BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0043.0024.p (598 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_244545.1| two-component sensor histidine kinase [Bacillus... 476 e-133 ref|NP_388576.1| similar to two-component sensor histidine kinas... 173 1e-41 ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongen... 155 3e-36 ref|NP_244314.1| two-component sensor histidine kinase [Bacillus... 151 5e-35 ref|NP_621979.1| predicted ATPase [Thermoanaerobacter tengcongen... 149 1e-34 >ref|NP_244545.1| two-component sensor histidine kinase [Bacillus halodurans] pir||F84109 two-component sensor histidine kinase BH3678 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07397.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 605 Score = 476 bits (1225), Expect = e-133, Method: Compositional matrix adjust. Identities = 248/587 (42%), Positives = 364/587 (62%), Gaps = 4/587 (0%) Query: 3 GKIKELNTLRNQIFIGFLLVMLIIIAVSGAFVYNRVSYLLKNNAERHIQQTAVQANGRLD 62 GK K+ NTLRNQIFI F+ VM++++ G +N V +LK NAE+ ++QTA++ R+D Sbjct: 15 GKRKKWNTLRNQIFINFISVMVVVLLFVGFITFNLVMDILKGNAEKQMEQTAIETLHRVD 74 Query: 63 ALIGQIDSLMEQVANHPTIQQLLTEELDGKSVTFNQRQSLLQIISSYQAYMPSVGSLELY 122 + I+ +M Q+A + +IQQLL E +G TF QRQS+ Q+I+SYQAY+ + S ELY Sbjct: 75 SQFEAIEMIMSQIATNGSIQQLLYNEANGHPTTFEQRQSMNQVINSYQAYITGITSFELY 134 Query: 123 TADYRLLFPIRDGSLETRINSAYITSANTKKGRLVWIGVDPKDEESLLAIRQVSLMDRWF 182 DYR LFP+ + L +RI +I A + GR+VW G+DP D +S L +++V+L+D+ F Sbjct: 135 FTDYRRLFPLNELPLPSRIRYEWIEMALEENGRVVWSGIDPLDADSFLTLKKVNLLDQDF 194 Query: 183 SRGGYLMARIQRSYFQLDDPLSGSD-GGESVLLVNDEGELLGXXXXXXXXXXXXXXXKDQ 241 S GGYL++++ +YF+L D + V L + +G+ + Q Sbjct: 195 SHGGYLVSKVNTNYFELRQENGQLDMDNQYVALFDQQGQFITTNMPEEWHDQIAPKTDKQ 254 Query: 242 TVSFRGKEYVQVKLRSDKTNWTLLVLTPVSYVTRGLSVLRTVLLVSGGFGTLLFLIMSFV 301 V+ G +YV+V+ S+KT W+LL+ TPV + +G++ + T +LV+GG G L+F I ++ Sbjct: 255 VVTMDGTDYVRVEAASNKTGWSLLIYTPVHSLAQGITGIGTAILVAGGIGLLIFTISTYF 314 Query: 302 LSTMITRPIIQLIRAMRKSRLGVLTPNPESVSTIELRELNNTYNGMIANMNDLIRVVYEK 361 LS++IT PI +L AMR LG L +P ST+EL ELN+TYN M+ N LI+VVYE+ Sbjct: 315 LSSLITNPIQRLTHAMRFGTLGALKESPSIASTVELNELNDTYNRMVETTNYLIKVVYEQ 374 Query: 362 EVLQSRTELKALQAQINPHFLFNTLEAFNWSXXXXXXXXXXXXXXXMSRLFRYIIGNPNK 421 E+ QSR ELKALQ+QINPHFLFNTLEA WS ++ LFRY I + Sbjct: 375 ELTQSRAELKALQSQINPHFLFNTLEALYWS-LEEKDEEQAEVVIALAELFRYTISDVKG 433 Query: 422 DEWVTLGEEMEQVQRYLKIMEMRMGDRLSWTIQLGPEEAAVPVPKLLIQPIVENAILHGV 481 D+WV L EE + ++RYL IM++R RL+W I+L P V +PKLLIQP+VENAI+HG+ Sbjct: 434 DDWVALHEEFDHIERYLHIMKLRYDHRLAWEIELDPSLREVQIPKLLIQPVVENAIIHGI 493 Query: 482 ESRVGSGTVSVIVAPAQRKGWTQITVQDNGPGMDADTLQSLYSALEGGPSISAKGTGIGL 541 ++V G V V + ++G+ ITV+D+G GMD T Q L +LE K +GI L Sbjct: 494 GNKVDGGKVQVSAYTSVKQGYVNITVRDDGQGMDEKTKQKLEHSLETRVGHPEKRSGIAL 553 Query: 542 VNVQRRIRLYYEAEGTGVKGLNIESKLSEGTVITFEIPNNGGHTYES 588 VN+++R+ L Y ++ + + S+ GT +TF IP + E+ Sbjct: 554 VNIRQRLDLCYASDPH--TSIELTSRHGVGTTVTFTIPKKEAPSDEA 598 >ref|NP_388576.1| similar to two-component sensor histidine kinase [YesN] [Bacillus subtilis] pir||D69796 two-component sensor histidine kinase homolog yesM - Bacillus subtilis emb|CAB12514.1| yesM [Bacillus subtilis subsp. subtilis str. 168] Length = 577 Score = 173 bits (439), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 171/604 (28%), Positives = 269/604 (44%), Gaps = 81/604 (13%) Query: 11 LRNQIFIGFLLVMLIIIAVSGAFVYNRVSYLLKNNAE---RHIQQTAVQANGRLDALIGQ 67 +++++F+ L+M AVS FVY+ V Y E R + ++ R++ + + Sbjct: 14 IKDKLFVFLSLIM----AVSFLFVYSGVQYAFHVYDEQIYRKSSEVLRMSSERIEDELKK 69 Query: 68 IDSLMEQVANHPTIQQLLTEELDGKSVTFNQ---RQSLLQIISSY---QAYMPSVGSLEL 121 I+ + ++ IQ++L+ + + T++Q +Q L ++ Y + Y+ S+ ++ Sbjct: 70 IEDVSYEIITDEQIQRILS--MQNRDDTYDQYQMKQELWDQLAGYASDEKYIDSIHVIDA 127 Query: 122 YTADYRLLFPIRDGSLETRINSAYITSANTKKGRLVWI---GVDPKDEESLLAIRQVSLM 178 ++Y D L + A K GR +W+ G DP L++ RQ+ Sbjct: 128 RGSEYSAGSSSSD--LLQQEQEEVFKRAKAKSGRNLWMTLGGSDP----VLISARQIRSY 181 Query: 179 DRWFSRGGYLMARIQRSYFQL--DDPLSGSDGGESV--LLVNDEGELLGXXXXXXXXXXX 234 + S G M IQ + Q+ D P D G+SV +++ D+G G Sbjct: 182 HQ-LSLNGLGMVLIQVNVKQMIRDVP---KDWGDSVGDIMIADQG---GNLVYTAHASAH 234 Query: 235 XXXXKDQTVSF--------RGKEYVQVKLRSDKTNWTLLVLTPVSYVTRGLSVLRTVLLV 286 +T+ GK Y L+S NW+ + P + +S ++TV+ Sbjct: 235 VPEAAKETLKHPGYDLIKKNGKRYFISYLQSSYQNWSYYNVIPFDQMFAKISFMKTVI-- 292 Query: 287 SGGFGTLLFLIMSFVL------STMITRPIIQLIRAMRKSR-----LGVLTPNPESVSTI 335 GT L VL + IT PI QL+ AM+ + GV PE Sbjct: 293 ----GTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQD- 347 Query: 336 ELRELNNTYNGMIANMNDLIRVVYEKEVLQSRTELKALQAQINPHFLFNTLEAFNWSXXX 395 E LN + M+ +N+L+ EK+++ TELKALQAQINPHFL+NTLE+ NW Sbjct: 348 EAGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTLESINWLAKA 407 Query: 396 XXXXXXXXXXXXMSRLFRYIIGNPNKDEWVTLGEEMEQVQRYLKIMEMRMGDRLSWTIQL 455 + L R I K + VT+ EE + V+ Y+ I R +RL +T+ + Sbjct: 408 NQQKQISKMVESLGFLLRNSIH--MKKDIVTIQEEADIVRHYMTIQRFRFEERLKFTLDI 465 Query: 456 GPEEAAVPVPKLLIQPIVENAILHGVESRVGSGTVSVIVAPAQRKGWTQITVQDNGPGMD 