BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0038.0002.p (553 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 2,715,099 sequences; 757,237,578 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value dbj|BAA16250.1| similar to [SwissProt Accession Number P33357] [... 657 0.0 ref|NP_288950.1| putative sensor protein [Escherichia coli O157:... 657 0.0 ref|NP_754801.1| Hypothetical protein ypdA [Escherichia coli CFT... 656 0.0 gb|EAK07599.1| unknown [environmental sequence] 609 e-173 ref|XP_306661.1| ENSANGP00000000879 [Anopheles gambiae] >gi|2128... 536 e-151 >dbj|BAA16250.1| similar to [SwissProt Accession Number P33357] [Escherichia coli] Length = 559 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/535 (60%), Positives = 411/535 (76%), Gaps = 2/535 (0%) Query: 20 MCLFVLTRVPRFKEIFVQGAYAPQELAMVTVIFSLFAIFGTYTGINVEGSLVNVRIIAIV 79 +CLF L R+ F+E+ + A++P+EL VT IFSLFA+F T++G+ VEGSLVNVRIIA++ Sbjct: 14 ICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVM 73 Query: 80 AGGILFGPWVGLITGVISGVHRFLIDIGGITSVPCLITSIAAGMVSGVIYRRTSAEHRWI 139 +GGILFGPWVG+ITGVI+G+HR+LIDIGG+T++PC ITSI AG +SG I + RW Sbjct: 74 SGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWR 133 Query: 140 AGILAGMACEALTMVLILVMANPASLGVDIVSKIAFPMIAGQISVGLIVLLVQSVEGEKE 199 GIL GM CE LTM+L++V A +LG+DIVSKI PMI G + +G IVLLVQSVEGEKE Sbjct: 134 VGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKE 193 Query: 200 RIAAKQSKLALDIANKTLPYFRSITPQSLRIICGIIKEDIGADAVAITDTRYIRAYVGVG 259 AA+Q+KLALDIANKTLP FR + +SLR +C II++DI ADAVAIT+T ++ AYVGVG Sbjct: 194 ASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVG 253 Query: 260 EEYYAETNEIISEETKMTLRSGEITIRDDDTEYMNRAIRSLIIIPLKEKGEVTGALKIYY 319 E Y ++ IS T+ + G+I I+++D + I S+++IPL EKG VTG LKIYY Sbjct: 254 EHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYY 313 Query: 320 TKAHKITYSLQAMAVGLSQIISTLMEVSRVEDIKEMANKAELKALQTSINPHFLFNALNA 379 AH+IT SLQ MAVGLSQIIST +EVSR E ++EMANKAEL+ALQ+ INPHFLFNALNA Sbjct: 314 CHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNA 373 Query: 380 IISSIRIDPDKARELIVNLSGYMRYNLELT-DEFIDIRRELQQVQQYVEIEKARFGSRLA 438 I SSIR++PD AR+LI NLS Y+RYN+EL DE IDI++EL Q++ Y+ IE+ARFG +L Sbjct: 374 ISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLT 433 Query: 439 VEYEID-ELEVRIPSLIIQPLVENAIVHGILKVRGQGTVTISVKDLGSAVRIGITDTGIG 497 V Y+ID E+ IPSL+IQPLVENAIVHGI +G+G VTISV + G+ VRI + DTG G Sbjct: 434 VIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHG 493 Query: 498 