydratase [Listeria innocua] sp|Q92EG6|AROD_LISIN 3-dehydroquinate dehydratase (3-dehydroquinase) (Type I DHQase) pir||AF1494 3-dehydroquinate dehydratase homolog lin0494 [imported] - Listeria innocua (strain Clip11262) emb|CAC95726.1| lin0494 [Listeria innocua] Length = 252 Score = 304 bits (779), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 147/250 (58%), Positives = 185/250 (74%), Gaps = 1/250 (0%) Query: 5 VTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVRK 64 V VKNVT GEG PKICV ++ K + D+VEWR DFF +V+DL V+ Sbjct: 4 VVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLKTIDLDVVEWRVDFFEDVKDLVKVKA 63 Query: 65 TLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEENV 124 L EI ++LP+TP++FTFRSA+EGGE ++ E+Y LN+ A +G +D++DVELFNEE Sbjct: 64 ALDEIRAILPETPILFTFRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEAD 123 Query: 125 VRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVLT 184 V L+ AH V V++SNHDF TP++EEIVSRL + +ALG DLPKIAVMP+ AGDVLT Sbjct: 124 VLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGDVLT 183 Query: 185 LLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAELR 244 LL ATNT+ E+ A++PIITMSMAG GVISRLAGE+FGSA+TFGAA K SAPGQ+ V ELR Sbjct: 184 LLDATNTVSEK-ANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELR 242 Query: 245 RVLELLHRSL 254 VL+LLH+ Sbjct: 243 HVLDLLHKQF 252 >ref|NP_464019.1| similar to 3-dehydroquinate dehydratase [Listeria monocytogenes EGD-e] sp|Q8Y9N4|AROD_LISMO 3-dehydroquinate dehydratase (3-dehydroquinase) (Type I DHQase) pir||AD1136 3-dehydroquinate dehydratase homolog lmo0491 [imported] - Listeria monocytogenes (strain EGD-e) emb|CAC98570.1| lmo0491 [Listeria monocytogenes] Length = 252 Score = 303 bits (775), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 147/250 (58%), Positives = 185/250 (74%), Gaps = 1/250 (0%) Query: 5 VTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVRK 64 V VKNVT GEG PKICV ++ + + D+VEWR DFF +V+DLA V Sbjct: 4 VVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEA 63 Query: 65 TLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEENV 124 L EI ++LP+TP++FTFRSA+EGGE ++ E+Y LN+ A +G +D++DVELFNEE Sbjct: 64 ALGEIRAILPETPILFTFRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEAD 123 Query: 125 VRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVLT 184 V L+ AH V V++SNHDF TP++EEIVSRL + +ALG DLPKIAVMP+ AGDVLT Sbjct: 124 VLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGDVLT 183 Query: 185 LLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAELR 244 LL ATNT+ E+ A++PIITMSMAG GVISRLAGE+FGSA+TFGAA K SAPGQ+ V ELR Sbjct: 184 LLDATNTVFEK-ANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELR 242 Query: 245 RVLELLHRSL 254 VL+LLH+ Sbjct: 243 HVLDLLHKQF 252 >pir||S15652 3-dehydroquinate dehydratase (EC 4.2.1.10) aroD - Salmonella typhi pdb|1QFE|A Chain A, The Structure Of Type I 3-Dehydroquinate Dehydratase From Salmonella Typhi pdb|1QFE|B Chain B, The Structure Of Type I 3-Dehydroquinate Dehydratase From Salmonella Typhi pdb|1L9W|A Chain A, Crystal Structure Of 3-Dehydroquinase From Salmonella Typhi Complexed With Reaction Product pdb|1L9W|B Chain B, Crystal Structure Of 3-Dehydroquinase From Salmonella Typhi Complexed With Reaction Product pdb|1L9W|C Chain C, Crystal Structure Of 3-Dehydroquinase From Salmonella Typhi Complexed With Reaction Product pdb|1L9W|D Chain D, Crystal Structure Of 3-Dehydroquinase From Salmonella Typhi Complexed With Reaction Product pdb|1GQN|A Chain A, Native 3-Dehydroquinase From Salmonella Typhi emb|CAA38418.1| 5-dehydroquinate hydrolyase (3-dehydroquinase) [Salmonella typhi] Length = 252 Score = 292 bits (747), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 142/250 (56%), Positives = 180/250 (72%) Query: 4 TVTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVR 63 TVTVKN+ +GEG+PKI VSL+ +E D++EWR D F ++ +V Sbjct: 3 TVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVL 62 Query: 64 KTLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEEN 123 I +PD PL+FTFRSA+EGGE+ ITT++Y+ LN+AA +SG VD+ID+ELF + Sbjct: 63 TAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDA 122 Query: 124 VVRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVL 183 V+ V