515 E +PKL +QP+ ENAI + +E + + A KG ITV+DNGPGMD Sbjct: 466 DDEVKHCLIPKLTLQPLAENAIQYALEPFTRPCAIRIQAKKA--KGCVCITVEDNGPGMD 523 Query: 516 ADTLQSLYSALEGGPSISAKGTGIGLVNVQRRIRLYYEAEGTGVKGLNIESKLSEGTVIT 575 L+ S G GIGL N++ RI L + GL I S+ +GT I Sbjct: 524 GRILE------------STGGRGIGLWNIRERISLTFGEP----YGLRIHSEHEKGTRIV 567 Query: 576 FEIP 579 IP Sbjct: 568 ITIP 571 >ref|NP_623881.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM25485.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 593 Score = 155 bits (391), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 101/294 (34%), Positives = 156/294 (53%), Gaps = 16/294 (5%) Query: 290 FGTLLFLIMSFVLSTMITRPIIQLIRAMRKSRLGVLTPNPE--SVSTIELRELNNTYNGM 347 F L ++S S +T P+ +L +M+K R G L E S E+ + YN M Sbjct: 308 FCLLFAFLVSMYFSRALTHPLERLANSMKKVRQGNLEEKVEFEYHSKDEIAIVIKEYNRM 367 Query: 348 IANMNDLIRVVYEKEVLQSRTELKALQAQINPHFLFNTLEAFNWSXXXXXXXXXXXXXXX 407 + +NDLI + + E+ + ELKAL+AQINPHFL+NTL+ W Sbjct: 368 VERINDLINRILKLEINKREAELKALEAQINPHFLYNTLDTIFWKAEKAKDRELSEMIYS 427 Query: 408 MSRLFRYIIGNPNKDEWVTLGEEMEQVQRYLKIMEMRMGDRLSWTIQLGPEEAAVPVPKL 467 +SRLFR + +E++ + E E ++RYL + R ++ +++++ E +PKL Sbjct: 428 LSRLFRLTLNRG--EEFIQVRGEKELIERYLFLQSKRYKNKFKYSVKISDEILDYYIPKL 485 Query: 468 LIQPIVENAILHGVESRVGSGTVSVIVAPAQRKGWT-QITVQDNGPGMDADTLQSLYSAL 526 ++QP VENAI+HG+E+ V VI +++G + ++DNGPGM +TL+ L + Sbjct: 486 ILQPFVENAIVHGLENNSEESFVEVI---GEKEGENLKFIIKDNGPGMSEETLEKLKRFI 542 Query: 527 EGGPSISAKGTGIGLVNVQRRIRLYYEAEGTGVK-GLNIESKLSEGTVITFEIP 579 E +I K G + NV R+RLYY G K L IES+ EGT I+ +P Sbjct: 543 E-SENIEEK-VGYAIRNVNERLRLYY-----GDKYELKIESRQGEGTTISLILP 589 >ref|NP_244314.1| two-component sensor histidine kinase [Bacillus halodurans] pir||G84080 two-component sensor histidine kinase BH3447 [imported] - Bacillus halodurans (strain C-125) dbj|BAB07166.1| two-component sensor histidine kinase [Bacillus halodurans] Length = 602 Score = 151 bits (381), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 100/291 (34%), Positives = 157/291 (53%), Gaps = 22/291 (7%) Query: 299 SFVLSTMITRPIIQLIRAMRKSRLGVLTPNPESVSTIELRELNNTYNGMIANMNDLIRVV 358 S+ LS I+RPI QL+ AM+K+ G LT E E+ L ++N MI + LI + Sbjct: 313 SYFLSYTISRPINQLMLAMQKAESGDLTSRYEGEEQDEVGRLGRSFNTMIEQIGKLISLT 372 Query: 359 YEKEVLQSRTELKALQAQINPHFLFNTLEAFNWSXXXXXXXXXXXXXXXMSRLFRYIIGN 418 +E + EL +LQA I PHFL+NTL+ W +S+LFR IG Sbjct: 373 ERQERKKREAELHSLQANIKPHFLYNTLDTIQWMARKKNASDVADLVGALSKLFR--IGL 430 Query: 419 