ISEETIGKVYSGNMPDHKIGLYNVHQRVKLIYGKGLTIHRLDQGTEIYFDVTKEQ 552 I + I +V + MP +KIGL NVH RVKL+YG+GL I RL+ GTEI F + ++ Sbjct: 494 IDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQR 548 >ref|NP_288950.1| putative sensor protein [Escherichia coli O157:H7 EDL933] ref|NP_311287.1| putative sensor protein [Escherichia coli O157:H7] ref|NP_416881.1| putative sensor protein [Escherichia coli K12] sp|P76523|YPDA_ECOLI Hypothetical protein ypdA pir||A65012 probable sensor protein b2380 [similarity] - Escherichia coli (strain K-12) pir||D91036 probable sensor protein [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) pir||F85880 probable sensor protein Z3645 [imported] - Escherichia coli (strain O157:H7, substrain EDL933) gb|AAC75439.1| putative sensor protein [Escherichia coli K12] gb|AAG57506.1| putative sensor protein [Escherichia coli O157:H7 EDL933] dbj|BAB36683.1| putative sensor protein [Escherichia coli O157:H7] Length = 565 Score = 657 bits (1696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/535 (60%), Positives = 411/535 (76%), Gaps = 2/535 (0%) Query: 20 MCLFVLTRVPRFKEIFVQGAYAPQELAMVTVIFSLFAIFGTYTGINVEGSLVNVRIIAIV 79 +CLF L R+ F+E+ + A++P+EL VT IFSLFA+F T++G+ VEGSLVNVRIIA++ Sbjct: 20 ICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVM 79 Query: 80 AGGILFGPWVGLITGVISGVHRFLIDIGGITSVPCLITSIAAGMVSGVIYRRTSAEHRWI 139 +GGILFGPWVG+ITGVI+G+HR+LIDIGG+T++PC ITSI AG +SG I + RW Sbjct: 80 SGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWR 139 Query: 140 AGILAGMACEALTMVLILVMANPASLGVDIVSKIAFPMIAGQISVGLIVLLVQSVEGEKE 199 GIL GM CE LTM+L++V A +LG+DIVSKI PMI G + +G IVLLVQSVEGEKE Sbjct: 140 VGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKE 199 Query: 200 RIAAKQSKLALDIANKTLPYFRSITPQSLRIICGIIKEDIGADAVAITDTRYIRAYVGVG 259 AA+Q+KLALDIANKTLP FR + +SLR +C II++DI ADAVAIT+T ++ AYVGVG Sbjct: 200 ASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVG 259 Query: 260 EEYYAETNEIISEETKMTLRSGEITIRDDDTEYMNRAIRSLIIIPLKEKGEVTGALKIYY 319 E Y ++ IS T+ + G+I I+++D + I S+++IPL EKG VTG LKIYY Sbjct: 260 EHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYY 319 Query: 320 TKAHKITYSLQAMAVGLSQIISTLMEVSRVEDIKEMANKAELKALQTSINPHFLFNALNA 379 AH+IT SLQ MAVGLSQIIST +EVSR E ++EMANKAEL+ALQ+ INPHFLFNALNA Sbjct: 320 CHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNA 379 Query: 380 IISSIRIDPDKARELIVNLSGYMRYNLELT-DEFIDIRRELQQVQQYVEIEKARFGSRLA 438 I SSIR++PD AR+LI NLS Y+RYN+EL DE IDI++EL Q++ Y+ IE+ARFG +L Sbjct: 380 ISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLT 439 Query: 439 VEYEID-ELEVRIPSLIIQPLVENAIVHGILKVRGQGTVTISVKDLGSAVRIGITDTGIG 497 V Y+ID E+ IPSL+IQPLVENAIVHGI +G+G VTISV + G+ VRI + DTG G Sbjct: 440 VIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHG 499 Query: 498 ISEETIGKVYSGNMPDHKIGLYNVHQRVKLIYGKGLTIHRLDQGTEIYFDVTKEQ 552 I + I +V + MP +KIGL NVH RVKL+YG+GL I RL+ GTEI F + ++ Sbjct: 500 IDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQR 554 >ref|NP_754801.1| Hypothetical protein ypdA [Escherichia coli CFT073] gb|AAN81369.1| Hypothetical protein ypdA [Escherichia coli CFT073] Length = 565 Score = 656 bits (1693), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/535 (60%), Positives = 411/535 (76%), Gaps = 2/535 (0%) Query: 20 MCLFVLTRVPRFKEIFVQGAYAPQELAMVTVIFSLFAIFGTYTGINVEGSLVNVRIIAIV 79 +CLF L R+ F+E+ + A++P+EL VT IFSLFA+F T++G+ VEGSLVNVRIIA++ Sbjct: 20 ICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVM 79 Query: 80 AGGILFGPWVGLITGVISGVHRFLIDIGGITSVPCLITSIAAGMVSGVIYRRTSAEHRWI 139 +GGILFGPWVG+ITGVI+G+HR+LIDIGG+T++PC ITSI AG +SG I + RW Sbjct: 80 SGGILFGPWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWR 139 Query: 140 AGILAGMACEALTMVLILVMANPASLGVDIVSKIAFPMIAGQISVGLIVLLVQSVEGEKE 199 GIL GM CE LTM+L++V A +LG+DIVSKI PMI G + +G IVLLVQSVEGEKE Sbjct: 140 VGILGGMLCETLTMILVIVWAPTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKE 199 Query: 200 RIAAKQSKLALDIANKTLPYFRSITPQSLRIICGIIKEDIGADAVAITDTRYIRAYVGVG 259 AA+Q+KLALDIANKTLP FR + +SLR +C II++DI ADAVA+T+T ++ AYVGVG Sbjct: 200 ASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAMTNTDHVLAYVGVG 259 Query: 260 EEYYAETNEIISEETKMTLRSGEITIRDDDTEYMNRAIRSLIIIPLKEKGEVTGALKIYY 319 E Y ++ IS T+ + G+I I+++D + I S+++IPL EKG VTG LKIYY Sbjct: 260 EHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYY 319 Query: 320 TKAHKITYSLQAMAVGLSQIISTLMEVSRVEDIKEMANKAELKALQTSINPHFLFNALNA 379 AH+IT SLQ MAVGLSQIIST +EVSR E ++EMANKAEL+ALQ+ INPHFLFNALNA Sbjct: 320 CHAHQITSSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNA 379 Query: 380 IISSIRIDPDKARELIVNLSGYMRYNLELT-DEFIDIRRELQQVQQYVEIEKARFGSRLA 438 I SSIR++PD AR+LI NLS Y+RYN+EL DE IDI++EL Q++ Y+ IE+ARFG +L Sbjct: 380 ISSSIRLNPDTARQLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLT 439 Query: 439 VEYEID-ELEVRIPSLIIQPLVENAIVHGILKVRGQGTVTISVKDLGSAVRIGITDTGIG 497 V Y+ID E+ IPSL+IQPLVENAIVHGI +G+G VTISV + G+ VRI + DTG G Sbjct: 440 VIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHG 499 Query: 498 