AHA V+V++SNHDFH TPS EE+VSRLR+ QALG D+PKIAVMPQ DVL Sbjct: 123 DVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVSRLRKMQALGADIPKIAVMPQSKHDVL 182 Query: 184 TLLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAEL 243 TLL AT M++ YADRP+ITMSMA EGVISRLAGE+FGSA TFGA + SAPGQ+AV +L Sbjct: 183 TLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKQASAPGQIAVNDL 242 Query: 244 RRVLELLHRS 253 R VL +LH + Sbjct: 243 RSVLMILHNA 252 >ref|NP_456161.1| 3-dehydroquinate dehydratase [Salmonella enterica subsp. enterica serovar Typhi] ref|NP_805037.1| 3-dehydroquinate dehydratase [Salmonella enterica subsp. enterica serovar Typhi Ty2] sp|P24670|AROD_SALTI 3-dehydroquinate dehydratase (3-dehydroquinase) (Type I DHQase) pir||AI0703 3-dehydroquinate dehydratase (EC 4.2.1.10) [imported] - Salmonella enterica subsp. enterica serovar Typhi (strain CT18) emb|CAD02002.1| 3-dehydroquinate dehydratase [Salmonella enterica subsp. enterica serovar Typhi] gb|AAO68886.1| 3-dehydroquinate dehydratase [Salmonella enterica subsp. enterica serovar Typhi Ty2] Length = 252 Score = 289 bits (740), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 141/250 (56%), Positives = 179/250 (71%) Query: 4 TVTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVR 63 TVTVKN+ +GEG+PKI VSL+ +E D++EWR D F ++ +V Sbjct: 3 TVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDILEWRVDHFMDIASTQSVL 62 Query: 64 KTLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEEN 123 I +PD PL+FTFRSA+EGGE+ ITT++Y+ LN+AA +SG VD+ID+ELF + Sbjct: 63 TAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNRAAIDSGLVDMIDLELFTGDA 122 Query: 124 VVRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVL 183 V+ V AHA V+V++SNHDFH TPS EE+V RLR+ QALG D+PKIAVMPQ DVL Sbjct: 123 DVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRKMQALGADIPKIAVMPQSKHDVL 182 Query: 184 TLLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAEL 243 TLL AT M++ YADRP+ITMSMA EGVISRLAGE+FGSA TFGA + SAPGQ+AV +L Sbjct: 183 TLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEVFGSAATFGAVKQASAPGQIAVNDL 242 Query: 244 RRVLELLHRS 253 R VL +LH + Sbjct: 243 RSVLMILHNA 252 >ref|NP_416208.1| 3-dehydroquinate dehydratase [Escherichia coli K12] sp|P05194|AROD_ECOLI 3-dehydroquinate dehydratase (3-dehydroquinase) (Type I DHQase) pir||DWECDQ 3-dehydroquinate dehydratase (EC 4.2.1.10) aroD - Escherichia coli (strain K-12) emb|CAA42091.1| 3-dehydroquinate dehydratase [Escherichia coli] dbj|BAA15448.1| 3-dehydroquinate dehydratase (EC 4.2.1.10) [Escherichia coli] gb|AAC74763.1| 3-dehydroquinate dehydratase [Escherichia coli K12] Length = 252 Score = 285 bits (730), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 138/250 (55%), Positives = 182/250 (72%) Query: 4 TVTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVR 63 TVTVK++ +G G PKI VSL++ +E D++EWR D +A++ ++ +V Sbjct: 3 TVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDILEWRVDHYADLSNVESVM 62 Query: 64 KTLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEEN 123 + +P+ PL+FTFRSA+EGGE+ I+TE YI LN+AA +SG VD+ID+ELF ++ Sbjct: 63 AAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDD 122 Query: 124 VVRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVL 183 V+E VA AHA V V++SNHDFH TP EEI++RLR+ Q+ D+PKIA+MPQ DVL Sbjct: 123 QVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVL 182 Query: 184 TLLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAEL 243 TLLAAT M+EQYADRPIITMSMA GVISRLAGE+FGSA TFGA K SAPGQ++V +L Sbjct: 183 TLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDL 242 Query: 244 RRVLELLHRS 253 R VL +LH++ Sbjct: 243 RTVLTILHQA 252 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.134 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 328,121,616 Number of extensions: 11920311 Number of successful extensions: 30774 Number of sequences better than 1.0e-05: 63 Number of HSP's gapped: 30721 Number of HSP's successfully gapped: 63 Length of query: 254 Length of database: 757,237,578 Length adjustment: 123 Effective length of query: 131 Effective length of database: 423,280,401 Effective search space: 55449732531 Effective search space used: 55449732531 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)