PNKDEWVTLGEEMEQVQRYLKIMEMRMGDRLSWTIQLGPEEAAVPVPKLLIQPIVENAIL 478 + L +E+E ++ YL+I +R ++L++++ + + + K+++QPIVENAI Sbjct: 431 SKGGTIIPLVDEIEHIKNYLQIQSVRYKNKLNYSLVMPSNMERLSILKIVLQPIVENAIY 490 Query: 479 HGVESRVGSGTVSVIVAPAQRKG-WTQITVQDNGPGMDADTLQSLYSAL---------EG 528 HG++ R G G +++ A+R+ I ++DNG G+ +TLQ L + + EG Sbjct: 491 HGIKERRGPGLITI---EAERENDMLIIRIRDNGKGIKPETLQQLRTNVNLFLEKGDKEG 547 Query: 529 GPSISAKGTGIGLVNVQRRIRLYYEAEGTGVKGLNIESKLSEGTVITFEIP 579 G ++ G GL+NV R+RL + E GVK I+S +EGTV+T P Sbjct: 548 GQRLTK---GYGLINVHARLRLTF-GEPYGVK---IDSVFNEGTVVTIFHP 591 >ref|NP_621979.1| predicted ATPase [Thermoanaerobacter tengcongensis] gb|AAM23583.1| predicted ATPase [Thermoanaerobacter tengcongensis] Length = 493 Score = 149 bits (377), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 99/309 (32%), Positives = 170/309 (55%), Gaps = 22/309 (7%) Query: 283 VLLVSGGFGTLLFLIMSFVLSTMITRPIIQLIR-AMRKSRLGVLTPNPESVST-IELREL 340 ++L+S GF L +F+ + IT+PII L A+R S+ G P + T E++ L Sbjct: 189 LILISIGFSIFL----AFLFTYKITKPIIDLSHLAVRVSK-GDFEVRPIELKTNDEIKVL 243 Query: 341 NNTYNGMIANMNDLIRVVYEKEVLQSR---TELKALQAQINPHFLFNTLEAFNWSXXXXX 397 + +N M+ N+ I + ++ ++ + ELKALQ+QINPHFLFNTL A Sbjct: 244 SEAFNKMVVNIKKYIGEIKKQAEMERKIKEAELKALQSQINPHFLFNTLNAAAQLAMMEG 303 Query: 398 XXXXXXXXXXMSRLFRYIIGNPNK-DEWVTLGEEMEQVQRYLKIMEMRMGDRLSWTIQLG 456 ++ LFRY N K D VTL +E+E V+RY+ I++ R GD++ + + + Sbjct: 304 AEKSAEFIENVANLFRY---NLKKLDSTVTLKDEIENVKRYIYILKTRFGDKIDFKLDVE 360 Query: 457 PEEAAVPVPKLLIQPIVENAILHGVESRVGSGTVSVIVAPAQRKG-WTQITVQDNGPGMD 515 E + +P +++QP+VENA +HG+E G +IV A ++G + + DNG GM+ Sbjct: 361 EEVLDLEMPCMILQPVVENAFIHGLEDVERDG---LIVLKAYKEGEKVLVEIADNGVGME 417 Query: 516 ADTLQSLYSALEGGPSISAKG-TGIGLVNVQRRIRLYYEAEGTGVKGLNIESKLSEGTVI 574 + ++++ + P + K TGIG+ N+ R+ ++Y+ + I+S++ +GT + Sbjct: 418 QEKIKAILAL--DSPDVDKKHVTGIGMHNIIHRLLVFYDISSVE-DVIEIKSEIGKGTKV 474 Query: 575 TFEIPNNGG 583 T +IP+ G Sbjct: 475 TLKIPDKKG 483 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.318 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 804,044,574 Number of extensions: 31816405 Number of successful extensions: 89373 Number of sequences better than 1.0e-05: 176 Number of HSP's gapped: 89137 Number of HSP's successfully gapped: 176 Length of query: 598 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 467 Effective length of database: 401,559,609 Effective search space: 187528337403 Effective search space used: 187528337403 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)