ISEETIGKVYSGNMPDHKIGLYNVHQRVKLIYGKGLTIHRLDQGTEIYFDVTKEQ 552 I + I +V + MP +KIGL NVH RVKL+YG+GL I RL+ GTEI F + ++ Sbjct: 500 IDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQR 554 >gb|EAK07599.1| unknown [environmental sequence] Length = 551 Score = 609 bits (1571), Expect = e-173, Method: Compositional matrix adjust. Identities = 299/534 (55%), Positives = 391/534 (73%), Gaps = 1/534 (0%) Query: 20 MCLFVLTRVPRFKEIFVQGAYAPQELAMVTVIFSLFAIFGTYTGINVEGSLVNVRIIAIV 79 M LF LTR F+ +F + + P EL +V IF LFA+F TYTGI VEG+L+NVRIIAI+ Sbjct: 14 MTLFFLTRTRPFQRLFQKRDHTPAELVLVAAIFCLFAVFSTYTGIPVEGALINVRIIAII 73 Query: 80 AGGILFGPWVGLITGVISGVHRFLIDIGGITSVPCLITSIAAGMVSGVIYRRTSAEHRWI 139 +GGILFGPWVG+ GVISG+HR+LID+ G TS+PCLI SI AG+++ ++ R W+ Sbjct: 74 SGGILFGPWVGIPAGVISGLHRYLIDMDGHTSIPCLIASIIAGLLATWLHLRCRKSRLWL 133 Query: 140 AGILAGMACEALTMVLILVMANPASLGVDIVSKIAFPMIAGQISVGLIVLLVQSVEGEKE 199 GILAGM CE LTM+LI ++ P ++G++IVS IA+PMIAG + +GLI+ LVQ ++ EKE Sbjct: 134 YGILAGMLCEGLTMLLIWLLTEPHAVGIEIVSHIAYPMIAGALCIGLIIKLVQDLDDEKE 193 Query: 200 RIAAKQSKLALDIANKTLPYFRSITPQSLRIICGIIKEDIGADAVAITDTRYIRAYVGVG 259 IAAKQ+KLALDIANKTLP+F++I SL +C II+ +I ADAVAITDTR + AYVGVG Sbjct: 194 LIAAKQAKLALDIANKTLPFFQNIDRHSLSQVCAIIRSEISADAVAITDTRDVLAYVGVG 253 Query: 260 EEYYA-ETNEIISEETKMTLRSGEITIRDDDTEYMNRAIRSLIIIPLKEKGEVTGALKIY 318 ++YY + + IS+ T+ + +I I +D +Y S+IIIPL+E G V+G LKIY Sbjct: 254 KDYYELDEHHAISDMTQRAVLLDQIIINNDLRQYHLADFHSVIIIPLRENGSVSGTLKIY 313 Query: 319 YTKAHKITYSLQAMAVGLSQIISTLMEVSRVEDIKEMANKAELKALQTSINPHFLFNALN 378 Y + H IT SL+ MAVGLSQ+IST MEVSR+E +KEM KAE ALQ+ INPHFLFNALN Sbjct: 314 YRRTHSITSSLREMAVGLSQLISTQMEVSRIEQLKEMTRKAEFTALQSKINPHFLFNALN 373 Query: 379 AIISSIRIDPDKARELIVNLSGYMRYNLELTDEFIDIRRELQQVQQYVEIEKARFGSRLA 438 AI S IRI P +AR+LI NL+ Y+RYNL D IDI+ ELQQV+ YV IE+ARFG +L Sbjct: 374 AISSLIRIRPQQARQLIANLADYLRYNLNKGDTLIDIQEELQQVRDYVAIEQARFGDKLE 433 Query: 439 VEYEIDELEVRIPSLIIQPLVENAIVHGILKVRGQGTVTISVKDLGSAVRIGITDTGIGI 498 V +E+D++ +++PSL++QPLVENAI+HGI G VTI VK L +R+ + DTG GI Sbjct: 434 VVFEVDDVHIQVPSLLLQPLVENAILHGIQPRSAPGRVTIEVKQLAGGIRVAVRDTGYGI 493 Query: 499 SEETIGKVYSGNMPDHKIGLYNVHQRVKLIYGKGLTIHRLDQGTEIYFDVTKEQ 552 S+E I V +G + IGL NVHQRVKL+YG GL + RL+ GTE+ F + ++ Sbjct: 494 SQEVIDGVAAGRVESRSIGLMNVHQRVKLLYGDGLHLKRLEPGTEVSFYLPDQE 547 >ref|XP_306661.1| ENSANGP00000000879 [Anopheles gambiae] gb|EAA02130.1| ENSANGP00000000879 [Anopheles gambiae str. PEST] Length = 472 Score = 536 bits (1380), Expect = e-151, Method: Compositional matrix adjust. Identities = 264/471 (56%), Positives = 345/471 (73%), Gaps = 1/471 (0%) Query: 83 ILFGPWVGLITGVISGVHRFLIDIGGITSVPCLITSIAAGMVSGVIYRRTSAEHRWIAGI 142 ILFGPWVG+ GVISG+HR+LID+ G TS+PCLI SI AG+++ ++ R W+ GI Sbjct: 1 ILFGPWVGIPAGVISGLHRYLIDMDGHTSIPCLIASIIAGLLATWLHLRCRKSRLWLYGI 60 Query: 143 LAGMACEALTMVLILVMANPASLGVDIVSKIAFPMIAGQISVGLIVLLVQSVEGEKERIA 202 LAGM CE LTM+LI ++ P ++GV+IVS IA+PMIAG + +GLI+ LVQ ++ EKE IA Sbjct: 61 LAGMLCEGLTMLLIWLLTEPHAVGVEIVSHIAYPMIAGALCIGLIIKLVQDLDDEKELIA 120 Query: 203 AKQSKLALDIANKTLPYFRSITPQSLRIICGIIKEDIGADAVAITDTRYIRAYVGVGEEY 262 AKQ+KLALDIANKTLP+F++I SL +C II+ +I ADAVAITDTR + AYVGVG++Y Sbjct: 121 AKQAKLALDIANKTLPFFQNIDRHSLSQVCAIIRSEISADAVAITDTRDVLAYVGVGKDY 180 Query: 263 YA-ETNEIISEETKMTLRSGEITIRDDDTEYMNRAIRSLIIIPLKEKGEVTGALKIYYTK 321 Y + + IS+ T+ + +I I +D +Y S+IIIPL+E G V+G LKIYY + Sbjct: 181 YELDEHHAISDMTQRAVLLDQIIINNDLRQYHLSDFHSVIIIPLRENGSVSGTLKIYYRR 240 Query: 322 AHKITYSLQAMAVGLSQIISTLMEVSRVEDIKEMANKAELKALQTSINPHFLFNALNAII 381 H IT SL+ MAVGLSQ+IST MEVSR+E +KEM KAE ALQ+ INPHFLFNALNAI Sbjct: 241 THSITSSLKEMAVGLSQLISTQMEVSRIEQLKEMTRKAEFTALQSKINPHFLFNALNAIS 300 Query: 382 SSIRIDPDKARELIVNLSGYMRYNLELTDEFIDIRRELQQVQQYVEIEKARFGSRLAVEY 441 S IRI P +AR+LI NL+ Y+RYNL D IDI+ ELQQV+ YV IE+ARFG +L V + Sbjct: 301 SLIRIRPQQARQLIANLADYLRYNLNKGDTLIDIQEELQQVRDYVAIEQARFGDKLEVVF 360 Query: 442 EIDELEVRIPSLIIQPLVENAIVHGILKVRGQGTVTISVKDLGSAVRIGITDTGIGISEE 501 E+D++ +++PSL++QPLVENAI+HGI G VTI VK L +R+ + DTG GIS+E Sbjct: 361 EVDDVHIQVPSLLLQPLVENAILHGIQPRSAPGRVTIEVKQLAGGIRVAVRDTGYGISQE 420 Query: 502 TIGKVYSGNMPDHKIGLYNVHQRVKLIYGKGLTIHRLDQGTEIYFDVTKEQ 552 I V +G + IGL NVHQRVKL+YG GL + RL+ GTE+ F + ++ Sbjct: 421 VIDGVAAGRVESRSIGLMNVHQRVKLLYGDGLHLKRLEPGTEVSFYLPDQE 471 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Mar 24, 2004 1:53 AM Number of letters in database: 757,237,578 Number of sequences in database: 2,715,099 Lambda K H 0.322 0.139 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 2715099 Number of Hits to DB: 712,953,885 Number of extensions: 28787758 Number of successful extensions: 89065 Number of sequences better than 1.0e-05: 189 Number of HSP's gapped: 88573 Number of HSP's successfully gapped: 189 Length of query: 553 Length of database: 757,237,578 Length adjustment: 131 Effective length of query: 422 Effective length of database: 401,559,609 Effective search space: 169458154998 Effective search space used: 169458154998 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 128 (53.9 bits)